SYT - SULSO - GREMLIN Contacts

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SYT - Threonine--tRNA ligase

UniProt:	Q97VW8	Sequences: MESYKPVWLKGAVILAINLIDKGYKPVAVGLGERDFYIDVKSDTSITLDEVKKAINENVLANVSIENNQIVYKGNKVSIIEDKVSISTNLNPKYFEILNISTHHPNPNEQYVRIRGVAFETEEQLKDYLSWLEKAEETDHRLIGEKLDLFSFHEEAGSGLVLFHPKGQTIRNELIAFMREINDSMGYQEVYTSHVFKTDIWKISGHYTLYRDKLIVFNMEGDEYGVKPMNCPAHILIYKSKPRTYRDLPIRFSEFGHVYRWEKKGELYGLLRVRGFVQDDGHIFLREDQLREEIKMLISKTVEVWHKFGFKDDDIKPYLSTRPDESIGSDELWEKATNALISALQESGLKFGIKEKEGAFYGPKIDFEIRDSLGRWWQLSTIQVDFNLPERFKLEYIDKDGIKKRPVMVHRAIYGSIDRFVAILLEHFKGKLPTWLSSVQVRVLPITDEVNEYAEKVLNDMRKRRIRAEIDYAGETLSKRIKNAYDQGVPYILIVGKKEASEGTVTVRARGNIEVRNVKFEKFLELLITEIAQRDVEQTTVKALK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	545 (526)
Sequences:	3808 (1818)
Seq/√Len:	79.3

ECOLI - SYT
BACSU - SYT1 SYT2
HALSA - SYT SYP
SULSO - SYT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
398_D	404_K	6.247	1.00
450_V	497_K	4.676	1.00
456_K	503_G	4.017	1.00
25_K	28_A	3.997	1.00
291_R	342_S	3.947	1.00
341_I	345_Q	3.483	1.00
291_R	346_E	3.405	1.00
148_D	241_K	3.074	1.00
393_K	405_R	2.986	1.00
8_W	109_E	2.980	1.00
190_V	237_I	2.952	1.00
198_T	202_K	2.913	1.00
390_E	405_R	2.853	1.00
458_L	468_A	2.744	1.00
425_L	432_L	2.686	1.00
38_I	72_Y	2.685	1.00
400_D	404_K	2.656	1.00
47_T	50_E	2.643	1.00
122_E	126_K	2.598	1.00
473_A	483_N	2.528	1.00
460_D	521_E	2.513	1.00
151_S	164_H	2.508	1.00
398_D	402_I	2.464	1.00
322_R	326_S	2.338	1.00
121_T	124_Q	2.337	1.00
497_K	501_S	2.330	1.00
87_S	91_N	2.304	1.00
33_E	88_T	2.295	1.00
181_I	303_E	2.292	1.00
329_S	332_L	2.282	1.00
36_F	72_Y	2.261	1.00
444_L	477_L	2.252	1.00
199_D	202_K	2.239	1.00
458_L	470_I	2.222	1.00
55_I	60_L	2.194	1.00
449_E	497_K	2.186	1.00
55_I	58_N	2.174	1.00
120_E	124_Q	2.173	1.00
493_L	505_V	2.160	1.00
439_V	469_E	2.143	1.00
457_V	520_F	2.141	1.00
443_V	458_L	2.133	1.00
181_I	184_S	2.132	1.00
41_K	44_T	2.127	1.00
8_W	55_I	2.107	1.00
345_Q	351_F	2.104	1.00
529_T	533_Q	2.094	1.00
447_T	450_V	2.083	1.00
9_L	14_I	2.083	1.00
338_N	342_S	2.069	1.00
72_Y	77_V	2.053	1.00
295_K	346_E	2.040	1.00
323_P	358_G	2.034	1.00
338_N	341_I	2.030	1.00
181_I	185_M	2.018	1.00
23_G	96_E	1.993	1.00
46_I	61_A	1.982	1.00
326_S	330_D	1.978	1.00
148_D	164_H	1.950	1.00
166_K	487_Q	1.943	1.00
522_K	525_E	1.930	1.00
341_I	353_I	1.895	1.00
56_N	60_L	1.891	1.00
177_F	307_K	1.888	1.00
54_A	58_N	1.887	1.00
196_F	233_A	1.884	1.00
