Q97VU5 - SULSO - GREMLIN Contacts

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Q97VU5 - 3-hydroxyacyl-CoA dehydrogenase/enoyl CoA hydratase

UniProt:	Q97VU5	Sequences: MKVEDIKKILVVGAGTMGHGIAEIAAISGYKVYLSDISQDILNNALERIRWSLSKLQERGQIKESVDTIMSRITTIVGLDKTVSDADFSIEASTERMDIKRQVFSKLDELLPPHAILATNTSSLPISKIAEATKRQDKVVGMHFFNPPVLMQLVEVMKGDKTSDETAKITYDLAKKFGKQPIMINKDVPGYVVNRILGQINIASCILVEKKVADYREVDAVARYKLGFPMGVFELIDYTGVDVAYYVSKSREELGIRDDIPICSLIEQKFKNNELGVKTGKGFYTYPAPGKYVKPELPKELADKLNPALILAGGVNEATRLLREGIASRDDIDLGVRLGLGLPKGIFQYADELGVDTVLKALEDLKALSGYNTFNPDPMITQMIRENKLGIKTGSGFYQYGKVEEKKMNTLIIRIEPPLAWIILNRPERLNALNPELVSELDKSLDELESRSDVRVVIITGNGRAFSAGADVSSFITLRPIDVIRLRTLRNVVNKIALYTKPIIAGINGFALGGGLELAMACDIRIASEVAQLGQPEINIGIIPGAGGTQRLPRLVGKGKAKLMIYTGDMVSAEDAYKMGLVDLVVPSNRFEEEVRRVALKIAEKSPISLLAAKLAIELGYESNIWTGQTLESTLFGLLFTTKDVEEGVKAFLEKRKPQFKGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	663 (645)
Sequences:	889 (594)
Seq/√Len:	23.4

BACSU - FADN
HALSA - Q9HQ61
SULSO - Q97VU5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
607_P	610_L	5.445	1.00
611_L	614_K	5.208	1.00
611_L	615_L	4.970	1.00
505_A	522_C	4.315	1.00
136_Q	161_K	4.029	1.00
565_I	569_D	3.806	1.00
468_A	510_F	3.797	1.00
612_A	615_L	3.764	1.00
626_W	630_T	3.677	1.00
565_I	568_G	3.633	1.00
422_I	441_L	3.489	1.00
606_S	610_L	3.445	1.00
456_V	599_A	3.438	1.00
446_D	495_K	3.390	1.00
93_S	99_I	3.374	1.00
89_S	111_L	3.367	1.00
487_R	491_N	3.353	1.00
137_D	163_S	3.314	1.00
564_M	567_T	3.306	1.00
275_L	279_T	3.240	1.00
564_M	569_D	3.188	1.00
411_L	425_N	3.076	1.00
566_Y	569_D	3.044	1.00
563_L	568_G	3.004	1.00
563_L	567_T	2.995	1.00
78_G	82_T	2.984	1.00
564_M	568_G	2.968	1.00
294_K	297_L	2.965	1.00
419_L	599_A	2.894	0.99
526_I	585_V	2.884	0.99
12_V	75_T	2.824	0.99
12_V	107_L	2.768	0.99
562_K	565_I	2.750	0.99
328_S	331_D	2.719	0.99
563_L	566_Y	2.702	0.99
141_G	157_M	2.684	0.99
563_L	569_D	2.675	0.99
308_A	361_A	2.658	0.99
561_A	565_I	2.564	0.99
585_V	594_E	2.554	0.99
524_I	598_V	2.524	0.99
111_L	138_K	2.463	0.98
562_K	567_T	2.422	0.98
651_A	655_K	2.421	0.98
420_A	454_V	2.402	0.98
557_G	561_A	2.371	0.98
268_Q	272_N	2.338	0.98
475_F	640_F	2.333	0.98
447_E	453_D	2.289	0.97
9_I	25_A	2.275	0.97
505_A	519_A	2.251	0.97
293_V	297_L	2.250	0.97
526_I	594_E	2.246	0.97
561_A	567_T	2.225	0.97
93_S	103_V	2.211	0.97
562_K	568_G	2.181	0.96
52_S	58_E	2.178	0.96
55_K	58_E	2.160	0.96
58_E	61_Q	2.122	0.96
53_L	58_E	2.121	0.96
562_K	569_D	2.119	0.96
46_L	58_E	2.111	0.95
88_F	118_A	2.104	0.95
46_L	50_R	2.099	0.95
365_L	369_S	2.059	0.95
52_S	59_R	2.058	0.95
67_D	70_M	2.026	0.94
28_S	586_V	2.019	0.94
231_G	235_L	2.004	0.94
44_N	47_E	1.996	0.94
291_K	294_K	1.990	0.94
606_S	609_S	1.972	0.93
33_Y	82_T	1.956	0.93
172_D	176_K	1.946	0.93
82_T	85_D	1.942	0.93
114_H	138_K	1.940	0.93
222_A	232_V	1.911	0.92
213_A	302_A	1.909	0.92
337_R	348_Q	1.875	0.92
281_K	285_T	1.870	0.91
638_L	641_T	1.868	0.91
50_R	58_E	1.865	0.91
561_A	569_D	1.852	0.91
180_Q	338_L	1.818	0.90
365_L	373_T	1.805	0.90
