Q97VD9 - SULSO - GREMLIN Contacts

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Q97VD9 - Mercuric reductase (Hg(II) reductase) (MerA)

UniProt:	Q97VD9	Sequences: MEDLVIIGYGAAGFAALIRANELGIKPVVVGYGEIGGTCVNVGCVPSKRMLRIGELYNYSSKVIGKKLFPEFFQAFQDKAEIVNSLRKEKYEDVINSYDIKLKIGKAYFTSPNAVKVNGEIIEAKKFIIATGSSPNIPNIKGLTEVGFWTNVEALSPDKTISSLAIIGGRALALEFAQMYKRLGVDTTILQRSGRILPDWEPEISLSVKNYLEENDSIPIFTNVRVKEVRKGNGGKIIVTDKGEVEADEILLATGRKPNVDLNLDAAGIELNDKGGIKVNEELRTSNPNVFAAGDVIGGPMLEALAGRQGSIAAENAIMNVHRKIDMLSVPQVVFIEPNVAKVGLTALEAVKEGYDIDQRVVKMDNIAKARILRENYGLIKMVIDKKFRNILGVQMFGKYAAEVINEAALALRFRATIDDLIDTIHVFPTMGESLRIAALAFTGDVSKMSCCV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	453 (436)
Sequences:	14229 (9367)
Seq/√Len:	448.6

ECOLI - STHA GSHR DLDH RCLA HCAD NORW
BACSU - DLDH1 DLDH2 DLDH3
HALSA - DLDH Q9HSN0 Q9HP48 Q9HR27
SULSO - Q97VD9 Q97Z19 Q97XZ3 Q97WE3 Q97VQ4 Q97Y24 Q97YT2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
165_A	247_A	4.412	1.00
32_Y	106_K	4.378	1.00
280_N	284_R	4.308	1.00
163_S	186_D	3.179	1.00
270_E	278_K	3.048	1.00
394_V	408_A	3.046	1.00
186_D	219_P	2.909	1.00
188_T	221_F	2.863	1.00
134_S	261_D	2.757	1.00
111_S	114_A	2.708	1.00
356_D	387_K	2.688	1.00
407_E	426_H	2.645	1.00
114_A	121_I	2.627	1.00
209_K	213_E	2.580	1.00
16_A	128_I	2.498	1.00
385_D	388_F	2.453	1.00
263_N	266_A	2.429	1.00
28_V	103_K	2.419	1.00
134_S	259_N	2.402	1.00
160_T	185_V	2.400	1.00
124_A	127_F	2.383	1.00
356_D	386_K	2.379	1.00
108_Y	116_K	2.350	1.00
136_N	257_K	2.308	1.00
389_R	419_D	2.282	1.00
163_S	248_D	2.269	1.00
5_V	122_I	2.262	1.00
202_P	348_L	2.258	1.00
345_L	350_A	2.254	1.00
358_D	386_K	2.244	1.00
390_N	415_R	2.221	1.00
116_K	121_I	2.198	1.00
141_K	228_E	2.190	1.00
165_A	190_L	2.177	1.00
313_A	317_A	2.176	1.00
12_A	293_A	2.171	1.00
345_L	353_E	2.130	1.00
4_L	20_A	2.123	1.00
230_R	238_I	2.116	1.00
396_M	401_A	2.039	1.00
272_N	276_G	2.028	1.00
5_V	115_V	2.027	1.00
411_A	416_A	2.023	1.00
5_V	30_V	2.004	1.00
113_N	289_N	1.977	1.00
228_E	238_I	1.949	1.00
110_T	116_K	1.933	1.00
150_T	153_E	1.932	1.00
357_I	383_V	1.920	1.00
174_L	189_I	1.916	1.00
236_K	244_E	1.887	1.00
347_A	351_V	1.881	1.00
194_G	223_N	1.867	1.00
134_S	257_K	1.867	1.00
126_K	289_N	1.865	1.00
114_A	123_E	1.845	1.00
30_V	122_I	1.837	1.00
105_G	117_V	1.813	1.00
110_T	121_I	1.799	1.00
181_K	186_D	1.797	1.00
