GREMLIN Database
PCKG - Phosphoenolpyruvate carboxykinase [GTP]
UniProt: Q97VS5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 603 (556)
Sequences: 898 (416)
Seq/√Len: 17.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
421_A563_Y5.5821.00
329_E345_R5.5641.00
40_E120_K4.8741.00
560_I581_K4.6231.00
458_R462_N4.5901.00
36_V44_V4.5491.00
498_S525_K4.1791.00
381_N384_N4.0711.00
251_Y391_D4.0371.00
61_A153_P3.9331.00
28_L147_V3.8051.00
408_E472_K3.7041.00
311_W338_S3.6941.00
413_S576_E3.6781.00
200_N230_E3.5981.00
510_A517_L3.5361.00
319_E374_S3.4851.00
498_S502_K3.4751.00
59_K63_E3.3831.00
502_K507_T3.3761.00
427_R437_E3.3480.99
304_A312_E3.1230.99
112_L199_N3.1170.99
513_T518_I2.9460.99
80_D213_S2.9250.99
372_L378_L2.8870.98
90_E432_I2.8710.98
283_E287_K2.8650.98
348_N352_R2.8050.98
51_D55_E2.7450.98
295_V375_F2.7260.98
520_F523_D2.6220.97
249_I505_E2.6210.97
54_K58_R2.5940.97
242_G379_D2.5150.96
427_R434_K2.5040.96
187_D190_K2.4930.96
244_N270_N2.4900.96
32_L46_L2.4760.96
69_R72_T2.4580.96
350_E359_K2.4430.95
165_I169_D2.4120.95
95_L111_G2.4050.95
422_S563_Y2.3980.95
525_K532_L2.3580.94
408_E474_F2.3520.94
58_R67_E2.3510.94
234_L463_F2.3460.94
69_R76_T2.3430.94
434_K437_E2.3370.94
314_L320_V2.3220.94
106_K114_E2.2990.94
250_H501_V2.2470.93
58_R76_T2.2460.93
571_S575_N2.2430.93
115_M119_L2.2360.93
326_L361_A2.2160.92
467_L470_S2.1980.92
427_R432_I2.1890.92
111_G194_M2.1620.91
45_Y56_Y2.1590.91
285_L389_I2.1510.91
508_A523_D2.1240.91
167_F171_S2.1180.90
61_A67_E2.0980.90
279_I390_I2.0890.90
339_E346_G2.0660.89
243_F265_T2.0570.89
250_H505_E2.0540.89
44_V149_V2.0300.88
304_A311_W2.0100.88
67_E157_H1.9980.88
352_R359_K1.9860.87
36_V39_C1.9610.87
140_S143_Q1.9530.86
449_M453_L1.9500.86
394_I500_A1.9460.86
243_F497_V1.9350.86
417_I559_I1.9210.85
485_K540_E1.8830.84
40_E124_R1.8730.84
158_S369_T1.8600.84
579_M583_R1.8300.83
160_N165_I1.8120.82
508_A520_F1.8090.82
142_F280_R1.8070.82
145_L169_D1.8060.82
35_V180_V1.8050.82
557_E581_K1.7910.81
23_I46_L1.7480.79
42_D124_R1.7450.79
60_K153_P1.7140.78
482_D487_L1.7130.78
392_G500_A1.7010.78
115_M194_M1.6860.77
55_E59_K1.6820.77
541_Y545_F1.6730.76
33_N37_K1.6680.76
373_T383_D1.6540.75
240_I390_I1.6490.75
411_S576_E1.6270.74
511_I514_P1.6260.74
142_F289_V1.6190.74
487_L543_K1.6170.74
134_S139_N1.5940.73
27_P175_K1.5930.73
410_F583_R1.5900.72
242_G381_N1.5560.71
510_A523_D1.5540.71
253_T390_I1.5460.70
282_F386_N1.5350.70
378_L383_D1.5260.69
133_Y179_F1.5250.69