10_L	86_A	1.801	0.90
561_A	568_G	1.796	0.90
449_E	500_T	1.792	0.90
249_K	253_E	1.791	0.90
108_D	134_K	1.780	0.89
221_V	306_N	1.771	0.89
299_K	304_K	1.771	0.89
562_K	566_Y	1.770	0.89
79_L	106_K	1.767	0.89
103_V	106_K	1.763	0.89
51_W	58_E	1.761	0.89
432_A	468_A	1.761	0.89
207_L	210_K	1.758	0.89
112_P	115_A	1.750	0.88
489_L	546_A	1.737	0.88
360_K	364_D	1.730	0.88
558_K	562_K	1.728	0.88
366_K	369_S	1.723	0.88
407_K	412_I	1.722	0.88
365_L	370_G	1.717	0.87
405_E	443_K	1.703	0.87
561_A	564_M	1.693	0.87
236_I	244_A	1.690	0.87
356_D	360_K	1.681	0.86
638_L	642_T	1.679	0.86
409_N	436_E	1.671	0.86
104_F	129_I	1.659	0.85
448_L	501_K	1.655	0.85
35_S	73_I	1.652	0.85
75_T	107_L	1.649	0.85
102_Q	105_S	1.642	0.85
55_K	59_R	1.641	0.85
46_L	49_I	1.632	0.85
31_K	69_I	1.613	0.84
308_A	312_A	1.608	0.84
118_A	140_V	1.601	0.83
49_I	55_K	1.600	0.83
323_R	332_I	1.600	0.83
128_K	131_E	1.592	0.83
634_T	638_L	1.580	0.83
387_N	394_G	1.580	0.83
497_A	551_R	1.578	0.82
217_E	302_A	1.575	0.82
105_S	133_T	1.570	0.82
404_E	412_I	1.561	0.82
61_Q	70_M	1.560	0.82
365_L	374_F	1.558	0.82
465_A	468_A	1.552	0.81
291_K	297_L	1.534	0.81
108_D	133_T	1.528	0.80
8_K	85_D	1.527	0.80
407_K	414_R	1.524	0.80
496_I	523_D	1.516	0.80
213_A	306_N	1.511	0.80
459_I	496_I	1.511	0.80
528_S	588_S	1.498	0.79
151_M	341_G	1.492	0.79
389_L	394_G	1.489	0.79
127_S	160_D	1.480	0.78
377_D	392_K	1.473	0.78
75_T	79_L	1.472	0.78
418_P	603_A	1.469	0.78
117_L	133_T	1.468	0.78
404_E	420_A	1.457	0.77
274_E	281_K	1.448	0.77
288_A	291_K	1.441	0.76
111_L	115_A	1.437	0.76
369_S	373_T	1.430	0.76
175_K	590_R	1.429	0.76
445_L	459_I	1.428	0.75
210_K	309_L	1.427	0.75
353_L	358_V	1.427	0.75
560_K	568_G	1.412	0.75
292_Y	295_P	1.401	0.74
50_R	59_R	1.396	0.74
428_E	468_A	1.392	0.74
102_Q	106_K	1.390	0.73
404_E	407_K	1.390	0.73
574_E	577_Y	1.389	0.73
208_V	233_F	1.387	0.73
404_E	414_R	1.385	0.73
51_W	55_K	1.383	0.73
292_Y	296_E	1.376	0.73
42_L	45_A	1.372	0.72
519_A	522_C	1.372	0.72
54_S	58_E	1.369	0.72
388_K	392_K	1.362	0.72
238_Y	341_G	1.362	0.72
288_A	297_L	1.360	0.72
52_S	55_K	1.348	0.71
273_N	279_T	1.347	0.71
388_K	393_T	1.345	0.71
199_Q	313_G	1.340	0.71
416_E	596_R	1.331	0.70
14_A	92_A	1.324	0.70
16_T	243_V	1.322	0.70
71_S	82_T	1.320	0.69
605_K	609_S	1.320	0.69
561_A	566_Y	1.319	0.69
403_V	406_K	1.318	0.69
46_L	51_W	1.316	0.69
493_V	518_L	1.314	0.69
596_R	600_L	1.309	0.69
118_A	142_M	1.307	0.69
527_A	582_V	1.302	0.68
288_A	294_K	1.300	0.68
119_T	126_I	1.290	0.68
43_N	46_L	1.287	0.67
67_D	71_S	1.274	0.67
527_A	573_A	1.272	0.67
245_Y	270_F	1.270	0.66
389_L	392_K	1.268	0.66
154_V	174_A	1.267	0.66
127_S	159_G	1.265	0.66
497_A	550_Q	1.255	0.65
10_L	83_V	1.241	0.65
238_Y	277_V	1.240	0.65
417_P	596_R	1.231	0.64
366_K	370_G	1.229	0.64
411_L	414_R	1.225	0.64
455_R	604_E	1.225	0.64
51_W	59_R	1.222	0.63
52_S	56_L	1.218	0.63
475_F	545_G	1.213	0.63
46_L	55_K	1.211	0.63
431_N	461_G	1.208	0.62
407_K	411_L	1.207	0.62
50_R	55_K	1.206	0.62
267_E	271_K	1.206	0.62
439_S	488_T	1.205	0.62
385_R	391_I	1.203	0.62
