Q97UZ1 - SULSO - GREMLIN Contacts

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Q97UZ1 - Sugar-binding periplasmic protein

UniProt:	Q97UZ1	Sequences: MKRKYPYSLAKGLTSTQIAVIVAVIVIVIIIGVVAGFVLTKGPSTTAVTTTVTSTFTTTTTIPSTTTSTPSNTVVFYTWWGGGDGGEALSQIIPAVKQYAGLQMQTYSIPGAGGTNAKYAILALIQAGKPPAAFQVHYGPEMISYVEAAPNGIHTFVNMTPYLIQWGLLNNAVYAVLQAGAYNGTLLSVPINVHRGAVLYVNTQLLREYNLPFPYNFSTLVYDTVQLANHGVSPWIIPGGDGGWDQFNVWEDIFLYLAGPQLYNELIYGTLNFSNPTVQKLINETNYWFLNFTSYNYPGWQSMSWEQAFALIAQGKVAFQANGNWVTNYASYINVTVYPPLPQYISNSSVSVVETPFPGTQHYYALVIDTIGIPVGPQEQQALQLAHFWSSYQGQEVWTKYKAVTYYKNGTDWYAQPAQWYDYQQLINTSEQNFVYQLSDGGVFDDVFAQIDSGLLTLQQVGKVGLSAWNSTLVSSMQQEQNEWLAAAKLGLGYLGFPGHPFAGYYPPWVTNPSAYGLTNNTQKTSNSVMLFLLPFLALPLAIASIDNKYYLLK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	554 (429)
Sequences:	8449 (7308)
Seq/√Len:	352.8

ECOLI - UGPB YCJN MALE
BACSU - YURO YESO YTCQ LIPO CYCB ARAN MSME MDXE
HALSA - Q9HHQ8
SULSO - Q97UZ1 Q97UF5 Q97YY1 Q97ZC3 Q97VC2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
286_N	290_L	4.258	1.00
73_T	105_Q	4.249	1.00
461_V	464_V	4.239	1.00
73_T	103_Q	3.721	1.00
203_T	207_R	3.654	1.00
225_V	291_N	3.337	1.00
221_V	287_Y	3.325	1.00
287_Y	291_N	3.274	1.00
157_V	379_E	3.265	1.00
279_Q	463_K	3.226	1.00
158_N	185_T	3.084	1.00
225_V	229_N	3.083	1.00
471_S	475_S	2.965	1.00
75_V	105_Q	2.955	1.00
160_T	185_T	2.927	1.00
204_Q	351_S	2.871	1.00
283_N	287_Y	2.825	1.00
29_I	32_G	2.770	1.00
474_V	478_Q	2.755	1.00
203_T	353_V	2.632	1.00
467_S	471_S	2.632	1.00
216_N	219_T	2.595	1.00
222_Y	226_Q	2.565	1.00
90_S	94_P	2.545	1.00
276_P	280_K	2.480	1.00
463_K	467_S	2.468	1.00
91_Q	94_P	2.375	1.00
71_S	103_Q	2.332	1.00
174_Y	178_Q	2.332	1.00
219_T	222_Y	2.328	1.00
95_A	98_Q	2.319	1.00
222_Y	225_V	2.273	1.00
97_K	103_Q	2.258	1.00
212_P	215_Y	2.257	1.00
206_L	319_F	2.249	1.00
468_A	472_T	2.212	1.00
102_L	381_Q	2.167	1.00
280_K	283_N	2.162	1.00
291_N	295_Y	2.144	1.00
378_Q	381_Q	2.141	1.00
424_Q	428_N	2.139	1.00
384_Q	387_H	2.117	1.00
99_Y	384_Q	2.107	1.00
96_V	384_Q	2.087	1.00
226_Q	230_H	2.065	1.00
204_Q	208_E	2.034	1.00
30_I	33_V	2.025	1.00
283_N	463_K	1.996	1.00
201_V	353_V	1.995	1.00
116_N	119_Y	1.993	1.00
477_M	480_E	1.990	1.00
265_E	268_Y	1.977	1.00
221_V	288_W	1.973	1.00
304_S	307_Q	1.967	1.00
283_N	462_G	1.958	1.00
158_N	161_P	1.885	1.00
274_S	467_S	1.880	1.00
