Q97V96 - SULSO - GREMLIN Contacts

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Q97V96 - 4-hydroxybutyryl-CoA dehydratase (AbfD-2)

UniProt:	Q97V96	Sequences: MVLRTGEEYVNAIRHRNKVEIYVMGKEVKDVTEHPFLKPSVLAFKATYDAAHEEDSESLARAWSSFINEEVNRFTHIHRSPEDLAAKVKLLRKISHKTGACFQRCVGWDALNAIYVTSRLMAERGKKEYYERFVEYLKYVQKNDVALAGAMTDVKGIRTLRPHEQPHAYLRVTQVTKDGIYVSGAKANITGIGAAEEIVVMPTRAMSEKDMDFAVAFSIPLDTEGIKVIIGRQVNDGRRLEEGEIDGLPYRTNHEGLVIFDNVFVPMERVFMLGDWQMSGILVEIFSSYHRQGYGGCKSGLGDVIIGAAYNLAKQIGVEKAPHIQNKLNEMVLLNENMYGSGIAASLDAVKLCEDGCWWVNPMFANVTKQLVTRFPYEITKFSTDIAGGIIGTAPSEWDLKNPKLKPYIEKYLQGMMDYSTEDRLRMVRLLENVGFSVAFLIESVHGAGSPEAQRIAINRVYDYEYAEKIAKYLSQIEKRIDFKENAEPWRKTDTEKIASSG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	502 (467)
Sequences:	818 (514)
Seq/√Len:	23.8

BACSU - YOAI
SULSO - Q97V96 Q97WR4 Q97VV3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
183_S	262_N	7.860	1.00
139_Y	143_N	5.459	1.00
10_V	41_V	5.382	1.00
406_K	410_E	4.883	1.00
26_K	34_H	4.516	1.00
182_V	217_F	4.486	1.00
12_A	196_E	4.358	1.00
349_A	358_W	4.190	1.00
30_D	33_E	4.126	1.00
180_I	270_V	3.781	1.00
14_R	30_D	3.548	1.00
400_L	425_L	3.539	1.00
172_V	273_L	3.530	1.00
267_M	270_V	3.428	1.00
197_E	269_R	3.347	1.00
6_G	49_D	3.339	1.00
176_T	264_F	3.309	1.00
63_W	70_E	3.230	1.00
176_T	181_Y	3.210	1.00
135_E	138_K	2.989	1.00
15_H	19_V	2.974	1.00
178_D	264_F	2.927	1.00
175_V	274_G	2.923	1.00
57_E	70_E	2.913	1.00
14_R	32_T	2.908	1.00
471_A	475_S	2.901	1.00
229_I	259_I	2.890	0.99
218_S	271_F	2.864	0.99
175_V	273_L	2.795	0.99
180_I	215_V	2.793	0.99
400_L	409_I	2.772	0.99
313_A	328_L	2.721	0.99
314_K	468_E	2.545	0.99
378_E	381_K	2.500	0.99
324_I	386_I	2.499	0.99
309_A	331_M	2.490	0.98
73_R	86_A	2.483	0.98
330_E	378_E	2.438	0.98
170_L	182_V	2.385	0.98
20_E	227_K	2.353	0.98
174_Q	178_D	2.352	0.98
8_E	11_N	2.345	0.98
181_Y	264_F	2.339	0.98
5_T	52_H	2.290	0.97
64_S	67_I	2.272	0.97
64_S	71_V	2.263	0.97
5_T	8_E	2.193	0.97
174_Q	262_N	2.191	0.96
259_I	408_Y	2.146	0.96
4_R	12_A	2.144	0.96
16_R	19_V	2.134	0.96
4_R	196_E	2.122	0.96
26_K	398_W	2.090	0.95
79_R	83_D	2.009	0.94
136_Y	197_E	1.967	0.94
318_V	324_I	1.963	0.94
131_E	135_E	1.944	0.93
69_E	142_K	1.922	0.93
174_Q	181_Y	1.909	0.93
420_S	423_D	1.909	0.93
350_V	361_N	1.901	0.92
7_E	11_N	1.890	0.92
155_K	390_I	1.881	0.92
170_L	260_F	1.867	0.92
212_D	274_G	1.855	0.91
303_D	339_Y	1.850	0.91
65_S	71_V	1.846	0.91
61_R	70_E	1.830	0.91
311_N	472_K	1.823	0.91
98_T	102_F	1.823	0.91
80_S	358_W	1.820	0.91
