GREMLIN Database
Q97WB7 - Flagella-related protein I, putative (FlaI)
UniProt: Q97WB7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 513 (403)
Sequences: 3386 (2291)
Seq/√Len: 114.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
455_R475_E5.1601.00
399_K431_D5.1481.00
247_Y275_I4.4601.00
405_R432_P4.0301.00
218_N284_K3.9501.00
250_M388_I3.8841.00
363_N366_T3.7171.00
176_I219_L3.6201.00
461_R471_N3.5971.00
461_R466_L3.2711.00
248_I278_F3.1631.00
404_R429_T3.1511.00
399_K494_Q3.0181.00
286_V324_A3.0021.00
402_L436_K2.9221.00
283_L331_Y2.8351.00
471_N475_E2.6721.00
259_F357_A2.6541.00
405_R430_Y2.6021.00
202_S225_S2.5971.00
288_I320_L2.5951.00
473_R482_S2.5701.00
390_L451_K2.5281.00
192_P313_G2.4821.00
261_C359_F2.4421.00
398_K446_Y2.4311.00
457_G475_E2.4081.00
399_K404_R2.3731.00
446_Y492_W2.3521.00
337_I345_A2.3201.00
484_K498_A2.3181.00
214_R292_P2.3111.00
434_E437_I2.2971.00
183_T208_Y2.2881.00
244_L248_I2.2881.00
150_I172_L2.2571.00
206_F221_V2.2451.00
471_N474_A2.2291.00
251_M275_I2.1751.00
218_N300_N2.1751.00
431_D494_Q2.1681.00
249_W453_A2.1561.00
279_I331_Y2.1231.00
138_F443_G2.1191.00
454_I462_N2.0951.00
460_R464_G2.0951.00
458_I468_D2.0941.00
130_L175_L2.0601.00
363_N469_E2.0371.00
455_R471_N2.0331.00
305_V312_E2.0011.00
410_D413_I1.9881.00
243_L449_E1.9791.00
162_T165_L1.9651.00
211_D302_V1.9411.00
478_K486_F1.9331.00
483_K487_N1.9021.00
242_P478_K1.8881.00
241_S245_A1.8811.00
486_F490_E1.8651.00
159_P500_Q1.8391.00
365_R452_V1.8131.00
185_R210_I1.8091.00
288_I324_A1.8041.00
210_I219_L1.7991.00
407_V430_Y1.7941.00
206_F223_K1.7731.00
209_G327_Q1.7621.00
149_H165_L1.7381.00
240_L243_L1.6781.00
452_V477_L1.6771.00
305_V313_G1.6581.00
243_L451_K1.6551.00
485_I489_F1.6451.00
488_Y498_A1.6331.00
481_L502_G1.6161.00
372_T382_Y1.6141.00
470_L474_A1.6081.00
407_V428_F1.5971.00
402_L443_G1.5881.00
151_Y162_T1.5781.00
368_V386_L1.5731.00
280_P285_I1.5731.00
213_S300_N1.5681.00
407_V413_I1.5361.00
457_G474_A1.5151.00
243_L483_K1.5081.00
144_I150_I1.5021.00
399_K432_P1.4971.00
320_L324_A1.4971.00
233_Q236_S1.4941.00
258_L354_S1.4801.00
446_Y487_N1.4651.00
264_T329_P1.4441.00
472_L476_F1.4421.00
245_A249_W1.4421.00
467_Y470_L1.4311.00
433_T437_I1.4281.00
302_V324_A1.3951.00
365_R469_E1.3691.00
239_T271_T1.3541.00
100_L103_I1.3521.00
400_G403_I1.3411.00
253_D387_N1.3281.00
409_V414_D1.3271.00
321_L344_V1.3201.00
218_N286_V1.3081.00
250_M451_K1.3041.00
204_V223_K1.3031.00
162_T281_P1.2910.99
400_G434_E1.2900.99
249_W253_D1.2810.99
400_G437_I1.2790.99
159_P396_Y1.2780.99
154_H163_S1.2730.99
365_R468_D1.2710.99
