GREMLIN Database
SYT - Threonine--tRNA ligase
UniProt: Q97VW8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 545 (526)
Sequences: 3808 (1818)
Seq/√Len: 79.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
398_D404_K6.2471.00
450_V497_K4.6761.00
456_K503_G4.0171.00
25_K28_A3.9971.00
291_R342_S3.9471.00
341_I345_Q3.4831.00
291_R346_E3.4051.00
148_D241_K3.0741.00
393_K405_R2.9861.00
8_W109_E2.9801.00
190_V237_I2.9521.00
198_T202_K2.9131.00
390_E405_R2.8531.00
458_L468_A2.7441.00
425_L432_L2.6861.00
38_I72_Y2.6851.00
400_D404_K2.6561.00
47_T50_E2.6431.00
122_E126_K2.5981.00
473_A483_N2.5281.00
460_D521_E2.5131.00
151_S164_H2.5081.00
398_D402_I2.4641.00
322_R326_S2.3381.00
121_T124_Q2.3371.00
497_K501_S2.3301.00
87_S91_N2.3041.00
33_E88_T2.2951.00
181_I303_E2.2921.00
329_S332_L2.2821.00
36_F72_Y2.2611.00
444_L477_L2.2521.00
199_D202_K2.2391.00
458_L470_I2.2221.00
55_I60_L2.1941.00
449_E497_K2.1861.00
55_I58_N2.1741.00
120_E124_Q2.1731.00
493_L505_V2.1601.00
439_V469_E2.1431.00
457_V520_F2.1411.00
443_V458_L2.1331.00
181_I184_S2.1321.00
41_K44_T2.1271.00
8_W55_I2.1071.00
345_Q351_F2.1041.00
529_T533_Q2.0941.00
447_T450_V2.0831.00
9_L14_I2.0831.00
338_N342_S2.0691.00
72_Y77_V2.0531.00
295_K346_E2.0401.00
323_P358_G2.0341.00
338_N341_I2.0301.00
181_I185_M2.0181.00
23_G96_E1.9931.00
46_I61_A1.9821.00
326_S330_D1.9781.00
148_D164_H1.9501.00
166_K487_Q1.9431.00
522_K525_E1.9301.00
341_I353_I1.8951.00
56_N60_L1.8911.00
177_F307_K1.8881.00
54_A58_N1.8871.00
196_F233_A1.8841.00
173_E176_A1.8421.00
466_I531_I1.8171.00
41_K45_S1.8041.00
96_E129_L1.7971.00
287_E335_K1.7831.00
299_S347_S1.7821.00
235_I408_M1.7801.00
128_Y132_L1.7641.00
458_L462_R1.7601.00
327_I387_N1.7471.00
466_I527_L1.7471.00
456_K460_D1.7431.00
42_S64_S1.7101.00
455_E458_L1.7101.00
452_E455_E1.7011.00
316_K376_W1.6961.00
354_K357_E1.6711.00
177_F303_E1.6561.00
498_K501_S1.6561.00
142_L146_K1.6401.00
98_L132_L1.6311.00
528_I532_A1.6291.00
525_E529_T1.6291.00
32_G35_D1.6161.00
64_S67_N1.6071.00
446_I477_L1.6041.00
484_A492_I1.5951.00
194_H259_Y1.5931.00
57_E60_L1.5921.00
133_E136_E1.5781.00
166_K469_E1.5711.00
395_E403_K1.5701.00
53_K56_N1.5681.00
170_I421_V1.5661.00
455_E472_Y1.5651.00
24_Y27_V1.5530.99
344_L365_I1.5390.99
526_L530_E1.5330.99
44_T47_T1.5220.99
42_S46_I1.5210.99
434_T527_L1.5180.99
9_L12_A1.5160.99
298_I367_F1.5140.99
464_R528_I1.5140.99
459_N463_K1.5120.99
493_L523_F1.5000.99
263_K266_E1.4910.99
485_Y488_G1.4850.99
102_T110_Q1.4830.99
442_R484_A1.4750.99
431_K488_G1.4670.99
441_V527_L1.4580.99
202_K208_T1.4540.99
294_I365_I1.4490.99
105_P108_N1.4460.99
450_V500_A1.4450.99
368_E376_W1.4430.99
43_D47_T1.4390.99
70_I77_V1.4380.99
453_Y495_V1.4380.99
