GREMLIN Database
Q97VY0 - Glucan 1,4 alpha glucosidase (Glucoamylase)
UniProt: Q97VY0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 612 (570)
Sequences: 640 (510)
Seq/√Len: 21.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
433_R445_E6.6291.00
386_A428_A5.9941.00
409_E522_Y5.6091.00
255_L302_M5.1331.00
254_S594_H4.8841.00
426_R445_E4.3961.00
300_E364_H4.1301.00
65_L260_S4.1181.00
144_L202_L4.0111.00
482_V508_T3.9231.00
124_A185_V3.7901.00
387_D444_Y3.6451.00
172_D175_L3.5731.00
77_N98_K3.4441.00
58_I69_S2.9740.99
96_S197_D2.8440.99
422_I455_L2.8410.99
565_L597_L2.8300.99
489_A502_F2.8210.99
539_I593_S2.7580.99
22_I91_W2.7460.99
98_K195_G2.6620.99
416_Y485_S2.6360.98
261_H591_A2.6280.98
253_R256_L2.5780.98
487_L506_L2.5740.98
166_T188_A2.5700.98
460_V464_Y2.4960.98
251_L598_I2.4700.98
484_S509_V2.4640.98
173_G177_G2.3570.97
31_T331_V2.3440.97
169_D172_D2.2990.96
386_A444_Y2.2880.96
82_D93_R2.2300.96
253_R572_G2.2300.96
390_V447_V2.2230.96
250_I574_I2.1900.95
542_L564_V2.1680.95
437_E440_L2.1590.95
91_W202_L2.1520.95
63_D252_R2.1310.94
69_S82_D2.0980.94
109_T200_I2.0970.94
22_I202_L2.0950.94
556_K559_E2.0940.94
577_Q590_L2.0820.94
358_L424_G2.0660.93
96_S106_R2.0650.93
461_G464_Y2.0430.93
322_N501_R2.0020.92
251_L302_M2.0010.92
546_Q600_A1.9930.92
65_L256_L1.9560.91
70_S79_Y1.9470.91
66_A227_F1.9230.91
579_D582_D1.9180.90
68_Y79_Y1.9020.90
380_P384_G1.8790.90
518_G541_T1.8750.89
495_I502_F1.8740.89
83_V94_K1.8650.89
261_H272_L1.8570.89
383_K437_E1.8520.89
545_S600_A1.8400.89
446_T450_Q1.8160.88
43_F48_F1.8140.88
12_L89_D1.8060.88
323_G350_Q1.8040.87
232_D236_A1.7990.87
282_D328_K1.7930.87
587_V595_A1.7910.87
418_T455_L1.7540.86
351_E421_V1.7390.85
577_Q592_W1.7240.85
94_K197_D1.7110.84
22_I139_S1.7090.84
185_V191_F1.7070.84
518_G536_I1.7030.84
223_P299_L1.6910.84
366_S557_A1.6800.83
383_K438_D1.6790.83
355_A424_G1.6790.83
386_A425_L1.6720.83
512_K523_E1.6480.82
429_A448_A1.6410.82
41_G50_W1.6260.81
500_S504_K1.6180.81
40_F95_V1.6160.81
42_V78_F1.6140.81
165_G168_K1.6140.81
319_F385_I1.6130.81
541_T567_K1.6100.81
324_A354_T1.6060.80
492_F509_V1.5790.79
327_H339_W1.5700.79
351_E417_T1.5680.79
237_W259_Q1.5650.79
324_A349_I1.5520.78
422_I494_V1.5460.78
544_L548_Y1.5370.77
72_S77_N1.5370.77
255_L598_I1.5360.77
323_G525_D1.5320.77
390_V444_Y1.5270.77
74_E433_R1.5220.77
206_K210_E1.5010.76
258_L591_A1.4990.76
48_F53_N1.4880.75
295_C591_A1.4870.75
201_W223_P1.4850.75
156_G159_E1.4810.75
490_P547_V1.4780.74
510_I544_L1.4720.74
273_D328_K1.4700.74
64_T231_K1.4660.74
