Q97UT4 - SULSO - GREMLIN Contacts

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Q97UT4 - Sulfite reductase hemoprotein beta component (CysI)

UniProt:	Q97UT4	Sequences: MKIPIEPNFRTDPKDYSEEERAKLKTKGLTEDTIGIYSSFHDLSREDLEKEVSLIAKSFGIYIEFNRDKMKLNGVKDWIYMVRLPIPGGGPISSKQWRILDDISNKYTISDAYTGYPSPSLKLTTRQAIQFHHVKKRDLPNLIREVAESGFLTVNGCGDNVRNTIACPLSKYWVFDANSLARKIANYFRLPLDLYLQVFEIPLIENRQFDRESFKYGENLLPRKFKIAIAGVLRTINGKYIIDNCVEVQSNDIGIVPLIEDEKVIGYQIYVGGSMGENNSYPTFSALGLPIGTVVNDSELIKVLDAIVTIQEEWGDRKNRHWARFKYVVYKMGLEWLREKVREHSGIQLGKIVKVDLTHKDLHLGWINLGDNKWAYGIFVENGRLIDGKNGRTKSMIRYIADNFDNLMFYITPNQHLLITEIDQPQKEKIDGILREFNYGFRDGKPYSSLRINSTACVGFPTCKLSFTDSERFLPSLIDELERRGWKDIPVSIGLSGCVAQCSRPALHPISWVGSGYELYMLKIGGGNGSLGEPLIDWDENSIYLYQVPSNRLADVTEALFELYEKNKDISEDPSLVFRLLGNKKIIEWLKGHEKTKDLMKPHKFDRKIEGYREYHDLLRKRLEEVSRYG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	630 (495)
Sequences:	2285 (1173)
Seq/√Len:	52.7

ECOLI - CYSI
BACSU - CYSI
SULSO - Q97UT4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
374_W	424_Q	4.846	1.00
105_N	395_S	4.471	1.00
340_K	343_E	4.433	1.00
336_W	339_E	4.416	1.00
102_D	106_K	4.073	1.00
572_E	580_L	3.415	1.00
98_R	402_D	3.343	1.00
332_M	336_W	3.315	1.00
180_L	267_Y	3.289	1.00
299_E	347_I	3.194	1.00
266_G	294_V	3.183	1.00
316_D	322_W	3.147	1.00
253_I	307_I	3.095	1.00
496_S	503_S	3.019	1.00
255_I	269_I	3.018	1.00
423_D	426_Q	2.998	1.00
397_I	417_L	2.979	1.00
255_I	304_L	2.939	1.00
286_A	289_L	2.877	1.00
335_E	338_R	2.803	1.00
485_G	489_I	2.785	1.00
296_N	299_E	2.782	1.00
135_K	138_D	2.770	1.00
106_K	145_E	2.748	1.00
486_W	489_I	2.735	1.00
225_F	308_V	2.673	1.00
184_I	304_L	2.639	1.00
485_G	488_D	2.615	1.00
21_R	25_K	2.612	1.00
167_C	245_C	2.602	1.00
563_L	567_N	2.555	1.00
408_M	421_E	2.478	1.00
422_I	430_I	2.474	1.00
123_L	417_L	2.471	1.00
99_I	145_E	2.440	1.00
123_L	411_I	2.429	1.00
84_L	131_F	2.401	1.00
184_I	229_I	2.378	1.00
368_N	424_Q	2.307	1.00
26_T	30_T	2.293	1.00
164_T	184_I	2.293	1.00
98_R	399_Y	2.292	1.00
337_L	341_V	2.225	1.00
107_Y	141_N	2.214	1.00
549_P	552_R	2.206	1.00
292_G	295_V	2.199	1.00
534_P	579_R	2.155	1.00
253_I	304_L	2.142	1.00
26_T	150_G	2.126	1.00
107_Y	145_E	2.114	1.00
270_Y	290_P	2.108	1.00
229_I	255_I	2.106	1.00
368_N	374_W	2.102	1.00
306_A	341_V	2.093	1.00
399_Y	402_D	2.078	1.00
573_D	576_L	2.076	1.00
378_I	434_L	2.055	1.00
428_E	432_G	2.036	1.00
409_F	417_L	2.030	1.00
260_E	264_V	2.008	1.00
426_Q	429_K	2.007	1.00