173_E	176_A	1.842	1.00
466_I	531_I	1.817	1.00
41_K	45_S	1.804	1.00
96_E	129_L	1.797	1.00
287_E	335_K	1.783	1.00
299_S	347_S	1.782	1.00
235_I	408_M	1.780	1.00
128_Y	132_L	1.764	1.00
458_L	462_R	1.760	1.00
327_I	387_N	1.747	1.00
466_I	527_L	1.747	1.00
456_K	460_D	1.743	1.00
42_S	64_S	1.710	1.00
455_E	458_L	1.710	1.00
452_E	455_E	1.701	1.00
316_K	376_W	1.696	1.00
354_K	357_E	1.671	1.00
177_F	303_E	1.656	1.00
498_K	501_S	1.656	1.00
142_L	146_K	1.640	1.00
98_L	132_L	1.631	1.00
528_I	532_A	1.629	1.00
525_E	529_T	1.629	1.00
32_G	35_D	1.616	1.00
64_S	67_N	1.607	1.00
446_I	477_L	1.604	1.00
484_A	492_I	1.595	1.00
194_H	259_Y	1.593	1.00
57_E	60_L	1.592	1.00
133_E	136_E	1.578	1.00
166_K	469_E	1.571	1.00
395_E	403_K	1.570	1.00
53_K	56_N	1.568	1.00
170_I	421_V	1.566	1.00
455_E	472_Y	1.565	1.00
24_Y	27_V	1.553	0.99
344_L	365_I	1.539	0.99
526_L	530_E	1.533	0.99
44_T	47_T	1.522	0.99
42_S	46_I	1.521	0.99
434_T	527_L	1.518	0.99
9_L	12_A	1.516	0.99
298_I	367_F	1.514	0.99
464_R	528_I	1.514	0.99
459_N	463_K	1.512	0.99
493_L	523_F	1.500	0.99
263_K	266_E	1.491	0.99
485_Y	488_G	1.485	0.99
102_T	110_Q	1.483	0.99
442_R	484_A	1.475	0.99
431_K	488_G	1.467	0.99
441_V	527_L	1.458	0.99
202_K	208_T	1.454	0.99
294_I	365_I	1.449	0.99
105_P	108_N	1.446	0.99
450_V	500_A	1.445	0.99
368_E	376_W	1.443	0.99
43_D	47_T	1.439	0.99
70_I	77_V	1.438	0.99
453_Y	495_V	1.438	0.99
434_T	530_E	1.434	0.99
63_V	66_E	1.430	0.99
460_D	524_L	1.425	0.99
442_R	487_Q	1.424	0.99
485_Y	492_I	1.423	0.99
54_A	57_E	1.415	0.99
443_V	454_A	1.414	0.99
54_A	60_L	1.410	0.99
461_M	524_L	1.408	0.99
460_D	503_G	1.408	0.99
45_S	49_D	1.407	0.99
198_T	223_E	1.403	0.99
444_L	492_I	1.399	0.99
163_F	421_V	1.395	0.99
209_L	325_E	1.386	0.99
166_K	439_V	1.379	0.99
524_L	528_I	1.375	0.99
240_S	243_R	1.375	0.99
491_Y	530_E	1.373	0.99
494_I	506_T	1.367	0.99
397_I	403_K	1.366	0.99
183_D	462_R	1.363	0.99
176_A	180_E	1.358	0.99
452_E	456_K	1.354	0.99
299_S	303_E	1.354	0.99
15_L	19_L	1.351	0.99
519_K	522_K	1.341	0.98
251_R	293_E	1.335	0.98
53_K	58_N	1.331	0.98
143_I	147_L	1.331	0.98
49_D	70_I	1.323	0.98
509_A	512_N	1.306	0.98
98_L	117_V	1.298	0.98
175_I	191_Y	1.295	0.98
127_D	130_S	1.284	0.98
46_I	60_L	1.281	0.98
178_M	304_V	1.280	0.98
460_D	463_K	1.278	0.98
124_Q	127_D	1.273	0.98
321_T	353_I	1.273	0.98
460_D	520_F	1.271	0.98
42_S	45_S	1.270	0.98
330_D	334_E	1.267	0.98
197_K	222_D	1.266	0.98
171_R	191_Y	1.257	0.98
498_K	502_E	1.253	0.98
