Q97VC0 - SULSO - GREMLIN Contacts

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Q97VC0 - ABC transporter, permease

UniProt:	Q97VC0	Sequences: MIKYSVPYLVYIAVFGIIPLILTFVIVGINFSGAIKSSFSVAPPPEIIYNTFFFSLFTAVVSTLLGYILAITVDIYPKKLLILLILLPFTIPFTASALIWVISFYGGYGWFTYFLGINYDPLYFSKSALFAVSLVSAWSSVPLAFLLILASLKSIPKEIKESSQIDGLTLSQYYFKVAFPYSLKGILLAFLITFVLSMGNFDLPYVMTQGGPGFSTTTLPLIVYFMMFQYDNFSGGALFASILALIASIPAIGVALLVKSKGFRFSLPAIKIPDKIFKIIALLISLIIIIFLDFPVYWMVLVATRPNTLDFLKPPVLIPKEFTLSYLVSSLESSVPYIISSIIVSLIVGVLTILLSSLGAYEGARKFWFWLLLLSIYLYALPSTSYIIPVYLMTSDLHLINTWIGLALPSAIFTASFAFWTMFNFYIDFPKVYEEAAEIDGMKNKILKLILPLSRPFLIATFVISFTFAWHLLFYPLVLSETPYQMNFPPTGSETATIFALNAISQGSVNWALLASSALVASLPVVIVSYVAQDYMLRGLYSGGVKGA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	548 (488)
Sequences:	3220 (2477)
Seq/√Len:	112.1

ECOLI - THIP YNJC
HALSA - Q9HMT4 Q9HR05
SULSO - Q97VC0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
303_A	327_L	6.078	1.00
437_A	445_K	5.771	1.00
165_I	439_I	4.264	1.00
61_V	137_A	4.051	1.00
163_S	173_Y	4.041	1.00
444_N	447_L	3.857	1.00
57_F	133_S	3.640	1.00
27_V	35_I	3.393	1.00
367_F	370_W	3.342	1.00
171_S	175_F	3.292	1.00
172_Q	176_K	3.273	1.00
425_F	457_F	3.110	1.00
509_V	513_L	2.936	1.00
339_I	343_I	2.912	1.00
341_S	470_W	2.800	1.00
518_A	521_A	2.799	1.00
509_V	518_A	2.795	1.00
444_N	448_K	2.780	1.00
57_F	129_L	2.762	1.00
442_M	448_K	2.725	1.00
325_S	328_V	2.720	1.00
350_V	462_F	2.703	1.00
512_A	515_A	2.646	1.00
66_G	144_A	2.646	1.00
166_D	440_D	2.621	1.00
351_L	411_A	2.617	1.00
59_A	190_F	2.590	1.00
274_D	278_K	2.478	1.00
49_Y	53_F	2.469	1.00
169_T	172_Q	2.425	1.00
509_V	515_A	2.415	1.00
366_K	370_W	2.331	1.00
515_A	518_A	2.314	1.00
349_G	462_F	2.311	1.00
274_D	280_I	2.306	1.00
273_P	276_I	2.276	1.00
517_S	521_A	2.249	1.00
63_T	190_F	2.219	1.00
509_V	517_S	2.188	1.00
163_S	177_V	2.138	1.00
508_S	514_L	2.127	1.00
347_I	407_A	2.123	1.00
511_W	518_A	2.118	1.00
515_A	521_A	2.069	1.00
252_I	256_L	2.050	1.00
168_L	176_K	2.044	1.00
323_T	326_Y	2.042	1.00
144_A	148_I	2.027	1.00
508_S	512_A	2.025	1.00
278_K	282_L	2.021	1.00
80_L	84_L	2.016	1.00
172_Q	175_F	1.997	1.00
129_L	133_S	1.981	1.00
161_E	435_E	1.975	1.00
299_M	303_A	1.968	1.00
273_P	277_F	1.959	1.00
273_P	279_I	1.957	1.00
53_F	129_L	1.952	1.00
343_I	347_I	1.939	1.00
