Q97VY8 - SULSO - GREMLIN Contacts

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Q97VY8 - Propionyl-CoA carboxylase beta subunit (PpcB)

UniProt:	Q97VY8	Sequences: MALYEKPSMDKLIEDLKILKEKVYKGGGEEKINFQHGKGKLTARERLNQLFDEGKFNEILTFATTRATEFGLDKNRFYGDGVIAGWGKIDGRQVFAYAQDFTILGGSLGETHANKIVRAYELALKVGAPVIGINDSGGARIQEGALSLEGYGAVFKMNVMASGVIPQITIMAGPAAGGAVYSPALTDFLIMIKGDAYYMFVTGPEITKVSIGEEVSYQDLGGAIIHATKSGVVHFVAENEQDAINITKRLLSYLPSNNMEEPPYVDTGDPADRAVQSAESIVPTDSVKPFDIRDLIYNIVDNSEFLEVHKLWAQNITVGFGRINGNVVGIVANNSAYYGGAIDIDAADKAARFIRFCDAFNIPVISLVDTPGYVPGTDQEYKGIIRHGAKMLYAFAEATVPKITVIVRRSYGGAHIAMSIKSLGADLVYAWPSAEIAVTGPEGAVRILYRREIQSAQNPEELLKQKITEYKKLFANPYWAAEKGLIDDVIEPKDTRNVIARGLEMLRNKREFRYPKKHGNIPL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	523 (490)
Sequences:	5252 (2317)
Seq/√Len:	104.7

BACSU - PCCB YNGE
HALSA - Q9HRN1 Q9HPQ0
SULSO - Q97VY8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
300_V	321_G	4.953	1.00
292_I	317_T	4.785	1.00
305_F	319_G	4.610	1.00
193_K	238_E	4.371	1.00
216_S	219_D	4.366	1.00
316_I	350_A	4.348	1.00
51_F	87_G	4.181	1.00
29_E	33_N	3.994	1.00
51_F	96_A	3.820	1.00
170_I	247_T	3.688	1.00
299_I	367_L	3.558	1.00
208_K	214_E	3.400	1.00
55_K	88_K	3.256	1.00
365_I	503_L	3.042	1.00
323_I	499_I	3.040	1.00
329_G	357_C	2.951	1.00
121_E	157_M	2.944	1.00
279_E	493_K	2.861	1.00
368_V	404_T	2.751	1.00
33_N	37_G	2.698	1.00
405_V	495_T	2.691	1.00
292_I	407_V	2.683	1.00
56_F	85_G	2.623	1.00
190_I	247_T	2.614	1.00
465_Q	469_E	2.444	1.00
279_E	491_E	2.412	1.00
235_F	308_V	2.406	1.00
239_N	242_D	2.385	1.00
321_G	330_I	2.318	1.00
95_F	119_A	2.312	1.00
169_T	186_T	2.293	1.00
348_D	387_H	2.279	1.00
237_A	246_I	2.234	1.00
300_V	330_I	2.212	1.00
227_A	311_L	2.208	1.00
324_N	500_A	2.166	1.00
328_V	365_I	2.156	1.00
431_W	495_T	2.154	1.00
223_A	236_V	2.111	1.00
43_A	83_I	2.103	1.00
15_D	19_L	2.095	1.00
95_F	128_A	2.079	1.00
190_I	243_A	2.077	1.00
275_V	298_N	2.075	1.00
36_H	45_E	2.070	1.00
238_E	242_D	2.059	1.00
494_D	497_N	2.032	1.00
227_A	233_V	2.019	1.00
403_I	503_L	2.011	1.00
32_I	36_H	2.009	1.00
41_L	49_Q	1.995	1.00
365_I	499_I	1.978	1.00
215_V	377_T	1.957	1.00
193_K	224_I	1.932	1.00
295_L	407_V	1.923	1.00
326_N	507_R	1.873	1.00
60_L	118_R	1.872	1.00
227_A	236_V	1.865	1.00
324_N	504_E	1.864	1.00
367_L	405_V	1.861	1.00