75_V	107_Y	1.878	1.00
471_S	474_V	1.853	1.00
470_N	474_V	1.853	1.00
211_L	223_D	1.842	1.00
156_F	372_G	1.834	1.00
464_V	468_A	1.803	1.00
468_A	471_S	1.800	1.00
77_Y	124_L	1.748	1.00
279_Q	283_N	1.745	1.00
221_V	225_V	1.721	1.00
472_T	475_S	1.712	1.00
391_S	394_G	1.709	1.00
284_E	288_W	1.704	1.00
181_A	186_L	1.696	1.00
71_S	101_G	1.687	1.00
464_V	467_S	1.642	1.00
454_G	460_Q	1.641	1.00
221_V	291_N	1.631	1.00
162_Y	383_L	1.613	1.00
284_E	287_Y	1.599	1.00
188_S	370_T	1.596	1.00
218_S	222_Y	1.570	1.00
218_S	221_V	1.569	1.00
72_N	381_Q	1.567	1.00
203_T	351_S	1.548	1.00
467_S	470_N	1.540	1.00
132_A	378_Q	1.539	1.00
454_G	459_Q	1.538	1.00
460_Q	468_A	1.538	1.00
225_V	295_Y	1.524	1.00
87_E	91_Q	1.523	1.00
178_Q	181_A	1.517	1.00
447_V	472_T	1.514	1.00
396_E	400_K	1.509	1.00
120_A	124_L	1.508	1.00
211_L	226_Q	1.499	1.00
455_L	465_G	1.497	1.00
224_T	319_F	1.496	1.00
157_V	375_V	1.478	1.00
205_L	227_L	1.477	1.00
380_Q	384_Q	1.473	1.00
359_G	362_H	1.441	1.00
425_Q	428_N	1.440	1.00
264_N	268_Y	1.435	1.00
279_Q	462_G	1.432	1.00
20_V	26_V	1.431	1.00
134_F	374_P	1.429	1.00
227_L	318_A	1.422	1.00
381_Q	384_Q	1.414	1.00
205_L	318_A	1.401	1.00
86_G	90_S	1.397	1.00
74_V	382_A	1.392	1.00
161_P	164_I	1.392	1.00
171_N	410_G	1.391	1.00
209_Y	227_L	1.390	1.00
205_L	209_Y	1.386	1.00
421_Y	424_Q	1.386	1.00
392_Y	396_E	1.386	1.00
214_P	219_T	1.382	1.00
72_N	378_Q	1.381	1.00
215_Y	219_T	1.378	1.00
418_A	421_Y	1.372	1.00
228_A	295_Y	1.358	1.00
94_P	97_K	1.352	1.00
446_D	450_Q	1.352	1.00
274_S	470_N	1.343	1.00
221_V	284_E	1.331	1.00
164_I	169_L	1.325	1.00
421_Y	425_Q	1.297	1.00
418_A	422_D	1.292	1.00
23_A	26_V	1.287	1.00
425_Q	429_T	1.287	1.00
95_A	99_Y	1.286	1.00
465_G	468_A	1.278	1.00
460_Q	465_G	1.269	1.00
149_A	375_V	1.269	1.00
466_L	470_N	1.257	1.00
224_T	295_Y	1.241	1.00
373_I	383_L	1.232	1.00
87_E	90_S	1.231	1.00
223_D	226_Q	1.227	1.00
91_Q	95_A	1.227	1.00
125_I	130_P	1.218	1.00
451_I	454_G	1.215	1.00
201_V	355_T	1.213	1.00
228_A	234_P	1.197	1.00
455_L	462_G	1.197	1.00
28_V	31_I	1.194	1.00
286_N	455_L	1.192	1.00
199_L	319_F	1.191	1.00
97_K	100_A	1.191	1.00
264_N	270_T	1.190	1.00
93_I	97_K	1.183	1.00
307_Q	310_A	1.183	1.00
199_L	355_T	1.181	1.00
167_G	387_H	1.179	1.00
206_L	223_D	1.178	1.00
450_Q	454_G	1.169	1.00
451_I	468_A	1.159	1.00
312_I	352_V	1.153	1.00
232_V	235_W	1.143	1.00