295_P	299_M	1.910	1.00
509_V	516_S	1.905	1.00
509_V	512_A	1.904	1.00
510_N	515_A	1.896	1.00
508_S	511_W	1.894	1.00
300_V	303_A	1.881	1.00
511_W	517_S	1.874	1.00
280_I	284_I	1.868	1.00
511_W	521_A	1.831	1.00
67_Y	182_S	1.825	1.00
511_W	514_L	1.822	1.00
348_V	469_A	1.806	1.00
67_Y	148_I	1.784	1.00
176_K	448_K	1.773	1.00
511_W	515_A	1.770	1.00
55_S	194_F	1.769	1.00
201_F	224_Y	1.748	1.00
47_I	222_I	1.745	1.00
508_S	515_A	1.724	1.00
280_I	283_L	1.712	1.00
167_G	441_G	1.711	1.00
160_K	178_A	1.707	1.00
162_S	436_A	1.689	1.00
360_A	426_Y	1.684	1.00
509_V	514_L	1.675	1.00
513_L	517_S	1.650	1.00
524_P	528_V	1.646	1.00
144_A	193_T	1.640	1.00
168_L	442_M	1.636	1.00
301_L	305_R	1.634	1.00
274_D	277_F	1.631	1.00
287_I	291_F	1.631	1.00
46_E	49_Y	1.631	1.00
144_A	189_A	1.624	1.00
511_W	516_S	1.612	1.00
525_V	528_V	1.610	1.00
256_L	259_K	1.606	1.00
151_S	185_G	1.598	1.00
521_A	525_V	1.568	1.00
513_L	519_L	1.551	1.00
513_L	518_A	1.551	1.00
514_L	517_S	1.550	1.00
437_A	442_M	1.549	1.00
54_F	129_L	1.537	1.00
509_V	519_L	1.532	1.00
164_Q	173_Y	1.521	1.00
345_S	470_W	1.514	1.00
345_S	349_G	1.506	1.00
288_I	291_F	1.477	1.00
346_L	350_V	1.475	1.00
13_A	17_I	1.468	1.00
27_V	241_S	1.466	1.00
280_I	295_P	1.450	1.00
62_S	137_A	1.441	1.00
523_L	526_V	1.441	1.00
510_N	513_L	1.437	1.00
129_L	216_T	1.420	1.00
274_D	295_P	1.408	1.00
499_F	502_N	1.404	1.00
277_F	281_A	1.401	1.00
344_V	407_A	1.399	1.00
23_T	389_P	1.397	1.00
343_I	346_L	1.385	1.00
73_V	145_F	1.383	1.00
182_S	185_G	1.379	1.00
291_F	295_P	1.379	1.00
125_S	128_A	1.378	1.00
352_T	411_A	1.375	1.00
245_L	249_I	1.373	1.00
66_G	148_I	1.370	1.00
289_I	293_D	1.365	1.00
288_I	292_L	1.360	1.00
249_I	253_G	1.359	1.00
509_V	521_A	1.351	1.00
521_A	524_P	1.350	1.00
510_N	518_A	1.347	1.00
409_P	475_Y	1.343	1.00
511_W	519_L	1.339	1.00
61_V	133_S	1.336	1.00
429_F	454_S	1.324	1.00
168_L	172_Q	1.321	1.00
119_Y	122_L	1.318	1.00
290_I	295_P	1.311	1.00
53_F	57_F	1.311	1.00
265_F	268_P	1.304	0.99
18_I	393_M	1.280	0.99
437_A	449_L	1.275	0.99
295_P	301_L	1.270	0.99
357_S	458_L	1.266	0.99
303_A	306_P	1.254	0.99
516_S	521_A	1.251	0.99
292_L	303_A	1.244	0.99
518_A	525_V	1.244	0.99
512_A	519_L	1.243	0.99
298_W	302_V	1.237	0.99
512_A	521_A	1.233	0.99
57_F	137_A	1.228	0.99
164_Q	438_E	1.222	0.99
280_I	287_I	1.222	0.99