14_E	18_I	1.830	1.00
323_I	500_A	1.822	1.00
191_M	196_A	1.816	1.00
49_Q	241_Q	1.815	1.00
47_L	51_F	1.807	1.00
358_D	399_T	1.787	1.00
296_I	300_V	1.775	1.00
253_Y	304_E	1.772	1.00
458_N	461_E	1.766	1.00
242_D	246_I	1.748	1.00
225_I	381_Y	1.738	1.00
90_D	252_S	1.735	1.00
93_Q	128_A	1.726	1.00
190_I	246_I	1.723	1.00
350_A	391_M	1.717	1.00
82_V	116_I	1.711	1.00
47_L	96_A	1.706	1.00
430_A	434_A	1.697	1.00
43_A	98_A	1.689	1.00
20_K	61_T	1.680	1.00
20_K	488_D	1.653	1.00
92_R	255_P	1.647	1.00
224_I	228_T	1.636	1.00
469_E	473_L	1.611	1.00
234_H	309_H	1.607	1.00
17_K	491_E	1.601	1.00
97_Y	132_G	1.601	1.00
25_K	29_E	1.593	1.00
120_Y	130_V	1.582	1.00
133_I	170_I	1.573	1.00
64_T	80_D	1.568	1.00
190_I	237_A	1.563	1.00
124_L	161_A	1.561	1.00
229_K	381_Y	1.554	1.00
277_S	298_N	1.547	1.00
193_K	236_V	1.545	1.00
293_R	307_E	1.539	1.00
49_Q	245_N	1.530	1.00
190_I	250_L	1.529	1.00
456_A	462_L	1.528	1.00
403_I	499_I	1.519	1.00
51_F	55_K	1.502	1.00
172_A	240_E	1.497	1.00
15_D	18_I	1.489	1.00
488_D	498_V	1.481	1.00
377_T	381_Y	1.479	1.00
50_L	89_I	1.475	1.00
354_I	398_A	1.467	1.00
49_Q	244_I	1.465	1.00
365_I	403_I	1.453	1.00
427_L	502_G	1.440	1.00
463_L	466_K	1.428	1.00
464_K	468_T	1.426	1.00
296_I	367_L	1.425	1.00
66_R	110_E	1.424	1.00
441_P	471_K	1.410	1.00
405_V	499_I	1.400	1.00
268_G	304_E	1.393	1.00
88_K	93_Q	1.392	1.00
429_Y	498_V	1.386	1.00
462_L	465_Q	1.381	1.00
456_A	461_E	1.378	1.00
468_T	472_K	1.377	1.00
355_R	397_E	1.374	1.00
34_F	37_G	1.367	1.00
330_I	365_I	1.354	0.99
63_A	111_T	1.354	0.99
453_I	456_A	1.352	0.99
312_W	345_D	1.348	0.99
124_L	163_G	1.343	0.99
172_A	244_I	1.338	0.99
21_E	24_Y	1.337	0.99
24_Y	61_T	1.328	0.99
296_I	330_I	1.323	0.99
456_A	460_E	1.318	0.99
80_D	111_T	1.318	0.99
32_I	42_T	1.313	0.99
120_Y	157_M	1.304	0.99
84_A	119_A	1.295	0.99
16_L	478_Y	1.286	0.99
19_L	22_K	1.282	0.99
403_I	506_L	1.281	0.99
300_V	323_I	1.278	0.99
463_L	467_I	1.276	0.99
358_D	398_A	1.272	0.99
249_R	304_E	1.266	0.99
296_I	319_G	1.265	0.99
237_A	242_D	1.259	0.99
146_L	483_K	1.259	0.99
61_T	488_D	1.259	0.99
133_I	172_A	1.258	0.99
23_V	62_F	1.255	0.99
327_V	362_I	1.252	0.99
243_A	247_T	1.247	0.99
107_S	137_G	1.246	0.99
237_A	243_A	1.246	0.99
491_E	494_D	1.244	0.99
246_I	249_R	1.244	0.99
200_F	217_Y	1.244	0.99
17_K	20_K	1.241	0.99
