Q97UV9 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97UV9 - Oxidoreductase

UniProt:	Q97UV9	Sequences: MEKKPLGWTNEKISPLILGSWEFGTPSIIDENNAIKAIQRAIELGINAIDTAESYGNGLSETIIGRAISKFKREDLFIITKVSIDHLRYDDVLKASEGSLKRLNTSYIDLYLVHWPNHYVPIRETAKAMERLFNEGKIRYVGLSNFSLPLMREFREHLSKTDVAANELHYNVLFRDVEKEVLPYMLRENIPLLAYDALGLGYLIGRKEVRNEYRWYVLARETYIKNLEPLIEEISSIAKELGKTPAQVVLNWLVSKDNVFAIFNTTKEDHLKENLGSLGWSLRDSDLRRLDEAVKKVTIDYFAR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	304 (264)
Sequences:	32413 (20856)
Seq/√Len:	1283.6

ECOLI - YDJG YAJO YEAE GPR YDHF TAS DKGA YDBC DKGB
BACSU - IOLS GS69 YRPG YCCK YCSN YQKF YTBE GR
HALSA - Q9HPH9 Q9HNN3 Q9HQU7 Q9HS02 Q9HSE6 Q9HQT1
SULSO - Q97UV9 Q97UG6 Q97ZZ1 Q97UJ7 Q97V56 Q97U17

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
40_R	272_K	3.170	1.00
97_E	137_K	2.997	1.00
31_E	66_R	2.929	1.00
69_S	104_N	2.835	1.00
241_L	286_D	2.769	1.00
96_S	132_L	2.528	1.00
35_I	70_K	2.498	1.00
283_R	286_D	2.489	1.00
5_P	12_K	2.459	1.00
93_L	131_R	2.424	1.00
93_L	135_E	2.401	1.00
40_R	44_L	2.328	1.00
240_E	289_R	2.217	1.00
235_S	239_K	2.079	1.00
130_E	134_N	2.073	1.00
35_I	66_R	2.060	1.00
240_E	286_D	2.042	1.00
255_S	287_L	2.036	1.00
98_G	102_R	1.997	1.00
284_D	288_R	1.977	1.00
107_Y	139_R	1.973	1.00
131_R	135_E	1.954	1.00
184_Y	188_E	1.949	1.00
236_S	289_R	1.919	1.00
72_K	75_D	1.903	1.00
268_E	272_K	1.889	1.00
185_M	192_L	1.871	1.00
191_P	260_F	1.829	1.00
17_I	48_A	1.810	1.00
78_I	105_T	1.808	1.00
40_R	268_E	1.797	1.00
89_Y	131_R	1.768	1.00
112_L	165_A	1.767	1.00
131_R	134_N	1.746	1.00
256_K	291_D	1.738	1.00
44_L	272_K	1.735	1.00
243_K	280_W	1.721	1.00
80_T	108_I	1.711	1.00
89_Y	93_L	1.653	1.00
251_N	280_W	1.653	1.00
62_T	102_R	1.649	1.00
44_L	275_L	1.640	1.00
41_A	46_I	1.632	1.00
30_D	33_N	1.629	1.00
233_E	236_S	1.621	1.00
288_R	292_E	1.618	1.00
82_V	111_Y	1.616	1.00
80_T	99_S	1.614	1.00
35_I	67_A	1.609	1.00
35_I	39_Q	1.600	1.00
152_R	184_Y	1.598	1.00
244_T	273_E	1.596	1.00
82_V	92_V	1.585	1.00
96_S	111_Y	1.580	1.00
276_G	279_G	1.573	1.00
40_R	43_E	1.569	1.00
93_L	97_E	1.560	1.00
134_N	160_K	1.548	1.00
79_I	112_L	1.545	1.00
39_Q	70_K	1.544	1.00
128_A	131_R	1.541	1.00
130_E	161_T	1.503	1.00
20_S	49_I	1.498	1.00
11_E	140_Y	1.489	1.00
53_E	95_A	1.455	1.00
108_I	138_I	1.446	1.00
112_L	193_L	1.443	1.00
94_K	98_G	1.436	1.00
243_K	247_Q	1.436	1.00
183_P	187_R	1.430	1.00
42_I	76_L	1.417	1.00
186_L	258_N	1.409	1.00
147_S	150_L	1.400	1.00
97_E	101_K	1.397	1.00
180_E	183_P	1.388	1.00
33_N	36_K	1.385	1.00
133_F	161_T	1.360	1.00
272_K	276_G	1.360	1.00
31_E	35_I	1.359	1.00