551_R	555_L	1.201	0.62
508_N	591_F	1.199	0.62
455_R	603_A	1.197	0.62
289_P	294_K	1.188	0.61
617_I	620_G	1.186	0.61
377_D	380_I	1.185	0.61
55_K	60_G	1.178	0.60
108_D	111_L	1.177	0.60
560_K	565_I	1.172	0.60
570_M	576_A	1.166	0.60
289_P	293_V	1.166	0.60
404_E	454_V	1.164	0.59
256_I	259_D	1.164	0.59
289_P	292_Y	1.163	0.59
559_G	562_K	1.156	0.59
420_A	448_L	1.148	0.58
79_L	103_V	1.146	0.58
438_V	492_V	1.143	0.58
24_I	27_I	1.140	0.58
558_K	561_A	1.139	0.58
422_I	457_V	1.137	0.58
312_A	361_A	1.137	0.58
193_V	326_I	1.136	0.58
560_K	567_T	1.133	0.57
412_I	415_I	1.132	0.57
80_D	84_S	1.131	0.57
42_L	46_L	1.130	0.57
521_A	550_Q	1.127	0.57
563_L	579_M	1.121	0.57
226_L	307_P	1.115	0.56
334_L	337_R	1.112	0.56
89_S	110_L	1.110	0.56
519_A	525_R	1.109	0.56
478_L	483_V	1.106	0.56
269_K	274_E	1.106	0.56
61_Q	64_E	1.103	0.55
88_F	142_M	1.102	0.55
424_L	431_N	1.094	0.55
390_G	393_T	1.090	0.54
221_V	307_P	1.089	0.54
407_K	413_I	1.087	0.54
140_V	170_T	1.072	0.53
9_I	30_Y	1.069	0.53
428_E	437_L	1.067	0.53
376_P	379_M	1.066	0.53
365_L	372_N	1.060	0.52
39_Q	42_L	1.060	0.52
372_N	375_N	1.060	0.52
82_T	112_P	1.059	0.52
235_L	244_A	1.056	0.52
407_K	410_T	1.054	0.52
101_R	132_A	1.051	0.52
491_N	626_W	1.049	0.52
50_R	61_Q	1.046	0.51
643_K	647_E	1.046	0.51
382_Q	385_R	1.045	0.51
49_I	52_S	1.044	0.51
376_P	381_T	1.042	0.51
543_I	635_L	1.041	0.51
288_A	293_V	1.037	0.51
467_S	516_L	1.036	0.51
44_N	50_R	1.035	0.51
445_L	492_V	1.034	0.50
312_A	358_V	1.029	0.50
265_L	269_K	1.026	0.50
383_M	386_E	1.024	0.50
293_V	296_E	1.023	0.50
377_D	386_E	1.023	0.50
560_K	563_L	1.021	0.50
288_A	292_Y	1.018	0.49
551_R	554_R	1.018	0.49
49_I	58_E	1.016	0.49
289_P	297_L	1.016	0.49
115_A	138_K	1.015	0.49
196_I	318_A	1.014	0.49
377_D	383_M	1.008	0.49
255_G	258_D	1.008	0.49
379_M	384_I	1.008	0.49
152_Q	180_Q	1.007	0.49
49_I	59_R	1.004	0.48
649_V	653_L	1.004	0.48
387_N	391_I	1.003	0.48
89_S	107_L	1.002	0.48
397_F	401_G	1.001	0.48
52_S	61_Q	0.999	0.48
614_K	617_I	0.997	0.48
391_I	394_G	0.994	0.48
287_P	290_G	0.991	0.47
80_D	110_L	0.988	0.47
89_S	138_K	0.987	0.47
374_F	392_K	0.983	0.47
292_Y	297_L	0.983	0.47
60_G	64_E	0.982	0.47
190_G	250_S	0.981	0.47
242_D	278_K	0.980	0.47
576_A	582_V	0.971	0.46
607_P	611_L	0.970	0.46
386_E	389_L	0.967	0.46
269_K	273_N	0.966	0.46
344_K	352_E	0.964	0.46
207_L	313_G	0.963	0.46
494_N	550_Q	0.962	0.45
55_K	61_Q	0.958	0.45
623_S	627_T	0.955	0.45
46_L	52_S	0.955	0.45
129_I	243_V	0.955	0.45
377_D	382_Q	0.953	0.45
193_V	314_G	0.950	0.45
610_L	614_K	0.947	0.44
375_N	392_K	0.945	0.44
519_A	533_L	0.942	0.44
550_Q	554_R	0.942	0.44
53_L	57_Q	0.940	0.44
607_P	614_K	0.939	0.44
489_L	493_V	0.939	0.44
192_V	432_A	0.939	0.44
507_I	531_A	0.938	0.44
486_L	637_G	0.937	0.44
151_M	238_Y	0.936	0.44
111_L	114_H	0.935	0.44
359_L	362_L	0.932	0.43
563_L	581_L	0.932	0.43
507_I	519_A	0.931	0.43
365_L	384_I	0.931	0.43
301_L	304_K	0.930	0.43
182_I	192_V	0.928	0.43
167_A	183_M	0.927	0.43
107_L	110_L	0.926	0.43
369_S	374_F	0.925	0.43
389_L	393_T	0.925	0.43
16_T	24_I	0.924	0.43