456_R459_E1.2710.99
343_N347_Q1.2620.99
252_L278_F1.2620.99
258_L388_I1.2600.99
487_N492_W1.2590.99
347_Q373_G1.2570.99
279_I356_M1.2510.99
401_N404_R1.2490.99
242_P246_A1.2480.99
246_A453_A1.2400.99
472_L477_L1.2370.99
243_L246_A1.2360.99
235_I244_L1.2330.99
99_V104_L1.2220.99
306_T313_G1.2080.99
469_E473_R1.1880.99
316_K319_D1.1830.99
391_F480_L1.1820.99
169_E172_L1.1770.99
403_I434_E1.1720.99
239_T449_E1.1700.99
488_Y495_I1.1670.99
350_Q381_S1.1650.99
139_I156_V1.1640.99
430_Y496_L1.1600.99
389_A452_V1.1590.99
224_F294_L1.1590.99
403_I437_I1.1560.99
179_L208_Y1.1510.99
271_T392_Q1.1410.99
473_R477_L1.1270.99
409_V413_I1.1240.99
332_I348_A1.1180.98
377_E380_K1.1120.98
264_T353_H1.1080.98
340_K343_N1.1050.98
234_L274_A1.1040.98
359_F367_L1.0960.98
399_K429_T1.0920.98
464_G467_Y1.0880.98
198_L206_F1.0860.98
218_N327_Q1.0830.98
468_D472_L1.0790.98
259_F337_I1.0660.98
239_T247_Y1.0630.98
192_P315_V1.0610.98
396_Y497_R1.0530.98
428_F488_Y1.0480.98
429_T432_P1.0450.98
138_F156_V1.0310.97
365_R477_L1.0260.97
145_P153_V1.0250.97
326_R338_R1.0240.97
347_Q350_Q1.0240.97
271_T390_L1.0220.97
428_F431_D1.0170.97
96_M99_V1.0160.97
379_P465_I1.0130.97
479_I482_S1.0120.97
203_R226_K1.0110.97
448_I484_K1.0060.97
386_L389_A1.0060.97
478_K482_S1.0020.97
240_L486_F1.0010.97
318_F341_E0.9970.97
419_T422_V0.9970.97
159_P282_N0.9970.97
342_G376_I0.9910.97
99_V103_I0.9850.97
288_I302_V0.9830.97
342_G371_L0.9760.96
125_L128_G0.9760.96
486_F489_F0.9720.96
473_R479_I0.9660.96
91_E95_L0.9620.96
409_V428_F0.9610.96
166_I175_L0.9570.96
337_I357_A0.9510.96
260_V271_T0.9510.96
406_V427_A0.9510.96
91_E94_I0.9490.96
329_P353_H0.9440.96
325_L348_A0.9440.96
101_D104_L0.9430.96
448_I502_G0.9420.96
336_E360_H0.9410.96
97_R101_D0.9400.96
96_M104_L0.9390.96
395_L493_N0.9360.95
465_I474_A0.9360.95
442_R493_N0.9350.95
286_V302_V0.9330.95
485_I495_I0.9320.95
269_T294_L0.9230.95
422_V425_I0.9230.95
243_L390_L0.9170.95
234_L248_I0.9100.95
453_A477_L0.9070.95
92_K100_L0.9040.95
134_I206_F0.9030.95
251_M258_L0.9030.95
235_I248_I0.9030.95
149_H297_P0.9010.94
260_V390_L0.9000.94
346_F376_I0.8970.94
268_K336_E0.8950.94
288_I304_E0.8910.94
130_L179_L0.8910.94
240_L490_E0.8900.94
182_K198_L0.8890.94
468_D476_F0.8890.94
457_G471_N0.8870.94
442_R494_Q0.8870.94
487_N490_E0.8840.94
98_R104_L0.8840.94
94_I98_R0.8830.94
452_V458_I0.8820.94
255_G363_N0.8820.94
93_E97_R0.8820.94
485_I488_Y0.8800.94
284_K327_Q0.8770.94
240_L487_N0.8750.94
367_L389_A0.8680.93
257_N355_V0.8660.93
93_E99_V0.8650.93
239_T447_L0.8650.93
96_M100_L0.8570.93
408_E426_P0.8560.93
