Q97VY0 - SULSO - GREMLIN Contacts

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Q97VY0 - Glucan 1,4 alpha glucosidase (Glucoamylase)

UniProt:	Q97VY0	Sequences: MTRYLILGNGSLTVLYDSNFTIREIYWPLTTTNNLHRGRFGVFVNGKFSWLDNLNPKIGYLDDTLAAYSSFSFEGVNFYLEDVIDMAYDIWIRKVSVKDVKDRDVRVFTAFDFHVGGTPDGNTALFDPYSESMIQYKGSRWFLLSSPIPFYQYATGIKEYKGLLGTWKDCEDGELSGNPIAQGSVDFASSFKLYGEDLYIWLVAGKNYNEAKGLSDYVRKRTPAILFKRVKDYWRAWLSKVNDYGEYDSILRRSLLILQSHVQNNGAIVASLDTDIMKFNRDTYNYVWHRDAVFCILALELMGYFDRSRQFFEFTRRLFTINGALFHKYTVDGHFGSTWHPWTLDYLPIQEDETALVLYALWFHFSKWKDVDFIKTYYRPMVKGIADFLVNYREKATGLPLPSFDLWEERIGTHFYTTITVIAGLRAAADFARYFGEDELAQKYETVADQMRNSLDLFWVGDHYARTIYMKEGQVHKIDETVDSSILLAPIFNVIPMSDSRFVKNLETVIEKLSVKRGLVRYEGDQYLRGGNNSNIWFISTLWLSQVYSLMGEKDKAKEKIDWVLSKSLPTGVIPEQIDDNDKYPSVSPLAWSHAELIRAIYALRNGTLDPK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	612 (570)
Sequences:	640 (510)
Seq/√Len:	21.3

SULSO - Q97VY0 Q97ZD0 Q97V81 Q97V93

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
433_R	445_E	6.629	1.00
386_A	428_A	5.994	1.00
409_E	522_Y	5.609	1.00
255_L	302_M	5.133	1.00
254_S	594_H	4.884	1.00
426_R	445_E	4.396	1.00
300_E	364_H	4.130	1.00
65_L	260_S	4.118	1.00
144_L	202_L	4.011	1.00
482_V	508_T	3.923	1.00
124_A	185_V	3.790	1.00
387_D	444_Y	3.645	1.00
172_D	175_L	3.573	1.00
77_N	98_K	3.444	1.00
58_I	69_S	2.974	0.99
96_S	197_D	2.844	0.99
422_I	455_L	2.841	0.99
565_L	597_L	2.830	0.99
489_A	502_F	2.821	0.99
539_I	593_S	2.758	0.99
22_I	91_W	2.746	0.99
98_K	195_G	2.662	0.99
416_Y	485_S	2.636	0.98
261_H	591_A	2.628	0.98
253_R	256_L	2.578	0.98
487_L	506_L	2.574	0.98
166_T	188_A	2.570	0.98
460_V	464_Y	2.496	0.98
251_L	598_I	2.470	0.98
484_S	509_V	2.464	0.98
173_G	177_G	2.357	0.97
31_T	331_V	2.344	0.97
169_D	172_D	2.299	0.96
386_A	444_Y	2.288	0.96
82_D	93_R	2.230	0.96
253_R	572_G	2.230	0.96
390_V	447_V	2.223	0.96
250_I	574_I	2.190	0.95
542_L	564_V	2.168	0.95
437_E	440_L	2.159	0.95
91_W	202_L	2.152	0.95
63_D	252_R	2.131	0.94
69_S	82_D	2.098	0.94
109_T	200_I	2.097	0.94
22_I	202_L	2.095	0.94
556_K	559_E	2.094	0.94
577_Q	590_L	2.082	0.94
358_L	424_G	2.066	0.93
96_S	106_R	2.065	0.93
461_G	464_Y	2.043	0.93
322_N	501_R	2.002	0.92
251_L	302_M	2.001	0.92
546_Q	600_A	1.993	0.92
65_L	256_L	1.956	0.91
70_S	79_Y	1.947	0.91
66_A	227_F	1.923	0.91
579_D	582_D	1.918	0.90
68_Y	79_Y	1.902	0.90
380_P	384_G	1.879	0.90
518_G	541_T	1.875	0.89
495_I	502_F	1.874	0.89
83_V	94_K	1.865	0.89
261_H	272_L	1.857	0.89
383_K	437_E	1.852	0.89
545_S	600_A	1.840	0.89
446_T	450_Q	1.816	0.88
43_F	48_F	1.814	0.88
12_L	89_D	1.806	0.88
323_G	350_Q	1.804	0.87
232_D	236_A	1.799	0.87
282_D	328_K	1.793	0.87
587_V	595_A	1.791	0.87
418_T	455_L	1.754	0.86