54_K76_T1.5160.69
279_I286_P1.5140.69
131_G165_I1.5140.69
410_F512_Y1.5100.68
420_G513_T1.5080.68
249_I391_D1.4950.68
402_T551_K1.4940.68
32_L36_V1.4920.67
287_K389_I1.4880.67
250_H391_D1.4840.67
47_I53_E1.4590.66
319_E371_P1.4490.65
250_H504_V1.4470.65
313_V375_F1.4460.65
453_L566_F1.4380.64
253_T279_I1.4350.64
372_L383_D1.4180.63
114_E118_L1.4090.63
51_D160_N1.3900.62
417_I563_Y1.3890.62
242_G272_I1.3720.61
247_K507_T1.3610.60
449_M457_L1.3580.60
518_I545_F1.3560.60
116_L120_K1.3500.59
68_I79_F1.3500.59
345_R354_D1.3430.59
128_M149_V1.3360.59
59_K69_R1.3360.59
303_N339_E1.3330.58
482_D485_K1.3190.58
563_Y577_L1.3180.58
575_N579_M1.3150.57
60_K64_S1.3150.57
560_I578_K1.3030.57
576_E583_R1.3020.57
566_F569_I1.3000.56
303_N338_S1.2970.56
558_R561_E1.2940.56
407_V419_I1.2920.56
508_A522_E1.2910.56
427_R435_S1.2820.55
553_L585_V1.2820.55
432_I437_E1.2760.55
249_I507_T1.2740.55
55_E69_R1.2640.54
134_S163_Y1.2630.54
112_L201_T1.2630.54
188_I191_R1.2570.54
102_Y446_L1.2520.54
577_L581_K1.2490.53
325_V366_A1.2490.53
548_K551_K1.2420.53
228_A360_P1.2400.53
97_D109_N1.2390.53
148_Q155_V1.2350.53
35_V39_C1.2320.52
547_I584_I1.2280.52
30_E34_S1.2270.52
23_I29_I1.2270.52
234_L360_P1.2230.52
410_F576_E1.2180.52
106_K110_E1.2130.51
306_D401_S1.2100.51
97_D198_A1.2020.51
27_P178_R1.1990.50
287_K386_N1.1990.50
502_K525_K1.1990.50
134_S142_F1.1970.50
118_L457_L1.1950.50
134_S280_R1.1950.50
39_C180_V1.1840.49
424_E555_K1.1750.49
58_R157_H1.1680.48
372_L382_W1.1620.48
142_F227_K1.1570.48
569_I574_I1.1570.48
308_P366_A1.1510.47
107_P110_E1.1490.47
242_G251_Y1.1430.47
240_I277_A1.1350.46
119_L203_Y1.1320.46
454_S457_L1.1310.46
413_S582_E1.1280.46
512_Y517_L1.1270.46
134_S145_L1.1200.46
139_N142_F1.1160.45
526_A541_Y1.1140.45
58_R62_L1.1120.45
240_I272_I1.1030.45
96_S226_M1.0990.44
47_I165_I1.0960.44
408_E503_R1.0950.44
449_M566_F1.0920.44
537_G540_E1.0900.44
147_V177_L1.0900.44
536_Y541_Y1.0880.44
68_I327_M1.0850.43
482_D543_K1.0810.43
427_R433_G1.0680.42
62_L76_T1.0660.42
122_S180_V1.0640.42
309_I312_E1.0620.42
413_S461_L1.0590.42
303_N340_L1.0580.42
465_K572_E1.0530.42
521_Y536_Y1.0500.41
348_N353_W1.0500.41
440_F558_R1.0490.41
575_N578_K1.0460.41
28_L170_F1.0430.41
413_S464_G1.0320.40
540_E543_K1.0310.40
66_E111_G1.0290.40
312_E315_H1.0240.40
61_A157_H1.0230.40
563_Y573_V1.0180.40
313_V374_S1.0180.40
411_S582_E1.0170.39
64_S153_P1.0150.39
509_N523_D1.0130.39
422_S440_F1.0130.39
234_L462_N1.0090.39
200_N224_T1.0080.39
403_L552_Y1.0030.39
