Q97V50 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97V50 - Third ORF in transposon ISC1225

UniProt:	Q97V50	Sequences: MTKDEIVKILIEQVVAMGFRIKLIALDAGFYTVEVIKFISQFNYIIGVPVDDVKIYEEFDGEYVTNSKRHSKDEQVKFRLIVYRREKIKRKRRRLFTSPGLQISIYPRIRSWSNKVRNPIETSYRSVKSFLPFTCSTKFIFRMLIFLLDVLVYSLYTTLKDNVKMRTFKSLISKIIENISEIEIYLNKLEETLTNTIGLFLRR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	203 (168)
Sequences:	149 (98)
Seq/√Len:	7.6

HALSA - Q9HHP9 O51989 O51959
SULSO - Q97V50 Q97UV3 Q97Y40 Q97UW1 Q97TV3 Q97Y64 Q97YD0 Q97XT0 Q97XW2 Q97WW6 Q7LXX4 Q97YS0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
26_L	123_S	3.686	0.95
144_L	148_L	3.291	0.91
101_L	118_N	2.923	0.84
28_A	47_G	2.900	0.84
10_L	153_Y	2.576	0.76
14_V	24_I	2.563	0.75
21_I	45_I	2.485	0.73
130_F	153_Y	2.378	0.69
14_V	44_Y	2.320	0.67
122_T	125_R	2.119	0.60
31_Y	155_L	2.071	0.58
133_F	154_S	2.041	0.57
101_L	136_S	1.952	0.53
101_L	153_Y	1.927	0.52
39_I	42_F	1.798	0.47
14_V	19_F	1.761	0.46
6_I	10_L	1.737	0.45
24_I	101_L	1.708	0.44
175_I	178_N	1.690	0.43
26_L	31_Y	1.685	0.43
114_N	154_S	1.648	0.41
122_T	158_T	1.638	0.41
8_K	68_K	1.622	0.40
128_K	136_S	1.620	0.40
31_Y	48_V	1.604	0.40
56_Y	143_M	1.599	0.40
11_I	30_F	1.586	0.39
19_F	64_V	1.551	0.38
119_P	149_D	1.547	0.38
46_I	105_I	1.536	0.37
114_N	119_P	1.534	0.37
80_L	147_L	1.523	0.37
21_I	124_Y	1.507	0.36
21_I	52_D	1.503	0.36
21_I	85_R	1.482	0.35
160_K	164_K	1.479	0.35
101_L	144_L	1.478	0.35
128_K	153_Y	1.458	0.34
175_I	179_I	1.454	0.34
31_Y	49_P	1.425	0.33
80_L	92_R	1.408	0.32
144_L	152_V	1.406	0.32
49_P	131_L	1.404	0.32
146_F	153_Y	1.382	0.32
45_I	55_I	1.374	0.31
117_R	121_E	1.373	0.31
101_L	146_F	1.359	0.31
27_D	121_E	1.353	0.31
173_S	177_E	1.334	0.30
121_E	142_R	1.325	0.30
141_F	155_L	1.323	0.30
18_G	48_V	1.314	0.29
29_G	49_P	1.307	0.29
46_I	103_I	1.300	0.29
46_I	133_F	1.299	0.29
27_D	117_R	1.298	0.29
23_L	129_S	1.294	0.29
117_R	142_R	1.271	0.28
10_L	124_Y	1.264	0.28
131_L	143_M	1.261	0.28
35_V	120_I	1.255	0.27
27_D	142_R	1.253	0.27
127_V	161_D	1.243	0.27
102_Q	130_F	1.234	0.27
38_F	41_Q	1.234	0.27
152_V	163_V	1.226	0.26
23_L	42_F	1.222	0.26
132_P	137_T	1.219	0.26
39_I	143_M	1.193	0.25
45_I	70_H	1.153	0.24
173_S	178_N	1.151	0.24
23_L	103_I	1.150	0.24