351_E	421_V	1.739	0.85
577_Q	592_W	1.724	0.85
94_K	197_D	1.711	0.84
22_I	139_S	1.709	0.84
185_V	191_F	1.707	0.84
518_G	536_I	1.703	0.84
223_P	299_L	1.691	0.84
366_S	557_A	1.680	0.83
383_K	438_D	1.679	0.83
355_A	424_G	1.679	0.83
386_A	425_L	1.672	0.83
512_K	523_E	1.648	0.82
429_A	448_A	1.641	0.82
41_G	50_W	1.626	0.81
500_S	504_K	1.618	0.81
40_F	95_V	1.616	0.81
42_V	78_F	1.614	0.81
165_G	168_K	1.614	0.81
319_F	385_I	1.613	0.81
541_T	567_K	1.610	0.81
324_A	354_T	1.606	0.80
492_F	509_V	1.579	0.79
327_H	339_W	1.570	0.79
351_E	417_T	1.568	0.79
237_W	259_Q	1.565	0.79
324_A	349_I	1.552	0.78
422_I	494_V	1.546	0.78
544_L	548_Y	1.537	0.77
72_S	77_N	1.537	0.77
255_L	598_I	1.536	0.77
323_G	525_D	1.532	0.77
390_V	444_Y	1.527	0.77
74_E	433_R	1.522	0.77
206_K	210_E	1.501	0.76
258_L	591_A	1.499	0.76
48_F	53_N	1.488	0.75
295_C	591_A	1.487	0.75
201_W	223_P	1.485	0.75
156_G	159_E	1.481	0.75
490_P	547_V	1.478	0.74
510_I	544_L	1.472	0.74
273_D	328_K	1.470	0.74
64_T	231_K	1.466	0.74
145_S	215_S	1.463	0.74
169_D	183_G	1.459	0.74
553_E	556_K	1.459	0.74
463_H	470_M	1.458	0.73
399_L	451_M	1.455	0.73
441_A	557_A	1.446	0.73
165_G	170_C	1.441	0.73
413_T	423_A	1.439	0.72
419_I	489_A	1.438	0.72
169_D	175_L	1.438	0.72
240_K	306_D	1.410	0.71
110_A	186_D	1.408	0.71
388_F	421_V	1.407	0.71
173_G	188_A	1.405	0.71
282_D	339_W	1.402	0.70
406_L	543_W	1.398	0.70
116_G	120_D	1.383	0.69
350_Q	537_W	1.369	0.69
59_G	68_Y	1.366	0.68
173_G	176_S	1.366	0.68
273_D	282_D	1.365	0.68
143_L	211_A	1.361	0.68
332_D	604_L	1.354	0.68
172_D	176_S	1.350	0.67
282_D	286_Y	1.346	0.67
350_Q	590_L	1.344	0.67
299_L	539_I	1.344	0.67
245_G	497_M	1.341	0.67
589_P	594_H	1.339	0.67
65_L	69_S	1.339	0.67
286_Y	338_T	1.337	0.67
271_S	313_E	1.325	0.66
441_A	445_E	1.324	0.66
205_G	214_L	1.321	0.66
83_V	92_I	1.318	0.66
596_E	599_R	1.316	0.65
35_L	111_F	1.315	0.65
416_Y	492_F	1.313	0.65
57_K	70_S	1.308	0.65
257_I	573_V	1.305	0.65
257_I	497_M	1.298	0.64
352_D	360_A	1.294	0.64
179_P	182_Q	1.284	0.63
44_V	47_K	1.278	0.63
282_D	353_E	1.276	0.63
460_V	463_H	1.276	0.63
352_D	537_W	1.270	0.63
64_T	256_L	1.259	0.62
428_A	444_Y	1.258	0.62
55_N	60_Y	1.256	0.62
28_P	31_T	1.249	0.61
587_V	592_W	1.243	0.61
514_S	519_L	1.240	0.61
326_F	329_Y	1.239	0.61
355_A	358_L	1.239	0.61
383_K	440_L	1.234	0.60
588_S	591_A	1.234	0.60
423_A	426_R	1.234	0.60
414_H	428_A	1.230	0.60
557_A	604_L	1.228	0.60
587_V	590_L	1.228	0.60
191_F	198_L	1.227	0.60
141_W	208_Y	1.227	0.60
108_F	190_S	1.216	0.59
537_W	590_L	1.216	0.59
114_H	122_N	1.209	0.59
166_T	170_C	1.208	0.59
454_S	457_L	1.206	0.58
261_H	353_E	1.206	0.58
569_L	588_S	1.204	0.58
224_A	496_P	1.200	0.58
