GREMLIN Database
Q97V79 - Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (PorB-2)
UniProt: Q97V79 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 299 (268)
Sequences: 2439 (1210)
Seq/√Len: 73.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
121_N197_E5.6051.00
123_L200_R4.5221.00
164_P235_F4.1461.00
178_A186_Y3.9041.00
193_A202_V3.5391.00
126_T201_Y2.7971.00
218_K221_E2.7901.00
162_N165_L2.7001.00
178_A189_K2.6501.00
195_Q240_G2.5171.00
116_A167_M2.4931.00
43_V82_L2.4911.00
191_K195_Q2.4481.00
31_M98_W2.3931.00
34_L190_L2.3461.00
143_T147_A2.2481.00
222_V266_I2.2441.00
97_V122_I2.2111.00
280_I283_Q2.1971.00
16_L54_I2.1761.00
115_A122_I2.1271.00
213_L268_G2.1081.00
79_A97_V2.0991.00
261_R282_E2.0431.00
185_D189_K2.0261.00
128_D203_H1.9631.00
27_E127_V1.9281.00
173_P196_V1.8521.00
99_A124_Y1.8461.00
124_Y199_F1.8381.00
195_Q238_Y1.8221.00
116_A199_F1.7921.00
130_E160_K1.7871.00
279_K283_Q1.7861.00
34_L98_W1.7791.00
229_T258_R1.7771.00
177_T203_H1.7681.00
45_V82_L1.7581.00
125_L190_L1.7391.00
42_V94_T1.7251.00
123_L194_R1.7081.00
34_L125_L1.7061.00
75_G97_V1.6791.00
32_R36_M1.6721.00
96_V194_R1.6621.00
104_S124_Y1.6431.00
99_A104_S1.6060.99
68_V78_T1.5830.99
79_A95_I1.5380.99
207_P219_T1.5280.99
167_M201_Y1.5040.99
125_L204_V1.4960.99
179_S227_V1.4730.99
261_R265_S1.4700.99
192_K195_Q1.4650.99
112_L167_M1.4500.99
210_Y213_L1.4480.99
45_V97_V1.4440.99
31_M54_I1.4110.99
179_S223_A1.4080.99
144_P147_A1.4050.99
70_V78_T1.4040.99
41_D92_N1.3980.99
265_S274_T1.3970.98
45_V79_A1.3910.98
238_Y241_K1.3850.98
268_G272_K1.3760.98
105_A126_T1.3630.98
190_L202_V1.3600.98
43_V95_I1.3510.98
129_N133_M1.3350.98
36_M187_I1.3250.98
126_T163_L1.3230.98
30_A206_T1.3220.98
277_Q280_I1.3200.98
98_W127_V1.3170.98
225_L228_Q1.2980.98
250_H253_D1.2960.98
179_S205_L1.2950.98
31_M127_V1.2920.97
48_A69_N1.2870.97
30_A204_V1.2790.97
247_E250_H1.2760.97
104_S126_T1.2760.97
176_A189_K1.2750.97
241_K246_S1.2740.97
164_P201_Y1.2700.97
240_G243_N1.2660.97
227_V234_L1.2470.97
149_T152_T1.2450.97
196_V200_R1.2440.97
112_L124_Y1.2240.97
225_L266_I1.2180.96
178_A190_L1.2150.96
76_P124_Y1.2120.96
212_W215_D1.2080.96
128_D160_K1.2070.96
248_S252_L1.2040.96
259_P262_D1.2020.96
186_Y190_L1.2010.96
38_L194_R1.1890.96
39_G64_N1.1720.96
174_Y192_K1.1700.95
178_A185_D1.1670.95
222_V267_Q1.1510.95
157_K280_I1.1510.95
90_G93_V1.1440.95
80_A120_D1.1360.95
224_K228_Q1.1350.95
210_Y215_D1.1320.95
160_K177_T1.1260.94
236_E239_N1.1250.94
180_V220_V1.1120.94
278_I281_L1.1080.94
249_L252_L1.0940.94
230_C257_R1.0890.93
178_A204_V1.0730.93
239_N243_N1.0660.93
145_F159_N1.0640.93
46_V67_T1.0600.92
48_A53_V1.0590.92
180_V186_Y1.0580.92
164_P175_V1.0540.92
188_E192_K1.0530.92
48_A74_A1.0530.92
54_I127_V1.0480.92
119_N199_F1.0410.92
172_V175_V1.0410.92
167_M175_V1.0360.92
80_A118_R1.0360.92
248_S253_D1.0360.92
52_S69_N1.0330.91
83_A120_D1.0240.91