460_D	464_R	1.251	0.98
46_I	57_E	1.243	0.97
178_M	182_N	1.240	0.97
276_F	416_S	1.236	0.97
184_S	463_K	1.235	0.97
290_L	384_V	1.234	0.97
185_M	303_E	1.234	0.97
431_K	510_R	1.232	0.97
169_T	467_R	1.231	0.97
133_E	137_E	1.228	0.97
479_K	483_N	1.224	0.97
451_N	472_Y	1.221	0.97
179_R	189_E	1.216	0.97
243_R	247_D	1.215	0.97
16_A	20_I	1.213	0.97
68_N	71_V	1.212	0.97
456_K	459_N	1.211	0.97
7_V	14_I	1.206	0.97
169_T	173_E	1.204	0.97
63_V	68_N	1.200	0.97
40_V	70_I	1.199	0.97
257_H	275_G	1.199	0.97
58_N	63_V	1.191	0.97
58_N	62_N	1.189	0.97
507_V	523_F	1.186	0.97
455_E	470_I	1.186	0.97
101_S	110_Q	1.180	0.96
172_N	176_A	1.175	0.96
321_T	341_I	1.174	0.96
9_L	112_V	1.171	0.96
137_E	429_K	1.169	0.96
42_S	65_I	1.168	0.96
121_T	126_K	1.166	0.96
48_L	77_V	1.164	0.96
448_D	451_N	1.163	0.96
38_I	44_T	1.159	0.96
153_H	236_L	1.159	0.96
123_E	127_D	1.157	0.96
123_E	126_K	1.157	0.96
302_V	306_H	1.156	0.96
441_V	466_I	1.156	0.96
88_T	91_N	1.136	0.96
62_N	66_E	1.135	0.96
173_E	467_R	1.135	0.96
235_I	284_F	1.131	0.96
198_T	207_Y	1.124	0.95
283_I	297_L	1.123	0.95
60_L	63_V	1.122	0.95
151_S	240_S	1.120	0.95
439_V	442_R	1.120	0.95
33_E	90_L	1.117	0.95
148_D	151_S	1.116	0.95
513_I	516_R	1.114	0.95
235_I	394_L	1.108	0.95
59_V	62_N	1.107	0.95
466_I	528_I	1.105	0.95
476_T	479_K	1.101	0.95
454_A	470_I	1.100	0.95
332_L	387_N	1.098	0.95
80_I	84_V	1.097	0.95
243_R	250_I	1.097	0.95
493_L	507_V	1.095	0.95
295_K	347_S	1.094	0.95
182_N	255_F	1.092	0.95
521_E	525_E	1.088	0.94
207_Y	225_G	1.086	0.94
23_G	27_V	1.084	0.94
446_I	478_S	1.081	0.94
185_M	300_K	1.079	0.94
518_V	526_L	1.078	0.94
512_N	515_V	1.076	0.94
326_S	334_E	1.073	0.94
9_L	13_V	1.071	0.94
50_E	61_A	1.070	0.94
342_S	346_E	1.070	0.94
174_L	414_Y	1.069	0.94
33_E	89_N	1.066	0.94
130_S	133_E	1.066	0.94
134_K	137_E	1.066	0.94
288_D	399_K	1.063	0.94
455_E	459_N	1.062	0.94
53_K	60_L	1.062	0.94
194_H	257_H	1.057	0.94
40_V	48_L	1.056	0.94
46_I	50_E	1.052	0.93
12_A	18_N	1.049	0.93
369_I	379_L	1.047	0.93
445_P	454_A	1.045	0.93
35_D	73_K	1.045	0.93
443_V	457_V	1.039	0.93
153_H	164_H	1.037	0.93
190_V	234_H	1.031	0.93
168_Q	191_Y	1.028	0.93
38_I	70_I	1.028	0.93
434_T	531_I	1.028	0.93
334_E	338_N	1.028	0.93
63_V	67_N	1.024	0.92
241_K	247_D	1.016	0.92
218_N	221_G	1.011	0.92
318_Y	368_E	1.010	0.92
171_R	175_I	1.007	0.92
14_I	114_I	1.003	0.92
209_L	327_I	1.001	0.92
339_A	384_V	0.996	0.91
448_D	474_G	0.992	0.91
451_N	455_E	0.991	0.91
445_P	450_V	0.990	0.91