65_T	108_R	1.148	0.24
122_T	155_L	1.147	0.24
90_R	94_R	1.134	0.24
35_V	122_T	1.134	0.24
48_V	119_P	1.128	0.24
131_L	135_C	1.126	0.23
73_D	96_F	1.119	0.23
9_I	94_R	1.112	0.23
35_V	134_T	1.111	0.23
99_P	118_N	1.107	0.23
80_L	98_S	1.090	0.22
30_F	124_Y	1.069	0.22
60_D	122_T	1.063	0.22
10_L	44_Y	1.060	0.22
112_W	125_R	1.060	0.22
160_K	178_N	1.054	0.21
52_D	57_E	1.051	0.21
58_E	61_G	1.044	0.21
99_P	136_S	1.040	0.21
99_P	146_F	1.038	0.21
8_K	91_K	1.032	0.21
101_L	148_L	1.029	0.21
102_Q	146_F	1.007	0.20
39_I	63_Y	1.000	0.20
36_I	100_G	0.994	0.20
19_F	48_V	0.984	0.20
102_Q	118_N	0.972	0.19
113_S	120_I	0.971	0.19
102_Q	136_S	0.971	0.19
39_I	46_I	0.969	0.19
64_V	82_V	0.962	0.19
135_C	147_L	0.946	0.19
62_E	72_K	0.942	0.19
26_L	39_I	0.936	0.18
128_K	148_L	0.920	0.18
35_V	113_S	0.919	0.18
36_I	122_T	0.905	0.18
35_V	124_Y	0.903	0.18
36_I	39_I	0.903	0.18
31_Y	122_T	0.902	0.18
63_Y	68_K	0.898	0.18
42_F	164_K	0.896	0.18
57_E	61_G	0.878	0.17
41_Q	114_N	0.878	0.17
34_E	122_T	0.877	0.17
56_Y	166_R	0.876	0.17
124_Y	134_T	0.863	0.17
138_K	151_L	0.856	0.17
44_Y	102_Q	0.855	0.17
18_G	144_L	0.854	0.17
53_V	56_Y	0.845	0.16
83_Y	124_Y	0.842	0.16
176_I	179_I	0.837	0.16
118_N	144_L	0.835	0.16
19_F	24_I	0.834	0.16
40_S	70_H	0.823	0.16
22_K	131_L	0.811	0.16
37_K	114_N	0.808	0.16
12_E	35_V	0.806	0.16
118_N	130_F	0.805	0.16
118_N	136_S	0.804	0.16
72_K	78_F	0.796	0.15
74_E	141_F	0.791	0.15
105_I	145_I	0.789	0.15
47_G	113_S	0.785	0.15
44_Y	126_S	0.783	0.15
172_I	179_I	0.782	0.15
52_D	154_S	0.771	0.15
54_K	81_I	0.763	0.15
107_P	157_T	0.761	0.15
127_V	149_D	0.759	0.15
101_L	130_F	0.759	0.15
68_K	71_S	0.757	0.15
148_L	162_N	0.757	0.15
127_V	146_F	0.754	0.14
48_V	109_I	0.750	0.14
95_L	163_V	0.749	0.14
57_E	74_E	0.747	0.14
28_A	150_V	0.746	0.14
159_L	162_N	0.739	0.14
45_I	83_Y	0.734	0.14
83_Y	154_S	0.732	0.14
25_A	132_P	0.730	0.14
39_I	75_Q	0.726	0.14
139_F	154_S	0.725	0.14
21_I	79_R	0.725	0.14
8_K	145_I	0.724	0.14
68_K	72_K	0.722	0.14
9_I	47_G	0.710	0.14
57_E	60_D	0.709	0.14
148_L	159_L	0.706	0.14
162_N	178_N	0.704	0.14
20_R	74_E	0.703	0.14
156_Y	160_K	0.702	0.13
97_T	159_L	0.701	0.13
25_A	145_I	0.695	0.13
113_S	121_E	0.693	0.13
12_E	24_I	0.692	0.13
143_M	150_V	0.677	0.13
72_K	138_K	0.675	0.13
29_G	112_W	0.675	0.13
