GREMLIN Database
Q97W21 - Methylmalonyl-CoA mutase, alpha-subunit, chain A (McmA1)
UniProt: Q97W21 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 561 (528)
Sequences: 2718 (1156)
Seq/√Len: 50.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
276_N279_E4.2621.00
150_D184_S4.1211.00
267_V312_M3.8411.00
517_R550_D3.6611.00
420_R423_K3.5671.00
457_R463_L3.4771.00
145_H500_Y3.4491.00
251_D450_S3.3561.00
183_E536_R3.3061.00
127_P144_F3.0301.00
271_M277_V3.0141.00
288_F304_A2.9311.00
310_K422_W2.9221.00
127_P142_S2.8971.00
346_I383_I2.8731.00
98_T102_F2.8501.00
295_F409_Y2.7281.00
343_E369_Y2.7221.00
278_D319_K2.6741.00
46_K53_D2.6591.00
505_D508_K2.5941.00
506_E510_R2.5151.00
240_I284_L2.4981.00
499_K503_E2.4901.00
281_A312_M2.4871.00
268_R429_E2.4791.00
415_D419_E2.4651.00
520_A548_L2.4651.00
180_A536_R2.4601.00
393_N471_Y2.4391.00
434_M443_P2.4301.00
162_T193_D2.4201.00
306_R418_E2.4201.00
306_R415_D2.4201.00
295_F410_I2.4011.00
416_E420_R2.3961.00
449_E453_K2.3921.00
188_N191_V2.3891.00
268_R316_F2.3331.00
159_D191_V2.2971.00
278_D323_S2.2201.00
491_E495_S2.2131.00
453_K457_R2.1931.00
464_G470_M2.1681.00
290_A297_E2.1591.00
256_V417_I2.1431.00
268_R272_E2.1431.00
312_M318_A2.1341.00
330_T361_T2.1211.00
412_W416_E2.1191.00
96_E492_R2.1131.00
495_S499_K2.0981.00
422_W426_D2.0901.00
177_M535_I2.0731.00
242_G259_T2.0721.00
353_A364_L2.0701.00
226_E273_R2.0671.00
129_H546_G2.0471.00
294_I298_V2.0381.00
436_K439_E2.0191.00
519_I530_Y2.0051.00
319_K323_S1.9951.00
262_D434_M1.9931.00
264_M425_I1.9911.00
71_T306_R1.9791.00
427_Q446_Q1.9560.99
529_P533_D1.9170.99
254_L446_Q1.9160.99
351_L355_A1.9050.99
351_L391_I1.8980.99
313_K324_M1.8650.99
494_I498_K1.8640.99
258_F442_Y1.8510.99
281_A323_S1.8400.99
343_E379_K1.8080.99
461_G470_M1.8080.99
454_I463_L1.7990.99
159_D187_I1.7890.99
288_F301_F1.7840.99
157_P160_K1.7760.99
344_I390_I1.7580.99
510_R514_N1.7570.99
548_L552_W1.7550.99
515_N533_D1.7300.99
41_S296_E1.7190.99
346_I369_Y1.7020.99
293_D399_D1.6970.98
277_V318_A1.6960.98
509_L539_A1.6780.98
473_E476_W1.6750.98
68_Y309_A1.6740.98
535_I544_T1.6680.98
512_S537_A1.6610.98
183_E189_K1.6520.98
150_D538_G1.6520.98
257_A424_I1.6480.98
276_N319_K1.6450.98
226_E230_K1.6400.98
36_E44_H1.6050.98
329_H363_S1.6040.98
431_M442_Y1.5940.98
336_E352_Q1.5720.97
256_V421_A1.5710.97
228_S237_P1.5630.97
146_W538_G1.5530.97