327_K	385_D	1.777	0.90
63_W	67_I	1.764	0.89
82_E	86_A	1.763	0.89
230_I	254_H	1.741	0.89
308_A	434_V	1.710	0.88
153_D	186_K	1.612	0.84
20_E	27_E	1.599	0.84
122_A	286_F	1.579	0.83
60_A	90_L	1.577	0.83
6_G	45_K	1.575	0.83
96_H	300_G	1.571	0.83
92_R	96_H	1.556	0.82
190_T	231_G	1.550	0.82
267_M	273_L	1.529	0.81
229_I	408_Y	1.519	0.80
173_T	181_Y	1.513	0.80
314_K	319_E	1.450	0.77
56_S	93_K	1.443	0.77
172_V	215_V	1.437	0.77
122_A	127_K	1.434	0.76
136_Y	218_S	1.431	0.76
302_G	379_I	1.408	0.75
402_N	405_L	1.404	0.75
231_G	253_N	1.403	0.75
323_H	327_K	1.399	0.75
88_V	346_S	1.398	0.75
270_V	273_L	1.397	0.74
135_E	139_Y	1.397	0.74
136_Y	139_Y	1.390	0.74
465_E	468_E	1.381	0.74
66_F	138_K	1.378	0.73
180_I	264_F	1.376	0.73
136_Y	269_R	1.374	0.73
128_E	131_E	1.374	0.73
415_G	419_Y	1.368	0.73
275_D	278_M	1.336	0.71
232_R	243_G	1.335	0.71
390_I	395_P	1.325	0.70
173_T	183_S	1.324	0.70
200_V	260_F	1.316	0.70
160_L	164_E	1.315	0.70
98_T	373_T	1.314	0.70
47_T	94_I	1.313	0.70
123_E	354_E	1.312	0.70
100_A	231_G	1.310	0.70
16_R	222_D	1.309	0.69
208_E	276_W	1.308	0.69
227_K	408_Y	1.308	0.69
465_E	469_K	1.291	0.68
51_A	72_N	1.288	0.68
378_E	382_F	1.282	0.68
99_G	474_L	1.278	0.68
392_G	395_P	1.265	0.67
81_P	358_W	1.259	0.66
76_H	294_Y	1.246	0.66
472_K	475_S	1.245	0.65
175_V	267_M	1.242	0.65
361_N	364_F	1.241	0.65
202_P	213_F	1.240	0.65
219_I	265_V	1.232	0.65
313_A	318_V	1.230	0.65
472_K	476_Q	1.230	0.65
119_R	134_V	1.219	0.64
132_R	268_E	1.218	0.64
381_K	445_V	1.213	0.63
219_I	223_T	1.211	0.63
471_A	476_Q	1.204	0.63
422_E	426_R	1.203	0.63
409_I	425_L	1.198	0.62
139_Y	145_V	1.196	0.62
306_I	331_M	1.196	0.62
106_V	149_G	1.194	0.62
131_E	134_V	1.191	0.62
132_R	270_V	1.186	0.62
49_D	52_H	1.176	0.61
315_Q	419_Y	1.175	0.61
316_I	388_G	1.173	0.61
66_F	71_V	1.169	0.60
305_I	431_L	1.169	0.60
388_G	391_I	1.168	0.60
25_G	399_D	1.162	0.60
384_T	445_V	1.140	0.59
81_P	347_L	1.132	0.58
255_E	301_L	1.129	0.58
265_V	269_R	1.128	0.58
220_P	265_V	1.124	0.57
312_L	431_L	1.115	0.57
259_I	412_Y	1.115	0.57
127_K	130_Y	1.111	0.57
54_E	61_R	1.105	0.56
470_I	473_Y	1.104	0.56
145_V	197_E	1.102	0.56
439_A	443_E	1.102	0.56
171_R	212_D	1.100	0.56
3_L	69_E	1.095	0.55
301_L	444_S	1.086	0.55
181_Y	215_V	1.080	0.54
39_P	42_L	1.077	0.54
167_H	411_K	1.075	0.54
43_A	99_G	1.074	0.54
199_V	335_N	1.069	0.54
108_W	149_G	1.069	0.54
198_I	221_L	1.069	0.54
200_V	217_F	1.068	0.54
100_A	253_N	1.068	0.54
327_K	382_F	1.066	0.53
157_I	160_L	1.065	0.53
312_L	386_I	1.064	0.53
183_S	200_V	1.058	0.53
