GREMLIN Database
Q97VL2 - Uncharacterized protein
UniProt: Q97VL2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 166 (154)
Sequences: 113 (81)
Seq/√Len: 6.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
52_S67_T4.0540.95
78_T98_F2.8900.79
33_V140_L2.6220.71
124_I140_L2.5890.70
12_V90_P2.5740.70
8_I14_V2.4120.64
45_K76_L2.3760.63
104_A117_I2.3040.61
31_V55_I2.2830.60
29_G112_N2.2600.59
98_F123_K2.2180.57
149_Y153_Q2.2050.57
78_T123_K2.1660.56
39_P91_S2.0430.51
98_F125_H2.0160.50
11_V17_G1.9980.49
97_V108_L1.9970.49
63_D82_T1.9790.49
13_L28_T1.9740.48
96_E123_K1.9330.47
59_N89_I1.8210.43
16_A19_V1.7960.42
116_K151_N1.7830.41
35_I95_N1.7450.40
126_I153_Q1.7090.39
36_Q81_M1.6510.37
101_I104_A1.6110.35
35_I43_G1.6110.35
152_G159_S1.5860.35
126_I161_T1.5720.34
56_H65_W1.5450.33
17_G116_K1.5320.33
127_I140_L1.5240.33
116_K124_I1.5230.32
69_S134_G1.4740.31
115_A125_H1.3980.29
50_I67_T1.3750.28
47_Y162_A1.3670.28
46_I76_L1.3670.28
31_V58_V1.3380.27
50_I117_I1.3310.27
101_I117_I1.3210.26
51_S97_V1.3210.26
27_T82_T1.3210.26
51_S63_D1.3110.26
8_I82_T1.3000.26
9_V45_K1.2880.25
57_K88_R1.2830.25
61_S90_P1.2800.25
75_I113_I1.2690.25
36_Q144_F1.2580.24
55_I89_I1.2360.24
34_Y102_S1.2220.24
60_A90_P1.2160.23
51_S129_G1.2100.23
30_V139_S1.2060.23
51_S127_I1.2020.23
69_S135_G1.2010.23
9_V28_T1.1800.22
80_N98_F1.1790.22
130_M138_Q1.1790.22
26_L63_D1.1720.22
93_Q126_I1.1690.22
50_I132_L1.1610.22
20_Y117_I1.1210.21
124_I160_I1.1090.21
73_I82_T1.0830.20
116_K120_G1.0790.20
17_G68_I1.0660.20
141_L159_S1.0570.19
93_Q135_G1.0430.19
43_G113_I1.0410.19
61_S66_I1.0370.19
75_I144_F1.0180.19
31_V52_S1.0150.18
12_V59_N1.0080.18
48_L59_N1.0050.18
8_I61_S1.0040.18
46_I145_P1.0030.18
106_V159_S1.0020.18
46_I157_S0.9850.18
65_W84_L0.9800.18
120_G140_L0.9650.17
132_L141_L0.9640.17
39_P144_F0.9500.17
140_L151_N0.9460.17
53_I74_T0.9440.17
55_I141_L0.9430.17
113_I136_S0.9420.17
110_N131_D0.9390.17
27_T62_N0.9300.17
19_V143_S0.9300.17
28_T68_I0.9170.16
21_Y30_V0.9110.16
152_G162_A0.9050.16
79_S131_D0.9050.16
43_G151_N0.9000.16
47_Y76_L0.8950.16
84_L145_P0.8890.16
83_F133_K0.8890.16
51_S66_I0.8860.16
15_L59_N0.8760.16
120_G130_M0.8740.16
82_T102_S0.8730.15
133_K136_S0.8710.15
103_F124_I0.8700.15
95_N106_V0.8650.15
76_L143_S0.8530.15
96_E142_I0.8520.15
53_I63_D0.8480.15
27_T51_S0.8450.15
127_I148_T0.8410.15
78_T144_F0.8360.15
37_D118_P0.8350.15
36_Q78_T0.8260.15
61_S111_V0.8260.15
45_K105_Q0.8250.15
20_Y90_P0.8080.14
130_M154_I0.8050.14
53_I70_N0.7990.14
49_T77_L0.7920.14
60_A128_N0.7920.14
36_Q123_K0.7920.14