27_V	31_L	0.990	0.91
507_V	518_V	0.989	0.91
54_A	59_V	0.989	0.91
497_K	500_A	0.987	0.91
518_V	523_F	0.984	0.91
18_N	21_D	0.981	0.91
44_T	49_D	0.976	0.91
292_E	296_M	0.971	0.90
441_V	493_L	0.970	0.90
503_G	520_F	0.970	0.90
286_R	399_K	0.968	0.90
273_V	276_F	0.967	0.90
12_A	21_D	0.963	0.90
41_K	46_I	0.962	0.90
178_M	255_F	0.961	0.90
316_K	352_G	0.959	0.90
431_K	485_Y	0.958	0.90
106_N	109_E	0.957	0.90
503_G	521_E	0.956	0.90
11_G	109_E	0.954	0.90
106_N	263_K	0.954	0.90
76_K	79_I	0.953	0.90
14_I	20_I	0.951	0.89
529_T	532_A	0.951	0.89
298_I	347_S	0.946	0.89
185_M	299_S	0.945	0.89
293_E	296_M	0.944	0.89
518_V	522_K	0.941	0.89
442_R	469_E	0.938	0.89
464_R	524_L	0.937	0.89
182_N	253_S	0.932	0.88
174_L	308_F	0.929	0.88
506_T	514_E	0.927	0.88
172_N	175_I	0.927	0.88
32_G	75_N	0.924	0.88
317_P	349_L	0.922	0.88
471_D	480_R	0.922	0.88
514_E	517_N	0.916	0.88
160_L	275_G	0.915	0.88
182_N	297_L	0.912	0.87
443_V	495_V	0.909	0.87
218_N	223_E	0.909	0.87
56_N	63_V	0.905	0.87
306_H	311_K	0.904	0.87
20_I	24_Y	0.904	0.87
55_I	109_E	0.903	0.87
78_S	84_V	0.901	0.87
311_K	370_R	0.901	0.87
190_V	252_F	0.901	0.87
180_E	465_R	0.899	0.87
453_Y	500_A	0.899	0.87
477_L	480_R	0.895	0.86
454_A	495_V	0.892	0.86
25_K	32_G	0.891	0.86
52_K	55_I	0.891	0.86
286_R	289_Q	0.891	0.86
8_W	54_A	0.890	0.86
55_I	63_V	0.890	0.86
143_I	146_K	0.889	0.86
201_W	233_A	0.889	0.86
432_L	437_S	0.889	0.86
130_S	137_E	0.882	0.86
5_K	78_S	0.880	0.85
504_T	519_K	0.880	0.85
32_G	88_T	0.879	0.85
130_S	134_K	0.878	0.85
185_M	296_M	0.878	0.85
156_A	162_L	0.877	0.85
475_E	483_N	0.877	0.85
42_S	67_N	0.874	0.85
445_P	470_I	0.873	0.85
317_P	367_F	0.873	0.85
42_S	49_D	0.872	0.85
177_F	181_I	0.870	0.85
53_K	57_E	0.867	0.85
318_Y	354_K	0.866	0.84
19_L	116_G	0.866	0.84
129_L	132_L	0.865	0.84
254_E	277_V	0.862	0.84
236_L	239_K	0.861	0.84
453_Y	457_V	0.860	0.84
434_T	491_Y	0.857	0.84
54_A	109_E	0.850	0.83
252_F	281_G	0.848	0.83
36_F	39_D	0.847	0.83
62_N	65_I	0.845	0.83
5_K	84_V	0.844	0.83
199_D	203_I	0.842	0.83
388_L	391_R	0.834	0.82
170_I	173_E	0.832	0.82
271_L	422_A	0.830	0.82
98_L	129_L	0.829	0.82
431_K	511_G	0.828	0.82
184_S	462_R	0.827	0.82
486_D	510_R	0.823	0.81
357_E	366_D	0.822	0.81
344_L	351_F	0.821	0.81
173_E	531_I	0.821	0.81
371_D	375_R	0.820	0.81
53_K	59_V	0.819	0.81
28_A	32_G	0.818	0.81
203_I	392_F	0.818	0.81
43_D	46_I	0.817	0.81
512_N	516_R	0.814	0.81
485_Y	508_R	0.814	0.81
86_I	94_Y	0.811	0.80