522_L	548_V	1.988	1.00
322_W	331_K	1.971	1.00
366_W	374_W	1.963	1.00
484_R	488_D	1.960	1.00
403_N	433_I	1.957	1.00
336_W	340_K	1.948	1.00
182_R	186_N	1.942	1.00
260_E	263_K	1.939	1.00
400_I	433_I	1.937	1.00
102_D	395_S	1.886	0.99
454_S	474_L	1.882	0.99
548_V	556_V	1.869	0.99
310_I	341_V	1.856	0.99
250_S	507_L	1.843	0.99
100_L	131_F	1.842	0.99
99_I	148_E	1.811	0.99
376_Y	430_I	1.792	0.99
19_E	54_L	1.785	0.99
164_T	181_A	1.783	0.99
119_P	392_R	1.782	0.99
339_E	343_E	1.770	0.99
412_T	418_L	1.769	0.99
299_E	302_K	1.765	0.99
228_A	246_V	1.763	0.99
340_K	344_H	1.735	0.99
228_A	251_N	1.730	0.99
18_E	21_R	1.716	0.99
484_R	487_K	1.695	0.99
314_W	340_K	1.693	0.99
46_E	78_W	1.693	0.99
396_M	437_F	1.685	0.99
268_Q	290_P	1.682	0.99
367_I	375_A	1.675	0.99
61_I	139_L	1.664	0.99
180_L	297_D	1.656	0.98
94_S	402_D	1.654	0.98
286_A	330_Y	1.648	0.98
480_E	555_D	1.645	0.98
558_E	562_E	1.644	0.98
255_I	267_Y	1.622	0.98
99_I	149_S	1.605	0.98
451_R	482_E	1.604	0.98
316_D	331_K	1.598	0.98
392_R	395_S	1.595	0.98
141_N	145_E	1.594	0.98
105_N	391_G	1.587	0.98
121_L	394_K	1.574	0.98
325_F	337_L	1.564	0.98
102_D	145_E	1.556	0.98
99_I	102_D	1.535	0.97
473_F	550_S	1.510	0.97
332_M	340_K	1.508	0.97
37_Y	144_R	1.503	0.97
167_C	232_V	1.499	0.97
403_N	426_Q	1.484	0.97
271_V	337_L	1.476	0.97
175_F	297_D	1.471	0.97
37_Y	141_N	1.466	0.97
373_K	423_D	1.461	0.97
103_I	142_L	1.461	0.97
105_N	394_K	1.457	0.97
249_Q	270_Y	1.453	0.96
121_L	131_F	1.451	0.96
508_H	526_G	1.449	0.96
255_I	300_L	1.441	0.96
271_V	341_V	1.439	0.96
484_R	558_E	1.426	0.96
402_D	407_L	1.425	0.96
342_R	348_Q	1.416	0.96
291_I	341_V	1.413	0.96
400_I	430_I	1.382	0.95
165_I	413_P	1.376	0.95
342_R	346_G	1.372	0.95
428_E	431_D	1.358	0.95
355_V	358_T	1.338	0.94
269_I	303_V	1.333	0.94
86_I	92_I	1.332	0.94
527_G	579_R	1.324	0.94
491_V	561_F	1.323	0.94
232_V	245_C	1.319	0.94
293_T	297_D	1.315	0.94
404_F	433_I	1.314	0.94
567_N	581_L	1.314	0.94
333_G	336_W	1.306	0.94
557_T	561_F	1.300	0.93
329_V	332_M	1.300	0.93
309_T	344_H	1.298	0.93
62_Y	226_K	1.295	0.93
103_I	145_E	1.292	0.93
469_D	472_R	1.283	0.93
179_S	183_K	1.272	0.93
291_I	334_L	1.269	0.93
292_G	342_R	1.269	0.93
373_K	424_Q	1.259	0.92
306_A	310_I	1.257	0.92
144_R	148_E	1.256	0.92
568_K	580_L	1.253	0.92
264_V	267_Y	1.249	0.92
131_F	142_L	1.247	0.92
397_I	409_F	1.232	0.92
181_A	229_I	1.232	0.92
406_N	421_E	1.230	0.91
97_W	394_K	1.229	0.91
169_L	375_A	1.227	0.91
291_I	338_R	1.226	0.91
