GREMLIN Database
Q97WB8 - Flagella-related protein J, putative (FlaJ)
UniProt: Q97WB8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 473 (443)
Sequences: 360 (281)
Seq/√Len: 13.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
361_Y437_F5.6651.00
55_I86_L4.5131.00
198_L205_S4.4861.00
22_M35_V4.3351.00
65_K68_S4.0311.00
37_L60_S4.0091.00
294_D297_K3.7090.99
198_L234_L3.4650.99
11_V77_L3.2180.98
55_I70_I3.0050.97
205_S209_S2.8300.96
85_F276_G2.5890.93
199_T203_S2.5630.92
377_I442_I2.5370.92
199_T205_S2.5270.92
164_T411_I2.5030.91
369_G372_A2.4290.90
243_E308_S2.4070.90
77_L130_T2.3600.89
20_A93_V2.3540.89
198_L203_S2.3030.88
133_A426_A2.2810.87
421_I431_L2.2800.87
374_L378_V2.2520.86
18_M22_M2.2380.86
127_N149_L2.2280.86
21_F254_S2.2140.85
8_K435_L2.1840.84
420_G434_S2.1430.83
232_Y433_V2.1110.82
368_A441_L2.1110.82
11_V85_F2.0850.82
62_Y243_E2.0410.80
274_D437_F2.0340.80
70_I86_L2.0240.80
93_V206_I1.9670.77
440_I447_I1.9620.77
201_T205_S1.9550.77
128_F373_A1.9440.77
294_D348_R1.9230.76
211_I217_V1.8830.74
96_G130_T1.8750.74
26_F45_F1.8720.74
369_G374_L1.8690.74
320_E372_A1.8480.73
369_G373_A1.8330.72
297_K445_S1.8200.72
375_I439_G1.8190.72
254_S305_E1.8040.71
282_I450_H1.7920.70
134_T299_F1.7860.70
55_I145_D1.7790.70
88_R102_F1.7780.70
203_S207_I1.7710.69
36_I337_K1.7700.69
369_G418_A1.7230.67
250_I332_G1.7190.67
209_S417_F1.7130.67
379_G383_N1.7110.67
242_I374_L1.6960.66
198_L201_T1.6890.66
424_T434_S1.6840.65
31_P55_I1.6840.65
375_I452_V1.6840.65
52_F82_L1.6630.64
132_Y292_G1.6610.64
45_F302_I1.6520.64
211_I216_I1.6470.64
174_L216_I1.6410.63
164_T441_L1.6190.62
187_Y192_V1.6120.62
200_F289_L1.6040.61
372_A448_S1.6040.61
302_I358_T1.6020.61
170_L298_I1.5920.61
71_T85_F1.5480.59
391_S395_S1.5430.58
274_D361_Y1.5410.58
122_I349_K1.5250.57
226_L384_I1.5250.57
15_Y47_P1.5240.57
125_M429_K1.5000.56
24_A406_R1.4990.56
85_F254_S1.4930.56
25_L30_V1.4840.55
381_L384_I1.4840.55
370_V373_A1.4830.55
88_R106_E1.4780.55
79_I419_N1.4610.54
16_I317_V1.4580.54
368_A374_L1.4550.54
95_F349_K1.4540.54
238_K421_I1.4520.54
236_E267_L1.4450.53
45_F313_M1.4430.53
19_L76_N1.4430.53
249_F437_F1.4390.53
333_E371_S1.4380.53
199_T207_I1.4280.52
163_L289_L1.4280.52
151_L414_I1.4260.52
208_F359_S1.4150.52
198_L207_I1.4080.51
306_S310_L1.4020.51
377_I410_I1.4000.51
168_L440_I1.3930.50
86_L226_L1.3890.50
28_S259_I1.3870.50
186_N190_Y1.3850.50
202_I210_V1.3830.50
166_L230_L1.3830.50
204_L390_V1.3750.50
254_S346_R1.3720.49
119_A212_Y1.3570.49
416_S452_V1.3460.48
320_E323_S1.3440.48
422_A428_G1.3030.46
141_F351_Q1.2940.45
300_R447_I1.2890.45
71_T197_V1.2870.45
115_N341_S1.2840.45
43_D182_Y1.2830.45
140_T169_A1.2810.45
88_R286_L1.2800.45
55_I439_G1.2780.44
88_R335_L1.2710.44
120_R166_L1.2690.44
211_I226_L1.2670.44