136_V	372_G	1.141	1.00
220_L	319_F	1.139	1.00
223_D	227_L	1.128	1.00
220_L	224_T	1.127	1.00
211_L	227_L	1.120	1.00
450_Q	472_T	1.115	1.00
146_V	182_Y	1.113	1.00
146_V	187_L	1.113	1.00
33_V	36_G	1.106	1.00
29_I	33_V	1.106	1.00
228_A	294_S	1.106	1.00
74_V	385_L	1.104	1.00
373_I	386_A	1.101	1.00
445_D	449_A	1.095	1.00
422_D	425_Q	1.092	1.00
451_I	469_W	1.088	1.00
166_W	387_H	1.087	1.00
133_A	386_A	1.087	1.00
212_P	219_T	1.086	1.00
209_Y	230_H	1.085	1.00
133_A	382_A	1.082	1.00
236_I	317_V	1.081	1.00
311_L	316_K	1.079	1.00
121_I	134_F	1.077	1.00
92_I	95_A	1.077	1.00
226_Q	229_N	1.076	1.00
388_F	394_G	1.070	1.00
180_G	186_L	1.070	1.00
93_I	385_L	1.070	1.00
88_A	91_Q	1.066	1.00
466_L	469_W	1.065	1.00
31_I	34_V	1.060	1.00
261_Q	264_N	1.059	1.00
231_G	235_W	1.057	1.00
417_P	421_Y	1.051	1.00
287_Y	290_L	1.048	1.00
120_A	123_A	1.034	1.00
76_F	371_I	1.033	1.00
28_V	32_G	1.032	1.00
180_G	370_T	1.030	1.00
288_W	295_Y	1.023	1.00
279_Q	467_S	1.010	1.00
134_F	372_G	1.010	1.00
30_I	34_V	1.007	1.00
160_T	164_I	1.005	1.00
95_A	388_F	0.999	1.00
221_V	295_Y	0.994	1.00
417_P	420_W	0.994	1.00
198_V	354_E	0.992	1.00
175_A	178_Q	0.991	1.00
277_T	280_K	0.990	1.00
17_Q	20_V	0.989	1.00
110_P	116_N	0.986	1.00
167_G	170_N	0.984	1.00
286_N	462_G	0.984	1.00
259_G	262_L	0.983	1.00
201_V	206_L	0.982	1.00
27_I	33_V	0.980	1.00
443_V	446_D	0.980	1.00
102_L	384_Q	0.976	1.00
385_L	389_W	0.972	1.00
125_I	150_P	0.964	1.00
65_T	68_S	0.963	1.00
209_Y	226_Q	0.960	1.00
163_L	186_L	0.958	1.00
233_S	236_I	0.956	1.00
96_V	388_F	0.955	1.00
375_V	379_E	0.953	1.00
231_G	237_I	0.950	1.00
447_V	450_Q	0.947	1.00
40_T	43_P	0.946	1.00
394_G	397_V	0.945	1.00
97_K	101_G	0.943	1.00
28_V	33_V	0.942	1.00
157_V	374_P	0.941	1.00
376_G	379_E	0.937	1.00
18_I	21_I	0.937	1.00
207_R	351_S	0.935	1.00
205_L	208_E	0.934	1.00
71_S	100_A	0.933	1.00
294_S	298_P	0.927	1.00
451_I	460_Q	0.927	1.00
160_T	186_L	0.927	1.00
177_L	186_L	0.926	1.00
231_G	234_P	0.923	1.00
20_V	23_A	0.922	1.00
261_Q	265_E	0.922	1.00
265_E	270_T	0.922	1.00
447_V	451_I	0.921	1.00
276_P	279_Q	0.921	1.00
22_V	26_V	0.919	1.00
408_K	411_T	0.919	1.00
96_V	385_L	0.915	1.00
234_P	237_I	0.912	1.00
78_T	106_T	0.911	1.00
264_N	269_G	0.910	1.00
36_G	39_L	0.905	1.00
77_Y	109_I	0.900	1.00
472_T	476_S	0.899	1.00
348_S	352_V	0.898	1.00
279_Q	466_L	0.897	1.00