337_N	371_L	1.058	0.53
217_F	265_V	1.056	0.53
167_H	183_S	1.054	0.53
71_V	141_Q	1.046	0.52
407_P	410_E	1.046	0.52
429_R	447_G	1.041	0.52
295_G	299_S	1.038	0.51
150_A	189_I	1.038	0.51
181_Y	262_N	1.036	0.51
164_E	209_K	1.036	0.51
11_N	14_R	1.033	0.51
463_D	466_Y	1.032	0.51
153_D	286_F	1.032	0.51
121_M	125_G	1.030	0.51
136_Y	147_L	1.029	0.51
253_N	439_A	1.026	0.51
257_L	413_L	1.025	0.50
388_G	450_S	1.022	0.50
377_Y	381_K	1.016	0.50
470_I	475_S	1.016	0.50
450_S	453_A	1.013	0.50
192_I	228_V	1.005	0.49
139_Y	197_E	1.004	0.49
388_G	392_G	0.998	0.49
113_A	140_V	0.993	0.48
146_A	191_G	0.985	0.48
133_F	137_L	0.984	0.48
138_K	180_I	0.980	0.47
21_I	177_K	0.978	0.47
139_Y	147_L	0.962	0.46
302_G	372_V	0.961	0.46
330_E	382_F	0.953	0.45
377_Y	445_V	0.952	0.45
14_R	31_V	0.950	0.45
45_K	403_P	0.949	0.45
200_V	223_T	0.947	0.45
40_S	194_A	0.945	0.45
186_K	372_V	0.944	0.45
62_A	76_H	0.941	0.45
226_I	263_V	0.939	0.44
10_V	409_I	0.934	0.44
192_I	221_L	0.933	0.44
470_I	474_L	0.932	0.44
68_N	314_K	0.932	0.44
211_M	276_W	0.931	0.44
231_G	255_E	0.930	0.44
178_D	268_E	0.929	0.44
178_D	181_Y	0.928	0.44
140_V	147_L	0.927	0.44
27_E	403_P	0.925	0.43
161_R	164_E	0.920	0.43
14_R	222_D	0.920	0.43
131_E	270_V	0.919	0.43
11_N	21_I	0.914	0.43
439_A	444_S	0.912	0.43
156_G	414_Q	0.911	0.42
81_P	349_A	0.911	0.42
22_Y	445_V	0.910	0.42
58_S	70_E	0.909	0.42
198_I	258_V	0.909	0.42
132_R	182_V	0.904	0.42
22_Y	424_R	0.901	0.42
63_W	68_N	0.900	0.42
78_H	87_K	0.899	0.42
163_H	210_D	0.898	0.42
7_E	58_S	0.890	0.41
14_R	33_E	0.888	0.41
9_Y	139_Y	0.885	0.41
37_L	230_I	0.883	0.41
182_V	356_G	0.882	0.40
43_A	251_R	0.879	0.40
343_I	348_D	0.878	0.40
310_Y	328_L	0.877	0.40
322_P	452_E	0.877	0.40
388_G	395_P	0.877	0.40
348_D	361_N	0.876	0.40
386_I	396_S	0.875	0.40
20_E	404_K	0.868	0.40
466_Y	472_K	0.868	0.40
340_G	364_F	0.867	0.39
64_S	142_K	0.867	0.39
53_E	56_S	0.866	0.39
272_M	275_D	0.865	0.39
139_Y	142_K	0.865	0.39
231_G	443_E	0.865	0.39
21_I	172_V	0.861	0.39
144_D	217_F	0.861	0.39
312_L	428_V	0.856	0.39
231_G	439_A	0.856	0.39
467_A	470_I	0.854	0.39
261_D	345_A	0.851	0.38
152_T	169_Y	0.849	0.38
76_H	86_A	0.848	0.38
92_R	300_G	0.846	0.38
39_P	235_N	0.845	0.38
430_L	471_A	0.841	0.38
272_M	279_S	0.840	0.38
281_I	285_I	0.838	0.38
294_Y	346_S	0.838	0.38
253_N	444_S	0.833	0.37
147_L	218_S	0.833	0.37
466_Y	475_S	0.830	0.37
253_N	443_E	0.827	0.37
21_I	53_E	0.827	0.37
124_R	277_Q	0.826	0.37
67_I	138_K	0.821	0.36
390_I	394_A	0.820	0.36
446_H	450_S	0.817	0.36