38_I	67_A	1.354	1.00
89_Y	127_K	1.327	1.00
168_L	192_L	1.325	1.00
251_N	255_S	1.322	1.00
11_E	77_F	1.313	1.00
39_Q	43_E	1.298	1.00
98_G	101_K	1.287	1.00
289_R	292_E	1.286	1.00
140_Y	164_A	1.284	1.00
93_L	128_A	1.281	1.00
132_L	138_I	1.276	1.00
243_K	248_V	1.274	1.00
138_I	141_V	1.267	1.00
236_S	240_E	1.266	1.00
89_Y	128_A	1.264	1.00
36_K	40_R	1.264	1.00
233_E	289_R	1.259	1.00
77_F	110_L	1.227	1.00
265_T	270_H	1.223	1.00
66_R	104_N	1.217	1.00
244_T	247_Q	1.208	1.00
96_S	108_I	1.203	1.00
265_T	271_L	1.201	1.00
49_I	64_I	1.190	1.00
182_L	186_L	1.190	1.00
148_L	184_Y	1.181	1.00
65_G	104_N	1.179	1.00
103_L	108_I	1.179	1.00
152_R	187_R	1.174	1.00
73_R	105_T	1.173	1.00
269_D	272_K	1.172	1.00
61_E	99_S	1.172	1.00
152_R	156_E	1.167	1.00
73_R	107_Y	1.167	1.00
237_I	248_V	1.162	1.00
110_L	165_A	1.155	1.00
116_P	150_L	1.130	1.00
235_S	245_P	1.119	1.00
62_T	66_R	1.117	1.00
172_V	290_L	1.117	1.00
90_D	94_K	1.117	1.00
9_T	140_Y	1.111	1.00
32_N	36_K	1.110	1.00
130_E	160_K	1.107	1.00
48_A	193_L	1.106	1.00
152_R	188_E	1.104	1.00
88_R	91_D	1.104	1.00
91_D	94_K	1.103	1.00
124_E	127_K	1.099	1.00
97_E	135_E	1.097	1.00
37_A	271_L	1.092	1.00
129_M	141_V	1.089	1.00
232_E	236_S	1.075	1.00
48_A	79_I	1.071	1.00
39_Q	67_A	1.069	1.00
133_F	164_A	1.064	1.00
169_H	174_F	1.064	1.00
130_E	133_F	1.048	1.00
148_L	152_R	1.046	1.00
175_R	294_V	1.046	1.00
236_S	239_K	1.038	1.00
247_Q	276_G	1.037	1.00
47_N	77_F	1.035	1.00
20_S	64_I	1.032	1.00
234_I	245_P	1.030	1.00
8_W	164_A	1.029	1.00
170_Y	256_K	1.023	1.00
232_E	235_S	1.022	1.00
113_V	129_M	1.021	1.00
36_K	268_E	1.021	1.00
254_V	277_S	1.015	1.00
123_R	153_E	1.000	1.00
89_Y	124_E	0.997	1.00
186_L	257_D	0.996	1.00
132_L	137_K	0.992	1.00
62_T	101_K	0.990	1.00
66_R	70_K	0.989	1.00
14_S	47_N	0.986	1.00
5_P	10_N	0.977	1.00
172_V	249_V	0.970	1.00
271_L	275_L	0.969	1.00
183_P	186_L	0.967	1.00
165_A	193_L	0.963	1.00
155_R	184_Y	0.961	1.00
143_L	163_V	0.958	1.00
127_K	131_R	0.951	1.00
14_S	46_I	0.947	1.00
68_I	76_L	0.941	1.00
109_D	139_R	0.940	1.00
61_E	102_R	0.931	1.00
179_K	183_P	0.925	1.00
15_P	254_V	0.925	1.00
273_E	276_G	0.922	1.00
155_R	188_E	0.921	1.00
87_L	113_V	0.920	1.00
132_L	135_E	0.919	1.00
143_L	151_M	0.918	1.00
247_Q	273_E	0.918	1.00
9_T	164_A	0.904	1.00
123_R	157_H	0.904	1.00
269_D	273_E	0.903	1.00
53_E	91_D	0.903	1.00
79_I	193_L	0.893	1.00
128_A	132_L	0.892	1.00
94_K	97_E	0.891	1.00
166_N	185_M	0.888	1.00
288_R	291_D	0.886	1.00
93_L	96_S	0.882	1.00
250_L	277_S	0.877	1.00
38_I	49_I	0.872	1.00
285_S	288_R	0.871	1.00
15_P	278_L	0.871	1.00
255_S	281_S	0.867	1.00