270_Y	288_G	1.224	0.91
524_I	560_L	1.215	0.91
267_Y	300_L	1.208	0.91
97_W	409_F	1.206	0.91
138_D	141_N	1.206	0.91
169_L	377_G	1.206	0.91
103_I	151_F	1.201	0.90
305_D	309_T	1.200	0.90
187_Y	305_D	1.194	0.90
141_N	144_R	1.194	0.90
552_R	555_D	1.190	0.90
313_E	344_H	1.188	0.90
102_D	105_N	1.187	0.90
259_I	262_E	1.176	0.89
373_K	421_E	1.174	0.89
400_I	404_F	1.172	0.89
157_C	326_K	1.166	0.89
172_Y	421_E	1.165	0.89
299_E	350_G	1.160	0.89
228_A	248_V	1.147	0.88
523_K	541_N	1.146	0.88
381_E	384_R	1.141	0.88
94_S	401_A	1.137	0.88
568_K	572_E	1.136	0.88
165_I	251_N	1.132	0.88
524_I	544_Y	1.122	0.87
476_S	479_D	1.119	0.87
101_D	395_S	1.116	0.87
62_Y	157_C	1.109	0.87
433_I	436_E	1.107	0.86
269_I	307_I	1.099	0.86
480_E	558_E	1.094	0.86
105_N	119_P	1.090	0.86
366_W	376_Y	1.087	0.85
248_V	256_V	1.085	0.85
448_S	482_E	1.085	0.85
289_L	334_L	1.082	0.85
143_I	153_T	1.078	0.85
168_P	377_G	1.078	0.85
527_G	533_E	1.077	0.85
169_L	367_I	1.076	0.85
361_D	427_K	1.074	0.85
289_L	330_Y	1.074	0.85
371_D	421_E	1.074	0.85
123_L	380_V	1.071	0.85
175_F	265_I	1.071	0.85
484_R	489_I	1.070	0.84
480_E	554_A	1.067	0.84
527_G	534_P	1.060	0.84
378_I	397_I	1.057	0.84
329_V	334_L	1.057	0.84
433_I	437_F	1.053	0.84
532_G	573_D	1.043	0.83
134_V	142_L	1.042	0.83
399_Y	403_N	1.039	0.83
563_L	577_V	1.037	0.83
104_S	131_F	1.030	0.82
332_M	337_L	1.027	0.82
260_E	265_I	1.027	0.82
165_I	228_A	1.025	0.82
142_L	150_G	1.015	0.81
522_L	553_L	1.013	0.81
84_L	151_F	1.012	0.81
411_I	417_L	1.005	0.81
432_G	436_E	1.005	0.81
427_K	431_D	1.003	0.80
374_W	427_K	1.000	0.80
82_V	142_L	0.998	0.80
529_G	533_E	0.998	0.80
211_R	214_F	0.997	0.80
473_F	495_L	0.988	0.79
429_K	433_I	0.988	0.79
561_F	564_Y	0.987	0.79
509_P	575_S	0.987	0.79
501_Q	505_P	0.986	0.79
334_L	338_R	0.983	0.79
30_T	150_G	0.980	0.79
425_P	432_G	0.980	0.79
256_V	268_Q	0.973	0.78
226_K	274_S	0.973	0.78
290_P	293_T	0.968	0.78
101_D	394_K	0.963	0.78
180_L	300_L	0.955	0.77
22_A	51_E	0.953	0.77
293_T	296_N	0.952	0.77
296_N	350_G	0.951	0.77
563_L	581_L	0.948	0.77
40_F	80_Y	0.947	0.76
134_V	139_L	0.946	0.76
63_I	80_Y	0.937	0.76
479_D	483_R	0.935	0.76
37_Y	41_H	0.934	0.75
406_N	426_Q	0.931	0.75
431_D	435_R	0.931	0.75
158_G	274_S	0.931	0.75
562_E	566_K	0.930	0.75
491_V	510_I	0.926	0.75
345_S	349_L	0.922	0.74
36_I	139_L	0.922	0.74
414_N	507_L	0.920	0.74
395_S	399_Y	0.920	0.74
577_V	581_L	0.920	0.74
376_Y	422_I	0.918	0.74
430_I	433_I	0.917	0.74
86_I	128_A	0.916	0.74