347_A	381_K	1.778	1.00
236_K	246_E	1.777	1.00
230_R	236_K	1.756	1.00
128_I	317_A	1.740	1.00
3_D	125_K	1.740	1.00
348_L	352_K	1.739	1.00
5_V	124_A	1.705	1.00
109_F	127_F	1.703	1.00
3_D	26_K	1.684	1.00
7_I	107_A	1.684	1.00
129_I	296_V	1.680	1.00
284_R	288_P	1.676	1.00
165_A	237_I	1.672	1.00
382_M	394_V	1.668	1.00
164_L	180_Y	1.667	1.00
164_L	185_V	1.659	1.00
350_A	357_I	1.652	1.00
65_G	68_L	1.651	1.00
192_R	225_R	1.642	1.00
195_R	205_S	1.615	1.00
71_E	74_Q	1.613	1.00
5_V	28_V	1.611	1.00
339_N	402_A	1.608	1.00
238_I	244_E	1.591	1.00
174_L	336_I	1.577	1.00
355_Y	392_L	1.569	1.00
148_F	229_V	1.556	1.00
281_E	324_K	1.554	1.00
350_A	383_V	1.534	1.00
103_K	122_I	1.533	1.00
4_L	25_I	1.523	1.00
221_F	224_V	1.509	1.00
201_E	381_K	1.497	1.00
162_S	186_D	1.490	1.00
417_T	420_D	1.490	1.00
203_E	361_V	1.482	1.00
92_E	104_I	1.467	1.00
28_V	122_I	1.466	1.00
149_W	249_E	1.466	1.00
291_F	316_N	1.459	1.00
74_Q	77_Q	1.449	1.00
149_W	157_P	1.448	1.00
283_L	297_I	1.438	1.00
67_K	71_E	1.436	1.00
19_R	315_E	1.435	1.00
188_T	219_P	1.428	1.00
26_K	101_K	1.425	1.00
227_K	238_I	1.425	1.00
382_M	439_A	1.418	1.00
126_K	317_A	1.416	1.00
207_S	397_F	1.411	1.00
162_S	248_D	1.407	1.00
232_G	236_K	1.407	1.00
131_T	296_V	1.396	1.00
182_R	216_D	1.395	1.00
284_R	289_N	1.389	1.00
181_K	218_I	1.369	1.00
282_E	316_N	1.347	1.00
169_G	196_I	1.337	1.00
349_E	352_K	1.331	1.00
359_Q	383_V	1.330	1.00
203_E	381_K	1.314	1.00
4_L	128_I	1.307	1.00
224_V	241_D	1.304	1.00
56_L	59_Y	1.303	1.00
232_G	235_G	1.300	1.00
128_I	293_A	1.290	1.00
211_Y	214_E	1.279	1.00
225_R	240_T	1.276	1.00
154_A	180_Y	1.263	1.00
382_M	408_A	1.260	1.00
35_I	102_L	1.259	1.00
287_N	290_V	1.250	1.00
385_D	390_N	1.246	1.00
210_N	213_E	1.245	1.00
204_I	397_F	1.242	1.00
30_V	107_A	1.235	1.00
209_K	220_I	1.224	1.00
231_K	235_G	1.216	1.00
202_P	206_L	1.215	1.00
42_V	152_V	1.204	1.00
109_F	129_I	1.203	1.00
267_A	287_N	1.202	1.00
340_V	397_F	1.197	1.00
204_I	379_L	1.194	1.00
195_R	202_P	1.194	1.00
364_M	398_G	1.189	1.00
235_G	246_E	1.186	1.00
80_A	84_N	1.184	1.00
356_D	385_D	1.183	1.00
109_F	115_V	1.181	1.00
109_F	266_A	1.180	1.00
277_I	296_V	1.180	1.00
76_F	80_A	1.179	1.00
7_I	129_I	1.179	1.00
116_K	119_G	1.178	1.00
189_I	220_I	1.175	1.00
200_W	332_Q	1.172	1.00
347_A	359_Q	1.165	1.00
414_F	420_D	1.161	1.00
272_N	278_K	1.160	1.00
270_E	286_S	1.160	1.00
191_Q	222_T	1.158	1.00
