Q97W21 - SULSO - GREMLIN Contacts

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Q97W21 - Methylmalonyl-CoA mutase, alpha-subunit, chain A (McmA1)

UniProt:	Q97W21	Sequences: MFIRFKHIMDVEDRIKEWEEKVYSSWVKKRGERKKEFKTFSGIHIKPVYTPLDVKGNYMEKLGLPGEYPFTRGIYPNMYRGRIWTIRQYAGFGSAEETNSRFRKLLEAGQTGLSMAFDLPTQLGLDPDHELAYTEIGVVGVSMFHWKEMDIVMSGIPLDKVTTSMTINATAMELLSMLIATSESRNINKSVLDGTVQNDILKEYIARKNFIYPPSPSMRYAIDIIEYSAKYLPKWHPISISGYHIREAGADAVLEVAFTLADGMEYVRKTMERGINVDEFAPHLSFFFAAYSDIFEEVAKFRAARRMWAKIMKEVFNAKKPESMMLRFHTQTGGAELTAQQPEINIIRTTLQALAAVLGGTQSLHVNSYDEALALPTEKAAKIAIRVQQIIANESGAADVVDPLGGSYYIEWLTDEIEERAWKIIDQVEKMGGMIKAIENGYPQAQIAESAYKIQKRIEEGDLGKVGVNMYYEPEWIGTTEIFRVNPEVRERVISRLKKYKQERDEMKLRESLNNLRKIAEKENENLFPYMIDAIRAGATVGETSGVLRDIWGEYKEPSIF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	561 (528)
Sequences:	2718 (1156)
Seq/√Len:	50.3

ECOLI - SCPA
HALSA - Q9HRZ1 Q9HRK7
SULSO - Q97W21

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
276_N	279_E	4.262	1.00
150_D	184_S	4.121	1.00
267_V	312_M	3.841	1.00
517_R	550_D	3.661	1.00
420_R	423_K	3.567	1.00
457_R	463_L	3.477	1.00
145_H	500_Y	3.449	1.00
251_D	450_S	3.356	1.00
183_E	536_R	3.306	1.00
127_P	144_F	3.030	1.00
271_M	277_V	3.014	1.00
288_F	304_A	2.931	1.00
310_K	422_W	2.922	1.00
127_P	142_S	2.897	1.00
346_I	383_I	2.873	1.00
98_T	102_F	2.850	1.00
295_F	409_Y	2.728	1.00
343_E	369_Y	2.722	1.00
278_D	319_K	2.674	1.00
46_K	53_D	2.659	1.00
505_D	508_K	2.594	1.00
506_E	510_R	2.515	1.00
240_I	284_L	2.498	1.00
499_K	503_E	2.490	1.00
281_A	312_M	2.487	1.00
268_R	429_E	2.479	1.00
415_D	419_E	2.465	1.00
520_A	548_L	2.465	1.00
180_A	536_R	2.460	1.00
393_N	471_Y	2.439	1.00
434_M	443_P	2.430	1.00
162_T	193_D	2.420	1.00
306_R	418_E	2.420	1.00
306_R	415_D	2.420	1.00
295_F	410_I	2.401	1.00
416_E	420_R	2.396	1.00
449_E	453_K	2.392	1.00
188_N	191_V	2.389	1.00
268_R	316_F	2.333	1.00
159_D	191_V	2.297	1.00
278_D	323_S	2.220	1.00
491_E	495_S	2.213	1.00
453_K	457_R	2.193	1.00
464_G	470_M	2.168	1.00
290_A	297_E	2.159	1.00
256_V	417_I	2.143	1.00
268_R	272_E	2.143	1.00
312_M	318_A	2.134	1.00
330_T	361_T	2.121	1.00
412_W	416_E	2.119	1.00
96_E	492_R	2.113	1.00
495_S	499_K	2.098	1.00
422_W	426_D	2.090	1.00
177_M	535_I	2.073	1.00
242_G	259_T	2.072	1.00
353_A	364_L	2.070	1.00
226_E	273_R	2.067	1.00
129_H	546_G	2.047	1.00
294_I	298_V	2.038	1.00
436_K	439_E	2.019	1.00
519_I	530_Y	2.005	1.00
319_K	323_S	1.995	1.00
262_D	434_M	1.993	1.00
264_M	425_I	1.991	1.00
71_T	306_R	1.979	1.00