344_E354_D1.0030.39
39_C45_Y1.0020.39
457_L573_V0.9990.38
311_W314_L0.9960.38
25_N176_F0.9950.38
117_T120_K0.9950.38
159_E215_G0.9930.38
305_R340_L0.9870.38
521_Y541_Y0.9850.38
91_D192_R0.9810.37
163_Y219_L0.9790.37
67_E76_T0.9790.37
187_D205_V0.9770.37
564_L574_I0.9750.37
109_N113_S0.9740.37
402_T457_L0.9730.37
423_M481_K0.9720.37
133_Y219_L0.9720.37
226_M230_E0.9680.37
153_P156_I0.9660.37
77_I347_Y0.9660.37
474_F500_A0.9640.36
554_E557_E0.9610.36
119_L408_E0.9600.36
252_F392_G0.9590.36
509_N520_F0.9550.36
63_E280_R0.9530.36
26_Y30_E0.9510.36
285_L391_D0.9420.35
409_A419_I0.9410.35
394_I483_D0.9400.35
413_S575_N0.9400.35
473_I501_V0.9390.35
414_H576_E0.9380.35
402_T438_L0.9380.35
310_I371_P0.9380.35
185_E191_R0.9360.35
179_F202_V0.9320.35
135_L207_T0.9260.34
79_F487_L0.9260.34
220_A272_I0.9200.34
226_M229_V0.9180.34
265_T577_L0.9170.34
251_Y379_D0.9160.34
173_N176_F0.9090.33
183_K186_P0.9040.33
131_G338_S0.9040.33
369_T449_M0.9020.33
536_Y544_Q0.9020.33
474_F510_A0.9020.33
134_S289_V0.9000.33
202_V497_V0.9000.33
40_E121_G0.8980.33
458_R582_E0.8970.33
433_G436_D0.8960.33
501_V505_E0.8950.33
281_E467_L0.8950.33
417_I577_L0.8940.33
521_Y545_F0.8940.33
413_S572_E0.8930.33
539_E542_E0.8920.32
103_V439_E0.8920.32
67_E78_H0.8910.32
32_L39_C0.8900.32
308_P487_L0.8890.32
399_D552_Y0.8860.32
265_T566_F0.8840.32
252_F501_V0.8820.32
511_I520_F0.8800.32
390_I569_I0.8800.32
56_Y60_K0.8790.32
560_I564_L0.8720.31
561_E565_K0.8700.31
554_E564_L0.8690.31
411_S564_L0.8690.31
407_V475_G0.8690.31
245_G249_I0.8650.31
83_L432_I0.8640.31
83_L189_K0.8640.31
341_P344_E0.8630.31
94_I102_Y0.8630.31
251_Y389_I0.8590.31
252_F550_R0.8590.31
23_I243_F0.8580.31
180_V199_N0.8580.31
279_I394_I0.8560.31
139_N174_T0.8550.31
454_S566_F0.8510.30
144_I227_K0.8480.30
521_Y542_E0.8470.30
144_I219_L0.8460.30
147_V180_V0.8440.30
556_T580_Q0.8440.30
114_E190_K0.8430.30
483_D500_A0.8430.30
61_A66_E0.8430.30
482_D540_E0.8390.30
462_N466_R0.8390.30
128_M400_Y0.8380.30
265_T562_I0.8360.30
545_F562_I0.8350.29
280_R393_I0.8350.29
228_A394_I0.8340.29
485_K543_K0.8340.29
59_K249_I0.8340.29
399_D403_L0.8340.29
31_F334_Y0.8330.29
562_I576_E0.8310.29
243_F268_I0.8310.29
378_L382_W0.8200.29
54_K160_N0.8180.29
265_T521_Y0.8180.29
549_L553_L0.8160.29
111_G192_R0.8150.28
483_D487_L0.8140.28
268_I548_K0.8140.28
140_S384_N0.8130.28
242_G270_N0.8120.28
304_A315_H0.8110.28
559_I562_I0.8100.28
27_P176_F0.8090.28
306_D408_E0.8070.28
148_Q440_F0.8060.28
411_S465_K0.8030.28