501_Q	506_A	0.915	0.74
123_L	129_I	0.914	0.74
542_S	579_R	0.913	0.74
314_W	343_E	0.912	0.74
397_I	419_I	0.910	0.74
366_W	427_K	0.909	0.73
376_Y	427_K	0.908	0.73
512_W	522_L	0.906	0.73
465_L	500_A	0.905	0.73
512_W	557_T	0.898	0.73
382_N	455_T	0.896	0.72
523_K	543_I	0.896	0.72
316_D	319_N	0.893	0.72
550_S	554_A	0.893	0.72
177_A	229_I	0.886	0.71
39_S	52_V	0.881	0.71
291_I	349_L	0.878	0.71
551_N	558_E	0.877	0.71
169_L	418_L	0.873	0.70
89_G	163_N	0.872	0.70
362_L	366_W	0.870	0.70
95_K	99_I	0.868	0.70
184_I	255_I	0.866	0.70
492_S	509_P	0.866	0.70
362_L	452_I	0.865	0.70
27_K	219_N	0.865	0.70
404_F	429_K	0.856	0.69
84_L	100_L	0.855	0.69
43_L	80_Y	0.855	0.69
36_I	39_S	0.851	0.68
419_I	430_I	0.849	0.68
172_Y	376_Y	0.848	0.68
121_L	129_I	0.848	0.68
256_V	270_Y	0.848	0.68
477_L	550_S	0.847	0.68
95_K	402_D	0.847	0.68
132_H	226_K	0.847	0.68
295_V	300_L	0.845	0.68
158_G	226_K	0.844	0.68
451_R	493_I	0.840	0.67
290_P	352_I	0.836	0.67
232_V	242_I	0.833	0.67
397_I	437_F	0.829	0.66
351_K	354_K	0.828	0.66
49_E	52_V	0.828	0.66
155_N	160_N	0.827	0.66
582_G	585_K	0.827	0.66
422_I	427_K	0.827	0.66
152_L	185_A	0.822	0.66
349_L	352_I	0.820	0.66
173_W	176_D	0.820	0.66
377_G	412_T	0.820	0.66
399_Y	436_E	0.818	0.65
478_I	482_E	0.817	0.65
495_L	512_W	0.815	0.65
152_L	189_R	0.807	0.64
21_R	24_L	0.807	0.64
368_N	372_N	0.806	0.64
260_E	266_G	0.805	0.64
390_N	393_T	0.803	0.64
105_N	392_R	0.803	0.64
101_D	398_R	0.801	0.64
54_L	320_R	0.798	0.63
85_P	189_R	0.796	0.63
250_S	535_L	0.794	0.63
480_E	550_S	0.793	0.63
434_L	439_Y	0.791	0.63
487_K	565_E	0.790	0.63
61_I	82_V	0.790	0.63
231_G	257_P	0.789	0.63
259_I	263_K	0.788	0.62
314_W	332_M	0.788	0.62
396_M	399_Y	0.788	0.62
271_V	334_L	0.787	0.62
307_I	337_L	0.785	0.62
367_I	377_G	0.785	0.62
396_M	439_Y	0.785	0.62
154_V	190_L	0.783	0.62
254_G	288_G	0.781	0.62
259_I	265_I	0.779	0.62
267_Y	297_D	0.777	0.61
48_L	80_Y	0.777	0.61
515_S	543_I	0.773	0.61
120_S	462_T	0.773	0.61
472_R	475_P	0.772	0.61
569_D	576_L	0.771	0.61
244_N	248_V	0.770	0.61
385_L	397_I	0.768	0.60
335_E	567_N	0.767	0.60
249_Q	290_P	0.767	0.60
359_H	363_H	0.766	0.60
510_I	557_T	0.766	0.60
22_A	25_K	0.763	0.60
135_K	142_L	0.762	0.60
36_I	40_F	0.760	0.60
62_Y	274_S	0.757	0.59
468_T	520_Y	0.756	0.59
157_C	465_L	0.754	0.59
93_S	96_Q	0.754	0.59
524_I	578_F	0.752	0.59
258_L	294_V	0.750	0.59
187_Y	301_I	0.749	0.58
311_Q	328_V	0.748	0.58
41_H	45_R	0.745	0.58
462_T	470_S	0.741	0.58
253_I	301_I	0.740	0.58