258_V	414_Y	0.809	0.80
163_F	418_D	0.805	0.80
188_Q	252_F	0.805	0.80
466_I	524_L	0.803	0.80
506_T	517_N	0.800	0.79
37_Y	69_Q	0.799	0.79
441_V	468_A	0.798	0.79
71_V	83_K	0.797	0.79
242_P	397_I	0.797	0.79
443_V	470_I	0.796	0.79
294_I	382_I	0.795	0.79
41_K	49_D	0.793	0.79
131_W	373_L	0.792	0.79
443_V	520_F	0.791	0.79
35_D	86_I	0.790	0.79
184_S	303_E	0.790	0.79
24_Y	28_A	0.789	0.79
48_L	72_Y	0.785	0.78
152_F	161_V	0.783	0.78
24_Y	123_E	0.781	0.78
320_S	323_P	0.779	0.78
182_N	414_Y	0.776	0.77
302_V	315_I	0.772	0.77
469_E	489_V	0.769	0.77
412_A	416_S	0.769	0.77
298_I	365_I	0.769	0.77
106_N	110_Q	0.767	0.77
525_E	528_I	0.765	0.76
160_L	196_F	0.763	0.76
310_F	386_F	0.762	0.76
196_F	225_G	0.762	0.76
72_Y	76_K	0.761	0.76
19_L	97_I	0.760	0.76
292_E	295_K	0.759	0.76
172_N	189_E	0.758	0.76
89_N	92_P	0.756	0.76
278_Q	412_A	0.755	0.75
279_D	377_W	0.754	0.75
322_R	330_D	0.754	0.75
447_T	497_K	0.753	0.75
36_F	40_V	0.752	0.75
144_G	150_F	0.751	0.75
520_F	524_L	0.751	0.75
491_Y	523_F	0.750	0.75
186_G	462_R	0.750	0.75
46_I	56_N	0.749	0.75
147_L	487_Q	0.744	0.74
127_D	131_W	0.743	0.74
319_L	344_L	0.742	0.74
304_V	412_A	0.740	0.74
461_M	520_F	0.739	0.74
242_P	403_K	0.739	0.74
59_V	63_V	0.736	0.74
434_T	466_I	0.736	0.74
321_T	358_G	0.731	0.73
147_L	431_K	0.730	0.73
254_E	258_V	0.729	0.73
215_I	261_W	0.728	0.73
445_P	451_N	0.726	0.73
446_I	450_V	0.725	0.72
445_P	495_V	0.724	0.72
171_R	277_V	0.722	0.72
334_E	337_T	0.722	0.72
321_T	354_K	0.720	0.72
48_L	57_E	0.718	0.72
297_L	409_V	0.717	0.72
42_S	66_E	0.716	0.72
29_V	32_G	0.716	0.72
57_E	61_A	0.716	0.72
84_V	115_R	0.716	0.72
194_H	275_G	0.716	0.72
40_V	46_I	0.716	0.72
251_R	296_M	0.715	0.71
456_K	500_A	0.714	0.71
181_I	307_K	0.714	0.71
60_L	64_S	0.714	0.71
143_I	488_G	0.714	0.71
319_L	384_V	0.712	0.71
209_L	387_N	0.711	0.71
30_G	90_L	0.711	0.71
494_I	517_N	0.709	0.71
46_I	49_D	0.707	0.71
210_Y	213_K	0.707	0.71
258_V	297_L	0.707	0.71
506_T	515_V	0.705	0.70
11_G	14_I	0.705	0.70
161_V	275_G	0.705	0.70
434_T	523_F	0.704	0.70
195_V	217_F	0.703	0.70
181_I	300_K	0.703	0.70
319_L	341_I	0.703	0.70
45_S	68_N	0.702	0.70
39_D	67_N	0.702	0.70
165_P	252_F	0.701	0.70
57_E	63_V	0.699	0.70
97_I	114_I	0.698	0.70
523_F	527_L	0.697	0.69
461_M	466_I	0.697	0.69
60_L	68_N	0.696	0.69
255_F	412_A	0.695	0.69
21_D	24_Y	0.694	0.69
172_N	183_D	0.694	0.69
332_L	335_K	0.694	0.69
81_E	87_S	0.693	0.69
216_V	225_G	0.692	0.69
219_M	261_W	0.690	0.69
212_D	325_E	0.689	0.69