456_A	459_P	1.237	0.99
291_D	294_D	1.232	0.99
133_I	244_I	1.231	0.99
293_R	317_T	1.229	0.99
15_D	476_N	1.229	0.99
28_G	32_I	1.227	0.99
25_K	32_I	1.225	0.99
309_H	318_V	1.222	0.99
92_R	256_S	1.221	0.99
19_L	478_Y	1.219	0.99
30_E	33_N	1.218	0.99
344_I	382_K	1.205	0.99
492_P	495_T	1.201	0.99
219_D	377_T	1.193	0.99
235_F	246_I	1.181	0.99
410_S	415_H	1.180	0.99
403_I	502_G	1.176	0.99
411_Y	435_E	1.154	0.98
20_K	24_Y	1.148	0.98
470_Y	474_F	1.144	0.98
276_Q	279_E	1.143	0.98
86_W	95_F	1.142	0.98
113_A	150_G	1.140	0.98
95_F	126_V	1.136	0.98
458_N	462_L	1.136	0.98
242_D	245_N	1.136	0.98
41_L	240_E	1.131	0.98
452_E	456_A	1.129	0.98
366_S	395_F	1.128	0.98
277_S	280_S	1.126	0.98
291_D	334_N	1.122	0.98
158_N	182_S	1.117	0.98
188_F	235_F	1.116	0.98
29_E	32_I	1.113	0.98
445_V	467_I	1.108	0.98
161_A	165_I	1.106	0.98
354_I	364_V	1.105	0.98
170_I	190_I	1.105	0.98
88_K	504_E	1.105	0.98
373_Y	417_A	1.101	0.98
436_I	480_A	1.097	0.98
440_G	443_G	1.093	0.98
153_A	422_S	1.092	0.98
42_T	45_E	1.091	0.98
235_F	310_K	1.087	0.98
90_D	256_S	1.087	0.98
276_Q	493_K	1.085	0.98
23_V	79_G	1.077	0.97
452_E	455_S	1.076	0.97
228_T	311_L	1.073	0.97
429_Y	502_G	1.069	0.97
149_E	422_S	1.066	0.97
168_I	247_T	1.065	0.97
172_A	195_D	1.065	0.97
36_H	42_T	1.063	0.97
152_G	416_I	1.063	0.97
80_D	140_R	1.063	0.97
27_G	102_T	1.062	0.97
246_I	306_L	1.062	0.97
328_V	503_L	1.062	0.97
18_I	22_K	1.060	0.97
20_K	494_D	1.059	0.97
296_I	305_F	1.055	0.97
47_L	98_A	1.043	0.97
205_E	450_R	1.037	0.97
18_I	21_E	1.031	0.97
44_R	58_E	1.025	0.97
67_A	111_T	1.017	0.96
25_K	28_G	1.010	0.96
101_F	174_P	1.009	0.96
77_F	104_L	1.007	0.96
125_K	426_D	1.002	0.96
333_N	418_M	1.001	0.96
158_N	167_Q	0.995	0.96
365_I	405_V	0.994	0.96
114_N	153_A	0.991	0.96
86_W	93_Q	0.990	0.96
267_T	324_N	0.986	0.96
35_Q	101_F	0.985	0.96
122_L	126_V	0.984	0.96
45_E	48_N	0.982	0.96
35_Q	40_K	0.980	0.96
87_G	96_A	0.974	0.95
249_R	306_L	0.973	0.95
213_E	377_T	0.973	0.95
321_G	328_V	0.971	0.95
294_D	297_Y	0.970	0.95
429_Y	488_D	0.968	0.95
268_G	271_A	0.967	0.95
93_Q	505_M	0.967	0.95
259_M	510_R	0.965	0.95
117_V	157_M	0.963	0.95
126_V	426_D	0.959	0.95
64_T	111_T	0.957	0.95
378_D	382_K	0.956	0.95
116_I	154_V	0.954	0.95
64_T	76_R	0.953	0.95
453_I	459_P	0.953	0.95
57_N	501_R	0.952	0.95
34_F	38_K	0.949	0.95