145_S215_S1.4630.74
169_D183_G1.4590.74
553_E556_K1.4590.74
463_H470_M1.4580.73
399_L451_M1.4550.73
441_A557_A1.4460.73
165_G170_C1.4410.73
413_T423_A1.4390.72
419_I489_A1.4380.72
169_D175_L1.4380.72
240_K306_D1.4100.71
110_A186_D1.4080.71
388_F421_V1.4070.71
173_G188_A1.4050.71
282_D339_W1.4020.70
406_L543_W1.3980.70
116_G120_D1.3830.69
350_Q537_W1.3690.69
59_G68_Y1.3660.68
173_G176_S1.3660.68
273_D282_D1.3650.68
143_L211_A1.3610.68
332_D604_L1.3540.68
172_D176_S1.3500.67
282_D286_Y1.3460.67
350_Q590_L1.3440.67
299_L539_I1.3440.67
245_G497_M1.3410.67
589_P594_H1.3390.67
65_L69_S1.3390.67
286_Y338_T1.3370.67
271_S313_E1.3250.66
441_A445_E1.3240.66
205_G214_L1.3210.66
83_V92_I1.3180.66
596_E599_R1.3160.65
35_L111_F1.3150.65
416_Y492_F1.3130.65
57_K70_S1.3080.65
257_I573_V1.3050.65
257_I497_M1.2980.64
352_D360_A1.2940.64
179_P182_Q1.2840.63
44_V47_K1.2780.63
282_D353_E1.2760.63
460_V463_H1.2760.63
352_D537_W1.2700.63
64_T256_L1.2590.62
428_A444_Y1.2580.62
55_N60_Y1.2560.62
28_P31_T1.2490.61
587_V592_W1.2430.61
514_S519_L1.2400.61
326_F329_Y1.2390.61
355_A358_L1.2390.61
383_K440_L1.2340.60
588_S591_A1.2340.60
423_A426_R1.2340.60
414_H428_A1.2300.60
557_A604_L1.2280.60
587_V590_L1.2280.60
191_F198_L1.2270.60
141_W208_Y1.2270.60
108_F190_S1.2160.59
537_W590_L1.2160.59
114_H122_N1.2090.59
166_T170_C1.2080.59
454_S457_L1.2060.58
261_H353_E1.2060.58
569_L588_S1.2040.58
224_A496_P1.2000.58
158_K165_G1.1990.58
97_V105_V1.1920.58
503_V507_E1.1870.57
502_F562_D1.1830.57
298_A598_I1.1720.56
247_Y601_I1.1700.56
83_V227_F1.1690.56
259_Q307_R1.1670.56
90_I218_V1.1670.56
165_G169_D1.1650.56
27_W89_D1.1650.56
71_F76_V1.1630.56
289_H339_W1.1600.55
386_A424_G1.1590.55
95_V191_F1.1590.55
132_S212_K1.1560.55
350_Q400_P1.1550.55
105_V239_S1.1530.55
459_W463_H1.1510.55
349_I388_F1.1460.55
350_Q592_W1.1450.54
546_Q599_R1.1450.54
237_W304_Y1.1430.54
455_L494_V1.1390.54
139_S144_L1.1370.54
308_S557_A1.1320.54
173_G190_S1.1280.53
482_V512_K1.1270.53
272_L285_N1.1260.53
323_G527_Y1.1240.53
58_I82_D1.1240.53
273_D587_V1.1210.53
106_R190_S1.1180.53
18_S23_R1.1180.53
547_V597_L1.1170.53
21_T272_L1.1140.52
323_G400_P1.1120.52
125_L134_I1.1110.52
71_F80_L1.1110.52
284_Y522_Y1.1090.52
537_W577_Q1.1070.52
330_T417_T1.0990.51
225_I229_R1.0990.51
237_W307_R1.0950.51
482_V509_V1.0910.51
187_F190_S1.0910.51
271_S542_L1.0900.51
24_E34_N1.0900.51
58_I67_A1.0880.51
269_V272_L1.0880.51
575_P590_L1.0850.50
546_Q603_A1.0840.50
261_H285_N1.0820.50
94_K199_Y1.0790.50
123_T447_V1.0760.50
323_G592_W1.0750.50
