GREMLIN Database
Q97VQ3 - Nitroreductase, bluB homolog, putative
UniProt: Q97VQ3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 227 (171)
Sequences: 8309 (5744)
Seq/√Len: 439.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
29_K139_E3.6881.00
23_P26_V3.2901.00
24_D52_R2.7371.00
24_D28_A2.6331.00
48_F128_A2.4181.00
47_N200_F2.3751.00
141_I174_Y2.2711.00
133_W143_V2.1791.00
142_G175_V2.1431.00
32_S35_H2.0941.00
30_I136_A2.0731.00
26_V139_E2.0141.00
101_T164_I1.9621.00
9_K137_T1.9311.00
5_E9_K1.8821.00
33_A135_A1.8571.00
26_V141_I1.8431.00
59_K157_I1.8091.00
18_K176_R1.7841.00
54_D58_K1.7251.00
34_A132_L1.7001.00
56_I59_K1.6691.00
30_I132_L1.6571.00
49_I101_T1.6511.00
3_V7_I1.6341.00
3_V6_A1.6231.00
58_K92_L1.6211.00
20_D174_Y1.6211.00
61_K92_L1.6071.00
60_I154_V1.5391.00
50_I96_V1.4951.00
133_W145_F1.4901.00
58_K62_Q1.4861.00
153_K156_E1.4711.00
193_L197_D1.4581.00
31_L199_V1.4381.00
136_A172_L1.4321.00
129_I168_S1.4301.00
28_A196_S1.4231.00
55_E58_K1.3991.00
4_Y29_K1.3921.00
15_S176_R1.3901.00
195_L199_V1.3851.00
8_R36_M1.3851.00
123_Y126_V1.3831.00
26_V174_Y1.3771.00
155_K166_L1.3761.00
129_I170_L1.3761.00
101_T160_I1.3711.00
48_F98_M1.3641.00
133_W170_L1.3541.00
150_N153_K1.3461.00
137_T142_G1.3431.00
63_V153_K1.3161.00
54_D57_R1.3001.00
35_H198_L1.2741.00
99_A169_Y1.2721.00
98_M132_L1.2711.00
30_I172_L1.2621.00
56_I157_I1.2611.00
63_V157_I1.2441.00
12_D144_G1.2421.00
100_V129_I1.2131.00
59_K62_Q1.2111.00
5_E8_R1.2001.00
30_I141_I1.1961.00
141_I172_L1.1961.00
26_V29_K1.1911.00
22_I141_I1.1901.00
99_A166_L1.1861.00
4_Y33_A1.1851.00
47_N164_I1.1621.00
127_L130_G1.1581.00
136_A143_V1.1561.00
28_A32_S1.1241.00
8_R32_S1.1151.00
55_E59_K1.1121.00
7_I131_N1.1091.00
17_Y171_T1.0981.00
62_Q66_E1.0911.00
125_T167_V1.0781.00
52_R96_V1.0731.00
4_Y8_R1.0721.00
28_A195_L1.0711.00
40_V120_T1.0631.00
143_V172_L1.0611.00
22_I174_Y1.0511.00
33_A139_E1.0231.00
100_V132_L1.0231.00
153_K157_I1.0211.00
103_D163_E1.0141.00
37_A131_N1.0141.00
50_I199_V1.0131.00
53_D56_I1.0101.00
100_V125_T1.0071.00
100_V170_L1.0071.00
25_E28_A1.0011.00
131_N134_L1.0011.00
120_T147_S0.9991.00
23_P174_Y0.9961.00
21_P52_R0.9941.00
4_Y139_E0.9931.00
145_F168_S0.9611.00
21_P54_D0.9601.00
32_S195_L0.9591.00
135_A138_A0.9481.00
135_A139_E0.9461.00
119_E122_L0.9411.00
129_I145_F0.9401.00
132_L170_L0.9331.00
152_E156_E0.9311.00
51_I99_A0.9221.00
146_V171_T0.9201.00
50_I98_M0.9191.00
47_N103_D0.9151.00
19_P93_D0.9081.00
132_L172_L0.9041.00
130_G134_L0.8931.00
104_P165_E0.8911.00
18_K174_Y0.8871.00
143_V170_L0.8851.00
90_A93_D0.8841.00
31_L50_I0.8731.00
87_K90_A0.8731.00
48_F100_V0.8681.00
6_A138_A0.8591.00
102_Y121_S0.8571.00
67_E70_R0.8551.00
118_P165_E0.8531.00
97_N169_Y0.8531.00
122_L167_V0.8491.00
22_I25_E0.8461.00
124_S147_S0.8391.00
3_V134_L0.8371.00
127_L131_N0.8361.00
