Q97V56 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97V56 - Dehydrogenase

UniProt:	Q97V56	Sequences: MEDVKKFKYFTVSPLAFGTWRIGGGYWYSSHDRDNEWVGAIRRAIELGLRVIDTAEMYGNGHAEELVGEAIKEFSREELFIVSKVWPSHADYDNVIKSAKNSSRRLGTYIDLYLLHAPSRVPICKTIRAFEKLVDDGVIRFFGLSNFDVDQIESARECVSKYEIVAIQNHYSLLSRSDERRALAYAEKNGLMYMAYTPLENGILARNEFLANIGKKYNKTATQVALNWYITGKNSLIPIVKASKIPHIEENAGAMGWRLSEEDWRAIDEHFREKSYFLDKFVSSLKSMRPWS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	292 (254)
Sequences:	32247 (20583)
Seq/√Len:	1291.5

ECOLI - YDJG YAJO YDHF GPR TAS YEAE YDBC DKGB DKGA
BACSU - GS69 YCSN YTBE IOLS YCCK YRPG GR YQKF
HALSA - Q9HNN3 Q9HQU7 Q9HPH9 Q9HS02 Q9HSE6 Q9HQT1
SULSO - Q97V56 Q97UG6 Q97ZZ1 Q97UV9 Q97UJ7 Q97U17

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
43_R	249_E	3.199	1.00
100_K	138_V	2.943	1.00
34_D	69_E	2.829	1.00
72_K	107_G	2.812	1.00
217_Y	263_D	2.704	1.00
260_S	263_D	2.531	1.00
38_V	73_E	2.454	1.00
99_A	133_L	2.451	1.00
96_I	132_K	2.403	1.00
96_I	136_D	2.364	1.00
43_R	47_L	2.361	1.00
216_K	266_A	2.162	1.00
131_E	135_D	2.086	1.00
38_V	69_E	2.067	1.00
231_T	264_W	2.026	1.00
109_Y	140_R	2.010	1.00
211_A	215_K	2.000	1.00
216_K	263_D	1.993	1.00
132_K	136_D	1.985	1.00
101_N	105_R	1.983	1.00
185_Y	189_N	1.956	1.00
245_I	249_E	1.934	1.00
261_E	265_R	1.898	1.00
75_S	78_E	1.891	1.00
43_R	245_I	1.868	1.00
186_A	193_Y	1.865	1.00
212_N	266_A	1.840	1.00
92_Y	132_K	1.828	1.00
16_A	51_V	1.819	1.00
47_L	249_E	1.790	1.00
219_K	257_W	1.786	1.00
153_E	157_E	1.715	1.00
81_I	108_T	1.707	1.00
114_L	166_A	1.702	1.00
132_K	135_D	1.698	1.00
44_A	49_L	1.661	1.00
92_Y	96_I	1.659	1.00
153_E	185_Y	1.646	1.00
83_S	110_I	1.636	1.00
47_L	252_A	1.631	1.00
33_R	36_E	1.626	1.00
38_V	42_R	1.619	1.00
65_E	105_R	1.612	1.00
85_V	113_Y	1.601	1.00
83_S	102_S	1.590	1.00
220_T	250_E	1.589	1.00
192_M	237_I	1.584	1.00
42_R	73_E	1.583	1.00
43_R	46_E	1.577	1.00
96_I	100_K	1.574	1.00
227_N	257_W	1.566	1.00
265_R	269_E	1.560	1.00
99_A	113_Y	1.558	1.00
209_F	212_N	1.558	1.00
38_V	70_A	1.553	1.00
85_V	95_V	1.541	1.00
253_G	256_G	1.538	1.00
129_A	132_K	1.534	1.00
82_V	114_L	1.517	1.00
19_T	52_I	1.485	1.00
10_F	141_F	1.465	1.00
97_K	101_N	1.447	1.00
219_K	223_Q	1.440	1.00
45_I	79_L	1.437	1.00
181_R	184_A	1.431	1.00
100_K	104_R	1.424	1.00
114_L	194_M	1.418	1.00
184_A	188_K	1.417	1.00
34_D	38_V	1.417	1.00
36_E	39_G	1.413	1.00
56_E	98_S	1.409	1.00
41_I	70_A	1.370	1.00
156_R	189_N	1.361	1.00
110_I	139_I	1.359	1.00
148_D	151_Q	1.357	1.00