427_Q	446_Q	1.956	0.99
529_P	533_D	1.917	0.99
254_L	446_Q	1.916	0.99
351_L	355_A	1.905	0.99
351_L	391_I	1.898	0.99
313_K	324_M	1.865	0.99
494_I	498_K	1.864	0.99
258_F	442_Y	1.851	0.99
281_A	323_S	1.840	0.99
343_E	379_K	1.808	0.99
461_G	470_M	1.808	0.99
454_I	463_L	1.799	0.99
159_D	187_I	1.789	0.99
288_F	301_F	1.784	0.99
157_P	160_K	1.776	0.99
344_I	390_I	1.758	0.99
510_R	514_N	1.757	0.99
548_L	552_W	1.755	0.99
515_N	533_D	1.730	0.99
41_S	296_E	1.719	0.99
346_I	369_Y	1.702	0.99
293_D	399_D	1.697	0.98
277_V	318_A	1.696	0.98
509_L	539_A	1.678	0.98
473_E	476_W	1.675	0.98
68_Y	309_A	1.674	0.98
535_I	544_T	1.668	0.98
512_S	537_A	1.661	0.98
183_E	189_K	1.652	0.98
150_D	538_G	1.652	0.98
257_A	424_I	1.648	0.98
276_N	319_K	1.645	0.98
226_E	230_K	1.640	0.98
36_E	44_H	1.605	0.98
329_H	363_S	1.604	0.98
431_M	442_Y	1.594	0.98
336_E	352_Q	1.572	0.97
256_V	421_A	1.571	0.97
228_S	237_P	1.563	0.97
146_W	538_G	1.553	0.97
184_S	538_G	1.548	0.97
145_H	540_T	1.540	0.97
255_E	300_K	1.540	0.97
353_A	391_I	1.528	0.97
103_R	155_G	1.525	0.97
86_I	385_I	1.515	0.97
46_K	49_Y	1.504	0.97
40_F	457_R	1.502	0.97
350_T	395_S	1.494	0.97
264_M	311_I	1.490	0.96
212_Y	545_S	1.490	0.96
189_K	231_Y	1.484	0.96
517_R	547_V	1.472	0.96
501_K	509_L	1.471	0.96
263_G	308_W	1.468	0.96
549_R	554_E	1.454	0.96
546_G	550_D	1.453	0.96
426_D	430_K	1.451	0.96
292_S	352_Q	1.445	0.96
424_I	427_Q	1.441	0.96
87_R	112_G	1.436	0.96
442_Y	446_Q	1.434	0.96
251_D	254_L	1.428	0.96
253_V	257_A	1.420	0.95
361_T	364_L	1.420	0.95
431_M	437_A	1.417	0.95
445_A	449_E	1.412	0.95
519_I	525_E	1.412	0.95
215_S	439_E	1.412	0.95
307_M	421_A	1.410	0.95
545_S	549_R	1.410	0.95
179_I	227_Y	1.405	0.95
68_Y	314_E	1.404	0.95
96_E	151_I	1.400	0.95
181_T	185_R	1.398	0.95
421_A	425_I	1.397	0.95
457_R	462_D	1.393	0.95
515_N	519_I	1.390	0.95
436_K	440_N	1.380	0.95
50_T	53_D	1.373	0.94
264_M	316_F	1.372	0.94
260_L	307_M	1.363	0.94
424_I	442_Y	1.361	0.94
377_T	380_A	1.359	0.94
61_K	415_D	1.358	0.94
260_L	263_G	1.350	0.94
45_I	409_Y	1.341	0.94
260_L	311_I	1.340	0.94
222_I	269_K	1.338	0.94
347_I	350_T	1.329	0.93
357_V	364_L	1.325	0.93
259_T	288_F	1.321	0.93
43_I	420_R	1.306	0.93
488_E	492_R	1.302	0.93
419_E	423_K	1.294	0.92
382_K	473_E	1.290	0.92
292_S	336_E	1.282	0.92
254_L	424_I	1.277	0.92
147_K	150_D	1.274	0.92
424_I	446_Q	1.273	0.92
269_K	272_E	1.272	0.92
99_N	155_G	1.272	0.92
85_T	112_G	1.270	0.92
225_I	270_T	1.266	0.92
39_T	45_I	1.263	0.92
265_E	269_K	1.260	0.91
