Q97V74 - SULSO - GREMLIN Contacts

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Q97V74 - Carbon monoxide dehydrogenase, large chain (CutA-5)

UniProt:	Q97V74	Sequences: MTVYIGSSVKRVEDLRFLTGKGRYIDDIYLPNMQYMAVLRSNYAWAKFKLDPKRAEERGFNVITFEDTKEFSPLPNFFIPDPKRAPKEYILAKEEAKYFGEPIALVLGRDRYEVYDALELVDVDYEPIEPITDPFKAIEPNSLILHKELGSNIVYSDIFEYGEEPKDYHYVEKTFRYNRILPAPLETNGVIADFDKVSGNLTIYANTQVPQVFKTALSIIFNIPRSKVRIIVPDSGGGFGGKIFLKPLAMTALASILTGRPVKYIETRYEHVISAIHGPDRHYTAKILFKGDEILGAIVDLVEDFGAYLHTYQPLPILRQIYQLVGPYKMKYLKFRVSGVVTNKPPTGAYRGLGIPPAVLVLENLVKSISKVNGIDEIELRTKNFIDKLPYEHITGAIYDSGNYREALKKLISQLEVKDKDKYTGVGIAFALEPGSSLAFQTLVVNKPRTPYYEGVYMRIDSGGDVTVFLSTNTMGTGHETAISQVVADVLGIPIEDVKVILGDTAGPPGTGFYGSRFSVVGISAVYIASLKLKEKMREYLAKMFNVEKDDVKIDNGTVKIGNRSINVKEAVNMIYNRSYLIGDEIGLDVSVTINSYNVNIADEKRRVNFSTTYGVNAHGIVIRVDKDTGFIKILKYVILSDCGTMINPMIVDGQLMGGTTMGIGASLLEKVEYDENGIPKQTSFADYWIPSAEEVPNFEIQHMINPSPFTPLGTKGVAEGGATVPPAAIINALEDIVKKPINRVEIPITPEYVLQLINDMS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	762 (716)
Sequences:	5338 (3505)
Seq/√Len:	131.0

ECOLI - XDHD XDHA YAGR
BACSU - XDHD
SULSO - Q97V74 Q7LX54 Q97VI4 Q97UK2 Q97TZ2 Q7LXA2 Q97YU6 Q97UR0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
172_E	286_K	4.368	1.00
39_L	121_V	4.231	1.00
110_D	113_E	3.903	1.00
382_T	409_K	3.723	1.00
54_R	122_D	3.683	1.00
174_T	284_T	3.666	1.00
43_Y	46_A	3.646	1.00
416_E	419_D	3.589	1.00
290_K	293_E	3.501	1.00
289_F	369_I	3.452	1.00
298_I	334_K	3.425	1.00
168_Y	291_G	3.256	1.00
487_V	526_V	3.248	1.00
375_I	383_K	3.199	1.00
47_K	126_E	3.197	1.00
168_Y	290_K	3.181	1.00
34_Q	60_F	3.170	1.00
294_I	366_V	3.067	1.00
162_G	166_K	3.065	1.00
39_L	118_L	3.048	1.00
466_V	493_I	3.047	1.00
159_F	162_G	3.033	1.00
172_E	284_T	2.944	1.00
490_V	531_L	2.865	1.00
46_A	125_Y	2.862	1.00
300_D	336_R	2.837	1.00
43_Y	127_P	2.823	1.00
329_K	390_P	2.750	1.00
379_E	383_K	2.748	1.00
45_W	128_I	2.731	1.00
49_K	124_D	2.721	1.00
558_T	565_S	2.711	1.00
203_I	217_L	2.674	1.00
286_K	298_I	2.664	1.00
107_L	254_A	2.640	1.00
109_R	113_E	2.563	1.00
527_Y	531_L	2.504	1.00
636_K	700_E	2.500	1.00
731_I	749_I	2.470	1.00
567_N	570_E	2.463	1.00
202_T	231_I	2.443	1.00
293_E	383_K	2.435	1.00
746_E	753_Y	2.354	1.00
432_L	624_R	2.340	1.00
135_F	282_H	2.337	1.00
36_M	264_Y	2.335	1.00
193_D	204_Y	2.310	1.00
375_I	380_L	2.308	1.00
109_R	260_R	2.297	1.00
200_N	506_A	2.291	1.00
734_L	749_I	2.275	1.00
52_P	56_E	2.253	1.00
300_D	338_S	2.245	1.00
61_N	109_R	2.224	1.00
415_L	620_G	2.216	1.00
624_R	635_L	2.208	1.00
304_D	344_K	2.195	1.00
229_R	504_D	2.185	1.00
164_E	288_L	2.183	1.00
369_I	380_L	2.177	1.00
167_D	288_L	2.133	1.00
136_K	139_E	2.109	1.00
38_V	250_M	2.098	1.00
410_K	702_Q	2.090	1.00
410_K	413_S	2.073	1.00
379_E	382_T	2.066	1.00
465_D	497_D	2.051	1.00
287_I	365_L	2.048	1.00
382_T	412_I	2.022	1.00
36_M	105_L	2.018	1.00
42_N	103_I	2.013	1.00
411_L	620_G	2.009	1.00
460_I	533_L	2.007	1.00
660_T	699_F	2.003	1.00
169_H	289_F	1.992	1.00
169_H	291_G	1.974	1.00
52_P	62_V	1.969	1.00
409_K	413_S	1.949	1.00
661_T	696_V	1.946	1.00
34_Q	61_N	1.936	1.00
293_E	329_K	1.935	1.00
176_R	746_E	1.925	1.00
285_A	365_L	1.919	1.00
621_I	729_A	1.914	1.00
534_K	538_R	1.909	1.00
9_V	495_I	1.898	1.00
47_K	94_E	1.869	1.00
51_D	122_D	1.867	1.00
387_D	390_P	1.860	1.00
378_I	412_I	1.860	1.00
107_L	258_T	1.853	1.00
458_M	468_V	1.851	1.00
465_D	499_K	1.844	1.00
484_S	500_V	1.830	1.00
53_K	56_E	1.822	1.00
54_R	120_L	1.819	1.00
26_D	263_K	1.819	1.00
47_K	95_E	1.818	1.00