42_I	72_K	0.862	1.00
155_R	158_L	0.862	1.00
130_E	141_V	0.857	1.00
267_K	270_H	0.856	1.00
141_V	163_V	0.855	1.00
285_S	289_R	0.852	1.00
20_S	60_S	0.850	1.00
127_K	130_E	0.850	1.00
36_K	39_Q	0.847	1.00
184_Y	187_R	0.839	1.00
256_K	287_L	0.835	1.00
240_E	283_R	0.835	1.00
145_N	195_Y	0.832	1.00
237_I	241_L	0.832	1.00
93_L	132_L	0.831	1.00
86_H	91_D	0.826	1.00
241_L	283_R	0.825	1.00
79_I	110_L	0.823	1.00
9_T	133_F	0.816	1.00
175_R	291_D	0.811	1.00
18_L	41_A	0.797	1.00
100_L	137_K	0.794	1.00
182_L	192_L	0.791	1.00
251_N	277_S	0.786	1.00
151_M	190_I	0.786	1.00
249_V	253_L	0.775	1.00
255_S	284_D	0.770	1.00
170_Y	182_L	0.768	1.00
115_W	145_N	0.767	1.00
53_E	102_R	0.766	1.00
208_E	235_S	0.761	1.00
53_E	86_H	0.761	1.00
233_E	293_A	0.757	1.00
18_L	23_F	0.757	1.00
80_T	111_Y	0.756	1.00
148_L	181_V	0.751	1.00
126_A	154_F	0.748	1.00
44_L	276_G	0.745	1.00
40_R	271_L	0.743	1.00
51_T	64_I	0.739	1.00
194_A	197_A	0.738	1.00
126_A	163_V	0.732	1.00
17_I	263_F	0.728	1.00
100_L	105_T	0.720	1.00
197_A	263_F	0.719	1.00
53_E	98_G	0.717	1.00
143_L	166_N	0.717	1.00
181_V	185_M	0.712	1.00
175_R	178_E	0.707	1.00
252_W	291_D	0.707	1.00
243_K	279_G	0.706	1.00
32_N	35_I	0.706	1.00
37_A	268_E	0.701	1.00
96_S	137_K	0.700	1.00
92_V	132_L	0.699	1.00
16_L	254_V	0.697	1.00
74_E	107_Y	0.696	1.00
248_V	280_W	0.695	1.00
148_L	180_E	0.694	1.00
46_I	275_L	0.693	1.00
34_A	63_I	0.692	1.00
126_A	141_V	0.692	1.00
185_M	190_I	0.689	1.00
143_L	146_F	0.689	1.00
237_I	286_D	0.689	1.00
209_V	232_E	0.689	1.00
42_I	49_I	0.688	1.00
257_D	261_A	0.687	1.00
241_L	248_V	0.685	1.00
99_S	111_Y	0.682	1.00
92_V	125_T	0.680	1.00
266_T	270_H	0.677	1.00
282_L	287_L	0.677	1.00
234_I	249_V	0.674	1.00
47_N	75_D	0.672	1.00
95_A	98_G	0.672	1.00
239_K	242_G	0.670	1.00
44_L	271_L	0.663	1.00
182_L	256_K	0.663	1.00
234_I	290_L	0.662	1.00
11_E	139_R	0.662	1.00
155_R	162_D	0.662	1.00
38_I	42_I	0.660	1.00
243_K	276_G	0.658	1.00
39_Q	72_K	0.658	1.00
270_H	273_E	0.654	1.00
125_T	128_A	0.653	1.00
246_A	273_E	0.653	1.00
117_N	120_V	0.648	1.00
197_A	253_L	0.648	1.00
54_S	83_S	0.644	1.00
170_Y	259_V	0.643	1.00
248_V	282_L	0.643	1.00
23_F	37_A	0.640	1.00
87_L	125_T	0.639	1.00
178_E	183_P	0.639	1.00
243_K	251_N	0.639	1.00
21_W	196_D	0.638	1.00
130_E	158_L	0.637	1.00
170_Y	253_L	0.631	1.00
133_F	140_Y	0.629	1.00
112_L	142_G	0.629	1.00
25_T	63_I	0.628	1.00
238_A	248_V	0.627	1.00
253_L	259_V	0.626	1.00
193_L	260_F	0.624	1.00
33_N	268_E	0.621	1.00
238_A	245_P	0.621	1.00
237_I	289_R	0.620	1.00
133_F	138_I	0.619	1.00
96_S	100_L	0.618	1.00
129_M	133_F	0.615	1.00