158_K	165_G	1.199	0.58
97_V	105_V	1.192	0.58
503_V	507_E	1.187	0.57
502_F	562_D	1.183	0.57
298_A	598_I	1.172	0.56
247_Y	601_I	1.170	0.56
83_V	227_F	1.169	0.56
259_Q	307_R	1.167	0.56
90_I	218_V	1.167	0.56
165_G	169_D	1.165	0.56
27_W	89_D	1.165	0.56
71_F	76_V	1.163	0.56
289_H	339_W	1.160	0.55
386_A	424_G	1.159	0.55
95_V	191_F	1.159	0.55
132_S	212_K	1.156	0.55
350_Q	400_P	1.155	0.55
105_V	239_S	1.153	0.55
459_W	463_H	1.151	0.55
349_I	388_F	1.146	0.55
350_Q	592_W	1.145	0.54
546_Q	599_R	1.145	0.54
237_W	304_Y	1.143	0.54
455_L	494_V	1.139	0.54
139_S	144_L	1.137	0.54
308_S	557_A	1.132	0.54
173_G	190_S	1.128	0.53
482_V	512_K	1.127	0.53
272_L	285_N	1.126	0.53
323_G	527_Y	1.124	0.53
58_I	82_D	1.124	0.53
273_D	587_V	1.121	0.53
106_R	190_S	1.118	0.53
18_S	23_R	1.118	0.53
547_V	597_L	1.117	0.53
21_T	272_L	1.114	0.52
323_G	400_P	1.112	0.52
125_L	134_I	1.111	0.52
71_F	80_L	1.111	0.52
284_Y	522_Y	1.109	0.52
537_W	577_Q	1.107	0.52
330_T	417_T	1.099	0.51
225_I	229_R	1.099	0.51
237_W	307_R	1.095	0.51
482_V	509_V	1.091	0.51
187_F	190_S	1.091	0.51
271_S	542_L	1.090	0.51
24_E	34_N	1.090	0.51
58_I	67_A	1.088	0.51
269_V	272_L	1.088	0.51
575_P	590_L	1.085	0.50
546_Q	603_A	1.084	0.50
261_H	285_N	1.082	0.50
94_K	199_Y	1.079	0.50
123_T	447_V	1.076	0.50
323_G	592_W	1.075	0.50
22_I	242_N	1.075	0.50
412_G	525_D	1.074	0.50
362_W	427_A	1.073	0.50
385_I	412_G	1.072	0.50
339_W	350_Q	1.070	0.49
26_Y	274_T	1.069	0.49
61_L	64_T	1.069	0.49
592_W	595_A	1.068	0.49
543_W	593_S	1.067	0.49
25_I	38_G	1.065	0.49
284_Y	323_G	1.065	0.49
362_W	431_F	1.064	0.49
590_L	595_A	1.064	0.49
222_T	226_L	1.060	0.49
382_V	432_A	1.052	0.48
238_L	256_L	1.049	0.48
350_Q	595_A	1.048	0.48
423_A	482_V	1.047	0.48
202_L	207_N	1.047	0.48
315_T	357_V	1.046	0.48
61_L	72_S	1.042	0.48
536_I	583_K	1.040	0.47
391_N	462_D	1.040	0.47
50_W	53_N	1.036	0.47
175_L	180_I	1.033	0.47
272_L	295_C	1.031	0.47
20_F	69_S	1.029	0.47
115_V	423_A	1.028	0.47
350_Q	577_Q	1.027	0.47
319_F	381_M	1.027	0.47
76_V	549_S	1.026	0.47
250_I	565_L	1.022	0.46
354_T	385_I	1.020	0.46
319_F	325_L	1.017	0.46
294_F	416_Y	1.013	0.46
319_F	580_D	1.012	0.46
294_F	417_T	1.011	0.46
207_N	503_V	1.011	0.46
260_S	272_L	1.007	0.45
45_N	48_F	1.005	0.45
185_V	190_S	1.005	0.45
81_E	227_F	1.004	0.45
111_F	142_F	1.004	0.45
247_Y	565_L	1.003	0.45
386_A	448_A	0.998	0.45
169_D	412_G	0.994	0.44
358_L	389_L	0.992	0.44
70_S	77_N	0.991	0.44
158_K	186_D	0.988	0.44
243_D	246_E	0.988	0.44
80_L	85_D	0.987	0.44
288_W	291_D	0.986	0.44
487_L	490_P	0.983	0.44
408_E	589_P	0.983	0.44
257_I	594_H	0.973	0.43
536_I	541_T	0.970	0.43
62_D	249_S	0.970	0.43
460_V	480_E	0.969	0.43
544_L	579_D	0.964	0.42
24_E	528_L	0.963	0.42
