Q97VC8 - SULSO - GREMLIN Contacts

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Q97VC8 - Permease, multidrug efflux

UniProt:	Q97VC8	Sequences: MVQYKWIALSNTSLGAFMGFMNANVVLIALPAIFRGININPFNSFQYLLWILFGYSIVSAILVVNVGRISDIFGRVRMYNLGFLIFTIASILLYLTPGKGDIAAIQLIIYRILQGIGGSFLMANSAAILSEAFPPNERGFALGLNGVIGIFGGVAGIIIGGILASIYWRDVFLVSVPIGILGTIWSYKSLRQLNKPNRNQSIDIVGNILYAVSLISILLGITYGILPYGNQVTGWTNPFVISGIVAGVGMFIGFLFVESRVKDPMFRIELFKIRAFTSSAVSIILAQLAFGGLQLMLVLLLQAIWLPLHGYSYEVTPFWAGVYLLPLLAGFGIMGSIAGRLADRYGARSLATIGLLIMGIGVLTLTTLPYNFNYIEFAVIIFFIGVGNGLFVSPNMTALMNASPPQHRGSASGIRAMLTNTGSTLSIGIFFTIVIDTLYISLPPVLTNALTAAGAPQLAPILSKIPPTAAIFASFLGYNPVSTILSQLPTSLVNAIPASTIATITGTYWFPNVIASPFMEALRIAFYVSASMAFLATIASALRGKTVIYERDLMRPMAVNSSDDKKD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	567 (434)
Sequences:	10993 (8281)
Seq/√Len:	397.5

ECOLI - EMRB EMRY MDTD HSRA
BACSU - YHCA YUSP BMR3 YFIU YUBD LMRB YCNB
SULSO - Q97VC8 Q97YH0 Q97U91 Q97Y15 Q97WR9 Q97X47 Q97VB9 Q97YY8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
97_P	106_Q	5.400	1.00
87_T	179_G	5.394	1.00
85_I	117_G	4.122	1.00
213_S	251_F	3.826	1.00
209_L	257_V	3.545	1.00
94_Y	173_L	3.407	1.00
105_I	109_I	3.234	1.00
217_I	247_G	3.170	1.00
54_G	112_I	3.057	1.00
92_L	110_Y	2.991	1.00
403_S	411_A	2.918	1.00
5_K	137_E	2.893	1.00
364_T	380_I	2.790	1.00
98_G	106_Q	2.752	1.00
220_G	244_I	2.741	1.00
269_E	407_H	2.734	1.00
212_V	250_M	2.702	1.00
98_G	105_I	2.700	1.00
334_M	386_V	2.665	1.00
62_L	116_I	2.585	1.00
205_V	257_V	2.544	1.00
186_S	190_L	2.459	1.00
80_N	183_T	2.413	1.00
166_I	170_D	2.346	1.00
316_T	319_W	2.341	1.00
241_I	245_V	2.311	1.00
330_G	382_F	2.234	1.00
203_D	206_G	2.202	1.00
252_I	256_F	2.173	1.00
80_N	187_Y	2.172	1.00
224_G	235_W	2.127	1.00
89_A	113_L	2.113	1.00
93_L	110_Y	2.078	1.00
15_G	79_Y	2.076	1.00
361_G	384_I	2.066	1.00
75_R	131_E	2.050	1.00
440_I	444_P	2.049	1.00
137_E	140_F	2.025	1.00
163_L	170_D	2.007	1.00
80_N	186_S	1.996	1.00
89_A	117_G	1.988	1.00
271_F	277_T	1.986	1.00
267_R	407_H	1.960	1.00
261_V	264_P	1.909	1.00
184_I	188_K	1.904	1.00
82_G	120_F	1.846	1.00
404_P	407_H	1.843	1.00
255_L	259_S	1.838	1.00
39_I	104_A	1.836	1.00
58_V	112_I	1.786	1.00
71_D	409_G	1.776	1.00
254_F	258_E	1.775	1.00
204_I	208_I	1.769	1.00
8_A	132_A	1.755	1.00
90_S	175_S	1.749	1.00
291_G	423_S	1.729	1.00
167_Y	170_D	1.714	1.00
66_V	120_F	1.708	1.00