237_F449_E0.8550.93
372_T465_I0.8540.93
174_N181_E0.8510.93
421_D424_Y0.8500.93
302_V320_L0.8490.93
319_D323_A0.8480.92
250_M387_N0.8450.92
483_K486_F0.8440.92
324_A332_I0.8430.92
418_V421_D0.8410.92
383_I463_I0.8390.92
382_Y386_L0.8360.92
268_K360_H0.8340.92
229_I233_Q0.8330.92
457_G460_R0.8300.92
280_P298_H0.8270.92
257_N386_L0.8270.92
263_E393_T0.8250.91
91_E100_L0.8210.91
452_V472_L0.8160.91
484_K493_N0.8150.91
96_M103_I0.8140.91
418_V422_V0.8120.91
492_W498_A0.8120.91
358_T361_A0.8070.90
284_K300_N0.8060.90
495_I499_R0.8050.90
261_C367_L0.8020.90
405_R431_D0.8000.90
240_L483_K0.7990.90
95_L100_L0.7970.90
458_I472_L0.7950.90
93_E103_I0.7950.90
314_S319_D0.7940.90
110_S113_K0.7940.90
222_R360_H0.7930.90
156_V161_R0.7880.89
292_P303_A0.7880.89
129_I133_L0.7840.89
133_L152_I0.7840.89
461_R467_Y0.7840.89
337_I342_G0.7810.89
418_V424_Y0.7810.89
92_K103_I0.7800.89
127_S131_E0.7790.89
129_I175_L0.7780.89
306_T315_V0.7770.89
420_N423_V0.7750.89
418_V423_V0.7740.89
273_N296_V0.7740.89
454_I458_I0.7730.89
180_S217_S0.7730.89
494_Q497_R0.7730.89
103_I106_K0.7720.88
209_G323_A0.7700.88
92_K95_L0.7700.88
137_P161_R0.7700.88
91_E96_M0.7650.88
261_C361_A0.7650.88
202_S227_I0.7640.88
241_S244_L0.7600.88
424_Y427_A0.7600.88
97_R103_I0.7590.88
489_F492_W0.7590.88
95_L99_V0.7580.88
186_P312_E0.7550.87
434_E438_I0.7530.87
407_V410_D0.7530.87
272_L333_L0.7520.87
411_E414_D0.7520.87
156_V163_S0.7510.87
91_E103_I0.7480.87
426_P489_F0.7480.87
95_L103_I0.7470.87
179_L221_V0.7470.87
457_G461_R0.7450.87
134_I142_I0.7450.87
114_E117_I0.7450.87
316_K341_E0.7440.87
222_R336_E0.7430.86
277_A280_P0.7420.86
346_F381_S0.7400.86
185_R209_G0.7380.86
454_I459_E0.7370.86
246_A249_W0.7360.86
172_L176_I0.7360.86
208_Y221_V0.7340.86
148_G215_R0.7330.86
469_E479_I0.7310.86
415_I418_V0.7280.85
484_K487_N0.7250.85
245_A252_L0.7250.85
363_N480_L0.7250.85
415_I419_T0.7240.85
322_K341_E0.7230.85
255_G387_N0.7220.85
133_L142_I0.7210.85
420_N424_Y0.7200.85
302_V315_V0.7180.85
92_K101_D0.7160.84
264_T351_T0.7130.84
199_P203_R0.7120.84
222_R268_K0.7120.84
234_L244_L0.7100.84
247_Y258_L0.7050.83
467_Y471_N0.7010.83
93_E96_M0.6990.83
147_L151_Y0.6940.83
452_V468_D0.6920.82
93_E101_D0.6910.82
137_P438_I0.6900.82
293_E360_H0.6890.82
100_L104_L0.6870.82
245_A412_I0.6860.82
178_S182_K0.6850.82
97_R102_K0.6850.82
482_S486_F0.6850.82
106_K109_I0.6840.82
91_E99_V0.6840.82
93_E100_L0.6830.82
226_K294_L0.6820.81
326_R360_H0.6810.81
401_N436_K0.6800.81
94_I99_V0.6800.81
275_I288_I0.6780.81
247_Y451_K0.6780.81
469_E480_L0.6760.81
99_V102_K0.6750.81
183_T198_L0.6750.81