519_S	647_I	1.814	1.00
461_D	467_T	1.805	1.00
387_D	405_R	1.797	1.00
108_G	114_V	1.792	1.00
494_P	497_D	1.778	1.00
105_L	254_A	1.772	1.00
200_N	227_K	1.767	1.00
133_D	136_K	1.760	1.00
43_Y	125_Y	1.759	1.00
486_V	523_I	1.754	1.00
55_A	121_V	1.746	1.00
548_E	551_D	1.724	1.00
434_P	624_R	1.723	1.00
36_M	262_V	1.722	1.00
189_G	265_I	1.706	1.00
414_Q	700_E	1.705	1.00
183_A	685_F	1.701	1.00
290_K	295_L	1.686	1.00
10_K	650_M	1.678	1.00
632_I	754_V	1.672	1.00
652_V	718_V	1.671	1.00
645_T	705_I	1.665	1.00
164_E	286_K	1.648	1.00
461_D	465_D	1.645	1.00
371_K	735_E	1.642	1.00
431_A	626_D	1.640	1.00
410_K	414_Q	1.631	1.00
118_L	121_V	1.630	1.00
287_I	369_I	1.629	1.00
466_V	491_L	1.620	1.00
456_V	526_V	1.619	1.00
750_T	753_Y	1.619	1.00
441_Q	617_N	1.615	1.00
184_P	241_G	1.610	1.00
54_R	57_E	1.608	1.00
403_N	406_E	1.601	1.00
174_T	282_H	1.600	1.00
458_M	530_S	1.597	1.00
619_H	637_Y	1.592	1.00
195_D	198_S	1.587	1.00
45_W	95_E	1.587	1.00
468_V	487_V	1.584	1.00
637_Y	660_T	1.584	1.00
646_M	703_H	1.579	1.00
105_L	250_M	1.572	1.00
287_I	294_I	1.560	1.00
169_H	372_V	1.556	1.00
555_D	560_K	1.553	1.00
433_E	627_K	1.552	1.00
25_I	189_G	1.552	1.00
30_L	33_M	1.544	1.00
532_K	590_V	1.542	1.00
167_D	295_L	1.541	1.00
405_R	409_K	1.536	1.00
552_V	559_V	1.525	1.00
284_T	300_D	1.517	1.00
652_V	703_H	1.510	1.00
202_T	229_R	1.505	1.00
621_I	637_Y	1.502	1.00
643_C	646_M	1.500	1.00
161_Y	334_K	1.485	1.00
538_R	552_V	1.485	1.00
431_A	627_K	1.484	1.00
414_Q	702_Q	1.481	1.00
490_V	713_L	1.476	1.00
412_I	418_K	1.476	1.00
632_I	734_L	1.471	1.00
30_L	193_D	1.470	1.00
170_Y	286_K	1.464	1.00
169_H	290_K	1.452	1.00
169_H	369_I	1.446	1.00
66_E	94_E	1.446	1.00
497_D	569_K	1.443	1.00
61_N	260_R	1.439	1.00
382_T	405_R	1.438	1.00
116_D	120_L	1.434	1.00
95_E	147_K	1.434	1.00
223_I	228_V	1.431	1.00
636_K	698_N	1.430	1.00
411_L	618_A	1.428	1.00
161_Y	165_P	1.421	1.00
663_G	726_P	1.419	1.00
553_K	560_K	1.412	1.00
634_I	664_I	1.412	1.00
490_V	527_Y	1.407	1.00
38_V	264_Y	1.402	1.00
61_N	257_L	1.394	1.00
367_K	732_N	1.393	1.00
528_I	532_K	1.390	1.00
163_E	296_G	1.390	1.00
305_F	313_Q	1.383	1.00
371_K	736_D	1.383	1.00
169_H	373_N	1.382	1.00
63_I	254_A	1.381	1.00
294_I	330_M	1.375	1.00
217_L	228_V	1.375	1.00
164_E	296_G	1.373	1.00
113_E	117_A	1.366	1.00
63_I	258_T	1.363	1.00
218_S	228_V	1.359	1.00
292_D	383_K	1.358	1.00
432_L	633_K	1.356	1.00
26_D	265_I	1.355	1.00
34_Q	260_R	1.348	1.00
176_R	282_H	1.346	1.00
482_A	519_S	1.344	1.00
532_K	535_E	1.340	1.00
33_M	263_K	1.339	1.00
488_A	498_V	1.339	1.00
547_V	561_I	1.337	1.00
48_F	123_V	1.332	1.00
289_F	373_N	1.330	1.00
160_E	164_E	1.329	1.00
539_E	549_K	1.324	1.00
192_A	203_I	1.324	1.00
221_F	252_A	1.323	1.00
156_S	336_R	1.315	1.00
363_E	381_R	1.313	1.00
431_A	628_D	1.309	1.00
30_L	191_I	1.308	1.00
486_V	519_S	1.306	1.00
541_L	571_A	1.304	1.00
350_Y	662_M	1.303	1.00
367_K	377_E	1.302	1.00
199_G	227_K	1.300	1.00
483_I	526_V	1.294	1.00
407_A	618_A	1.294	1.00
173_K	368_S	1.294	1.00
373_N	380_L	1.292	1.00
224_P	227_K	1.291	1.00
638_V	700_E	1.284	1.00
414_Q	640_L	1.284	1.00
415_L	638_V	1.268	1.00
432_L	626_D	1.265	1.00
201_L	223_I	1.263	1.00
163_E	332_Y	1.260	1.00
215_T	225_R	1.258	1.00
254_A	262_V	1.257	1.00
95_E	128_I	1.257	1.00
22_G	234_D	1.253	1.00
646_M	652_V	1.249	1.00
103_I	123_V	1.248	1.00
283_Y	361_V	1.240	1.00
156_S	334_K	1.236	1.00
276_I	348_G	1.235	1.00
65_F	93_K	1.234	1.00
37_A	118_L	1.234	1.00
192_A	251_T	1.234	1.00
192_A	255_S	1.231	1.00
665_G	691_P	1.226	1.00