213_S	247_G	1.702	1.00
47_Y	104_A	1.697	1.00
40_N	47_Y	1.670	1.00
29_A	164_A	1.647	1.00
246_A	250_M	1.647	1.00
77_R	192_Q	1.647	1.00
91_I	95_L	1.646	1.00
216_S	250_M	1.638	1.00
17_F	152_G	1.632	1.00
106_Q	110_Y	1.627	1.00
165_S	318_F	1.606	1.00
39_I	47_Y	1.601	1.00
255_L	268_I	1.596	1.00
22_N	25_V	1.589	1.00
302_Q	320_A	1.586	1.00
288_L	426_S	1.585	1.00
340_R	344_R	1.554	1.00
223_Y	233_T	1.552	1.00
216_S	243_G	1.539	1.00
104_A	108_I	1.527	1.00
357_I	387_G	1.526	1.00
300_L	309_H	1.520	1.00
13_S	148_I	1.504	1.00
13_S	144_L	1.489	1.00
84_L	183_T	1.487	1.00
201_S	263_D	1.480	1.00
22_N	175_S	1.474	1.00
242_S	246_A	1.461	1.00
93_L	107_L	1.450	1.00
89_A	110_Y	1.445	1.00
277_T	281_V	1.445	1.00
259_S	269_E	1.443	1.00
213_S	250_M	1.424	1.00
267_R	410_S	1.419	1.00
96_T	106_Q	1.415	1.00
247_G	251_F	1.413	1.00
216_S	246_A	1.412	1.00
76_V	80_N	1.410	1.00
256_F	259_S	1.410	1.00
339_G	343_D	1.406	1.00
444_P	447_T	1.405	1.00
130_S	138_R	1.400	1.00
319_W	322_V	1.395	1.00
220_G	247_G	1.394	1.00
361_G	387_G	1.390	1.00
55_Y	118_G	1.390	1.00
373_N	376_E	1.389	1.00
133_F	141_A	1.383	1.00
361_G	380_I	1.373	1.00
139_G	343_D	1.372	1.00
346_G	349_S	1.364	1.00
284_I	422_G	1.353	1.00
441_S	445_V	1.352	1.00
354_G	391_F	1.346	1.00
29_A	171_V	1.340	1.00
356_L	360_I	1.339	1.00
134_P	137_E	1.337	1.00
92_L	106_Q	1.335	1.00
374_Y	378_A	1.335	1.00
349_S	352_T	1.323	1.00
292_G	430_F	1.317	1.00
11_N	185_W	1.316	1.00
334_M	389_G	1.314	1.00
68_R	72_I	1.310	1.00
75_R	192_Q	1.304	1.00
11_N	189_S	1.300	1.00
96_T	110_Y	1.294	1.00
76_V	187_Y	1.292	1.00
257_V	261_V	1.292	1.00
368_L	372_F	1.286	1.00
25_V	174_V	1.284	1.00
323_Y	374_Y	1.279	1.00
253_G	256_F	1.278	1.00
83_F	182_G	1.274	1.00
81_L	85_I	1.269	1.00
363_L	366_T	1.268	1.00
62_L	119_S	1.266	1.00
135_P	138_R	1.259	1.00
70_S	75_R	1.253	1.00
348_R	352_T	1.253	1.00
301_L	323_Y	1.252	1.00
244_I	248_V	1.252	1.00
330_G	334_M	1.247	1.00
206_G	257_V	1.245	1.00
359_G	363_L	1.230	1.00
125_S	145_N	1.230	1.00
220_G	240_V	1.228	1.00
176_V	180_I	1.228	1.00
20_F	149_G	1.226	1.00
64_V	210_Y	1.215	1.00
369_P	372_F	1.213	1.00
266_F	414_I	1.213	1.00
32_A	35_R	1.209	1.00
165_S	316_T	1.205	1.00
14_L	182_G	1.205	1.00
161_G	317_P	1.204	1.00
361_G	383_F	1.192	1.00
212_V	216_S	1.192	1.00
340_R	343_D	1.184	1.00
209_L	253_G	1.181	1.00
235_W	240_V	1.180	1.00
183_T	187_Y	1.179	1.00
95_L	173_L	1.178	1.00