264_L	269_I	1.158	1.00
269_I	277_I	1.151	1.00
229_V	250_I	1.147	1.00
347_A	357_I	1.146	1.00
310_G	314_A	1.142	1.00
293_A	313_A	1.141	1.00
108_Y	263_N	1.140	1.00
190_L	245_V	1.140	1.00
29_V	95_I	1.139	1.00
117_V	122_I	1.138	1.00
232_G	246_E	1.134	1.00
239_V	245_V	1.128	1.00
406_N	427_V	1.125	1.00
210_N	214_E	1.124	1.00
208_V	397_F	1.113	1.00
81_E	85_S	1.111	1.00
149_W	153_E	1.111	1.00
341_A	405_I	1.110	1.00
200_W	342_K	1.108	1.00
30_V	117_V	1.108	1.00
209_K	222_T	1.101	1.00
361_V	379_L	1.097	1.00
72_F	76_F	1.093	1.00
380_I	434_S	1.090	1.00
408_A	435_L	1.088	1.00
137_I	150_T	1.088	1.00
333_V	427_V	1.085	1.00
145_E	231_K	1.084	1.00
350_A	355_Y	1.078	1.00
167_I	250_I	1.078	1.00
190_L	239_V	1.078	1.00
110_T	114_A	1.078	1.00
147_G	231_K	1.077	1.00
355_Y	385_D	1.073	1.00
208_V	340_V	1.072	1.00
227_K	240_T	1.069	1.00
33_G	42_V	1.068	1.00
332_Q	342_K	1.062	1.00
349_E	353_E	1.059	1.00
103_K	120_E	1.058	1.00
351_V	357_I	1.052	1.00
195_R	209_K	1.047	1.00
329_S	412_L	1.036	1.00
67_K	74_Q	1.034	1.00
416_A	420_D	1.029	1.00
174_L	212_L	1.027	1.00
52_R	56_L	1.023	1.00
18_I	98_Y	1.020	1.00
113_N	117_V	1.017	1.00
269_I	287_N	1.010	1.00
221_F	245_V	1.008	1.00
163_S	185_V	1.008	1.00
358_D	389_R	1.007	1.00
283_L	313_A	1.002	1.00
165_A	245_V	1.002	1.00
77_Q	81_E	1.002	1.00
213_E	219_P	0.997	1.00
92_E	96_N	0.996	1.00
73_F	158_D	0.994	1.00
23_L	315_E	0.994	1.00
195_R	348_L	0.994	1.00
12_A	306_A	0.993	1.00
109_F	124_A	0.988	1.00
389_R	418_I	0.986	1.00
164_L	249_E	0.986	1.00
95_I	100_I	0.984	1.00
163_S	246_E	0.984	1.00
19_R	23_L	0.976	1.00
153_E	156_S	0.973	1.00
351_V	356_D	0.972	1.00
149_W	154_A	0.971	1.00
267_A	290_V	0.965	1.00
196_I	220_I	0.964	1.00
212_L	218_I	0.961	1.00
346_T	349_E	0.960	1.00
101_K	120_E	0.959	1.00
224_V	239_V	0.958	1.00
164_L	251_L	0.955	1.00
142_G	145_E	0.952	1.00
157_P	161_I	0.951	1.00
260_V	271_L	0.950	1.00
345_L	349_E	0.949	1.00
25_I	125_K	0.949	1.00
91_Y	95_I	0.944	1.00
279_V	297_I	0.944	1.00
333_V	402_A	0.942	1.00
313_A	316_N	0.939	1.00
20_A	314_A	0.933	1.00
343_V	412_L	0.933	1.00
23_L	318_I	0.933	1.00
93_D	97_S	0.930	1.00
406_N	432_G	0.929	1.00
109_F	267_A	0.929	1.00
9_Y	35_I	0.929	1.00
347_A	383_V	0.928	1.00
315_E	323_R	0.928	1.00
95_I	102_L	0.927	1.00
39_C	44_C	0.924	1.00
196_I	222_T	0.923	1.00
190_L	221_F	0.923	1.00
355_Y	383_V	0.920	1.00
204_I	395_Q	0.920	1.00