249_E	253_G	1.345	1.00
227_N	231_T	1.326	1.00
10_F	80_F	1.322	1.00
92_Y	128_R	1.314	1.00
219_K	224_V	1.295	1.00
156_R	185_Y	1.292	1.00
42_R	46_E	1.290	1.00
39_G	43_R	1.286	1.00
101_N	104_R	1.284	1.00
266_A	269_E	1.283	1.00
242_A	247_H	1.281	1.00
92_Y	129_A	1.276	1.00
139_I	142_F	1.265	1.00
76_R	108_T	1.264	1.00
133_L	139_I	1.261	1.00
96_I	129_A	1.258	1.00
212_N	216_K	1.257	1.00
135_D	163_E	1.256	1.00
106_L	110_I	1.244	1.00
80_F	112_L	1.235	1.00
242_A	248_I	1.234	1.00
149_V	185_Y	1.229	1.00
220_T	223_Q	1.225	1.00
68_G	107_G	1.219	1.00
52_I	67_V	1.214	1.00
209_F	266_A	1.206	1.00
64_E	102_S	1.200	1.00
124_C	158_C	1.198	1.00
76_R	109_Y	1.191	1.00
69_E	107_G	1.191	1.00
187_E	233_K	1.186	1.00
234_N	268_D	1.177	1.00
35_N	39_G	1.165	1.00
183_L	187_E	1.155	1.00
211_A	221_A	1.147	1.00
91_D	94_N	1.136	1.00
118_P	151_Q	1.133	1.00
93_D	97_K	1.133	1.00
94_N	97_K	1.119	1.00
246_P	249_E	1.117	1.00
51_V	82_V	1.109	1.00
65_E	69_E	1.104	1.00
153_E	188_K	1.104	1.00
229_Y	238_P	1.099	1.00
131_E	134_V	1.097	1.00
51_V	194_M	1.095	1.00
99_A	110_I	1.092	1.00
153_E	189_N	1.086	1.00
212_N	215_K	1.086	1.00
130_F	142_F	1.076	1.00
213_I	224_V	1.071	1.00
19_T	67_V	1.066	1.00
39_G	245_I	1.060	1.00
100_K	136_D	1.059	1.00
42_R	70_A	1.056	1.00
50_R	80_F	1.052	1.00
133_L	138_V	1.048	1.00
187_E	234_N	1.045	1.00
170_H	175_S	1.043	1.00
40_A	248_I	1.043	1.00
8_K	141_F	1.038	1.00
115_L	130_F	1.037	1.00
208_E	212_N	1.037	1.00
223_Q	253_G	1.035	1.00
154_S	158_C	1.023	1.00
125_K	128_R	1.022	1.00
210_L	221_A	1.007	1.00
176_R	207_N	1.007	1.00
13_S	50_R	1.006	1.00
7_F	167_I	1.006	1.00
131_E	163_E	1.002	1.00
149_V	153_E	0.999	1.00
178_D	193_Y	0.998	1.00
208_E	211_A	0.995	1.00
90_A	115_L	0.991	1.00
180_R	184_A	0.979	1.00
64_E	105_R	0.975	1.00
230_I	254_A	0.969	1.00
187_E	235_S	0.965	1.00
184_A	187_E	0.960	1.00
223_Q	250_E	0.957	1.00
14_P	230_I	0.956	1.00
14_P	255_M	0.955	1.00
128_R	132_K	0.954	1.00
69_E	73_E	0.949	1.00
124_C	154_S	0.947	1.00
13_S	49_L	0.946	1.00
194_M	237_I	0.945	1.00
111_D	140_R	0.944	1.00
248_I	252_A	0.933	1.00
71_I	79_L	0.931	1.00
96_I	99_A	0.927	1.00
142_F	164_I	0.921	1.00
133_L	136_D	0.919	1.00
65_E	104_R	0.911	1.00
141_F	165_V	0.910	1.00
246_P	250_E	0.906	1.00
39_G	42_R	0.906	1.00
56_E	94_N	0.906	1.00
97_K	100_K	0.903	1.00
56_E	89_H	0.897	1.00
250_E	253_G	0.896	1.00
176_R	179_E	0.892	1.00
112_L	166_A	0.891	1.00
45_I	75_S	0.889	1.00
185_Y	188_K	0.888	1.00
89_H	94_N	0.884	1.00
129_A	133_L	0.883	1.00
41_I	52_I	0.882	1.00
