GREMLIN Database
Q97V76 - Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (PorG-2)
UniProt: Q97V76 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 184 (172)
Sequences: 4461 (2933)
Seq/√Len: 223.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
151_E171_R4.2301.00
119_D123_V3.5821.00
88_L92_S3.2931.00
164_Q168_K3.1401.00
28_E149_S2.8351.00
116_I119_D2.7471.00
93_T111_V2.7321.00
154_I170_A2.5351.00
151_E167_I2.4841.00
123_V172_L2.4751.00
171_R175_G2.4651.00
152_K155_E2.4311.00
155_E167_I2.4191.00
28_E146_K2.3581.00
68_D89_K2.3581.00
172_L175_G2.1821.00
146_K149_S2.1661.00
90_D109_F1.9981.00
27_Y152_K1.9821.00
147_L174_Y1.9601.00
5_R87_G1.8741.00
69_Y138_L1.8311.00
124_K172_L1.7941.00
30_L55_D1.7891.00
140_R174_Y1.7851.00
129_M165_L1.7251.00
31_Y57_P1.7181.00
168_K172_L1.7061.00
25_A53_I1.6551.00
147_L171_R1.6361.00
164_Q167_I1.6271.00
72_V78_I1.6061.00
136_G173_A1.6051.00
139_I150_L1.5951.00
27_Y156_E1.5811.00
133_I169_G1.5771.00
120_L176_Q1.5761.00
22_A34_S1.5341.00
139_I174_Y1.5201.00
147_L151_E1.4941.00
120_L133_I1.4791.00
89_K92_S1.4771.00
120_L172_L1.4701.00
71_V138_L1.4691.00
151_E155_E1.4681.00
158_F162_V1.4581.00
3_E52_R1.4241.00
147_L170_A1.3981.00
148_S151_E1.3401.00
167_I171_R1.3251.00
96_L114_T1.3181.00
16_T158_F1.3001.00
120_L123_V1.2881.00
98_S116_I1.2871.00
97_N118_T1.2831.00
99_P116_I1.2731.00
117_A134_I1.2581.00
90_D108_T1.2551.00
124_K133_I1.2401.00
172_L176_Q1.2211.00
98_S114_T1.2131.00
116_I176_Q1.2111.00
69_Y95_L1.1971.00
137_A177_V1.1901.00
165_L168_K1.1811.00
70_L94_I1.1801.00
152_K156_E1.1751.00
168_K171_R1.1741.00
121_G133_I1.1581.00
99_P119_D1.1561.00
9_R74_D1.1551.00
95_L141_V1.1401.00
96_L112_N1.1401.00
113_A141_V1.1301.00
148_S152_K1.1281.00
139_I170_A1.1251.00
155_E163_A1.1241.00
30_L53_I1.1181.00
75_N100_S1.0981.00
94_I112_N1.0761.00
5_R50_Y1.0571.00
115_K137_A1.0531.00
73_I130_V1.0431.00
23_E156_E1.0361.00
24_A153_A1.0311.00
140_R177_V1.0131.00
64_V67_P1.0131.00
6_F21_L1.0091.00
124_K168_K1.0091.00
91_T110_Y1.0031.00
6_F14_V0.9911.00
88_L110_Y0.9861.00
124_K165_L0.9781.00
20_L132_V0.9771.00
163_A167_I0.9631.00
150_L154_I0.9311.00
113_A137_A0.9261.00
37_I48_E0.9110.99
24_A150_L0.9110.99
67_P87_G0.9060.99
88_L94_I0.8880.99
8_G14_V0.8820.99
160_G163_A0.8720.99
67_P70_L0.8700.99
117_A121_G0.8560.99
91_T109_F0.8540.99
74_D77_L0.8510.99
54_S58_I0.8490.99
169_G173_A0.8480.99
118_T130_V0.8460.99
94_I110_Y0.8420.99
103_D106_W0.8330.99
6_F51_C0.8330.99
84_L87_G0.8290.99
24_A149_S0.8270.99
11_G43_R0.8210.99
138_L142_M0.8070.99
4_I21_L0.8060.99
155_E164_Q0.8000.99
18_S49_A0.7990.99
117_A130_V0.7960.99
119_D122_L0.7910.98
3_E89_K0.7910.98
102_P178_G0.7890.98
26_G32_T0.7880.98
23_E157_E0.7870.98
72_V94_I0.7830.98
133_I173_A0.7800.98
86_R90_D0.7740.98
136_G174_Y0.7740.98
104_L114_T0.7580.98
158_F163_A0.7530.98
46_E74_D0.7520.98
17_A73_I0.7500.98