457_Q	462_L	0.943	0.94
446_R	463_L	0.942	0.94
172_A	192_I	0.936	0.94
93_Q	504_E	0.929	0.94
235_F	306_L	0.926	0.94
188_F	250_L	0.926	0.94
307_E	310_K	0.925	0.94
300_V	365_I	0.925	0.94
109_G	140_R	0.920	0.94
351_A	394_A	0.920	0.94
124_L	165_I	0.916	0.94
59_I	122_L	0.915	0.94
127_G	163_G	0.913	0.93
144_G	148_L	0.913	0.93
264_Y	326_N	0.912	0.93
60_L	84_A	0.912	0.93
409_R	435_E	0.912	0.93
421_K	487_D	0.912	0.93
395_F	419_S	0.910	0.93
86_W	128_A	0.907	0.93
430_A	480_A	0.904	0.93
457_Q	460_E	0.904	0.93
240_E	244_I	0.904	0.93
326_N	504_E	0.901	0.93
350_A	354_I	0.900	0.93
86_W	126_V	0.894	0.93
402_K	419_S	0.893	0.93
323_I	405_V	0.893	0.93
367_L	407_V	0.892	0.93
236_V	311_L	0.889	0.93
28_G	31_K	0.888	0.93
181_Y	388_G	0.888	0.93
265_V	322_R	0.887	0.92
57_N	86_W	0.887	0.92
224_I	311_L	0.885	0.92
316_I	342_I	0.880	0.92
269_D	274_A	0.880	0.92
89_I	94_V	0.877	0.92
344_I	387_H	0.877	0.92
124_L	160_M	0.877	0.92
215_V	219_D	0.876	0.92
449_Y	464_K	0.876	0.92
314_Q	337_Y	0.872	0.92
356_F	360_F	0.870	0.92
268_G	302_N	0.870	0.92
136_S	179_A	0.867	0.92
271_A	302_N	0.867	0.92
121_E	125_K	0.864	0.91
294_D	298_N	0.863	0.91
416_I	422_S	0.863	0.91
453_I	457_Q	0.863	0.91
364_V	419_S	0.857	0.91
331_V	354_I	0.857	0.91
364_V	402_K	0.857	0.91
20_K	62_F	0.857	0.91
450_R	454_Q	0.856	0.91
308_V	318_V	0.853	0.91
378_D	381_Y	0.853	0.91
190_I	235_F	0.852	0.91
404_T	428_V	0.851	0.91
461_E	465_Q	0.846	0.91
180_V	385_I	0.845	0.91
24_Y	48_N	0.840	0.90
59_I	119_A	0.840	0.90
21_E	25_K	0.839	0.90
293_R	334_N	0.838	0.90
64_T	482_E	0.834	0.90
445_V	453_I	0.832	0.90
159_V	185_L	0.832	0.90
47_L	83_I	0.828	0.90
92_R	263_P	0.827	0.90
244_I	248_K	0.825	0.89
99_Q	112_H	0.825	0.89
93_Q	126_V	0.824	0.89
256_S	260_E	0.822	0.89
224_I	236_V	0.822	0.89
456_A	463_L	0.822	0.89
442_E	467_I	0.819	0.89
14_E	17_K	0.817	0.89
321_G	365_I	0.816	0.89
59_I	84_A	0.812	0.89
105_G	137_G	0.811	0.89
243_A	246_I	0.810	0.89
22_K	76_R	0.810	0.89
462_L	466_K	0.808	0.88
490_I	495_T	0.806	0.88
297_Y	304_E	0.803	0.88
281_I	298_N	0.802	0.88
159_V	396_A	0.801	0.88
153_A	424_G	0.801	0.88
425_A	428_V	0.800	0.88
429_Y	490_I	0.799	0.88
188_F	356_F	0.799	0.88
131_I	168_I	0.795	0.88
269_D	272_D	0.795	0.88
170_I	244_I	0.794	0.88
117_V	121_E	0.794	0.88
253_Y	327_V	0.794	0.88
108_L	116_I	0.793	0.88