606_S	614_K	0.920	0.43
7_K	364_D	0.919	0.42
126_I	130_A	0.915	0.42
424_L	461_G	0.913	0.42
407_K	415_I	0.911	0.42
200_I	235_L	0.911	0.42
8_K	33_Y	0.911	0.42
52_S	60_G	0.910	0.42
387_N	392_K	0.907	0.42
545_G	549_T	0.906	0.42
56_L	59_R	0.906	0.42
386_E	394_G	0.904	0.41
245_Y	262_I	0.904	0.41
225_K	307_P	0.904	0.41
59_R	62_I	0.899	0.41
43_N	50_R	0.898	0.41
48_R	58_E	0.898	0.41
171_Y	183_M	0.895	0.41
46_L	61_Q	0.895	0.41
533_L	582_V	0.894	0.41
47_E	51_W	0.892	0.41
49_I	54_S	0.891	0.41
460_T	592_E	0.887	0.40
471_D	474_S	0.887	0.40
432_A	437_L	0.884	0.40
76_I	106_K	0.884	0.40
442_D	495_K	0.884	0.40
585_V	588_S	0.884	0.40
51_W	61_Q	0.882	0.40
11_V	15_G	0.881	0.40
60_G	63_K	0.881	0.40
532_Q	539_N	0.879	0.40
593_E	597_R	0.878	0.40
89_S	115_A	0.877	0.40
416_E	600_L	0.874	0.39
188_V	325_G	0.873	0.39
553_P	556_V	0.873	0.39
268_Q	271_K	0.872	0.39
357_T	361_A	0.871	0.39
54_S	59_R	0.870	0.39
45_A	49_I	0.868	0.39
8_K	31_K	0.868	0.39
375_N	378_P	0.867	0.39
375_N	382_Q	0.867	0.39
244_A	340_L	0.866	0.39
373_T	377_D	0.866	0.39
41_I	47_E	0.865	0.39
418_P	600_L	0.865	0.39
12_V	110_L	0.865	0.39
205_C	236_I	0.862	0.39
224_Y	243_V	0.862	0.39
434_N	471_D	0.861	0.39
228_F	235_L	0.860	0.38
405_E	414_R	0.852	0.38
630_T	641_T	0.852	0.38
460_T	508_N	0.849	0.38
475_F	542_I	0.849	0.38
46_L	53_L	0.849	0.38
484_I	641_T	0.848	0.38
503_I	523_D	0.847	0.38
43_N	49_I	0.845	0.38
26_A	543_I	0.844	0.37
480_P	650_K	0.843	0.37
211_K	306_N	0.843	0.37
419_L	456_V	0.842	0.37
637_G	641_T	0.842	0.37
644_D	647_E	0.842	0.37
107_L	111_L	0.841	0.37
403_V	409_N	0.841	0.37
377_D	394_G	0.841	0.37
46_L	57_Q	0.841	0.37
444_S	457_V	0.839	0.37
557_G	560_K	0.839	0.37
419_L	604_E	0.836	0.37
377_D	381_T	0.836	0.37
415_I	421_W	0.836	0.37
43_N	58_E	0.834	0.37
42_L	50_R	0.831	0.37
374_F	377_D	0.830	0.37
605_K	610_L	0.830	0.37
262_I	266_I	0.828	0.36
173_L	527_A	0.827	0.36
442_D	492_V	0.822	0.36
383_M	394_G	0.820	0.36
182_I	335_G	0.818	0.36
129_I	139_V	0.816	0.36
49_I	56_L	0.815	0.36
445_L	496_I	0.815	0.36
49_I	61_Q	0.813	0.35
12_V	24_I	0.811	0.35
410_T	414_R	0.811	0.35
378_P	391_I	0.810	0.35
434_N	489_L	0.810	0.35
235_L	260_I	0.809	0.35
386_E	392_K	0.809	0.35
42_L	58_E	0.808	0.35
497_A	554_R	0.807	0.35
270_F	280_G	0.807	0.35
516_L	533_L	0.807	0.35
201_N	236_I	0.806	0.35
647_E	651_A	0.805	0.35
381_T	385_R	0.805	0.35
66_V	69_I	0.804	0.35
43_N	47_E	0.803	0.35
520_M	570_M	0.801	0.35
365_L	368_L	0.801	0.35
97_M	128_K	0.801	0.35
42_L	104_F	0.801	0.35
39_Q	46_L	0.797	0.34
315_V	353_L	0.797	0.34
211_K	309_L	0.797	0.34
20_G	92_A	0.795	0.34
608_I	615_L	0.795	0.34
43_N	59_R	0.795	0.34
94_T	99_I	0.794	0.34
380_I	384_I	0.792	0.34
521_A	551_R	0.792	0.34
107_L	117_L	0.789	0.34
436_E	439_S	0.789	0.34
385_R	392_K	0.787	0.34
384_I	389_L	0.786	0.34
388_K	394_G	0.786	0.34
404_E	411_L	0.784	0.34
193_V	520_M	0.783	0.34
80_D	113_P	0.781	0.33
558_K	567_T	0.780	0.33
111_L	117_L	0.779	0.33
119_T	124_L	0.776	0.33
420_A	447_E	0.776	0.33
435_P	545_G	0.775	0.33
386_E	391_I	0.774	0.33
48_R	57_Q	0.774	0.33