78_H186_P0.8030.28
283_E389_I0.8030.28
52_E69_R0.8010.28
434_K554_E0.8000.28
57_I157_H0.7990.28
424_E577_L0.7990.28
270_N379_D0.7980.28
320_V370_V0.7980.28
326_L346_G0.7950.28
452_S566_F0.7940.27
62_L67_E0.7920.27
337_G427_R0.7890.27
487_L544_Q0.7890.27
406_V496_W0.7880.27
78_H201_T0.7880.27
254_A338_S0.7870.27
123_M182_S0.7850.27
52_E360_P0.7840.27
78_H199_N0.7840.27
54_K157_H0.7840.27
93_F196_D0.7830.27
180_V196_D0.7780.27
514_P584_I0.7780.27
556_T577_L0.7770.27
93_F104_N0.7740.26
348_N354_D0.7730.26
481_K551_K0.7720.26
464_G470_S0.7690.26
28_L31_F0.7680.26
523_D541_Y0.7670.26
345_R353_W0.7660.26
518_I521_Y0.7660.26
402_T556_T0.7600.26
524_L541_Y0.7600.26
265_T526_A0.7590.26
260_S273_S0.7580.26
424_E562_I0.7550.26
234_L416_V0.7540.26
576_E579_M0.7540.26
512_Y578_K0.7530.26
454_S568_D0.7520.25
133_Y186_P0.7520.25
143_Q372_L0.7510.25
443_M449_M0.7480.25
369_T453_L0.7480.25
93_F492_D0.7480.25
66_E78_H0.7460.25
97_D199_N0.7450.25
411_S470_S0.7420.25
134_S143_Q0.7410.25
116_L119_L0.7410.25
463_F466_R0.7410.25
187_D191_R0.7400.25
168_E171_S0.7380.25
503_R510_A0.7380.25
27_P173_N0.7370.25
47_I54_K0.7350.25
53_E160_N0.7340.25
366_A562_I0.7330.25
75_H423_M0.7320.25
260_S425_S0.7320.25
190_K205_V0.7310.25
177_L227_K0.7310.25
139_N382_W0.7310.25
150_T535_E0.7300.24
122_S435_S0.7300.24
183_K206_N0.7300.24
60_K254_A0.7280.24
134_S219_L0.7270.24
543_K546_T0.7260.24
93_F192_R0.7250.24
344_E355_R0.7240.24
521_Y538_K0.7230.24
113_S117_T0.7230.24
481_K518_I0.7230.24
91_D191_R0.7230.24
203_Y268_I0.7220.24
179_F379_D0.7220.24
438_L566_F0.7210.24
133_Y354_D0.7190.24
202_V241_V0.7180.24
545_F559_I0.7170.24
243_F252_F0.7160.24
440_F573_V0.7130.24
25_N174_T0.7130.24
369_T544_Q0.7120.24
245_G501_V0.7120.24
234_L420_G0.7110.24
343_P346_G0.7110.24
288_A449_M0.7100.24
35_V149_V0.7100.24
37_K120_K0.7100.24
186_P191_R0.7100.24
571_S582_E0.7090.24
90_E427_R0.7080.23
139_N145_L0.7050.23
147_V411_S0.7050.23
333_V364_P0.7040.23
314_L555_K0.7020.23
42_D481_K0.7020.23
316_K319_E0.7010.23
110_E114_E0.7010.23
162_L273_S0.7000.23
157_H573_V0.7000.23
334_Y339_E0.7000.23
153_P213_S0.6990.23
228_A231_E0.6980.23
465_K582_E0.6960.23
110_E113_S0.6960.23
234_L443_M0.6960.23
148_Q410_F0.6950.23
179_F219_L0.6940.23
114_E192_R0.6940.23
287_K332_D0.6930.23
303_N544_Q0.6930.23
342_K547_I0.6920.23
454_S469_K0.6920.23
124_R158_S0.6920.23
224_T230_E0.6910.23
36_V130_V0.6910.23
400_Y481_K0.6890.23
161_I369_T0.6880.23
27_P34_S0.6880.23
408_E579_M0.6880.23
78_H111_G0.6870.23