419_T423_V0.6740.81
94_I97_R0.6730.81
197_S205_N0.6720.80
92_K97_R0.6700.80
131_E135_R0.6700.80
329_P370_R0.6700.80
199_P206_F0.6680.80
119_H122_R0.6680.80
361_A364_I0.6660.80
383_I387_N0.6660.80
270_T294_L0.6660.80
181_E284_K0.6650.80
204_V225_S0.6640.80
323_A327_Q0.6640.80
306_T316_K0.6640.80
133_L164_L0.6630.80
136_D200_D0.6620.79
269_T461_R0.6610.79
122_R325_L0.6610.79
286_V300_N0.6610.79
350_Q385_N0.6580.79
118_Y136_D0.6570.79
195_D209_G0.6550.79
255_G270_T0.6550.79
121_V413_I0.6530.79
346_F350_Q0.6530.79
264_T326_R0.6510.78
98_R105_T0.6500.78
403_I433_T0.6460.78
398_K492_W0.6440.78
474_A490_E0.6420.77
421_D482_S0.6420.77
353_H370_R0.6420.77
103_I107_I0.6390.77
261_C391_F0.6390.77
192_P319_D0.6390.77
242_P245_A0.6370.77
211_D324_A0.6370.77
482_S485_I0.6360.77
324_A334_V0.6360.77
127_S178_S0.6360.77
293_E336_E0.6350.77
400_G433_T0.6350.77
417_P423_V0.6330.76
399_K405_R0.6330.76
260_V447_L0.6320.76
222_R293_E0.6320.76
203_R435_D0.6300.76
450_N477_L0.6290.76
473_R476_F0.6290.76
269_T284_K0.6280.76
230_S233_Q0.6270.76
396_Y442_R0.6260.76
93_E104_L0.6260.76
140_E220_T0.6260.76
145_P190_N0.6260.76
420_N427_A0.6240.75
98_R103_I0.6230.75
269_T296_V0.6230.75
493_N497_R0.6230.75
242_P486_F0.6210.75
315_V323_A0.6190.75
326_R336_E0.6170.75
95_L98_R0.6160.74
205_N226_K0.6120.74
277_A296_V0.6110.74
459_E463_I0.6110.74
343_N377_E0.6080.74
499_R502_G0.6080.74
257_N346_F0.6070.73
225_S273_N0.6060.73
249_W252_L0.6050.73
406_V429_T0.6020.73
101_D107_I0.6010.73
115_Y118_Y0.6010.73
214_R295_T0.6010.73
120_F123_D0.5990.72
96_M102_K0.5990.72
276_T333_L0.5980.72
229_I274_A0.5980.72
209_G220_T0.5970.72
281_P464_G0.5970.72
233_Q278_F0.5960.72
100_L107_I0.5960.72
415_I427_A0.5960.72
211_D327_Q0.5960.72
257_N388_I0.5950.72
251_M356_M0.5940.72
398_K402_L0.5940.72
458_I471_N0.5930.72
181_E187_V0.5920.72
269_T274_A0.5910.71
296_V299_S0.5900.71
315_V320_L0.5890.71
99_V107_I0.5890.71
97_R104_L0.5890.71
421_D426_P0.5880.71
473_R478_K0.5870.71
108_R111_V0.5870.71
423_V427_A0.5860.71
254_E362_A0.5860.71
448_I501_F0.5860.71
468_D471_N0.5860.71
288_I367_L0.5850.71
159_P501_F0.5830.70
92_K96_M0.5820.70
485_I498_A0.5810.70
144_I221_V0.5810.70
114_E121_V0.5800.70
290_D303_A0.5800.70
100_L105_T0.5790.70
228_P282_N0.5790.70
143_S328_R0.5770.70
427_A430_Y0.5770.70
423_V426_P0.5770.70
93_E98_R0.5760.69
205_N327_Q0.5760.69
406_V426_P0.5750.69
338_R360_H0.5750.69
468_D477_L0.5740.69
218_N302_V0.5710.69
421_D425_I0.5710.69
419_T426_P0.5700.69
107_I113_K0.5670.68
332_I353_H0.5670.68
92_K99_V0.5670.68
428_F489_F0.5670.68
279_I285_I0.5660.68
149_H162_T0.5650.68