106_R	207_N	0.957	0.42
374_I	431_F	0.956	0.42
267_A	534_S	0.956	0.42
552_G	573_V	0.955	0.42
237_W	255_L	0.955	0.42
574_I	590_L	0.950	0.41
486_I	505_N	0.949	0.41
268_I	295_C	0.948	0.41
209_N	454_S	0.946	0.41
154_A	158_K	0.945	0.41
68_Y	248_D	0.945	0.41
507_E	511_E	0.944	0.41
455_L	555_D	0.943	0.41
452_R	495_I	0.942	0.41
323_G	595_A	0.939	0.41
141_W	515_V	0.937	0.41
244_Y	248_D	0.934	0.40
419_I	423_A	0.933	0.40
405_D	412_G	0.932	0.40
352_D	400_P	0.931	0.40
313_E	317_R	0.927	0.40
330_T	334_H	0.926	0.40
255_L	593_S	0.924	0.40
14_V	70_S	0.920	0.40
339_W	525_D	0.917	0.39
462_D	500_S	0.914	0.39
431_F	435_F	0.911	0.39
489_A	495_I	0.910	0.39
275_D	357_V	0.909	0.39
460_V	501_R	0.908	0.39
189_S	202_L	0.906	0.39
389_L	519_L	0.902	0.38
247_Y	251_L	0.901	0.38
81_E	94_K	0.897	0.38
500_S	503_V	0.897	0.38
34_N	518_G	0.891	0.38
464_Y	497_M	0.891	0.38
417_T	586_S	0.890	0.38
235_R	252_R	0.890	0.38
236_A	306_D	0.886	0.37
383_K	502_F	0.879	0.37
254_S	271_S	0.876	0.37
515_V	536_I	0.873	0.37
602_Y	606_N	0.872	0.37
47_K	50_W	0.872	0.37
291_D	483_D	0.871	0.36
286_Y	328_K	0.870	0.36
338_T	353_E	0.870	0.36
488_L	506_L	0.869	0.36
178_N	186_D	0.869	0.36
215_S	321_I	0.869	0.36
416_Y	483_D	0.867	0.36
397_T	561_I	0.864	0.36
291_D	576_E	0.864	0.36
415_F	458_F	0.863	0.36
546_Q	596_E	0.862	0.36
442_Q	446_T	0.862	0.36
180_I	185_V	0.859	0.36
54_L	58_I	0.852	0.35
67_A	71_F	0.852	0.35
484_S	578_I	0.851	0.35
69_S	261_H	0.851	0.35
447_V	450_Q	0.850	0.35
429_A	441_A	0.850	0.35
68_Y	78_F	0.849	0.35
456_D	460_V	0.848	0.35
372_D	424_G	0.847	0.35
202_L	484_S	0.843	0.35
28_P	303_G	0.843	0.35
150_F	189_S	0.840	0.35
596_E	601_I	0.840	0.35
520_V	536_I	0.837	0.34
255_L	295_C	0.837	0.34
284_Y	576_E	0.837	0.34
187_F	191_F	0.835	0.34
116_G	140_R	0.835	0.34
300_E	582_D	0.835	0.34
261_H	271_S	0.834	0.34
586_S	592_W	0.834	0.34
323_G	352_D	0.834	0.34
68_Y	224_A	0.833	0.34
191_F	194_Y	0.832	0.34
538_F	574_I	0.832	0.34
147_P	232_D	0.832	0.34
37_R	110_A	0.832	0.34
391_N	439_E	0.831	0.34
90_I	513_L	0.830	0.34
270_A	576_E	0.830	0.34
157_I	161_K	0.828	0.34
26_Y	261_H	0.827	0.34
483_D	521_R	0.826	0.34
109_T	226_L	0.825	0.34
200_I	367_K	0.820	0.33
48_F	454_S	0.819	0.33
61_L	231_K	0.819	0.33
518_G	537_W	0.816	0.33
225_I	228_K	0.816	0.33
89_D	210_E	0.815	0.33
322_N	498_S	0.815	0.33
469_Y	522_Y	0.814	0.33
552_G	556_K	0.813	0.33
283_T	339_W	0.812	0.33
349_I	354_T	0.810	0.33
487_L	544_L	0.809	0.33
527_Y	537_W	0.807	0.33
282_D	285_N	0.807	0.33
350_Q	525_D	0.805	0.32
26_Y	271_S	0.804	0.32
116_G	494_V	0.803	0.32
501_R	505_N	0.799	0.32
314_F	329_Y	0.797	0.32
511_E	555_D	0.796	0.32
236_A	240_K	0.795	0.32
339_W	400_P	0.792	0.32