516_L	534_A	1.260	0.91
201_L	266_Y	1.259	0.91
178_L	182_S	1.253	0.91
382_K	386_R	1.252	0.91
104_K	378_E	1.249	0.91
490_R	494_I	1.248	0.91
514_N	518_K	1.244	0.91
278_D	281_A	1.237	0.91
508_K	512_S	1.236	0.91
358_L	404_L	1.236	0.91
102_F	115_M	1.235	0.91
534_A	539_A	1.234	0.91
517_R	522_K	1.233	0.91
38_K	44_H	1.233	0.91
99_N	103_R	1.232	0.90
23_Y	27_V	1.232	0.90
97_E	100_S	1.221	0.90
189_K	227_Y	1.215	0.90
172_M	548_L	1.214	0.90
49_Y	412_W	1.213	0.90
261_A	425_I	1.211	0.90
219_R	552_W	1.208	0.90
423_K	426_D	1.199	0.89
508_K	537_A	1.192	0.89
427_Q	431_M	1.189	0.89
246_R	333_G	1.188	0.89
230_K	279_E	1.186	0.89
492_R	495_S	1.185	0.89
294_I	354_L	1.183	0.89
446_Q	449_E	1.181	0.89
309_A	324_M	1.177	0.88
96_E	100_S	1.176	0.88
102_F	113_L	1.171	0.88
265_E	435_I	1.165	0.88
500_Y	538_G	1.163	0.88
49_Y	409_Y	1.156	0.87
508_K	533_D	1.156	0.87
253_V	420_R	1.140	0.87
368_S	381_A	1.140	0.87
104_K	107_E	1.132	0.86
147_K	538_G	1.131	0.86
66_G	70_F	1.129	0.86
511_E	533_D	1.129	0.86
195_T	285_S	1.125	0.86
86_I	389_Q	1.121	0.86
290_A	330_T	1.120	0.86
177_M	541_V	1.119	0.86
349_T	352_Q	1.117	0.86
309_A	313_K	1.112	0.85
179_I	189_K	1.110	0.85
103_R	107_E	1.106	0.85
506_E	509_L	1.106	0.85
523_E	527_L	1.105	0.85
147_K	500_Y	1.105	0.85
354_L	358_L	1.104	0.85
282_P	323_S	1.102	0.85
437_A	443_P	1.100	0.85
37_F	45_I	1.098	0.85
517_R	551_I	1.097	0.85
522_K	525_E	1.096	0.84
546_G	549_R	1.096	0.84
245_I	262_D	1.093	0.84
533_D	536_R	1.086	0.84
400_V	405_G	1.084	0.84
531_M	544_T	1.081	0.84
437_A	442_Y	1.080	0.84
307_M	422_W	1.075	0.83
149_M	181_T	1.075	0.83
40_F	463_L	1.073	0.83
49_Y	53_D	1.073	0.83
146_W	150_D	1.072	0.83
64_L	67_E	1.069	0.83
355_A	358_L	1.062	0.83
27_V	30_R	1.062	0.83
179_I	532_I	1.059	0.82
89_Y	116_A	1.059	0.82
464_G	469_N	1.052	0.82
427_Q	430_K	1.048	0.82
122_Q	207_R	1.046	0.82
35_K	47_P	1.044	0.81
163_T	178_L	1.044	0.81
516_L	530_Y	1.043	0.81
411_E	414_T	1.034	0.81
288_F	328_F	1.032	0.81
205_I	208_K	1.030	0.81
43_I	295_F	1.027	0.80
225_I	273_R	1.025	0.80
119_L	122_Q	1.025	0.80
66_G	73_G	1.023	0.80
492_R	498_K	1.017	0.80
288_F	330_T	1.016	0.80
48_V	64_L	1.016	0.80
115_M	152_V	1.014	0.80
222_I	273_R	1.012	0.79
497_L	500_Y	1.011	0.79
528_F	532_I	1.008	0.79
507_M	511_E	1.005	0.79
278_D	318_A	1.004	0.79
293_D	463_L	1.004	0.79
242_G	288_F	1.002	0.79
23_Y	30_R	1.002	0.79
518_K	525_E	0.999	0.78
225_I	238_I	0.998	0.78
404_L	410_I	0.995	0.78
351_L	395_S	0.994	0.78
290_A	301_F	0.987	0.78
531_M	535_I	0.985	0.77
