Q97W24 - SULSO - GREMLIN Contacts

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Q97W24 - Phytoene dehydrogenase related protein

UniProt:	Q97W24	Sequences: MIDVAIIGGGHNGLVTAAYLAKAGLKVAVFERREIVGGASVTEELWPSIKVSTGAYVLSLLRPKIIEELKLREFGLKVYLKDPGLFLPFENGKKLYIWSSLEKTKKEIEKFSKNDAKNYKKWVKFWDLFAEMADFFMLNPPPHIDEASNLINIFRGNVNEELALSFLRTFMQDAKSLLDEYFETDEVKSALAEDSVVGTFASPSTPGTAYVLAHHVIGEVNGVKGAWGYVEGGMGEVTQALKRSAEHLGVEIYTNAEVDEVLVKNGRVEGIKLKNGKTINAKIIVSNADPKTTFFKLLRNAELEEDFLRRVRALKNVGVSFKIVGYLEELPDFGNGKSLSPEHIASELIMPNMEYIEKAYDDARALGYSREPWLSINIQSSVDPTVAPPGKFSFSIFGQYLVYDSKRNDEMKEKIAEITFEKIKEFAPNFKPIKYEVLTPLDIERRFGINGGNIFHLDMTPDQLYFFRPLIGYSDYTTPIRGLYLCGSGTHPGGGVTGAPGYNAHVKILEDLRKGIYK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	518 (438)
Sequences:	14428 (11246)
Seq/√Len:	537.4

ECOLI - GLF
BACSU - PPOX YOBN
HALSA - Q9HP88 Q9HPD8 Q9HSE1 Q9HRU3 Q9HP54 Q9HRN2
SULSO - Q97W24 Q97UT6 Q97YW3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
3_D	26_K	4.376	1.00
5_A	281_A	4.252	1.00
77_K	231_E	4.024	1.00
245_A	250_V	3.898	1.00
28_A	253_Y	3.870	1.00
3_D	282_K	3.747	1.00
32_R	257_E	3.707	1.00
36_V	254_T	3.605	1.00
260_E	272_K	3.573	1.00
16_T	285_V	3.383	1.00
30_F	279_I	3.243	1.00
286_S	293_T	3.079	1.00
36_V	242_K	3.070	1.00
262_L	272_K	2.985	1.00
5_A	30_F	2.984	1.00
272_K	278_T	2.937	1.00
9_G	36_V	2.926	1.00
34_E	255_N	2.895	1.00
5_A	279_I	2.834	1.00
501_G	505_H	2.776	1.00
235_G	239_Q	2.710	1.00
68_E	71_L	2.705	1.00
411_M	414_K	2.617	1.00
26_K	251_E	2.596	1.00
5_A	271_I	2.593	1.00
259_D	274_K	2.568	1.00
257_E	274_K	2.529	1.00
256_A	273_L	2.529	1.00
236_E	239_Q	2.449	1.00
273_L	279_I	2.435	1.00
7_I	286_S	2.425	1.00
242_K	246_E	2.385	1.00
79_Y	231_E	2.347	1.00
172_Q	180_E	2.319	1.00
424_K	431_K	2.317	1.00
30_F	253_Y	2.300	1.00
242_K	252_I	2.256	1.00
253_Y	256_A	2.222	1.00
4_V	25_L	2.197	1.00
68_E	72_R	2.197	1.00
19_Y	502_Y	2.171	1.00
44_E	50_K	2.166	1.00
287_N	486_C	2.157	1.00
283_I	484_Y	2.112	1.00
3_D	28_A	2.025	1.00
30_F	281_A	2.000	1.00
12_N	287_N	1.999	1.00
175_K	179_D	1.975	1.00
23_A	509_L	1.971	1.00
35_I	41_V	1.967	1.00
285_V	508_I	1.965	1.00
173_D	176_S	1.945	1.00
424_K	429_N	1.938	1.00
11_H	496_V	1.926	1.00
269_E	280_N	1.921	1.00
7_I	288_A	1.915	1.00
105_K	120_K	1.902	1.00
240_A	243_R	1.883	1.00
264_K	269_E	1.882	1.00
18_A	244_S	1.877	1.00
42_T	50_K	1.873	1.00
179_D	188_K	1.861	1.00
