Q97W79 - SULSO - GREMLIN Contacts

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Q97W79 - Succinate dehydrogenase subunit A (SdhA)

UniProt:	Q97W79	Sequences: MEKIEYDAVVIGGGLAGLMSAHEIASAGFKVAVISKVFPTRSHSAAAEGGIAAYIPGNSDPNDNPDYMTYDTVKGGDYLVDQDAAELLSNKSGEIVMLLERWGALFNRQPDGRVAVRYFGGQTYPRTRFVGDKTGMALLHTLFERTSGLNVDFYNEWFSLDLVTDDKKVAGIVAMQMKTLTPFFFKTKAVVLATGGMGMLYRHTTNSYINTGDGFGIALRAGAALKDPEFVQFHPTALYPSDVLISEAARGEGAILKNIKGERFMTRYAPKKLDLAPRDIVSRAIITEIKEGRGFPGGYVGLDLTHLGEEYIKERLALAVEAAKSFAGVDAFTEPIPVRPAQHYYMGGIDVDIEGRNPDIVGLFSAGEAACVSVHGANRLGSNSLLDTLVFGQVTGRAVVQFLKSNSSNPTSNYEKEAEKVVDDAYKLVKSESGVHFGQILEKLRDTMWDYVGIYRDEGGLLNAMSEINKLRGMISNMYVTDKSKVYNTEFFNALELRNMLDLAFVIAKSALERKESRGAHYRTDYPDRDDNNWLKHTIAYLRGNTVEVTFKPVKITRWKPEPRVY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	566 (511)
Sequences:	5463 (2747)
Seq/√Len:	121.5

ECOLI - FRDA SDHA NADB
BACSU - SDHA NADB
HALSA - Q9HQ66 NADB
SULSO - Q97W79 NADB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
530_D	533_N	4.598	1.00
352_D	356_R	3.931	1.00
9_V	172_I	3.903	1.00
159_S	217_I	3.409	1.00
86_E	90_N	3.266	1.00
6_Y	32_A	3.254	1.00
80_V	85_A	3.157	1.00
262_E	267_R	3.038	1.00
258_N	262_E	3.026	1.00
452_V	508_A	2.961	1.00
88_L	374_V	2.943	1.00
258_N	288_E	2.897	1.00
458_E	515_K	2.859	1.00
472_R	505_F	2.836	1.00
20_S	191_V	2.820	1.00
451_Y	463_N	2.769	1.00
266_T	273_L	2.591	1.00
245_I	249_A	2.576	1.00
458_E	462_L	2.512	1.00
364_F	398_A	2.501	1.00
263_R	274_D	2.497	1.00
154_Y	185_F	2.475	1.00
11_I	172_I	2.461	1.00
465_M	508_A	2.436	1.00
91_K	394_V	2.415	1.00
176_Q	179_T	2.407	1.00
457_D	524_T	2.381	1.00
30_K	152_D	2.335	1.00
219_L	506_V	2.331	1.00
15_L	388_T	2.299	1.00
515_K	526_Y	2.295	1.00
443_K	467_E	2.265	1.00
32_A	154_Y	2.253	1.00
469_N	505_F	2.209	1.00
462_L	512_L	2.180	1.00
20_S	366_A	2.179	1.00
349_I	369_A	2.179	1.00
5_E	186_K	2.169	1.00
356_R	398_A	2.147	1.00
15_L	44_S	2.114	1.00
87_L	394_V	2.100	1.00
34_I	174_A	2.098	1.00
67_Y	124_Y	2.096	1.00
24_I	399_V	2.083	1.00
161_D	220_R	2.083	1.00
285_I	300_V	2.079	1.00
452_V	464_A	2.066	1.00
7_D	188_K	2.064	1.00
215_F	225_L	2.032	1.00
224_A	359_D	2.004	1.00
257_K	335_P	2.002	1.00
309_E	313_K	1.998	1.00
457_D	460_G	1.983	1.00
88_L	391_F	1.981	1.00
192_L	349_I	1.981	1.00
365_S	369_A	1.981	1.00
237_A	341_A	1.962	1.00
137_A	140_H	1.945	1.00
257_K	305_T	1.912	1.00
24_I	396_G	1.901	1.00
174_A	185_F	1.892	1.00