241_Q	245_N	0.792	0.87
382_K	387_H	0.792	0.87
267_T	271_A	0.790	0.87
406_I	428_V	0.789	0.87
131_I	251_L	0.789	0.87
170_I	243_A	0.787	0.87
323_I	328_V	0.786	0.87
215_V	381_Y	0.781	0.87
17_K	21_E	0.780	0.87
109_G	112_H	0.780	0.87
441_P	475_A	0.779	0.87
261_E	326_N	0.778	0.87
494_D	498_V	0.775	0.86
78_Y	103_I	0.774	0.86
468_T	471_K	0.773	0.86
143_E	474_F	0.772	0.86
442_E	446_R	0.772	0.86
190_I	306_L	0.771	0.86
156_K	396_A	0.768	0.86
94_V	131_I	0.767	0.86
142_Q	178_G	0.767	0.86
406_I	430_A	0.766	0.86
110_E	483_K	0.766	0.86
427_L	505_M	0.766	0.86
226_H	230_S	0.765	0.86
155_F	159_V	0.764	0.86
459_P	462_L	0.762	0.85
48_N	53_E	0.762	0.85
406_I	434_A	0.761	0.85
318_V	353_F	0.761	0.85
51_F	94_V	0.759	0.85
35_Q	42_T	0.758	0.85
285_D	288_K	0.757	0.85
81_G	112_H	0.755	0.85
97_Y	130_V	0.753	0.85
95_F	122_L	0.752	0.85
32_I	35_Q	0.750	0.85
355_R	394_A	0.750	0.85
442_E	471_K	0.750	0.85
149_E	153_A	0.749	0.84
50_L	131_I	0.749	0.84
431_W	492_P	0.748	0.84
110_E	146_L	0.747	0.84
417_A	428_V	0.746	0.84
396_A	423_L	0.745	0.84
451_R	455_S	0.743	0.84
41_L	241_Q	0.743	0.84
127_G	257_N	0.742	0.84
164_V	258_N	0.741	0.84
315_N	343_D	0.740	0.84
366_S	402_K	0.738	0.84
63_A	484_G	0.738	0.84
324_N	497_N	0.737	0.83
199_M	385_I	0.736	0.83
311_L	314_Q	0.734	0.83
90_D	248_K	0.734	0.83
111_T	114_N	0.732	0.83
25_K	33_N	0.731	0.83
348_D	386_R	0.730	0.83
142_Q	146_L	0.729	0.83
112_H	116_I	0.729	0.83
471_K	475_A	0.726	0.83
499_I	502_G	0.726	0.83
320_F	356_F	0.725	0.82
498_V	501_R	0.723	0.82
261_E	510_R	0.723	0.82
64_T	67_A	0.721	0.82
137_G	447_I	0.719	0.82
504_E	507_R	0.717	0.82
209_V	446_R	0.716	0.82
388_G	438_V	0.716	0.82
35_Q	38_K	0.713	0.81
16_L	20_K	0.712	0.81
122_L	125_K	0.711	0.81
281_I	295_L	0.711	0.81
364_V	398_A	0.711	0.81
162_S	359_A	0.710	0.81
30_E	34_F	0.709	0.81
155_F	178_G	0.709	0.81
449_Y	452_E	0.707	0.81
255_P	258_N	0.707	0.81
251_L	327_V	0.705	0.81
20_K	23_V	0.702	0.80
55_K	85_G	0.701	0.80
497_N	501_R	0.700	0.80
168_I	250_L	0.700	0.80
15_D	478_Y	0.699	0.80
481_A	486_I	0.699	0.80
453_I	462_L	0.699	0.80
93_Q	508_N	0.699	0.80
247_T	250_L	0.698	0.80
479_W	482_E	0.698	0.80
430_A	486_I	0.698	0.80
14_E	19_L	0.694	0.80
297_Y	303_S	0.693	0.80
380_E	383_G	0.692	0.79
51_F	89_I	0.692	0.79
264_Y	324_N	0.690	0.79
191_M	233_V	0.688	0.79
269_D	275_V	0.688	0.79