184_S538_G1.5480.97
145_H540_T1.5400.97
255_E300_K1.5400.97
353_A391_I1.5280.97
103_R155_G1.5250.97
86_I385_I1.5150.97
46_K49_Y1.5040.97
40_F457_R1.5020.97
350_T395_S1.4940.97
264_M311_I1.4900.96
212_Y545_S1.4900.96
189_K231_Y1.4840.96
517_R547_V1.4720.96
501_K509_L1.4710.96
263_G308_W1.4680.96
549_R554_E1.4540.96
546_G550_D1.4530.96
426_D430_K1.4510.96
292_S352_Q1.4450.96
424_I427_Q1.4410.96
87_R112_G1.4360.96
442_Y446_Q1.4340.96
251_D254_L1.4280.96
253_V257_A1.4200.95
361_T364_L1.4200.95
431_M437_A1.4170.95
445_A449_E1.4120.95
519_I525_E1.4120.95
215_S439_E1.4120.95
307_M421_A1.4100.95
545_S549_R1.4100.95
179_I227_Y1.4050.95
68_Y314_E1.4040.95
96_E151_I1.4000.95
181_T185_R1.3980.95
421_A425_I1.3970.95
457_R462_D1.3930.95
515_N519_I1.3900.95
436_K440_N1.3800.95
50_T53_D1.3730.94
264_M316_F1.3720.94
260_L307_M1.3630.94
424_I442_Y1.3610.94
377_T380_A1.3590.94
61_K415_D1.3580.94
260_L263_G1.3500.94
45_I409_Y1.3410.94
260_L311_I1.3400.94
222_I269_K1.3380.94
347_I350_T1.3290.93
357_V364_L1.3250.93
259_T288_F1.3210.93
43_I420_R1.3060.93
488_E492_R1.3020.93
419_E423_K1.2940.92
382_K473_E1.2900.92
292_S336_E1.2820.92
254_L424_I1.2770.92
147_K150_D1.2740.92
424_I446_Q1.2730.92
269_K272_E1.2720.92
99_N155_G1.2720.92
85_T112_G1.2700.92
225_I270_T1.2660.92
39_T45_I1.2630.92
265_E269_K1.2600.91
516_L534_A1.2600.91
201_L266_Y1.2590.91
178_L182_S1.2530.91
382_K386_R1.2520.91
104_K378_E1.2490.91
490_R494_I1.2480.91
514_N518_K1.2440.91
278_D281_A1.2370.91
508_K512_S1.2360.91
358_L404_L1.2360.91
102_F115_M1.2350.91
534_A539_A1.2340.91
517_R522_K1.2330.91
38_K44_H1.2330.91
99_N103_R1.2320.90
23_Y27_V1.2320.90
97_E100_S1.2210.90
189_K227_Y1.2150.90
172_M548_L1.2140.90
49_Y412_W1.2130.90
261_A425_I1.2110.90
219_R552_W1.2080.90
423_K426_D1.1990.89
508_K537_A1.1920.89
427_Q431_M1.1890.89
246_R333_G1.1880.89
230_K279_E1.1860.89
492_R495_S1.1850.89
294_I354_L1.1830.89
446_Q449_E1.1810.89
309_A324_M1.1770.88
96_E100_S1.1760.88
102_F113_L1.1710.88
265_E435_I1.1650.88
500_Y538_G1.1630.88
49_Y409_Y1.1560.87
508_K533_D1.1560.87
253_V420_R1.1400.87
368_S381_A1.1400.87
104_K107_E1.1320.86
147_K538_G1.1310.86
66_G70_F1.1290.86
511_E533_D1.1290.86
195_T285_S1.1250.86
86_I389_Q1.1210.86
290_A330_T1.1200.86
177_M541_V1.1190.86
349_T352_Q1.1170.86
309_A313_K1.1120.85
179_I189_K1.1100.85
103_R107_E1.1060.85
506_E509_L1.1060.85