326_L366_A0.6870.23
66_E95_L0.6860.23
137_P163_Y0.6860.23
511_I521_Y0.6860.23
171_S569_I0.6850.22
252_F497_V0.6840.22
414_H452_S0.6830.22
28_L446_L0.6830.22
265_T541_Y0.6820.22
188_I432_I0.6810.22
78_H188_I0.6800.22
96_S198_A0.6790.22
73_S507_T0.6790.22
73_S561_E0.6780.22
314_L558_R0.6770.22
241_V272_I0.6750.22
402_T454_S0.6750.22
426_A519_P0.6740.22
303_N311_W0.6740.22
139_N372_L0.6710.22
309_I377_N0.6700.22
126_R301_G0.6690.22
514_P518_I0.6690.22
507_T554_E0.6690.22
462_N470_S0.6680.22
265_T559_I0.6680.22
279_I393_I0.6680.22
161_I371_P0.6680.22
110_E118_L0.6670.22
579_M582_E0.6670.22
492_D534_K0.6670.22
111_G115_M0.6660.22
417_I422_S0.6650.22
310_I370_V0.6630.22
268_I400_Y0.6610.21
31_F147_V0.6590.21
234_L561_E0.6560.21
444_A450_P0.6560.21
293_I383_D0.6530.21
248_G368_F0.6510.21
475_G559_I0.6510.21
438_L562_I0.6510.21
90_E433_G0.6510.21
134_S137_P0.6510.21
117_T252_F0.6500.21
137_P382_W0.6500.21
520_F524_L0.6490.21
31_F35_V0.6490.21
40_E98_T0.6480.21
78_H112_L0.6470.21
131_G409_A0.6460.21
109_N510_A0.6460.21
213_S377_N0.6450.21
124_R175_K0.6450.21
571_S578_K0.6440.21
449_M544_Q0.6440.21
54_K143_Q0.6420.21
243_F562_I0.6420.21
272_I496_W0.6420.21
374_S378_L0.6410.21
143_Q289_V0.6380.21
44_V411_S0.6380.21
438_L518_I0.6360.20
51_D54_K0.6360.20
159_E162_L0.6360.20
348_N359_K0.6350.20
303_N481_K0.6340.20
134_S165_I0.6340.20
106_K409_A0.6330.20
414_H420_G0.6330.20
31_F180_V0.6310.20
379_D541_Y0.6300.20
25_N134_S0.6300.20
380_K389_I0.6290.20
79_F438_L0.6280.20
433_G439_E0.6280.20
166_A170_F0.6260.20
350_E515_I0.6250.20
436_D439_E0.6250.20
511_I523_D0.6240.20
281_E470_S0.6240.20
295_V400_Y0.6220.20
231_E543_K0.6170.20
43_S60_K0.6170.20
295_V382_W0.6160.20
354_D357_S0.6160.20
29_I33_N0.6160.20
553_L557_E0.6150.20
464_G467_L0.6140.20
268_I573_V0.6130.20
25_N29_I0.6130.20
561_E568_D0.6120.20
143_Q423_M0.6120.20
380_K384_N0.6110.20
315_H320_V0.6110.20
557_E560_I0.6110.20
416_V555_K0.6100.19
75_H332_D0.6090.19
143_Q369_T0.6090.19
78_H191_R0.6080.19
137_P165_I0.6070.19
465_K571_S0.6070.19
511_I518_I0.6070.19
462_N465_K0.6070.19
340_L568_D0.6050.19
423_M449_M0.6050.19
142_F178_R0.6040.19
187_D432_I0.6030.19
39_C122_S0.6020.19
145_L179_F0.6010.19
393_I576_E0.6010.19
133_Y494_K0.6010.19
295_V313_V0.5990.19
386_N411_S0.5990.19
124_R538_K0.5990.19
282_F285_L0.5980.19
249_I504_V0.5970.19
245_G250_H0.5970.19
95_L194_M0.5960.19
213_S439_E0.5960.19
303_N560_I0.5960.19
454_S565_K0.5940.19
58_R61_A0.5940.19
394_I581_K0.5930.19