12_D81_F1.2650.44
93_V404_I1.2630.44
208_F211_I1.2610.44
119_A348_R1.2600.43
399_V405_S1.2600.43
36_I39_L1.2600.43
88_R332_G1.2580.43
65_K137_S1.2440.43
249_F361_Y1.2410.42
201_T212_Y1.2320.42
55_I445_S1.2320.42
45_F149_L1.2280.42
163_L200_F1.2260.42
83_K318_L1.2180.41
66_F138_S1.2140.41
55_I444_L1.2090.41
22_M210_V1.2060.41
206_I348_R1.2050.41
359_S434_S1.2040.41
19_L226_L1.2030.41
176_L210_V1.2010.40
138_S349_K1.1990.40
115_N445_S1.1980.40
135_L149_L1.1910.40
176_L181_L1.1890.40
82_L413_L1.1890.40
165_I410_I1.1870.40
366_A427_Y1.1870.40
140_T312_S1.1840.40
25_L312_S1.1820.39
55_I386_S1.1810.39
26_F122_I1.1780.39
157_T289_L1.1750.39
186_N193_I1.1730.39
231_R317_V1.1730.39
370_V374_L1.1680.39
249_F310_L1.1570.38
28_S227_G1.1570.38
28_S257_Y1.1540.38
80_R168_L1.1500.38
169_A295_K1.1480.38
271_L351_Q1.1460.38
145_D150_S1.1350.37
202_I205_S1.1320.37
7_A298_I1.1240.37
381_L393_V1.1220.36
242_I276_G1.1220.36
16_I107_I1.1210.36
54_K94_T1.1190.36
248_L449_Y1.1180.36
31_P131_I1.1170.36
288_R301_L1.1170.36
225_L451_I1.1170.36
95_F260_V1.1130.36
103_L290_N1.1130.36
145_D368_A1.1130.36
378_V383_N1.1110.36
36_I265_E1.1100.36
62_Y254_S1.1080.36
321_T331_I1.1030.36
310_L346_R1.1000.35
362_A428_G1.0960.35
384_I400_N1.0930.35
89_L183_R1.0920.35
131_I179_Y1.0850.35
45_F349_K1.0850.35
334_I349_K1.0820.35
46_E51_V1.0740.34
31_P68_S1.0730.34
131_I152_I1.0720.34
308_S438_I1.0710.34
40_S216_I1.0660.34
23_L331_I1.0660.34
22_M49_T1.0640.34
301_L412_L1.0640.34
135_L296_E1.0600.33
225_L442_I1.0520.33
200_F450_H1.0510.33
19_L47_P1.0500.33
57_N232_Y1.0490.33
305_E437_F1.0470.33
378_V450_H1.0470.33
103_L181_L1.0460.33
200_F279_R1.0430.33
132_Y278_V1.0420.33
57_N62_Y1.0420.33
108_D390_V1.0410.33
114_Y345_I1.0400.33
123_E408_F1.0370.32
246_F294_D1.0370.32
102_F168_L1.0360.32
21_F404_I1.0330.32
207_I414_I1.0310.32
22_M48_Y1.0270.32
141_F148_I1.0270.32
212_Y226_L1.0240.32
103_L337_K1.0240.32
51_V436_Y1.0230.32
11_V51_V1.0220.32
294_D398_E1.0200.32
82_L355_A1.0200.32
18_M49_T1.0160.31
378_V397_S1.0130.31
52_F289_L1.0100.31
367_S429_K1.0060.31
270_V370_V1.0060.31
249_F274_D1.0040.31
420_G424_T1.0040.31
189_R192_V1.0040.31
47_P50_K1.0020.31
83_K351_Q0.9990.31
143_V152_I0.9940.30
31_P322_I0.9930.30
129_L137_S0.9930.30
108_D193_I0.9890.30
22_M82_L0.9890.30
164_T448_S0.9880.30
13_S117_Y0.9870.30
163_L413_L0.9860.30
276_G368_A0.9860.30
76_N297_K0.9830.30
138_S334_I0.9830.30
157_T200_F0.9800.30
140_T321_T0.9790.30
18_M48_Y0.9750.30
233_R237_N0.9740.30
147_T289_L0.9700.29
40_S237_N0.9680.29
199_T230_L0.9660.29
289_L401_I0.9640.29
186_N189_R0.9630.29
148_I407_I0.9600.29
416_S420_G0.9580.29
251_R366_A0.9570.29
183_R298_I0.9540.29
94_T397_S0.9530.29
251_R340_D0.9530.29
217_V443_I0.9530.29
418_A426_A0.9510.29
108_D360_I0.9500.29
147_T419_N0.9430.28