22_I242_N1.0750.50
412_G525_D1.0740.50
362_W427_A1.0730.50
385_I412_G1.0720.50
339_W350_Q1.0700.49
26_Y274_T1.0690.49
61_L64_T1.0690.49
592_W595_A1.0680.49
543_W593_S1.0670.49
25_I38_G1.0650.49
284_Y323_G1.0650.49
362_W431_F1.0640.49
590_L595_A1.0640.49
222_T226_L1.0600.49
382_V432_A1.0520.48
238_L256_L1.0490.48
350_Q595_A1.0480.48
423_A482_V1.0470.48
202_L207_N1.0470.48
315_T357_V1.0460.48
61_L72_S1.0420.48
536_I583_K1.0400.47
391_N462_D1.0400.47
50_W53_N1.0360.47
175_L180_I1.0330.47
272_L295_C1.0310.47
20_F69_S1.0290.47
115_V423_A1.0280.47
350_Q577_Q1.0270.47
319_F381_M1.0270.47
76_V549_S1.0260.47
250_I565_L1.0220.46
354_T385_I1.0200.46
319_F325_L1.0170.46
294_F416_Y1.0130.46
319_F580_D1.0120.46
294_F417_T1.0110.46
207_N503_V1.0110.46
260_S272_L1.0070.45
45_N48_F1.0050.45
185_V190_S1.0050.45
81_E227_F1.0040.45
111_F142_F1.0040.45
247_Y565_L1.0030.45
386_A448_A0.9980.45
169_D412_G0.9940.44
358_L389_L0.9920.44
70_S77_N0.9910.44
158_K186_D0.9880.44
243_D246_E0.9880.44
80_L85_D0.9870.44
288_W291_D0.9860.44
487_L490_P0.9830.44
408_E589_P0.9830.44
257_I594_H0.9730.43
536_I541_T0.9700.43
62_D249_S0.9700.43
460_V480_E0.9690.43
544_L579_D0.9640.42
24_E528_L0.9630.42
106_R207_N0.9570.42
374_I431_F0.9560.42
267_A534_S0.9560.42
552_G573_V0.9550.42
237_W255_L0.9550.42
574_I590_L0.9500.41
486_I505_N0.9490.41
268_I295_C0.9480.41
209_N454_S0.9460.41
154_A158_K0.9450.41
68_Y248_D0.9450.41
507_E511_E0.9440.41
455_L555_D0.9430.41
452_R495_I0.9420.41
323_G595_A0.9390.41
141_W515_V0.9370.41
244_Y248_D0.9340.40
419_I423_A0.9330.40
405_D412_G0.9320.40
352_D400_P0.9310.40
313_E317_R0.9270.40
330_T334_H0.9260.40
255_L593_S0.9240.40
14_V70_S0.9200.40
339_W525_D0.9170.39
462_D500_S0.9140.39
431_F435_F0.9110.39
489_A495_I0.9100.39
275_D357_V0.9090.39
460_V501_R0.9080.39
189_S202_L0.9060.39
389_L519_L0.9020.38
247_Y251_L0.9010.38
81_E94_K0.8970.38
500_S503_V0.8970.38
34_N518_G0.8910.38
464_Y497_M0.8910.38
417_T586_S0.8900.38
235_R252_R0.8900.38
236_A306_D0.8860.37
383_K502_F0.8790.37
254_S271_S0.8760.37
515_V536_I0.8730.37
602_Y606_N0.8720.37
47_K50_W0.8720.37
291_D483_D0.8710.36
286_Y328_K0.8700.36
338_T353_E0.8700.36
488_L506_L0.8690.36
178_N186_D0.8690.36
215_S321_I0.8690.36
416_Y483_D0.8670.36
397_T561_I0.8640.36
291_D576_E0.8640.36
415_F458_F0.8630.36
546_Q596_E0.8620.36
442_Q446_T0.8620.36
180_I185_V0.8590.36
54_L58_I0.8520.35
67_A71_F0.8520.35
484_S578_I0.8510.35
69_S261_H0.8510.35
447_V450_Q0.8500.35
429_A441_A0.8500.35
68_Y78_F0.8490.35
456_D460_V0.8480.35
372_D424_G0.8470.35
202_L484_S0.8430.35