79_Y	186_S	1.178	1.00
23_A	56_S	1.171	1.00
327_L	385_G	1.170	1.00
185_W	189_S	1.169	1.00
159_I	162_I	1.167	1.00
231_Q	234_G	1.163	1.00
375_I	379_V	1.161	1.00
88_I	92_L	1.161	1.00
69_I	73_F	1.161	1.00
311_Y	323_Y	1.160	1.00
61_I	211_A	1.159	1.00
34_F	48_L	1.157	1.00
201_S	262_K	1.151	1.00
334_M	390_L	1.146	1.00
9_L	133_F	1.145	1.00
273_I	277_T	1.142	1.00
319_W	323_Y	1.135	1.00
256_F	260_R	1.130	1.00
458_L	461_I	1.123	1.00
89_A	92_L	1.119	1.00
236_T	241_I	1.118	1.00
353_I	390_L	1.112	1.00
65_N	207_N	1.104	1.00
367_T	380_I	1.100	1.00
69_I	78_M	1.098	1.00
18_M	179_G	1.097	1.00
238_P	242_S	1.096	1.00
441_S	444_P	1.095	1.00
136_N	140_F	1.094	1.00
180_I	184_I	1.093	1.00
329_A	333_I	1.086	1.00
376_E	379_V	1.085	1.00
219_L	223_Y	1.085	1.00
280_A	418_L	1.078	1.00
67_G	71_D	1.077	1.00
53_F	222_T	1.074	1.00
97_P	104_A	1.071	1.00
223_Y	232_V	1.068	1.00
375_I	378_A	1.066	1.00
279_S	399_L	1.065	1.00
206_G	261_V	1.064	1.00
233_T	239_F	1.064	1.00
444_P	450_L	1.062	1.00
446_L	449_A	1.061	1.00
58_V	115_G	1.061	1.00
30_L	48_L	1.060	1.00
54_G	58_V	1.059	1.00
25_V	171_V	1.054	1.00
252_I	255_L	1.053	1.00
447_T	450_L	1.053	1.00
341_L	345_Y	1.051	1.00
93_L	172_F	1.048	1.00
91_I	176_V	1.032	1.00
233_T	240_V	1.031	1.00
27_L	52_L	1.029	1.00
54_G	108_I	1.029	1.00
71_D	75_R	1.029	1.00
442_L	445_V	1.017	1.00
257_V	260_R	1.014	1.00
214_L	421_T	1.012	1.00
220_G	243_G	1.012	1.00
311_Y	319_W	1.012	1.00
363_L	367_T	1.011	1.00
87_T	183_T	1.010	1.00
442_L	446_L	0.997	1.00
22_N	174_V	0.992	1.00
349_S	353_I	0.989	1.00
251_F	255_L	0.988	1.00
130_S	408_R	0.986	1.00
97_P	105_I	0.986	1.00
221_I	224_G	0.984	1.00
354_G	387_G	0.979	1.00
336_S	340_R	0.977	1.00
442_L	449_A	0.973	1.00
452_A	456_P	0.968	1.00
162_I	318_F	0.964	1.00
445_V	448_N	0.964	1.00
18_M	175_S	0.963	1.00
274_R	277_T	0.962	1.00
209_L	250_M	0.958	1.00
337_I	340_R	0.958	1.00
92_L	113_L	0.958	1.00
345_Y	350_L	0.956	1.00
143_G	147_V	0.956	1.00
105_I	108_I	0.956	1.00
70_S	124_N	0.955	1.00
78_M	120_F	0.955	1.00
445_V	449_A	0.948	1.00
188_K	191_R	0.947	1.00
355_L	391_F	0.946	1.00
51_I	107_L	0.946	1.00
206_G	258_E	0.945	1.00
218_L	424_T	0.944	1.00
25_V	160_G	0.943	1.00
354_G	361_G	0.941	1.00
75_R	193_L	0.937	1.00
6_W	10_S	0.933	1.00
237_N	241_I	0.930	1.00
87_T	91_I	0.929	1.00
92_L	95_L	0.921	1.00
5_K	133_F	0.919	1.00
379_V	382_F	0.919	1.00
80_N	84_L	0.918	1.00