138_S141_F0.9410.28
129_L427_Y0.9340.28
230_L244_R0.9310.28
95_F262_N0.9310.28
88_R325_G0.9280.28
260_V321_T0.9260.27
207_I265_E0.9240.27
101_E447_I0.9210.27
65_K291_F0.9200.27
32_P138_S0.9180.27
348_R411_I0.9180.27
15_Y179_Y0.9130.27
35_V331_I0.9120.27
30_V171_L0.9120.27
359_S426_A0.9100.27
217_V230_L0.9050.27
12_D300_R0.9040.27
141_F247_L0.9020.26
29_G169_A0.9020.26
37_L171_L0.8930.26
308_S412_L0.8910.26
200_F209_S0.8890.26
226_L268_M0.8880.26
10_E207_I0.8880.26
85_F202_I0.8840.26
125_M179_Y0.8840.26
87_I141_F0.8820.26
282_I346_R0.8800.26
65_K169_A0.8790.26
40_S207_I0.8790.26
138_S366_A0.8780.26
239_I307_G0.8770.25
210_V447_I0.8760.25
216_I403_I0.8740.25
411_I422_A0.8740.25
74_I435_L0.8660.25
26_F409_L0.8650.25
229_G310_L0.8620.25
263_L266_S0.8610.25
204_L210_V0.8580.25
285_S330_I0.8570.25
22_M311_V0.8560.25
278_V302_I0.8560.25
10_E179_Y0.8540.25
136_N362_A0.8530.25
272_R441_L0.8530.25
198_L451_I0.8530.25
197_V211_I0.8530.25
10_E272_R0.8510.24
30_V282_I0.8500.24
8_K82_L0.8480.24
85_F103_L0.8450.24
440_I443_I0.8390.24
383_N447_I0.8390.24
231_R323_S0.8380.24
55_I98_D0.8380.24
307_G381_L0.8370.24
176_L419_N0.8370.24
52_F240_N0.8370.24
38_H176_L0.8350.24
36_I55_I0.8340.24
212_Y451_I0.8340.24
208_F231_R0.8290.24
167_S408_F0.8230.23
420_G435_L0.8220.23
69_A122_I0.8200.23
204_L209_S0.8190.23
82_L309_I0.8160.23
332_G415_L0.8160.23
136_N264_K0.8150.23
145_D345_I0.8150.23
151_L282_I0.8140.23
190_Y193_I0.8140.23
313_M415_L0.8120.23
28_S302_I0.8110.23
178_M414_I0.8110.23
21_F260_V0.8030.23
362_A427_Y0.8020.23
158_T447_I0.8020.23
65_K325_G0.7980.22
255_R328_A0.7960.22
246_F321_T0.7950.22
99_M429_K0.7940.22
220_G308_S0.7940.22
112_S411_I0.7900.22
167_S200_F0.7870.22
89_L360_I0.7820.22
258_A384_I0.7810.22
309_I318_L0.7810.22
101_E386_S0.7810.22
188_I192_V0.7810.22
28_S344_N0.7790.22
386_S445_S0.7780.22
45_F175_T0.7780.22
140_T324_M0.7780.22
114_Y349_K0.7770.22
86_L170_L0.7750.22
15_Y284_R0.7750.22
221_T280_P0.7750.22
369_G413_L0.7750.22
88_R97_D0.7740.22
203_S206_I0.7740.22
132_Y437_F0.7710.21
171_L174_L0.7700.21
198_L211_I0.7690.21
218_L397_S0.7680.21
199_T206_I0.7680.21
25_L347_S0.7680.21
173_N447_I0.7660.21
144_A261_S0.7650.21
208_F212_Y0.7640.21
306_S356_F0.7610.21
86_L98_D0.7580.21
53_K108_D0.7560.21
17_F20_A0.7560.21
119_A417_F0.7530.21
189_R443_I0.7520.21
282_I289_L0.7520.21
228_I432_Y0.7510.21
299_F424_T0.7510.21
119_A262_N0.7500.21
80_R444_L0.7490.21
333_E447_I0.7440.21
428_G436_Y0.7410.20
34_I262_N0.7400.20
75_K207_I0.7390.20
234_L448_S0.7390.20
78_N437_F0.7380.20
377_I439_G0.7360.20
4_I16_I0.7350.20
41_R209_S0.7340.20
88_R446_S0.7330.20
122_I363_L0.7320.20
94_T120_R0.7320.20
29_G353_G0.7320.20
12_D83_K0.7320.20
139_L266_S0.7310.20
423_I449_Y0.7290.20
335_L410_I0.7290.20
131_I146_I0.7290.20