417_E	421_E	1.843	1.00
253_Y	279_I	1.799	1.00
64_K	502_Y	1.771	1.00
4_V	283_I	1.759	1.00
19_Y	506_V	1.758	1.00
19_Y	22_K	1.741	1.00
17_A	29_V	1.735	1.00
25_L	509_L	1.734	1.00
261_V	268_V	1.730	1.00
259_D	272_K	1.726	1.00
268_V	284_I	1.710	1.00
262_L	278_T	1.704	1.00
256_A	275_N	1.699	1.00
262_L	269_E	1.678	1.00
28_A	251_E	1.673	1.00
413_E	417_E	1.665	1.00
288_A	293_T	1.655	1.00
486_C	504_A	1.644	1.00
269_E	278_T	1.598	1.00
253_Y	277_K	1.542	1.00
246_E	249_G	1.530	1.00
36_V	238_T	1.527	1.00
246_E	251_E	1.521	1.00
258_V	271_I	1.510	1.00
175_K	204_S	1.490	1.00
3_D	25_L	1.488	1.00
18_A	22_K	1.480	1.00
49_I	326_Y	1.476	1.00
100_S	103_K	1.476	1.00
40_S	238_T	1.473	1.00
328_E	391_K	1.469	1.00
245_A	252_I	1.467	1.00
30_F	258_V	1.462	1.00
28_A	279_I	1.461	1.00
239_Q	243_R	1.443	1.00
283_I	508_I	1.436	1.00
429_N	432_P	1.430	1.00
246_E	250_V	1.425	1.00
5_A	28_A	1.422	1.00
268_V	482_G	1.407	1.00
9_G	29_V	1.406	1.00
127_D	131_E	1.399	1.00
260_E	299_R	1.384	1.00
29_V	252_I	1.382	1.00
6_I	17_A	1.375	1.00
503_N	507_K	1.370	1.00
172_Q	176_S	1.369	1.00
28_A	281_A	1.367	1.00
4_V	20_L	1.365	1.00
428_P	431_K	1.364	1.00
328_E	434_K	1.364	1.00
243_R	246_E	1.354	1.00
36_V	252_I	1.345	1.00
504_A	507_K	1.345	1.00
13_G	287_N	1.343	1.00
239_Q	242_K	1.343	1.00
121_K	125_F	1.338	1.00
416_A	420_F	1.331	1.00
234_M	496_V	1.324	1.00
64_K	67_E	1.323	1.00
417_E	431_K	1.300	1.00
288_A	297_L	1.296	1.00
263_V	268_V	1.288	1.00
327_L	420_F	1.276	1.00
18_A	241_L	1.273	1.00
65_I	68_E	1.271	1.00
21_A	250_V	1.269	1.00
39_A	488_S	1.264	1.00
410_E	414_K	1.260	1.00
421_E	431_K	1.260	1.00
281_A	284_I	1.248	1.00
416_A	435_Y	1.248	1.00
289_D	292_T	1.248	1.00
12_N	486_C	1.246	1.00
67_E	72_R	1.242	1.00
484_Y	504_A	1.233	1.00
290_P	489_G	1.226	1.00
30_F	273_L	1.212	1.00
407_R	410_E	1.207	1.00
30_F	256_A	1.204	1.00
21_A	27_V	1.202	1.00
484_Y	508_I	1.202	1.00
12_N	500_P	1.192	1.00
490_T	503_N	1.191	1.00
44_E	235_G	1.189	1.00
105_K	109_E	1.180	1.00
441_L	444_E	1.175	1.00
128_L	131_E	1.163	1.00
418_I	421_E	1.159	1.00
422_K	425_E	1.159	1.00
18_A	245_A	1.159	1.00
102_E	105_K	1.157	1.00
420_F	424_K	1.149	1.00
118_N	121_K	1.145	1.00
261_V	284_I	1.144	1.00
264_K	280_N	1.143	1.00
273_L	277_K	1.137	1.00
131_E	134_D	1.136	1.00
43_E	53_T	1.133	1.00
93_K	186_E	1.131	1.00
20_L	505_H	1.129	1.00
502_Y	506_V	1.128	1.00
125_F	128_L	1.127	1.00