434_T530_E1.4340.99
63_V66_E1.4300.99
460_D524_L1.4250.99
442_R487_Q1.4240.99
485_Y492_I1.4230.99
54_A57_E1.4150.99
443_V454_A1.4140.99
54_A60_L1.4100.99
461_M524_L1.4080.99
460_D503_G1.4080.99
45_S49_D1.4070.99
198_T223_E1.4030.99
444_L492_I1.3990.99
163_F421_V1.3950.99
209_L325_E1.3860.99
166_K439_V1.3790.99
524_L528_I1.3750.99
240_S243_R1.3750.99
491_Y530_E1.3730.99
494_I506_T1.3670.99
397_I403_K1.3660.99
183_D462_R1.3630.99
176_A180_E1.3580.99
452_E456_K1.3540.99
299_S303_E1.3540.99
15_L19_L1.3510.99
519_K522_K1.3410.98
251_R293_E1.3350.98
53_K58_N1.3310.98
143_I147_L1.3310.98
49_D70_I1.3230.98
509_A512_N1.3060.98
98_L117_V1.2980.98
175_I191_Y1.2950.98
127_D130_S1.2840.98
46_I60_L1.2810.98
178_M304_V1.2800.98
460_D463_K1.2780.98
124_Q127_D1.2730.98
321_T353_I1.2730.98
460_D520_F1.2710.98
42_S45_S1.2700.98
330_D334_E1.2670.98
197_K222_D1.2660.98
171_R191_Y1.2570.98
498_K502_E1.2530.98
460_D464_R1.2510.98
46_I57_E1.2430.97
178_M182_N1.2400.97
276_F416_S1.2360.97
184_S463_K1.2350.97
290_L384_V1.2340.97
185_M303_E1.2340.97
431_K510_R1.2320.97
169_T467_R1.2310.97
133_E137_E1.2280.97
479_K483_N1.2240.97
451_N472_Y1.2210.97
179_R189_E1.2160.97
243_R247_D1.2150.97
16_A20_I1.2130.97
68_N71_V1.2120.97
456_K459_N1.2110.97
7_V14_I1.2060.97
169_T173_E1.2040.97
63_V68_N1.2000.97
40_V70_I1.1990.97
257_H275_G1.1990.97
58_N63_V1.1910.97
58_N62_N1.1890.97
507_V523_F1.1860.97
455_E470_I1.1860.97
101_S110_Q1.1800.96
172_N176_A1.1750.96
321_T341_I1.1740.96
9_L112_V1.1710.96
137_E429_K1.1690.96
42_S65_I1.1680.96
121_T126_K1.1660.96
48_L77_V1.1640.96
448_D451_N1.1630.96
38_I44_T1.1590.96
153_H236_L1.1590.96
123_E127_D1.1570.96
123_E126_K1.1570.96
302_V306_H1.1560.96
441_V466_I1.1560.96
88_T91_N1.1360.96
62_N66_E1.1350.96
173_E467_R1.1350.96
235_I284_F1.1310.96
198_T207_Y1.1240.95
283_I297_L1.1230.95
60_L63_V1.1220.95
151_S240_S1.1200.95
439_V442_R1.1200.95
33_E90_L1.1170.95
148_D151_S1.1160.95
513_I516_R1.1140.95
235_I394_L1.1080.95
59_V62_N1.1070.95
466_I528_I1.1050.95
476_T479_K1.1010.95
454_A470_I1.1000.95
332_L387_N1.0980.95
80_I84_V1.0970.95
243_R250_I1.0970.95
493_L507_V1.0950.95
295_K347_S1.0940.95
182_N255_F1.0920.95
521_E525_E1.0880.94
207_Y225_G1.0860.94
23_G27_V1.0840.94
446_I478_S1.0810.94
185_M300_K1.0790.94
518_V526_L1.0780.94
512_N515_V1.0760.94
326_S334_E1.0730.94
9_L13_V1.0710.94
50_E61_A1.0700.94
342_S346_E1.0700.94
174_L414_Y1.0690.94
33_E89_N1.0660.94
130_S133_E1.0660.94
134_K137_E1.0660.94
288_D399_K1.0630.94
455_E459_N1.0620.94
53_K60_L1.0620.94
194_H257_H1.0570.94
40_V48_L1.0560.94
46_I50_E1.0520.93
12_A18_N1.0490.93
369_I379_L1.0470.93
445_P454_A1.0450.93
35_D73_K1.0450.93
443_V457_V1.0390.93
153_H164_H1.0370.93
190_V234_H1.0310.93