71_I	174_Y	1.217	0.99
130_F	134_L	1.215	0.99
64_L	68_I	1.211	0.99
276_I	279_I	1.209	0.99
170_L	173_Y	1.206	0.99
50_N	216_T	1.205	0.99
513_L	516_S	1.201	0.99
372_L	420_W	1.196	0.99
45_P	49_Y	1.195	0.99
422_M	461_T	1.194	0.99
305_R	308_T	1.191	0.99
476_P	487_N	1.191	0.99
510_N	521_A	1.190	0.99
82_I	145_F	1.184	0.99
293_D	297_Y	1.183	0.99
278_K	281_A	1.181	0.99
133_S	137_A	1.176	0.99
35_I	241_S	1.174	0.99
295_P	308_T	1.168	0.99
512_A	516_S	1.167	0.99
445_K	449_L	1.166	0.99
19_P	24_F	1.164	0.99
434_E	450_I	1.162	0.99
67_Y	186_I	1.149	0.99
284_I	287_I	1.148	0.99
335_V	339_I	1.147	0.99
365_R	434_E	1.146	0.99
340_S	484_Y	1.145	0.99
116_G	120_D	1.145	0.99
108_Y	112_T	1.138	0.99
267_L	270_I	1.132	0.99
295_P	302_V	1.130	0.99
344_V	406_L	1.129	0.99
510_N	517_S	1.126	0.98
148_I	186_I	1.124	0.98
324_L	328_V	1.122	0.98
516_S	520_V	1.110	0.98
410_S	476_P	1.107	0.98
356_S	418_A	1.106	0.98
100_W	135_V	1.104	0.98
433_Y	453_L	1.098	0.98
292_L	295_P	1.098	0.98
281_A	285_S	1.096	0.98
303_A	308_T	1.088	0.98
518_A	522_S	1.088	0.98
232_N	235_G	1.088	0.98
118_N	122_L	1.086	0.98
160_K	173_Y	1.085	0.98
292_L	299_M	1.072	0.98
508_S	513_L	1.071	0.98
410_S	469_A	1.071	0.98
472_L	476_P	1.068	0.98
437_A	448_K	1.064	0.98
303_A	307_N	1.061	0.98
269_A	272_I	1.057	0.98
508_S	517_S	1.056	0.98
51_T	198_M	1.050	0.98
432_V	435_E	1.049	0.98
514_L	521_A	1.049	0.98
266_S	269_A	1.041	0.97
516_S	519_L	1.041	0.97
275_K	278_K	1.036	0.97
58_T	62_S	1.036	0.97
521_A	528_V	1.024	0.97
517_S	524_P	1.016	0.97
275_K	279_I	1.015	0.97
514_L	519_L	1.012	0.97
517_S	525_V	1.010	0.97
297_Y	301_L	1.008	0.97
68_I	72_T	1.008	0.97
30_N	33_G	1.007	0.97
51_T	220_P	1.000	0.97
383_S	413_F	0.997	0.97
278_K	290_I	0.993	0.97
273_P	278_K	0.989	0.97
357_S	422_M	0.989	0.97
283_L	287_I	0.988	0.97
62_S	193_T	0.987	0.96
277_F	280_I	0.986	0.96
182_S	186_I	0.986	0.96
298_W	303_A	0.983	0.96
279_I	283_L	0.978	0.96
47_I	51_T	0.973	0.96
132_V	216_T	0.972	0.96
299_M	302_V	0.972	0.96
249_I	252_I	0.967	0.96
486_M	489_P	0.967	0.96
508_S	521_A	0.964	0.96
282_L	286_L	0.963	0.96
30_N	34_A	0.962	0.96
295_P	300_V	0.962	0.96
164_Q	170_L	0.960	0.96
298_W	301_L	0.960	0.96
514_L	518_A	0.958	0.96
21_I	25_V	0.957	0.96
163_S	168_L	0.953	0.96
508_S	519_L	0.953	0.96
223_V	239_F	0.949	0.96
336_P	339_I	0.944	0.95