103_K	106_K	1.126	1.00
103_K	107_E	1.122	1.00
292_T	296_K	1.118	1.00
202_S	205_T	1.117	1.00
65_I	70_K	1.117	1.00
325_G	420_F	1.116	1.00
256_A	279_I	1.111	1.00
371_E	425_E	1.107	1.00
230_V	237_V	1.106	1.00
44_E	48_S	1.106	1.00
127_D	130_A	1.104	1.00
75_G	78_V	1.104	1.00
6_I	27_V	1.103	1.00
124_K	127_D	1.099	1.00
267_R	280_N	1.096	1.00
308_L	312_R	1.087	1.00
98_W	103_K	1.086	1.00
242_K	254_T	1.085	1.00
438_L	442_D	1.082	1.00
117_K	121_K	1.082	1.00
490_T	500_P	1.079	1.00
104_T	107_E	1.070	1.00
345_A	349_I	1.066	1.00
69_L	72_R	1.065	1.00
273_L	276_G	1.060	1.00
428_P	432_P	1.058	1.00
283_I	482_G	1.057	1.00
480_I	483_L	1.056	1.00
232_G	236_E	1.052	1.00
286_S	483_L	1.050	1.00
64_K	68_E	1.042	1.00
19_Y	501_G	1.039	1.00
11_H	40_S	1.036	1.00
261_V	286_S	1.033	1.00
19_Y	68_E	1.033	1.00
494_G	499_A	1.032	1.00
414_K	417_E	1.032	1.00
86_F	96_Y	1.030	1.00
309_R	312_R	1.028	1.00
3_D	279_I	1.028	1.00
423_I	427_A	1.025	1.00
263_V	482_G	1.024	1.00
236_E	240_A	1.020	1.00
21_A	245_A	1.013	1.00
264_K	267_R	1.011	1.00
484_Y	507_K	1.010	1.00
400_Y	403_Y	1.006	1.00
347_E	350_M	1.002	1.00
495_G	499_A	0.998	1.00
3_D	280_N	0.996	1.00
9_G	254_T	0.993	1.00
25_L	28_A	0.993	1.00
346_S	350_M	0.992	1.00
345_A	348_L	0.992	1.00
421_E	425_E	0.989	1.00
19_Y	23_A	0.985	1.00
414_K	418_I	0.977	1.00
49_I	391_K	0.972	1.00
260_E	300_N	0.966	1.00
67_E	71_L	0.963	1.00
487_G	500_P	0.962	1.00
106_K	109_E	0.958	1.00
504_A	508_I	0.957	1.00
172_Q	177_L	0.956	1.00
28_A	282_K	0.955	1.00
375_S	378_I	0.955	1.00
475_D	478_T	0.954	1.00
22_K	71_L	0.952	1.00
128_L	132_M	0.951	1.00
49_I	388_P	0.951	1.00
412_K	440_P	0.951	1.00
244_S	247_H	0.946	1.00
423_I	430_F	0.945	1.00
325_G	396_I	0.943	1.00
416_A	419_T	0.937	1.00
24_G	27_V	0.936	1.00
259_D	273_L	0.935	1.00
199_T	203_P	0.931	1.00
416_A	436_E	0.929	1.00
375_S	379_Q	0.928	1.00
398_G	419_T	0.924	1.00
121_K	124_K	0.923	1.00
177_L	181_Y	0.922	1.00
188_K	192_A	0.921	1.00
421_E	424_K	0.918	1.00
261_V	271_I	0.918	1.00
441_L	445_R	0.915	1.00
66_I	69_L	0.911	1.00
98_W	107_E	0.905	1.00
505_H	508_I	0.899	1.00
130_A	133_A	0.896	1.00
238_T	242_K	0.893	1.00
373_W	378_I	0.893	1.00
207_G	210_Y	0.889	1.00
29_V	245_A	0.887	1.00
397_F	400_Y	0.887	1.00
374_L	377_N	0.887	1.00
243_R	247_H	0.886	1.00
33_R	41_V	0.882	1.00
124_K	128_L	0.881	1.00
256_A	277_K	0.878	1.00
17_A	250_V	0.877	1.00
66_I	70_K	0.875	1.00
7_I	258_V	0.872	1.00