15_L97_V0.7890.14
31_V63_D0.7860.14
30_V159_S0.7790.14
79_S147_I0.7790.14
93_Q129_G0.7740.14
13_L57_K0.7700.14
14_V154_I0.7630.13
39_P117_I0.7620.13
29_G85_A0.7600.13
136_S151_N0.7570.13
35_I113_I0.7550.13
106_V138_Q0.7540.13
124_I148_T0.7540.13
123_K144_F0.7390.13
97_V127_I0.7370.13
68_I114_S0.7320.13
55_I136_S0.7310.13
16_A59_N0.7290.13
116_K161_T0.7200.13
38_P46_I0.7180.13
56_H70_N0.7100.13
33_V147_I0.7090.13
111_V115_A0.7030.12
53_I111_V0.7000.12
78_T125_H0.6980.12
10_I13_L0.6980.12
92_G119_S0.6980.12
14_V40_T0.6950.12
75_I126_I0.6940.12
134_G153_Q0.6930.12
104_A125_H0.6910.12
117_I144_F0.6880.12
71_K105_Q0.6840.12
106_V140_L0.6830.12
39_P99_L0.6820.12
28_T32_N0.6800.12
145_P157_S0.6780.12
58_V152_G0.6760.12
25_Y108_L0.6740.12
31_V50_I0.6690.12
38_P119_S0.6660.12
115_A133_K0.6650.12
116_K136_S0.6590.12
70_N105_Q0.6530.12
55_I117_I0.6510.12
95_N129_G0.6500.12
106_V127_I0.6490.12
16_A147_I0.6490.12
98_F119_S0.6420.12
23_F29_G0.6390.11
116_K140_L0.6330.11
140_L146_H0.6310.11
11_V14_V0.6260.11
12_V133_K0.6260.11
108_L116_K0.6230.11
64_S160_I0.6230.11
18_G108_L0.6180.11
66_I110_N0.6110.11
48_L143_S0.6090.11
143_S154_I0.6080.11
66_I127_I0.6070.11
21_Y26_L0.6070.11
34_Y40_T0.6040.11
127_I160_I0.6030.11
46_I115_A0.6030.11
82_T93_Q0.6000.11
139_S160_I0.5990.11
31_V44_V0.5980.11
54_M146_H0.5960.11
63_D103_F0.5950.11
32_N97_V0.5940.11
25_Y161_T0.5920.11
65_W119_S0.5910.11
21_Y58_V0.5900.11
96_E125_H0.5850.11
36_Q46_I0.5810.11
98_F145_P0.5780.11
33_V67_T0.5770.11
17_G26_L0.5660.10
20_Y104_A0.5630.10
130_M143_S0.5630.10
86_S107_Q0.5620.10
78_T96_E0.5540.10
140_L162_A0.5540.10
65_W98_F0.5540.10
46_I55_I0.5510.10
93_Q127_I0.5480.10
123_K142_I0.5480.10
34_Y49_T0.5450.10
30_V141_L0.5450.10
119_S123_K0.5430.10
74_T101_I0.5380.10
65_W92_G0.5370.10
13_L32_N0.5360.10
142_I160_I0.5360.10
62_N103_F0.5350.10
30_V35_I0.5320.10
104_A141_L0.5290.10
104_A144_F0.5290.10
11_V15_L0.5210.10
62_N66_I0.5130.10
28_T134_G0.5120.10
30_V156_I0.5070.10
21_Y157_S0.5070.10
33_V74_T0.5060.10
19_V154_I0.5020.10
41_S101_I0.5010.10
12_V127_I0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3pmqA 1 0.6807 87.1 0.919 Contact Map
4lm8A 1 0.7229 81.4 0.924 Contact Map
4ombA 1 0.8434 71.5 0.93 Contact Map
4fajA 1 0.6566 69.6 0.931 Contact Map
3ry3A 1 0.6265 67.9 0.932 Contact Map
4qflA 1 0.6566 66 0.933 Contact Map
4lmhA 3 0.7711 62.4 0.935 Contact Map
4peuA 1 0.6988 56.8 0.937 Contact Map
3sbqA 2 0.4518 56.4 0.937 Contact Map
4n4rB 1 0.7169 52.3 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0061 seconds.