162_Y	380_Q	0.895	1.00
27_I	31_I	0.894	1.00
225_V	228_A	0.894	1.00
64_S	67_T	0.892	1.00
207_R	213_F	0.887	1.00
436_Y	441_G	0.886	1.00
224_T	228_A	0.886	1.00
20_V	27_I	0.883	1.00
403_A	407_Y	0.883	1.00
76_F	133_A	0.880	1.00
202_N	205_L	0.877	1.00
280_K	284_E	0.875	1.00
157_V	162_Y	0.874	1.00
96_V	102_L	0.870	1.00
74_V	378_Q	0.869	1.00
259_G	264_N	0.868	1.00
204_Q	207_R	0.867	1.00
61_T	64_S	0.866	1.00
72_N	101_G	0.866	1.00
310_A	314_Q	0.866	1.00
447_V	476_S	0.864	1.00
443_V	476_S	0.861	1.00
297_Y	311_L	0.857	1.00
397_V	401_Y	0.855	1.00
160_T	181_A	0.854	1.00
385_L	388_F	0.853	1.00
217_F	284_E	0.851	1.00
146_V	156_F	0.850	1.00
25_I	29_I	0.849	1.00
58_T	61_T	0.849	1.00
414_Y	418_A	0.849	1.00
25_I	28_V	0.848	1.00
25_I	31_I	0.844	1.00
420_W	424_Q	0.841	1.00
232_V	236_I	0.840	1.00
22_V	25_I	0.837	1.00
41_K	44_S	0.834	1.00
208_E	230_H	0.830	1.00
95_A	397_V	0.827	1.00
446_D	449_A	0.817	1.00
133_A	385_L	0.816	1.00
205_L	232_V	0.814	1.00
162_Y	166_W	0.814	1.00
451_I	472_T	0.813	1.00
62_I	65_T	0.810	1.00
118_K	141_E	0.810	1.00
397_V	400_K	0.809	1.00
379_E	383_L	0.809	1.00
130_P	374_P	0.809	1.00
444_F	473_L	0.808	1.00
423_Y	427_I	0.808	1.00
119_Y	123_A	0.801	1.00
474_V	479_Q	0.800	1.00
27_I	30_I	0.798	1.00
69_T	101_G	0.797	1.00
162_Y	379_E	0.793	1.00
55_T	58_T	0.790	1.00
104_M	385_L	0.787	1.00
249_V	252_D	0.787	1.00
158_N	187_L	0.787	1.00
382_A	386_A	0.786	1.00
202_N	350_V	0.783	1.00
161_P	185_T	0.776	1.00
329_Y	332_Y	0.775	1.00
18_I	26_V	0.773	1.00
54_S	57_T	0.773	1.00
347_N	350_V	0.772	1.00
393_Q	396_E	0.771	1.00
188_S	372_G	0.770	1.00
383_L	387_H	0.767	1.00
26_V	30_I	0.766	1.00
96_V	99_Y	0.762	1.00
460_Q	464_V	0.761	1.00
134_F	156_F	0.758	1.00
379_E	382_A	0.758	1.00
60_T	63_P	0.757	1.00
303_M	311_L	0.757	1.00
233_S	298_P	0.754	1.00
414_Y	417_P	0.754	1.00
415_A	419_Q	0.751	1.00
168_L	387_H	0.750	1.00
209_Y	223_D	0.750	1.00
142_M	156_F	0.750	1.00
416_Q	420_W	0.748	1.00
419_Q	422_D	0.745	1.00
322_N	326_V	0.744	1.00
67_T	70_P	0.744	1.00
289_F	296_N	0.742	1.00
283_N	286_N	0.740	1.00
232_V	237_I	0.736	1.00
290_L	294_S	0.736	1.00
181_A	184_G	0.735	1.00
455_L	460_Q	0.734	1.00
223_D	319_F	0.732	1.00
420_W	423_Y	0.732	1.00
145_Y	156_F	0.731	1.00
206_L	211_L	0.731	1.00
437_Q	440_D	0.730	1.00
436_Y	440_D	0.729	0.99
70_P	101_G	0.729	0.99
217_F	221_V	0.728	0.99