192_K254_R1.0240.91
31_M35_G1.0160.91
164_P177_T1.0150.91
185_D249_L1.0070.90
163_L201_Y1.0050.90
48_A52_S1.0030.90
158_E172_V0.9970.90
21_A28_N0.9940.90
256_T259_P0.9940.90
241_K244_I0.9900.90
44_L63_Y0.9890.90
34_L96_V0.9860.89
84_R120_D0.9860.89
105_A142_S0.9740.89
143_T149_T0.9710.89
94_T194_R0.9670.88
226_A263_F0.9630.88
237_Y245_S0.9630.88
258_R262_D0.9580.88
273_L281_L0.9480.87
125_L202_V0.9460.87
187_I191_K0.9440.87
59_P72_F0.9430.87
82_L95_I0.9410.87
231_Y260_I0.9410.87
240_G250_H0.9370.87
139_R152_T0.9360.87
261_R275_D0.9320.87
237_Y240_G0.9310.87
57_N60_Y0.9130.85
52_S56_G0.9120.85
228_Q257_R0.9090.85
127_V206_T0.9090.85
240_G244_I0.9070.85
260_I270_F0.9060.85
228_Q258_R0.9050.85
272_K276_E0.9010.85
238_Y250_H0.9010.85
29_M32_R0.8990.85
52_S74_A0.8950.84
38_L42_V0.8930.84
246_S250_H0.8920.84
96_V123_L0.8910.84
249_L253_D0.8840.84
41_D94_T0.8830.83
260_I264_L0.8680.82
31_M63_Y0.8650.82
71_A201_Y0.8560.82
105_A163_L0.8560.82
34_L42_V0.8520.81
110_A113_S0.8510.81
222_V225_L0.8500.81
274_T277_Q0.8500.81
261_R274_T0.8470.81
79_A122_I0.8420.80
30_A127_V0.8420.80
75_G103_G0.8290.79
29_M33_M0.8250.79
83_A95_I0.8230.79
53_V56_G0.8140.78
188_E191_K0.8130.78
38_L96_V0.8090.78
46_V55_Q0.8090.78
123_L190_L0.8060.77
211_G215_D0.8020.77
231_Y263_F0.8010.77
75_G132_Y0.8010.77
76_P115_A0.7980.77
105_A203_H0.7960.77
113_S170_H0.7940.76
261_R264_L0.7940.76
278_I282_E0.7930.76
68_V82_L0.7910.76
52_S55_Q0.7900.76
119_N172_V0.7890.76
165_L168_I0.7870.76
51_S127_V0.7820.75
239_N242_L0.7820.75
274_T281_L0.7810.75
192_K238_Y0.7780.75
232_W236_E0.7780.75
230_C236_E0.7770.75
274_T282_E0.7730.74
217_S221_E0.7720.74
179_S182_Y0.7640.74
48_A67_T0.7630.74
94_T121_N0.7580.73
72_F107_I0.7540.73
75_G99_A0.7540.73
186_Y204_V0.7450.72
241_K250_H0.7440.72
254_R282_E0.7420.71
264_L270_F0.7410.71
21_A54_I0.7360.71
38_L94_T0.7350.71
166_L169_A0.7350.71
275_D283_Q0.7340.71
71_A74_A0.7320.70
182_Y226_A0.7310.70
33_M186_Y0.7270.70
192_K236_E0.7270.70
98_W125_L0.7270.70
35_G63_Y0.7250.70
197_E240_G0.7250.70
113_S161_K0.7230.69
26_P29_M0.7150.69
19_T28_N0.7140.69
48_A72_F0.7140.69
53_V69_N0.7140.69
260_I263_F0.7120.68
220_V223_A0.7100.68
232_W239_N0.7090.68
116_A201_Y0.7080.68
50_C107_I0.7080.68
262_D265_S0.6970.67
271_K275_D0.6970.67
238_Y243_N0.6940.66
137_G148_I0.6930.66
109_F113_S0.6910.66
229_T259_P0.6910.66
34_L127_V0.6830.65
22_C25_C0.6830.65
112_L168_I0.6810.65
177_T260_I0.6790.65
48_A63_Y0.6750.64
260_I281_L0.6720.64
131_A147_A0.6710.64
145_F280_I0.6700.64
50_C81_G0.6700.64
181_G224_K0.6690.63
245_S248_S0.6680.63
205_L231_Y0.6670.63
43_V93_V0.6670.63
163_L175_V0.6660.63
181_G207_P0.6660.63
255_R268_G0.6640.63
236_E240_G0.6630.63
241_K247_E0.6630.63
56_G74_A0.6620.63
168_I224_K0.6610.63
215_D218_K0.6590.62
27_E206_T0.6590.62
15_I55_Q0.6540.62
49_G74_A0.6530.62
197_E262_D0.6530.62
81_G85_A0.6530.62
154_E157_K0.6520.62
159_N262_D0.6510.61