468_I	508_A	1.875	1.00
255_I	263_R	1.843	1.00
447_T	464_A	1.799	1.00
32_A	185_F	1.792	1.00
192_L	369_A	1.791	1.00
452_V	461_L	1.783	1.00
320_V	324_K	1.782	1.00
191_V	399_V	1.778	1.00
218_A	349_I	1.771	1.00
167_K	361_V	1.765	1.00
448_M	452_V	1.748	1.00
95_I	98_L	1.743	1.00
77_D	529_R	1.742	1.00
305_T	335_P	1.738	1.00
443_K	474_M	1.730	1.00
145_R	148_G	1.724	1.00
197_M	345_Y	1.722	1.00
82_Q	86_E	1.700	1.00
465_M	505_F	1.700	1.00
194_T	214_G	1.699	1.00
44_S	139_L	1.689	1.00
224_A	350_D	1.689	1.00
69_T	86_E	1.686	1.00
109_Q	113_R	1.676	1.00
249_A	254_A	1.676	1.00
176_Q	183_F	1.669	1.00
168_K	362_G	1.663	1.00
313_K	320_V	1.661	1.00
357_N	365_S	1.657	1.00
54_Y	65_P	1.655	1.00
354_E	398_A	1.653	1.00
465_M	509_K	1.651	1.00
76_G	80_V	1.651	1.00
200_L	507_I	1.644	1.00
84_A	353_I	1.630	1.00
220_R	499_N	1.622	1.00
41_R	46_A	1.621	1.00
444_L	468_I	1.615	1.00
287_T	291_E	1.597	1.00
146_T	153_F	1.590	1.00
447_T	467_E	1.586	1.00
218_A	223_A	1.582	1.00
225_L	228_P	1.581	1.00
8_A	24_I	1.554	1.00
351_V	370_A	1.544	1.00
458_E	523_R	1.525	1.00
435_V	474_M	1.520	1.00
169_V	190_V	1.517	1.00
313_K	332_F	1.498	1.00
157_W	176_Q	1.497	1.00
36_K	213_D	1.493	1.00
395_T	399_V	1.491	1.00
309_E	332_F	1.472	1.00
69_T	73_V	1.471	1.00
464_A	508_A	1.469	1.00
467_E	470_K	1.464	1.00
472_R	502_D	1.462	1.00
84_A	88_L	1.459	1.00
355_G	395_T	1.458	1.00
246_S	249_A	1.453	1.00
65_P	90_N	1.446	1.00
6_Y	9_V	1.441	1.00
288_E	293_R	1.441	1.00
451_Y	464_A	1.440	1.00
36_K	211_T	1.435	1.00
23_E	397_R	1.425	1.00
36_K	496_E	1.425	1.00
168_K	361_V	1.421	1.00
163_V	184_F	1.417	1.00
263_R	266_T	1.416	1.00
451_Y	460_G	1.409	1.00
187_T	190_V	1.406	1.00
65_P	69_T	1.393	1.00
100_E	114_V	1.388	1.00
283_R	522_Y	1.388	1.00
95_I	393_Q	1.382	1.00
197_M	231_V	1.381	1.00
97_M	101_R	1.380	1.00
465_M	512_L	1.375	1.00
205_T	237_A	1.368	1.00
91_K	94_E	1.367	1.00
398_A	402_F	1.367	1.00
189_A	402_F	1.367	1.00
192_L	363_L	1.360	1.00
458_E	512_L	1.359	1.00
51_I	138_L	1.353	1.00
6_Y	152_D	1.345	1.00
505_F	509_K	1.345	1.00
304_L	307_L	1.342	1.00
154_Y	157_W	1.340	1.00
198_G	342_Q	1.339	1.00
346_M	520_A	1.337	1.00
192_L	218_A	1.335	1.00
226_K	350_D	1.329	1.00
320_V	332_F	1.324	1.00
246_S	319_A	1.323	1.00
162_L	169_V	1.319	1.00
44_S	388_T	1.319	1.00
213_D	499_N	1.316	1.00
201_Y	452_V	1.308	1.00
6_Y	30_K	1.305	1.00
286_I	290_K	1.305	1.00
396_G	400_V	1.299	1.00
16_A	366_A	1.297	1.00