61_V	65_L	0.943	0.95
394_T	405_G	0.942	0.95
352_T	465_S	0.939	0.95
26_I	29_I	0.936	0.95
508_S	516_S	0.935	0.95
279_I	282_L	0.934	0.95
44_P	48_I	0.929	0.95
512_A	518_A	0.927	0.95
513_L	521_A	0.923	0.95
198_M	243_L	0.923	0.95
518_A	523_L	0.923	0.95
297_Y	300_V	0.921	0.95
19_P	27_V	0.921	0.95
509_V	525_V	0.920	0.95
297_Y	308_T	0.920	0.95
515_A	525_V	0.914	0.95
226_M	232_N	0.914	0.95
172_Q	444_N	0.913	0.95
301_L	306_P	0.908	0.94
345_S	469_A	0.906	0.94
390_V	408_L	0.904	0.94
524_P	527_I	0.903	0.94
265_F	270_I	0.903	0.94
135_V	203_L	0.902	0.94
274_D	282_L	0.902	0.94
302_V	305_R	0.899	0.94
200_N	383_S	0.895	0.94
340_S	343_I	0.892	0.94
218_T	221_L	0.890	0.94
15_F	19_P	0.886	0.94
300_V	304_T	0.886	0.94
292_L	300_V	0.885	0.94
276_I	280_I	0.882	0.94
418_A	465_S	0.880	0.93
282_L	285_S	0.880	0.93
273_P	283_L	0.879	0.93
147_L	189_A	0.878	0.93
140_S	197_S	0.873	0.93
516_S	523_L	0.873	0.93
55_S	198_M	0.871	0.93
291_F	299_M	0.866	0.93
157_K	160_K	0.862	0.93
54_F	58_T	0.861	0.93
31_F	34_A	0.861	0.93
155_I	182_S	0.859	0.93
289_I	294_F	0.858	0.93
426_Y	450_I	0.858	0.93
511_W	522_S	0.856	0.92
45_P	48_I	0.855	0.92
421_T	461_T	0.853	0.92
515_A	523_L	0.848	0.92
279_I	295_P	0.846	0.92
191_L	251_A	0.846	0.92
288_I	295_P	0.846	0.92
138_W	291_F	0.845	0.92
35_I	39_F	0.845	0.92
281_A	284_I	0.843	0.92
132_V	204_P	0.838	0.92
159_I	181_Y	0.835	0.92
170_L	174_Y	0.834	0.91
349_G	353_I	0.834	0.91
52_F	56_L	0.832	0.91
265_F	269_A	0.832	0.91
101_V	127_S	0.828	0.91
53_F	133_S	0.825	0.91
11_Y	15_F	0.825	0.91
347_I	351_L	0.825	0.91
274_D	281_A	0.825	0.91
274_D	284_I	0.823	0.91
403_W	407_A	0.823	0.91
148_I	182_S	0.822	0.91
280_I	303_A	0.821	0.91
483_P	486_M	0.819	0.91
296_V	299_M	0.818	0.91
104_F	126_K	0.816	0.91
509_V	520_V	0.815	0.91
160_K	164_Q	0.813	0.90
63_T	144_A	0.813	0.90
54_F	132_V	0.813	0.90
293_D	301_L	0.812	0.90
518_A	524_P	0.811	0.90
341_S	345_S	0.808	0.90
302_V	306_P	0.807	0.90
288_I	299_M	0.805	0.90
344_V	403_W	0.805	0.90
53_F	56_L	0.805	0.90
109_G	112_T	0.803	0.90
266_S	270_I	0.801	0.90
341_S	381_L	0.801	0.90
295_P	303_A	0.800	0.90
154_S	428_D	0.799	0.90
280_I	301_L	0.798	0.90
436_A	439_I	0.796	0.89
274_D	291_F	0.795	0.89
37_S	40_S	0.794	0.89
341_S	489_P	0.793	0.89
410_S	472_L	0.793	0.89
286_L	290_I	0.792	0.89
274_D	279_I	0.790	0.89