143_I	147_E	0.727	0.99
200_Y	322_N	0.726	0.99
448_F	469_W	0.725	0.99
40_T	44_S	0.725	0.99
409_N	412_D	0.724	0.99
100_A	385_L	0.724	0.99
156_F	187_L	0.723	0.99
403_A	409_N	0.723	0.99
32_G	35_A	0.722	0.99
123_A	126_Q	0.720	0.99
77_Y	131_P	0.718	0.99
213_F	353_V	0.717	0.99
328_N	332_Y	0.716	0.99
71_S	97_K	0.714	0.99
123_A	127_A	0.714	0.99
60_T	64_S	0.711	0.99
213_F	223_D	0.710	0.99
57_T	60_T	0.709	0.99
447_V	469_W	0.708	0.99
56_F	59_T	0.708	0.99
273_F	278_V	0.706	0.99
465_G	469_W	0.705	0.99
433_N	437_Q	0.704	0.99
95_A	393_Q	0.703	0.99
434_F	437_Q	0.702	0.99
202_N	315_G	0.702	0.99
207_R	210_N	0.701	0.99
208_E	234_P	0.701	0.99
172_A	177_L	0.698	0.99
34_V	37_F	0.697	0.99
17_Q	21_I	0.697	0.99
161_P	165_Q	0.696	0.99
34_V	39_L	0.694	0.99
66_T	69_T	0.691	0.99
278_V	282_I	0.690	0.99
286_N	461_V	0.687	0.99
461_V	465_G	0.686	0.99
26_V	33_V	0.685	0.99
221_V	224_T	0.684	0.99
282_I	455_L	0.684	0.99
18_I	22_V	0.684	0.99
107_Y	124_L	0.683	0.99
58_T	64_S	0.682	0.99
63_P	66_T	0.681	0.99
211_L	214_P	0.681	0.99
23_A	27_I	0.681	0.99
98_Q	101_G	0.681	0.99
35_A	39_L	0.680	0.99
166_W	383_L	0.679	0.99
165_Q	380_Q	0.678	0.99
26_V	29_I	0.676	0.99
366_L	369_D	0.676	0.99
18_I	25_I	0.675	0.99
55_T	61_T	0.673	0.99
18_I	23_A	0.671	0.99
272_N	275_N	0.669	0.99
281_L	285_T	0.668	0.99
97_K	104_M	0.668	0.99
93_I	106_T	0.668	0.99
259_G	263_Y	0.667	0.99
424_Q	427_I	0.667	0.99
407_Y	411_T	0.662	0.99
157_V	161_P	0.661	0.99
432_Q	437_Q	0.660	0.99
133_A	371_I	0.658	0.99
213_F	219_T	0.657	0.99
418_A	424_Q	0.654	0.99
299_G	311_L	0.651	0.99
84_D	87_E	0.651	0.99
462_G	466_L	0.650	0.99
278_V	452_D	0.650	0.99
124_L	131_P	0.648	0.99
64_S	68_S	0.646	0.99
348_S	351_S	0.646	0.99
388_F	391_S	0.645	0.99
433_N	436_Y	0.643	0.99
473_L	477_M	0.643	0.99
157_V	373_I	0.642	0.99
224_T	234_P	0.641	0.99
72_N	102_L	0.641	0.99
211_L	318_A	0.641	0.99
204_Q	350_V	0.640	0.99
125_I	374_P	0.639	0.99
469_W	473_L	0.638	0.99
87_E	94_P	0.636	0.99
109_I	120_A	0.636	0.99
30_I	36_G	0.636	0.99
451_I	465_G	0.635	0.99
20_V	31_I	0.635	0.99
92_I	388_F	0.635	0.99
56_F	60_T	0.634	0.99
297_Y	303_M	0.633	0.99
117_A	121_I	0.633	0.99
201_V	223_D	0.631	0.99
435_V	438_L	0.631	0.99
233_S	316_K	0.630	0.99
32_G	36_G	0.628	0.99
228_A	233_S	0.627	0.98
451_I	455_L	0.627	0.98
208_E	232_V	0.627	0.98
401_Y	407_Y	0.626	0.98
206_L	227_L	0.626	0.98
212_P	223_D	0.626	0.98