37_Y	40_V	0.688	0.68
515_V	518_V	0.687	0.68
318_Y	376_W	0.686	0.68
457_V	461_M	0.684	0.68
332_L	390_E	0.682	0.68
279_D	371_D	0.682	0.68
52_K	57_E	0.681	0.68
148_D	166_K	0.676	0.67
38_I	41_K	0.675	0.67
353_I	357_E	0.673	0.67
239_K	393_K	0.673	0.67
239_K	394_L	0.672	0.67
38_I	49_D	0.672	0.67
371_D	378_Q	0.672	0.67
201_W	323_P	0.672	0.67
32_G	90_L	0.672	0.67
62_N	67_N	0.672	0.67
5_K	80_I	0.670	0.66
33_E	73_K	0.669	0.66
287_E	404_K	0.668	0.66
175_I	417_I	0.667	0.66
38_I	77_V	0.667	0.66
522_K	526_L	0.666	0.66
362_G	386_F	0.665	0.66
207_Y	305_W	0.665	0.66
339_A	343_A	0.662	0.66
52_K	56_N	0.662	0.66
422_A	425_L	0.661	0.65
172_N	179_R	0.660	0.65
42_S	68_N	0.660	0.65
279_D	378_Q	0.660	0.65
445_P	477_L	0.659	0.65
42_S	63_V	0.659	0.65
105_P	109_E	0.658	0.65
201_W	358_G	0.657	0.65
14_I	53_K	0.657	0.65
35_D	90_L	0.657	0.65
149_L	425_L	0.655	0.65
226_V	372_S	0.655	0.65
387_N	390_E	0.654	0.65
188_Q	250_I	0.653	0.64
136_E	142_L	0.652	0.64
38_I	48_L	0.652	0.64
55_I	59_V	0.651	0.64
189_E	305_W	0.651	0.64
509_A	530_E	0.651	0.64
442_R	489_V	0.650	0.64
149_L	432_L	0.650	0.64
51_V	57_E	0.649	0.64
301_T	310_F	0.648	0.64
485_Y	511_G	0.648	0.64
505_V	523_F	0.647	0.64
134_K	138_T	0.646	0.64
103_H	110_Q	0.646	0.64
320_S	354_K	0.645	0.63
14_I	112_V	0.645	0.63
257_H	277_V	0.644	0.63
485_Y	513_I	0.642	0.63
324_D	356_K	0.642	0.63
79_I	84_V	0.642	0.63
153_H	162_L	0.641	0.63
198_T	216_V	0.641	0.63
61_A	64_S	0.640	0.63
35_D	88_T	0.639	0.63
46_I	62_N	0.639	0.63
175_I	255_F	0.637	0.63
389_P	408_M	0.637	0.63
337_T	355_E	0.637	0.63
117_V	120_E	0.637	0.63
86_I	89_N	0.636	0.62
31_L	123_E	0.636	0.62
178_M	414_Y	0.635	0.62
441_V	523_F	0.633	0.62
153_H	156_A	0.632	0.62
126_K	130_S	0.632	0.62
504_T	517_N	0.631	0.62
354_K	368_E	0.630	0.62
46_I	51_V	0.628	0.61
25_K	75_N	0.628	0.61
473_A	476_T	0.627	0.61
94_Y	122_E	0.627	0.61
81_E	84_V	0.627	0.61
198_T	225_G	0.627	0.61
55_I	62_N	0.626	0.61
258_V	277_V	0.626	0.61
484_A	489_V	0.624	0.61
371_D	377_W	0.622	0.61
12_A	15_L	0.621	0.61
285_L	289_Q	0.620	0.60
308_F	420_F	0.619	0.60
8_W	110_Q	0.619	0.60
305_W	380_S	0.619	0.60
147_L	432_L	0.617	0.60
210_Y	366_D	0.617	0.60
457_V	460_D	0.617	0.60
515_V	526_L	0.616	0.60
447_T	476_T	0.615	0.60
367_F	380_S	0.614	0.60
86_I	117_V	0.614	0.60
30_G	94_Y	0.612	0.59
295_K	299_S	0.612	0.59
303_E	307_K	0.609	0.59
32_G	89_N	0.608	0.59
189_E	380_S	0.608	0.59
52_K	58_N	0.608	0.59
17_I	20_I	0.607	0.59
462_R	468_A	0.607	0.59