52_A	382_S	1.291	1.00
163_V	173_V	1.286	1.00
191_V	366_A	1.285	1.00
6_Y	154_Y	1.279	1.00
202_R	446_D	1.276	1.00
446_D	450_D	1.274	1.00
226_K	371_C	1.264	1.00
452_V	507_I	1.260	1.00
104_A	138_L	1.253	0.99
8_A	191_V	1.246	0.99
84_A	374_V	1.242	0.99
157_W	174_A	1.239	0.99
364_F	402_F	1.236	0.99
91_K	95_I	1.231	0.99
65_P	89_S	1.227	0.99
255_I	274_D	1.226	0.99
159_S	172_I	1.225	0.99
11_I	192_L	1.224	0.99
18_L	146_T	1.223	0.99
511_A	521_H	1.223	0.99
398_A	401_Q	1.223	0.99
462_L	466_S	1.222	0.99
159_S	174_A	1.222	0.99
34_I	172_I	1.217	0.99
33_V	153_F	1.211	0.99
256_L	338_V	1.210	0.99
55_I	128_R	1.201	0.99
70_Y	74_K	1.199	0.99
92_S	386_L	1.196	0.99
157_W	183_F	1.195	0.99
451_Y	467_E	1.192	0.99
66_D	86_E	1.190	0.99
268_Y	284_A	1.178	0.99
19_M	23_E	1.173	0.99
52_A	122_Q	1.172	0.99
13_G	35_S	1.169	0.99
68_M	383_N	1.160	0.99
9_V	34_I	1.145	0.99
215_F	503_L	1.142	0.99
264_F	285_I	1.139	0.99
7_D	30_K	1.136	0.99
229_E	514_R	1.135	0.99
393_Q	397_R	1.130	0.99
68_M	72_T	1.130	0.99
69_T	89_S	1.125	0.99
366_A	395_T	1.124	0.99
23_E	396_G	1.119	0.99
392_G	396_G	1.116	0.99
98_L	393_Q	1.113	0.99
23_E	393_Q	1.112	0.99
252_E	315_R	1.112	0.99
396_G	399_V	1.103	0.99
22_H	146_T	1.098	0.99
462_L	465_M	1.095	0.99
104_A	137_A	1.093	0.99
197_M	507_I	1.090	0.99
321_E	325_S	1.089	0.99
66_D	70_Y	1.087	0.99
8_A	399_V	1.086	0.99
458_E	526_Y	1.085	0.99
87_L	353_I	1.080	0.98
307_L	311_Y	1.077	0.98
351_V	365_S	1.072	0.98
312_I	320_V	1.072	0.98
441_L	445_R	1.070	0.98
220_R	502_D	1.067	0.98
223_A	363_L	1.062	0.98
374_V	391_F	1.061	0.98
215_F	345_Y	1.060	0.98
268_Y	288_E	1.055	0.98
20_S	399_V	1.054	0.98
161_D	217_I	1.050	0.98
127_T	382_S	1.045	0.98
87_L	91_K	1.043	0.98
87_L	391_F	1.038	0.98
69_T	82_Q	1.035	0.98
441_L	500_M	1.028	0.98
107_N	129_F	1.028	0.98
104_A	141_T	1.027	0.98
515_K	534_W	1.026	0.98
146_T	151_V	1.024	0.98
122_Q	382_S	1.023	0.98
136_M	140_H	1.023	0.98
18_L	33_V	1.020	0.98
20_S	395_T	1.018	0.98
266_T	274_D	1.017	0.98
133_K	318_L	1.016	0.98
165_D	170_A	1.012	0.98
309_E	333_T	1.009	0.98
447_T	451_Y	1.005	0.98
26_S	149_L	1.005	0.98
102_W	145_R	1.005	0.98
22_H	149_L	1.000	0.97
349_I	365_S	0.999	0.97
189_A	364_F	0.998	0.97
442_E	446_D	0.996	0.97
223_A	360_I	0.995	0.97
85_A	89_S	0.993	0.97
173_V	184_F	0.993	0.97
456_R	511_A	0.992	0.97
22_H	102_W	0.986	0.97
158_F	495_L	0.979	0.97
143_F	153_F	0.972	0.97
463_N	467_E	0.969	0.97
189_A	403_L	0.969	0.97