341_A	401_A	0.917	1.00
221_F	243_G	0.915	1.00
231_K	234_G	0.915	1.00
263_N	267_A	0.914	1.00
139_N	143_L	0.912	1.00
196_I	209_K	0.911	1.00
271_L	278_K	0.910	1.00
300_P	330_V	0.909	1.00
361_V	381_K	0.909	1.00
380_I	396_M	0.908	1.00
25_I	318_I	0.907	1.00
167_I	252_L	0.906	1.00
278_K	286_S	0.903	1.00
400_Y	403_E	0.902	1.00
25_I	126_K	0.902	1.00
109_F	263_N	0.902	1.00
173_A	191_Q	0.901	1.00
163_S	188_T	0.898	1.00
136_N	254_T	0.897	1.00
312_I	325_I	0.893	1.00
326_D	413_R	0.892	1.00
163_S	247_A	0.891	1.00
57_Y	61_S	0.891	1.00
312_I	316_N	0.888	1.00
284_R	316_N	0.886	1.00
169_G	191_Q	0.885	1.00
292_A	296_V	0.883	1.00
269_I	286_S	0.882	1.00
214_E	377_Y	0.882	1.00
391_I	408_A	0.881	1.00
230_R	244_E	0.874	1.00
190_L	224_V	0.872	1.00
9_Y	29_V	0.867	1.00
167_I	254_T	0.867	1.00
207_S	210_N	0.863	1.00
206_L	209_K	0.861	1.00
3_D	28_V	0.861	1.00
207_S	211_Y	0.860	1.00
3_D	25_I	0.860	1.00
279_V	292_A	0.857	1.00
7_I	262_L	0.856	1.00
30_V	105_G	0.851	1.00
411_A	421_L	0.851	1.00
284_R	291_F	0.850	1.00
127_F	290_V	0.850	1.00
314_A	318_I	0.849	1.00
258_P	276_G	0.847	1.00
144_T	147_G	0.845	1.00
283_L	316_N	0.845	1.00
159_K	249_E	0.845	1.00
142_G	147_G	0.844	1.00
358_D	384_I	0.835	1.00
15_A	307_G	0.835	1.00
240_T	243_G	0.833	1.00
211_Y	397_F	0.831	1.00
181_K	216_D	0.827	1.00
41_N	87_R	0.825	1.00
206_L	210_N	0.824	1.00
76_F	79_K	0.824	1.00
54_G	182_R	0.822	1.00
16_A	310_G	0.821	1.00
53_I	78_D	0.820	1.00
126_K	291_F	0.820	1.00
407_E	410_L	0.818	1.00
53_I	75_A	0.817	1.00
128_I	313_A	0.814	1.00
194_G	202_P	0.812	1.00
16_A	314_A	0.811	1.00
346_T	395_Q	0.811	1.00
108_Y	266_A	0.810	1.00
188_T	247_A	0.804	1.00
224_V	240_T	0.804	1.00
58_N	61_S	0.803	1.00
145_E	153_E	0.803	1.00
193_S	198_P	0.801	1.00
25_I	317_A	0.800	1.00
282_E	321_V	0.799	1.00
140_I	143_L	0.797	1.00
85_S	371_R	0.795	1.00
171_A	334_V	0.795	1.00
146_V	231_K	0.794	1.00
60_S	68_L	0.794	1.00
385_D	392_L	0.789	1.00
81_E	84_N	0.788	1.00
55_E	59_Y	0.787	1.00
166_I	251_L	0.784	1.00
201_E	395_Q	0.784	1.00
127_F	289_N	0.783	1.00
50_M	76_F	0.782	1.00
58_N	216_D	0.781	1.00
6_I	13_G	0.781	1.00
112_P	289_N	0.780	1.00
204_I	340_V	0.780	1.00
267_A	286_S	0.780	1.00
416_A	421_L	0.778	1.00
211_Y	216_D	0.778	1.00
5_V	127_F	0.775	1.00
267_A	271_L	0.775	1.00
350_A	392_L	0.775	1.00
136_N	139_N	0.773	1.00
315_E	320_N	0.771	1.00
343_V	409_A	0.765	1.00