28_P303_G0.8430.35
150_F189_S0.8400.35
596_E601_I0.8400.35
520_V536_I0.8370.34
255_L295_C0.8370.34
284_Y576_E0.8370.34
187_F191_F0.8350.34
116_G140_R0.8350.34
300_E582_D0.8350.34
261_H271_S0.8340.34
586_S592_W0.8340.34
323_G352_D0.8340.34
68_Y224_A0.8330.34
191_F194_Y0.8320.34
538_F574_I0.8320.34
147_P232_D0.8320.34
37_R110_A0.8320.34
391_N439_E0.8310.34
90_I513_L0.8300.34
270_A576_E0.8300.34
157_I161_K0.8280.34
26_Y261_H0.8270.34
483_D521_R0.8260.34
109_T226_L0.8250.34
200_I367_K0.8200.33
48_F454_S0.8190.33
61_L231_K0.8190.33
518_G537_W0.8160.33
225_I228_K0.8160.33
89_D210_E0.8150.33
322_N498_S0.8150.33
469_Y522_Y0.8140.33
552_G556_K0.8130.33
283_T339_W0.8120.33
349_I354_T0.8100.33
487_L544_L0.8090.33
527_Y537_W0.8070.33
282_D285_N0.8070.33
350_Q525_D0.8050.32
26_Y271_S0.8040.32
116_G494_V0.8030.32
501_R505_N0.7990.32
314_F329_Y0.7970.32
511_E555_D0.7960.32
236_A240_K0.7950.32
339_W400_P0.7920.32
84_I405_D0.7910.32
202_L593_S0.7900.32
78_F191_F0.7880.31
224_A497_M0.7870.31
244_Y601_I0.7840.31
55_N96_S0.7840.31
284_Y350_Q0.7810.31
350_Q527_Y0.7800.31
155_T187_F0.7800.31
539_I573_V0.7800.31
257_I589_P0.7770.31
175_L183_G0.7770.31
53_N207_N0.7770.31
183_G205_G0.7760.31
39_R43_F0.7760.31
284_Y291_D0.7760.31
216_D598_I0.7750.31
49_S53_N0.7750.31
206_K238_L0.7750.31
298_A578_I0.7740.31
192_K456_D0.7730.31
328_K338_T0.7730.31
26_Y353_E0.7720.31
71_F97_V0.7710.31
97_V206_K0.7700.30
385_I575_P0.7670.30
420_T424_G0.7670.30
479_D593_S0.7660.30
270_A291_D0.7660.30
136_Y389_L0.7630.30
405_D416_Y0.7620.30
112_D122_N0.7610.30
565_L602_Y0.7610.30
419_I525_D0.7590.30
383_K436_G0.7580.30
497_M574_I0.7560.30
339_W352_D0.7560.30
352_D595_A0.7550.30
273_D586_S0.7530.29
406_L542_L0.7530.29
189_S200_I0.7510.29
145_S462_D0.7500.29
60_Y117_G0.7500.29
226_L361_L0.7490.29
263_Q267_A0.7480.29
369_K424_G0.7480.29
288_W521_R0.7470.29
187_F200_I0.7460.29
569_L583_K0.7450.29
201_W219_R0.7440.29
118_T126_F0.7440.29
494_V530_G0.7430.29
22_I531_G0.7420.29
525_D592_W0.7420.29
362_W365_F0.7390.29
356_L591_A0.7380.29
525_D580_D0.7370.29
400_P525_D0.7370.29
228_K471_K0.7370.29
339_W574_I0.7360.29
261_H328_K0.7340.28
405_D409_E0.7340.28
327_H577_Q0.7340.28
166_T169_D0.7320.28
27_W195_G0.7320.28
234_W505_N0.7300.28
146_S160_Y0.7280.28
39_R485_S0.7270.28
169_D173_G0.7270.28
257_I575_P0.7260.28
519_L544_L0.7260.28
270_A408_E0.7230.28
146_S299_L0.7220.28
529_R535_N0.7210.28
236_A265_N0.7210.28
299_L560_K0.7210.28
571_T575_P0.7200.28
186_D190_S0.7200.28
17_D67_A0.7200.28
106_R205_G0.7200.28
172_D185_V0.7200.28