118_Y	125_P	0.969	0.97
469_N	509_K	0.968	0.97
323_A	329_V	0.966	0.97
33_V	146_T	0.965	0.97
447_T	471_L	0.960	0.97
444_L	497_L	0.959	0.97
173_V	182_P	0.959	0.97
475_I	501_L	0.958	0.97
356_R	402_F	0.956	0.97
79_L	518_R	0.955	0.97
313_K	324_K	0.954	0.97
39_P	143_F	0.953	0.97
93_G	97_M	0.953	0.97
424_D	498_R	0.953	0.97
9_V	187_T	0.951	0.97
330_D	333_T	0.950	0.97
51_I	96_V	0.948	0.97
202_R	449_W	0.948	0.97
45_A	136_M	0.947	0.96
310_E	314_E	0.944	0.96
67_Y	123_T	0.939	0.96
322_A	325_S	0.936	0.96
114_V	128_R	0.936	0.96
11_I	159_S	0.935	0.96
162_L	172_I	0.934	0.96
122_Q	127_T	0.926	0.96
105_L	137_A	0.925	0.96
351_V	372_V	0.925	0.96
21_A	151_V	0.924	0.96
510_S	538_T	0.923	0.96
329_V	334_E	0.923	0.96
23_E	26_S	0.921	0.96
158_F	496_E	0.918	0.96
23_E	98_L	0.917	0.96
255_I	306_H	0.917	0.96
257_K	303_D	0.915	0.96
223_A	359_D	0.914	0.96
164_T	169_V	0.911	0.96
25_A	150_N	0.910	0.96
263_R	273_L	0.910	0.96
72_T	383_N	0.909	0.96
125_P	252_E	0.908	0.96
267_R	291_E	0.908	0.96
323_A	331_A	0.906	0.95
467_E	471_L	0.904	0.95
308_G	311_Y	0.904	0.95
312_I	332_F	0.898	0.95
162_L	190_V	0.896	0.95
191_V	395_T	0.896	0.95
98_L	102_W	0.895	0.95
288_E	291_E	0.895	0.95
532_N	535_L	0.893	0.95
19_M	95_I	0.893	0.95
351_V	391_F	0.887	0.95
8_A	28_G	0.887	0.95
249_A	304_L	0.884	0.95
25_A	149_L	0.884	0.95
84_A	87_L	0.883	0.95
455_Y	524_T	0.883	0.95
10_V	31_V	0.882	0.95
8_A	29_F	0.878	0.95
94_E	97_M	0.877	0.95
216_G	220_R	0.876	0.95
518_R	527_P	0.876	0.95
267_R	288_E	0.875	0.95
88_L	386_L	0.875	0.95
188_K	403_L	0.875	0.95
69_T	85_A	0.873	0.94
301_G	335_P	0.866	0.94
228_P	507_I	0.865	0.94
216_G	503_L	0.863	0.94
444_L	471_L	0.855	0.94
117_R	252_E	0.849	0.94
30_K	150_N	0.848	0.94
70_Y	82_Q	0.847	0.94
165_D	168_K	0.844	0.93
441_L	497_L	0.844	0.93
228_P	503_L	0.843	0.93
73_V	80_V	0.842	0.93
212_G	503_L	0.841	0.93
211_T	496_E	0.841	0.93
73_V	85_A	0.840	0.93
9_V	32_A	0.840	0.93
130_V	137_A	0.836	0.93
444_L	501_L	0.834	0.93
329_V	336_I	0.833	0.93
461_L	508_A	0.830	0.93
228_P	510_S	0.827	0.93
193_A	366_A	0.825	0.93
399_V	403_L	0.824	0.93
516_E	527_P	0.822	0.93
167_K	360_I	0.822	0.93
121_G	346_M	0.822	0.93
83_D	353_I	0.821	0.92
65_P	93_G	0.814	0.92
254_A	304_L	0.813	0.92
268_Y	287_T	0.812	0.92
465_M	469_N	0.812	0.92
37_V	209_I	0.810	0.92
51_I	386_L	0.810	0.92
105_L	141_T	0.805	0.92
81_D	371_C	0.805	0.92
292_G	297_G	0.803	0.92
265_M	273_L	0.802	0.92