400_N405_S0.7280.20
316_K408_F0.7270.20
120_R266_S0.7270.20
173_N205_S0.7260.20
129_L301_L0.7240.20
400_N437_F0.7220.20
243_E250_I0.7200.20
239_I243_E0.7190.20
21_F24_A0.7190.20
80_R219_M0.7190.20
85_F96_G0.7180.20
225_L268_M0.7180.20
22_M50_K0.7180.20
360_I363_L0.7170.20
413_L442_I0.7170.20
79_I222_G0.7160.20
133_A136_N0.7150.20
162_Q167_S0.7130.19
200_F204_L0.7110.19
298_I365_T0.7090.19
128_F416_S0.7090.19
330_I418_A0.7090.19
24_A95_F0.7060.19
90_S97_D0.7050.19
138_S338_I0.7030.19
243_E307_G0.7010.19
16_I62_Y0.6970.19
40_S133_A0.6970.19
305_E356_F0.6950.19
268_M381_L0.6950.19
22_M37_L0.6940.19
144_A282_I0.6940.19
79_I130_T0.6930.19
47_P381_L0.6930.19
179_Y441_L0.6900.19
296_E451_I0.6900.19
272_R402_D0.6890.19
225_L232_Y0.6870.19
122_I353_G0.6870.19
49_T419_N0.6840.19
86_L90_S0.6840.19
407_I451_I0.6820.18
164_T407_I0.6820.18
282_I365_T0.6820.18
287_N347_S0.6810.18
200_F270_V0.6770.18
201_T209_S0.6770.18
133_A137_S0.6750.18
292_G440_I0.6750.18
129_L321_T0.6750.18
136_N139_L0.6740.18
29_G63_R0.6740.18
170_L425_L0.6730.18
82_L338_I0.6730.18
41_R74_I0.6720.18
116_A284_R0.6720.18
96_G349_K0.6700.18
112_S414_I0.6700.18
70_I440_I0.6700.18
147_T374_L0.6680.18
168_L325_G0.6680.18
154_S328_A0.6680.18
299_F315_S0.6680.18
286_L371_S0.6660.18
202_I279_R0.6650.18
200_F211_I0.6650.18
21_F320_E0.6620.18
164_T182_Y0.6620.18
86_L93_V0.6600.18
439_G443_I0.6570.18
167_S365_T0.6550.18
202_I277_D0.6540.18
323_S374_L0.6510.17
202_I208_F0.6500.17
346_R363_L0.6480.17
62_Y428_G0.6470.17
135_L418_A0.6450.17
68_S430_S0.6440.17
166_L200_F0.6430.17
325_G335_L0.6400.17
31_P222_G0.6390.17
56_R71_T0.6340.17
113_E359_S0.6340.17
199_T202_I0.6310.17
123_E126_N0.6290.17
161_I359_S0.6280.17
78_N279_R0.6270.17
299_F317_V0.6270.17
208_F280_P0.6270.17
41_R280_P0.6260.17
57_N166_L0.6260.17
200_F391_S0.6250.17
27_S332_G0.6240.17
164_T337_K0.6230.17
155_G237_N0.6230.17
74_I166_L0.6210.17
216_I330_I0.6190.17
287_N319_Y0.6190.17
141_F346_R0.6180.16
20_A246_F0.6170.16
209_S230_L0.6170.16
95_F144_A0.6160.16
198_L386_S0.6150.16
375_I378_V0.6150.16
36_I286_L0.6140.16
302_I311_V0.6140.16
329_M360_I0.6130.16
288_R362_A0.6130.16
168_L174_L0.6120.16
304_D439_G0.6120.16
272_R280_P0.6110.16
122_I132_Y0.6110.16
176_L294_D0.6090.16
138_S328_A0.6080.16
246_F311_V0.6080.16
82_L374_L0.6060.16
134_T285_S0.6050.16
160_I188_I0.6040.16
255_R258_A0.6040.16
204_L388_Q0.6020.16
82_L412_L0.6020.16
87_I259_I0.6000.16
19_L385_F0.6000.16
216_I392_T0.6000.16
416_S442_I0.5990.16
210_V248_L0.5990.16
98_D206_I0.5990.16
282_I397_S0.5960.16
88_R358_T0.5950.16
45_F48_Y0.5950.16
140_T257_Y0.5940.16
219_M443_I0.5940.16
211_I241_R0.5930.16
167_S402_D0.5890.16
154_S209_S0.5880.16
84_E361_Y0.5880.16
176_L431_L0.5880.16
28_S66_F0.5870.16
153_Y162_Q0.5870.16
31_P155_G0.5860.16