332_V	462_Y	0.816	0.36
469_K	473_Y	0.811	0.36
308_A	431_L	0.810	0.36
340_G	344_A	0.809	0.36
165_Q	213_F	0.809	0.36
7_E	319_E	0.805	0.35
255_E	439_A	0.804	0.35
258_V	271_F	0.804	0.35
67_I	142_K	0.803	0.35
123_E	134_V	0.802	0.35
327_K	451_P	0.802	0.35
190_T	253_N	0.797	0.35
162_P	165_Q	0.794	0.35
440_F	447_G	0.793	0.35
103_Q	255_E	0.792	0.35
118_S	130_Y	0.790	0.34
242_E	423_D	0.789	0.34
38_K	42_L	0.789	0.34
152_T	194_A	0.788	0.34
342_G	346_S	0.785	0.34
321_A	450_S	0.781	0.34
80_S	334_L	0.781	0.34
67_I	71_V	0.780	0.34
128_E	176_T	0.780	0.34
223_T	405_L	0.780	0.34
473_Y	476_Q	0.779	0.34
100_A	244_E	0.778	0.34
244_E	433_N	0.778	0.34
79_R	135_E	0.778	0.34
173_T	262_N	0.777	0.34
158_R	317_G	0.777	0.34
332_V	464_Y	0.776	0.34
471_A	474_L	0.773	0.33
103_Q	149_G	0.771	0.33
43_A	46_A	0.770	0.33
72_N	144_D	0.770	0.33
264_F	267_M	0.770	0.33
10_V	32_T	0.769	0.33
277_Q	465_E	0.769	0.33
403_P	407_P	0.766	0.33
254_H	434_V	0.765	0.33
99_G	476_Q	0.765	0.33
71_V	142_K	0.764	0.33
121_M	272_M	0.764	0.33
160_L	167_H	0.763	0.33
326_N	374_R	0.762	0.33
172_V	465_E	0.761	0.33
223_T	263_V	0.760	0.33
34_H	45_K	0.760	0.33
29_K	55_D	0.759	0.32
9_Y	143_N	0.758	0.32
142_K	259_I	0.758	0.32
294_Y	301_L	0.755	0.32
386_I	431_L	0.751	0.32
75_T	412_Y	0.749	0.32
54_E	277_Q	0.749	0.32
397_E	401_K	0.748	0.32
26_K	29_K	0.748	0.32
259_I	427_M	0.746	0.32
73_R	76_H	0.746	0.32
250_Y	426_R	0.744	0.32
13_I	19_V	0.744	0.32
308_A	317_G	0.741	0.31
255_E	443_E	0.740	0.31
95_S	301_L	0.739	0.31
64_S	141_Q	0.739	0.31
185_A	412_Y	0.738	0.31
303_D	467_A	0.738	0.31
123_E	224_E	0.737	0.31
125_G	279_S	0.737	0.31
20_E	138_K	0.736	0.31
59_L	89_K	0.731	0.31
7_E	226_I	0.731	0.31
27_E	48_Y	0.730	0.31
315_Q	427_M	0.730	0.31
187_A	429_R	0.729	0.31
255_E	444_S	0.729	0.31
180_I	274_G	0.727	0.30
429_R	440_F	0.723	0.30
10_V	42_L	0.722	0.30
183_S	213_F	0.721	0.30
227_K	259_I	0.721	0.30
117_T	312_L	0.720	0.30
96_H	470_I	0.720	0.30
55_D	58_S	0.719	0.30
8_E	274_G	0.718	0.30
372_V	440_F	0.714	0.30
28_V	38_K	0.714	0.30
187_A	409_I	0.713	0.30
82_E	85_A	0.711	0.30
129_Y	132_R	0.710	0.29
384_T	441_L	0.710	0.29
180_I	273_L	0.709	0.29
373_T	454_Q	0.708	0.29
144_D	197_E	0.708	0.29
187_A	190_T	0.707	0.29
231_G	444_S	0.707	0.29
253_N	301_L	0.706	0.29
337_N	341_S	0.706	0.29
85_A	347_L	0.699	0.29
33_E	181_Y	0.697	0.29
77_I	114_I	0.697	0.29
21_I	279_S	0.697	0.29
314_K	416_M	0.697	0.29
426_R	475_S	0.696	0.29
402_N	406_K	0.696	0.29
12_A	15_H	0.696	0.29
224_E	357_C	0.695	0.29
415_G	424_R	0.695	0.29