472_R	501_L	0.802	0.92
24_I	29_F	0.801	0.92
91_K	393_Q	0.798	0.91
290_K	450_D	0.795	0.91
440_I	497_L	0.793	0.91
176_Q	181_T	0.793	0.91
100_E	108_R	0.792	0.91
448_M	504_A	0.792	0.91
188_K	407_S	0.791	0.91
89_S	92_S	0.788	0.91
518_R	526_Y	0.787	0.91
257_K	301_G	0.786	0.91
224_A	539_I	0.786	0.91
164_T	167_K	0.785	0.91
354_E	394_V	0.783	0.91
9_V	190_V	0.782	0.91
25_A	151_V	0.781	0.90
54_Y	89_S	0.777	0.90
400_V	403_L	0.776	0.90
20_S	24_I	0.776	0.90
259_I	297_G	0.776	0.90
286_I	455_Y	0.772	0.90
99_L	138_L	0.770	0.90
509_K	513_E	0.767	0.90
22_H	145_R	0.767	0.90
290_K	524_T	0.765	0.90
28_G	31_V	0.765	0.90
284_A	287_T	0.764	0.89
439_Q	443_K	0.760	0.89
264_F	268_Y	0.758	0.89
468_I	505_F	0.758	0.89
108_R	114_V	0.758	0.89
287_T	455_Y	0.758	0.89
5_E	30_K	0.756	0.89
506_V	540_A	0.755	0.89
189_A	399_V	0.755	0.89
269_A	277_P	0.754	0.89
320_V	331_A	0.752	0.89
201_Y	507_I	0.752	0.89
227_D	537_H	0.752	0.89
323_A	336_I	0.751	0.89
264_F	267_R	0.750	0.89
25_A	31_V	0.750	0.89
510_S	540_A	0.750	0.89
247_E	250_R	0.749	0.89
19_M	98_L	0.748	0.88
199_M	445_R	0.748	0.88
25_A	28_G	0.747	0.88
205_T	341_A	0.745	0.88
225_L	506_V	0.745	0.88
217_I	220_R	0.744	0.88
264_F	274_D	0.740	0.88
240_P	327_A	0.738	0.88
119_F	127_T	0.737	0.88
117_R	129_F	0.735	0.88
9_V	185_F	0.735	0.88
43_H	46_A	0.735	0.88
52_A	89_S	0.734	0.88
397_R	401_Q	0.732	0.87
52_A	68_M	0.730	0.87
459_G	463_N	0.729	0.87
324_K	332_F	0.728	0.87
140_H	144_E	0.728	0.87
7_D	29_F	0.726	0.87
145_R	149_L	0.726	0.87
60_D	124_Y	0.725	0.87
53_A	96_V	0.725	0.87
534_W	537_H	0.725	0.87
276_A	280_I	0.723	0.87
73_V	82_Q	0.722	0.87
37_V	41_R	0.720	0.87
456_R	521_H	0.719	0.86
231_V	507_I	0.719	0.86
98_L	101_R	0.719	0.86
53_A	128_R	0.719	0.86
284_A	288_E	0.717	0.86
43_H	210_N	0.716	0.86
239_Y	299_Y	0.715	0.86
249_A	312_I	0.714	0.86
64_N	67_Y	0.713	0.86
203_H	449_W	0.709	0.86
442_E	445_R	0.708	0.86
435_V	439_Q	0.708	0.86
259_I	293_R	0.705	0.85
67_Y	70_Y	0.705	0.85
340_P	343_H	0.704	0.85
139_L	143_F	0.703	0.85
164_T	170_A	0.703	0.85
10_V	28_G	0.701	0.85
517_S	522_Y	0.701	0.85
200_L	503_L	0.700	0.85
127_T	381_G	0.700	0.85
172_I	187_T	0.700	0.85
245_I	336_I	0.700	0.85
276_A	281_V	0.700	0.85
94_E	393_Q	0.700	0.85
278_R	282_S	0.699	0.85
366_A	392_G	0.699	0.85
230_F	514_R	0.698	0.85
462_L	509_K	0.698	0.85
402_F	406_N	0.697	0.85
170_A	186_K	0.697	0.85
473_G	476_S	0.697	0.85
29_F	400_V	0.695	0.85