168_Q191_Y1.0280.93
38_I70_I1.0280.93
434_T531_I1.0280.93
334_E338_N1.0280.93
63_V67_N1.0240.92
241_K247_D1.0160.92
218_N221_G1.0110.92
318_Y368_E1.0100.92
171_R175_I1.0070.92
14_I114_I1.0030.92
209_L327_I1.0010.92
339_A384_V0.9960.91
448_D474_G0.9920.91
451_N455_E0.9910.91
445_P450_V0.9900.91
27_V31_L0.9900.91
507_V518_V0.9890.91
54_A59_V0.9890.91
497_K500_A0.9870.91
518_V523_F0.9840.91
18_N21_D0.9810.91
44_T49_D0.9760.91
292_E296_M0.9710.90
441_V493_L0.9700.90
503_G520_F0.9700.90
286_R399_K0.9680.90
273_V276_F0.9670.90
12_A21_D0.9630.90
41_K46_I0.9620.90
178_M255_F0.9610.90
316_K352_G0.9590.90
431_K485_Y0.9580.90
106_N109_E0.9570.90
503_G521_E0.9560.90
11_G109_E0.9540.90
106_N263_K0.9540.90
76_K79_I0.9530.90
14_I20_I0.9510.89
529_T532_A0.9510.89
298_I347_S0.9460.89
185_M299_S0.9450.89
293_E296_M0.9440.89
518_V522_K0.9410.89
442_R469_E0.9380.89
464_R524_L0.9370.89
182_N253_S0.9320.88
174_L308_F0.9290.88
506_T514_E0.9270.88
172_N175_I0.9270.88
32_G75_N0.9240.88
317_P349_L0.9220.88
471_D480_R0.9220.88
514_E517_N0.9160.88
160_L275_G0.9150.88
182_N297_L0.9120.87
443_V495_V0.9090.87
218_N223_E0.9090.87
56_N63_V0.9050.87
306_H311_K0.9040.87
20_I24_Y0.9040.87
55_I109_E0.9030.87
78_S84_V0.9010.87
311_K370_R0.9010.87
190_V252_F0.9010.87
180_E465_R0.8990.87
453_Y500_A0.8990.87
477_L480_R0.8950.86
454_A495_V0.8920.86
25_K32_G0.8910.86
52_K55_I0.8910.86
286_R289_Q0.8910.86
8_W54_A0.8900.86
55_I63_V0.8900.86
143_I146_K0.8890.86
201_W233_A0.8890.86
432_L437_S0.8890.86
130_S137_E0.8820.86
5_K78_S0.8800.85
504_T519_K0.8800.85
32_G88_T0.8790.85
130_S134_K0.8780.85
185_M296_M0.8780.85
156_A162_L0.8770.85
475_E483_N0.8770.85
42_S67_N0.8740.85
445_P470_I0.8730.85
317_P367_F0.8730.85
42_S49_D0.8720.85
177_F181_I0.8700.85
53_K57_E0.8670.85
318_Y354_K0.8660.84
19_L116_G0.8660.84
129_L132_L0.8650.84
254_E277_V0.8620.84
236_L239_K0.8610.84
453_Y457_V0.8600.84
434_T491_Y0.8570.84
54_A109_E0.8500.83
252_F281_G0.8480.83
36_F39_D0.8470.83
62_N65_I0.8450.83
5_K84_V0.8440.83
199_D203_I0.8420.83
388_L391_R0.8340.82
170_I173_E0.8320.82
271_L422_A0.8300.82
98_L129_L0.8290.82
431_K511_G0.8280.82
184_S462_R0.8270.82
486_D510_R0.8230.81
357_E366_D0.8220.81
344_L351_F0.8210.81
173_E531_I0.8210.81
371_D375_R0.8200.81
53_K59_V0.8190.81
28_A32_G0.8180.81
203_I392_F0.8180.81
43_D46_I0.8170.81
512_N516_R0.8140.81
485_Y508_R0.8140.81
86_I94_Y0.8110.80
258_V414_Y0.8090.80
163_F418_D0.8050.80
188_Q252_F0.8050.80
466_I524_L0.8030.80
506_T517_N0.8000.79
37_Y69_Q0.7990.79
441_V468_A0.7980.79
71_V83_K0.7970.79
242_P397_I0.7970.79
443_V470_I0.7960.79
294_I382_I0.7950.79
41_K49_D0.7930.79
131_W373_L0.7920.79
443_V520_F0.7910.79
35_D86_I0.7900.79
184_S303_E0.7900.79
24_Y28_A0.7890.79