201_L	252_A	1.226	1.00
280_D	304_D	1.224	1.00
547_V	551_D	1.224	1.00
625_V	632_I	1.218	1.00
656_L	660_T	1.214	1.00
630_G	754_V	1.213	1.00
160_E	163_E	1.212	1.00
623_I	734_L	1.212	1.00
411_L	640_L	1.206	0.99
673_E	682_Q	1.205	0.99
164_E	170_Y	1.199	0.99
56_E	61_N	1.199	0.99
161_Y	298_I	1.198	0.99
37_A	111_R	1.197	0.99
183_A	690_I	1.196	0.99
385_F	408_L	1.186	0.99
42_N	125_Y	1.184	0.99
12_V	484_S	1.179	0.99
173_K	372_V	1.178	0.99
413_S	418_K	1.178	0.99
97_K	101_E	1.177	0.99
640_L	702_Q	1.177	0.99
360_L	731_I	1.175	0.99
45_W	129_E	1.175	0.99
40_R	270_E	1.175	0.99
16_R	21_K	1.168	0.99
632_I	668_L	1.166	0.99
47_K	128_I	1.161	0.99
289_F	380_L	1.159	0.99
37_A	115_Y	1.156	0.99
12_V	481_T	1.155	0.99
302_V	338_S	1.154	0.99
742_I	749_I	1.152	0.99
560_K	565_S	1.143	0.99
379_E	418_K	1.140	0.99
497_D	557_G	1.139	0.99
45_W	343_N	1.139	0.99
204_Y	231_I	1.138	0.99
15_L	19_T	1.137	0.99
421_D	424_T	1.131	0.99
37_A	114_V	1.130	0.99
532_K	536_K	1.129	0.99
485_Q	648_N	1.127	0.99
29_Y	33_M	1.127	0.99
33_M	191_I	1.126	0.99
378_I	438_L	1.126	0.99
524_S	527_Y	1.124	0.99
457_Y	469_F	1.117	0.99
49_K	122_D	1.115	0.99
551_D	561_I	1.115	0.99
484_S	495_I	1.114	0.99
117_A	120_L	1.103	0.99
146_H	341_V	1.101	0.99
287_I	297_A	1.099	0.99
410_K	640_L	1.099	0.99
368_S	743_N	1.096	0.99
434_P	622_V	1.095	0.99
135_F	176_R	1.095	0.99
289_F	294_I	1.092	0.99
621_I	634_I	1.090	0.99
50_L	123_V	1.090	0.99
194_F	256_I	1.088	0.99
538_R	554_I	1.087	0.99
434_P	635_L	1.087	0.99
195_D	202_T	1.086	0.99
487_V	530_S	1.086	0.99
288_L	295_L	1.080	0.99
406_E	410_K	1.080	0.99
38_V	105_L	1.078	0.99
675_D	679_I	1.072	0.99
103_I	125_Y	1.072	0.99
163_E	288_L	1.068	0.99
674_Y	680_P	1.068	0.99
184_P	271_H	1.067	0.99
407_A	640_L	1.067	0.99
752_E	756_Q	1.067	0.99
162_G	165_P	1.058	0.99
642_D	706_N	1.057	0.99
621_I	730_I	1.052	0.99
469_F	501_I	1.049	0.99
537_M	571_A	1.049	0.99
551_D	562_G	1.046	0.99
171_V	372_V	1.045	0.99
111_R	115_Y	1.045	0.99
420_K	622_V	1.044	0.99
468_V	498_V	1.044	0.99
166_K	295_L	1.041	0.98
48_F	103_I	1.041	0.98
190_V	251_T	1.040	0.98
34_Q	258_T	1.040	0.98
535_E	539_E	1.039	0.98
540_Y	571_A	1.039	0.98
421_D	736_D	1.038	0.98
58_R	109_R	1.036	0.98
195_D	200_N	1.035	0.98
288_L	296_G	1.035	0.98
467_T	501_I	1.035	0.98
138_I	340_V	1.035	0.98
91_L	250_M	1.034	0.98
366_V	380_L	1.032	0.98
166_K	290_K	1.031	0.98
138_I	153_I	1.030	0.98
238_G	475_M	1.026	0.98
32_N	260_R	1.026	0.98
171_V	289_F	1.026	0.98
96_A	125_Y	1.025	0.98
668_L	730_I	1.023	0.98
406_E	704_M	1.021	0.98
64_T	91_L	1.019	0.98
554_I	559_V	1.017	0.98
749_I	753_Y	1.017	0.98
50_L	121_V	1.012	0.98
194_F	255_S	1.008	0.98
68_T	253_L	1.005	0.98
671_K	753_Y	0.998	0.98
546_N	551_D	0.997	0.98
175_F	365_L	0.995	0.98
235_S	475_M	0.993	0.98
490_V	530_S	0.992	0.98
181_L	672_V	0.992	0.98
385_F	405_R	0.990	0.98
46_A	128_I	0.985	0.98
531_L	535_E	0.982	0.98
63_I	257_L	0.980	0.98
134_P	302_V	0.979	0.98
669_L	695_E	0.979	0.98
46_A	123_V	0.976	0.98
544_M	574_M	0.974	0.98
321_I	335_F	0.972	0.98
749_I	754_V	0.971	0.98
481_T	485_Q	0.969	0.98
206_N	242_K	0.966	0.98
168_Y	295_L	0.963	0.97
279_P	357_P	0.962	0.97
371_K	739_K	0.960	0.97
63_I	107_L	0.959	0.97
160_E	298_I	0.958	0.97
182_P	241_G	0.958	0.97
193_D	202_T	0.958	0.97
106_V	118_L	0.955	0.97
664_I	696_V	0.952	0.97
223_I	256_I	0.950	0.97
164_E	298_I	0.948	0.97
367_K	381_R	0.948	0.97
566_I	574_M	0.948	0.97
171_V	287_I	0.946	0.97
490_V	534_K	0.944	0.97
65_F	94_E	0.944	0.97
684_S	687_D	0.943	0.97
302_V	340_V	0.940	0.97