236_T	250_R	0.695	0.85
264_F	288_E	0.695	0.85
119_F	382_S	0.695	0.85
197_M	215_F	0.694	0.84
423_D	426_Y	0.694	0.84
234_H	247_E	0.693	0.84
262_E	288_E	0.693	0.84
364_F	399_V	0.692	0.84
250_R	253_G	0.690	0.84
231_V	345_Y	0.688	0.84
115_A	129_F	0.687	0.84
265_M	269_A	0.686	0.84
105_L	140_H	0.685	0.84
431_S	434_G	0.685	0.84
289_I	299_Y	0.685	0.84
463_N	466_S	0.684	0.84
168_K	402_F	0.684	0.84
259_I	292_G	0.684	0.84
443_K	446_D	0.683	0.84
214_G	369_A	0.682	0.83
259_I	299_Y	0.681	0.83
304_L	312_I	0.681	0.83
286_I	289_I	0.681	0.83
198_G	204_T	0.679	0.83
425_A	483_K	0.679	0.83
100_E	128_R	0.679	0.83
174_A	183_F	0.678	0.83
199_M	500_M	0.676	0.83
311_Y	314_E	0.676	0.83
161_D	221_A	0.676	0.83
15_L	142_L	0.675	0.83
157_W	185_F	0.675	0.83
435_V	443_K	0.675	0.83
245_I	319_A	0.674	0.83
216_G	499_N	0.673	0.83
188_K	409_N	0.673	0.83
279_D	283_R	0.673	0.83
51_I	389_L	0.673	0.83
368_E	379_R	0.670	0.82
105_L	108_R	0.670	0.82
451_Y	508_A	0.669	0.82
160_L	182_P	0.668	0.82
147_S	155_N	0.668	0.82
32_A	152_D	0.666	0.82
471_L	501_L	0.665	0.82
200_L	504_A	0.664	0.82
394_V	398_A	0.663	0.82
401_Q	405_S	0.663	0.82
312_I	331_A	0.662	0.82
95_I	389_L	0.661	0.82
234_H	250_R	0.658	0.81
437_F	494_A	0.658	0.81
79_L	230_F	0.657	0.81
39_P	153_F	0.656	0.81
265_M	268_Y	0.656	0.81
160_L	175_M	0.655	0.81
455_Y	522_Y	0.655	0.81
191_V	403_L	0.655	0.81
189_A	362_G	0.654	0.81
24_I	28_G	0.654	0.81
43_H	207_S	0.654	0.81
15_L	389_L	0.653	0.81
38_F	155_N	0.652	0.81
198_G	206_N	0.650	0.80
502_D	505_F	0.650	0.80
260_K	293_R	0.649	0.80
84_A	372_V	0.649	0.80
52_A	127_T	0.647	0.80
34_I	185_F	0.647	0.80
194_T	369_A	0.644	0.80
10_V	20_S	0.644	0.80
341_A	344_Y	0.642	0.80
163_V	186_K	0.640	0.79
6_Y	185_F	0.640	0.79
169_V	360_I	0.640	0.79
340_P	344_Y	0.638	0.79
289_I	339_R	0.638	0.79
34_I	154_Y	0.638	0.79
396_G	403_L	0.637	0.79
440_I	443_K	0.635	0.79
517_S	527_P	0.635	0.79
62_N	124_Y	0.633	0.79
450_D	460_G	0.633	0.79
46_A	207_S	0.632	0.79
39_P	155_N	0.631	0.78
244_L	247_E	0.629	0.78
197_M	200_L	0.628	0.78
73_V	78_Y	0.627	0.78
50_G	234_H	0.626	0.78
219_L	502_D	0.624	0.78
496_E	500_M	0.624	0.78
330_D	334_E	0.624	0.78
79_L	229_E	0.623	0.78
459_G	462_L	0.623	0.78
226_K	372_V	0.623	0.78
188_K	408_S	0.623	0.78
300_V	338_V	0.623	0.78
51_I	106_F	0.622	0.77
425_A	428_L	0.622	0.77
258_N	263_R	0.620	0.77
219_L	225_L	0.620	0.77
198_G	345_Y	0.620	0.77
470_K	473_G	0.619	0.77