388_G	440_G	0.687	0.79
354_I	395_F	0.686	0.79
421_K	428_V	0.685	0.79
282_V	286_S	0.684	0.79
477_P	480_A	0.684	0.79
451_R	460_E	0.681	0.78
35_Q	102_T	0.677	0.78
121_E	424_G	0.677	0.78
192_I	239_N	0.677	0.78
131_I	247_T	0.675	0.78
305_F	317_T	0.675	0.78
225_I	229_K	0.673	0.78
58_E	115_K	0.673	0.78
432_P	492_P	0.672	0.77
185_L	393_Y	0.671	0.77
117_V	153_A	0.671	0.77
466_K	469_E	0.671	0.77
145_A	148_L	0.670	0.77
370_T	384_I	0.668	0.77
36_H	43_A	0.668	0.77
69_E	473_L	0.664	0.77
142_Q	148_L	0.664	0.77
368_V	419_S	0.663	0.76
455_S	458_N	0.661	0.76
33_N	36_H	0.661	0.76
130_V	165_I	0.660	0.76
457_Q	461_E	0.660	0.76
195_D	244_I	0.660	0.76
246_I	250_L	0.658	0.76
431_W	490_I	0.658	0.76
342_I	347_A	0.657	0.76
274_A	494_D	0.656	0.76
364_V	395_F	0.656	0.76
253_Y	306_L	0.656	0.76
257_N	361_N	0.655	0.76
406_I	436_I	0.654	0.76
95_F	505_M	0.654	0.76
152_G	422_S	0.653	0.75
275_V	497_N	0.651	0.75
83_I	98_A	0.648	0.75
178_G	203_G	0.647	0.75
27_G	32_I	0.647	0.75
181_Y	438_V	0.647	0.75
27_G	31_K	0.646	0.75
23_V	481_A	0.646	0.75
316_I	331_V	0.646	0.75
467_I	470_Y	0.645	0.75
271_A	324_N	0.644	0.74
272_D	297_Y	0.644	0.74
154_V	159_V	0.643	0.74
495_T	499_I	0.642	0.74
312_W	348_D	0.642	0.74
96_A	131_I	0.640	0.74
139_A	438_V	0.640	0.74
428_V	486_I	0.640	0.74
40_K	195_D	0.639	0.74
86_W	505_M	0.639	0.74
498_V	502_G	0.639	0.74
315_N	346_A	0.638	0.74
153_A	157_M	0.638	0.74
89_I	244_I	0.637	0.74
252_S	322_R	0.636	0.73
137_G	203_G	0.636	0.73
52_D	55_K	0.636	0.73
21_E	37_G	0.635	0.73
437_A	475_A	0.632	0.73
89_I	251_L	0.632	0.73
352_R	386_R	0.632	0.73
271_A	275_V	0.632	0.73
365_I	506_L	0.630	0.73
422_S	485_L	0.630	0.73
156_K	424_G	0.626	0.72
60_L	63_A	0.624	0.72
22_K	25_K	0.623	0.72
19_L	476_N	0.623	0.72
117_V	120_Y	0.620	0.72
277_S	295_L	0.619	0.71
47_L	55_K	0.617	0.71
387_H	390_K	0.615	0.71
274_A	277_S	0.613	0.71
455_S	460_E	0.613	0.71
264_Y	327_V	0.612	0.71
435_E	471_K	0.611	0.71
445_V	466_K	0.611	0.71
105_G	133_I	0.610	0.70
169_T	183_P	0.609	0.70
323_I	403_I	0.609	0.70
272_D	277_S	0.607	0.70
53_E	267_T	0.607	0.70
192_I	243_A	0.606	0.70
81_G	100_D	0.605	0.70
43_A	47_L	0.604	0.70
465_Q	468_T	0.603	0.70
269_D	497_N	0.603	0.70
384_I	388_G	0.603	0.70
87_G	223_A	0.602	0.69
467_I	471_K	0.602	0.69
404_T	419_S	0.601	0.69
351_A	354_I	0.600	0.69
274_A	299_I	0.600	0.69