336_E	349_T	0.983	0.77
374_A	377_T	0.981	0.77
265_E	268_R	0.977	0.77
115_M	153_M	0.973	0.77
298_V	358_L	0.972	0.77
225_I	237_P	0.970	0.76
194_G	235_W	0.967	0.76
491_E	498_K	0.966	0.76
47_P	77_N	0.965	0.76
66_G	72_R	0.965	0.76
547_V	551_I	0.963	0.76
90_A	98_T	0.961	0.76
294_I	391_I	0.955	0.75
71_T	418_E	0.954	0.75
151_I	154_S	0.951	0.75
89_Y	207_R	0.949	0.75
357_V	397_A	0.949	0.75
456_K	460_E	0.946	0.75
177_M	544_T	0.938	0.74
515_N	530_Y	0.932	0.73
512_S	515_N	0.932	0.73
286_F	326_L	0.932	0.73
304_A	326_L	0.931	0.73
514_N	517_R	0.926	0.73
68_Y	310_K	0.925	0.73
176_S	227_Y	0.924	0.73
241_S	259_T	0.922	0.73
141_V	152_V	0.922	0.73
145_H	501_K	0.918	0.72
127_P	493_V	0.917	0.72
252_A	296_E	0.912	0.72
196_V	237_P	0.910	0.72
89_Y	122_Q	0.909	0.72
498_K	502_Q	0.907	0.71
261_A	428_V	0.904	0.71
427_Q	442_Y	0.904	0.71
98_T	152_V	0.903	0.71
193_D	234_K	0.900	0.71
350_T	360_G	0.898	0.71
173_E	545_S	0.897	0.71
172_M	531_M	0.897	0.71
354_L	397_A	0.897	0.71
424_I	428_V	0.896	0.70
396_G	399_D	0.894	0.70
201_L	434_M	0.894	0.70
96_E	154_S	0.892	0.70
29_K	34_K	0.890	0.70
461_G	464_G	0.887	0.70
250_A	447_I	0.886	0.70
72_R	405_G	0.882	0.69
318_A	323_S	0.878	0.69
516_L	548_L	0.876	0.69
23_Y	28_K	0.873	0.68
65_P	72_R	0.872	0.68
170_T	173_E	0.870	0.68
87_R	164_S	0.870	0.68
63_G	306_R	0.869	0.68
295_F	404_L	0.864	0.68
43_I	416_E	0.862	0.67
30_R	33_R	0.862	0.67
332_T	366_V	0.859	0.67
533_D	537_A	0.859	0.67
497_L	540_T	0.857	0.67
41_S	252_A	0.856	0.67
254_L	450_S	0.856	0.67
306_R	309_A	0.856	0.67
331_Q	367_N	0.855	0.67
87_R	363_S	0.855	0.67
440_N	445_A	0.854	0.67
54_V	408_Y	0.851	0.66
444_Q	448_A	0.848	0.66
416_E	419_E	0.845	0.66
122_Q	208_K	0.843	0.66
164_S	195_T	0.843	0.66
369_Y	379_K	0.839	0.65
498_K	501_K	0.838	0.65
158_L	163_T	0.837	0.65
142_S	148_E	0.835	0.65
201_L	435_I	0.835	0.65
122_Q	139_V	0.834	0.65
519_I	522_K	0.832	0.65
252_A	291_Y	0.830	0.65
518_K	522_K	0.830	0.65
335_A	458_I	0.829	0.64
341_Q	386_R	0.828	0.64
530_Y	534_A	0.827	0.64
227_Y	232_L	0.827	0.64
245_I	447_I	0.824	0.64
389_Q	393_N	0.824	0.64
496_R	499_K	0.823	0.64
205_I	438_I	0.823	0.64
425_I	429_E	0.822	0.64
301_F	330_T	0.820	0.64
119_L	210_F	0.820	0.64
48_V	401_V	0.817	0.63
26_W	30_R	0.817	0.63
512_S	533_D	0.817	0.63
240_I	267_V	0.815	0.63
455_Q	496_R	0.814	0.63
222_I	226_E	0.814	0.63
295_F	413_L	0.813	0.63
179_I	232_L	0.812	0.63
139_V	208_K	0.812	0.63
105_L	110_Q	0.811	0.63
215_S	436_K	0.811	0.63
386_R	389_Q	0.810	0.63
252_A	417_I	0.810	0.63
221_A	238_I	0.809	0.63