84_I	405_D	0.791	0.32
202_L	593_S	0.790	0.32
78_F	191_F	0.788	0.31
224_A	497_M	0.787	0.31
244_Y	601_I	0.784	0.31
55_N	96_S	0.784	0.31
284_Y	350_Q	0.781	0.31
350_Q	527_Y	0.780	0.31
155_T	187_F	0.780	0.31
539_I	573_V	0.780	0.31
257_I	589_P	0.777	0.31
175_L	183_G	0.777	0.31
53_N	207_N	0.777	0.31
183_G	205_G	0.776	0.31
39_R	43_F	0.776	0.31
284_Y	291_D	0.776	0.31
216_D	598_I	0.775	0.31
49_S	53_N	0.775	0.31
206_K	238_L	0.775	0.31
298_A	578_I	0.774	0.31
192_K	456_D	0.773	0.31
328_K	338_T	0.773	0.31
26_Y	353_E	0.772	0.31
71_F	97_V	0.771	0.31
97_V	206_K	0.770	0.30
385_I	575_P	0.767	0.30
420_T	424_G	0.767	0.30
479_D	593_S	0.766	0.30
270_A	291_D	0.766	0.30
136_Y	389_L	0.763	0.30
405_D	416_Y	0.762	0.30
112_D	122_N	0.761	0.30
565_L	602_Y	0.761	0.30
419_I	525_D	0.759	0.30
383_K	436_G	0.758	0.30
497_M	574_I	0.756	0.30
339_W	352_D	0.756	0.30
352_D	595_A	0.755	0.30
273_D	586_S	0.753	0.29
406_L	542_L	0.753	0.29
189_S	200_I	0.751	0.29
145_S	462_D	0.750	0.29
60_Y	117_G	0.750	0.29
226_L	361_L	0.749	0.29
263_Q	267_A	0.748	0.29
369_K	424_G	0.748	0.29
288_W	521_R	0.747	0.29
187_F	200_I	0.746	0.29
569_L	583_K	0.745	0.29
201_W	219_R	0.744	0.29
118_T	126_F	0.744	0.29
494_V	530_G	0.743	0.29
22_I	531_G	0.742	0.29
525_D	592_W	0.742	0.29
362_W	365_F	0.739	0.29
356_L	591_A	0.738	0.29
525_D	580_D	0.737	0.29
400_P	525_D	0.737	0.29
228_K	471_K	0.737	0.29
339_W	574_I	0.736	0.29
261_H	328_K	0.734	0.28
405_D	409_E	0.734	0.28
327_H	577_Q	0.734	0.28
166_T	169_D	0.732	0.28
27_W	195_G	0.732	0.28
234_W	505_N	0.730	0.28
146_S	160_Y	0.728	0.28
39_R	485_S	0.727	0.28
169_D	173_G	0.727	0.28
257_I	575_P	0.726	0.28
519_L	544_L	0.726	0.28
270_A	408_E	0.723	0.28
146_S	299_L	0.722	0.28
529_R	535_N	0.721	0.28
236_A	265_N	0.721	0.28
299_L	560_K	0.721	0.28
571_T	575_P	0.720	0.28
186_D	190_S	0.720	0.28
17_D	67_A	0.720	0.28
106_R	205_G	0.720	0.28
172_D	185_V	0.720	0.28
42_V	377_Y	0.719	0.28
188_A	193_L	0.719	0.28
20_F	283_T	0.719	0.28
539_I	564_V	0.717	0.28
412_G	592_W	0.717	0.28
286_Y	312_F	0.716	0.27
376_T	431_F	0.716	0.27
390_V	500_S	0.716	0.27
54_L	64_T	0.716	0.27
358_L	386_A	0.715	0.27
486_I	545_S	0.714	0.27
186_D	189_S	0.713	0.27
354_T	403_S	0.713	0.27
282_D	325_L	0.713	0.27
82_D	261_H	0.713	0.27
299_L	469_Y	0.712	0.27
46_G	193_L	0.711	0.27
598_I	605_R	0.711	0.27
210_E	224_A	0.710	0.27
60_Y	66_A	0.709	0.27
178_N	507_E	0.709	0.27
284_Y	408_E	0.709	0.27
24_E	586_S	0.708	0.27
400_P	537_W	0.706	0.27
293_V	410_R	0.706	0.27
469_Y	475_V	0.705	0.27
518_G	567_K	0.704	0.27
86_M	241_V	0.704	0.27
299_L	483_D	0.701	0.27
205_G	211_A	0.701	0.27
407_W	521_R	0.701	0.27
228_K	231_K	0.701	0.27
505_N	549_S	0.699	0.27
408_E	483_D	0.699	0.27