526_A569_I0.5930.19
455_R458_R0.5930.19
119_L182_S0.5920.19
51_D165_I0.5920.19
502_K547_I0.5910.19
130_V149_V0.5910.19
161_I321_I0.5900.19
180_V581_K0.5900.19
500_A504_V0.5890.19
63_E247_K0.5890.19
391_D420_G0.5880.19
264_S447_D0.5880.19
546_T550_R0.5860.19
123_M136_G0.5860.19
74_G122_S0.5860.19
272_I379_D0.5860.19
481_K548_K0.5850.19
52_E469_K0.5840.18
44_V109_N0.5840.18
410_F414_H0.5840.18
353_W356_E0.5830.18
22_S29_I0.5830.18
538_K542_E0.5820.18
399_D427_R0.5820.18
50_S524_L0.5820.18
149_V465_K0.5820.18
269_G456_Y0.5820.18
134_S169_D0.5810.18
393_I552_Y0.5810.18
423_M562_I0.5800.18
24_N485_K0.5800.18
414_H583_R0.5790.18
47_I156_I0.5780.18
111_G187_D0.5780.18
341_P568_D0.5780.18
420_G545_F0.5770.18
176_F461_L0.5770.18
507_T565_K0.5760.18
168_E247_K0.5760.18
38_L120_K0.5750.18
186_P206_N0.5750.18
240_I391_D0.5750.18
192_R402_T0.5740.18
302_I307_D0.5730.18
165_I394_I0.5720.18
268_I584_I0.5720.18
251_Y407_V0.5720.18
309_I373_T0.5710.18
119_L361_A0.5710.18
34_S37_K0.5710.18
371_P456_Y0.5700.18
544_Q562_I0.5660.18
409_A472_K0.5660.18
135_L273_S0.5650.18
102_Y453_L0.5630.18
312_E524_L0.5630.18
242_G308_P0.5630.18
141_P482_D0.5630.18
513_T545_F0.5620.18
148_Q189_K0.5620.18
180_V467_L0.5600.18
137_P289_V0.5590.18
147_V170_F0.5580.18
330_D511_I0.5570.18
427_R436_D0.5570.18
386_N574_I0.5570.18
329_E355_R0.5570.18
402_T475_G0.5560.17
474_F504_V0.5560.17
72_T75_H0.5560.17
83_L473_I0.5550.17
47_I163_Y0.5540.17
320_V371_P0.5540.17
71_Q79_F0.5540.17
199_N226_M0.5530.17
265_T545_F0.5520.17
78_H205_V0.5520.17
298_I302_I0.5510.17
139_N544_Q0.5510.17
466_R579_M0.5500.17
445_I460_Y0.5490.17
522_E541_Y0.5480.17
414_H559_I0.5470.17
132_F259_G0.5470.17
112_L180_V0.5470.17
417_I421_A0.5470.17
328_T332_D0.5470.17
481_K485_K0.5470.17
539_E561_E0.5460.17
252_F394_I0.5460.17
150_T414_H0.5450.17
512_Y572_E0.5450.17
402_T566_F0.5440.17
393_I521_Y0.5440.17
303_N562_I0.5440.17
424_E440_F0.5440.17
78_H185_E0.5430.17
57_I354_D0.5420.17
249_I282_F0.5420.17
45_Y443_M0.5420.17
410_F419_I0.5420.17
288_A332_D0.5410.17
457_L566_F0.5410.17
195_I485_K0.5400.17
578_K582_E0.5400.17
39_C44_V0.5400.17
526_A538_K0.5390.17
550_R568_D0.5390.17
492_D563_Y0.5380.17
410_F413_S0.5370.17
449_M562_I0.5370.17
148_Q469_K0.5360.17
104_N343_P0.5360.17
402_T449_M0.5360.17
252_F513_T0.5360.17
393_I526_A0.5350.17
327_M333_V0.5350.17
419_I472_K0.5350.17
455_R515_I0.5340.17
280_R289_V0.5330.17
413_S518_I0.5330.17
230_E462_N0.5320.17
179_F277_A0.5310.17
135_L162_L0.5310.17