107_S	140_R	0.600	0.69
84_A	95_F	0.600	0.69
40_K	101_F	0.599	0.69
51_F	88_K	0.598	0.69
156_K	160_M	0.598	0.69
479_W	483_K	0.598	0.69
249_R	252_S	0.598	0.69
146_L	485_L	0.597	0.69
135_D	175_A	0.596	0.69
502_G	506_L	0.595	0.68
503_L	506_L	0.594	0.68
506_L	509_K	0.594	0.68
82_V	112_H	0.591	0.68
419_S	425_A	0.591	0.68
262_P	327_V	0.591	0.68
371_P	409_R	0.591	0.68
466_K	470_Y	0.590	0.68
286_S	435_E	0.590	0.68
274_A	493_K	0.589	0.68
348_D	390_K	0.587	0.67
455_S	459_P	0.587	0.67
281_I	294_D	0.587	0.67
16_L	21_E	0.586	0.67
171_M	183_P	0.585	0.67
505_M	509_K	0.585	0.67
453_I	458_N	0.584	0.67
230_S	383_G	0.584	0.67
105_G	447_I	0.583	0.67
444_A	471_K	0.582	0.67
146_L	149_E	0.582	0.67
19_L	23_V	0.580	0.67
265_V	268_G	0.579	0.66
442_E	464_K	0.579	0.66
322_R	327_V	0.578	0.66
435_E	475_A	0.578	0.66
224_I	238_E	0.577	0.66
451_R	458_N	0.577	0.66
439_T	444_A	0.576	0.66
256_S	263_P	0.576	0.66
307_E	349_K	0.576	0.66
341_A	346_A	0.576	0.66
469_E	472_K	0.574	0.66
331_V	358_D	0.573	0.66
403_I	429_Y	0.573	0.66
50_L	96_A	0.573	0.66
55_K	131_I	0.572	0.65
282_V	295_L	0.572	0.65
148_L	151_Y	0.572	0.65
120_Y	167_Q	0.572	0.65
14_E	29_E	0.571	0.65
143_E	470_Y	0.571	0.65
92_R	127_G	0.571	0.65
305_F	318_V	0.570	0.65
114_N	118_R	0.570	0.65
185_L	423_L	0.569	0.65
80_D	104_L	0.569	0.65
354_I	394_A	0.568	0.65
135_D	179_A	0.568	0.65
48_N	54_G	0.566	0.65
121_E	148_L	0.565	0.65
452_E	466_K	0.564	0.64
342_I	346_A	0.564	0.64
59_I	95_F	0.564	0.64
263_P	322_R	0.563	0.64
123_A	165_I	0.563	0.64
81_G	140_R	0.562	0.64
391_M	418_M	0.561	0.64
23_V	61_T	0.560	0.64
496_R	499_I	0.560	0.64
67_A	75_N	0.560	0.64
195_D	240_E	0.559	0.64
474_F	479_W	0.559	0.64
505_M	508_N	0.558	0.64
153_A	485_L	0.557	0.63
290_F	408_R	0.557	0.63
305_F	367_L	0.556	0.63
194_G	218_Q	0.556	0.63
295_L	298_N	0.555	0.63
366_S	419_S	0.555	0.63
250_L	306_L	0.555	0.63
251_L	254_L	0.555	0.63
424_G	480_A	0.554	0.63
269_D	324_N	0.554	0.63
26_G	31_K	0.553	0.63
345_D	382_K	0.553	0.63
261_E	507_R	0.552	0.63
370_T	414_A	0.551	0.63
120_Y	132_G	0.550	0.62
234_H	308_V	0.550	0.62
259_M	361_N	0.549	0.62
370_T	373_Y	0.548	0.62
348_D	417_A	0.548	0.62
51_F	131_I	0.546	0.62
108_L	151_Y	0.545	0.62
293_R	310_K	0.545	0.62
207_T	446_R	0.545	0.62
29_E	37_G	0.544	0.62
356_F	362_I	0.544	0.62
207_T	220_L	0.543	0.61