92_Y	125_K	0.879	1.00
231_T	258_R	0.874	1.00
144_L	164_I	0.874	1.00
265_R	268_D	0.872	1.00
82_V	194_M	0.869	1.00
144_L	152_I	0.855	1.00
244_K	247_H	0.855	1.00
128_R	131_E	0.854	1.00
262_E	266_A	0.853	1.00
96_I	133_L	0.849	1.00
131_E	162_Y	0.846	1.00
82_V	112_L	0.845	1.00
178_D	271_F	0.841	1.00
226_L	254_A	0.832	1.00
262_E	265_R	0.830	1.00
152_I	191_L	0.829	1.00
134_V	165_V	0.827	1.00
131_E	142_F	0.825	1.00
8_K	134_V	0.823	1.00
19_T	63_A	0.822	1.00
216_K	260_S	0.822	1.00
56_E	105_R	0.819	1.00
169_N	193_Y	0.818	1.00
225_A	229_Y	0.813	1.00
154_S	157_E	0.811	1.00
213_I	217_Y	0.809	1.00
103_S	138_V	0.807	1.00
17_F	44_A	0.806	1.00
146_N	196_Y	0.795	1.00
103_S	108_T	0.784	1.00
231_T	261_E	0.782	1.00
56_E	101_N	0.776	1.00
43_R	248_I	0.774	1.00
227_N	254_A	0.767	1.00
209_F	270_H	0.760	1.00
217_Y	260_S	0.754	1.00
183_L	234_N	0.752	1.00
47_L	253_G	0.749	1.00
198_P	240_V	0.748	1.00
83_S	113_Y	0.744	1.00
183_L	193_Y	0.742	1.00
243_S	247_H	0.742	1.00
35_N	38_V	0.741	1.00
195_A	198_P	0.739	1.00
42_R	75_S	0.727	1.00
149_V	182_A	0.723	1.00
49_L	252_A	0.723	1.00
149_V	181_R	0.723	1.00
228_W	268_D	0.721	1.00
54_T	67_V	0.720	1.00
182_A	186_A	0.719	1.00
127_I	142_F	0.718	1.00
127_I	155_A	0.718	1.00
122_P	125_K	0.717	1.00
99_A	138_V	0.712	1.00
117_A	146_N	0.708	1.00
15_L	230_I	0.706	1.00
45_I	52_I	0.705	1.00
144_L	147_F	0.704	1.00
259_L	264_W	0.702	1.00
77_E	109_Y	0.702	1.00
95_V	133_L	0.702	1.00
134_V	164_I	0.701	1.00
102_S	113_Y	0.700	1.00
173_L	225_A	0.699	1.00
222_T	250_E	0.697	1.00
40_A	245_I	0.696	1.00
16_A	240_V	0.696	1.00
90_A	126_T	0.692	1.00
98_S	101_N	0.685	1.00
37_W	66_L	0.684	1.00
114_L	143_G	0.680	1.00
171_Y	179_E	0.675	1.00
215_K	218_N	0.675	1.00
195_A	238_P	0.675	1.00
217_Y	224_V	0.674	1.00
186_A	191_L	0.674	1.00
229_Y	236_L	0.674	1.00
158_C	162_Y	0.668	1.00
95_V	126_T	0.664	1.00
17_F	22_I	0.663	1.00
214_G	224_V	0.658	1.00
198_P	229_Y	0.657	1.00
192_M	236_L	0.656	1.00
50_R	78_E	0.656	1.00
219_K	256_G	0.655	1.00
213_I	263_D	0.652	1.00
247_H	250_E	0.651	1.00
12_V	237_I	0.650	1.00
57_M	86_W	0.650	1.00
219_K	253_G	0.648	1.00
126_T	129_A	0.646	1.00
103_S	109_Y	0.645	1.00
21_R	201_N	0.640	1.00
173_L	267_I	0.640	1.00
8_K	165_V	0.636	1.00
134_V	141_F	0.633	1.00
130_F	134_V	0.632	1.00
210_L	225_A	0.632	1.00
224_V	259_L	0.632	1.00
41_I	45_I	0.630	1.00
16_A	237_I	0.628	1.00
110_I	113_Y	0.627	1.00
207_N	211_A	0.626	1.00
263_D	266_A	0.620	1.00
20_W	197_T	0.620	1.00
47_L	248_I	0.620	1.00
121_V	125_K	0.620	1.00