42_V377_Y0.7190.28
188_A193_L0.7190.28
20_F283_T0.7190.28
539_I564_V0.7170.28
412_G592_W0.7170.28
286_Y312_F0.7160.27
376_T431_F0.7160.27
390_V500_S0.7160.27
54_L64_T0.7160.27
358_L386_A0.7150.27
486_I545_S0.7140.27
186_D189_S0.7130.27
354_T403_S0.7130.27
282_D325_L0.7130.27
82_D261_H0.7130.27
299_L469_Y0.7120.27
46_G193_L0.7110.27
598_I605_R0.7110.27
210_E224_A0.7100.27
60_Y66_A0.7090.27
178_N507_E0.7090.27
284_Y408_E0.7090.27
24_E586_S0.7080.27
400_P537_W0.7060.27
293_V410_R0.7060.27
469_Y475_V0.7050.27
518_G567_K0.7040.27
86_M241_V0.7040.27
299_L483_D0.7010.27
205_G211_A0.7010.27
407_W521_R0.7010.27
228_K231_K0.7010.27
505_N549_S0.6990.27
408_E483_D0.6990.27
428_A589_P0.6970.26
296_I575_P0.6950.26
384_G547_V0.6950.26
226_L321_I0.6940.26
107_V195_G0.6940.26
109_T123_T0.6940.26
80_L93_R0.6910.26
196_E209_N0.6900.26
234_W517_R0.6900.26
323_G590_L0.6890.26
218_V561_I0.6880.26
488_L491_I0.6880.26
258_L598_I0.6880.26
389_L428_A0.6880.26
207_N239_S0.6870.26
527_Y592_W0.6840.26
136_Y518_G0.6840.26
172_D178_N0.6840.26
155_T158_K0.6820.26
307_R382_V0.6800.26
42_V206_K0.6800.26
24_E596_E0.6790.26
339_W577_Q0.6790.26
500_S598_I0.6790.26
528_L579_D0.6780.25
250_I254_S0.6780.25
29_L54_L0.6780.25
104_D192_K0.6780.25
480_E516_K0.6770.25
308_S482_V0.6760.25
256_L263_Q0.6760.25
251_L255_L0.6750.25
199_Y207_N0.6740.25
40_F258_L0.6740.25
211_A215_S0.6730.25
400_P448_A0.6710.25
97_V175_L0.6700.25
328_K354_T0.6700.25
195_G454_S0.6700.25
220_K455_L0.6690.25
408_E537_W0.6680.25
339_W590_L0.6680.25
24_E330_T0.6680.25
196_E449_D0.6670.25
408_E576_E0.6670.25
130_S202_L0.6670.25
327_H350_Q0.6670.25
156_G167_W0.6670.25
82_D543_W0.6650.25
492_F542_L0.6620.25
168_K172_D0.6610.25
112_D115_V0.6610.25
290_R576_E0.6600.25
586_S590_L0.6600.25
57_K249_S0.6600.25
276_I360_A0.6600.25
94_K232_D0.6590.25
328_K399_L0.6590.25
283_T330_T0.6580.24
271_S495_I0.6570.24
147_P443_K0.6570.24
328_K356_L0.6570.24
207_N210_E0.6560.24
170_C176_S0.6560.24
491_I599_R0.6540.24
457_L502_F0.6540.24
176_S480_E0.6540.24
35_L54_L0.6530.24
503_V551_M0.6520.24
288_W407_W0.6520.24
226_L428_A0.6510.24
380_P500_S0.6500.24
196_E207_N0.6500.24
95_V499_D0.6500.24
200_I302_M0.6500.24
83_V199_Y0.6490.24
491_I586_S0.6480.24
436_G552_G0.6460.24
49_S237_W0.6440.24
197_D220_K0.6430.24
132_S144_L0.6420.24
38_G497_M0.6420.24
418_T494_V0.6420.24
24_E276_I0.6420.24
24_E273_D0.6420.24
273_D339_W0.6420.24
327_H590_L0.6420.24
167_W170_C0.6410.24
104_D236_A0.6410.24
174_E207_N0.6410.24
180_I183_G0.6390.24
42_V455_L0.6390.24
140_R598_I0.6390.24