599_A	603_A	0.773	0.33
527_A	576_A	0.770	0.33
42_L	60_G	0.769	0.33
9_I	32_V	0.766	0.32
370_G	394_G	0.764	0.32
163_S	217_E	0.763	0.32
557_G	562_K	0.763	0.32
321_L	324_E	0.760	0.32
476_I	480_P	0.760	0.32
605_K	608_I	0.758	0.32
49_I	53_L	0.758	0.32
249_K	267_E	0.756	0.32
234_E	277_V	0.755	0.32
507_I	511_A	0.753	0.32
374_F	381_T	0.753	0.32
359_L	363_E	0.752	0.32
498_L	625_I	0.751	0.32
214_D	301_L	0.750	0.31
165_E	169_I	0.749	0.31
80_D	109_E	0.749	0.31
306_N	313_G	0.749	0.31
180_Q	196_I	0.748	0.31
374_F	386_E	0.745	0.31
300_E	305_L	0.744	0.31
196_I	336_V	0.744	0.31
462_N	508_N	0.742	0.31
50_R	53_L	0.742	0.31
404_E	415_I	0.740	0.31
50_R	60_G	0.739	0.31
118_A	170_T	0.739	0.31
156_V	171_Y	0.739	0.31
106_K	136_Q	0.738	0.31
377_D	391_I	0.737	0.31
630_T	634_T	0.737	0.31
376_P	394_G	0.736	0.31
48_R	51_W	0.736	0.31
607_P	615_L	0.735	0.31
549_T	628_G	0.735	0.31
630_T	638_L	0.733	0.30
560_K	564_M	0.733	0.30
433_L	437_L	0.733	0.30
365_L	375_N	0.732	0.30
367_A	372_N	0.731	0.30
614_K	618_E	0.729	0.30
383_M	388_K	0.728	0.30
468_A	478_L	0.728	0.30
480_P	646_E	0.728	0.30
48_R	52_S	0.727	0.30
14_A	34_L	0.727	0.30
208_V	235_L	0.727	0.30
374_F	378_P	0.727	0.30
375_N	391_I	0.726	0.30
630_T	633_S	0.725	0.30
441_L	445_L	0.725	0.30
235_L	340_L	0.724	0.30
405_E	412_I	0.723	0.30
526_I	598_V	0.722	0.30
287_P	297_L	0.720	0.30
577_Y	582_V	0.720	0.30
404_E	410_T	0.719	0.30
409_N	434_N	0.718	0.30
375_N	385_R	0.718	0.30
200_I	228_F	0.716	0.29
382_Q	388_K	0.716	0.29
390_G	394_G	0.716	0.29
46_L	59_R	0.716	0.29
42_L	49_I	0.715	0.29
83_V	107_L	0.711	0.29
50_R	54_S	0.710	0.29
51_W	60_G	0.709	0.29
201_N	204_S	0.709	0.29
7_K	117_L	0.707	0.29
211_K	305_L	0.707	0.29
431_N	463_G	0.705	0.29
292_Y	307_P	0.703	0.29
608_I	611_L	0.703	0.29
591_F	594_E	0.703	0.29
378_P	381_T	0.703	0.29
363_E	366_K	0.702	0.29
224_Y	231_G	0.700	0.29
89_S	134_K	0.700	0.29
342_L	489_L	0.700	0.29
494_N	551_R	0.698	0.28
205_C	248_S	0.697	0.28
412_I	420_A	0.696	0.28
38_S	76_I	0.695	0.28
370_G	374_F	0.695	0.28
372_N	376_P	0.695	0.28
598_V	601_K	0.694	0.28
157_M	222_A	0.694	0.28
56_L	78_G	0.694	0.28
560_K	569_D	0.694	0.28
350_A	358_V	0.694	0.28
405_E	432_A	0.693	0.28
18_G	21_I	0.692	0.28
176_K	590_R	0.691	0.28
607_P	612_A	0.690	0.28
105_S	132_A	0.690	0.28
388_K	391_I	0.688	0.28
609_S	612_A	0.687	0.28
108_D	132_A	0.687	0.28
105_S	109_E	0.686	0.28
46_L	60_G	0.686	0.28
365_L	376_P	0.685	0.28
634_T	642_T	0.684	0.28
190_G	338_L	0.683	0.28
201_N	244_A	0.683	0.28
465_A	510_F	0.683	0.28
380_I	383_M	0.682	0.28
58_E	62_I	0.682	0.28
605_K	615_L	0.682	0.28
381_T	386_E	0.681	0.27
378_P	383_M	0.678	0.27
585_V	591_F	0.678	0.27
583_D	588_S	0.677	0.27
408_M	411_L	0.677	0.27
380_I	394_G	0.676	0.27
66_V	574_E	0.676	0.27
42_L	51_W	0.675	0.27
374_F	383_M	0.675	0.27
608_I	614_K	0.674	0.27
47_E	50_R	0.673	0.27
108_D	117_L	0.673	0.27
97_M	124_L	0.673	0.27
380_I	386_E	0.673	0.27
249_K	252_E	0.673	0.27
555_L	583_D	0.671	0.27
373_T	376_P	0.670	0.27
6_I	9_I	0.670	0.27
441_L	446_D	0.670	0.27