42_T	235_G	0.871	1.00
22_K	244_S	0.870	1.00
230_V	236_E	0.870	1.00
40_S	55_A	0.868	1.00
257_E	296_K	0.866	1.00
262_L	300_N	0.865	1.00
309_R	313_A	0.864	1.00
259_D	262_L	0.864	1.00
184_T	187_V	0.863	1.00
476_Y	479_P	0.859	1.00
373_W	376_I	0.858	1.00
440_P	444_E	0.856	1.00
192_A	203_P	0.855	1.00
130_A	134_D	0.855	1.00
285_V	484_Y	0.852	1.00
165_S	168_R	0.852	1.00
304_E	480_I	0.852	1.00
15_V	241_L	0.851	1.00
440_P	443_I	0.848	1.00
456_H	460_T	0.848	1.00
401_L	404_D	0.846	1.00
267_R	481_R	0.844	1.00
506_V	510_E	0.840	1.00
33_R	450_N	0.839	1.00
26_K	282_K	0.839	1.00
199_T	206_P	0.838	1.00
17_A	245_A	0.838	1.00
31_E	254_T	0.835	1.00
263_V	480_I	0.831	1.00
345_A	350_M	0.831	1.00
6_I	13_G	0.829	1.00
120_K	123_V	0.827	1.00
347_E	352_N	0.824	1.00
39_A	54_G	0.824	1.00
438_L	443_I	0.824	1.00
179_D	184_T	0.824	1.00
494_G	498_G	0.822	1.00
434_K	437_V	0.820	1.00
64_K	70_K	0.819	1.00
455_F	461_P	0.819	1.00
223_V	226_A	0.818	1.00
269_E	272_K	0.818	1.00
396_I	423_I	0.817	1.00
395_S	398_G	0.816	1.00
104_T	108_I	0.814	1.00
412_K	416_A	0.814	1.00
185_D	189_S	0.813	1.00
225_G	228_G	0.813	1.00
15_V	19_Y	0.811	1.00
371_E	422_K	0.809	1.00
295_F	312_R	0.809	1.00
258_V	273_L	0.808	1.00
6_I	285_V	0.808	1.00
433_I	436_E	0.804	1.00
3_D	281_A	0.802	1.00
25_L	282_K	0.802	1.00
260_E	298_L	0.800	1.00
11_H	15_V	0.798	1.00
458_D	461_P	0.797	1.00
305_E	309_R	0.796	1.00
55_A	234_M	0.795	1.00
422_K	426_F	0.793	1.00
271_I	284_I	0.792	1.00
15_V	501_G	0.790	1.00
16_T	501_G	0.790	1.00
14_L	29_V	0.789	1.00
178_L	192_A	0.788	1.00
200_F	205_T	0.783	1.00
424_K	432_P	0.783	1.00
21_A	251_E	0.782	1.00
289_D	450_N	0.781	1.00
120_K	124_K	0.780	1.00
372_P	378_I	0.779	1.00
420_F	431_K	0.778	1.00
259_D	275_N	0.772	1.00
413_E	416_A	0.772	1.00
477_T	507_K	0.771	1.00
126_W	133_A	0.768	1.00
132_M	135_F	0.763	1.00
213_A	216_V	0.761	1.00
307_F	479_P	0.761	1.00
439_T	442_D	0.758	1.00
240_A	244_S	0.755	1.00
70_K	75_G	0.754	1.00
378_I	381_S	0.753	1.00
203_P	209_A	0.753	1.00
399_Q	403_Y	0.749	1.00
288_A	292_T	0.747	1.00
117_K	120_K	0.746	1.00
71_L	75_G	0.746	1.00
35_I	235_G	0.746	1.00
11_H	238_T	0.746	1.00
177_L	208_T	0.745	1.00
373_W	379_Q	0.742	1.00
67_E	70_K	0.742	1.00
391_K	434_K	0.742	1.00
284_I	482_G	0.741	1.00
327_L	433_I	0.732	1.00
459_M	462_D	0.729	1.00
12_N	499_A	0.729	1.00
102_E	106_K	0.728	1.00
185_D	188_K	0.728	1.00