444_P	448_N	0.911	1.00
354_G	390_L	0.911	1.00
207_N	265_M	0.909	1.00
296_M	431_F	0.907	1.00
274_R	278_S	0.907	1.00
61_I	215_I	0.906	1.00
378_A	382_F	0.906	1.00
212_V	246_A	0.905	1.00
345_Y	349_S	0.902	1.00
58_V	62_L	0.901	1.00
73_F	78_M	0.897	1.00
379_V	383_F	0.896	1.00
248_V	252_I	0.895	1.00
437_T	441_S	0.891	1.00
200_Q	263_D	0.889	1.00
76_V	192_Q	0.889	1.00
7_I	189_S	0.889	1.00
185_W	188_K	0.886	1.00
376_E	380_I	0.886	1.00
18_M	83_F	0.883	1.00
95_L	110_Y	0.878	1.00
32_A	36_G	0.872	1.00
220_G	224_G	0.868	1.00
396_M	415_R	0.867	1.00
139_G	339_G	0.863	1.00
440_I	449_A	0.862	1.00
334_M	338_A	0.860	1.00
239_F	243_G	0.858	1.00
342_A	394_P	0.857	1.00
276_F	411_A	0.851	1.00
237_N	240_V	0.851	1.00
208_I	212_V	0.850	1.00
129_L	145_N	0.849	1.00
253_G	257_V	0.849	1.00
456_P	460_P	0.846	1.00
457_Q	461_I	0.845	1.00
224_G	240_V	0.843	1.00
109_I	112_I	0.842	1.00
272_K	277_T	0.841	1.00
71_D	410_S	0.836	1.00
275_A	402_A	0.834	1.00
85_I	89_A	0.833	1.00
341_L	350_L	0.830	1.00
269_E	272_K	0.825	1.00
301_L	309_H	0.825	1.00
286_A	391_F	0.824	1.00
302_Q	317_P	0.824	1.00
259_S	272_K	0.823	1.00
142_L	146_G	0.823	1.00
239_F	242_S	0.822	1.00
74_G	77_R	0.819	1.00
142_L	397_T	0.819	1.00
271_F	276_F	0.817	1.00
399_L	415_R	0.813	1.00
443_P	447_T	0.812	1.00
298_V	320_A	0.812	1.00
346_G	350_L	0.809	1.00
447_T	456_P	0.808	1.00
400_M	412_S	0.806	1.00
444_P	449_A	0.805	1.00
276_F	280_A	0.800	1.00
449_A	453_A	0.800	1.00
358_M	387_G	0.800	1.00
126_A	145_N	0.800	1.00
432_T	436_D	0.800	1.00
192_Q	195_K	0.795	1.00
29_A	33_I	0.795	1.00
327_L	384_I	0.792	1.00
47_Y	105_I	0.790	1.00
73_F	202_I	0.789	1.00
11_N	182_G	0.789	1.00
365_L	368_L	0.784	1.00
33_I	164_A	0.781	1.00
450_L	455_A	0.781	1.00
233_T	237_N	0.781	1.00
231_Q	235_W	0.781	1.00
81_L	84_L	0.777	1.00
213_S	255_L	0.774	1.00
51_I	104_A	0.774	1.00
177_P	180_I	0.774	1.00
19_G	121_L	0.773	1.00
26_V	51_I	0.773	1.00
210_Y	214_L	0.772	1.00
444_P	452_A	0.771	1.00
40_N	46_Q	0.768	1.00
78_M	81_L	0.768	1.00
136_N	139_G	0.767	1.00
84_L	88_I	0.766	1.00
205_V	261_V	0.766	1.00
55_Y	86_F	0.764	1.00
248_V	251_F	0.762	1.00
447_T	452_A	0.761	1.00
350_L	353_I	0.761	1.00
335_G	339_G	0.761	1.00
356_L	359_G	0.759	1.00
16_A	149_G	0.759	1.00
52_L	295_L	0.758	1.00
450_L	454_G	0.754	1.00
372_F	376_E	0.753	1.00
56_S	424_T	0.753	1.00
146_G	150_I	0.752	1.00
449_A	455_A	0.751	1.00