428_A	589_P	0.697	0.26
296_I	575_P	0.695	0.26
384_G	547_V	0.695	0.26
226_L	321_I	0.694	0.26
107_V	195_G	0.694	0.26
109_T	123_T	0.694	0.26
80_L	93_R	0.691	0.26
196_E	209_N	0.690	0.26
234_W	517_R	0.690	0.26
323_G	590_L	0.689	0.26
218_V	561_I	0.688	0.26
488_L	491_I	0.688	0.26
258_L	598_I	0.688	0.26
389_L	428_A	0.688	0.26
207_N	239_S	0.687	0.26
527_Y	592_W	0.684	0.26
136_Y	518_G	0.684	0.26
172_D	178_N	0.684	0.26
155_T	158_K	0.682	0.26
307_R	382_V	0.680	0.26
42_V	206_K	0.680	0.26
24_E	596_E	0.679	0.26
339_W	577_Q	0.679	0.26
500_S	598_I	0.679	0.26
528_L	579_D	0.678	0.25
250_I	254_S	0.678	0.25
29_L	54_L	0.678	0.25
104_D	192_K	0.678	0.25
480_E	516_K	0.677	0.25
308_S	482_V	0.676	0.25
256_L	263_Q	0.676	0.25
251_L	255_L	0.675	0.25
199_Y	207_N	0.674	0.25
40_F	258_L	0.674	0.25
211_A	215_S	0.673	0.25
400_P	448_A	0.671	0.25
97_V	175_L	0.670	0.25
328_K	354_T	0.670	0.25
195_G	454_S	0.670	0.25
220_K	455_L	0.669	0.25
408_E	537_W	0.668	0.25
339_W	590_L	0.668	0.25
24_E	330_T	0.668	0.25
196_E	449_D	0.667	0.25
408_E	576_E	0.667	0.25
130_S	202_L	0.667	0.25
327_H	350_Q	0.667	0.25
156_G	167_W	0.667	0.25
82_D	543_W	0.665	0.25
492_F	542_L	0.662	0.25
168_K	172_D	0.661	0.25
112_D	115_V	0.661	0.25
290_R	576_E	0.660	0.25
586_S	590_L	0.660	0.25
57_K	249_S	0.660	0.25
276_I	360_A	0.660	0.25
94_K	232_D	0.659	0.25
328_K	399_L	0.659	0.25
283_T	330_T	0.658	0.24
271_S	495_I	0.657	0.24
147_P	443_K	0.657	0.24
328_K	356_L	0.657	0.24
207_N	210_E	0.656	0.24
170_C	176_S	0.656	0.24
491_I	599_R	0.654	0.24
457_L	502_F	0.654	0.24
176_S	480_E	0.654	0.24
35_L	54_L	0.653	0.24
503_V	551_M	0.652	0.24
288_W	407_W	0.652	0.24
226_L	428_A	0.651	0.24
380_P	500_S	0.650	0.24
196_E	207_N	0.650	0.24
95_V	499_D	0.650	0.24
200_I	302_M	0.650	0.24
83_V	199_Y	0.649	0.24
491_I	586_S	0.648	0.24
436_G	552_G	0.646	0.24
49_S	237_W	0.644	0.24
197_D	220_K	0.643	0.24
132_S	144_L	0.642	0.24
38_G	497_M	0.642	0.24
418_T	494_V	0.642	0.24
24_E	276_I	0.642	0.24
24_E	273_D	0.642	0.24
273_D	339_W	0.642	0.24
327_H	590_L	0.642	0.24
167_W	170_C	0.641	0.24
104_D	236_A	0.641	0.24
174_E	207_N	0.641	0.24
180_I	183_G	0.639	0.24
42_V	455_L	0.639	0.24
140_R	598_I	0.639	0.24
78_F	550_L	0.638	0.24
188_A	305_F	0.637	0.23
20_F	85_D	0.637	0.23
290_R	521_R	0.636	0.23
576_E	589_P	0.636	0.23
213_G	562_D	0.635	0.23
348_P	593_S	0.635	0.23
150_F	314_F	0.634	0.23
492_F	599_R	0.634	0.23
274_T	547_V	0.632	0.23
513_L	594_H	0.631	0.23
601_I	604_L	0.630	0.23
174_E	512_K	0.630	0.23
142_F	495_I	0.629	0.23
15_L	389_L	0.629	0.23
412_G	419_I	0.628	0.23
92_I	226_L	0.628	0.23
64_T	483_D	0.627	0.23
408_E	521_R	0.627	0.23
16_Y	20_F	0.626	0.23
258_L	489_A	0.626	0.23
280_N	417_T	0.625	0.23