75_G	247_H	0.727	1.00
290_P	311_V	0.723	1.00
183_E	187_V	0.721	1.00
199_T	207_G	0.720	1.00
184_T	188_K	0.719	1.00
439_T	444_E	0.718	1.00
11_H	499_A	0.717	1.00
23_A	506_V	0.713	1.00
374_L	379_Q	0.711	1.00
372_P	375_S	0.711	1.00
101_L	105_K	0.710	1.00
193_E	196_V	0.710	1.00
380_S	392_F	0.709	1.00
33_R	444_E	0.709	1.00
417_E	420_F	0.705	1.00
460_T	463_Q	0.705	1.00
326_Y	391_K	0.705	1.00
326_Y	434_K	0.703	1.00
165_S	169_T	0.702	1.00
130_A	136_F	0.702	1.00
16_T	504_A	0.702	1.00
52_S	234_M	0.700	1.00
129_F	133_A	0.696	1.00
71_L	247_H	0.691	1.00
345_A	351_P	0.690	1.00
40_S	496_V	0.689	1.00
127_D	134_D	0.687	1.00
11_H	241_L	0.685	1.00
344_I	347_E	0.684	1.00
120_K	125_F	0.684	1.00
267_R	282_K	0.680	1.00
372_P	376_I	0.680	1.00
418_I	422_K	0.680	1.00
78_V	81_K	0.679	1.00
439_T	443_I	0.678	1.00
307_F	310_R	0.677	1.00
201_A	205_T	0.677	1.00
6_I	29_V	0.673	1.00
374_L	378_I	0.672	1.00
25_L	283_I	0.670	1.00
192_A	196_V	0.669	1.00
40_S	234_M	0.666	1.00
299_R	302_E	0.661	1.00
454_I	457_L	0.660	1.00
442_D	445_R	0.660	1.00
267_R	482_G	0.660	1.00
286_S	485_L	0.660	1.00
412_K	415_I	0.660	1.00
18_A	71_L	0.660	1.00
83_P	86_F	0.657	1.00
56_Y	395_S	0.657	1.00
81_K	84_G	0.657	1.00
290_P	314_L	0.655	1.00
372_P	422_K	0.654	1.00
65_I	71_L	0.654	1.00
242_K	250_V	0.654	1.00
30_F	271_I	0.653	1.00
455_F	459_M	0.653	1.00
325_G	416_A	0.652	1.00
182_F	191_L	0.652	1.00
415_I	438_L	0.648	1.00
505_H	509_L	0.647	1.00
326_Y	435_Y	0.646	1.00
199_T	210_Y	0.644	1.00
212_L	215_H	0.644	1.00
182_F	186_E	0.643	1.00
283_I	286_S	0.642	1.00
257_E	449_I	0.642	1.00
193_E	197_V	0.642	1.00
130_A	135_F	0.642	1.00
289_D	489_G	0.641	1.00
372_P	379_Q	0.640	1.00
344_I	348_L	0.638	1.00
486_C	501_G	0.637	1.00
14_L	238_T	0.634	1.00
259_D	276_G	0.634	1.00
102_E	120_K	0.633	1.00
346_S	349_I	0.632	1.00
176_S	180_E	0.631	1.00
62_R	497_T	0.629	1.00
200_F	203_P	0.628	1.00
299_R	303_L	0.628	1.00
75_G	243_R	0.627	1.00
133_A	136_F	0.627	1.00
457_L	461_P	0.626	1.00
329_E	332_D	0.625	1.00
373_W	422_K	0.623	1.00
125_F	132_M	0.621	1.00
29_V	36_V	0.620	1.00
466_F	469_P	0.620	1.00
203_P	206_P	0.619	1.00
136_F	140_P	0.618	1.00
100_S	104_T	0.617	1.00
4_V	508_I	0.617	1.00
134_D	139_N	0.617	1.00
66_I	71_L	0.617	1.00
179_D	204_S	0.616	1.00
327_L	394_F	0.616	1.00
34_E	254_T	0.615	1.00
80_L	228_G	0.614	1.00
91_N	186_E	0.613	1.00
170_F	173_D	0.613	1.00
344_I	349_I	0.613	1.00