117_T	353_C	0.695	0.29
364_F	381_K	0.695	0.29
369_K	373_T	0.694	0.29
80_S	320_K	0.693	0.28
410_E	420_S	0.692	0.28
210_D	226_I	0.692	0.28
33_E	410_E	0.691	0.28
355_D	361_N	0.690	0.28
178_D	412_Y	0.689	0.28
191_G	440_F	0.689	0.28
136_Y	193_G	0.689	0.28
103_Q	443_E	0.688	0.28
66_F	268_E	0.687	0.28
23_V	43_A	0.686	0.28
37_L	299_S	0.679	0.28
385_D	388_G	0.677	0.28
28_V	33_E	0.677	0.28
394_A	425_L	0.677	0.28
15_H	30_D	0.677	0.28
312_L	387_A	0.676	0.28
197_E	265_V	0.676	0.28
226_I	258_V	0.675	0.27
227_K	402_N	0.675	0.27
466_Y	474_L	0.672	0.27
187_A	257_L	0.671	0.27
142_K	383_S	0.671	0.27
28_V	469_K	0.671	0.27
15_H	222_D	0.670	0.27
399_D	430_L	0.670	0.27
27_E	178_D	0.668	0.27
100_A	255_E	0.668	0.27
180_I	262_N	0.668	0.27
226_I	260_F	0.667	0.27
198_I	288_S	0.666	0.27
397_E	426_R	0.665	0.27
310_Y	464_Y	0.665	0.27
83_D	214_A	0.664	0.27
329_N	333_L	0.664	0.27
228_V	256_G	0.661	0.27
20_E	31_V	0.661	0.27
327_K	388_G	0.661	0.27
83_D	420_S	0.660	0.27
443_E	447_G	0.659	0.27
219_I	263_V	0.658	0.27
160_L	165_Q	0.658	0.27
223_T	250_Y	0.657	0.26
131_E	222_D	0.656	0.26
147_L	199_V	0.656	0.26
312_L	427_M	0.656	0.26
139_Y	269_R	0.655	0.26
347_L	407_P	0.654	0.26
236_D	246_D	0.654	0.26
24_M	399_D	0.653	0.26
200_V	428_V	0.652	0.26
301_L	439_A	0.651	0.26
186_K	474_L	0.650	0.26
331_M	379_I	0.650	0.26
467_A	474_L	0.650	0.26
21_I	31_V	0.649	0.26
148_A	189_I	0.649	0.26
37_L	204_R	0.648	0.26
152_T	454_Q	0.647	0.26
432_E	439_A	0.647	0.26
288_S	360_V	0.646	0.26
46_A	97_K	0.646	0.26
318_V	379_I	0.645	0.26
406_K	421_T	0.645	0.26
259_I	421_T	0.644	0.26
174_Q	264_F	0.643	0.26
156_G	162_P	0.642	0.26
159_T	317_G	0.641	0.26
316_I	428_V	0.641	0.26
154_V	185_A	0.641	0.26
103_Q	432_E	0.639	0.25
325_Q	456_I	0.639	0.25
309_A	340_G	0.637	0.25
45_K	230_I	0.637	0.25
408_Y	412_Y	0.637	0.25
100_A	444_S	0.636	0.25
5_T	12_A	0.636	0.25
220_P	271_F	0.636	0.25
305_I	469_K	0.635	0.25
43_A	409_I	0.634	0.25
335_N	437_S	0.633	0.25
23_V	307_G	0.632	0.25
160_L	209_K	0.632	0.25
213_F	388_G	0.631	0.25
102_F	180_I	0.630	0.25
92_R	303_D	0.630	0.25
106_V	432_E	0.630	0.25
155_K	158_R	0.630	0.25
103_Q	253_N	0.630	0.25
22_Y	227_K	0.629	0.25
302_G	335_N	0.629	0.25
64_S	69_E	0.628	0.25
37_L	40_S	0.628	0.25
176_T	267_M	0.627	0.25
9_Y	265_V	0.624	0.25
22_Y	115_Y	0.624	0.25
40_S	274_G	0.623	0.25
6_G	52_H	0.623	0.25
224_E	262_N	0.622	0.25
58_S	319_E	0.621	0.25
63_W	66_F	0.621	0.25
183_S	227_K	0.619	0.24
20_E	405_L	0.618	0.24
57_E	86_A	0.618	0.24
94_I	382_F	0.618	0.24