297_L	382_I	0.606	0.59
43_D	65_I	0.605	0.59
443_V	505_V	0.602	0.58
69_Q	72_Y	0.602	0.58
301_T	367_F	0.602	0.58
318_Y	352_G	0.601	0.58
34_R	88_T	0.600	0.58
353_I	358_G	0.598	0.58
63_V	71_V	0.597	0.58
304_V	413_I	0.596	0.57
259_Y	305_W	0.596	0.57
160_L	194_H	0.596	0.57
178_M	253_S	0.596	0.57
4_Y	58_N	0.596	0.57
57_E	62_N	0.595	0.57
491_Y	509_A	0.594	0.57
187_Y	297_L	0.594	0.57
70_I	76_K	0.593	0.57
175_I	179_R	0.592	0.57
191_Y	257_H	0.592	0.57
40_V	49_D	0.592	0.57
336_A	386_F	0.591	0.57
176_A	183_D	0.590	0.57
296_M	299_S	0.590	0.57
117_V	124_Q	0.590	0.57
225_G	233_A	0.590	0.57
321_T	344_L	0.589	0.57
442_R	477_L	0.588	0.56
164_H	240_S	0.588	0.56
509_A	516_R	0.587	0.56
168_Q	171_R	0.586	0.56
375_R	378_Q	0.586	0.56
131_W	374_G	0.586	0.56
27_V	122_E	0.584	0.56
30_G	35_D	0.582	0.56
414_Y	417_I	0.580	0.55
259_Y	275_G	0.580	0.55
449_E	500_A	0.580	0.55
29_V	73_K	0.579	0.55
187_Y	411_R	0.578	0.55
27_V	30_G	0.577	0.55
86_I	92_P	0.576	0.55
321_T	357_E	0.576	0.55
195_V	224_Y	0.575	0.55
316_K	368_E	0.575	0.55
485_Y	512_N	0.574	0.55
290_L	339_A	0.573	0.55
335_K	339_A	0.573	0.55
509_A	515_V	0.572	0.54
464_R	525_E	0.571	0.54
237_I	386_F	0.571	0.54
74_G	79_I	0.570	0.54
440_Q	467_R	0.569	0.54
20_I	23_G	0.569	0.54
25_K	30_G	0.568	0.54
195_V	233_A	0.567	0.54
148_D	243_R	0.566	0.54
203_I	388_L	0.566	0.54
441_V	495_V	0.565	0.54
202_K	207_Y	0.564	0.53
54_A	62_N	0.563	0.53
19_L	114_I	0.563	0.53
46_I	63_V	0.563	0.53
97_I	116_G	0.562	0.53
234_H	386_F	0.562	0.53
290_L	294_I	0.562	0.53
323_P	379_L	0.562	0.53
119_F	128_Y	0.560	0.53
40_V	44_T	0.560	0.53
88_T	92_P	0.559	0.53
169_T	172_N	0.559	0.53
78_S	115_R	0.559	0.53
288_D	335_K	0.559	0.53
156_A	160_L	0.559	0.53
169_T	183_D	0.558	0.53
500_A	503_G	0.558	0.53
461_M	523_F	0.558	0.53
279_D	423_I	0.557	0.52
320_S	388_L	0.557	0.52
327_I	391_R	0.556	0.52
60_L	65_I	0.556	0.52
78_S	82_D	0.553	0.52
443_V	461_M	0.552	0.52
258_V	271_L	0.552	0.52
300_K	304_V	0.552	0.52
331_E	334_E	0.552	0.52
437_S	489_V	0.551	0.52
49_D	77_V	0.550	0.52
147_L	437_S	0.550	0.52
255_F	417_I	0.550	0.52
191_Y	275_G	0.548	0.51
182_N	258_V	0.548	0.51
101_S	114_I	0.548	0.51
421_V	425_L	0.548	0.51
156_A	236_L	0.547	0.51
20_I	123_E	0.546	0.51
442_R	495_V	0.545	0.51
207_Y	211_R	0.545	0.51
213_K	263_K	0.545	0.51
189_E	255_F	0.545	0.51
63_V	70_I	0.544	0.51
79_I	82_D	0.544	0.51
207_Y	216_V	0.544	0.51
382_I	409_V	0.543	0.51
73_K	88_T	0.542	0.51
396_Y	404_K	0.540	0.50