5_R67_P0.7490.98
6_F71_V0.7440.98
14_V73_I0.7430.98
93_T113_A0.7340.98
120_L124_K0.7240.97
12_Q43_R0.7240.97
27_Y149_S0.7230.97
137_A141_V0.7200.97
129_M169_G0.7140.97
64_V86_R0.7090.97
20_L153_A0.7010.97
95_L117_A0.7010.97
115_K120_L0.6990.97
46_E77_L0.6940.97
10_G39_G0.6910.96
36_P41_E0.6910.96
158_F161_K0.6870.96
170_A174_Y0.6830.96
9_R77_L0.6830.96
162_V165_L0.6810.96
15_V40_A0.6770.96
130_V134_I0.6730.96
72_V96_L0.6720.96
70_L84_L0.6700.96
23_E26_G0.6700.96
124_K129_M0.6660.96
126_G165_L0.6630.96
75_N98_S0.6620.95
46_E84_L0.6610.95
57_P60_V0.6550.95
149_S152_K0.6540.95
70_L88_L0.6530.95
149_S153_A0.6510.95
153_A157_E0.6510.95
121_G130_V0.6510.95
10_G47_I0.6500.95
139_I144_M0.6490.95
69_Y93_T0.6480.95
150_L170_A0.6430.95
4_I69_Y0.6430.95
66_E89_K0.6430.95
159_D163_A0.6350.94
15_V36_P0.6320.94
48_E84_L0.6310.94
66_E90_D0.6310.94
107_R110_Y0.6270.94
75_N79_Q0.6230.94
133_I172_L0.6220.94
19_Q34_S0.6220.94
62_S67_P0.6210.94
15_V47_I0.6200.94
50_Y63_P0.6200.94
41_E44_G0.6180.94
73_I134_I0.6120.93
25_A51_C0.6100.93
139_I147_L0.6080.93
37_I40_A0.6050.93
40_A47_I0.6030.93
140_R178_G0.6020.93
99_P118_T0.6020.93
36_P42_R0.6020.93
20_L157_E0.5980.92
34_S49_A0.5950.92
85_F94_I0.5940.92
72_V84_L0.5930.92
154_I163_A0.5920.92
63_P66_E0.5880.92
36_P49_A0.5880.92
7_H77_L0.5850.92
8_G45_A0.5850.92
95_L137_A0.5820.91
142_M145_P0.5810.91
11_G21_L0.5790.91
145_P150_L0.5770.91
37_I63_P0.5750.91
3_E66_E0.5750.91
93_T141_V0.5720.91
19_Q157_E0.5720.91
16_T20_L0.5710.91
34_S48_E0.5700.90
154_I158_F0.5690.90
97_N116_I0.5670.90
42_R47_I0.5650.90
45_A77_L0.5650.90
34_S51_C0.5620.90
33_S52_R0.5610.90
150_L153_A0.5600.90
5_R62_S0.5580.90
97_N130_V0.5580.90
115_K133_I0.5570.89
17_A135_L0.5570.89
154_I159_D0.5490.89
46_E76_S0.5450.88
39_G42_R0.5430.88
42_R45_A0.5420.88
126_G129_M0.5420.88
151_E154_I0.5410.88
3_E68_D0.5410.88
18_S34_S0.5350.88
19_Q23_E0.5340.87
24_A28_E0.5340.87
31_Y56_T0.5330.87
97_N117_A0.5320.87
159_D162_V0.5320.87
3_E64_V0.5310.87
25_A30_L0.5310.87
27_Y153_A0.5270.87
39_G47_I0.5260.87
122_L128_P0.5240.86
136_G169_G0.5220.86
140_R143_G0.5200.86
6_F73_I0.5160.86
6_F18_S0.5140.85
15_V19_Q0.5120.85
10_G15_V0.5090.85
54_S57_P0.5090.85
125_S129_M0.5070.85
15_V34_S0.5060.85
139_I145_P0.5060.85
3_E67_P0.5050.84
43_R128_P0.5040.84
38_Y44_G0.5020.84
28_E145_P0.5010.84
14_V19_Q0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3on3A 2 0.9402 100 0.141 Contact Map
3g2eA 4 0.9837 100 0.148 Contact Map
2raaA 1 0.9293 100 0.158 Contact Map
2c42A 2 0.9946 100 0.202 Contact Map
5c4iB 1 0.9402 100 0.281 Contact Map
1id1A 2 0.7337 49.4 0.924 Contact Map
1dxyA 5 0.8533 49.2 0.924 Contact Map
4xybA 2 0.8913 47.8 0.924 Contact Map
3gvxA 2 0.8533 44.8 0.926 Contact Map
4n18A 2 0.8696 44.4 0.926 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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