577_Q	587_V	0.624	0.23
259_Q	278_K	0.624	0.23
89_D	279_F	0.623	0.23
290_R	483_D	0.622	0.23
325_L	381_M	0.622	0.23
504_K	508_T	0.622	0.23
335_F	354_T	0.620	0.23
260_S	459_W	0.620	0.23
218_V	442_Q	0.619	0.23
464_Y	494_V	0.619	0.23
97_V	598_I	0.617	0.23
329_Y	424_G	0.616	0.22
150_F	391_N	0.615	0.22
21_T	39_R	0.615	0.22
261_H	295_C	0.615	0.22
266_G	407_W	0.614	0.22
118_T	361_L	0.614	0.22
297_L	325_L	0.613	0.22
339_W	354_T	0.611	0.22
209_N	321_I	0.610	0.22
417_T	587_V	0.610	0.22
493_N	534_S	0.610	0.22
353_E	587_V	0.609	0.22
400_P	590_L	0.608	0.22
155_T	562_D	0.607	0.22
250_I	436_G	0.607	0.22
247_Y	597_L	0.606	0.22
449_D	532_N	0.606	0.22
331_V	410_R	0.606	0.22
538_F	564_V	0.605	0.22
327_H	535_N	0.604	0.22
44_V	52_D	0.604	0.22
107_V	598_I	0.604	0.22
244_Y	247_Y	0.604	0.22
110_A	188_A	0.604	0.22
351_E	469_Y	0.603	0.22
15_L	272_L	0.603	0.22
237_W	572_G	0.602	0.22
73_F	76_V	0.602	0.22
16_Y	582_D	0.600	0.22
224_A	447_V	0.599	0.22
424_G	428_A	0.598	0.22
456_D	495_I	0.598	0.22
491_I	543_W	0.597	0.22
282_D	348_P	0.594	0.21
323_G	385_I	0.593	0.21
460_V	546_Q	0.592	0.21
518_G	563_W	0.590	0.21
66_A	147_P	0.588	0.21
412_G	590_L	0.588	0.21
418_T	458_F	0.587	0.21
77_N	477_K	0.587	0.21
405_D	592_W	0.587	0.21
209_N	438_D	0.586	0.21
117_G	418_T	0.586	0.21
379_R	482_V	0.586	0.21
317_R	431_F	0.585	0.21
289_H	329_Y	0.585	0.21
584_Y	588_S	0.585	0.21
499_D	517_R	0.584	0.21
168_K	171_E	0.583	0.21
291_D	408_E	0.583	0.21
40_F	358_L	0.582	0.21
79_Y	565_L	0.582	0.21
288_W	576_E	0.581	0.21
463_H	479_D	0.580	0.21
503_V	562_D	0.580	0.21
37_R	71_F	0.579	0.21
487_L	547_V	0.578	0.21
14_V	17_D	0.576	0.21
104_D	221_R	0.576	0.21
405_D	527_Y	0.575	0.21
271_S	370_D	0.575	0.21
245_G	562_D	0.574	0.21
503_V	509_V	0.573	0.21
574_I	593_S	0.573	0.21
271_S	507_E	0.571	0.20
55_N	62_D	0.571	0.20
113_F	118_T	0.571	0.20
362_W	420_T	0.570	0.20
266_G	270_A	0.570	0.20
130_S	225_I	0.570	0.20
45_N	531_G	0.570	0.20
52_D	463_H	0.569	0.20
69_S	272_L	0.569	0.20
300_E	312_F	0.568	0.20
78_F	107_V	0.566	0.20
476_H	524_G	0.566	0.20
537_W	595_A	0.566	0.20
179_P	555_D	0.564	0.20
260_S	573_V	0.564	0.20
282_D	330_T	0.563	0.20
506_L	551_M	0.563	0.20
255_L	332_D	0.562	0.20
528_L	544_L	0.562	0.20
21_T	51_L	0.562	0.20
94_K	533_N	0.562	0.20
248_D	252_R	0.561	0.20
261_H	552_G	0.560	0.20
282_D	360_A	0.560	0.20
329_Y	567_K	0.559	0.20
64_T	494_V	0.559	0.20
184_S	189_S	0.558	0.20
72_S	79_Y	0.558	0.20
11_S	14_V	0.556	0.20
97_V	382_V	0.556	0.20
362_W	426_R	0.556	0.20
310_Q	313_E	0.555	0.20
505_N	540_S	0.555	0.20
471_K	536_I	0.555	0.20
386_A	390_V	0.554	0.20
367_K	562_D	0.554	0.20
69_S	571_T	0.552	0.20
228_K	375_K	0.552	0.20
71_F	329_Y	0.551	0.20