138_I	302_V	0.939	0.97
460_I	568_V	0.937	0.97
104_A	121_V	0.934	0.97
45_W	130_P	0.933	0.97
487_V	498_V	0.929	0.97
422_K	425_G	0.929	0.97
36_M	254_A	0.929	0.97
193_D	255_S	0.926	0.97
251_T	264_Y	0.926	0.97
8_S	653_D	0.924	0.97
653_D	657_M	0.924	0.97
317_I	337_V	0.923	0.97
535_E	549_K	0.923	0.97
281_R	320_Q	0.919	0.97
214_K	225_R	0.914	0.97
472_T	518_F	0.914	0.97
208_Q	238_G	0.911	0.96
478_G	651_I	0.911	0.96
131_I	137_A	0.910	0.96
534_K	554_I	0.909	0.96
528_I	592_V	0.908	0.96
623_I	634_I	0.908	0.96
378_I	408_L	0.906	0.96
228_V	252_A	0.905	0.96
63_I	253_L	0.904	0.96
269_Y	683_T	0.901	0.96
540_Y	575_I	0.900	0.96
328_Y	363_E	0.896	0.96
653_D	703_H	0.892	0.96
286_K	334_K	0.892	0.96
35_Y	263_K	0.892	0.96
432_L	627_K	0.891	0.96
160_E	332_Y	0.891	0.96
408_L	438_L	0.891	0.96
570_E	573_N	0.889	0.96
457_Y	591_S	0.886	0.96
406_E	409_K	0.886	0.96
163_E	295_L	0.885	0.96
485_Q	649_P	0.884	0.96
16_R	480_E	0.882	0.96
38_V	102_P	0.881	0.96
422_K	426_V	0.881	0.96
229_R	506_A	0.879	0.96
223_I	227_K	0.878	0.96
546_N	561_I	0.878	0.96
459_R	469_F	0.878	0.96
134_P	282_H	0.878	0.96
467_T	499_K	0.875	0.96
328_Y	381_R	0.874	0.96
135_F	174_T	0.872	0.95
62_V	104_A	0.870	0.95
104_A	123_V	0.870	0.95
160_E	296_G	0.870	0.95
472_T	479_H	0.870	0.95
537_M	575_I	0.868	0.95
639_I	660_T	0.866	0.95
48_F	125_Y	0.866	0.95
537_M	568_V	0.861	0.95
139_E	142_S	0.861	0.95
243_I	514_Y	0.861	0.95
423_Y	426_V	0.860	0.95
408_L	440_F	0.859	0.95
101_E	308_Y	0.855	0.95
160_E	334_K	0.853	0.95
39_L	104_A	0.852	0.95
52_P	121_V	0.852	0.95
680_P	683_T	0.850	0.95
201_L	256_I	0.850	0.95
298_I	336_R	0.850	0.95
194_F	199_G	0.847	0.95
170_Y	288_L	0.839	0.94
532_K	592_V	0.839	0.94
175_F	368_S	0.838	0.94
206_N	235_S	0.835	0.94
167_D	296_G	0.834	0.94
114_V	118_L	0.832	0.94
16_R	234_D	0.831	0.94
17_F	24_Y	0.831	0.94
281_R	303_E	0.831	0.94
566_I	571_A	0.831	0.94
52_P	55_A	0.830	0.94
392_E	398_I	0.829	0.94
52_P	64_T	0.829	0.94
528_I	531_L	0.829	0.94
108_G	117_A	0.827	0.94
477_T	513_F	0.826	0.94
643_C	652_V	0.825	0.94
40_R	274_S	0.821	0.94
430_F	433_E	0.820	0.94
289_F	365_L	0.820	0.94
533_L	588_L	0.820	0.94
558_T	567_N	0.820	0.94
132_T	678_G	0.818	0.94
622_V	636_K	0.818	0.94
39_L	123_V	0.818	0.94
25_I	28_I	0.818	0.94
364_N	731_I	0.817	0.94
59_G	117_A	0.817	0.94
53_K	57_E	0.816	0.94
159_F	332_Y	0.815	0.94
164_E	167_D	0.814	0.94
46_A	96_A	0.813	0.93
360_L	364_N	0.812	0.93
67_D	257_L	0.812	0.93
738_V	757_L	0.811	0.93
445_V	613_T	0.810	0.93
92_A	96_A	0.810	0.93
50_L	103_I	0.809	0.93
163_E	167_D	0.806	0.93
460_I	537_M	0.805	0.93
663_G	723_A	0.805	0.93
486_V	647_I	0.805	0.93
43_Y	96_A	0.804	0.93
30_L	204_Y	0.803	0.93
283_Y	299_V	0.803	0.93
56_E	66_E	0.802	0.93
735_E	741_P	0.801	0.93
417_V	420_K	0.800	0.93
675_D	681_K	0.800	0.93
417_V	438_L	0.799	0.93
188_N	271_H	0.798	0.93
266_E	271_H	0.798	0.93
56_E	67_D	0.796	0.93
205_A	213_F	0.796	0.93
362_L	365_L	0.793	0.93
458_M	533_L	0.790	0.92
285_A	361_V	0.789	0.92
454_E	522_G	0.788	0.92
625_V	754_V	0.786	0.92
711_T	715_T	0.786	0.92
9_V	484_S	0.785	0.92
5_I	489_D	0.785	0.92
466_V	533_L	0.784	0.92
113_E	116_D	0.784	0.92
187_T	265_I	0.783	0.92
158_I	163_E	0.782	0.92
440_F	618_A	0.782	0.92
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129_E	136_K	0.780	0.92
131_I	343_N	0.780	0.92
619_H	725_V	0.780	0.92
295_L	332_Y	0.779	0.92
214_K	505_T	0.779	0.92
172_E	298_I	0.779	0.92
559_V	571_A	0.776	0.92
115_Y	267_T	0.776	0.92
685_F	690_I	0.775	0.92
412_I	417_V	0.774	0.92
468_V	526_V	0.773	0.92