422_V	426_Y	0.619	0.77
60_D	67_Y	0.619	0.77
470_K	474_M	0.618	0.77
27_A	397_R	0.617	0.77
54_Y	69_T	0.617	0.77
26_S	98_L	0.616	0.77
269_A	276_A	0.616	0.77
50_G	54_Y	0.615	0.77
399_V	402_F	0.614	0.77
343_H	380_L	0.614	0.77
468_I	501_L	0.613	0.76
65_P	86_E	0.612	0.76
473_G	477_N	0.612	0.76
22_H	151_V	0.611	0.76
280_I	283_R	0.610	0.76
25_A	400_V	0.608	0.76
160_L	173_V	0.605	0.76
20_S	392_G	0.604	0.75
216_G	502_D	0.604	0.75
286_I	339_R	0.604	0.75
307_L	312_I	0.603	0.75
7_D	32_A	0.603	0.75
438_G	493_N	0.603	0.75
362_G	402_F	0.602	0.75
333_T	410_P	0.601	0.75
464_A	467_E	0.600	0.75
356_R	364_F	0.599	0.75
513_E	538_T	0.599	0.75
13_G	33_V	0.598	0.75
515_K	533_N	0.597	0.75
25_A	148_G	0.597	0.75
351_V	355_G	0.597	0.75
211_T	499_N	0.595	0.74
469_N	473_G	0.594	0.74
243_V	322_A	0.594	0.74
50_G	250_R	0.594	0.74
143_F	146_T	0.594	0.74
269_A	280_I	0.593	0.74
440_I	478_M	0.592	0.74
162_L	192_L	0.592	0.74
116_V	128_R	0.592	0.74
203_H	339_R	0.592	0.74
243_V	319_A	0.592	0.74
97_M	100_E	0.591	0.74
33_V	39_P	0.590	0.74
236_T	247_E	0.589	0.74
42_S	139_L	0.587	0.73
247_E	251_G	0.587	0.73
54_Y	68_M	0.587	0.73
156_E	178_K	0.587	0.73
29_F	403_L	0.587	0.73
434_G	479_Y	0.586	0.73
137_A	141_T	0.586	0.73
104_A	389_L	0.585	0.73
89_S	391_F	0.583	0.73
10_V	191_V	0.582	0.73
169_V	362_G	0.582	0.73
109_Q	115_A	0.582	0.73
162_L	228_P	0.582	0.73
45_A	140_H	0.579	0.72
10_V	399_V	0.578	0.72
447_T	468_I	0.577	0.72
292_G	299_Y	0.577	0.72
308_G	332_F	0.576	0.72
382_S	387_D	0.576	0.72
214_G	221_A	0.576	0.72
356_R	361_V	0.574	0.72
440_I	501_L	0.574	0.72
353_I	391_F	0.573	0.72
144_E	147_S	0.573	0.72
450_D	463_N	0.573	0.72
391_F	394_V	0.572	0.71
265_M	276_A	0.570	0.71
117_R	315_R	0.570	0.71
10_V	21_A	0.569	0.71
19_M	102_W	0.568	0.71
469_N	472_R	0.567	0.71
229_E	510_S	0.566	0.71
256_L	265_M	0.566	0.71
119_F	381_G	0.566	0.71
475_I	478_M	0.566	0.71
534_W	538_T	0.564	0.70
366_A	388_T	0.563	0.70
245_I	322_A	0.562	0.70
141_T	145_R	0.562	0.70
448_M	451_Y	0.562	0.70
233_F	453_G	0.561	0.70
23_E	392_G	0.560	0.70
163_V	170_A	0.559	0.70
441_L	496_E	0.559	0.70
50_G	53_A	0.558	0.70
172_I	190_V	0.557	0.69
8_A	27_A	0.555	0.69
120_G	271_K	0.555	0.69
258_N	267_R	0.553	0.69
249_A	319_A	0.553	0.69
322_A	327_A	0.553	0.69
515_K	523_R	0.552	0.69
516_E	526_Y	0.552	0.69
238_L	357_N	0.551	0.69
289_I	292_G	0.551	0.69
299_Y	337_P	0.550	0.68
177_M	492_F	0.548	0.68
91_K	390_V	0.547	0.68