148_I	152_L	0.788	0.89
25_V	29_I	0.787	0.89
96_S	139_S	0.786	0.89
361_Y	426_Y	0.785	0.89
65_L	141_V	0.784	0.89
295_P	306_P	0.783	0.89
277_F	287_I	0.781	0.89
287_I	302_V	0.779	0.88
520_V	525_V	0.778	0.88
301_L	308_T	0.776	0.88
515_A	522_S	0.776	0.88
185_G	189_A	0.775	0.88
49_Y	52_F	0.774	0.88
517_S	528_V	0.773	0.88
278_K	284_I	0.772	0.88
101_V	206_V	0.771	0.88
522_S	528_V	0.769	0.88
360_A	422_M	0.769	0.88
148_I	189_A	0.765	0.88
284_I	292_L	0.765	0.88
357_S	446_I	0.764	0.87
13_A	21_I	0.764	0.87
57_F	61_V	0.763	0.87
512_A	517_S	0.761	0.87
406_L	410_S	0.761	0.87
288_I	303_A	0.758	0.87
288_I	306_P	0.757	0.87
217_T	222_I	0.754	0.87
173_Y	177_V	0.754	0.87
509_V	522_S	0.753	0.87
286_L	291_F	0.753	0.87
290_I	301_L	0.752	0.87
275_K	280_I	0.751	0.87
10_V	14_V	0.750	0.87
22_L	26_I	0.748	0.86
82_I	153_K	0.746	0.86
69_L	141_V	0.745	0.86
118_N	121_P	0.745	0.86
219_L	239_F	0.745	0.86
290_I	297_Y	0.745	0.86
522_S	525_V	0.742	0.86
302_V	308_T	0.741	0.86
442_M	449_L	0.741	0.86
331_L	334_S	0.737	0.86
67_Y	144_A	0.735	0.85
293_D	298_W	0.734	0.85
515_A	519_L	0.733	0.85
58_T	197_S	0.733	0.85
72_T	280_I	0.732	0.85
282_L	299_M	0.732	0.85
380_A	383_S	0.730	0.85
500_A	504_I	0.729	0.85
274_D	287_I	0.724	0.85
341_S	476_P	0.723	0.84
422_M	454_S	0.722	0.84
295_P	298_W	0.722	0.84
481_E	484_Y	0.722	0.84
175_F	179_F	0.720	0.84
474_F	477_L	0.718	0.84
201_F	205_Y	0.716	0.84
254_V	258_V	0.714	0.84
284_I	299_M	0.714	0.84
296_V	302_V	0.712	0.84
447_L	451_L	0.710	0.83
222_I	225_F	0.710	0.83
510_N	519_L	0.709	0.83
286_L	293_D	0.708	0.83
100_W	473_L	0.707	0.83
98_L	231_D	0.707	0.83
273_P	299_M	0.707	0.83
35_I	38_S	0.707	0.83
64_L	304_T	0.707	0.83
338_I	488_F	0.706	0.83
438_E	445_K	0.704	0.83
294_F	298_W	0.704	0.83
282_L	295_P	0.702	0.83
141_V	145_F	0.702	0.83
457_F	461_T	0.701	0.83
36_K	40_S	0.700	0.82
100_W	104_F	0.699	0.82
94_T	200_N	0.695	0.82
110_W	114_F	0.694	0.82
62_S	144_A	0.693	0.82
500_A	516_S	0.691	0.82
96_S	162_S	0.688	0.81
502_N	505_S	0.688	0.81
445_K	448_K	0.688	0.81
298_W	306_P	0.687	0.81
344_V	476_P	0.685	0.81
226_M	235_G	0.685	0.81
359_G	375_S	0.685	0.81
480_S	498_I	0.685	0.81
343_I	403_W	0.683	0.81
519_L	522_S	0.682	0.81
280_I	291_F	0.682	0.81
152_L	178_A	0.681	0.81
451_L	454_S	0.680	0.81
343_I	407_A	0.680	0.81
74_D	153_K	0.679	0.81
288_I	300_V	0.679	0.81