274_T283_Q0.6460.61
260_I265_S0.6460.61
264_L274_T0.6440.61
168_I235_F0.6430.60
92_N121_N0.6430.60
106_D141_G0.6430.60
39_G42_V0.6400.60
117_E139_R0.6380.60
33_M187_I0.6320.59
58_A61_N0.6310.59
53_V79_A0.6300.59
168_I237_Y0.6300.59
96_V125_L0.6260.58
272_K277_Q0.6250.58
274_T280_I0.6240.58
177_T233_P0.6240.58
76_P111_S0.6230.58
33_M36_M0.6170.57
254_R257_R0.6170.57
33_M183_P0.6170.57
59_P69_N0.6170.57
219_T223_A0.6150.57
135_S208_D0.6150.57
221_E225_L0.6140.57
131_A137_G0.6110.57
75_G79_A0.6080.56
51_S206_T0.6050.56
237_Y242_L0.6040.56
42_V90_G0.6020.55
277_Q283_Q0.6020.55
53_V106_D0.6020.55
139_R260_I0.6010.55
70_V74_A0.6010.55
189_K202_V0.6010.55
264_L268_G0.5990.55
107_I110_A0.5990.55
191_K197_E0.5970.55
51_S107_I0.5970.55
266_I270_F0.5960.55
233_P236_E0.5950.55
22_C208_D0.5920.54
113_S166_L0.5900.54
268_G275_D0.5900.54
45_V78_T0.5900.54
123_L202_V0.5890.54
13_N64_N0.5890.54
279_K282_E0.5840.53
93_V283_Q0.5840.53
136_G174_Y0.5810.53
160_K231_Y0.5810.53
274_T278_I0.5800.53
189_K236_E0.5790.53
109_F114_G0.5780.52
116_A124_Y0.5780.52
46_V52_S0.5770.52
261_R271_K0.5700.51
164_P168_I0.5670.51
166_L170_H0.5660.51
59_P62_A0.5650.51
230_C234_L0.5640.51
228_Q259_P0.5630.51
27_E162_N0.5610.50
144_P166_L0.5590.50
237_Y241_K0.5590.50
168_I175_V0.5560.50
209_P214_F0.5550.50
58_A83_A0.5550.50
99_A103_G0.5540.49
27_E71_A0.5520.49
143_T155_G0.5500.49
231_Y234_L0.5480.49
180_V207_P0.5470.49
82_L85_A0.5450.48
37_G180_V0.5430.48
227_V263_F0.5430.48
276_E279_K0.5380.47
239_N245_S0.5370.47
49_G71_A0.5350.47
275_D279_K0.5330.47
102_G208_D0.5330.47
214_F266_I0.5320.47
184_H188_E0.5290.46
53_V61_N0.5270.46
60_Y95_I0.5270.46
20_S53_V0.5270.46
95_I283_Q0.5260.46
50_C208_D0.5260.46
148_I273_L0.5250.46
46_V51_S0.5240.46
176_A198_G0.5230.46
139_R142_S0.5200.45
38_L123_L0.5190.45
29_M220_V0.5190.45
275_D280_I0.5190.45
238_Y245_S0.5170.45
19_T32_R0.5170.45
216_P220_V0.5170.45
48_A56_G0.5150.45
268_G271_K0.5140.45
49_G155_G0.5140.45
252_L255_R0.5120.44
47_V103_G0.5120.44
20_S52_S0.5110.44
241_K245_S0.5100.44
148_I272_K0.5090.44
263_F266_I0.5080.44
50_C170_H0.5080.44
31_M184_H0.5060.44
110_A161_K0.5050.43
242_L245_S0.5040.43
22_C50_C0.5030.43
271_K277_Q0.5030.43
235_F238_Y0.5030.43
102_G140_S0.5030.43
109_F169_A0.5010.43
260_I271_K0.5010.43
258_R271_K0.5010.43
99_A126_T0.5010.43
137_G213_L0.5010.43
114_G117_E0.5010.43
112_L116_A0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2c42A 2 1 100 0.327 Contact Map
5c4iC 2 0.9732 100 0.478 Contact Map
4kgdA 4 0.8094 99.9 0.739 Contact Map
1v5eA 4 0.8127 99.9 0.76 Contact Map
2panA 3 0.8027 99.9 0.769 Contact Map
1ybhA 4 0.7391 99.9 0.78 Contact Map
4rjjA 5 0.6957 99.9 0.783 Contact Map
1umdA 2 0.8227 99.9 0.786 Contact Map
1w85A 2 0.8562 99.9 0.786 Contact Map
2pgnA 4 0.7592 99.9 0.787 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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