123_Y147_S0.8331.00
29_K32_S0.8311.00
144_G171_T0.8251.00
38_P143_V0.8171.00
7_I134_L0.8141.00
87_K93_D0.8031.00
194_M197_D0.7981.00
56_I60_I0.7941.00
193_L198_L0.7931.00
29_K33_A0.7851.00
58_K61_K0.7791.00
64_V67_E0.7741.00
27_L31_L0.7721.00
30_I139_E0.7691.00
155_K165_E0.7601.00
20_D23_P0.7541.00
13_I179_P0.7501.00
3_V138_A0.7451.00
103_D164_I0.7421.00
160_I164_I0.7401.00
25_E29_K0.7391.00
17_Y144_G0.7391.00
40_V147_S0.7381.00
101_T166_L0.7381.00
4_Y135_A0.7361.00
98_M172_L0.7351.00
177_E180_K0.7331.00
27_L172_L0.7331.00
102_Y125_T0.7291.00
59_K63_V0.7231.00
149_F169_Y0.7231.00
49_I164_I0.7171.00
49_I158_L0.7151.00
22_I26_V0.7131.00
13_I175_V0.7121.00
27_L96_V0.7081.00
129_I133_W0.7001.00
119_E165_E0.7001.00
36_M189_W0.6991.00
123_Y127_L0.6981.00
112_L117_M0.6971.00
22_I95_P0.6961.00
154_V157_I0.6911.00
94_T97_N0.6841.00
99_A158_L0.6821.00
31_L34_A0.6811.00
4_Y138_A0.6801.00
51_I158_L0.6781.00
61_K65_E0.6731.00
39_S44_Q0.6711.00
152_E155_K0.6701.00
134_L138_A0.6671.00
119_E123_Y0.6671.00
128_A198_L0.6661.00
15_S179_P0.6621.00
18_K177_E0.6621.00
51_I60_I0.6571.00
40_V124_S0.6520.99
64_V68_R0.6500.99
127_L145_F0.6460.99
151_K166_L0.6310.99
34_A48_F0.6270.99
91_I97_N0.6240.99
66_E69_K0.6230.99
39_S46_W0.6220.99
97_N171_T0.6190.99
44_Q193_L0.6180.99
6_A134_L0.6170.99
102_Y167_V0.6160.99
46_W125_T0.6150.99
155_K160_I0.6140.99
7_I138_A0.6090.99
27_L50_I0.6070.99
60_I97_N0.6030.99
15_S177_E0.6030.99
11_R189_W0.6010.99
35_H48_F0.6000.99
96_V172_L0.6000.99
47_N193_L0.5970.99
155_K162_K0.5960.99
57_R61_K0.5950.99
160_I166_L0.5950.99
30_I33_A0.5930.99
104_P163_E0.5900.99
66_E153_K0.5890.99
122_L126_V0.5870.99
46_W128_A0.5850.99
49_I200_F0.5850.99
15_S93_D0.5840.99
105_N163_E0.5840.99
7_I33_A0.5790.99
126_V145_F0.5780.99
35_H195_L0.5780.99
112_L115_S0.5740.99
113_G116_T0.5680.99
161_P164_I0.5550.98
123_Y167_V0.5550.98
22_I27_L0.5540.98
46_W198_L0.5430.98
26_V30_I0.5420.98
8_R29_K0.5400.98
56_I158_L0.5310.98
103_D106_R0.5280.98
65_E69_K0.5280.98
10_R143_V0.5220.98
11_R179_P0.5210.98
142_G145_F0.5210.98
8_R33_A0.5200.98
118_P122_L0.5190.98
151_K165_E0.5180.97
95_P174_Y0.5170.97
37_A127_L0.5160.97
62_Q65_E0.5160.97
34_A37_A0.5150.97
18_K95_P0.5100.97
47_N101_T0.5090.97
21_P95_P0.5080.97
51_I56_I0.5060.97
122_L165_E0.5020.97
176_R179_P0.5010.97
21_P174_Y0.5000.97
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3n2sA 2 0.8678 100 0.203 Contact Map
1zchA 2 0.8634 100 0.203 Contact Map
1f5vA 2 0.8634 100 0.206 Contact Map
1bkjA 2 0.8502 100 0.21 Contact Map
3eofA 2 0.8634 100 0.246 Contact Map
2iskA 2 0.9075 100 0.247 Contact Map
3g14A 2 0.7753 100 0.261 Contact Map
3gagA 4 0.7621 100 0.27 Contact Map
1noxA 2 0.7577 100 0.272 Contact Map
3bemA 2 0.7665 100 0.273 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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