523_E527_L1.1050.85
147_K500_Y1.1050.85
354_L358_L1.1040.85
282_P323_S1.1020.85
437_A443_P1.1000.85
37_F45_I1.0980.85
517_R551_I1.0970.85
522_K525_E1.0960.84
546_G549_R1.0960.84
245_I262_D1.0930.84
533_D536_R1.0860.84
400_V405_G1.0840.84
531_M544_T1.0810.84
437_A442_Y1.0800.84
307_M422_W1.0750.83
149_M181_T1.0750.83
40_F463_L1.0730.83
49_Y53_D1.0730.83
146_W150_D1.0720.83
64_L67_E1.0690.83
355_A358_L1.0620.83
27_V30_R1.0620.83
179_I532_I1.0590.82
89_Y116_A1.0590.82
464_G469_N1.0520.82
427_Q430_K1.0480.82
122_Q207_R1.0460.82
35_K47_P1.0440.81
163_T178_L1.0440.81
516_L530_Y1.0430.81
411_E414_T1.0340.81
288_F328_F1.0320.81
205_I208_K1.0300.81
43_I295_F1.0270.80
225_I273_R1.0250.80
119_L122_Q1.0250.80
66_G73_G1.0230.80
492_R498_K1.0170.80
288_F330_T1.0160.80
48_V64_L1.0160.80
115_M152_V1.0140.80
222_I273_R1.0120.79
497_L500_Y1.0110.79
528_F532_I1.0080.79
507_M511_E1.0050.79
278_D318_A1.0040.79
293_D463_L1.0040.79
242_G288_F1.0020.79
23_Y30_R1.0020.79
518_K525_E0.9990.78
225_I238_I0.9980.78
404_L410_I0.9950.78
351_L395_S0.9940.78
290_A301_F0.9870.78
531_M535_I0.9850.77
336_E349_T0.9830.77
374_A377_T0.9810.77
265_E268_R0.9770.77
115_M153_M0.9730.77
298_V358_L0.9720.77
225_I237_P0.9700.76
194_G235_W0.9670.76
491_E498_K0.9660.76
47_P77_N0.9650.76
66_G72_R0.9650.76
547_V551_I0.9630.76
90_A98_T0.9610.76
294_I391_I0.9550.75
71_T418_E0.9540.75
151_I154_S0.9510.75
89_Y207_R0.9490.75
357_V397_A0.9490.75
456_K460_E0.9460.75
177_M544_T0.9380.74
515_N530_Y0.9320.73
512_S515_N0.9320.73
286_F326_L0.9320.73
304_A326_L0.9310.73
514_N517_R0.9260.73
68_Y310_K0.9250.73
176_S227_Y0.9240.73
241_S259_T0.9220.73
141_V152_V0.9220.73
145_H501_K0.9180.72
127_P493_V0.9170.72
252_A296_E0.9120.72
196_V237_P0.9100.72
89_Y122_Q0.9090.72
498_K502_Q0.9070.71
261_A428_V0.9040.71
427_Q442_Y0.9040.71
98_T152_V0.9030.71
193_D234_K0.9000.71
350_T360_G0.8980.71
173_E545_S0.8970.71
172_M531_M0.8970.71
354_L397_A0.8970.71
424_I428_V0.8960.70
396_G399_D0.8940.70
201_L434_M0.8940.70
96_E154_S0.8920.70
29_K34_K0.8900.70
461_G464_G0.8870.70
250_A447_I0.8860.70
72_R405_G0.8820.69
318_A323_S0.8780.69
516_L548_L0.8760.69
23_Y28_K0.8730.68
65_P72_R0.8720.68
170_T173_E0.8700.68
87_R164_S0.8700.68
63_G306_R0.8690.68
295_F404_L0.8640.68
43_I416_E0.8620.67
30_R33_R0.8620.67
332_T366_V0.8590.67
533_D537_A0.8590.67
497_L540_T0.8570.67
41_S252_A0.8560.67