227_K	404_K	0.617	0.24
103_Q	188_N	0.615	0.24
376_P	384_T	0.613	0.24
65_S	70_E	0.613	0.24
10_V	45_K	0.611	0.24
106_V	295_G	0.611	0.24
337_N	340_G	0.610	0.24
231_G	433_N	0.610	0.24
8_E	82_E	0.610	0.24
182_V	265_V	0.609	0.24
343_I	400_L	0.609	0.24
301_L	443_E	0.608	0.24
212_D	377_Y	0.608	0.24
311_N	329_N	0.608	0.24
72_N	90_L	0.606	0.24
213_F	262_N	0.606	0.24
85_A	346_S	0.603	0.24
118_S	127_K	0.603	0.24
255_E	433_N	0.601	0.24
30_D	465_E	0.601	0.24
163_H	176_T	0.600	0.23
19_V	221_L	0.600	0.23
241_E	406_K	0.599	0.23
23_V	28_V	0.598	0.23
75_T	137_L	0.598	0.23
138_K	142_K	0.597	0.23
72_N	271_F	0.597	0.23
198_I	228_V	0.595	0.23
26_K	262_N	0.595	0.23
4_R	140_V	0.594	0.23
150_A	200_V	0.593	0.23
436_F	440_F	0.592	0.23
27_E	172_V	0.592	0.23
401_K	422_E	0.592	0.23
296_G	342_G	0.592	0.23
190_T	251_R	0.590	0.23
140_V	218_S	0.589	0.23
21_I	409_I	0.589	0.23
410_E	473_Y	0.587	0.23
311_N	427_M	0.587	0.23
58_S	86_A	0.586	0.23
9_Y	52_H	0.586	0.23
104_R	190_T	0.584	0.23
432_E	444_S	0.584	0.23
175_V	212_D	0.583	0.23
170_L	215_V	0.583	0.23
95_S	98_T	0.583	0.23
371_L	375_F	0.581	0.23
122_A	126_K	0.580	0.22
148_A	193_G	0.579	0.22
50_A	93_K	0.578	0.22
154_V	253_N	0.577	0.22
87_K	144_D	0.577	0.22
31_V	41_V	0.575	0.22
231_G	244_E	0.575	0.22
155_K	159_T	0.574	0.22
101_C	434_V	0.573	0.22
48_Y	146_A	0.572	0.22
3_L	8_E	0.572	0.22
176_T	183_S	0.571	0.22
391_I	395_P	0.571	0.22
154_V	439_A	0.571	0.22
343_I	347_L	0.570	0.22
169_Y	204_R	0.570	0.22
119_R	123_E	0.569	0.22
145_V	269_R	0.569	0.22
466_Y	476_Q	0.569	0.22
270_V	467_A	0.568	0.22
128_E	132_R	0.566	0.22
63_W	142_K	0.566	0.22
260_F	271_F	0.565	0.22
311_N	468_E	0.565	0.22
134_V	466_Y	0.565	0.22
177_K	267_M	0.564	0.22
226_I	403_P	0.564	0.22
12_A	191_G	0.564	0.22
75_T	78_H	0.564	0.22
332_V	391_I	0.563	0.22
162_P	167_H	0.563	0.22
328_L	361_N	0.563	0.22
58_S	405_L	0.561	0.22
242_E	398_W	0.560	0.21
219_I	269_R	0.559	0.21
302_G	447_G	0.558	0.21
26_K	82_E	0.558	0.21
8_E	182_V	0.557	0.21
14_R	38_K	0.557	0.21
453_A	457_A	0.557	0.21
286_F	290_H	0.557	0.21
367_V	456_I	0.557	0.21
186_K	447_G	0.557	0.21
22_Y	27_E	0.557	0.21
339_Y	342_G	0.556	0.21
252_T	444_S	0.556	0.21
44_F	425_L	0.555	0.21
322_P	450_S	0.555	0.21
171_R	420_S	0.554	0.21
154_V	299_S	0.554	0.21
114_I	199_V	0.553	0.21
96_H	303_D	0.553	0.21
176_T	407_P	0.552	0.21
59_L	93_K	0.552	0.21
189_I	258_V	0.551	0.21
307_G	471_A	0.551	0.21
309_A	313_A	0.550	0.21
222_D	314_K	0.548	0.21
157_I	164_E	0.548	0.21
155_K	202_P	0.546	0.21
87_K	294_Y	0.545	0.21