311_Y	374_Y	0.751	1.00
170_D	177_P	0.750	1.00
258_E	261_V	0.750	1.00
212_V	215_I	0.749	1.00
397_T	401_N	0.748	1.00
244_I	247_G	0.748	1.00
334_M	337_I	0.748	1.00
301_L	377_F	0.746	1.00
440_I	446_L	0.742	1.00
280_A	414_I	0.741	1.00
284_I	425_L	0.740	1.00
278_S	282_S	0.738	1.00
169_R	173_L	0.730	1.00
275_A	398_A	0.728	1.00
191_R	194_N	0.727	1.00
202_I	207_N	0.726	1.00
441_S	447_T	0.726	1.00
12_T	125_S	0.726	1.00
143_G	335_G	0.726	1.00
390_L	394_P	0.726	1.00
152_G	157_I	0.726	1.00
110_Y	113_L	0.725	1.00
165_S	317_P	0.724	1.00
210_Y	254_F	0.723	1.00
385_G	389_G	0.721	1.00
194_N	197_N	0.721	1.00
97_P	110_Y	0.720	1.00
273_I	404_P	0.718	1.00
56_S	423_S	0.717	1.00
336_S	339_G	0.716	1.00
283_I	395_N	0.716	1.00
458_L	462_L	0.715	1.00
87_T	176_V	0.715	1.00
33_I	107_L	0.714	1.00
259_S	268_I	0.712	1.00
129_L	141_A	0.709	1.00
282_S	355_L	0.709	1.00
58_V	117_G	0.706	1.00
440_I	452_A	0.706	1.00
21_M	25_V	0.706	1.00
246_A	253_G	0.706	1.00
299_L	303_A	0.705	1.00
67_G	413_G	0.704	1.00
211_A	215_I	0.704	1.00
76_V	191_R	0.702	1.00
364_T	367_T	0.702	1.00
70_S	409_G	0.702	1.00
39_I	108_I	0.701	1.00
98_G	104_A	0.695	1.00
273_I	407_H	0.695	1.00
60_A	421_T	0.694	1.00
240_V	243_G	0.693	1.00
352_T	359_G	0.693	1.00
162_I	166_I	0.693	1.00
223_Y	240_V	0.692	1.00
326_P	330_G	0.692	1.00
304_I	309_H	0.690	1.00
282_S	395_N	0.686	0.99
139_G	143_G	0.686	0.99
173_L	177_P	0.684	0.99
422_G	426_S	0.682	0.99
70_S	127_A	0.681	0.99
322_V	325_L	0.681	0.99
184_I	187_Y	0.680	0.99
342_A	350_L	0.679	0.99
293_L	384_I	0.678	0.99
255_L	271_F	0.676	0.99
209_L	254_F	0.675	0.99
163_L	174_V	0.674	0.99
83_F	183_T	0.671	0.99
129_L	132_A	0.671	0.99
205_V	209_L	0.670	0.99
457_Q	460_P	0.669	0.99
338_A	390_L	0.669	0.99
451_T	456_P	0.669	0.99
22_N	90_S	0.667	0.99
109_I	113_L	0.667	0.99
367_T	376_E	0.666	0.99
297_L	381_I	0.665	0.99
333_I	336_S	0.662	0.99
152_G	156_G	0.661	0.99
91_I	173_L	0.661	0.99
160_G	164_A	0.660	0.99
245_V	249_G	0.660	0.99
77_R	81_L	0.660	0.99
78_M	124_N	0.659	0.99
446_L	450_L	0.659	0.99
352_T	356_L	0.658	0.99
22_N	177_P	0.658	0.99
254_F	266_F	0.658	0.99
135_P	139_G	0.658	0.99
9_L	141_A	0.657	0.99
223_Y	239_F	0.656	0.99
366_T	369_P	0.656	0.99
210_Y	265_M	0.655	0.99
338_A	389_G	0.653	0.99
163_L	166_I	0.653	0.99
127_A	409_G	0.652	0.99
128_I	132_A	0.651	0.99
93_L	114_Q	0.650	0.99
362_V	384_I	0.649	0.99
455_A	460_P	0.649	0.99