163_N	408_M	0.738	0.57
262_E	265_I	0.737	0.57
250_S	275_M	0.736	0.57
95_K	149_S	0.735	0.57
119_P	391_G	0.734	0.57
157_C	226_K	0.733	0.57
269_I	333_G	0.733	0.57
166_A	229_I	0.731	0.57
91_P	408_M	0.730	0.57
395_S	398_R	0.729	0.56
84_L	104_S	0.729	0.56
52_V	55_I	0.729	0.56
505_P	511_S	0.726	0.56
119_P	520_Y	0.723	0.56
307_I	325_F	0.721	0.56
40_F	140_P	0.721	0.56
159_D	320_R	0.721	0.56
534_P	576_L	0.718	0.55
339_E	425_P	0.717	0.55
560_L	583_N	0.717	0.55
26_T	29_L	0.714	0.55
366_W	431_D	0.714	0.55
336_W	341_V	0.712	0.55
297_D	349_L	0.706	0.54
295_V	524_I	0.706	0.54
91_P	421_E	0.705	0.54
519_L	549_P	0.705	0.54
166_A	177_A	0.703	0.54
493_I	562_E	0.701	0.54
342_R	349_L	0.701	0.54
258_L	268_Q	0.700	0.53
106_K	138_D	0.698	0.53
419_I	570_I	0.698	0.53
139_L	320_R	0.698	0.53
95_K	148_E	0.698	0.53
107_Y	510_I	0.698	0.53
318_K	331_K	0.697	0.53
56_A	470_S	0.695	0.53
396_M	433_I	0.695	0.53
166_A	181_A	0.694	0.53
250_S	287_L	0.689	0.52
132_H	274_S	0.689	0.52
80_Y	499_V	0.688	0.52
399_Y	404_F	0.686	0.52
532_G	576_L	0.685	0.52
517_Y	535_L	0.685	0.52
94_S	419_I	0.685	0.52
384_R	469_D	0.683	0.52
134_V	153_T	0.681	0.51
271_V	291_I	0.680	0.51
229_I	322_W	0.680	0.51
32_D	147_A	0.680	0.51
460_F	469_D	0.679	0.51
62_Y	132_H	0.678	0.51
50_K	53_S	0.677	0.51
164_T	304_L	0.677	0.51
84_L	128_A	0.677	0.51
579_R	584_K	0.676	0.51
174_V	257_P	0.675	0.51
132_H	157_C	0.675	0.51
128_A	189_R	0.673	0.51
64_E	465_L	0.673	0.51
367_I	419_I	0.671	0.50
532_G	579_R	0.670	0.50
145_E	148_E	0.670	0.50
168_P	412_T	0.670	0.50
405_D	422_I	0.670	0.50
408_M	420_T	0.669	0.50
92_I	151_F	0.669	0.50
325_F	341_V	0.669	0.50
64_E	226_K	0.669	0.50
19_E	36_I	0.668	0.50
106_K	141_N	0.667	0.50
132_H	158_G	0.667	0.50
91_P	420_T	0.664	0.50
27_K	214_F	0.663	0.50
473_F	520_Y	0.661	0.49
329_V	337_L	0.660	0.49
40_F	139_L	0.660	0.49
364_L	490_P	0.659	0.49
36_I	85_P	0.656	0.49
89_G	96_Q	0.656	0.49
264_V	298_S	0.654	0.49
255_I	294_V	0.654	0.49
124_T	469_D	0.654	0.49
99_I	106_K	0.653	0.48
38_S	41_H	0.653	0.48
135_K	307_I	0.652	0.48
303_V	345_S	0.652	0.48
178_N	182_R	0.651	0.48
167_C	363_H	0.651	0.48
319_N	322_W	0.650	0.48
175_F	257_P	0.649	0.48
19_E	22_A	0.648	0.48
265_I	353_V	0.648	0.48
100_L	212_E	0.647	0.48
408_M	422_I	0.647	0.48
401_A	407_L	0.647	0.48
180_L	183_K	0.646	0.48
251_N	470_S	0.643	0.47
271_V	307_I	0.641	0.47
63_I	462_T	0.639	0.47
76_K	467_F	0.639	0.47
64_E	274_S	0.639	0.47
267_Y	419_I	0.638	0.47
62_Y	158_G	0.638	0.47
