GREMLIN Database
Q97VN1 - Uncharacterized protein
UniProt: Q97VN1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 142 (119)
Sequences: 13346 (10250)
Seq/√Len: 939.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_T24_D2.7351.00
36_S101_H2.4651.00
18_V70_E2.3471.00
83_S106_D2.2941.00
81_V104_V2.2701.00
85_S89_E2.1681.00
79_V97_N2.1521.00
17_K20_T2.1071.00
81_V85_S2.0161.00
18_V47_V1.9691.00
82_K85_S1.9561.00
41_N45_Y1.9461.00
25_A69_V1.9221.00
16_V20_T1.9161.00
16_V37_V1.8331.00
5_S90_I1.8041.00
83_S112_I1.7211.00
16_V25_A1.7191.00
68_K71_N1.7031.00
14_V32_N1.6861.00
79_V99_I1.6231.00
38_V46_P1.6091.00
16_V39_I1.5831.00
81_V90_I1.5681.00
25_A50_F1.5011.00
100_R117_I1.4881.00
28_I32_N1.4801.00
6_R83_S1.4481.00
93_K97_N1.4071.00
103_V111_L1.3761.00
15_V40_V1.3421.00
23_I66_N1.3401.00
27_K31_Q1.3051.00
90_I102_I1.3021.00
81_V102_I1.2961.00
20_T28_I1.2781.00
79_V93_K1.2701.00
19_G70_E1.2681.00
50_F55_V1.2611.00
23_I27_K1.2561.00
80_T105_V1.2541.00
39_I73_G1.2531.00
52_E56_L1.2441.00
16_V69_V1.2411.00
21_K24_D1.2351.00
25_A37_V1.2321.00
50_F69_V1.2171.00
36_S49_I1.2121.00
17_K42_E1.2081.00
85_S93_K1.2031.00
6_R84_N1.1981.00
22_A72_L1.1751.00
86_S89_E1.1741.00
64_D67_D1.1631.00
8_L87_I1.1561.00
89_E93_K1.1561.00
14_V28_I1.1511.00
18_V42_E1.1391.00
24_D27_K1.1151.00
82_K106_D1.1101.00
46_P78_L1.1041.00
106_D110_K1.1021.00
46_P111_L1.0731.00
35_G52_E1.0671.00
92_E96_K1.0641.00
54_D74_T1.0601.00
44_D110_K1.0561.00
49_I103_V1.0561.00
38_V111_L1.0381.00
90_I115_V1.0261.00
24_D28_I0.9861.00
5_S81_V0.9851.00
50_F72_L0.9821.00
26_C55_V0.9801.00
40_V47_V0.9731.00
41_N47_V0.9631.00
106_D112_I0.9571.00
36_S100_R0.9561.00
8_L115_V0.9411.00
34_I37_V0.9291.00
81_V93_K0.9191.00
87_I120_I0.9121.00
52_E100_R0.9081.00
10_K119_D0.9021.00
101_H114_V0.8981.00
16_V28_I0.8901.00
19_G68_K0.8691.00
93_K102_I0.8591.00
67_D71_N0.8491.00
17_K40_V0.8441.00
18_V41_N0.8381.00
95_V122_N0.8291.00
14_V34_I0.8281.00
28_I37_V0.8281.00
56_L100_R0.8261.00
28_I31_Q0.8251.00
48_G73_G0.7881.00
47_V73_G0.7871.00
45_Y109_G0.7771.00
75_F78_L0.7731.00
45_Y110_K0.7671.00
46_P103_V0.7671.00
100_R118_K0.7501.00
69_V73_G0.7421.00
58_A61_C0.7241.00
63_K66_N0.7231.00
94_M102_I0.7221.00
57_R60_A0.7121.00
5_S115_V0.7111.00
9_I104_V0.7111.00
13_P38_V0.7071.00
38_V103_V0.7071.00
109_G112_I0.7021.00
101_H116_S0.6951.00
52_E118_K0.6871.00
40_V46_P0.6861.00
89_E92_E0.6861.00
36_S114_V0.6851.00
29_M37_V0.6691.00
70_E73_G0.6681.00
15_V44_D0.6641.00
56_L60_A0.6641.00
53_R100_R0.6631.00
80_T109_G0.6551.00
55_V58_A0.6521.00
85_S90_I0.6521.00
8_L123_E0.6471.00
40_V44_D0.6421.00
14_V37_V0.6421.00
10_K13_P0.6391.00
105_V111_L0.6391.00
70_E75_F0.6331.00
35_G117_I0.6311.00
34_I38_V0.6301.00
23_I65_L0.6281.00
58_A72_L0.6211.00
74_T77_K0.6181.00
35_G53_R0.6181.00
19_G42_E0.6171.00
35_G100_R0.6161.00
35_G38_V0.6101.00
49_I101_H0.6021.00
9_I113_G0.6011.00
105_V109_G0.5981.00
88_G92_E0.5981.00
118_K122_N0.5961.00
117_I121_V0.5961.00
74_T78_L0.5901.00
101_H117_I0.5831.00
35_G101_H0.5831.00
25_A29_M0.5781.00
21_K68_K0.5771.00
57_R61_C0.5751.00
46_P105_V0.5741.00
103_V112_I0.5721.00
30_Y61_C0.5711.00
17_K41_N0.5671.00
6_R106_D0.5631.00
38_V114_V0.5561.00
22_A58_A0.5561.00
26_C52_E0.5531.00
42_E45_Y0.5491.00
5_S9_I0.5491.00
121_V125_H0.5471.00
36_S51_T0.5401.00
114_V119_D0.5391.00
91_A120_I0.5381.00
41_N44_D0.5381.00
94_M117_I0.5341.00
82_K109_G0.5321.00
91_A121_V0.5301.00
49_I78_L0.5281.00
103_V114_V0.5241.00
115_V120_I0.5151.00
56_L59_V0.5111.00
94_M98_N0.5111.00
104_V112_I0.5091.00
38_V47_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l2bA 2 0.8239 99.9 0.251 Contact Map
4cooA 2 0.8803 99.9 0.289 Contact Map
3pc3A 2 0.8944 99.8 0.302 Contact Map
1pvmA 2 0.993 99.8 0.304 Contact Map
2rihA 2 0.9085 99.8 0.308 Contact Map
2qrdG 1 0.9296 99.8 0.309 Contact Map
2nycA 2 0.8662 99.8 0.314 Contact Map
2yziA 2 0.9366 99.8 0.314 Contact Map
2o16A 2 0.9437 99.8 0.314 Contact Map
3t4nC 1 0.9014 99.8 0.316 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0072 seconds.