117_L	132_A	0.670	0.27
141_G	232_V	0.669	0.27
101_R	105_S	0.669	0.27
438_V	489_L	0.667	0.27
25_A	90_I	0.666	0.27
405_E	444_S	0.666	0.27
381_T	392_K	0.665	0.27
141_G	158_K	0.665	0.27
157_M	232_V	0.665	0.27
378_P	382_Q	0.665	0.27
93_S	265_L	0.663	0.26
312_A	316_N	0.661	0.26
376_P	386_E	0.661	0.26
203_A	313_G	0.660	0.26
610_L	613_A	0.660	0.26
49_I	57_Q	0.660	0.26
368_L	372_N	0.659	0.26
366_K	372_N	0.659	0.26
287_P	294_K	0.658	0.26
377_D	384_I	0.657	0.26
385_R	394_G	0.657	0.26
374_F	391_I	0.657	0.26
397_F	402_K	0.657	0.26
123_S	250_S	0.656	0.26
41_I	49_I	0.655	0.26
124_L	304_K	0.655	0.26
406_K	411_L	0.653	0.26
494_N	497_A	0.653	0.26
360_K	363_E	0.652	0.26
58_E	63_K	0.652	0.26
75_T	103_V	0.652	0.26
462_N	588_S	0.651	0.26
51_W	57_Q	0.651	0.26
455_R	599_A	0.651	0.26
445_L	449_E	0.650	0.26
435_P	439_S	0.649	0.26
38_S	74_T	0.649	0.26
265_L	283_F	0.648	0.26
418_P	599_A	0.647	0.26
433_L	519_A	0.647	0.26
234_E	280_G	0.646	0.26
370_G	384_I	0.646	0.26
74_T	77_V	0.646	0.26
525_R	582_V	0.646	0.26
6_I	533_L	0.645	0.26
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45_A	50_R	0.645	0.26
366_K	383_M	0.644	0.25
55_K	64_E	0.644	0.25
141_G	222_A	0.644	0.25
381_T	394_G	0.644	0.25
381_T	387_N	0.643	0.25
387_N	393_T	0.641	0.25
358_V	361_A	0.640	0.25
109_E	113_P	0.640	0.25
52_S	57_Q	0.639	0.25
119_T	129_I	0.638	0.25
377_D	388_K	0.638	0.25
373_T	384_I	0.638	0.25
162_T	166_T	0.637	0.25
57_Q	61_Q	0.637	0.25
385_R	388_K	0.637	0.25
83_V	89_S	0.637	0.25
567_T	581_L	0.636	0.25
84_S	300_E	0.636	0.25
428_E	444_S	0.635	0.25
459_I	543_I	0.634	0.25
370_G	373_T	0.634	0.25
384_I	393_T	0.632	0.25
41_I	45_A	0.630	0.25
42_L	52_S	0.628	0.25
611_L	617_I	0.628	0.25
385_R	389_L	0.628	0.25
373_T	378_P	0.628	0.25
201_N	205_C	0.627	0.25
235_L	263_C	0.626	0.25
192_V	602_I	0.626	0.25
501_K	523_D	0.626	0.25
146_N	237_D	0.625	0.24
161_K	522_C	0.625	0.24
151_M	307_P	0.624	0.24
57_Q	86_A	0.623	0.24
402_K	414_R	0.622	0.24
207_L	310_I	0.622	0.24
39_Q	45_A	0.622	0.24
38_S	42_L	0.622	0.24
44_N	55_K	0.621	0.24
337_R	597_R	0.621	0.24
129_I	501_K	0.621	0.24
552_L	555_L	0.620	0.24
630_T	643_K	0.620	0.24
106_K	267_E	0.619	0.24
214_D	217_E	0.619	0.24
298_P	357_T	0.619	0.24
284_Y	474_S	0.618	0.24
377_D	385_R	0.618	0.24
165_E	279_T	0.617	0.24
25_A	196_I	0.617	0.24
494_N	626_W	0.617	0.24
647_E	650_K	0.616	0.24
404_E	413_I	0.616	0.24
420_A	444_S	0.616	0.24
89_S	114_H	0.615	0.24
203_A	207_L	0.615	0.24
224_Y	280_G	0.614	0.24
372_N	377_D	0.612	0.24
488_T	492_V	0.612	0.24
86_A	115_A	0.612	0.24
437_L	497_A	0.611	0.24
384_I	391_I	0.610	0.24
366_K	385_R	0.609	0.24
511_A	516_L	0.608	0.24
117_L	134_K	0.608	0.24
126_I	141_G	0.607	0.24
450_S	453_D	0.606	0.23
382_Q	394_G	0.606	0.23
471_D	477_T	0.606	0.23
384_I	387_N	0.606	0.23
380_I	387_N	0.605	0.23
456_V	459_I	0.604	0.23
378_P	386_E	0.604	0.23
49_I	60_G	0.604	0.23
326_I	332_I	0.602	0.23
42_L	54_S	0.602	0.23
232_V	623_S	0.600	0.23
274_E	279_T	0.600	0.23
10_L	33_Y	0.599	0.23
215_Y	497_A	0.598	0.23
378_P	389_L	0.598	0.23
380_I	392_K	0.597	0.23