58_N	62_K	0.759	1.00
391_I	412_L	0.759	1.00
383_V	386_K	0.758	1.00
84_N	89_E	0.758	1.00
89_E	93_D	0.757	1.00
47_S	51_L	0.754	1.00
212_L	220_I	0.753	1.00
83_V	86_L	0.752	1.00
261_D	265_D	0.752	1.00
268_G	287_N	0.751	1.00
284_R	287_N	0.751	1.00
264_L	271_L	0.750	1.00
177_A	189_I	0.749	1.00
211_Y	377_Y	0.749	1.00
51_L	179_M	0.748	1.00
191_Q	198_P	0.747	1.00
77_Q	158_D	0.747	1.00
408_A	412_L	0.744	1.00
19_R	314_A	0.743	1.00
90_K	94_V	0.742	1.00
60_S	63_V	0.741	1.00
20_A	25_I	0.741	1.00
6_I	17_L	0.739	1.00
276_G	301_M	0.738	1.00
21_N	100_I	0.738	1.00
7_I	115_V	0.736	1.00
166_I	173_A	0.736	1.00
177_A	218_I	0.735	1.00
47_S	176_F	0.734	1.00
31_G	34_E	0.733	1.00
285_T	292_A	0.733	1.00
113_N	287_N	0.731	1.00
28_V	101_K	0.731	1.00
89_E	92_E	0.731	1.00
80_A	156_S	0.731	1.00
16_A	313_A	0.730	1.00
236_K	239_V	0.729	1.00
382_M	438_A	0.729	1.00
21_N	27_P	0.728	1.00
105_G	118_N	0.727	1.00
167_I	226_V	0.727	1.00
54_G	57_Y	0.725	1.00
360_R	438_A	0.725	1.00
413_R	423_D	0.725	1.00
145_E	148_F	0.720	1.00
64_I	68_L	0.718	1.00
112_P	268_G	0.718	1.00
147_G	249_E	0.717	1.00
79_K	83_V	0.717	1.00
428_F	433_E	0.717	1.00
195_R	206_L	0.716	1.00
394_V	412_L	0.713	1.00
200_W	340_V	0.711	1.00
271_L	275_G	0.709	1.00
113_N	123_E	0.708	1.00
4_L	314_A	0.707	1.00
410_L	416_A	0.707	1.00
114_A	117_V	0.706	1.00
19_R	22_E	0.706	1.00
95_I	99_D	0.703	1.00
192_R	198_P	0.701	1.00
52_R	55_E	0.701	1.00
208_V	336_I	0.699	1.00
173_A	192_R	0.697	1.00
163_S	235_G	0.694	1.00
339_N	400_Y	0.693	1.00
410_L	424_T	0.690	1.00
390_N	417_T	0.686	1.00
137_I	252_L	0.686	1.00
137_I	143_L	0.685	1.00
376_N	399_K	0.683	1.00
133_S	256_R	0.681	1.00
79_K	156_S	0.681	1.00
388_F	415_R	0.680	1.00
63_V	68_L	0.678	1.00
305_L	330_V	0.677	1.00
138_P	252_L	0.676	1.00
93_D	96_N	0.673	1.00
396_M	404_V	0.672	1.00
260_V	276_G	0.671	1.00
277_I	292_A	0.667	1.00
84_N	87_R	0.666	1.00
80_A	83_V	0.666	1.00
364_M	434_S	0.666	1.00
197_L	208_V	0.664	1.00
82_I	86_L	0.664	1.00
283_L	312_I	0.664	1.00
179_M	183_L	0.661	1.00
363_K	366_N	0.661	1.00
410_L	414_F	0.660	1.00
77_Q	80_A	0.659	1.00
60_S	66_K	0.658	1.00
62_K	374_R	0.657	1.00
271_L	276_G	0.656	1.00
420_D	423_D	0.655	1.00
328_L	353_E	0.654	1.00
140_I	226_V	0.654	1.00
394_V	435_L	0.653	1.00
200_W	334_V	0.653	1.00
36_G	40_V	0.653	1.00
58_N	182_R	0.652	1.00
139_N	144_T	0.652	1.00
357_I	392_L	0.651	1.00
308_R	311_S	0.649	1.00