65_I	69_L	0.613	1.00
285_V	504_A	0.613	1.00
321_F	437_V	0.612	1.00
350_M	353_M	0.609	1.00
65_I	72_R	0.609	1.00
132_M	136_F	0.608	1.00
189_S	193_E	0.607	1.00
42_T	52_S	0.605	1.00
330_L	392_F	0.605	1.00
398_G	403_Y	0.601	1.00
128_L	133_A	0.601	1.00
14_L	245_A	0.601	1.00
51_V	324_V	0.600	1.00
329_E	392_F	0.600	1.00
94_K	97_I	0.599	1.00
175_K	192_A	0.599	1.00
214_H	217_I	0.597	1.00
122_W	126_W	0.597	1.00
129_F	132_M	0.597	1.00
56_Y	377_N	0.596	1.00
42_T	233_G	0.595	1.00
232_G	383_D	0.594	1.00
224_K	227_W	0.593	1.00
188_K	193_E	0.593	1.00
304_E	308_L	0.589	1.00
478_T	485_L	0.588	0.99
5_A	284_I	0.588	0.99
196_V	202_S	0.587	0.99
239_Q	246_E	0.587	0.99
407_R	411_M	0.587	0.99
436_E	440_P	0.587	0.99
398_G	401_L	0.586	0.99
435_Y	441_L	0.585	0.99
455_F	488_S	0.585	0.99
256_A	276_G	0.583	0.99
135_F	139_N	0.581	0.99
452_G	455_F	0.581	0.99
18_A	250_V	0.581	0.99
236_E	243_R	0.580	0.99
298_L	302_E	0.580	0.99
82_D	86_F	0.580	0.99
122_W	125_F	0.578	0.99
349_I	352_N	0.577	0.99
227_W	230_V	0.576	0.99
82_D	85_L	0.576	0.99
67_E	502_Y	0.576	0.99
183_E	186_E	0.576	0.99
327_L	332_D	0.576	0.99
101_L	104_T	0.575	0.99
96_Y	99_S	0.574	0.99
45_L	326_Y	0.574	0.99
39_A	449_I	0.573	0.99
223_V	227_W	0.573	0.99
282_K	482_G	0.573	0.99
261_V	297_L	0.572	0.99
41_V	53_T	0.571	0.99
201_A	204_S	0.571	0.99
134_D	138_L	0.569	0.99
178_L	188_K	0.568	0.99
383_D	386_V	0.568	0.99
291_K	316_N	0.568	0.99
323_I	419_T	0.568	0.99
263_V	266_G	0.568	0.99
44_E	47_P	0.567	0.99
166_F	170_F	0.567	0.99
406_K	409_D	0.565	0.99
320_S	454_I	0.565	0.99
45_L	436_E	0.564	0.99
15_V	65_I	0.563	0.99
387_A	390_G	0.563	0.99
199_T	202_S	0.563	0.99
78_V	228_G	0.562	0.99
35_I	239_Q	0.562	0.99
128_L	136_F	0.561	0.99
55_A	496_V	0.560	0.99
417_E	435_Y	0.560	0.99
323_I	416_A	0.559	0.99
396_I	400_Y	0.559	0.99
18_A	69_L	0.557	0.99
76_L	79_Y	0.557	0.99
9_G	242_K	0.557	0.99
438_L	441_L	0.557	0.99
323_I	437_V	0.555	0.99
460_T	464_L	0.555	0.99
251_E	254_T	0.552	0.99
400_Y	404_D	0.552	0.99
9_G	14_L	0.552	0.99
491_H	503_N	0.551	0.99
395_S	399_Q	0.551	0.99
325_G	430_F	0.550	0.99
201_A	206_P	0.549	0.99
200_F	207_G	0.549	0.99
293_T	297_L	0.548	0.99
69_L	230_V	0.548	0.99
392_F	395_S	0.547	0.99
388_P	391_K	0.547	0.99
503_N	506_V	0.546	0.99
408_N	412_K	0.545	0.99
410_E	415_I	0.545	0.99
263_V	483_L	0.544	0.99
328_E	433_I	0.544	0.99
178_L	182_F	0.544	0.99
52_S	56_Y	0.543	0.99