48_L72_Y0.7850.78
152_F161_V0.7830.78
24_Y123_E0.7810.78
320_S323_P0.7790.78
182_N414_Y0.7760.77
302_V315_I0.7720.77
469_E489_V0.7690.77
412_A416_S0.7690.77
298_I365_I0.7690.77
106_N110_Q0.7670.77
525_E528_I0.7650.76
160_L196_F0.7630.76
310_F386_F0.7620.76
196_F225_G0.7620.76
72_Y76_K0.7610.76
19_L97_I0.7600.76
292_E295_K0.7590.76
172_N189_E0.7580.76
89_N92_P0.7560.76
278_Q412_A0.7550.75
279_D377_W0.7540.75
322_R330_D0.7540.75
447_T497_K0.7530.75
36_F40_V0.7520.75
144_G150_F0.7510.75
520_F524_L0.7510.75
491_Y523_F0.7500.75
186_G462_R0.7500.75
46_I56_N0.7490.75
147_L487_Q0.7440.74
127_D131_W0.7430.74
319_L344_L0.7420.74
304_V412_A0.7400.74
461_M520_F0.7390.74
242_P403_K0.7390.74
59_V63_V0.7360.74
434_T466_I0.7360.74
321_T358_G0.7310.73
147_L431_K0.7300.73
254_E258_V0.7290.73
215_I261_W0.7280.73
445_P451_N0.7260.73
446_I450_V0.7250.72
445_P495_V0.7240.72
171_R277_V0.7220.72
334_E337_T0.7220.72
321_T354_K0.7200.72
48_L57_E0.7180.72
297_L409_V0.7170.72
42_S66_E0.7160.72
29_V32_G0.7160.72
57_E61_A0.7160.72
84_V115_R0.7160.72
194_H275_G0.7160.72
40_V46_I0.7160.72
251_R296_M0.7150.71
456_K500_A0.7140.71
181_I307_K0.7140.71
60_L64_S0.7140.71
143_I488_G0.7140.71
319_L384_V0.7120.71
209_L387_N0.7110.71
30_G90_L0.7110.71
494_I517_N0.7090.71
46_I49_D0.7070.71
210_Y213_K0.7070.71
258_V297_L0.7070.71
506_T515_V0.7050.70
11_G14_I0.7050.70
161_V275_G0.7050.70
434_T523_F0.7040.70
195_V217_F0.7030.70
181_I300_K0.7030.70
319_L341_I0.7030.70
45_S68_N0.7020.70
39_D67_N0.7020.70
165_P252_F0.7010.70
57_E63_V0.6990.70
97_I114_I0.6980.70
523_F527_L0.6970.69
461_M466_I0.6970.69
60_L68_N0.6960.69
255_F412_A0.6950.69
21_D24_Y0.6940.69
172_N183_D0.6940.69
332_L335_K0.6940.69
81_E87_S0.6930.69
216_V225_G0.6920.69
219_M261_W0.6900.69
212_D325_E0.6890.69
37_Y40_V0.6880.68
515_V518_V0.6870.68
318_Y376_W0.6860.68
457_V461_M0.6840.68
332_L390_E0.6820.68
279_D371_D0.6820.68
52_K57_E0.6810.68
148_D166_K0.6760.67
38_I41_K0.6750.67
353_I357_E0.6730.67
239_K393_K0.6730.67
239_K394_L0.6720.67
38_I49_D0.6720.67
371_D378_Q0.6720.67
201_W323_P0.6720.67
32_G90_L0.6720.67
62_N67_N0.6720.67
5_K80_I0.6700.66
33_E73_K0.6690.66
287_E404_K0.6680.66
175_I417_I0.6670.66
38_I77_V0.6670.66
522_K526_L0.6660.66
362_G386_F0.6650.66
207_Y305_W0.6650.66
339_A343_A0.6620.66
52_K56_N0.6620.66
422_A425_L0.6610.65
172_N179_R0.6600.65
42_S68_N0.6600.65
279_D378_Q0.6600.65
445_P477_L0.6590.65
42_S63_V0.6590.65
105_P109_E0.6580.65
201_W358_G0.6570.65
14_I53_K0.6570.65
35_D90_L0.6570.65
149_L425_L0.6550.65
226_V372_S0.6550.65
387_N390_E0.6540.65
188_Q250_I0.6530.64
136_E142_L0.6520.64
38_I48_L0.6520.64
55_I59_V0.6510.64
189_E305_W0.6510.64
509_A530_E0.6510.64
442_R489_V0.6500.64