459_W	504_K	0.550	0.20
25_I	593_S	0.550	0.20
398_G	432_A	0.549	0.19
272_L	540_S	0.548	0.19
353_E	590_L	0.548	0.19
282_D	338_T	0.547	0.19
63_D	235_R	0.546	0.19
121_G	593_S	0.546	0.19
505_N	513_L	0.544	0.19
257_I	374_I	0.544	0.19
86_M	170_C	0.542	0.19
266_G	290_R	0.541	0.19
427_A	494_V	0.540	0.19
225_I	433_R	0.539	0.19
553_E	605_R	0.538	0.19
350_Q	408_E	0.538	0.19
47_K	52_D	0.538	0.19
292_A	359_Y	0.537	0.19
207_N	218_V	0.536	0.19
447_V	451_M	0.536	0.19
52_D	332_D	0.534	0.19
271_S	591_A	0.534	0.19
34_N	283_T	0.534	0.19
181_A	184_S	0.533	0.19
405_D	590_L	0.533	0.19
195_G	506_L	0.533	0.19
153_Y	428_A	0.531	0.19
12_L	174_E	0.531	0.19
224_A	239_S	0.531	0.19
504_K	507_E	0.531	0.19
244_Y	438_D	0.530	0.19
301_L	493_N	0.530	0.19
310_Q	449_D	0.530	0.19
558_K	562_D	0.529	0.19
378_Y	432_A	0.529	0.19
539_I	596_E	0.528	0.19
175_L	186_D	0.526	0.19
278_K	302_M	0.525	0.19
327_H	352_D	0.525	0.19
545_S	556_K	0.524	0.18
380_P	438_D	0.523	0.18
95_V	198_L	0.522	0.18
412_G	577_Q	0.522	0.18
409_E	416_Y	0.521	0.18
60_Y	82_D	0.521	0.18
211_A	425_L	0.521	0.18
66_A	232_D	0.520	0.18
522_Y	575_P	0.520	0.18
591_A	601_I	0.519	0.18
497_M	544_L	0.519	0.18
65_L	264_N	0.519	0.18
156_G	525_D	0.519	0.18
286_Y	353_E	0.518	0.18
185_V	189_S	0.518	0.18
269_V	545_S	0.517	0.18
311_F	536_I	0.517	0.18
440_L	484_S	0.517	0.18
387_D	443_K	0.516	0.18
63_D	98_K	0.516	0.18
36_H	67_A	0.516	0.18
183_G	186_D	0.516	0.18
382_V	540_S	0.515	0.18
203_V	549_S	0.514	0.18
537_W	592_W	0.514	0.18
98_K	104_D	0.514	0.18
463_H	504_K	0.513	0.18
502_F	510_I	0.513	0.18
328_K	352_D	0.513	0.18
287_V	416_Y	0.513	0.18
309_R	313_E	0.512	0.18
57_K	61_L	0.510	0.18
191_F	516_K	0.509	0.18
40_F	48_F	0.509	0.18
32_T	237_W	0.508	0.18
96_S	149_P	0.507	0.18
304_Y	307_R	0.507	0.18
585_P	591_A	0.506	0.18
59_G	484_S	0.506	0.18
385_I	389_L	0.506	0.18
298_A	573_V	0.506	0.18
60_Y	64_T	0.506	0.18
354_T	518_G	0.506	0.18
258_L	364_H	0.504	0.18
196_E	306_D	0.503	0.18
60_Y	69_S	0.503	0.18
275_D	328_K	0.502	0.18
181_A	431_F	0.502	0.18
505_N	598_I	0.502	0.18
47_K	236_A	0.501	0.18
132_S	560_K	0.501	0.18
283_T	528_L	0.501	0.18
63_D	66_A	0.501	0.18
206_K	209_N	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ulvA	1	0.9444	100	0.433	Contact Map
1lf6A	1	0.9477	100	0.457	Contact Map
2fbaA	1	0.6078	100	0.589	Contact Map
2vn4A	1	0.5605	100	0.616	Contact Map
1gaiA	1	0.5572	100	0.625	Contact Map
1v7wA	2	0.9461	100	0.708	Contact Map
3qryB	1	0.5915	100	0.71	Contact Map
3p2cA	2	0.6242	100	0.716	Contact Map
3qt9A	1	0.6013	100	0.721	Contact Map
2p0vA	2	0.6209	100	0.746	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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