486_C	500_P	0.543	0.99
397_F	401_L	0.542	0.99
330_L	334_G	0.541	0.99
135_F	138_L	0.541	0.99
41_V	439_T	0.540	0.99
285_V	486_C	0.540	0.99
52_S	57_V	0.540	0.99
263_V	267_R	0.539	0.99
387_A	391_K	0.539	0.99
22_K	68_E	0.538	0.99
329_E	335_N	0.538	0.99
123_V	127_D	0.538	0.99
21_A	246_E	0.538	0.99
415_I	419_T	0.538	0.99
323_I	396_I	0.537	0.99
436_E	441_L	0.537	0.99
186_E	190_A	0.535	0.99
507_K	510_E	0.535	0.99
456_H	489_G	0.534	0.99
104_T	109_E	0.534	0.99
98_W	101_L	0.533	0.99
233_G	236_E	0.532	0.99
131_E	135_F	0.532	0.99
20_L	508_I	0.532	0.99
77_K	232_G	0.531	0.99
415_I	418_I	0.531	0.99
205_T	209_A	0.530	0.99
321_F	415_I	0.530	0.99
10_G	13_G	0.529	0.99
293_T	485_L	0.529	0.99
136_F	139_N	0.529	0.99
178_L	191_L	0.528	0.99
399_Q	402_V	0.528	0.99
55_A	59_S	0.526	0.99
121_K	128_L	0.524	0.99
406_K	410_E	0.524	0.99
393_S	397_F	0.522	0.99
126_W	130_A	0.522	0.99
434_K	438_L	0.522	0.99
119_Y	122_W	0.521	0.99
35_I	254_T	0.520	0.99
343_H	346_S	0.517	0.99
327_L	333_F	0.517	0.99
452_G	460_T	0.516	0.99
164_L	167_L	0.516	0.99
80_L	99_S	0.515	0.99
347_E	351_P	0.514	0.99
190_A	193_E	0.513	0.99
27_V	250_V	0.513	0.99
118_N	182_F	0.512	0.99
182_F	187_V	0.511	0.99
292_T	295_F	0.511	0.99
163_A	166_F	0.511	0.99
453_N	458_D	0.511	0.99
9_G	31_E	0.508	0.99
200_F	206_P	0.507	0.99
304_E	307_F	0.507	0.99
307_F	311_V	0.507	0.99
77_K	80_L	0.507	0.99
416_A	437_V	0.507	0.99
120_K	127_D	0.506	0.98
452_G	456_H	0.506	0.98
213_A	217_I	0.506	0.98
134_D	137_M	0.506	0.98
97_I	100_S	0.506	0.98
348_L	351_P	0.506	0.98
128_L	134_D	0.506	0.98
51_V	393_S	0.505	0.98
328_E	432_P	0.504	0.98
6_I	10_G	0.503	0.98
435_Y	438_L	0.503	0.98
125_F	181_Y	0.503	0.98
212_L	216_V	0.502	0.98
125_F	129_F	0.502	0.98
258_V	297_L	0.502	0.98
257_E	292_T	0.501	0.98
52_S	235_G	0.501	0.98
122_W	128_L	0.500	0.98
450_N	453_N	0.500	0.98
437_V	441_L	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4dgkA	1	0.7568	100	0.346	Contact Map
2yg5A	2	0.8359	100	0.376	Contact Map
4i59A	1	0.8359	100	0.381	Contact Map
4repA	1	0.9247	100	0.398	Contact Map
1s3eA	2	0.8533	100	0.408	Contact Map
2vvmA	2	0.8436	100	0.415	Contact Map
3i6dA	1	0.7915	100	0.425	Contact Map
2ivdA	1	0.8166	100	0.427	Contact Map
1b37A	4	0.832	100	0.434	Contact Map
1sezA	3	0.832	100	0.434	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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