289_A	335_A	0.809	0.63
501_K	540_T	0.808	0.62
458_I	465_K	0.808	0.62
400_V	409_Y	0.807	0.62
258_F	434_M	0.802	0.62
103_R	154_S	0.802	0.62
182_S	192_L	0.797	0.61
189_K	532_I	0.797	0.61
105_L	381_A	0.796	0.61
404_L	409_Y	0.794	0.61
509_L	537_A	0.792	0.61
366_V	388_Q	0.790	0.61
311_I	422_W	0.785	0.60
87_R	114_S	0.784	0.60
150_D	185_R	0.782	0.60
367_N	371_E	0.781	0.60
278_D	282_P	0.781	0.60
257_A	421_A	0.777	0.59
318_A	324_M	0.775	0.59
100_S	107_E	0.774	0.59
357_V	391_I	0.774	0.59
147_K	503_E	0.773	0.59
151_I	496_R	0.770	0.59
519_I	552_W	0.769	0.59
374_A	482_I	0.768	0.59
21_K	24_S	0.768	0.59
63_G	71_T	0.767	0.58
250_A	289_A	0.763	0.58
486_N	489_V	0.762	0.58
253_V	417_I	0.761	0.58
488_E	498_K	0.761	0.58
60_E	63_G	0.760	0.58
243_Y	331_Q	0.760	0.58
415_D	423_K	0.759	0.58
525_E	528_F	0.758	0.58
440_N	443_P	0.756	0.57
39_T	43_I	0.754	0.57
236_H	283_H	0.751	0.57
423_K	427_Q	0.751	0.57
52_L	55_K	0.749	0.57
488_E	491_E	0.749	0.57
87_R	194_G	0.748	0.57
517_R	555_Y	0.748	0.57
258_F	424_I	0.745	0.56
403_P	410_I	0.745	0.56
260_L	425_I	0.742	0.56
102_F	156_I	0.742	0.56
349_T	367_N	0.742	0.56
455_Q	459_E	0.741	0.56
66_G	69_P	0.740	0.56
139_V	209_N	0.732	0.55
146_W	500_Y	0.731	0.55
492_R	546_G	0.728	0.54
295_F	407_S	0.727	0.54
286_F	308_W	0.726	0.54
517_R	525_E	0.725	0.54
494_I	501_K	0.722	0.54
392_A	398_A	0.721	0.54
257_A	446_Q	0.721	0.54
291_Y	297_E	0.720	0.54
93_G	98_T	0.719	0.54
451_A	455_Q	0.718	0.53
312_M	324_M	0.718	0.53
20_E	24_S	0.718	0.53
104_K	108_A	0.718	0.53
246_R	252_A	0.716	0.53
310_K	418_E	0.715	0.53
60_E	405_G	0.715	0.53
166_T	202_K	0.714	0.53
281_A	318_A	0.714	0.53
150_D	180_A	0.712	0.53
33_R	36_E	0.712	0.53
146_W	184_S	0.712	0.53
170_T	545_S	0.711	0.53
112_G	195_T	0.710	0.53
472_Y	476_W	0.710	0.53
341_Q	382_K	0.710	0.53
397_A	501_K	0.709	0.53
25_S	28_K	0.709	0.53
334_G	371_E	0.709	0.53
289_A	300_K	0.707	0.52
239_S	287_F	0.707	0.52
417_I	421_A	0.706	0.52
32_E	37_F	0.702	0.52
329_H	365_H	0.700	0.52
100_S	104_K	0.699	0.51
358_L	397_A	0.697	0.51
230_K	508_K	0.696	0.51
299_A	413_L	0.695	0.51
498_K	525_E	0.695	0.51
221_A	225_I	0.694	0.51
25_S	30_R	0.694	0.51
267_V	308_W	0.693	0.51
507_M	510_R	0.692	0.51
528_F	531_M	0.692	0.51
101_R	105_L	0.691	0.51
183_E	187_I	0.691	0.51
23_Y	26_W	0.691	0.51
515_N	525_E	0.690	0.51
29_K	32_E	0.689	0.50
314_E	318_A	0.689	0.50
94_S	97_E	0.688	0.50
343_E	346_I	0.688	0.50
202_K	244_H	0.688	0.50
290_A	328_F	0.685	0.50
194_G	233_P	0.684	0.50
68_Y	313_K	0.684	0.50