392_K	397_F	0.597	0.23
254_L	579_M	0.595	0.23
84_S	164_D	0.595	0.23
369_S	394_G	0.593	0.23
378_P	384_I	0.592	0.23
331_D	526_I	0.591	0.23
43_N	51_W	0.591	0.23
375_N	383_M	0.590	0.23
54_S	432_A	0.590	0.23
461_G	508_N	0.590	0.23
597_R	601_K	0.589	0.23
588_S	591_F	0.589	0.23
109_E	115_A	0.588	0.23
395_S	398_Y	0.588	0.23
46_L	56_L	0.588	0.23
341_G	484_I	0.588	0.23
487_R	630_T	0.586	0.22
610_L	615_L	0.586	0.22
95_E	120_N	0.586	0.22
463_G	508_N	0.586	0.22
583_D	586_V	0.585	0.22
218_V	433_L	0.585	0.22
140_V	589_N	0.584	0.22
30_Y	69_I	0.584	0.22
43_N	60_G	0.583	0.22
45_A	48_R	0.583	0.22
376_P	399_Q	0.583	0.22
384_I	394_G	0.582	0.22
208_V	511_A	0.582	0.22
231_G	265_L	0.582	0.22
373_T	381_T	0.581	0.22
358_V	362_L	0.581	0.22
624_N	640_F	0.579	0.22
490_R	629_Q	0.578	0.22
373_T	392_K	0.578	0.22
46_L	54_S	0.578	0.22
12_V	312_A	0.577	0.22
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200_I	489_L	0.576	0.22
391_I	395_S	0.575	0.22
193_V	340_L	0.575	0.22
151_M	225_K	0.574	0.22
580_G	599_A	0.573	0.22
381_T	384_I	0.573	0.22
472_V	653_L	0.572	0.22
193_V	525_R	0.572	0.22
61_Q	65_S	0.571	0.22
119_T	255_G	0.571	0.22
192_V	325_G	0.571	0.22
216_R	284_Y	0.570	0.22
41_I	52_S	0.566	0.22
8_K	169_I	0.566	0.22
42_L	59_R	0.565	0.21
118_A	154_V	0.565	0.21
33_Y	86_A	0.564	0.21
300_E	418_P	0.563	0.21
183_M	331_D	0.563	0.21
207_L	309_L	0.563	0.21
376_P	388_K	0.563	0.21
432_A	524_I	0.562	0.21
101_R	133_T	0.561	0.21
222_A	228_F	0.561	0.21
382_Q	386_E	0.561	0.21
482_D	485_R	0.561	0.21
214_D	520_M	0.561	0.21
204_S	433_L	0.561	0.21
472_V	540_I	0.560	0.21
374_F	385_R	0.560	0.21
467_S	521_A	0.559	0.21
202_I	553_P	0.558	0.21
435_P	484_I	0.558	0.21
446_D	450_S	0.558	0.21
123_S	190_G	0.557	0.21
152_Q	589_N	0.557	0.21
370_G	375_N	0.556	0.21
477_T	480_P	0.555	0.21
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268_Q	578_K	0.555	0.21
381_T	388_K	0.554	0.21
184_I	202_I	0.554	0.21
271_K	522_C	0.554	0.21
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417_P	600_L	0.553	0.21
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364_D	556_V	0.553	0.21
387_N	390_G	0.552	0.21
471_D	545_G	0.552	0.21
437_L	440_E	0.552	0.21
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206_I	210_K	0.551	0.21
412_I	422_I	0.550	0.21
558_K	568_G	0.550	0.21
113_P	167_A	0.550	0.21
89_S	117_L	0.549	0.21
624_N	627_T	0.549	0.21
493_V	508_N	0.548	0.21
386_E	390_G	0.547	0.21
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307_P	310_I	0.547	0.21
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198_G	236_I	0.547	0.21
531_A	570_M	0.547	0.21
255_G	259_D	0.547	0.21
99_I	103_V	0.546	0.21
41_I	44_N	0.546	0.21
107_L	337_R	0.546	0.21
229_P	235_L	0.546	0.21
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43_N	52_S	0.544	0.21
56_L	61_Q	0.544	0.21
523_D	602_I	0.544	0.21
377_D	389_L	0.542	0.20
23_E	149_V	0.542	0.20
374_F	394_G	0.542	0.20
366_K	377_D	0.541	0.20
376_P	384_I	0.541	0.20
17_M	21_I	0.541	0.20
57_Q	62_I	0.540	0.20
224_Y	260_I	0.540	0.20