149_L432_L0.6500.64
51_V57_E0.6490.64
301_T310_F0.6480.64
485_Y511_G0.6480.64
505_V523_F0.6470.64
134_K138_T0.6460.64
103_H110_Q0.6460.64
320_S354_K0.6450.63
14_I112_V0.6450.63
257_H277_V0.6440.63
485_Y513_I0.6420.63
324_D356_K0.6420.63
79_I84_V0.6420.63
153_H162_L0.6410.63
198_T216_V0.6410.63
61_A64_S0.6400.63
35_D88_T0.6390.63
46_I62_N0.6390.63
175_I255_F0.6370.63
389_P408_M0.6370.63
337_T355_E0.6370.63
117_V120_E0.6370.63
86_I89_N0.6360.62
31_L123_E0.6360.62
178_M414_Y0.6350.62
441_V523_F0.6330.62
153_H156_A0.6320.62
126_K130_S0.6320.62
504_T517_N0.6310.62
354_K368_E0.6300.62
46_I51_V0.6280.61
25_K75_N0.6280.61
473_A476_T0.6270.61
94_Y122_E0.6270.61
81_E84_V0.6270.61
198_T225_G0.6270.61
55_I62_N0.6260.61
258_V277_V0.6260.61
484_A489_V0.6240.61
371_D377_W0.6220.61
12_A15_L0.6210.61
285_L289_Q0.6200.60
308_F420_F0.6190.60
8_W110_Q0.6190.60
305_W380_S0.6190.60
147_L432_L0.6170.60
210_Y366_D0.6170.60
457_V460_D0.6170.60
515_V526_L0.6160.60
447_T476_T0.6150.60
367_F380_S0.6140.60
86_I117_V0.6140.60
30_G94_Y0.6120.59
295_K299_S0.6120.59
303_E307_K0.6090.59
32_G89_N0.6080.59
189_E380_S0.6080.59
52_K58_N0.6080.59
17_I20_I0.6070.59
462_R468_A0.6070.59
297_L382_I0.6060.59
43_D65_I0.6050.59
443_V505_V0.6020.58
69_Q72_Y0.6020.58
301_T367_F0.6020.58
318_Y352_G0.6010.58
34_R88_T0.6000.58
353_I358_G0.5980.58
63_V71_V0.5970.58
304_V413_I0.5960.57
259_Y305_W0.5960.57
160_L194_H0.5960.57
178_M253_S0.5960.57
4_Y58_N0.5960.57
57_E62_N0.5950.57
491_Y509_A0.5940.57
187_Y297_L0.5940.57
70_I76_K0.5930.57
175_I179_R0.5920.57
191_Y257_H0.5920.57
40_V49_D0.5920.57
336_A386_F0.5910.57
176_A183_D0.5900.57
296_M299_S0.5900.57
117_V124_Q0.5900.57
225_G233_A0.5900.57
321_T344_L0.5890.57
442_R477_L0.5880.56
164_H240_S0.5880.56
509_A516_R0.5870.56
168_Q171_R0.5860.56
375_R378_Q0.5860.56
131_W374_G0.5860.56
27_V122_E0.5840.56
30_G35_D0.5820.56
414_Y417_I0.5800.55
259_Y275_G0.5800.55
449_E500_A0.5800.55
29_V73_K0.5790.55
187_Y411_R0.5780.55
27_V30_G0.5770.55
86_I92_P0.5760.55
321_T357_E0.5760.55
195_V224_Y0.5750.55
316_K368_E0.5750.55
485_Y512_N0.5740.55
290_L339_A0.5730.55
335_K339_A0.5730.55
509_A515_V0.5720.54
464_R525_E0.5710.54
237_I386_F0.5710.54
74_G79_I0.5700.54
440_Q467_R0.5690.54
20_I23_G0.5690.54
25_K30_G0.5680.54
195_V233_A0.5670.54
148_D243_R0.5660.54
203_I388_L0.5660.54
441_V495_V0.5650.54
202_K207_Y0.5640.53
54_A62_N0.5630.53
19_L114_I0.5630.53
46_I63_V0.5630.53
97_I116_G0.5620.53
234_H386_F0.5620.53
290_L294_I0.5620.53
323_P379_L0.5620.53
119_F128_Y0.5600.53
40_V44_T0.5600.53
88_T92_P0.5590.53
169_T172_N0.5590.53
78_S115_R0.5590.53
288_D335_K0.5590.53
156_A160_L0.5590.53
169_T183_D0.5580.53
500_A503_G0.5580.53
461_M523_F0.5580.53
279_D423_I0.5570.52