54_S	60_T	0.625	0.98
69_T	381_Q	0.624	0.98
94_P	98_Q	0.624	0.98
403_A	406_Y	0.624	0.98
435_V	439_S	0.624	0.98
252_D	256_Y	0.623	0.98
435_V	440_D	0.622	0.98
282_I	466_L	0.621	0.98
219_T	223_D	0.620	0.98
404_V	408_K	0.620	0.98
72_N	76_F	0.618	0.98
147_E	183_N	0.613	0.98
26_V	32_G	0.611	0.98
189_V	386_A	0.608	0.98
224_T	288_W	0.608	0.98
58_T	62_I	0.607	0.98
413_W	417_P	0.607	0.98
62_I	66_T	0.606	0.98
434_F	439_S	0.606	0.98
89_L	92_I	0.604	0.98
286_N	289_F	0.604	0.98
99_Y	388_F	0.602	0.98
142_M	188_S	0.601	0.98
297_Y	300_W	0.601	0.98
383_L	386_A	0.599	0.98
24_V	28_V	0.599	0.98
308_A	317_V	0.597	0.98
95_A	394_G	0.596	0.98
419_Q	426_L	0.595	0.98
209_Y	318_A	0.591	0.98
416_Q	419_Q	0.591	0.98
142_M	146_V	0.590	0.98
25_I	32_G	0.590	0.98
163_L	166_W	0.590	0.98
299_G	302_S	0.590	0.98
427_I	430_S	0.585	0.98
39_L	42_G	0.585	0.98
372_G	375_V	0.585	0.98
33_V	37_F	0.584	0.98
373_I	382_A	0.582	0.98
24_V	27_I	0.582	0.98
159_M	186_L	0.582	0.98
432_Q	439_S	0.581	0.98
250_W	253_I	0.581	0.98
447_V	455_L	0.581	0.98
77_Y	107_Y	0.580	0.97
22_V	32_G	0.580	0.97
141_E	145_Y	0.580	0.97
18_I	33_V	0.579	0.97
291_N	294_S	0.578	0.97
225_V	287_Y	0.578	0.97
415_A	418_A	0.578	0.97
271_L	474_V	0.578	0.97
122_L	144_S	0.576	0.97
438_L	441_G	0.574	0.97
290_L	458_L	0.574	0.97
173_V	177_L	0.574	0.97
220_L	235_W	0.572	0.97
57_T	63_P	0.572	0.97
164_I	167_G	0.571	0.97
74_V	381_Q	0.571	0.97
475_S	478_Q	0.571	0.97
144_S	148_A	0.571	0.97
69_T	72_N	0.570	0.97
231_G	236_I	0.569	0.97
432_Q	436_Y	0.569	0.97
232_V	316_K	0.569	0.97
203_T	213_F	0.567	0.97
393_Q	397_V	0.567	0.97
150_P	158_N	0.567	0.97
455_L	469_W	0.567	0.97
475_S	479_Q	0.567	0.97
277_T	281_L	0.567	0.97
248_N	252_D	0.566	0.97
282_I	465_G	0.565	0.97
303_M	307_Q	0.565	0.97
402_K	405_T	0.564	0.97
213_F	355_T	0.564	0.97
59_T	63_P	0.563	0.97
228_A	231_G	0.563	0.97
435_V	441_G	0.563	0.97
22_V	33_V	0.563	0.97
22_V	29_I	0.562	0.97
21_I	24_V	0.561	0.97
29_I	36_G	0.561	0.97
56_F	61_T	0.560	0.97
233_S	237_I	0.560	0.97
312_I	317_V	0.560	0.97
174_Y	177_L	0.560	0.97
274_S	463_K	0.559	0.97
249_V	253_I	0.559	0.97
206_L	213_F	0.559	0.97
76_F	135_Q	0.558	0.97
61_T	65_T	0.558	0.97
403_A	408_K	0.557	0.97
274_S	466_L	0.556	0.97
454_G	458_L	0.555	0.97
157_V	376_G	0.555	0.97
27_I	36_G	0.554	0.97
96_V	100_A	0.554	0.97
211_L	222_Y	0.553	0.97
436_Y	439_S	0.553	0.97