254_L450_S0.8560.67
306_R309_A0.8560.67
331_Q367_N0.8550.67
87_R363_S0.8550.67
440_N445_A0.8540.67
54_V408_Y0.8510.66
444_Q448_A0.8480.66
416_E419_E0.8450.66
122_Q208_K0.8430.66
164_S195_T0.8430.66
369_Y379_K0.8390.65
498_K501_K0.8380.65
158_L163_T0.8370.65
142_S148_E0.8350.65
201_L435_I0.8350.65
122_Q139_V0.8340.65
519_I522_K0.8320.65
252_A291_Y0.8300.65
518_K522_K0.8300.65
335_A458_I0.8290.64
341_Q386_R0.8280.64
530_Y534_A0.8270.64
227_Y232_L0.8270.64
245_I447_I0.8240.64
389_Q393_N0.8240.64
496_R499_K0.8230.64
205_I438_I0.8230.64
425_I429_E0.8220.64
301_F330_T0.8200.64
119_L210_F0.8200.64
48_V401_V0.8170.63
26_W30_R0.8170.63
512_S533_D0.8170.63
240_I267_V0.8150.63
455_Q496_R0.8140.63
222_I226_E0.8140.63
295_F413_L0.8130.63
179_I232_L0.8120.63
139_V208_K0.8120.63
105_L110_Q0.8110.63
215_S436_K0.8110.63
386_R389_Q0.8100.63
252_A417_I0.8100.63
221_A238_I0.8090.63
289_A335_A0.8090.63
501_K540_T0.8080.62
458_I465_K0.8080.62
400_V409_Y0.8070.62
258_F434_M0.8020.62
103_R154_S0.8020.62
182_S192_L0.7970.61
189_K532_I0.7970.61
105_L381_A0.7960.61
404_L409_Y0.7940.61
509_L537_A0.7920.61
366_V388_Q0.7900.61
311_I422_W0.7850.60
87_R114_S0.7840.60
150_D185_R0.7820.60
367_N371_E0.7810.60
278_D282_P0.7810.60
257_A421_A0.7770.59
318_A324_M0.7750.59
100_S107_E0.7740.59
357_V391_I0.7740.59
147_K503_E0.7730.59
151_I496_R0.7700.59
519_I552_W0.7690.59
374_A482_I0.7680.59
21_K24_S0.7680.59
63_G71_T0.7670.58
250_A289_A0.7630.58
486_N489_V0.7620.58
253_V417_I0.7610.58
488_E498_K0.7610.58
60_E63_G0.7600.58
243_Y331_Q0.7600.58
415_D423_K0.7590.58
525_E528_F0.7580.58
440_N443_P0.7560.57
39_T43_I0.7540.57
236_H283_H0.7510.57
423_K427_Q0.7510.57
52_L55_K0.7490.57
488_E491_E0.7490.57
87_R194_G0.7480.57
517_R555_Y0.7480.57
258_F424_I0.7450.56
403_P410_I0.7450.56
260_L425_I0.7420.56
102_F156_I0.7420.56
349_T367_N0.7420.56
455_Q459_E0.7410.56
66_G69_P0.7400.56
139_V209_N0.7320.55
146_W500_Y0.7310.55
492_R546_G0.7280.54
295_F407_S0.7270.54
286_F308_W0.7260.54
517_R525_E0.7250.54
494_I501_K0.7220.54
392_A398_A0.7210.54
257_A446_Q0.7210.54
291_Y297_E0.7200.54
93_G98_T0.7190.54
451_A455_Q0.7180.53
312_M324_M0.7180.53
20_E24_S0.7180.53
104_K108_A0.7180.53
246_R252_A0.7160.53
310_K418_E0.7150.53
60_E405_G0.7150.53
166_T202_K0.7140.53
281_A318_A0.7140.53
150_D180_A0.7120.53
33_R36_E0.7120.53
146_W184_S0.7120.53
170_T545_S0.7110.53
