GREMLIN Database
Q97V11 - Uncharacterized protein
UniProt: Q97V11 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 209 (177)
Sequences: 4143 (2461)
Seq/√Len: 184.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
84_S153_Y3.6661.00
75_T78_D3.3171.00
110_P113_Y3.1961.00
86_E107_K3.1911.00
69_E119_K3.0651.00
65_D188_H3.0401.00
69_E121_K2.8791.00
65_D186_R2.8771.00
82_M117_M2.6611.00
129_G187_L2.5351.00
130_Y186_R2.4841.00
61_V73_K2.4151.00
107_K154_M2.3501.00
63_T73_K2.2991.00
72_L118_V2.1571.00
151_I168_V2.1381.00
116_D145_K2.1101.00
113_Y116_D2.0671.00
86_E105_L2.0551.00
115_I189_F2.0421.00
91_I177_G2.0291.00
67_E191_S1.9591.00
56_M59_N1.9511.00
128_V190_T1.9401.00
127_V189_F1.8461.00
88_K105_L1.8421.00
139_L172_V1.8351.00
114_V151_I1.8191.00
105_L157_D1.8091.00
104_V155_A1.8061.00
67_E121_K1.7901.00
152_A171_V1.7881.00
112_S116_D1.7781.00
84_S107_K1.7311.00
123_N191_S1.7281.00
132_A185_V1.6821.00
128_V188_H1.6111.00
70_N119_K1.5761.00
85_I110_P1.5601.00
111_L144_A1.5491.00
72_L117_M1.4991.00
130_Y188_H1.4981.00
63_T186_R1.4741.00
129_G184_L1.4681.00
80_L153_Y1.4641.00
124_V189_F1.4641.00
43_W104_V1.4561.00
90_T103_N1.4141.00
151_I184_L1.4111.00
109_I114_V1.4011.00
68_I71_P1.3971.00
202_G205_D1.3951.00
76_Y80_L1.3841.00
67_E123_N1.3821.00
81_N117_M1.3811.00
154_M159_P1.3681.00
74_L117_M1.3291.00
129_G170_L1.3101.00
58_N77_Q1.3061.00
84_S154_M1.3031.00
149_V172_V1.3031.00
127_V144_A1.2961.00
78_D81_N1.2261.00
172_V180_Y1.2221.00
112_S147_P1.2191.00
195_L200_S1.1981.00
146_E149_V1.1831.00
91_I180_Y1.1821.00
37_L88_K1.1551.00
111_L187_L1.1521.00
60_Y76_Y1.1261.00
82_M109_I1.1181.00
79_L168_V1.0891.00
196_G199_E1.0871.00
143_K175_W1.0681.00
37_L155_A1.0661.00
33_A37_L1.0271.00
66_G71_P1.0251.00
43_W102_A1.0231.00
87_V150_L1.0161.00
115_I120_P1.0050.99
85_I150_L1.0050.99
57_L76_Y1.0010.99
80_L154_M1.0000.99
141_I189_F0.9970.99
40_F161_P0.9960.99
137_A181_V0.9960.99
143_K174_G0.9930.99
137_A178_Y0.9910.99
107_K153_Y0.9880.99
43_W155_A0.9840.99
83_P110_P0.9800.99
125_I191_S0.9670.99
195_L199_E0.9620.99
85_I113_Y0.9600.99
105_L156_D0.9570.99
83_P113_Y0.9530.99
68_I189_F0.9490.99
64_V68_I0.9440.99
77_Q80_L0.9380.99
67_E124_V0.9370.99
137_A179_T0.9100.99
120_P189_F0.8990.99
109_I153_Y0.8930.99
47_Q52_V0.8900.99
55_I132_A0.8850.99
64_V72_L0.8830.99
40_F104_V0.8780.99
60_Y168_V0.8770.99
143_K206_Y0.8610.98
58_N76_Y0.8550.98
62_L168_V0.8510.98
188_H194_I0.8430.98
111_L170_L0.8430.98
54_D162_Q0.8400.98
120_P141_I0.8280.98
155_A164_H0.8240.98
45_V163_V0.8200.98
74_L118_V0.8200.98
91_I104_V0.8180.98
131_G181_V0.8160.98
170_L181_V0.8150.98
34_Q158_K0.8120.98
52_V163_V0.8060.97
129_G181_V0.8050.97
46_V49_S0.7990.97
32_H37_L0.7990.97
84_S109_I0.7920.97
43_W183_W0.7910.97
32_H36_G0.7900.97
88_K103_N0.7850.97
104_V156_D0.7840.97
94_V178_Y0.7810.97
33_A36_G0.7800.97
171_V180_Y0.7690.97
140_P143_K0.7610.96
77_Q81_N0.7590.96
80_L159_P0.7550.96
155_A161_P0.7540.96