92_V	128_A	0.611	1.00
22_E	200_L	0.611	1.00
13_I	260_F	0.610	1.00
108_I	111_Y	0.609	1.00
72_K	76_L	0.608	1.00
256_K	259_V	0.607	1.00
170_Y	192_L	0.606	1.00
231_I	235_S	0.606	1.00
122_I	125_T	0.605	1.00
208_E	232_E	0.605	1.00
43_E	268_E	0.605	1.00
202_Y	231_I	0.603	1.00
282_L	286_D	0.599	1.00
88_R	125_T	0.596	1.00
175_R	179_K	0.595	1.00
93_L	137_K	0.595	1.00
156_E	162_D	0.594	1.00
37_A	265_T	0.594	1.00
153_E	157_H	0.593	1.00
71_F	76_L	0.593	1.00
6_L	191_P	0.591	1.00
100_L	108_I	0.587	1.00
194_A	259_V	0.585	1.00
286_D	289_R	0.582	1.00
150_L	153_E	0.577	1.00
248_V	286_D	0.575	1.00
123_R	127_K	0.575	1.00
31_E	63_I	0.573	1.00
238_A	241_L	0.573	1.00
170_Y	175_R	0.570	1.00
111_Y	138_I	0.568	1.00
127_K	160_K	0.567	1.00
205_G	208_E	0.567	1.00
100_L	107_Y	0.567	1.00
8_W	162_D	0.565	1.00
155_R	160_K	0.562	1.00
50_D	167_E	0.562	1.00
42_I	47_N	0.562	1.00
17_I	262_I	0.560	1.00
38_I	64_I	0.559	1.00
173_L	202_Y	0.558	1.00
13_I	48_A	0.558	1.00
237_I	293_A	0.557	1.00
53_E	83_S	0.555	1.00
89_Y	92_V	0.553	1.00
23_F	34_A	0.553	1.00
247_Q	280_W	0.552	1.00
42_I	75_D	0.551	1.00
82_V	95_A	0.549	1.00
172_V	252_W	0.548	1.00
8_W	189_N	0.545	1.00
248_V	290_L	0.545	1.00
196_D	200_L	0.544	1.00
149_P	152_R	0.542	1.00
49_I	68_I	0.542	1.00
6_L	9_T	0.541	1.00
111_Y	129_M	0.541	1.00
100_L	106_S	0.540	1.00
113_V	125_T	0.539	1.00
84_I	87_L	0.537	1.00
143_L	154_F	0.532	1.00
82_V	87_L	0.531	1.00
18_L	37_A	0.530	1.00
66_R	69_S	0.530	1.00
204_I	207_K	0.530	1.00
241_L	280_W	0.529	1.00
122_I	153_E	0.528	1.00
182_L	259_V	0.528	1.00
84_I	115_W	0.527	1.00
154_F	163_V	0.527	1.00
48_A	77_F	0.527	1.00
251_N	281_S	0.527	1.00
16_L	278_L	0.526	1.00
64_I	67_A	0.526	1.00
61_E	80_T	0.522	1.00
277_S	280_W	0.520	1.00
122_I	150_L	0.519	1.00
151_M	185_M	0.518	1.00
24_G	60_S	0.514	1.00
96_S	128_A	0.514	1.00
209_V	225_K	0.513	1.00
73_R	109_D	0.513	1.00
168_L	181_V	0.512	1.00
152_R	155_R	0.509	1.00
23_F	264_N	0.507	1.00
268_E	271_L	0.507	1.00
170_Y	178_E	0.506	1.00
141_V	161_T	0.506	1.00
134_N	161_T	0.505	1.00
42_I	67_A	0.503	1.00
68_I	72_K	0.503	1.00
237_I	240_E	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pyfA	1	0.9638	100	0.077	Contact Map
1pz1A	1	0.9901	100	0.085	Contact Map
4xk2A	5	0.9441	100	0.088	Contact Map
3n2tA	1	0.9836	100	0.09	Contact Map
3v0sA	1	0.8618	100	0.095	Contact Map
3eauA	3	0.9803	100	0.101	Contact Map
1lqaA	2	0.9868	100	0.101	Contact Map
3lutA	3	0.977	100	0.108	Contact Map
3erpA	6	0.9309	100	0.109	Contact Map
4r9oA	5	0.9112	100	0.111	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0096 seconds.