492_D547_I0.5310.17
29_I37_K0.5300.17
194_M205_V0.5290.17
417_I526_A0.5290.17
507_T561_E0.5280.17
357_S360_P0.5280.17
559_I577_L0.5280.17
545_F553_L0.5270.16
517_L575_N0.5270.16
147_V341_P0.5250.16
403_L443_M0.5250.16
73_S356_E0.5250.16
395_F460_Y0.5250.16
501_V504_V0.5240.16
57_I500_A0.5240.16
106_K199_N0.5240.16
28_L160_N0.5240.16
571_S574_I0.5240.16
358_G440_F0.5230.16
69_R523_D0.5220.16
190_K194_M0.5220.16
466_R556_T0.5220.16
161_I370_V0.5220.16
58_R280_R0.5220.16
148_Q214_V0.5210.16
375_F544_Q0.5200.16
137_P145_L0.5200.16
206_N213_S0.5200.16
265_T279_I0.5200.16
321_I500_A0.5190.16
347_Y408_E0.5190.16
437_E472_K0.5190.16
133_Y178_R0.5180.16
179_F186_P0.5180.16
339_E343_P0.5180.16
210_A214_V0.5180.16
62_L69_R0.5180.16
25_N172_N0.5170.16
148_Q185_E0.5160.16
90_E190_K0.5150.16
41_P44_V0.5150.16
57_I156_I0.5150.16
144_I320_V0.5150.16
164_R383_D0.5150.16
101_P332_D0.5140.16
409_A457_L0.5140.16
186_P443_M0.5140.16
69_R109_N0.5130.16
69_R93_F0.5130.16
131_G168_E0.5120.16
438_L559_I0.5110.16
350_E357_S0.5100.16
458_R581_K0.5100.16
171_S174_T0.5090.16
137_P143_Q0.5090.16
514_P549_L0.5090.16
272_I407_V0.5090.16
78_H148_Q0.5090.16
240_I456_Y0.5080.16
411_S575_N0.5080.16
101_P446_L0.5070.16
114_E191_R0.5070.16
228_A414_H0.5070.16
550_R553_L0.5070.16
130_V176_F0.5070.16
103_V334_Y0.5070.16
134_S138_R0.5060.16
78_H187_D0.5060.16
454_S550_R0.5060.16
357_S576_E0.5060.16
419_I473_I0.5050.16
98_T384_N0.5050.16
518_I575_N0.5040.16
467_L521_Y0.5040.16
481_K486_F0.5040.16
207_T273_S0.5040.16
106_K201_T0.5040.16
188_I306_D0.5030.16
360_P505_E0.5030.16
369_T457_L0.5030.16
556_T576_E0.5030.16
64_S68_I0.5030.16
470_S515_I0.5030.16
356_E359_K0.5020.16
58_R78_H0.5020.16
401_S423_M0.5020.16
72_T128_M0.5010.16
66_E206_N0.5010.16
202_V252_F0.5010.16
352_R394_I0.5010.16
408_E517_L0.5010.16
30_E131_G0.5010.16
134_S449_M0.5010.16
458_R472_K0.5010.16
457_L475_G0.5010.16
494_K541_Y0.5010.16
34_S116_L0.5000.16
159_E273_S0.5000.16
51_D148_Q0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4gmuA 1 0.932 100 0.296 Contact Map
4r43A 1 0.9287 100 0.313 Contact Map
2fafA 1 0.9104 100 0.319 Contact Map
2zciA 2 0.9104 100 0.332 Contact Map
1ytmA 1 0.7794 100 0.663 Contact Map
1j3bA 2 0.7745 100 0.671 Contact Map
2olrA 1 0.801 100 0.679 Contact Map
1ii2A 2 0.7861 100 0.685 Contact Map
3tqfA 3 0.2156 46.4 0.988 Contact Map
1slmA 2 0.068 32.7 0.989 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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