146_F	162_N	0.673	0.13
59_F	138_K	0.673	0.13
136_S	148_L	0.672	0.13
157_T	160_K	0.671	0.13
48_V	66_N	0.665	0.13
7_V	14_V	0.663	0.13
131_L	150_V	0.661	0.13
24_I	136_S	0.660	0.13
23_L	164_K	0.660	0.13
67_S	78_F	0.657	0.13
29_G	111_S	0.655	0.13
43_N	97_T	0.648	0.13
12_E	132_P	0.643	0.12
99_P	102_Q	0.641	0.12
174_K	179_I	0.638	0.12
6_I	143_M	0.638	0.12
48_V	124_Y	0.636	0.12
120_I	156_Y	0.634	0.12
5_E	41_Q	0.633	0.12
77_K	105_I	0.631	0.12
36_I	46_I	0.630	0.12
45_I	110_R	0.629	0.12
81_I	106_Y	0.629	0.12
64_V	134_T	0.623	0.12
32_T	122_T	0.622	0.12
144_L	149_D	0.619	0.12
60_D	129_S	0.619	0.12
33_V	75_Q	0.615	0.12
113_S	117_R	0.606	0.12
28_A	61_G	0.602	0.12
11_I	51_D	0.601	0.12
44_Y	136_S	0.595	0.12
30_F	121_E	0.595	0.12
27_D	113_S	0.591	0.12
134_T	143_M	0.584	0.11
99_P	160_K	0.582	0.11
82_V	140_I	0.579	0.11
24_I	93_R	0.578	0.11
29_G	149_D	0.578	0.11
13_Q	137_T	0.577	0.11
42_F	147_L	0.577	0.11
12_E	38_F	0.576	0.11
46_I	100_G	0.575	0.11
39_I	145_I	0.569	0.11
75_Q	80_L	0.569	0.11
83_Y	129_S	0.567	0.11
47_G	134_T	0.566	0.11
22_K	111_S	0.566	0.11
10_L	40_S	0.563	0.11
12_E	179_I	0.561	0.11
20_R	43_N	0.560	0.11
57_E	152_V	0.559	0.11
113_S	142_R	0.559	0.11
65_T	162_N	0.558	0.11
172_I	175_I	0.556	0.11
102_Q	110_R	0.555	0.11
81_I	134_T	0.555	0.11
49_P	149_D	0.554	0.11
45_I	152_V	0.539	0.11
149_D	166_R	0.539	0.11
21_I	120_I	0.535	0.11
128_K	132_P	0.531	0.11
40_S	166_R	0.529	0.11
35_V	77_K	0.529	0.11
36_I	139_F	0.528	0.11
55_I	111_S	0.528	0.11
43_N	60_D	0.527	0.11
131_L	149_D	0.526	0.11
101_L	128_K	0.524	0.10
136_S	153_Y	0.522	0.10
64_V	140_I	0.520	0.10
15_V	35_V	0.520	0.10
20_R	92_R	0.520	0.10
15_V	149_D	0.518	0.10
34_E	97_T	0.515	0.10
22_K	118_N	0.514	0.10
30_F	117_R	0.508	0.10
115_K	122_T	0.506	0.10
30_F	134_T	0.500	0.10

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1musA	2	0.9212	98.7	0.836	Contact Map
1f6yA	2	0.5172	14.2	0.958	Contact Map
2yciX	2	0.5172	11.7	0.959	Contact Map
4ggjA	2	0.5222	9.4	0.961	Contact Map
4gelA	2	0.5862	7.4	0.963	Contact Map
4o1eA	2	0.5468	6.4	0.964	Contact Map
3fp5A	1	0.1773	3.7	0.968	Contact Map
1iukA	1	0.2857	3.4	0.968	Contact Map
2e9fA	4	0.3251	3.2	0.969	Contact Map
3hh1A	2	0.2315	3	0.969	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.