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231_G	338_L	0.540	0.20
611_L	618_E	0.539	0.20
366_K	373_T	0.539	0.20
455_R	600_L	0.539	0.20
587_P	591_F	0.538	0.20
442_D	488_T	0.538	0.20
635_L	642_T	0.538	0.20
607_P	613_A	0.537	0.20
141_G	307_P	0.537	0.20
231_G	424_L	0.536	0.20
264_S	267_E	0.536	0.20
136_Q	166_T	0.535	0.20
179_K	514_G	0.535	0.20
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211_K	302_A	0.534	0.20
577_Y	581_L	0.534	0.20
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568_G	575_D	0.532	0.20
322_L	329_R	0.531	0.20
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582_V	635_L	0.529	0.20
602_I	605_K	0.528	0.20
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332_I	349_Y	0.526	0.20
433_L	493_V	0.526	0.20
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406_K	412_I	0.524	0.20
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259_D	321_L	0.523	0.20
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543_I	651_A	0.523	0.20
357_T	360_K	0.523	0.20
384_I	392_K	0.522	0.20
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552_L	588_S	0.521	0.19
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378_P	385_R	0.520	0.19
50_R	56_L	0.519	0.19
291_K	295_P	0.519	0.19
284_Y	424_L	0.518	0.19
505_A	511_A	0.518	0.19
396_G	399_Q	0.518	0.19
445_L	499_Y	0.518	0.19
406_K	425_N	0.518	0.19
7_K	378_P	0.518	0.19
44_N	77_V	0.517	0.19
411_L	415_I	0.517	0.19
44_N	49_I	0.517	0.19
28_S	49_I	0.516	0.19
508_N	528_S	0.516	0.19
14_A	104_F	0.516	0.19
151_M	226_L	0.515	0.19
284_Y	592_E	0.515	0.19
43_N	61_Q	0.515	0.19
443_K	447_E	0.514	0.19
377_D	393_T	0.513	0.19
410_T	440_E	0.512	0.19
640_F	650_K	0.512	0.19
72_R	196_I	0.512	0.19
286_Y	291_K	0.512	0.19
150_L	490_R	0.511	0.19
558_K	569_D	0.511	0.19
56_L	60_G	0.510	0.19
208_V	218_V	0.510	0.19
583_D	587_P	0.510	0.19
585_V	598_V	0.510	0.19
213_A	221_V	0.510	0.19
237_D	276_G	0.509	0.19
48_R	156_V	0.509	0.19
376_P	383_M	0.509	0.19
491_N	630_T	0.508	0.19
268_Q	363_E	0.507	0.19
467_S	645_V	0.507	0.19
172_D	241_V	0.507	0.19
376_P	380_I	0.506	0.19
8_K	106_K	0.506	0.19
449_E	499_Y	0.506	0.19
21_I	36_D	0.504	0.19
16_T	299_K	0.504	0.19
383_M	392_K	0.504	0.19
200_I	546_A	0.503	0.19
264_S	268_Q	0.503	0.19
199_Q	314_G	0.503	0.19
558_K	565_I	0.503	0.19
392_K	395_S	0.503	0.19
13_G	18_G	0.502	0.19
520_M	533_L	0.502	0.19
500_T	565_I	0.502	0.19
251_R	308_A	0.501	0.19
226_L	528_S	0.501	0.19
508_N	511_A	0.501	0.19
499_Y	564_M	0.501	0.19
137_D	267_E	0.500	0.19
376_P	392_K	0.500	0.19

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1wdkA	2	0.5792	100	0.648	Contact Map
2wtbA	1	0.5505	100	0.653	Contact Map
3zwcA	1	0.6003	100	0.655	Contact Map
3k6jA	1	0.5596	100	0.657	Contact Map
1zcjA	1	0.5988	100	0.659	Contact Map
4b3hA	1	0.5686	100	0.673	Contact Map
3mogA	3	0.5822	100	0.684	Contact Map
4j0eA	2	0.4299	100	0.737	Contact Map
1f0yA	2	0.4284	100	0.746	Contact Map
4r1nA	2	0.4238	100	0.753	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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