234_H	284_F	0.539	0.50
447_T	474_G	0.537	0.50
97_I	100_I	0.537	0.50
26_P	97_I	0.536	0.50
412_A	417_I	0.535	0.50
452_E	500_A	0.534	0.50
215_I	220_E	0.534	0.50
69_Q	76_K	0.534	0.50
182_N	186_G	0.533	0.49
378_Q	423_I	0.532	0.49
95_F	118_A	0.532	0.49
40_V	45_S	0.531	0.49
395_E	402_I	0.531	0.49
502_E	517_N	0.530	0.49
509_A	526_L	0.529	0.49
216_V	388_L	0.529	0.49
30_G	95_F	0.528	0.49
171_R	258_V	0.527	0.49
228_P	388_L	0.527	0.49
196_F	217_F	0.526	0.48
250_I	286_R	0.526	0.48
15_L	100_I	0.526	0.48
237_I	252_F	0.525	0.48
183_D	189_E	0.525	0.48
456_K	463_K	0.525	0.48
258_V	417_I	0.525	0.48
301_T	413_I	0.524	0.48
37_Y	79_I	0.523	0.48
59_V	79_I	0.523	0.48
182_N	412_A	0.523	0.48
106_N	266_E	0.523	0.48
219_M	223_E	0.522	0.48
34_R	90_L	0.521	0.48
70_I	74_G	0.520	0.48
310_F	328_G	0.520	0.48
101_S	115_R	0.520	0.48
179_R	255_F	0.519	0.48
258_V	278_Q	0.518	0.47
278_Q	416_S	0.517	0.47
14_I	19_L	0.516	0.47
4_Y	115_R	0.516	0.47
26_P	95_F	0.516	0.47
326_S	358_G	0.516	0.47
180_E	184_S	0.516	0.47
279_D	375_R	0.516	0.47
492_I	511_G	0.516	0.47
294_I	340_L	0.516	0.47
482_K	486_D	0.515	0.47
268_Y	271_L	0.514	0.47
506_T	516_R	0.513	0.47
41_K	47_T	0.513	0.47
19_L	100_I	0.513	0.47
34_R	39_D	0.512	0.47
225_G	305_W	0.512	0.47
5_K	82_D	0.512	0.47
329_S	387_N	0.511	0.47
96_E	133_E	0.510	0.46
192_T	252_F	0.510	0.46
131_W	370_R	0.510	0.46
8_W	11_G	0.509	0.46
7_V	58_N	0.509	0.46
286_R	396_Y	0.509	0.46
384_V	409_V	0.509	0.46
443_V	493_L	0.509	0.46
46_I	52_K	0.509	0.46
291_R	339_A	0.506	0.46
328_G	371_D	0.506	0.46
488_G	511_G	0.506	0.46
48_L	51_V	0.506	0.46
16_A	100_I	0.506	0.46
202_K	223_E	0.505	0.46
99_N	136_E	0.505	0.46
63_V	69_Q	0.504	0.46
101_S	106_N	0.504	0.46
235_I	388_L	0.503	0.46
377_W	380_S	0.503	0.46
423_I	427_H	0.502	0.45
48_L	70_I	0.502	0.45
305_W	369_I	0.502	0.45
345_Q	350_K	0.501	0.45
284_F	394_L	0.500	0.45
297_L	301_T	0.500	0.45
278_Q	371_D	0.500	0.45
155_E	256_G	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1qf6A	1	0.9835	100	0.288	Contact Map
1nyrA	2	0.9761	100	0.297	Contact Map
1evlA	2	0.7358	100	0.504	Contact Map
4hwtA	2	0.7339	100	0.507	Contact Map
3uh0A	2	0.7303	100	0.51	Contact Map
3a32A	2	0.7468	100	0.521	Contact Map
2zt5A	2	0.6642	100	0.559	Contact Map
3ialA	2	0.6972	100	0.59	Contact Map
1atiA	2	0.6624	100	0.591	Contact Map
2j3lA	2	0.7431	100	0.592	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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