320_S388_L0.5570.52
327_I391_R0.5560.52
60_L65_I0.5560.52
78_S82_D0.5530.52
443_V461_M0.5520.52
258_V271_L0.5520.52
300_K304_V0.5520.52
331_E334_E0.5520.52
437_S489_V0.5510.52
49_D77_V0.5500.52
147_L437_S0.5500.52
255_F417_I0.5500.52
191_Y275_G0.5480.51
182_N258_V0.5480.51
101_S114_I0.5480.51
421_V425_L0.5480.51
156_A236_L0.5470.51
20_I123_E0.5460.51
442_R495_V0.5450.51
207_Y211_R0.5450.51
213_K263_K0.5450.51
189_E255_F0.5450.51
63_V70_I0.5440.51
79_I82_D0.5440.51
207_Y216_V0.5440.51
382_I409_V0.5430.51
73_K88_T0.5420.51
396_Y404_K0.5400.50
234_H284_F0.5390.50
447_T474_G0.5370.50
97_I100_I0.5370.50
26_P97_I0.5360.50
412_A417_I0.5350.50
452_E500_A0.5340.50
215_I220_E0.5340.50
69_Q76_K0.5340.50
182_N186_G0.5330.49
378_Q423_I0.5320.49
95_F118_A0.5320.49
40_V45_S0.5310.49
395_E402_I0.5310.49
502_E517_N0.5300.49
509_A526_L0.5290.49
216_V388_L0.5290.49
30_G95_F0.5280.49
171_R258_V0.5270.49
228_P388_L0.5270.49
196_F217_F0.5260.48
250_I286_R0.5260.48
15_L100_I0.5260.48
237_I252_F0.5250.48
183_D189_E0.5250.48
456_K463_K0.5250.48
258_V417_I0.5250.48
301_T413_I0.5240.48
37_Y79_I0.5230.48
59_V79_I0.5230.48
182_N412_A0.5230.48
106_N266_E0.5230.48
219_M223_E0.5220.48
34_R90_L0.5210.48
70_I74_G0.5200.48
310_F328_G0.5200.48
101_S115_R0.5200.48
179_R255_F0.5190.48
258_V278_Q0.5180.47
278_Q416_S0.5170.47
14_I19_L0.5160.47
4_Y115_R0.5160.47
26_P95_F0.5160.47
326_S358_G0.5160.47
180_E184_S0.5160.47
279_D375_R0.5160.47
492_I511_G0.5160.47
294_I340_L0.5160.47
482_K486_D0.5150.47
268_Y271_L0.5140.47
506_T516_R0.5130.47
41_K47_T0.5130.47
19_L100_I0.5130.47
34_R39_D0.5120.47
225_G305_W0.5120.47
5_K82_D0.5120.47
329_S387_N0.5110.47
96_E133_E0.5100.46
192_T252_F0.5100.46
131_W370_R0.5100.46
8_W11_G0.5090.46
7_V58_N0.5090.46
286_R396_Y0.5090.46
384_V409_V0.5090.46
443_V493_L0.5090.46
46_I52_K0.5090.46
291_R339_A0.5060.46
328_G371_D0.5060.46
488_G511_G0.5060.46
48_L51_V0.5060.46
16_A100_I0.5060.46
202_K223_E0.5050.46
99_N136_E0.5050.46
63_V69_Q0.5040.46
101_S106_N0.5040.46
235_I388_L0.5030.46
377_W380_S0.5030.46
423_I427_H0.5020.45
48_L70_I0.5020.45
305_W369_I0.5020.45
345_Q350_K0.5010.45
284_F394_L0.5000.45
297_L301_T0.5000.45
278_Q371_D0.5000.45
155_E256_G0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qf6A 1 0.9835 100 0.288 Contact Map
1nyrA 2 0.9761 100 0.297 Contact Map
1evlA 2 0.7358 100 0.504 Contact Map
4hwtA 2 0.7339 100 0.507 Contact Map
3uh0A 2 0.7303 100 0.51 Contact Map
3a32A 2 0.7468 100 0.521 Contact Map
2zt5A 2 0.6642 100 0.559 Contact Map
3ialA 2 0.6972 100 0.59 Contact Map
1atiA 2 0.6624 100 0.591 Contact Map
2j3lA 2 0.7431 100 0.592 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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