214_F	309_T	0.636	0.47
40_F	43_L	0.635	0.47
227_I	304_L	0.635	0.47
451_R	479_D	0.635	0.47
245_C	363_H	0.634	0.46
338_R	342_R	0.634	0.46
64_E	158_G	0.634	0.46
548_V	553_L	0.633	0.46
393_T	438_N	0.633	0.46
294_V	303_V	0.633	0.46
258_L	266_G	0.633	0.46
247_E	250_S	0.633	0.46
95_K	407_L	0.631	0.46
228_A	250_S	0.631	0.46
295_V	303_V	0.629	0.46
125_T	163_N	0.629	0.46
123_L	165_I	0.629	0.46
94_S	407_L	0.628	0.46
404_F	426_Q	0.628	0.46
92_I	129_I	0.627	0.46
188_F	301_I	0.625	0.46
257_P	265_I	0.625	0.46
103_I	146_V	0.624	0.45
134_V	410_Y	0.623	0.45
392_R	436_E	0.623	0.45
179_S	182_R	0.622	0.45
155_N	190_L	0.622	0.45
394_K	409_F	0.622	0.45
257_P	267_Y	0.621	0.45
467_F	516_G	0.621	0.45
248_V	290_P	0.619	0.45
482_E	583_N	0.619	0.45
493_I	512_W	0.618	0.45
127_Q	383_G	0.618	0.45
335_E	339_E	0.618	0.45
275_M	505_P	0.618	0.45
168_P	413_P	0.618	0.45
87_P	163_N	0.618	0.45
28_G	190_L	0.618	0.45
376_Y	434_L	0.618	0.45
522_L	556_V	0.617	0.45
146_V	149_S	0.616	0.45
271_V	329_V	0.611	0.44
133_H	214_F	0.611	0.44
28_G	372_N	0.609	0.44
172_Y	375_A	0.608	0.44
232_V	366_W	0.607	0.44
346_G	350_G	0.606	0.44
97_W	417_L	0.606	0.44
314_W	336_W	0.606	0.44
16_Y	318_K	0.605	0.43
507_L	526_G	0.605	0.43
369_L	375_A	0.604	0.43
122_K	461_P	0.603	0.43
20_E	23_K	0.602	0.43
255_I	271_V	0.602	0.43
97_W	385_L	0.599	0.43
352_I	355_V	0.599	0.43
104_S	394_K	0.597	0.43
528_N	573_D	0.596	0.43
399_Y	433_I	0.595	0.42
361_D	419_I	0.595	0.42
378_I	570_I	0.594	0.42
171_K	408_M	0.594	0.42
490_P	493_I	0.593	0.42
98_R	398_R	0.593	0.42
350_G	353_V	0.592	0.42
24_L	219_N	0.591	0.42
16_Y	21_R	0.591	0.42
180_L	229_I	0.590	0.42
491_V	564_Y	0.590	0.42
544_Y	583_N	0.590	0.42
403_N	436_E	0.589	0.42
128_A	165_I	0.589	0.42
349_L	522_L	0.589	0.42
368_N	373_K	0.589	0.42
550_S	553_L	0.588	0.42
39_S	56_A	0.588	0.42
320_R	464_K	0.587	0.42
44_S	137_R	0.587	0.42
161_V	227_I	0.587	0.42
517_Y	549_P	0.587	0.42
334_L	339_E	0.586	0.41
403_N	425_P	0.586	0.41
370_G	404_F	0.585	0.41
166_A	412_T	0.583	0.41
263_K	296_N	0.583	0.41
404_F	419_I	0.582	0.41
17_S	318_K	0.582	0.41
248_V	288_G	0.582	0.41
214_F	305_D	0.582	0.41
249_Q	256_V	0.582	0.41
230_A	242_I	0.582	0.41
517_Y	560_L	0.581	0.41
271_V	338_R	0.580	0.41
102_D	107_Y	0.579	0.41
172_Y	176_D	0.579	0.41
368_N	403_N	0.577	0.41
406_N	419_I	0.577	0.41
119_P	403_N	0.576	0.40
188_F	227_I	0.575	0.40
425_P	566_K	0.574	0.40
310_I	344_H	0.574	0.40
107_Y	144_R	0.573	0.40
542_S	582_G	0.572	0.40