375_I	379_E	0.773	0.92
489_D	645_T	0.772	0.92
723_A	727_P	0.772	0.92
643_C	718_V	0.772	0.92
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754_V	757_L	0.770	0.91
380_L	383_K	0.770	0.91
487_V	490_V	0.770	0.91
307_A	343_N	0.769	0.91
623_I	632_I	0.769	0.91
360_L	747_I	0.767	0.91
133_D	282_H	0.767	0.91
482_A	651_I	0.767	0.91
672_V	680_P	0.766	0.91
254_A	258_T	0.762	0.91
696_V	699_F	0.761	0.91
142_S	145_L	0.760	0.91
135_F	302_V	0.760	0.91
210_P	505_T	0.759	0.91
207_T	213_F	0.759	0.91
458_M	529_A	0.758	0.91
66_E	93_K	0.758	0.91
140_P	143_L	0.756	0.91
530_S	533_L	0.756	0.91
297_A	330_M	0.756	0.91
211_Q	505_T	0.755	0.91
163_E	166_K	0.753	0.91
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494_P	557_G	0.752	0.91
12_V	495_I	0.750	0.90
637_Y	726_P	0.749	0.90
626_D	631_F	0.749	0.90
460_I	466_V	0.747	0.90
191_I	263_K	0.746	0.90
199_G	256_I	0.746	0.90
458_M	487_V	0.746	0.90
365_L	369_I	0.746	0.90
403_N	704_M	0.745	0.90
482_A	647_I	0.745	0.90
112_Y	116_D	0.745	0.90
493_I	497_D	0.745	0.90
194_F	201_L	0.744	0.90
637_Y	699_F	0.744	0.90
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433_E	625_V	0.743	0.90
175_F	364_N	0.743	0.90
641_S	656_L	0.743	0.90
294_I	380_L	0.743	0.90
529_A	592_V	0.742	0.90
229_R	505_T	0.742	0.90
45_W	145_L	0.742	0.90
306_G	346_P	0.741	0.90
152_N	155_Y	0.741	0.90
175_F	743_N	0.740	0.90
28_I	204_Y	0.740	0.90
180_I	666_A	0.740	0.90
376_D	417_V	0.739	0.90
97_K	308_Y	0.738	0.90
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365_L	368_S	0.735	0.90
313_Q	339_G	0.735	0.90
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560_K	563_N	0.733	0.89
205_A	248_L	0.731	0.89
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267_T	270_E	0.727	0.89
537_M	559_V	0.726	0.89
325_V	333_L	0.726	0.89
545_F	566_I	0.725	0.89
111_R	267_T	0.725	0.89
538_R	559_V	0.724	0.89
571_A	575_I	0.724	0.89
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137_A	142_S	0.717	0.88
213_F	217_L	0.716	0.88
732_N	741_P	0.716	0.88
51_D	55_A	0.714	0.88
157_D	333_L	0.714	0.88
623_I	733_A	0.714	0.88
619_H	726_P	0.714	0.88
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164_E	295_L	0.712	0.88
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419_D	422_K	0.712	0.88
368_S	372_V	0.711	0.88
524_S	711_T	0.711	0.88
221_F	253_L	0.711	0.88
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138_I	338_S	0.709	0.88
581_L	588_L	0.708	0.88
117_A	121_V	0.708	0.88
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135_F	139_E	0.707	0.88
538_R	549_K	0.707	0.88
439_A	729_A	0.705	0.87
156_S	338_S	0.704	0.87
176_R	280_D	0.703	0.87
141_N	144_I	0.702	0.87
168_Y	293_E	0.702	0.87
540_Y	578_R	0.701	0.87
576_Y	579_S	0.700	0.87
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11_R	17_F	0.699	0.87
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159_F	163_E	0.697	0.87
172_E	372_V	0.697	0.87
43_Y	103_I	0.696	0.87
568_V	572_V	0.695	0.87
258_T	262_V	0.694	0.87
44_A	99_F	0.693	0.87
385_F	402_G	0.693	0.87
214_K	506_A	0.693	0.87
664_I	730_I	0.692	0.87
190_V	205_A	0.691	0.86
301_L	320_Q	0.690	0.86
535_E	538_R	0.689	0.86
638_V	702_Q	0.689	0.86
55_A	59_G	0.688	0.86
446_N	521_V	0.687	0.86
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429_A	433_E	0.687	0.86
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545_F	552_V	0.685	0.86
463_G	499_K	0.685	0.86
412_I	620_G	0.684	0.86
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220_I	249_A	0.684	0.86
742_I	757_L	0.682	0.86