78_F550_L0.6380.24
188_A305_F0.6370.23
20_F85_D0.6370.23
290_R521_R0.6360.23
576_E589_P0.6360.23
213_G562_D0.6350.23
348_P593_S0.6350.23
150_F314_F0.6340.23
492_F599_R0.6340.23
274_T547_V0.6320.23
513_L594_H0.6310.23
601_I604_L0.6300.23
174_E512_K0.6300.23
142_F495_I0.6290.23
15_L389_L0.6290.23
412_G419_I0.6280.23
92_I226_L0.6280.23
64_T483_D0.6270.23
408_E521_R0.6270.23
16_Y20_F0.6260.23
258_L489_A0.6260.23
280_N417_T0.6250.23
577_Q587_V0.6240.23
259_Q278_K0.6240.23
89_D279_F0.6230.23
290_R483_D0.6220.23
325_L381_M0.6220.23
504_K508_T0.6220.23
335_F354_T0.6200.23
260_S459_W0.6200.23
218_V442_Q0.6190.23
464_Y494_V0.6190.23
97_V598_I0.6170.23
329_Y424_G0.6160.22
150_F391_N0.6150.22
21_T39_R0.6150.22
261_H295_C0.6150.22
266_G407_W0.6140.22
118_T361_L0.6140.22
297_L325_L0.6130.22
339_W354_T0.6110.22
209_N321_I0.6100.22
417_T587_V0.6100.22
493_N534_S0.6100.22
353_E587_V0.6090.22
400_P590_L0.6080.22
155_T562_D0.6070.22
250_I436_G0.6070.22
247_Y597_L0.6060.22
449_D532_N0.6060.22
331_V410_R0.6060.22
538_F564_V0.6050.22
327_H535_N0.6040.22
44_V52_D0.6040.22
107_V598_I0.6040.22
244_Y247_Y0.6040.22
110_A188_A0.6040.22
351_E469_Y0.6030.22
15_L272_L0.6030.22
237_W572_G0.6020.22
73_F76_V0.6020.22
16_Y582_D0.6000.22
224_A447_V0.5990.22
424_G428_A0.5980.22
456_D495_I0.5980.22
491_I543_W0.5970.22
282_D348_P0.5940.21
323_G385_I0.5930.21
460_V546_Q0.5920.21
518_G563_W0.5900.21
66_A147_P0.5880.21
412_G590_L0.5880.21
418_T458_F0.5870.21
77_N477_K0.5870.21
405_D592_W0.5870.21
209_N438_D0.5860.21
117_G418_T0.5860.21
379_R482_V0.5860.21
317_R431_F0.5850.21
289_H329_Y0.5850.21
584_Y588_S0.5850.21
499_D517_R0.5840.21
168_K171_E0.5830.21
291_D408_E0.5830.21
40_F358_L0.5820.21
79_Y565_L0.5820.21
288_W576_E0.5810.21
463_H479_D0.5800.21
503_V562_D0.5800.21
37_R71_F0.5790.21
487_L547_V0.5780.21
14_V17_D0.5760.21
104_D221_R0.5760.21
405_D527_Y0.5750.21
271_S370_D0.5750.21
245_G562_D0.5740.21
503_V509_V0.5730.21
574_I593_S0.5730.21
271_S507_E0.5710.20
55_N62_D0.5710.20
113_F118_T0.5710.20
362_W420_T0.5700.20
266_G270_A0.5700.20
130_S225_I0.5700.20
45_N531_G0.5700.20
52_D463_H0.5690.20
69_S272_L0.5690.20
300_E312_F0.5680.20
78_F107_V0.5660.20
476_H524_G0.5660.20
537_W595_A0.5660.20
179_P555_D0.5640.20
260_S573_V0.5640.20
282_D330_T0.5630.20
506_L551_M0.5630.20
255_L332_D0.5620.20
528_L544_L0.5620.20
21_T51_L0.5620.20
94_K533_N0.5620.20
248_D252_R0.5610.20
261_H552_G0.5600.20
282_D360_A0.5600.20
329_Y567_K0.5590.20
64_T494_V0.5590.20
184_S189_S0.5580.20
72_S79_Y0.5580.20
11_S14_V0.5560.20
97_V382_V0.5560.20