112_G195_T0.7100.53
472_Y476_W0.7100.53
341_Q382_K0.7100.53
397_A501_K0.7090.53
25_S28_K0.7090.53
334_G371_E0.7090.53
289_A300_K0.7070.52
239_S287_F0.7070.52
417_I421_A0.7060.52
32_E37_F0.7020.52
329_H365_H0.7000.52
100_S104_K0.6990.51
358_L397_A0.6970.51
230_K508_K0.6960.51
299_A413_L0.6950.51
498_K525_E0.6950.51
221_A225_I0.6940.51
25_S30_R0.6940.51
267_V308_W0.6930.51
507_M510_R0.6920.51
528_F531_M0.6920.51
101_R105_L0.6910.51
183_E187_I0.6910.51
23_Y26_W0.6910.51
515_N525_E0.6900.51
29_K32_E0.6890.50
314_E318_A0.6890.50
94_S97_E0.6880.50
343_E346_I0.6880.50
202_K244_H0.6880.50
290_A328_F0.6850.50
194_G233_P0.6840.50
68_Y313_K0.6840.50
225_I435_I0.6840.50
252_A354_L0.6840.50
212_Y548_L0.6830.50
68_Y324_M0.6830.50
335_A493_V0.6820.50
263_G286_F0.6820.50
497_L501_K0.6800.50
245_I434_M0.6800.50
50_T64_L0.6800.50
503_E517_R0.6790.49
221_A224_I0.6780.49
150_D177_M0.6770.49
338_T494_I0.6740.49
297_E352_Q0.6740.49
46_K412_W0.6740.49
94_S441_G0.6730.49
306_R310_K0.6730.49
65_P70_F0.6730.49
220_Y224_I0.6720.49
353_A366_V0.6720.49
360_G403_P0.6720.49
291_Y333_G0.6720.49
69_P73_G0.6690.48
70_F73_G0.6680.48
270_T273_R0.6660.48
267_V280_F0.6660.48
203_E207_R0.6650.48
225_I283_H0.6650.48
218_M221_A0.6650.48
253_V424_I0.6650.48
119_L207_R0.6640.48
260_L326_L0.6630.48
265_E434_M0.6620.48
258_F428_V0.6600.47
510_R539_A0.6570.47
125_L131_L0.6570.47
129_H133_Y0.6570.47
287_F331_Q0.6550.47
89_Y209_N0.6540.47
338_T344_I0.6540.47
89_Y114_S0.6500.46
196_V224_I0.6490.46
246_R255_E0.6480.46
445_A465_K0.6470.46
277_V323_S0.6460.46
501_K516_L0.6430.46
129_H549_R0.6430.46
90_A102_F0.6390.45
522_K551_I0.6380.45
341_Q473_E0.6370.45
488_E525_E0.6360.45
65_P294_I0.6360.45
89_Y119_L0.6330.45
264_M268_R0.6320.45
122_Q209_N0.6310.45
33_R37_F0.6310.45
246_R291_Y0.6290.44
310_K313_K0.6280.44
111_T160_K0.6270.44
422_W425_I0.6270.44
537_A541_V0.6260.44
240_I259_T0.6260.44
146_W177_M0.6250.44
41_S293_D0.6250.44
87_R285_S0.6240.44
227_Y231_Y0.6230.44
314_E317_N0.6230.44
183_E188_N0.6210.44
494_I500_Y0.6190.43
101_R381_A0.6190.43
271_M316_F0.6190.43
482_I485_V0.6180.43
241_S287_F0.6170.43
158_L185_R0.6170.43
233_P407_S0.6160.43
511_E517_R0.6150.43
350_T463_L0.6150.43
45_I400_V0.6140.43
176_S180_A0.6140.43
288_F326_L0.6140.43
473_E477_I0.6130.43
341_Q476_W0.6130.43
64_L76_P0.6130.43
343_E347_I0.6120.43
412_W415_D0.6120.43
256_V295_F0.6110.43