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305_F	339_G	0.676	0.85
59_G	109_R	0.676	0.85
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89_Y	93_K	0.674	0.85
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116_D	119_E	0.673	0.85
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320_Q	358_A	0.671	0.85
49_K	53_K	0.670	0.85
427_G	434_P	0.670	0.85
29_Y	263_K	0.670	0.85
536_K	539_E	0.669	0.85
526_V	530_S	0.668	0.85
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23_R	28_I	0.666	0.84
413_S	416_E	0.664	0.84
113_E	120_L	0.664	0.84
39_L	42_N	0.664	0.84
107_L	262_V	0.663	0.84
541_L	544_M	0.662	0.84
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145_L	343_N	0.661	0.84
492_G	534_K	0.660	0.84
288_L	298_I	0.660	0.84
511_T	514_Y	0.660	0.84
303_E	339_G	0.659	0.84
407_A	704_M	0.659	0.84
544_M	566_I	0.658	0.84
653_D	701_I	0.658	0.84
304_D	342_T	0.658	0.84
385_F	440_F	0.657	0.84
642_D	707_P	0.657	0.84
287_I	380_L	0.656	0.83
501_I	507_G	0.655	0.83
620_G	638_V	0.654	0.83
173_K	743_N	0.653	0.83
418_K	422_K	0.653	0.83
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417_V	436_S	0.652	0.83
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479_H	518_F	0.651	0.83
297_A	365_L	0.651	0.83
485_Q	489_D	0.650	0.83
290_K	383_K	0.650	0.83
41_S	99_F	0.649	0.83
19_T	22_G	0.649	0.83
33_M	261_P	0.648	0.83
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513_F	518_F	0.645	0.82
188_N	241_G	0.644	0.82
738_V	754_V	0.643	0.82
657_M	701_I	0.643	0.82
673_E	681_K	0.642	0.82
209_V	514_Y	0.642	0.82
669_L	689_W	0.642	0.82
296_G	332_Y	0.640	0.82
344_K	674_Y	0.639	0.82
452_Y	517_R	0.638	0.82
539_E	543_K	0.638	0.82
183_A	672_V	0.638	0.82
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333_L	394_I	0.637	0.82
555_D	558_T	0.637	0.82
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656_L	701_I	0.634	0.81
28_I	233_P	0.632	0.81
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485_Q	495_I	0.629	0.81
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491_L	530_S	0.628	0.81
67_D	70_E	0.628	0.81
32_N	261_P	0.626	0.81
271_H	275_A	0.626	0.81
132_T	344_K	0.626	0.81
14_D	17_F	0.624	0.80
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533_L	590_V	0.624	0.80
28_I	191_I	0.624	0.80
355_I	443_L	0.623	0.80
589_D	592_V	0.622	0.80
492_G	554_I	0.621	0.80
177_Y	666_A	0.621	0.80
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415_L	436_S	0.620	0.80
429_A	627_K	0.620	0.80
329_K	387_D	0.620	0.80
416_E	636_K	0.620	0.80
282_H	302_V	0.620	0.80
171_V	380_L	0.619	0.80
411_L	638_V	0.619	0.80
538_R	542_A	0.619	0.80
436_S	736_D	0.618	0.80
368_S	741_P	0.618	0.80
177_Y	360_L	0.618	0.80
475_M	513_F	0.617	0.80
561_I	564_R	0.617	0.80
103_I	121_V	0.616	0.79
330_M	333_L	0.615	0.79
377_E	732_N	0.614	0.79
546_N	552_V	0.614	0.79
317_I	339_G	0.613	0.79
48_F	92_A	0.613	0.79
23_R	29_Y	0.612	0.79
541_L	552_V	0.612	0.79
65_F	69_K	0.612	0.79
52_P	66_E	0.612	0.79
359_V	724_T	0.611	0.79
297_A	362_L	0.610	0.79
454_E	510_G	0.610	0.79
739_K	742_I	0.609	0.79
299_V	361_V	0.608	0.79
435_G	736_D	0.608	0.79
285_A	369_I	0.607	0.78
106_V	121_V	0.606	0.78
55_A	117_A	0.605	0.78
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420_K	424_T	0.604	0.78
364_N	735_E	0.602	0.78
536_K	590_V	0.602	0.78
194_F	200_N	0.602	0.78
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430_F	627_K	0.601	0.78
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518_F	522_G	0.600	0.78
95_E	145_L	0.599	0.78
470_L	483_I	0.597	0.77