119_F	122_Q	0.546	0.68
198_G	231_V	0.545	0.68
19_M	392_G	0.545	0.68
443_K	470_K	0.545	0.68
511_A	517_S	0.545	0.68
460_G	464_A	0.544	0.68
245_I	338_V	0.543	0.67
258_N	264_F	0.543	0.67
186_K	409_N	0.542	0.67
38_F	156_E	0.542	0.67
513_E	536_K	0.541	0.67
238_L	241_S	0.541	0.67
255_I	273_L	0.540	0.67
466_S	469_N	0.539	0.67
426_Y	430_K	0.537	0.67
530_D	534_W	0.537	0.67
267_R	274_D	0.536	0.66
344_Y	347_G	0.535	0.66
312_I	324_K	0.535	0.66
132_D	251_G	0.535	0.66
169_V	363_L	0.534	0.66
167_K	170_A	0.534	0.66
441_L	493_N	0.533	0.66
190_V	362_G	0.532	0.66
35_S	155_N	0.532	0.66
430_K	470_K	0.532	0.66
20_S	31_V	0.532	0.66
132_D	250_R	0.531	0.66
133_K	137_A	0.530	0.66
69_T	90_N	0.529	0.65
271_K	280_I	0.528	0.65
55_I	116_V	0.528	0.65
72_T	85_A	0.528	0.65
170_A	361_V	0.527	0.65
86_E	89_S	0.526	0.65
343_H	379_R	0.526	0.65
279_D	282_S	0.526	0.65
312_I	335_P	0.525	0.65
138_L	389_L	0.524	0.65
158_F	492_F	0.524	0.65
158_F	499_N	0.524	0.65
310_E	313_K	0.523	0.65
213_D	496_E	0.523	0.65
533_N	536_K	0.523	0.65
432_E	479_Y	0.522	0.64
170_A	190_V	0.521	0.64
232_Q	379_R	0.521	0.64
408_S	411_T	0.521	0.64
392_G	399_V	0.520	0.64
508_A	512_L	0.520	0.64
324_K	330_D	0.518	0.64
277_P	280_I	0.517	0.64
27_A	401_Q	0.517	0.64
75_G	381_G	0.516	0.64
259_I	301_G	0.516	0.64
285_I	338_V	0.515	0.63
164_T	361_V	0.515	0.63
304_L	308_G	0.514	0.63
34_I	157_W	0.514	0.63
175_M	495_L	0.514	0.63
236_T	278_R	0.514	0.63
509_K	512_L	0.513	0.63
24_I	400_V	0.512	0.63
63_D	71_D	0.512	0.63
461_L	511_A	0.511	0.63
478_M	494_A	0.511	0.63
264_F	344_Y	0.510	0.63
370_A	391_F	0.509	0.63
278_R	378_N	0.508	0.62
444_L	500_M	0.508	0.62
48_E	250_R	0.507	0.62
141_T	144_E	0.506	0.62
423_D	427_K	0.505	0.62
227_D	371_C	0.505	0.62
200_L	500_M	0.504	0.62
35_S	153_F	0.504	0.62
107_N	131_G	0.503	0.62
264_F	284_A	0.502	0.61
190_V	217_I	0.502	0.61
339_R	449_W	0.502	0.61
70_Y	73_V	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bs2A	2	0.9965	100	0.233	Contact Map
2h88A	2	0.9929	100	0.244	Contact Map
1kf6A	1	0.9841	100	0.247	Contact Map
2wdqA	1	0.9894	100	0.259	Contact Map
3gyxA	2	0.9435	100	0.351	Contact Map
1chuA	2	0.8198	100	0.353	Contact Map
2e5vA	1	0.8304	100	0.385	Contact Map
1jnrA	2	0.9382	100	0.386	Contact Map
4c3xA	4	0.6696	100	0.599	Contact Map
4at0A	2	0.6661	100	0.652	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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