362_W426_R0.5560.20
310_Q313_E0.5550.20
505_N540_S0.5550.20
471_K536_I0.5550.20
386_A390_V0.5540.20
367_K562_D0.5540.20
69_S571_T0.5520.20
228_K375_K0.5520.20
71_F329_Y0.5510.20
459_W504_K0.5500.20
25_I593_S0.5500.20
398_G432_A0.5490.19
272_L540_S0.5480.19
353_E590_L0.5480.19
282_D338_T0.5470.19
63_D235_R0.5460.19
121_G593_S0.5460.19
505_N513_L0.5440.19
257_I374_I0.5440.19
86_M170_C0.5420.19
266_G290_R0.5410.19
427_A494_V0.5400.19
225_I433_R0.5390.19
553_E605_R0.5380.19
350_Q408_E0.5380.19
47_K52_D0.5380.19
292_A359_Y0.5370.19
207_N218_V0.5360.19
447_V451_M0.5360.19
52_D332_D0.5340.19
271_S591_A0.5340.19
34_N283_T0.5340.19
181_A184_S0.5330.19
405_D590_L0.5330.19
195_G506_L0.5330.19
153_Y428_A0.5310.19
12_L174_E0.5310.19
224_A239_S0.5310.19
504_K507_E0.5310.19
244_Y438_D0.5300.19
301_L493_N0.5300.19
310_Q449_D0.5300.19
558_K562_D0.5290.19
378_Y432_A0.5290.19
539_I596_E0.5280.19
175_L186_D0.5260.19
278_K302_M0.5250.19
327_H352_D0.5250.19
545_S556_K0.5240.18
380_P438_D0.5230.18
95_V198_L0.5220.18
412_G577_Q0.5220.18
409_E416_Y0.5210.18
60_Y82_D0.5210.18
211_A425_L0.5210.18
66_A232_D0.5200.18
522_Y575_P0.5200.18
591_A601_I0.5190.18
497_M544_L0.5190.18
65_L264_N0.5190.18
156_G525_D0.5190.18
286_Y353_E0.5180.18
185_V189_S0.5180.18
269_V545_S0.5170.18
311_F536_I0.5170.18
440_L484_S0.5170.18
387_D443_K0.5160.18
63_D98_K0.5160.18
36_H67_A0.5160.18
183_G186_D0.5160.18
382_V540_S0.5150.18
203_V549_S0.5140.18
537_W592_W0.5140.18
98_K104_D0.5140.18
463_H504_K0.5130.18
502_F510_I0.5130.18
328_K352_D0.5130.18
287_V416_Y0.5130.18
309_R313_E0.5120.18
57_K61_L0.5100.18
191_F516_K0.5090.18
40_F48_F0.5090.18
32_T237_W0.5080.18
96_S149_P0.5070.18
304_Y307_R0.5070.18
585_P591_A0.5060.18
59_G484_S0.5060.18
385_I389_L0.5060.18
298_A573_V0.5060.18
60_Y64_T0.5060.18
354_T518_G0.5060.18
258_L364_H0.5040.18
196_E306_D0.5030.18
60_Y69_S0.5030.18
275_D328_K0.5020.18
181_A431_F0.5020.18
505_N598_I0.5020.18
47_K236_A0.5010.18
132_S560_K0.5010.18
283_T528_L0.5010.18
63_D66_A0.5010.18
206_K209_N0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ulvA 1 0.9444 100 0.433 Contact Map
1lf6A 1 0.9477 100 0.457 Contact Map
2fbaA 1 0.6078 100 0.589 Contact Map
2vn4A 1 0.5605 100 0.616 Contact Map
1gaiA 1 0.5572 100 0.625 Contact Map
1v7wA 2 0.9461 100 0.708 Contact Map
3qryB 1 0.5915 100 0.71 Contact Map
3p2cA 2 0.6242 100 0.716 Contact Map
3qt9A 1 0.6013 100 0.721 Contact Map
2p0vA 2 0.6209 100 0.746 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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