307_M311_I0.6110.43
369_Y399_D0.6110.43
190_S231_Y0.6070.42
320_K439_E0.6060.42
22_V27_V0.6060.42
41_S251_D0.6060.42
332_T364_L0.6060.42
47_P476_W0.6040.42
267_V277_V0.6040.42
21_K25_S0.6040.42
466_V472_Y0.6040.42
264_M317_N0.6040.42
106_L157_P0.6030.42
39_T252_A0.6030.42
390_I464_G0.6030.42
164_S194_G0.6020.42
519_I523_E0.6020.42
73_G405_G0.6000.41
500_Y503_E0.6000.41
511_E515_N0.6000.41
472_Y475_E0.5970.41
202_K205_I0.5960.41
298_V410_I0.5950.41
515_N518_K0.5920.41
114_S388_Q0.5920.41
241_S367_N0.5920.41
292_S390_I0.5910.41
49_Y295_F0.5900.40
279_E282_P0.5900.40
532_I536_R0.5900.40
236_H327_R0.5890.40
343_E383_I0.5890.40
88_Q110_Q0.5880.40
243_Y247_E0.5870.40
522_K536_R0.5860.40
431_M440_N0.5860.40
83_I86_I0.5850.40
279_E323_S0.5850.40
382_K476_W0.5840.40
150_D181_T0.5840.40
42_G494_I0.5830.40
95_A152_V0.5830.40
173_E544_T0.5820.40
502_Q507_M0.5820.40
178_L235_W0.5810.40
99_N152_V0.5800.39
512_S524_N0.5800.39
200_I212_Y0.5800.39
504_R507_M0.5780.39
223_D227_Y0.5780.39
264_M318_A0.5780.39
64_L401_V0.5760.39
285_S329_H0.5760.39
129_H542_G0.5760.39
329_H384_A0.5740.39
350_T390_I0.5730.39
488_E495_S0.5730.39
407_S410_I0.5730.39
453_K456_K0.5730.39
271_M276_N0.5720.39
532_I535_I0.5720.39
500_Y509_L0.5710.39
357_V392_A0.5700.38
319_K324_M0.5700.38
487_P492_R0.5700.38
461_G472_Y0.5700.38
105_L385_I0.5690.38
254_L443_P0.5690.38
351_L354_L0.5680.38
113_L166_T0.5660.38
501_K542_G0.5660.38
417_I424_I0.5650.38
271_M318_A0.5650.38
360_G405_G0.5650.38
149_M178_L0.5650.38
340_Q468_V0.5640.38
74_I405_G0.5640.38
311_I555_Y0.5630.38
20_E23_Y0.5630.38
39_T296_E0.5620.38
525_E550_D0.5610.38
511_E537_A0.5610.38
267_V316_F0.5600.37
431_M446_Q0.5590.37
514_N525_E0.5590.37
304_A328_F0.5590.37
337_L376_P0.5570.37
525_E529_P0.5570.37
70_F477_I0.5560.37
511_E514_N0.5560.37
331_Q365_H0.5540.37
22_V32_E0.5540.37
320_K324_M0.5530.37
98_T115_M0.5520.37
179_I465_K0.5520.37
225_I280_F0.5510.37
147_K555_Y0.5500.37
260_L264_M0.5500.37
116_A166_T0.5490.36
450_S454_I0.5480.36
400_V403_P0.5480.36
368_S548_L0.5470.36
527_L548_L0.5470.36
41_S341_Q0.5460.36
101_R104_K0.5460.36
436_K498_K0.5450.36
290_A355_A0.5430.36
292_S395_S0.5420.36
409_Y413_L0.5420.36
153_M175_L0.5420.36
245_I259_T0.5420.36
382_K501_K0.5390.35
215_S218_M0.5390.35
517_R533_D0.5390.35
61_K64_L0.5380.35
121_T174_L0.5380.35
258_F446_Q0.5370.35
75_Y460_E0.5370.35
