GREMLIN Database
Q97UX7 - Uncharacterized protein
UniProt: Q97UX7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 192 (179)
Sequences: 1234 (878)
Seq/√Len: 65.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
64_E69_N3.1671.00
61_G77_F3.1651.00
79_Y113_T3.0261.00
129_M166_A2.8221.00
85_W105_V2.7721.00
139_F143_V2.7251.00
110_G139_F2.6881.00
31_S160_G2.4711.00
112_F116_M2.4581.00
144_G153_S2.4531.00
51_F84_E2.4401.00
117_W128_F2.4071.00
107_I142_G2.3541.00
117_W132_L2.3241.00
52_Y78_T2.2981.00
21_S171_G2.2871.00
140_L159_V2.2681.00
29_V48_L2.1831.00
24_A167_A2.1581.00
136_I140_L2.1531.00
114_L135_W2.1301.00
126_G170_T2.1041.00
110_G142_G2.0081.00
59_L62_I2.0061.00
158_Y162_L1.9451.00
137_T160_G1.7661.00
107_I146_M1.7361.00
151_G155_A1.7261.00
114_L118_F1.6930.99
133_L162_L1.6850.99
35_A158_Y1.6840.99
25_L168_W1.6710.99
117_W135_W1.6150.99
75_A131_F1.6150.99
121_F128_F1.5880.99
62_I77_F1.5590.99
63_L73_Y1.5210.99
19_G60_A1.4990.99
136_I159_V1.4940.99
99_P145_A1.4920.99
150_V154_H1.4710.98
32_T37_L1.4710.98
137_T163_T1.4680.98
105_V109_F1.4490.98
133_L166_A1.4470.98
103_G146_M1.4460.98
145_A153_S1.4270.98
24_A164_A1.4080.98
28_L168_W1.3630.97
65_W73_Y1.3590.97
124_N186_V1.3410.97
58_L81_A1.3390.97
54_G80_G1.3300.97
117_W121_F1.3230.97
133_L163_T1.3140.97
130_T166_A1.2770.96
120_T131_F1.2380.95
115_A172_L1.2330.95
128_F132_L1.2110.95
149_N152_L1.1930.94
117_W120_T1.1860.94
48_L85_W1.1820.94
142_G146_M1.1790.94
56_A81_A1.1720.94
143_V152_L1.1600.93
58_L77_F1.1580.93
106_L156_G1.1560.93
129_M133_L1.1400.93
126_G130_T1.1370.93
82_F138_F1.1270.92
70_T74_T1.1180.92
134_L163_T1.1160.92
140_L155_A1.1130.92
92_G95_G1.1070.92
120_T128_F1.0920.91
88_L91_G1.0920.91
71_F75_A1.0850.91
21_S168_W1.0840.91
69_N72_G1.0830.91
162_L166_A1.0800.91
31_S137_T1.0780.91
125_L128_F1.0750.91
50_A88_L1.0700.90
104_L146_M1.0560.90
116_M175_V1.0560.90
76_F127_L1.0510.90
34_N75_A1.0370.89
150_V153_S1.0240.88
35_A161_I1.0200.88
113_T134_L1.0160.88
110_G135_W1.0080.87
115_A171_G1.0050.87
144_G156_G1.0020.87
12_R67_A1.0010.87
131_F138_F0.9960.87
32_T161_I0.9830.86
114_L117_W0.9800.86
16_A124_N0.9780.86
36_G150_V0.9760.86
129_M162_L0.9730.86
28_L164_A0.9720.86
123_A127_L0.9710.85
141_L156_G0.9690.85
86_Y145_A0.9680.85
25_L108_A0.9600.85
16_A64_E0.9550.84
100_Q146_M0.9480.84
119_G176_V0.9400.84
103_G107_I0.9320.83
12_R65_W0.9210.82
83_W134_L0.9020.81
28_L32_T0.8950.80
177_A183_S0.8880.80
137_T159_V0.8870.80
22_G56_A0.8830.80
140_L152_L0.8790.79
89_T96_G0.8740.79
113_T135_W0.8730.79
41_G44_V0.8650.78
28_L108_A0.8500.77
13_A18_L0.8290.75
34_N167_A0.8250.75
78_T109_F0.8230.75
30_L106_L0.8110.73
80_G84_E0.8090.73
125_L187_G0.8060.73
36_G40_Q0.8030.73
78_T112_F0.8000.72
61_G80_G0.7990.72
57_Q113_T0.7940.72
17_P70_T0.7940.72
30_L82_F0.7930.72
12_R63_L0.7920.72
130_T170_T0.7920.72
154_H158_Y0.7860.71
75_A141_L0.7780.70
135_W139_F0.7750.70
29_V108_A0.7720.70
57_Q167_A0.7710.70
25_L187_G0.7700.70
159_V162_L0.7690.69