210_L	267_I	0.619	1.00
46_E	245_I	0.619	1.00
203_I	206_R	0.618	1.00
95_V	129_A	0.616	1.00
153_E	156_R	0.614	1.00
204_L	225_A	0.612	1.00
75_S	79_L	0.612	1.00
213_I	266_A	0.612	1.00
224_V	257_W	0.611	1.00
36_E	245_I	0.611	1.00
45_I	50_R	0.611	1.00
74_F	79_L	0.604	1.00
134_V	139_I	0.601	1.00
219_K	227_N	0.599	1.00
45_I	78_E	0.597	1.00
103_S	110_I	0.597	1.00
87_P	90_A	0.596	1.00
123_I	158_C	0.595	1.00
40_A	242_A	0.593	1.00
96_I	138_V	0.592	1.00
99_A	103_S	0.592	1.00
10_F	140_R	0.591	1.00
224_V	263_D	0.587	1.00
259_L	263_D	0.586	1.00
34_D	66_L	0.586	1.00
203_I	207_N	0.586	1.00
56_E	86_W	0.584	1.00
24_G	66_L	0.583	1.00
22_I	37_W	0.581	1.00
197_T	201_N	0.578	1.00
91_D	126_T	0.578	1.00
85_V	98_S	0.575	1.00
15_L	255_M	0.574	1.00
195_A	235_S	0.574	1.00
151_Q	154_S	0.574	1.00
214_G	217_Y	0.573	1.00
113_Y	139_I	0.565	1.00
206_R	211_A	0.562	1.00
7_F	190_G	0.561	1.00
214_G	221_A	0.560	1.00
41_I	67_V	0.558	1.00
16_A	239_I	0.555	1.00
168_Q	172_S	0.553	1.00
242_A	251_N	0.551	1.00
224_V	267_I	0.551	1.00
144_L	155_A	0.551	1.00
12_V	51_V	0.550	1.00
113_Y	130_F	0.549	1.00
17_F	40_A	0.548	1.00
230_I	238_P	0.545	1.00
210_L	214_G	0.545	1.00
150_D	153_E	0.541	1.00
166_A	194_M	0.538	1.00
223_Q	257_W	0.538	1.00
22_I	40_A	0.537	1.00
134_V	162_Y	0.536	1.00
171_Y	193_Y	0.535	1.00
156_R	191_L	0.534	1.00
92_Y	95_V	0.533	1.00
51_V	80_F	0.533	1.00
123_I	126_T	0.533	1.00
76_R	111_D	0.531	1.00
64_E	83_S	0.528	1.00
173_L	271_F	0.527	1.00
118_P	147_F	0.527	1.00
123_I	154_S	0.526	1.00
156_R	163_E	0.526	1.00
23_G	63_A	0.525	1.00
217_Y	257_W	0.525	1.00
69_E	72_K	0.523	1.00
44_A	52_I	0.522	1.00
127_I	164_I	0.521	1.00
45_I	70_A	0.521	1.00
54_T	63_A	0.520	1.00
115_L	126_T	0.516	1.00
52_I	71_I	0.514	1.00
123_I	151_Q	0.514	1.00
213_I	270_H	0.512	1.00
99_A	129_A	0.512	1.00
245_I	248_I	0.508	1.00
124_C	128_R	0.505	1.00
65_E	107_G	0.504	1.00
226_L	240_V	0.503	1.00
67_V	70_A	0.502	1.00
38_V	66_L	0.501	1.00
227_N	258_R	0.501	1.00
85_V	90_A	0.500	1.00
174_L	203_I	0.500	1.00
264_W	268_D	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3v0sA	1	0.8767	100	0.149	Contact Map
1pyfA	1	0.9212	100	0.15	Contact Map
3lutA	3	0.9281	100	0.155	Contact Map
4xk2A	5	0.9555	100	0.156	Contact Map
1pz1A	1	0.9829	100	0.163	Contact Map
5c7hA	1	0.9418	100	0.165	Contact Map
1lqaA	2	0.9349	100	0.167	Contact Map
3n2tA	1	0.9521	100	0.17	Contact Map
4wghA	1	0.9384	100	0.171	Contact Map
3erpA	6	0.9212	100	0.175	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0095 seconds.