418_I	422_I	0.648	1.00
224_V	243_G	0.646	1.00
264_L	267_A	0.645	0.99
260_V	296_V	0.645	0.99
141_K	144_T	0.644	0.99
403_E	432_G	0.644	0.99
23_L	314_A	0.643	0.99
276_G	298_G	0.643	0.99
73_F	77_Q	0.642	0.99
182_R	337_E	0.641	0.99
178_Q	182_R	0.640	0.99
309_Q	327_M	0.640	0.99
410_L	421_L	0.637	0.99
30_V	103_K	0.637	0.99
137_I	142_G	0.637	0.99
360_R	384_I	0.636	0.99
34_E	42_V	0.635	0.99
23_L	320_N	0.634	0.99
142_G	146_V	0.633	0.99
279_V	283_L	0.631	0.99
207_S	379_L	0.630	0.99
18_I	22_E	0.630	0.99
20_A	27_P	0.628	0.99
394_V	405_I	0.626	0.99
269_I	290_V	0.626	0.99
141_K	145_E	0.625	0.99
204_I	207_S	0.625	0.99
75_A	78_D	0.625	0.99
20_A	317_A	0.625	0.99
174_L	220_I	0.625	0.99
81_E	86_L	0.623	0.99
369_K	372_I	0.618	0.99
339_N	431_M	0.617	0.99
188_T	245_V	0.617	0.99
273_D	278_K	0.615	0.99
180_Y	185_V	0.615	0.99
282_E	324_K	0.612	0.99
143_L	150_T	0.611	0.99
152_V	256_R	0.611	0.99
171_A	332_Q	0.610	0.99
178_Q	216_D	0.609	0.99
277_I	285_T	0.608	0.99
174_L	196_I	0.608	0.99
128_I	314_A	0.607	0.99
75_A	183_L	0.606	0.99
157_P	249_E	0.606	0.99
354_G	357_I	0.605	0.99
297_I	309_Q	0.604	0.99
22_E	98_Y	0.604	0.99
239_V	242_K	0.603	0.99
384_I	418_I	0.602	0.99
32_Y	259_N	0.602	0.99
51_L	55_E	0.602	0.99
305_L	327_M	0.602	0.99
78_D	81_E	0.598	0.99
216_D	337_E	0.598	0.99
271_L	277_I	0.597	0.99
74_Q	78_D	0.597	0.99
178_Q	212_L	0.596	0.99
34_E	87_R	0.595	0.99
143_L	252_L	0.594	0.99
112_P	267_A	0.593	0.99
12_A	130_A	0.593	0.99
76_F	158_D	0.591	0.99
91_Y	94_V	0.591	0.99
37_G	40_V	0.590	0.99
370_A	431_M	0.589	0.99
384_I	389_R	0.588	0.99
140_I	144_T	0.588	0.99
315_E	319_M	0.585	0.99
151_N	256_R	0.585	0.99
293_A	310_G	0.584	0.99
398_G	401_A	0.584	0.99
73_F	76_F	0.583	0.99
109_F	116_K	0.583	0.99
176_F	251_L	0.582	0.99
337_E	399_K	0.581	0.99
138_P	142_G	0.581	0.99
185_V	248_D	0.579	0.99
291_F	317_A	0.579	0.99
176_F	179_M	0.577	0.99
131_T	262_L	0.577	0.99
229_V	252_L	0.577	0.99
368_A	372_I	0.574	0.99
44_C	48_K	0.574	0.99
221_F	239_V	0.572	0.99
410_L	426_H	0.571	0.99
94_V	98_Y	0.570	0.99
190_L	247_A	0.569	0.99
14_F	29_V	0.568	0.99
308_R	312_I	0.566	0.99
76_F	81_E	0.564	0.99
421_L	439_A	0.562	0.99
348_L	351_V	0.562	0.99
308_R	436_R	0.561	0.99
345_L	355_Y	0.561	0.99
404_V	431_M	0.560	0.99
192_R	254_T	0.556	0.99
357_I	386_K	0.555	0.98
101_K	104_I	0.555	0.98
151_N	172_L	0.555	0.98
34_E	41_N	0.554	0.98