82_G	117_G	0.648	0.99
66_V	123_A	0.648	0.99
48_L	299_L	0.648	0.99
351_A	398_A	0.647	0.99
357_I	383_F	0.647	0.99
67_G	124_N	0.644	0.99
6_W	140_F	0.643	0.99
22_N	55_Y	0.641	0.99
450_L	456_P	0.641	0.99
93_L	96_T	0.639	0.99
276_F	399_L	0.639	0.99
40_N	45_F	0.639	0.99
181_L	185_W	0.638	0.99
273_I	402_A	0.638	0.99
193_L	196_P	0.637	0.99
71_D	74_G	0.636	0.99
196_P	199_N	0.635	0.99
283_I	415_R	0.635	0.99
354_G	394_P	0.633	0.99
323_Y	326_P	0.633	0.99
364_T	379_V	0.631	0.99
442_L	447_T	0.630	0.99
50_W	54_G	0.629	0.99
12_T	132_A	0.627	0.99
150_I	331_F	0.627	0.99
360_I	363_L	0.627	0.99
213_S	216_S	0.626	0.99
126_A	412_S	0.626	0.99
443_P	453_A	0.625	0.99
184_I	189_S	0.625	0.99
360_I	364_T	0.625	0.99
11_N	186_S	0.625	0.99
33_I	37_I	0.623	0.99
382_F	386_V	0.623	0.99
452_A	455_A	0.621	0.99
214_L	417_M	0.621	0.99
295_L	427_I	0.620	0.99
72_I	201_S	0.620	0.99
362_V	366_T	0.618	0.99
147_V	151_F	0.618	0.99
207_N	211_A	0.618	0.99
456_P	459_A	0.618	0.99
53_F	431_F	0.617	0.99
368_L	380_I	0.616	0.99
440_I	445_V	0.616	0.99
447_T	451_T	0.615	0.99
28_I	320_A	0.615	0.99
216_S	247_G	0.614	0.99
83_F	186_S	0.613	0.99
131_E	408_R	0.613	0.99
45_F	49_L	0.610	0.99
155_A	159_I	0.609	0.99
452_A	460_P	0.608	0.99
75_R	127_A	0.608	0.99
236_T	239_F	0.605	0.99
161_G	321_G	0.605	0.99
149_G	153_G	0.605	0.99
249_G	253_G	0.604	0.99
451_T	460_P	0.602	0.99
127_A	412_S	0.601	0.99
456_P	461_I	0.600	0.99
447_T	453_A	0.600	0.99
22_N	26_V	0.597	0.99
438_L	442_L	0.597	0.99
219_L	243_G	0.596	0.99
195_K	199_N	0.596	0.99
37_I	104_A	0.596	0.99
24_N	157_I	0.595	0.99
429_I	432_T	0.594	0.99
443_P	446_L	0.593	0.99
30_L	52_L	0.593	0.99
24_N	153_G	0.592	0.99
106_Q	109_I	0.591	0.99
440_I	448_N	0.590	0.98
298_V	324_L	0.588	0.98
351_A	395_N	0.585	0.98
284_I	418_L	0.584	0.98
154_V	328_L	0.584	0.98
140_F	143_G	0.584	0.98
337_I	341_L	0.583	0.98
59_S	420_N	0.583	0.98
442_L	448_N	0.582	0.98
55_Y	111_R	0.582	0.98
286_A	395_N	0.580	0.98
15_G	121_L	0.579	0.98
446_L	452_A	0.578	0.98
440_I	443_P	0.576	0.98
34_F	39_I	0.574	0.98
57_I	215_I	0.573	0.98
358_M	384_I	0.573	0.98
286_A	290_F	0.573	0.98
441_S	446_L	0.573	0.98
111_R	114_Q	0.572	0.98
364_T	383_F	0.572	0.98
342_A	397_T	0.571	0.98
97_P	169_R	0.569	0.98
242_S	245_V	0.565	0.98
20_F	153_G	0.564	0.98
329_A	332_G	0.563	0.98
86_F	160_G	0.562	0.98
50_W	57_I	0.562	0.98
259_S	262_K	0.561	0.98
353_I	357_I	0.560	0.98
