GREMLIN Database
Q97W58 - Uncharacterized protein
UniProt: Q97W58 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 111 (94)
Sequences: 160 (124)
Seq/√Len: 12.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
29_I72_A3.2910.98
80_N104_K3.1950.98
92_V106_A2.8810.95
31_I65_A2.6800.93
77_I82_A2.6590.93
55_Y105_F2.6040.92
85_E89_R2.1390.82
16_V29_I2.1070.81
60_V65_A2.0180.78
20_I39_K1.8250.70
77_I102_G1.8230.70
16_V65_A1.6560.62
17_L30_N1.5620.58
30_N105_F1.5290.56
64_Y67_S1.5180.55
24_Q61_E1.4630.53
36_L96_S1.4550.52
40_V52_E1.4480.52
31_I83_V1.4410.51
40_V49_D1.4270.51
55_Y90_G1.4180.50
35_E81_Y1.4160.50
19_N30_N1.3650.47
77_I86_A1.3120.45
93_H96_S1.3110.45
36_L45_E1.2900.44
18_L44_G1.2670.42
32_C72_A1.2600.42
64_Y69_I1.2480.41
21_I30_N1.2430.41
34_E59_S1.2330.41
72_A75_M1.2140.40
28_L101_A1.1900.39
59_S65_A1.1870.38
54_F107_Q1.1760.38
20_I88_R1.1710.38
23_A26_M1.1630.37
33_Q76_S1.1000.34
41_F48_L1.0970.34
36_L104_K1.0830.33
20_I23_A1.0740.33
16_V85_E1.0530.32
65_A71_E1.0500.32
41_F109_Y1.0240.31
63_D67_S1.0160.30
43_E46_I1.0090.30
29_I32_C1.0050.30
21_I28_L0.9920.29
60_V64_Y0.9870.29
63_D73_T0.9700.28
60_V84_E0.9610.28
35_E63_D0.9610.28
40_V47_I0.9600.28
24_Q70_D0.9580.28
54_F106_A0.9360.27
33_Q105_F0.9300.27
49_D95_D0.9240.27
19_N41_F0.9200.26
18_L65_A0.9140.26
40_V69_I0.8960.25
86_A106_A0.8860.25
60_V103_I0.8840.25
77_I95_D0.8830.25
54_F86_A0.8770.25
16_V72_A0.8770.25
62_L85_E0.8760.25
34_E81_Y0.8740.25
21_I109_Y0.8680.24
52_E56_G0.8640.24
37_L90_G0.8620.24
16_V62_L0.8610.24
27_T58_E0.8580.24
46_I51_S0.8520.24
23_A74_V0.8500.24
32_C37_L0.8470.24
36_L74_V0.8370.23
55_Y107_Q0.8350.23
48_L78_V0.8220.23
44_G57_G0.8180.22
19_N36_L0.8140.22
26_M74_V0.8020.22
75_M93_H0.8010.22
65_A82_A0.8000.22
80_N84_E0.7970.22
23_A28_L0.7780.21
29_I65_A0.7740.21
54_F105_F0.7690.21
50_I96_S0.7690.21
30_N54_F0.7580.20
41_F89_R0.7580.20
60_V68_L0.7410.20
30_N68_L0.7360.20
46_I87_I0.7320.20
27_T71_E0.7210.19
37_L78_V0.7180.19
61_E65_A0.7120.19
38_G90_G0.7110.19
19_N80_N0.7000.19
63_D66_L0.6830.18
54_F72_A0.6740.18
86_A107_Q0.6690.18
36_L41_F0.6630.17
86_A92_V0.6590.17
34_E95_D0.6530.17
65_A83_V0.6520.17
36_L95_D0.6490.17
42_R51_S0.6390.17
18_L60_V0.6380.17
77_I84_E0.6320.16
18_L30_N0.6310.16
81_Y97_V0.6230.16
34_E40_V0.6140.16
77_I103_I0.6140.16
21_I74_V0.6120.16
41_F46_I0.6080.16
58_E95_D0.5970.16
48_L66_L0.5970.16
75_M108_V0.5960.15
47_I72_A0.5900.15
70_D91_L0.5850.15
58_E97_V0.5840.15
43_E99_N0.5830.15
39_K101_A0.5820.15
66_L89_R0.5720.15
36_L97_V0.5710.15
64_Y84_E0.5630.15
50_I78_V0.5600.15
50_I98_I0.5570.14
45_E49_D0.5520.14
53_K94_K0.5380.14
95_D109_Y0.5370.14
34_E83_V0.5370.14
51_S69_I0.5340.14
31_I82_A0.5330.14
60_V100_V0.5300.14
63_D69_I0.5300.14
50_I108_V0.5190.14
53_K60_V0.5090.13
30_N76_S0.5070.13
98_I105_F0.5020.13
94_K103_I0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qyaA 2 0.8829 100 0.208 Contact Map
4wweA 1 0.4054 22.4 0.932 Contact Map
4wwtA 1 0.4054 21.4 0.932 Contact Map
3r07C 1 0.7477 15.8 0.936 Contact Map
1rm6B 1 0.5766 15.4 0.936 Contact Map
2ov7A 1 0.5856 11.3 0.94 Contact Map
1t3qC 1 0.5676 10.2 0.941 Contact Map
1n62C 1 0.5676 8.4 0.944 Contact Map
3r8eA 2 0.7658 8 0.944 Contact Map
4k0mC 1 0.4144 7.9 0.944 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0052 seconds.