350_V	362_P	0.545	0.21
51_A	197_E	0.544	0.21
297_C	368_T	0.544	0.21
218_S	269_R	0.543	0.21
177_K	268_E	0.543	0.21
37_L	80_S	0.542	0.21
21_I	85_A	0.541	0.21
430_L	435_G	0.540	0.21
221_L	228_V	0.540	0.21
54_E	79_R	0.539	0.20
133_F	456_I	0.539	0.20
219_I	407_P	0.539	0.20
7_E	402_N	0.538	0.20
151_M	454_Q	0.538	0.20
465_E	471_A	0.537	0.20
323_H	450_S	0.537	0.20
436_F	439_A	0.537	0.20
329_N	337_N	0.535	0.20
107_G	439_A	0.533	0.20
58_S	135_E	0.533	0.20
197_E	218_S	0.531	0.20
143_N	178_D	0.531	0.20
128_E	267_M	0.531	0.20
231_G	301_L	0.531	0.20
223_T	260_F	0.531	0.20
197_E	336_E	0.530	0.20
172_V	406_K	0.530	0.20
146_A	338_M	0.529	0.20
161_R	169_Y	0.528	0.20
88_V	340_G	0.526	0.20
336_E	339_Y	0.525	0.20
179_G	267_M	0.525	0.20
8_E	261_D	0.524	0.20
4_R	148_A	0.523	0.20
279_S	448_A	0.522	0.20
187_A	389_G	0.522	0.20
265_V	315_Q	0.522	0.20
60_A	64_S	0.521	0.20
167_H	186_K	0.521	0.20
194_A	300_G	0.521	0.20
224_E	473_Y	0.521	0.20
122_A	125_G	0.521	0.20
14_R	261_D	0.520	0.20
243_G	246_D	0.520	0.20
53_E	134_V	0.519	0.20
296_G	447_G	0.519	0.20
265_V	323_H	0.519	0.20
88_V	92_R	0.519	0.20
151_M	287_S	0.518	0.20
12_A	16_R	0.518	0.20
80_S	260_F	0.518	0.20
311_N	430_L	0.517	0.20
185_A	259_I	0.517	0.20
181_Y	469_K	0.517	0.20
253_N	433_N	0.516	0.19
347_L	473_Y	0.516	0.19
122_A	316_I	0.513	0.19
5_T	32_T	0.512	0.19
175_V	268_E	0.511	0.19
155_K	316_I	0.511	0.19
189_I	192_I	0.510	0.19
337_N	367_V	0.509	0.19
309_A	383_S	0.509	0.19
31_V	402_N	0.508	0.19
11_N	177_K	0.507	0.19
8_E	20_E	0.507	0.19
79_R	174_Q	0.507	0.19
43_A	97_K	0.507	0.19
346_S	349_A	0.506	0.19
378_E	411_K	0.506	0.19
229_I	261_D	0.506	0.19
205_A	386_I	0.504	0.19
58_S	463_D	0.504	0.19
317_G	345_A	0.503	0.19
190_T	245_I	0.503	0.19
325_Q	329_N	0.503	0.19
138_K	305_I	0.503	0.19
59_L	328_L	0.503	0.19
24_M	328_L	0.502	0.19
6_G	401_K	0.502	0.19
28_V	319_E	0.502	0.19
54_E	70_E	0.502	0.19
50_A	97_K	0.501	0.19
126_K	409_I	0.501	0.19
395_P	424_R	0.501	0.19
279_S	292_Q	0.500	0.19

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g5eA	4	0.9104	100	0.507	Contact Map
3hwcA	4	0.9303	100	0.509	Contact Map
1u8vA	3	0.9363	100	0.519	Contact Map
4oo2A	4	0.9801	100	0.536	Contact Map
2yykA	3	0.9243	100	0.544	Contact Map
1ukwA	4	0.6992	99.7	0.899	Contact Map
2pg0A	4	0.7171	99.7	0.899	Contact Map
1ivhA	4	0.7171	99.7	0.901	Contact Map
4l1fA	4	0.6972	99.7	0.901	Contact Map
2wbiA	4	0.745	99.7	0.902	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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