305_L	309_Q	0.552	0.98
55_E	58_N	0.549	0.98
371_R	376_N	0.548	0.98
191_Q	226_V	0.547	0.98
342_K	349_E	0.546	0.98
33_G	152_V	0.544	0.98
281_E	323_R	0.544	0.98
409_A	413_R	0.544	0.98
45_V	368_A	0.543	0.98
47_S	50_M	0.543	0.98
53_I	56_L	0.542	0.98
350_A	354_G	0.542	0.98
360_R	382_M	0.540	0.98
412_L	416_A	0.540	0.98
70_P	75_A	0.540	0.98
345_L	393_G	0.539	0.98
110_T	266_A	0.539	0.98
130_A	293_A	0.537	0.98
226_V	237_I	0.536	0.98
307_G	436_R	0.535	0.98
72_F	160_T	0.535	0.98
64_I	67_K	0.534	0.98
109_F	289_N	0.533	0.98
368_A	371_R	0.533	0.98
129_I	277_I	0.533	0.98
78_D	82_I	0.533	0.98
342_K	395_Q	0.530	0.98
148_F	250_I	0.529	0.98
413_R	424_T	0.528	0.98
39_C	48_K	0.528	0.98
163_S	249_E	0.527	0.98
138_P	143_L	0.527	0.98
72_F	158_D	0.527	0.98
163_S	181_K	0.527	0.98
79_K	155_L	0.524	0.98
246_E	249_E	0.523	0.98
38_T	151_N	0.523	0.98
53_I	57_Y	0.522	0.98
143_L	148_F	0.522	0.98
173_A	198_P	0.521	0.98
367_I	370_A	0.521	0.98
271_L	274_K	0.520	0.98
169_G	222_T	0.519	0.98
178_Q	337_E	0.518	0.98
36_G	39_C	0.518	0.98
364_M	431_M	0.518	0.98
346_T	383_V	0.516	0.98
29_V	102_L	0.515	0.98
92_E	102_L	0.515	0.98
395_Q	408_A	0.515	0.98
133_S	301_M	0.515	0.98
308_R	325_I	0.514	0.98
56_L	60_S	0.513	0.98
135_P	151_N	0.513	0.98
50_M	53_I	0.512	0.97
436_R	440_L	0.512	0.97
258_P	271_L	0.512	0.97
196_I	205_S	0.512	0.97
126_K	284_R	0.511	0.97
293_A	317_A	0.511	0.97
9_Y	31_G	0.510	0.97
82_I	85_S	0.510	0.97
52_R	373_L	0.510	0.97
45_V	428_F	0.509	0.97
113_N	127_F	0.509	0.97
152_V	155_L	0.509	0.97
78_D	374_R	0.507	0.97
72_F	75_A	0.507	0.97
363_K	379_L	0.506	0.97
151_N	155_L	0.505	0.97
329_S	343_V	0.505	0.97
111_S	266_A	0.505	0.97
409_A	424_T	0.504	0.97
205_S	209_K	0.503	0.97
229_V	237_I	0.503	0.97
20_A	318_I	0.502	0.97
90_K	93_D	0.502	0.97
407_E	432_G	0.502	0.97
181_K	217_S	0.502	0.97
124_A	289_N	0.501	0.97
165_A	250_I	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1xdiA	3	0.9735	100	0.211	Contact Map
3ladA	2	0.9868	100	0.217	Contact Map
1ojtA	2	0.9912	100	0.217	Contact Map
1lvlA	2	0.9735	100	0.221	Contact Map
1fecA	2	0.9823	100	0.223	Contact Map
2r9zA	2	0.9735	100	0.23	Contact Map
3ic9A	2	0.9956	100	0.23	Contact Map
2a8xA	2	0.9845	100	0.23	Contact Map
3o0hA	2	0.9845	100	0.23	Contact Map
2hqmA	2	0.9581	100	0.231	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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