177_L	181_A	0.553	0.97
146_V	149_A	0.552	0.97
423_Y	426_L	0.551	0.97
136_V	156_F	0.550	0.97
254_F	258_A	0.550	0.97
310_A	313_A	0.549	0.97
218_S	284_E	0.548	0.96
353_V	356_P	0.548	0.96
171_N	408_K	0.548	0.96
433_N	440_D	0.547	0.96
111_G	116_N	0.547	0.96
309_F	326_V	0.546	0.96
271_L	470_N	0.545	0.96
206_L	318_A	0.545	0.96
110_P	115_T	0.544	0.96
462_G	465_G	0.544	0.96
77_Y	117_A	0.544	0.96
23_A	30_I	0.544	0.96
86_G	89_L	0.542	0.96
89_L	94_P	0.541	0.96
93_I	104_M	0.541	0.96
311_L	317_V	0.539	0.96
402_K	406_Y	0.537	0.96
201_V	213_F	0.536	0.96
274_S	474_V	0.536	0.96
220_L	288_W	0.535	0.96
275_N	278_V	0.535	0.96
97_K	105_Q	0.535	0.96
216_N	220_L	0.534	0.96
442_G	446_D	0.532	0.96
92_I	96_V	0.531	0.96
173_V	409_N	0.530	0.96
235_W	240_G	0.530	0.96
60_T	66_T	0.529	0.96
419_Q	424_Q	0.528	0.96
420_W	426_L	0.528	0.96
75_V	131_P	0.528	0.96
70_P	377_P	0.528	0.96
19_A	29_I	0.527	0.96
159_M	162_Y	0.527	0.96
119_Y	122_L	0.527	0.96
396_E	411_T	0.525	0.96
157_V	160_T	0.524	0.95
103_Q	106_T	0.522	0.95
101_G	384_Q	0.522	0.95
380_Q	383_L	0.521	0.95
70_P	73_T	0.520	0.95
21_I	25_I	0.520	0.95
75_V	129_K	0.520	0.95
68_S	71_S	0.519	0.95
53_T	56_F	0.518	0.95
406_Y	409_N	0.518	0.95
89_L	93_I	0.518	0.95
214_P	319_F	0.516	0.95
59_T	62_I	0.516	0.95
437_Q	441_G	0.516	0.95
85_G	89_L	0.515	0.95
306_E	309_F	0.514	0.95
56_F	62_I	0.513	0.95
227_L	319_F	0.513	0.95
116_N	120_A	0.513	0.95
306_E	310_A	0.513	0.95
454_G	468_A	0.513	0.95
71_S	99_Y	0.512	0.95
18_I	31_I	0.510	0.95
77_Y	121_I	0.510	0.95
132_A	377_P	0.508	0.95
424_Q	429_T	0.508	0.95
202_N	351_S	0.508	0.95
421_Y	430_S	0.508	0.95
420_W	427_I	0.507	0.95
407_Y	410_G	0.506	0.95
96_V	381_Q	0.505	0.95
397_V	402_K	0.504	0.94
371_I	386_A	0.504	0.94
92_I	397_V	0.502	0.94
92_I	394_G	0.502	0.94
201_V	319_F	0.501	0.94
248_N	251_E	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r2fA	1	0.6787	100	0.409	Contact Map
4r9fA	1	0.6715	100	0.443	Contact Map
4mfiA	1	0.6913	100	0.447	Contact Map
3vxbA	1	0.6769	100	0.448	Contact Map
3uorA	1	0.6968	100	0.455	Contact Map
4g68A	1	0.6841	100	0.463	Contact Map
4c1uA	1	0.6895	100	0.467	Contact Map
4r6kA	1	0.6805	100	0.469	Contact Map
2w7yA	1	0.6625	100	0.477	Contact Map
4r6hA	1	0.6787	100	0.482	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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