225_I	435_I	0.684	0.50
252_A	354_L	0.684	0.50
212_Y	548_L	0.683	0.50
68_Y	324_M	0.683	0.50
335_A	493_V	0.682	0.50
263_G	286_F	0.682	0.50
497_L	501_K	0.680	0.50
245_I	434_M	0.680	0.50
50_T	64_L	0.680	0.50
503_E	517_R	0.679	0.49
221_A	224_I	0.678	0.49
150_D	177_M	0.677	0.49
338_T	494_I	0.674	0.49
297_E	352_Q	0.674	0.49
46_K	412_W	0.674	0.49
94_S	441_G	0.673	0.49
306_R	310_K	0.673	0.49
65_P	70_F	0.673	0.49
220_Y	224_I	0.672	0.49
353_A	366_V	0.672	0.49
360_G	403_P	0.672	0.49
291_Y	333_G	0.672	0.49
69_P	73_G	0.669	0.48
70_F	73_G	0.668	0.48
270_T	273_R	0.666	0.48
267_V	280_F	0.666	0.48
203_E	207_R	0.665	0.48
225_I	283_H	0.665	0.48
218_M	221_A	0.665	0.48
253_V	424_I	0.665	0.48
119_L	207_R	0.664	0.48
260_L	326_L	0.663	0.48
265_E	434_M	0.662	0.48
258_F	428_V	0.660	0.47
510_R	539_A	0.657	0.47
125_L	131_L	0.657	0.47
129_H	133_Y	0.657	0.47
287_F	331_Q	0.655	0.47
89_Y	209_N	0.654	0.47
338_T	344_I	0.654	0.47
89_Y	114_S	0.650	0.46
196_V	224_I	0.649	0.46
246_R	255_E	0.648	0.46
445_A	465_K	0.647	0.46
277_V	323_S	0.646	0.46
501_K	516_L	0.643	0.46
129_H	549_R	0.643	0.46
90_A	102_F	0.639	0.45
522_K	551_I	0.638	0.45
341_Q	473_E	0.637	0.45
488_E	525_E	0.636	0.45
65_P	294_I	0.636	0.45
89_Y	119_L	0.633	0.45
264_M	268_R	0.632	0.45
122_Q	209_N	0.631	0.45
33_R	37_F	0.631	0.45
246_R	291_Y	0.629	0.44
310_K	313_K	0.628	0.44
111_T	160_K	0.627	0.44
422_W	425_I	0.627	0.44
537_A	541_V	0.626	0.44
240_I	259_T	0.626	0.44
146_W	177_M	0.625	0.44
41_S	293_D	0.625	0.44
87_R	285_S	0.624	0.44
227_Y	231_Y	0.623	0.44
314_E	317_N	0.623	0.44
183_E	188_N	0.621	0.44
494_I	500_Y	0.619	0.43
101_R	381_A	0.619	0.43
271_M	316_F	0.619	0.43
482_I	485_V	0.618	0.43
241_S	287_F	0.617	0.43
158_L	185_R	0.617	0.43
233_P	407_S	0.616	0.43
511_E	517_R	0.615	0.43
350_T	463_L	0.615	0.43
45_I	400_V	0.614	0.43
176_S	180_A	0.614	0.43
288_F	326_L	0.614	0.43
473_E	477_I	0.613	0.43
341_Q	476_W	0.613	0.43
64_L	76_P	0.613	0.43
343_E	347_I	0.612	0.43
412_W	415_D	0.612	0.43
256_V	295_F	0.611	0.43
307_M	311_I	0.611	0.43
369_Y	399_D	0.611	0.43
190_S	231_Y	0.607	0.42
320_K	439_E	0.606	0.42
22_V	27_V	0.606	0.42
41_S	251_D	0.606	0.42
332_T	364_L	0.606	0.42
47_P	476_W	0.604	0.42
267_V	277_V	0.604	0.42
21_K	25_S	0.604	0.42
466_V	472_Y	0.604	0.42
264_M	317_N	0.604	0.42
106_L	157_P	0.603	0.42
39_T	252_A	0.603	0.42
390_I	464_G	0.603	0.42
164_S	194_G	0.602	0.42
519_I	523_E	0.602	0.42
73_G	405_G	0.600	0.41
500_Y	503_E	0.600	0.41
511_E	515_N	0.600	0.41
472_Y	475_E	0.597	0.41