86_F	118_G	0.558	0.98
130_S	400_M	0.558	0.98
187_Y	191_R	0.557	0.98
325_L	328_L	0.557	0.98
85_I	113_L	0.555	0.98
454_G	458_L	0.555	0.98
451_T	455_A	0.554	0.98
204_I	207_N	0.552	0.98
67_G	409_G	0.551	0.98
437_T	440_I	0.549	0.98
287_Q	419_T	0.549	0.98
330_G	333_I	0.548	0.98
240_V	244_I	0.547	0.98
140_F	340_R	0.547	0.98
442_L	453_A	0.546	0.98
83_F	179_G	0.546	0.98
22_N	111_R	0.545	0.97
290_F	392_V	0.543	0.97
440_I	450_L	0.541	0.97
290_F	388_N	0.540	0.97
275_A	278_S	0.540	0.97
448_N	455_A	0.540	0.97
19_G	122_M	0.536	0.97
147_V	150_I	0.535	0.97
447_T	454_G	0.535	0.97
296_M	434_V	0.535	0.97
63_V	417_M	0.534	0.97
454_G	460_P	0.534	0.97
63_V	416_A	0.534	0.97
209_L	213_S	0.534	0.97
301_L	311_Y	0.532	0.97
175_S	179_G	0.532	0.97
61_I	207_N	0.532	0.97
140_F	144_L	0.531	0.97
355_L	359_G	0.529	0.97
60_A	424_T	0.527	0.97
300_L	304_I	0.526	0.97
17_F	148_I	0.526	0.97
441_S	458_L	0.526	0.97
27_L	295_L	0.526	0.97
86_F	111_R	0.525	0.97
59_S	118_G	0.525	0.97
56_S	420_N	0.525	0.97
453_A	457_Q	0.524	0.97
451_T	457_Q	0.524	0.97
150_I	335_G	0.524	0.97
311_Y	316_T	0.523	0.97
115_G	119_S	0.519	0.97
330_G	378_A	0.519	0.97
454_G	459_A	0.517	0.97
146_G	335_G	0.516	0.97
33_I	48_L	0.516	0.97
9_L	129_L	0.516	0.97
131_E	193_L	0.516	0.97
8_A	11_N	0.516	0.97
203_D	257_V	0.514	0.96
16_A	125_S	0.513	0.96
453_A	456_P	0.511	0.96
433_I	437_T	0.511	0.96
192_Q	196_P	0.510	0.96
27_L	30_L	0.509	0.96
39_I	48_L	0.509	0.96
17_F	155_A	0.508	0.96
396_M	400_M	0.506	0.96
217_I	251_F	0.506	0.96
58_V	116_I	0.505	0.96
224_G	233_T	0.505	0.96
268_I	271_F	0.504	0.96
413_G	417_M	0.504	0.96
280_A	415_R	0.504	0.96
66_V	119_S	0.503	0.96
130_S	142_L	0.503	0.96
153_G	291_G	0.503	0.96
206_G	254_F	0.503	0.96
450_L	458_L	0.503	0.96
156_G	160_G	0.502	0.96
455_A	459_A	0.502	0.96
408_R	412_S	0.501	0.96
181_L	184_I	0.500	0.96
115_G	413_G	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pw4A	1	0.716	100	0.566	Contact Map
3wdoA	1	0.7831	100	0.57	Contact Map
4j05A	3	0.6808	100	0.573	Contact Map
4pypA	1	0.7372	100	0.577	Contact Map
2gfpA	2	0.6596	100	0.587	Contact Map
4zw9A	1	0.7619	100	0.589	Contact Map
4gc0A	1	0.7584	100	0.589	Contact Map
4ldsA	2	0.7213	100	0.599	Contact Map
4w6vA	1	0.7619	100	0.6	Contact Map
2cfqA	1	0.7178	100	0.603	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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