GREMLIN Database
Q97VD7 - Uncharacterized protein
UniProt: Q97VD7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 133 (116)
Sequences: 14093 (10623)
Seq/√Len: 986.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
19_T23_E2.8171.00
35_F101_H2.6421.00
81_I104_A2.3331.00
81_I85_E2.2281.00
17_R71_S2.2121.00
79_I97_N2.1671.00
85_E89_D2.0451.00
16_A19_T2.0281.00
83_G107_E1.9261.00
82_N85_E1.9161.00
15_I19_T1.8621.00
68_E72_K1.8341.00
17_R48_I1.7911.00
83_G112_I1.7491.00
15_I24_A1.7351.00
24_A70_V1.6951.00
15_I36_A1.6761.00
69_P72_K1.6421.00
15_I38_I1.6321.00
103_L111_I1.6071.00
17_R40_D1.6041.00
37_L47_I1.5861.00
81_I90_T1.5691.00
79_I99_I1.5381.00
13_I31_Q1.5191.00
4_K83_G1.4571.00
24_A51_V1.4451.00
27_R31_Q1.4381.00
14_R39_V1.4341.00
40_D46_E1.4171.00
100_T117_L1.4151.00
82_N107_E1.4061.00
18_H71_S1.3801.00
16_A41_D1.3641.00
90_T102_L1.3521.00
24_A36_A1.3381.00
85_E93_F1.3301.00
26_E30_K1.3281.00
4_K84_E1.3161.00
93_F97_N1.3081.00
51_V56_I1.2871.00
19_T27_R1.2501.00
80_T105_I1.2471.00
40_D48_I1.2451.00
15_I70_V1.2241.00
20_S23_E1.2151.00
55_I75_I1.2021.00
79_I93_F1.1981.00
81_I102_L1.1941.00
90_T115_V1.1911.00
22_S66_Q1.1851.00
51_V70_V1.1801.00
22_S26_E1.1611.00
21_L73_V1.1591.00
23_E26_E1.1581.00
68_E73_V1.1391.00
86_D89_D1.1351.00
35_F50_I1.1331.00
92_M96_K1.1301.00
25_L56_I1.1211.00
53_R57_L1.0831.00
51_V73_V1.0801.00
13_I27_R1.0801.00
47_I111_I1.0751.00
38_I74_M1.0661.00
27_R30_K1.0651.00
34_K53_R1.0641.00
6_V87_L1.0611.00
39_V48_I1.0471.00
33_V36_A1.0291.00
6_V115_V1.0091.00
89_D93_F1.0041.00
47_I78_V0.9981.00
87_L120_V0.9831.00
22_S67_N0.9681.00
66_Q69_P0.9641.00
70_V74_M0.9631.00
95_M122_S0.9591.00
35_F100_T0.9561.00
13_I33_V0.9531.00
50_I103_L0.9491.00
53_R100_T0.9421.00
37_L111_I0.9301.00
81_I93_F0.9031.00
57_L100_T0.8861.00
47_I103_L0.8851.00
49_G74_M0.8771.00
37_L103_L0.8641.00
15_I27_R0.8631.00
58_S61_G0.8591.00
18_H69_P0.8511.00
28_M36_A0.8481.00
9_N119_D0.8441.00
84_E107_E0.8411.00
16_A39_V0.8351.00
93_F102_L0.8091.00
46_E110_K0.7851.00
71_S74_M0.7711.00
89_D92_M0.7651.00
16_A40_D0.7631.00
42_S110_K0.7591.00
101_H116_T0.7571.00
27_R36_A0.7521.00
34_K100_T0.7501.00
94_M102_L0.7501.00
100_T118_R0.7491.00
24_A28_M0.7481.00
46_E109_G0.7471.00
23_E27_R0.7341.00
105_I109_G0.7291.00
34_K117_L0.7271.00
56_I59_S0.7091.00
80_T109_G0.7071.00
101_H114_V0.6971.00
35_F114_V0.6901.00
42_S46_E0.6831.00
39_V47_I0.6761.00
7_F10_T0.6711.00
109_G112_I0.6601.00
105_I111_I0.6561.00
54_S100_T0.6511.00
71_S76_K0.6471.00
9_N12_P0.6441.00
12_P37_L0.6391.00
50_I101_H0.6281.00
118_R122_S0.6241.00
13_I36_A0.6231.00
85_E90_T0.6211.00
20_S69_P0.6141.00
6_V123_A0.6081.00
17_R41_D0.6011.00
7_F113_G0.5991.00
34_K54_S0.5981.00
119_D122_S0.5921.00
48_I74_M0.5911.00
88_I92_M0.5901.00
7_F104_A0.5871.00
53_R101_H0.5871.00
34_K37_L0.5791.00
33_V37_L0.5781.00
65_S68_E0.5771.00
35_F52_T0.5691.00
94_M117_L0.5661.00
34_K101_H0.5631.00
117_L121_L0.5601.00
91_F121_L0.5581.00
25_L53_R0.5531.00
59_S68_E0.5521.00
52_T55_I0.5511.00
95_M117_L0.5501.00
11_R31_Q0.5441.00
59_S63_G0.5431.00
82_N105_I0.5411.00
50_I75_I0.5381.00
78_V103_L0.5381.00
98_N118_R0.5371.00
29_D53_R0.5321.00
21_L59_S0.5321.00
82_N109_G0.5311.00
115_V120_V0.5301.00
50_I78_V0.5261.00
90_T94_M0.5261.00
21_L70_V0.5251.00
14_R36_A0.5201.00
37_L48_I0.5191.00
9_N114_V0.5141.00
37_L114_V0.5121.00
25_L51_V0.5121.00
7_F112_I0.5031.00
75_I79_I0.5021.00
25_L29_D0.5021.00
57_L61_G0.5021.00
91_F95_M0.5011.00
12_P33_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l2bA 2 0.8647 99.9 0.203 Contact Map
3pc3A 2 0.9398 99.8 0.243 Contact Map
4cooA 2 0.9248 99.8 0.243 Contact Map
1pvmA 2 0.9774 99.8 0.247 Contact Map
3ocoA 2 0.9098 99.8 0.248 Contact Map
3fhmA 2 0.9248 99.8 0.249 Contact Map
3orgA 2 0.8647 99.8 0.249 Contact Map
3lfrA 2 0.9474 99.8 0.256 Contact Map
2qrdG 1 0.9474 99.8 0.26 Contact Map
2yziA 2 0.9699 99.8 0.261 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.