202_K	205_I	0.596	0.41
298_V	410_I	0.595	0.41
515_N	518_K	0.592	0.41
114_S	388_Q	0.592	0.41
241_S	367_N	0.592	0.41
292_S	390_I	0.591	0.41
49_Y	295_F	0.590	0.40
279_E	282_P	0.590	0.40
532_I	536_R	0.590	0.40
236_H	327_R	0.589	0.40
343_E	383_I	0.589	0.40
88_Q	110_Q	0.588	0.40
243_Y	247_E	0.587	0.40
522_K	536_R	0.586	0.40
431_M	440_N	0.586	0.40
83_I	86_I	0.585	0.40
279_E	323_S	0.585	0.40
382_K	476_W	0.584	0.40
150_D	181_T	0.584	0.40
42_G	494_I	0.583	0.40
95_A	152_V	0.583	0.40
173_E	544_T	0.582	0.40
502_Q	507_M	0.582	0.40
178_L	235_W	0.581	0.40
99_N	152_V	0.580	0.39
512_S	524_N	0.580	0.39
200_I	212_Y	0.580	0.39
504_R	507_M	0.578	0.39
223_D	227_Y	0.578	0.39
264_M	318_A	0.578	0.39
64_L	401_V	0.576	0.39
285_S	329_H	0.576	0.39
129_H	542_G	0.576	0.39
329_H	384_A	0.574	0.39
350_T	390_I	0.573	0.39
488_E	495_S	0.573	0.39
407_S	410_I	0.573	0.39
453_K	456_K	0.573	0.39
271_M	276_N	0.572	0.39
532_I	535_I	0.572	0.39
500_Y	509_L	0.571	0.39
357_V	392_A	0.570	0.38
319_K	324_M	0.570	0.38
487_P	492_R	0.570	0.38
461_G	472_Y	0.570	0.38
105_L	385_I	0.569	0.38
254_L	443_P	0.569	0.38
351_L	354_L	0.568	0.38
113_L	166_T	0.566	0.38
501_K	542_G	0.566	0.38
417_I	424_I	0.565	0.38
271_M	318_A	0.565	0.38
360_G	405_G	0.565	0.38
149_M	178_L	0.565	0.38
340_Q	468_V	0.564	0.38
74_I	405_G	0.564	0.38
311_I	555_Y	0.563	0.38
20_E	23_Y	0.563	0.38
39_T	296_E	0.562	0.38
525_E	550_D	0.561	0.38
511_E	537_A	0.561	0.38
267_V	316_F	0.560	0.37
431_M	446_Q	0.559	0.37
514_N	525_E	0.559	0.37
304_A	328_F	0.559	0.37
337_L	376_P	0.557	0.37
525_E	529_P	0.557	0.37
70_F	477_I	0.556	0.37
511_E	514_N	0.556	0.37
331_Q	365_H	0.554	0.37
22_V	32_E	0.554	0.37
320_K	324_M	0.553	0.37
98_T	115_M	0.552	0.37
179_I	465_K	0.552	0.37
225_I	280_F	0.551	0.37
147_K	555_Y	0.550	0.37
260_L	264_M	0.550	0.37
116_A	166_T	0.549	0.36
450_S	454_I	0.548	0.36
400_V	403_P	0.548	0.36
368_S	548_L	0.547	0.36
527_L	548_L	0.547	0.36
41_S	341_Q	0.546	0.36
101_R	104_K	0.546	0.36
436_K	498_K	0.545	0.36
290_A	355_A	0.543	0.36
292_S	395_S	0.542	0.36
409_Y	413_L	0.542	0.36
153_M	175_L	0.542	0.36
245_I	259_T	0.542	0.36
382_K	501_K	0.539	0.35
215_S	218_M	0.539	0.35
517_R	533_D	0.539	0.35
61_K	64_L	0.538	0.35
121_T	174_L	0.538	0.35
258_F	446_Q	0.537	0.35
75_Y	460_E	0.537	0.35
34_K	56_G	0.537	0.35
480_T	488_E	0.536	0.35
275_I	279_E	0.536	0.35
167_I	171_A	0.535	0.35
159_D	188_N	0.534	0.35
498_K	517_R	0.534	0.35
87_R	195_T	0.533	0.35
123_L	554_E	0.532	0.35
256_V	307_M	0.532	0.35
147_K	499_K	0.532	0.35
