GREMLIN Database
Q97V57 - Uncharacterized protein
UniProt: Q97V57 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 139 (132)
Sequences: 19939 (16094)
Seq/√Len: 1400.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
33_F83_I3.2151.00
5_L102_I2.8371.00
90_A126_K2.7741.00
3_R33_F2.6471.00
31_R81_E2.5771.00
20_F136_V2.5291.00
3_R31_R2.3831.00
83_I96_F2.3741.00
104_V136_V2.3281.00
33_F102_I1.9711.00
33_F81_E1.9681.00
105_I133_V1.9511.00
107_I127_I1.9481.00
85_V92_S1.9041.00
70_I82_G1.9011.00
125_N129_Q1.8751.00
33_F96_F1.8221.00
97_A105_I1.8221.00
87_G92_S1.7971.00
35_V96_F1.7661.00
6_V21_A1.7051.00
37_V92_S1.6921.00
7_G107_I1.6521.00
7_G93_I1.6351.00
19_D72_K1.5521.00
36_E62_A1.5321.00
24_L28_F1.5081.00
92_S95_Q1.5031.00
70_I74_K1.4521.00
30_A103_D1.4211.00
105_I131_S1.3931.00
63_K67_K1.3911.00
94_L130_E1.3881.00
85_V96_F1.3871.00
15_E72_K1.3701.00
31_R79_N1.3561.00
98_T132_K1.3551.00
6_V18_L1.3391.00
97_A132_K1.2751.00
21_A25_A1.2731.00
126_K130_E1.2721.00
59_E63_K1.2681.00
105_I127_I1.2011.00
89_P123_V1.2001.00
67_K70_I1.1951.00
131_S135_V1.1881.00
35_V85_V1.1701.00
37_V89_P1.1681.00
65_D69_A1.1091.00
20_F24_L1.1071.00
97_A133_V1.1051.00
96_F102_I1.0871.00
115_V119_F1.0841.00
97_A102_I1.0831.00
3_R103_D1.0811.00
67_K82_G1.0731.00
72_K75_S1.0591.00
109_S137_V1.0551.00
26_S76_K1.0301.00
38_I86_E1.0281.00
3_R102_I1.0231.00
94_L97_A1.0201.00
8_Y69_A1.0111.00
4_I104_V0.9991.00
107_I124_S0.9881.00
18_L34_V0.9791.00
23_E27_K0.9791.00
62_A66_V0.9771.00
65_D68_R0.9721.00
62_A65_D0.9641.00
55_T59_E0.9611.00
117_R125_N0.9581.00
21_A106_V0.9481.00
10_G36_E0.9471.00
36_E65_D0.9391.00
67_K71_E0.9351.00
128_V137_V0.9311.00
38_I84_T0.9291.00
34_V80_A0.9251.00
22_I76_K0.9021.00
25_A32_L0.8951.00
28_F103_D0.8941.00
22_I78_V0.8861.00
14_A17_A0.8811.00
11_S14_A0.8791.00
18_L69_A0.8711.00
20_F138_V0.8701.00
20_F23_E0.8701.00
35_V93_I0.8691.00
69_A72_K0.8601.00
112_L116_Q0.8571.00
53_E57_S0.8571.00
62_A84_T0.8561.00
56_K60_E0.8501.00
109_S124_S0.8431.00
8_Y34_V0.8391.00
15_E68_R0.8381.00
124_S137_V0.8351.00
26_S77_G0.8341.00
5_L96_F0.8341.00
20_F134_P0.8321.00
60_E64_K0.8291.00
114_K117_R0.8201.00
8_Y18_L0.8171.00
34_V69_A0.8131.00
22_I73_A0.8081.00
7_G108_G0.8021.00
94_L127_I0.8011.00
66_V82_G0.7981.00
16_R19_D0.7951.00
94_L131_S0.7941.00
21_A32_L0.7931.00
58_L61_R0.7891.00
69_A73_A0.7881.00
15_E19_D0.7851.00
88_D91_N0.7851.00
73_A80_A0.7841.00
18_L22_I0.7691.00
8_Y15_E0.7651.00
115_V118_I0.7621.00
8_Y17_A0.7611.00
5_L35_V0.7541.00
68_R72_K0.7521.00
25_A30_A0.7491.00
5_L105_I0.7491.00
71_E75_S0.7471.00
64_K68_R0.7451.00
61_R65_D0.7431.00
15_E69_A0.7421.00
57_S61_R0.7401.00
106_V136_V0.7401.00
68_R71_E0.7361.00
111_G120_L0.7261.00
90_A123_V0.7181.00
34_V73_A0.7131.00
58_L62_A0.7121.00
101_Q133_V0.7121.00
114_K118_I0.7081.00
93_I127_I0.7051.00
25_A28_F0.6991.00
60_E63_K0.6991.00
11_S111_G0.6991.00
59_E86_E0.6961.00
10_G65_D0.6901.00
24_L27_K0.6871.00
6_V32_L0.6851.00
61_R64_K0.6801.00
57_S60_E0.6721.00
10_G69_A0.6721.00
56_K59_E0.6701.00
38_I62_A0.6691.00
92_S96_F0.6641.00
53_E56_K0.6561.00
107_I137_V0.6561.00
13_N16_R0.6511.00
90_A94_L0.6481.00
71_E74_K0.6451.00
8_Y14_A0.6421.00
54_A57_S0.6291.00
35_V92_S0.6291.00
23_E26_S0.6261.00
24_L106_V0.6251.00
98_T133_V0.6251.00
21_A30_A0.6141.00
120_L124_S0.6121.00
83_I86_E0.6061.00
63_K82_G0.6031.00
91_N95_Q0.6011.00
4_I25_A0.5971.00
22_I26_S0.5961.00
70_I80_A0.5951.00
90_A130_E0.5951.00
4_I106_V0.5921.00
54_A58_L0.5881.00
90_A127_I0.5871.00
50_P53_E0.5821.00
127_I135_V0.5761.00
66_V70_I0.5751.00
49_L52_L0.5741.00
6_V17_A0.5681.00
12_E15_E0.5611.00
110_R124_S0.5591.00
109_S119_F0.5521.00
64_K67_K0.5521.00
106_V138_V0.5491.00
72_K76_K0.5421.00
9_D14_A0.5351.00
55_T86_E0.5291.00
63_K84_T0.5201.00
94_L126_K0.5201.00
24_L136_V0.5171.00
17_A106_V0.5161.00
128_V135_V0.5161.00
42_L45_N0.5151.00
41_T44_Y0.5111.00
16_R20_F0.5071.00
40_L86_E0.5051.00
7_G89_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3s3tA 4 1 99.9 0.127 Contact Map
1mjhA 2 0.9568 99.9 0.135 Contact Map
5ahwA 4 1 99.9 0.135 Contact Map
2gm3A 2 0.8849 99.9 0.14 Contact Map
4wnyA 2 0.8921 99.9 0.14 Contact Map
3idfA 2 0.9784 99.9 0.145 Contact Map
3hgmA 2 0.9928 99.9 0.148 Contact Map
2dumA 2 0.9784 99.9 0.151 Contact Map
3fg9A 3 0.9856 99.9 0.165 Contact Map
3fdxA 2 0.8993 99.9 0.169 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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