353_I	462_F	0.678	0.80
131_A	413_F	0.677	0.80
200_N	474_F	0.677	0.80
404_I	407_A	0.677	0.80
58_T	136_S	0.676	0.80
223_V	243_L	0.675	0.80
510_N	525_V	0.675	0.80
82_I	149_L	0.674	0.80
501_L	505_S	0.674	0.80
301_L	304_T	0.673	0.80
275_K	281_A	0.670	0.80
387_I	474_F	0.669	0.80
48_I	52_F	0.668	0.79
360_A	423_F	0.668	0.79
511_W	525_V	0.668	0.79
59_A	194_F	0.668	0.79
112_T	115_L	0.666	0.79
151_S	182_S	0.665	0.79
446_I	450_I	0.664	0.79
292_L	305_R	0.663	0.79
513_L	524_P	0.662	0.79
61_V	64_L	0.661	0.79
202_D	383_S	0.660	0.79
285_S	288_I	0.659	0.79
131_A	224_Y	0.658	0.78
62_S	141_V	0.657	0.78
56_L	190_F	0.657	0.78
422_M	458_L	0.655	0.78
298_W	305_R	0.653	0.78
356_S	419_F	0.653	0.78
342_I	377_Y	0.652	0.78
67_Y	152_L	0.652	0.78
306_P	325_S	0.651	0.78
291_F	302_V	0.651	0.78
75_I	78_K	0.650	0.78
50_N	53_F	0.649	0.78
443_K	448_K	0.648	0.77
189_A	193_T	0.648	0.77
508_S	524_P	0.648	0.77
406_L	475_Y	0.647	0.77
23_T	381_L	0.647	0.77
275_K	284_I	0.647	0.77
451_L	458_L	0.646	0.77
202_D	473_L	0.645	0.77
522_S	526_V	0.644	0.77
93_F	203_L	0.643	0.77
523_L	527_I	0.643	0.77
276_I	447_L	0.641	0.77
202_D	472_L	0.641	0.77
342_I	346_L	0.639	0.76
201_F	386_Y	0.639	0.76
97_A	389_P	0.638	0.76
486_M	502_N	0.634	0.76
35_I	238_L	0.634	0.76
292_L	302_V	0.633	0.76
354_L	527_I	0.633	0.76
296_V	300_V	0.631	0.76
191_L	390_V	0.630	0.75
94_T	474_F	0.629	0.75
38_S	238_L	0.628	0.75
376_I	419_F	0.628	0.75
136_S	200_N	0.628	0.75
465_S	469_A	0.627	0.75
54_F	216_T	0.625	0.75
508_S	518_A	0.625	0.75
26_I	31_F	0.622	0.74
278_K	295_P	0.622	0.74
126_K	131_A	0.621	0.74
379_Y	413_F	0.621	0.74
181_Y	184_K	0.621	0.74
510_N	524_P	0.620	0.74
111_F	114_F	0.620	0.74
169_T	175_F	0.619	0.74
286_L	301_L	0.619	0.74
243_L	382_P	0.618	0.74
87_L	174_Y	0.618	0.74
280_I	297_Y	0.617	0.74
305_R	322_F	0.617	0.74
131_A	345_S	0.615	0.74
19_P	23_T	0.615	0.74
351_L	407_A	0.614	0.74
59_A	63_T	0.614	0.74
391_Y	394_T	0.613	0.73
27_V	30_N	0.613	0.73
394_T	412_I	0.611	0.73
510_N	520_V	0.611	0.73
293_D	305_R	0.611	0.73
56_L	280_I	0.610	0.73
65_L	137_A	0.610	0.73
348_V	407_A	0.610	0.73
281_A	303_A	0.608	0.73
402_T	405_G	0.607	0.73
51_T	412_I	0.606	0.73
391_Y	400_I	0.606	0.73
426_Y	454_S	0.605	0.72
132_V	221_L	0.605	0.72
365_R	431_K	0.604	0.72
273_P	281_A	0.603	0.72
24_F	28_G	0.603	0.72