127_G	164_V	0.543	0.61
364_V	400_V	0.543	0.61
174_P	198_Y	0.543	0.61
375_P	413_G	0.541	0.61
199_M	232_V	0.540	0.61
181_Y	203_G	0.540	0.61
23_V	28_G	0.539	0.61
262_P	361_N	0.536	0.60
176_A	200_F	0.536	0.60
99_Q	120_Y	0.536	0.60
450_R	455_S	0.536	0.60
292_I	332_A	0.535	0.60
152_G	420_I	0.534	0.60
281_I	336_A	0.534	0.60
442_E	468_T	0.534	0.60
120_Y	161_A	0.534	0.60
101_F	105_G	0.533	0.60
272_D	497_N	0.533	0.60
92_R	251_L	0.531	0.60
178_G	181_Y	0.530	0.60
266_D	270_P	0.529	0.60
507_R	510_R	0.529	0.60
245_N	248_K	0.529	0.60
30_E	37_G	0.529	0.60
351_A	391_M	0.529	0.60
26_G	103_I	0.528	0.59
17_K	23_V	0.527	0.59
200_F	205_E	0.527	0.59
296_I	317_T	0.525	0.59
178_G	439_T	0.524	0.59
262_P	326_N	0.524	0.59
127_G	509_K	0.523	0.59
120_Y	158_N	0.522	0.58
159_V	370_T	0.521	0.58
134_N	179_A	0.521	0.58
341_A	374_V	0.520	0.58
501_R	505_M	0.519	0.58
162_S	390_K	0.519	0.58
329_G	353_F	0.518	0.58
139_A	145_A	0.517	0.58
118_R	122_L	0.517	0.58
177_G	206_I	0.517	0.58
94_V	255_P	0.516	0.58
359_A	390_K	0.516	0.58
343_D	346_A	0.516	0.58
55_K	94_V	0.515	0.57
413_G	416_I	0.514	0.57
426_D	509_K	0.512	0.57
18_I	29_E	0.512	0.57
156_K	159_V	0.511	0.57
272_D	303_S	0.510	0.57
32_I	102_T	0.509	0.57
69_E	75_N	0.509	0.57
155_F	183_P	0.509	0.57
135_D	172_A	0.508	0.56
278_A	282_V	0.508	0.56
90_D	94_V	0.508	0.56
278_A	295_L	0.507	0.56
31_K	34_F	0.507	0.56
203_G	413_G	0.506	0.56
453_I	466_K	0.505	0.56
210_S	213_E	0.505	0.56
419_S	424_G	0.504	0.56
267_T	322_R	0.504	0.56
257_N	260_E	0.503	0.56
451_R	454_Q	0.503	0.56
267_T	270_P	0.503	0.56
224_I	227_A	0.502	0.56
368_V	416_I	0.502	0.56
181_Y	413_G	0.502	0.56
128_A	505_M	0.502	0.56
225_I	228_T	0.502	0.56
351_A	355_R	0.501	0.55
419_S	423_L	0.501	0.55
62_F	481_A	0.501	0.55
298_N	303_S	0.500	0.55
264_Y	504_E	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vrgA	4	0.9828	100	0.121	Contact Map
3n6rB	4	0.9675	100	0.122	Contact Map
3u9rB	5	0.9732	100	0.159	Contact Map
2bzrA	4	0.9656	100	0.16	Contact Map
3iavA	4	0.9904	100	0.171	Contact Map
4rcnA	6	0.912	100	0.176	Contact Map
1pixA	4	0.9751	100	0.18	Contact Map
3gf3A	4	0.9637	100	0.182	Contact Map
1on3A	6	0.9847	100	0.185	Contact Map
1x0uA	5	0.9885	100	0.192	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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