417_P420_N0.5650.68
235_I241_S0.5650.68
453_A475_E0.5640.68
406_V409_V0.5640.68
205_N294_L0.5620.68
470_L473_R0.5620.68
104_L108_R0.5600.67
345_A355_V0.5600.67
106_K110_S0.5590.67
186_P407_V0.5590.67
452_V479_I0.5580.67
239_T487_N0.5570.67
372_T379_P0.5570.67
133_L144_I0.5560.67
474_A478_K0.5550.67
272_L356_M0.5550.67
472_L475_E0.5530.66
418_V426_P0.5520.66
107_I110_S0.5520.66
134_I198_L0.5520.66
257_N347_Q0.5510.66
150_I175_L0.5510.66
366_T369_Q0.5490.66
151_Y165_L0.5480.66
201_G473_R0.5470.66
106_K113_K0.5470.66
321_L324_A0.5470.66
372_T376_I0.5450.65
116_A119_H0.5450.65
98_R101_D0.5430.65
279_I283_L0.5430.65
460_R470_L0.5430.65
372_T380_K0.5420.65
498_A502_G0.5410.65
408_E421_D0.5400.65
383_I462_N0.5380.64
413_I496_L0.5380.64
431_D434_E0.5370.64
411_E415_I0.5360.64
387_N459_E0.5340.64
414_D426_P0.5330.64
243_L478_K0.5330.64
402_L495_I0.5320.63
257_N387_N0.5320.63
253_D456_R0.5320.63
136_D164_L0.5300.63
266_S392_Q0.5290.63
204_V334_V0.5290.63
193_I212_I0.5290.63
101_D105_T0.5280.63
95_L104_L0.5280.63
451_K454_I0.5280.63
207_V212_I0.5280.63
419_T424_Y0.5270.63
254_E359_F0.5270.63
442_R496_L0.5260.63
170_E228_P0.5250.62
117_I121_V0.5250.62
319_D332_I0.5250.62
413_I417_P0.5250.62
143_S291_T0.5240.62
175_L490_E0.5240.62
147_L218_N0.5230.62
276_T299_S0.5230.62
118_Y190_N0.5230.62
300_N327_Q0.5210.62
411_E423_V0.5210.62
128_G132_P0.5210.62
185_R219_L0.5200.62
368_V462_N0.5180.61
460_R466_L0.5180.61
326_R335_G0.5180.61
334_V344_V0.5170.61
481_L498_A0.5160.61
453_A456_R0.5160.61
313_G316_K0.5160.61
91_E101_D0.5160.61
145_P189_H0.5150.61
179_L210_I0.5140.61
395_L448_I0.5120.60
103_I109_I0.5110.60
192_P303_A0.5110.60
335_G360_H0.5100.60
105_T112_P0.5080.60
144_I172_L0.5080.60
141_D360_H0.5070.60
243_L474_A0.5070.60
449_E487_N0.5070.60
100_L106_K0.5070.60
180_S194_I0.5060.60
268_K326_R0.5060.60
147_L166_I0.5050.59
268_K293_E0.5050.59
226_K347_Q0.5040.59
130_L269_T0.5040.59
257_N325_L0.5040.59
388_I451_K0.5040.59
187_V193_I0.5030.59
257_N349_M0.5030.59
428_F439_F0.5030.59
143_S220_T0.5020.59
292_P356_M0.5000.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4phtA 1 0.8285 100 0.41 Contact Map
4ksrA 3 0.694 100 0.431 Contact Map
2oap1 3 0.9415 100 0.444 Contact Map
4ihqA 3 0.9883 100 0.447 Contact Map
1p9rA 1 0.7193 100 0.452 Contact Map
2ewvA 3 0.6374 100 0.576 Contact Map
3jvvA 3 0.6277 100 0.587 Contact Map
2gzaA 3 0.5867 100 0.667 Contact Map
2eyuA 1 0.4522 100 0.695 Contact Map
4bloA 4 0.5088 100 0.746 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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