192_V441_L0.5850.16
162_Q207_I0.5850.16
208_F300_R0.5850.16
25_L28_S0.5840.16
18_M55_I0.5840.16
22_M41_R0.5840.16
106_E428_G0.5820.15
375_I447_I0.5810.15
228_I435_L0.5800.15
36_I369_G0.5800.15
402_D448_S0.5770.15
220_G437_F0.5760.15
11_V130_T0.5750.15
119_A174_L0.5750.15
243_E346_R0.5740.15
27_S246_F0.5730.15
11_V46_E0.5730.15
142_L388_Q0.5710.15
41_R75_K0.5700.15
68_S318_L0.5690.15
119_A425_L0.5690.15
202_I212_Y0.5660.15
302_I308_S0.5660.15
130_T420_G0.5650.15
254_S308_S0.5620.15
74_I174_L0.5620.15
200_F212_Y0.5610.15
190_Y206_I0.5610.15
63_R414_I0.5590.15
84_E102_F0.5590.15
229_G325_G0.5580.15
85_F181_L0.5570.15
359_S406_R0.5540.15
249_F426_A0.5540.15
252_Y325_G0.5490.15
197_V200_F0.5490.15
444_L448_S0.5480.15
5_F41_R0.5470.15
170_L175_T0.5460.15
106_E229_G0.5460.15
49_T388_Q0.5450.14
69_A92_A0.5450.14
88_R299_F0.5440.14
140_T339_G0.5440.14
73_S76_N0.5410.14
151_L162_Q0.5400.14
27_S133_A0.5390.14
68_S377_I0.5390.14
63_R92_A0.5390.14
170_L272_R0.5380.14
34_I399_V0.5380.14
257_Y260_V0.5380.14
410_I415_L0.5350.14
385_F388_Q0.5350.14
41_R198_L0.5350.14
23_L28_S0.5340.14
209_S213_T0.5340.14
169_A332_G0.5340.14
20_A270_V0.5340.14
206_I283_R0.5340.14
65_K339_G0.5340.14
160_I347_S0.5320.14
289_L346_R0.5320.14
79_I434_S0.5310.14
240_N383_N0.5310.14
4_I321_T0.5310.14
132_Y360_I0.5310.14
58_L250_I0.5310.14
28_S84_E0.5310.14
58_L62_Y0.5310.14
358_T438_I0.5300.14
200_F207_I0.5280.14
50_K213_T0.5280.14
10_E244_R0.5260.14
9_N270_V0.5260.14
298_I359_S0.5250.14
65_K377_I0.5250.14
78_N298_I0.5230.14
246_F319_Y0.5210.14
53_K440_I0.5210.14
216_I237_N0.5200.14
121_L136_N0.5200.14
75_K391_S0.5190.14
203_S212_Y0.5190.14
251_R286_L0.5190.14
233_R436_Y0.5170.14
85_F128_F0.5170.14
201_T391_S0.5140.14
179_Y206_I0.5140.14
151_L418_A0.5130.14
124_S370_V0.5130.14
5_F8_K0.5130.14
13_S254_S0.5130.14
36_I115_N0.5120.14
258_A278_V0.5120.14
277_D447_I0.5110.14
283_R390_V0.5090.14
130_T278_V0.5080.14
130_T222_G0.5080.14
30_V120_R0.5060.13
111_L162_Q0.5060.13
80_R417_F0.5060.13
205_S210_V0.5050.13
212_Y440_I0.5040.13
226_L381_L0.5040.13
15_Y162_Q0.5040.13
230_L421_I0.5030.13
206_I369_G0.5030.13
29_G424_T0.5030.13
202_I417_F0.5020.13
166_L177_V0.5020.13
132_Y434_S0.5020.13
83_K452_V0.5020.13
12_D331_I0.5010.13
32_P179_Y0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c1qA 2 0.2537 98.2 0.913 Contact Map
2whnA 1 0.2304 98.2 0.915 Contact Map
4hhxA 1 0.2114 98.1 0.917 Contact Map
2j91A 4 0.2389 33.3 0.969 Contact Map
4ev6A 3 0.3805 15.7 0.974 Contact Map
4i0uA 4 0.3763 13.3 0.975 Contact Map
1yisA 4 0.1543 12.1 0.975 Contact Map
2lv7A 1 0.1987 9.1 0.977 Contact Map
3fx7A 2 0.1691 8.9 0.977 Contact Map
1sedA 3 0.1268 6.3 0.978 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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