13_A67_A0.7600.69
83_W169_Y0.7570.68
13_A178_E0.7460.67
106_L141_L0.7450.67
176_V184_P0.7450.67
110_G143_V0.7420.67
123_A179_S0.7390.66
111_I115_A0.7350.66
163_T166_A0.7340.66
56_A60_A0.7330.66
170_T174_I0.7230.65
71_F120_T0.7220.65
87_F91_G0.7210.64
36_G86_Y0.7130.64
126_G187_G0.7080.63
35_A157_G0.7070.63
152_L155_A0.7060.63
173_A183_S0.7020.62
107_I139_F0.7010.62
34_N160_G0.7010.62
20_L27_T0.6980.62
92_G96_G0.6950.62
144_G149_N0.6950.62
27_T57_Q0.6920.61
90_A93_F0.6890.61
173_A186_V0.6820.60
127_L170_T0.6770.60
27_T83_W0.6730.59
20_L23_F0.6670.58
55_L89_T0.6670.58
132_L135_W0.6650.58
33_F101_A0.6640.58
108_A164_A0.6630.58
50_A81_A0.6630.58
172_L184_P0.6620.58
33_F43_S0.6600.58
177_A182_K0.6600.58
170_T186_V0.6570.57
89_T97_V0.6510.57
27_T160_G0.6510.57
10_Q65_W0.6460.56
10_Q67_A0.6460.56
95_G98_T0.6450.56
108_A111_I0.6430.56
124_N187_G0.6420.56
161_I165_I0.6420.56
13_A17_P0.6420.56
123_A174_I0.6400.55
173_A184_P0.6400.55
54_G84_E0.6390.55
158_Y161_I0.6370.55
58_L80_G0.6330.55
24_A28_L0.6270.54
34_N72_G0.6270.54
133_L159_V0.6250.54
87_F185_P0.6230.53
76_F184_P0.6230.53
24_A77_F0.6190.53
27_T31_S0.6190.53
13_A70_T0.6180.53
30_L138_F0.6180.53
39_T97_V0.6160.53
113_T138_F0.6080.52
30_L141_L0.6070.51
32_T105_V0.6010.51
107_I127_L0.5920.50
84_E135_W0.5920.50
75_A137_T0.5910.50
86_Y102_I0.5880.49
137_T156_G0.5870.49
126_G165_I0.5860.49
41_G95_G0.5860.49
30_L157_G0.5860.49
60_A113_T0.5840.49
11_K68_G0.5840.49
91_G176_V0.5820.49
159_V163_T0.5780.48
38_I101_A0.5770.48
47_G93_F0.5760.48
59_L73_Y0.5760.48
180_L183_S0.5750.48
168_W171_G0.5730.47
129_M143_V0.5720.47
174_I186_V0.5710.47
17_P31_S0.5700.47
21_S24_A0.5650.47
59_L89_T0.5640.46
58_L79_Y0.5610.46
33_F45_V0.5600.46
111_I165_I0.5590.46
34_N157_G0.5580.46
134_L167_A0.5570.46
100_Q186_V0.5550.45
21_S25_L0.5530.45
118_F121_F0.5520.45
145_A152_L0.5520.45
31_S34_N0.5500.45
97_V101_A0.5470.44
52_Y81_A0.5470.44
62_I65_W0.5460.44
170_T184_P0.5450.44
59_L63_L0.5440.44
15_P72_G0.5430.44
75_A116_M0.5410.44
22_G171_G0.5410.44
112_F168_W0.5410.44
58_L62_I0.5360.43
58_L66_R0.5330.43
38_I154_H0.5320.43
131_F175_V0.5310.43
81_A169_Y0.5300.42
15_P34_N0.5290.42
43_S89_T0.5260.42
119_G172_L0.5190.41
33_F161_I0.5170.41
94_F98_T0.5170.41
123_A170_T0.5150.41
29_V45_V0.5130.41
32_T108_A0.5120.40
155_A159_V0.5120.40
27_T138_F0.5070.40
82_F141_L0.5070.40
21_S52_Y0.5070.40
24_A168_W0.5060.40
27_T82_F0.5060.40
55_L136_I0.5040.40
35_A110_G0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ux4A 3 0.8229 3.7 0.959 Contact Map
3uf7A 1 0.2656 3.5 0.96 Contact Map
3wdfA 1 0.2604 2.7 0.962 Contact Map
2y69K 1 0.2552 2.5 0.963 Contact Map
1v54K 1 0.2552 2.4 0.963 Contact Map
1jb0K 1 0.1198 1.7 0.966 Contact Map
4ogqG 1 0.1927 1.6 0.966 Contact Map
1q90G 1 0.1562 1.5 0.967 Contact Map
1aluA 2 0.3073 1.5 0.967 Contact Map
2l3yA 1 0.3073 1.5 0.967 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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