502_Q	514_N	0.531	0.35
28_K	35_K	0.529	0.35
85_T	195_T	0.529	0.35
508_K	511_E	0.528	0.34
242_G	245_I	0.527	0.34
492_R	532_I	0.527	0.34
114_S	365_H	0.527	0.34
425_I	541_V	0.526	0.34
189_K	536_R	0.526	0.34
476_W	479_T	0.526	0.34
337_L	352_Q	0.525	0.34
96_E	130_E	0.525	0.34
144_F	493_V	0.525	0.34
75_Y	377_T	0.525	0.34
291_Y	352_Q	0.524	0.34
493_V	496_R	0.524	0.34
212_Y	417_I	0.524	0.34
22_V	25_S	0.523	0.34
525_E	537_A	0.522	0.34
243_Y	334_G	0.521	0.34
60_E	415_D	0.521	0.34
322_E	325_M	0.521	0.34
383_I	552_W	0.521	0.34
317_N	320_K	0.521	0.34
267_V	271_M	0.521	0.34
103_R	157_P	0.521	0.34
338_T	465_K	0.521	0.34
155_G	317_N	0.521	0.34
498_K	550_D	0.520	0.34
282_P	311_I	0.519	0.34
110_Q	405_G	0.519	0.34
56_G	412_W	0.519	0.34
43_I	296_E	0.519	0.34
544_T	550_D	0.518	0.34
454_I	458_I	0.518	0.34
86_I	392_A	0.518	0.34
239_S	285_S	0.517	0.33
242_G	262_D	0.516	0.33
547_V	550_D	0.516	0.33
337_L	349_T	0.515	0.33
418_E	422_W	0.515	0.33
363_S	384_A	0.514	0.33
277_V	316_F	0.514	0.33
510_R	515_N	0.514	0.33
41_S	386_R	0.514	0.33
152_V	251_D	0.513	0.33
512_S	534_A	0.513	0.33
39_T	42_G	0.513	0.33
252_A	255_E	0.513	0.33
219_R	273_R	0.513	0.33
204_Y	439_E	0.513	0.33
35_K	64_L	0.512	0.33
26_W	34_K	0.512	0.33
26_W	29_K	0.512	0.33
498_K	546_G	0.511	0.33
491_E	499_K	0.511	0.33
71_T	414_T	0.511	0.33
122_Q	135_E	0.511	0.33
40_F	450_S	0.510	0.33
250_A	369_Y	0.510	0.33
197_Q	287_F	0.509	0.33
74_I	325_M	0.509	0.33
46_K	541_V	0.509	0.33
205_I	245_I	0.508	0.33
219_R	278_D	0.507	0.33
419_E	550_D	0.507	0.33
226_E	269_K	0.507	0.33
259_T	326_L	0.507	0.33
492_R	497_L	0.505	0.32
294_I	352_Q	0.505	0.32
78_M	401_V	0.505	0.32
77_N	81_G	0.505	0.32
391_I	476_W	0.505	0.32
324_M	551_I	0.504	0.32
272_E	430_K	0.504	0.32
297_E	300_K	0.504	0.32
165_M	174_L	0.503	0.32
93_G	318_A	0.501	0.32
389_Q	392_A	0.501	0.32
517_R	528_F	0.501	0.32
170_T	212_Y	0.501	0.32
296_E	341_Q	0.500	0.32
215_S	273_R	0.500	0.32
517_R	532_I	0.500	0.32
466_V	470_M	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r3uA	2	0.9911	100	0.069	Contact Map
2xijA	2	0.9733	100	0.089	Contact Map
1reqA	1	0.9857	100	0.098	Contact Map
4xc8A	2	0.975	100	0.153	Contact Map
1reqB	1	0.9216	100	0.216	Contact Map
3kp1A	2	0.8895	100	0.475	Contact Map
1ccwB	2	0.7861	100	0.803	Contact Map
3oa3A	2	0.3939	67	0.978	Contact Map
2yciX	2	0.4724	45.1	0.981	Contact Map
3bijA	5	0.1355	29.3	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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