217_L	245_L	0.597	0.77
625_V	630_G	0.597	0.77
491_L	498_V	0.596	0.77
256_I	259_G	0.596	0.77
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364_N	741_P	0.594	0.77
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419_D	423_Y	0.594	0.77
646_M	649_P	0.594	0.77
429_A	624_R	0.594	0.77
213_F	248_L	0.594	0.77
435_G	625_V	0.594	0.77
554_I	568_V	0.592	0.77
574_M	578_R	0.592	0.77
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58_R	113_E	0.590	0.77
146_H	308_Y	0.590	0.77
214_K	218_S	0.590	0.77
546_N	562_G	0.590	0.77
144_I	148_E	0.588	0.76
558_T	570_E	0.587	0.76
483_I	487_V	0.587	0.76
179_R	672_V	0.587	0.76
581_L	589_D	0.586	0.76
163_E	168_Y	0.586	0.76
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192_A	262_V	0.586	0.76
89_Y	92_A	0.585	0.76
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295_L	380_L	0.583	0.76
626_D	629_T	0.582	0.76
386_I	402_G	0.582	0.76
432_L	635_L	0.581	0.75
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48_F	65_F	0.581	0.75
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369_I	375_I	0.580	0.75
162_G	332_Y	0.580	0.75
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373_N	383_K	0.578	0.75
280_D	347_T	0.578	0.75
566_I	570_E	0.577	0.75
127_P	130_P	0.577	0.75
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519_S	715_T	0.576	0.75
388_K	405_R	0.575	0.75
319_R	323_Q	0.575	0.75
554_I	558_T	0.574	0.75
590_V	593_T	0.574	0.75
374_G	377_E	0.574	0.75
634_I	730_I	0.573	0.74
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153_I	338_S	0.572	0.74
136_K	676_E	0.572	0.74
581_L	591_S	0.572	0.74
124_D	127_P	0.572	0.74
419_D	426_V	0.571	0.74
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309_L	341_V	0.570	0.74
439_A	732_N	0.570	0.74
474_T	480_E	0.570	0.74
662_M	665_G	0.569	0.74
420_K	636_K	0.569	0.74
461_D	499_K	0.568	0.74
323_Q	444_V	0.568	0.74
689_W	692_S	0.568	0.74
572_V	580_Y	0.568	0.74
369_I	372_V	0.567	0.74
564_R	570_E	0.566	0.74
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59_G	108_G	0.566	0.74
163_E	331_K	0.566	0.74
634_I	637_Y	0.565	0.73
639_I	656_L	0.565	0.73
353_L	515_G	0.565	0.73
303_E	317_I	0.565	0.73
540_Y	544_M	0.563	0.73
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458_M	466_V	0.562	0.73
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427_G	736_D	0.562	0.73
510_G	522_G	0.561	0.73
753_Y	756_Q	0.561	0.73
299_V	324_L	0.561	0.73
547_V	552_V	0.559	0.73
574_M	577_N	0.559	0.73
442_T	614_Y	0.559	0.73
543_K	578_R	0.558	0.72
91_L	102_P	0.558	0.72
280_D	344_K	0.558	0.72
656_L	722_G	0.558	0.72
312_Y	353_L	0.558	0.72
177_Y	283_Y	0.557	0.72
49_K	291_G	0.557	0.72
483_I	500_V	0.557	0.72
286_K	300_D	0.557	0.72
420_K	423_Y	0.556	0.72
41_S	103_I	0.554	0.72
297_A	324_L	0.553	0.72
589_D	593_T	0.553	0.72
6_G	485_Q	0.552	0.72
303_E	320_Q	0.552	0.72
272_V	685_F	0.552	0.72
428_I	433_E	0.551	0.72
180_I	278_G	0.551	0.72
57_E	122_D	0.550	0.71
433_E	738_V	0.550	0.71
656_L	703_H	0.550	0.71
57_E	113_E	0.550	0.71
717_G	722_G	0.550	0.71
426_V	430_F	0.549	0.71
16_R	198_S	0.549	0.71
377_E	381_R	0.548	0.71
5_I	647_I	0.548	0.71
493_I	498_V	0.548	0.71
411_L	415_L	0.548	0.71
48_F	55_A	0.548	0.71
131_I	143_L	0.548	0.71
480_E	502_L	0.548	0.71
42_N	46_A	0.548	0.71
88_E	101_E	0.548	0.71
143_L	146_H	0.548	0.71
190_V	247_P	0.547	0.71
540_Y	543_K	0.547	0.71
424_T	428_I	0.547	0.71
295_L	331_K	0.547	0.71
753_Y	757_L	0.546	0.71
553_K	562_G	0.546	0.71
366_V	373_N	0.545	0.71
60_F	108_G	0.545	0.71
542_A	549_K	0.545	0.71