301_L	307_N	0.601	0.72
88_P	192_I	0.600	0.72
510_N	514_L	0.600	0.72
55_S	59_A	0.598	0.72
359_G	419_F	0.597	0.71
283_L	290_I	0.596	0.71
44_P	218_T	0.596	0.71
79_K	82_I	0.596	0.71
406_L	476_P	0.596	0.71
350_V	354_L	0.595	0.71
220_P	243_L	0.594	0.71
335_V	338_I	0.594	0.71
175_F	183_L	0.594	0.71
390_V	412_I	0.592	0.71
293_D	302_V	0.592	0.71
50_N	221_L	0.591	0.71
179_F	183_L	0.591	0.71
92_P	202_D	0.590	0.71
194_F	204_P	0.589	0.70
58_T	129_L	0.589	0.70
256_L	260_S	0.589	0.70
51_T	333_S	0.588	0.70
95_A	99_I	0.587	0.70
287_I	292_L	0.587	0.70
249_I	346_L	0.586	0.70
299_M	308_T	0.586	0.70
273_P	280_I	0.584	0.70
221_L	467_T	0.583	0.70
270_I	273_P	0.583	0.70
162_S	165_I	0.582	0.70
508_S	520_V	0.582	0.70
149_L	153_K	0.582	0.70
288_I	305_R	0.581	0.69
281_A	291_F	0.581	0.69
93_F	388_I	0.581	0.69
19_P	22_L	0.579	0.69
217_T	225_F	0.578	0.69
47_I	207_M	0.577	0.69
196_L	380_A	0.576	0.69
400_I	405_G	0.576	0.69
14_V	19_P	0.576	0.69
366_K	369_F	0.576	0.69
196_L	199_G	0.575	0.69
290_I	293_D	0.574	0.68
283_L	295_P	0.574	0.68
522_S	527_I	0.574	0.68
258_V	261_K	0.573	0.68
274_D	283_L	0.571	0.68
65_L	138_W	0.571	0.68
28_G	297_Y	0.570	0.68
414_T	465_S	0.569	0.68
200_N	471_H	0.569	0.68
292_L	297_Y	0.569	0.68
284_I	288_I	0.569	0.68
404_I	412_I	0.568	0.68
42_A	64_L	0.568	0.68
300_V	519_L	0.567	0.68
274_D	299_M	0.566	0.67
274_D	285_S	0.565	0.67
94_T	473_L	0.565	0.67
472_L	487_N	0.565	0.67
189_A	476_P	0.564	0.67
69_L	85_I	0.564	0.67
348_V	411_A	0.563	0.67
304_T	324_L	0.563	0.67
136_S	204_P	0.562	0.67
515_A	524_P	0.562	0.67
96_S	138_W	0.559	0.66
345_S	466_F	0.558	0.66
281_A	292_L	0.557	0.66
70_A	74_D	0.557	0.66
348_V	410_S	0.557	0.66
169_T	173_Y	0.557	0.66
85_I	141_V	0.556	0.66
438_E	454_S	0.555	0.66
271_K	276_I	0.555	0.66
74_D	149_L	0.554	0.66
142_P	383_S	0.554	0.66
26_I	392_L	0.553	0.66
11_Y	19_P	0.553	0.66
384_T	393_M	0.552	0.66
7_P	19_P	0.552	0.66
329_S	333_S	0.551	0.65
226_M	229_Q	0.550	0.65
454_S	458_L	0.549	0.65
218_T	222_I	0.548	0.65
390_V	409_P	0.546	0.65
353_I	422_M	0.546	0.65
143_L	196_L	0.546	0.65
155_I	178_A	0.546	0.65
286_L	409_P	0.545	0.65
361_Y	434_E	0.545	0.65
105_Y	108_Y	0.545	0.65
517_S	523_L	0.542	0.64
264_R	431_K	0.540	0.64
263_F	266_S	0.539	0.64
24_F	241_S	0.538	0.64
114_F	443_K	0.538	0.64
452_P	466_F	0.537	0.63
337_Y	499_F	0.537	0.63