151_I170_L0.7510.96
153_Y159_P0.7500.96
153_Y168_V0.7490.96
170_L184_L0.7430.96
68_I118_V0.7340.96
128_V199_E0.7240.95
109_I113_Y0.7190.95
63_T71_P0.7190.95
79_L109_I0.7170.95
68_I124_V0.7130.95
47_Q183_W0.7110.95
68_I72_L0.7080.95
96_D99_F0.7050.95
32_H35_N0.6970.94
127_V187_L0.6800.93
113_Y117_M0.6790.93
110_P150_L0.6780.93
161_P164_H0.6780.93
82_M113_Y0.6740.93
152_A170_L0.6700.93
201_L204_P0.6630.93
57_L166_Y0.6610.92
136_T200_S0.6600.92
92_Q137_A0.6540.92
178_Y199_E0.6540.92
72_L78_D0.6500.92
126_K138_D0.6450.92
197_Y202_G0.6450.92
143_K146_E0.6440.91
126_K194_I0.6430.91
128_V194_I0.6420.91
146_E174_G0.6390.91
69_E72_L0.6370.91
65_D71_P0.6350.91
74_L78_D0.6340.91
64_V74_L0.6340.91
137_A199_E0.6290.90
102_A155_A0.6290.90
40_F158_K0.6250.90
54_D58_N0.6240.90
52_V162_Q0.6210.90
94_V176_W0.6190.90
107_K110_P0.6190.90
129_G135_Y0.6150.90
130_Y136_T0.6130.89
176_W179_T0.6090.89
109_I151_I0.6080.89
115_I145_K0.6080.89
152_A168_V0.6080.89
190_T194_I0.6070.89
31_Q34_Q0.6070.89
95_S178_Y0.6030.89
79_L153_Y0.6010.88
91_I171_V0.5980.88
40_F155_A0.5970.88
143_K149_V0.5960.88
150_L171_V0.5950.88
128_V136_T0.5950.88
29_E33_A0.5920.88
111_L149_V0.5910.88
126_K193_N0.5910.88
66_G124_V0.5900.88
175_W179_T0.5900.88
104_V171_V0.5890.87
111_L115_I0.5850.87
38_T161_P0.5830.87
90_T95_S0.5810.87
65_D68_I0.5810.87
102_A177_G0.5810.87
196_G200_S0.5780.86
184_L187_L0.5770.86
62_L74_L0.5710.86
111_L189_F0.5700.86
67_E71_P0.5660.85
46_V95_S0.5660.85
144_A149_V0.5650.85
74_L82_M0.5580.84
128_V195_L0.5570.84
40_F43_W0.5540.84
94_V198_W0.5530.84
148_N174_G0.5520.84
135_Y178_Y0.5510.84
65_D130_Y0.5510.84
115_I118_V0.5420.83
90_T100_L0.5410.83
62_L151_I0.5410.83
109_I168_V0.5410.83
27_I32_H0.5400.83
197_Y201_L0.5380.82
170_L187_L0.5370.82
69_E122_S0.5360.82
158_K161_P0.5330.82
55_I133_D0.5310.81
193_N199_E0.5310.81
62_L79_L0.5300.81
102_A106_W0.5290.81
138_D178_Y0.5290.81
100_L179_T0.5280.81
29_E32_H0.5280.81
67_E190_T0.5280.81
95_S175_W0.5280.81
74_L114_V0.5260.81
92_Q95_S0.5240.81
152_A160_L0.5240.81
95_S99_F0.5190.80
69_E127_V0.5180.80
47_Q53_P0.5170.80
61_V75_T0.5150.79
62_L186_R0.5150.79
89_D171_V0.5130.79
142_E145_K0.5120.79
31_Q37_L0.5110.79
43_W106_W0.5100.79
86_E157_D0.5090.79
114_V168_V0.5080.79
27_I31_Q0.5080.79
138_D199_E0.5080.79
94_V101_R0.5070.78
49_S180_Y0.5060.78
99_F179_T0.5060.78
192_K195_L0.5050.78
43_W198_W0.5050.78
47_Q51_I0.5040.78
139_L175_W0.5020.78
56_M134_G0.5000.77
125_I141_I0.5000.77
117_M120_P0.5000.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2a9dA 2 0.9856 100 0.187 Contact Map
2blfA 1 1 100 0.19 Contact Map
1ogpA 4 0.9856 100 0.19 Contact Map
1soxA 2 0.9952 100 0.19 Contact Map
2biiA 2 0.8947 100 0.216 Contact Map
2bihA 2 0.9713 100 0.216 Contact Map
4pw3A 2 0.9426 100 0.225 Contact Map
2xtsA 2 0.9665 100 0.234 Contact Map
1xdyA 3 0.9187 100 0.249 Contact Map
2pq4B 1 0.1675 36.9 0.951 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0078 seconds.