475_M	479_H	0.545	0.71
462_S	573_N	0.545	0.71
572_V	575_I	0.544	0.71
266_E	275_A	0.544	0.71
209_V	212_V	0.544	0.71
171_V	373_N	0.544	0.71
385_F	404_Y	0.543	0.70
45_W	96_A	0.542	0.70
293_E	331_K	0.541	0.70
429_A	434_P	0.541	0.70
34_Q	262_V	0.541	0.70
661_T	664_I	0.540	0.70
216_A	245_L	0.540	0.70
188_N	275_A	0.539	0.70
433_E	740_K	0.539	0.70
40_R	102_P	0.538	0.70
99_F	680_P	0.538	0.70
403_N	706_N	0.538	0.70
458_M	526_V	0.538	0.70
544_M	571_A	0.537	0.70
438_L	620_G	0.537	0.70
55_A	104_A	0.537	0.70
206_N	238_G	0.536	0.69
645_T	707_P	0.535	0.69
520_V	710_F	0.534	0.69
617_N	641_S	0.534	0.69
367_K	741_P	0.534	0.69
204_Y	233_P	0.534	0.69
664_I	669_L	0.534	0.69
210_P	473_N	0.534	0.69
108_G	113_E	0.533	0.69
43_Y	123_V	0.533	0.69
289_F	372_V	0.533	0.69
571_A	574_M	0.533	0.69
312_Y	315_L	0.532	0.69
445_V	520_V	0.532	0.69
59_G	113_E	0.531	0.69
454_E	525_A	0.531	0.69
399_Y	616_V	0.530	0.69
168_Y	292_D	0.528	0.68
458_M	498_V	0.528	0.68
401_S	616_V	0.528	0.68
393_H	399_Y	0.527	0.68
62_V	106_V	0.526	0.68
231_I	504_D	0.526	0.68
401_S	716_K	0.526	0.68
382_T	408_L	0.526	0.68
35_Y	110_D	0.525	0.68
454_E	521_V	0.524	0.68
574_M	580_Y	0.524	0.68
133_D	340_V	0.523	0.68
350_Y	723_A	0.523	0.68
505_T	509_P	0.523	0.68
106_V	114_V	0.522	0.67
479_H	513_F	0.522	0.67
118_L	122_D	0.522	0.67
253_L	258_T	0.522	0.67
483_I	486_V	0.521	0.67
455_G	508_P	0.520	0.67
573_N	577_N	0.520	0.67
210_P	510_G	0.519	0.67
183_A	272_V	0.518	0.67
415_L	618_A	0.518	0.67
88_E	92_A	0.518	0.67
55_A	60_F	0.518	0.67
131_I	136_K	0.518	0.67
105_L	264_Y	0.518	0.67
552_V	561_I	0.518	0.67
38_V	251_T	0.517	0.67
400_D	609_N	0.516	0.67
203_I	252_A	0.516	0.67
548_E	561_I	0.516	0.67
393_H	614_Y	0.515	0.66
235_S	473_N	0.515	0.66
657_M	699_F	0.515	0.66
420_K	436_S	0.515	0.66
191_I	204_Y	0.514	0.66
134_P	340_V	0.513	0.66
364_N	732_N	0.513	0.66
542_A	545_F	0.513	0.66
377_E	421_D	0.513	0.66
542_A	574_M	0.513	0.66
324_L	335_F	0.512	0.66
180_I	350_Y	0.512	0.66
9_V	485_Q	0.512	0.66
42_N	96_A	0.511	0.66
55_A	120_L	0.511	0.66
575_I	580_Y	0.511	0.66
379_E	412_I	0.511	0.66
619_H	639_I	0.510	0.66
213_F	230_I	0.510	0.66
231_I	506_A	0.509	0.66
238_G	358_A	0.509	0.66
35_Y	265_I	0.509	0.66
731_I	747_I	0.508	0.65
632_I	751_P	0.508	0.65
414_Q	638_V	0.508	0.65
436_S	620_G	0.508	0.65
415_L	418_K	0.507	0.65
486_V	713_L	0.507	0.65
49_K	66_E	0.507	0.65
99_F	273_I	0.507	0.65
622_V	635_L	0.507	0.65
287_I	366_V	0.506	0.65
376_D	380_L	0.506	0.65
137_A	140_P	0.506	0.65
463_G	497_D	0.506	0.65
144_I	147_K	0.505	0.65
439_A	728_A	0.505	0.65
130_P	343_N	0.505	0.65
492_G	556_N	0.504	0.65
38_V	107_L	0.504	0.65
515_G	659_G	0.504	0.65
407_A	440_F	0.503	0.65
281_R	357_P	0.503	0.65
164_E	168_Y	0.503	0.65
370_S	380_L	0.503	0.65
253_L	257_L	0.503	0.65
181_L	277_H	0.502	0.64
327_P	440_F	0.502	0.64
566_I	569_K	0.502	0.64
663_G	667_S	0.501	0.64
425_G	736_D	0.501	0.64
469_F	507_G	0.501	0.64
370_S	375_I	0.501	0.64
386_I	399_Y	0.501	0.64
58_R	61_N	0.500	0.64

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1rm6A	2	0.9659	100	0.128	Contact Map
1t3qB	2	0.9777	100	0.128	Contact Map
1ffvB	2	0.9724	100	0.135	Contact Map
1n62B	2	0.9751	100	0.139	Contact Map
2w3sB	2	0.9672	100	0.139	Contact Map
3uncA	2	0.9449	100	0.152	Contact Map
3nvzC	2	0.9423	100	0.165	Contact Map
3zyvA	3	0.9396	100	0.166	Contact Map
4usaA	2	0.9396	100	0.171	Contact Map
1dgjA	1	0.937	100	0.173	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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