34_K56_G0.5370.35
480_T488_E0.5360.35
275_I279_E0.5360.35
167_I171_A0.5350.35
159_D188_N0.5340.35
498_K517_R0.5340.35
87_R195_T0.5330.35
123_L554_E0.5320.35
256_V307_M0.5320.35
147_K499_K0.5320.35
502_Q514_N0.5310.35
28_K35_K0.5290.35
85_T195_T0.5290.35
508_K511_E0.5280.34
242_G245_I0.5270.34
492_R532_I0.5270.34
114_S365_H0.5270.34
425_I541_V0.5260.34
189_K536_R0.5260.34
476_W479_T0.5260.34
337_L352_Q0.5250.34
96_E130_E0.5250.34
144_F493_V0.5250.34
75_Y377_T0.5250.34
291_Y352_Q0.5240.34
493_V496_R0.5240.34
212_Y417_I0.5240.34
22_V25_S0.5230.34
525_E537_A0.5220.34
243_Y334_G0.5210.34
60_E415_D0.5210.34
322_E325_M0.5210.34
383_I552_W0.5210.34
317_N320_K0.5210.34
267_V271_M0.5210.34
103_R157_P0.5210.34
338_T465_K0.5210.34
155_G317_N0.5210.34
498_K550_D0.5200.34
282_P311_I0.5190.34
110_Q405_G0.5190.34
56_G412_W0.5190.34
43_I296_E0.5190.34
544_T550_D0.5180.34
454_I458_I0.5180.34
86_I392_A0.5180.34
239_S285_S0.5170.33
242_G262_D0.5160.33
547_V550_D0.5160.33
337_L349_T0.5150.33
418_E422_W0.5150.33
363_S384_A0.5140.33
277_V316_F0.5140.33
510_R515_N0.5140.33
41_S386_R0.5140.33
152_V251_D0.5130.33
512_S534_A0.5130.33
39_T42_G0.5130.33
252_A255_E0.5130.33
219_R273_R0.5130.33
204_Y439_E0.5130.33
35_K64_L0.5120.33
26_W34_K0.5120.33
26_W29_K0.5120.33
498_K546_G0.5110.33
491_E499_K0.5110.33
71_T414_T0.5110.33
122_Q135_E0.5110.33
40_F450_S0.5100.33
250_A369_Y0.5100.33
197_Q287_F0.5090.33
74_I325_M0.5090.33
46_K541_V0.5090.33
205_I245_I0.5080.33
219_R278_D0.5070.33
419_E550_D0.5070.33
226_E269_K0.5070.33
259_T326_L0.5070.33
492_R497_L0.5050.32
294_I352_Q0.5050.32
78_M401_V0.5050.32
77_N81_G0.5050.32
391_I476_W0.5050.32
324_M551_I0.5040.32
272_E430_K0.5040.32
297_E300_K0.5040.32
165_M174_L0.5030.32
93_G318_A0.5010.32
389_Q392_A0.5010.32
517_R528_F0.5010.32
170_T212_Y0.5010.32
296_E341_Q0.5000.32
215_S273_R0.5000.32
517_R532_I0.5000.32
466_V470_M0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4r3uA 2 0.9911 100 0.069 Contact Map
2xijA 2 0.9733 100 0.089 Contact Map
1reqA 1 0.9857 100 0.098 Contact Map
4xc8A 2 0.975 100 0.153 Contact Map
1reqB 1 0.9216 100 0.216 Contact Map
3kp1A 2 0.8895 100 0.475 Contact Map
1ccwB 2 0.7861 100 0.803 Contact Map
3oa3A 2 0.3939 67 0.978 Contact Map
2yciX 2 0.4724 45.1 0.981 Contact Map
3bijA 5 0.1355 29.3 0.983 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0149 seconds.