232_N	386_Y	0.536	0.63
188_L	420_W	0.536	0.63
89_F	143_L	0.535	0.63
277_F	289_I	0.534	0.63
255_A	259_K	0.534	0.63
148_I	185_G	0.533	0.63
73_V	81_L	0.533	0.63
20_L	24_F	0.533	0.63
295_P	305_R	0.532	0.63
434_E	445_K	0.531	0.63
59_A	193_T	0.529	0.62
360_A	419_F	0.529	0.62
268_P	271_K	0.529	0.62
509_V	523_L	0.528	0.62
64_L	447_L	0.527	0.62
7_P	354_L	0.527	0.62
473_L	487_N	0.527	0.62
200_N	203_L	0.526	0.62
417_F	430_P	0.526	0.62
277_F	295_P	0.525	0.62
69_L	73_V	0.524	0.62
66_G	145_F	0.523	0.61
278_K	287_I	0.523	0.61
21_I	24_F	0.523	0.61
390_V	451_L	0.522	0.61
70_A	148_I	0.520	0.61
413_F	472_L	0.520	0.61
375_S	419_F	0.519	0.61
498_I	503_A	0.517	0.61
102_I	105_Y	0.517	0.61
42_A	46_E	0.517	0.61
196_L	474_F	0.517	0.61
410_S	413_F	0.516	0.60
58_T	137_A	0.516	0.60
413_F	468_F	0.514	0.60
393_M	398_H	0.514	0.60
93_F	96_S	0.514	0.60
420_W	471_H	0.514	0.60
287_I	399_L	0.513	0.60
136_S	140_S	0.513	0.60
256_L	294_F	0.513	0.60
425_F	454_S	0.513	0.60
190_F	356_S	0.512	0.60
100_W	143_L	0.512	0.60
285_S	289_I	0.511	0.60
241_S	245_L	0.510	0.59
329_S	332_E	0.510	0.59
325_S	351_L	0.510	0.59
221_L	503_A	0.510	0.59
196_L	379_Y	0.509	0.59
450_I	453_L	0.509	0.59
12_I	16_G	0.509	0.59
112_T	117_I	0.508	0.59
201_F	501_L	0.508	0.59
516_S	522_S	0.507	0.59
185_G	479_L	0.507	0.59
516_S	525_V	0.507	0.59
280_I	523_L	0.506	0.59
157_K	449_L	0.506	0.59
299_M	307_N	0.506	0.59
391_Y	395_S	0.506	0.59
51_T	151_S	0.504	0.59
168_L	173_Y	0.504	0.59
60_V	399_L	0.504	0.59
353_I	356_S	0.502	0.58
288_I	293_D	0.502	0.58
60_V	249_I	0.502	0.58
288_I	296_V	0.502	0.58
513_L	522_S	0.502	0.58
46_E	50_N	0.501	0.58
97_A	202_D	0.501	0.58
510_N	528_V	0.501	0.58
292_L	298_W	0.501	0.58
183_L	258_V	0.501	0.58
377_Y	467_T	0.500	0.58
140_S	196_L	0.500	0.58
93_F	199_G	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2onkC	2	0.4471	100	0.695	Contact Map
4tquM	1	0.4726	100	0.696	Contact Map
4tquN	1	0.4763	100	0.699	Contact Map
3d31C	2	0.4453	100	0.703	Contact Map
3rlfG	1	0.4726	100	0.703	Contact Map
3rlfF	1	0.4562	100	0.707	Contact Map
4ymuD	2	0.385	99.9	0.783	Contact Map
3tuiA	2	0.3759	99.9	0.792	Contact Map
4c7rA	3	0.4526	4.6	0.981	Contact Map
3mktA	1	0.646	3.5	0.982	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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