310_I	477_L	0.571	0.40
39_S	49_E	0.571	0.40
393_T	439_Y	0.571	0.40
30_T	148_E	0.570	0.40
82_V	136_K	0.568	0.40
524_I	554_A	0.568	0.40
147_A	153_T	0.568	0.40
22_A	417_L	0.568	0.40
376_Y	409_F	0.568	0.40
333_G	338_R	0.566	0.39
18_E	53_S	0.566	0.39
349_L	362_L	0.566	0.39
296_N	347_I	0.566	0.39
86_I	189_R	0.565	0.39
343_E	368_N	0.564	0.39
372_N	423_D	0.564	0.39
382_N	475_P	0.564	0.39
285_S	327_Y	0.563	0.39
346_G	355_V	0.563	0.39
23_K	159_D	0.563	0.39
470_S	578_F	0.562	0.39
458_V	471_E	0.562	0.39
27_K	211_R	0.561	0.39
326_K	465_L	0.560	0.39
274_S	326_K	0.560	0.39
541_N	545_L	0.559	0.39
230_A	256_V	0.558	0.39
86_I	405_D	0.558	0.39
95_K	549_P	0.557	0.39
64_E	132_H	0.556	0.38
174_V	242_I	0.556	0.38
82_V	143_I	0.556	0.38
407_L	430_I	0.556	0.38
410_Y	439_Y	0.556	0.38
381_E	478_I	0.554	0.38
19_E	56_A	0.554	0.38
381_E	475_P	0.554	0.38
409_F	584_K	0.554	0.38
89_G	164_T	0.553	0.38
256_V	290_P	0.552	0.38
21_R	511_S	0.551	0.38
353_V	576_L	0.551	0.38
181_A	304_L	0.550	0.38
253_I	310_I	0.549	0.38
559_A	563_L	0.549	0.38
578_F	583_N	0.548	0.38
473_F	476_S	0.548	0.38
426_Q	560_L	0.548	0.38
401_A	409_F	0.548	0.38
268_Q	292_G	0.548	0.38
291_I	491_V	0.547	0.38
257_P	268_Q	0.546	0.37
505_P	541_N	0.545	0.37
18_E	51_E	0.545	0.37
367_I	418_L	0.545	0.37
53_S	57_K	0.545	0.37
384_R	478_I	0.544	0.37
17_S	511_S	0.544	0.37
184_I	354_K	0.543	0.37
169_L	412_T	0.543	0.37
503_S	506_A	0.543	0.37
359_H	446_P	0.543	0.37
104_S	304_L	0.542	0.37
481_L	554_A	0.541	0.37
248_V	557_T	0.541	0.37
18_E	22_A	0.541	0.37
175_F	367_I	0.539	0.37
164_T	333_G	0.539	0.37
183_K	187_Y	0.539	0.37
230_A	248_V	0.539	0.37
185_A	189_R	0.538	0.37
219_N	493_I	0.538	0.37
307_I	341_V	0.537	0.37
422_I	563_L	0.537	0.37
298_S	343_E	0.536	0.36
339_E	342_R	0.534	0.36
432_G	437_F	0.533	0.36
363_H	377_G	0.533	0.36
455_T	494_G	0.532	0.36
243_D	529_G	0.531	0.36
30_T	212_E	0.531	0.36
48_L	63_I	0.531	0.36
143_I	147_A	0.531	0.36
322_W	511_S	0.531	0.36
473_F	518_E	0.531	0.36
267_Y	542_S	0.531	0.36
61_I	143_I	0.531	0.36
16_Y	219_N	0.530	0.36
454_S	493_I	0.529	0.36
88_G	166_A	0.528	0.36
341_V	349_L	0.527	0.36
118_S	133_H	0.526	0.36
129_I	394_K	0.526	0.36
563_L	568_K	0.526	0.36
186_N	212_E	0.526	0.36
269_I	295_V	0.526	0.36
61_I	142_L	0.525	0.35
393_T	437_F	0.525	0.35
104_S	314_W	0.525	0.35
87_P	272_G	0.524	0.35
16_Y	24_L	0.524	0.35
381_E	479_D	0.523	0.35
369_L	373_K	0.522	0.35
367_I	411_I	0.522	0.35
492_S	528_N	0.522	0.35
474_L	495_L	0.522	0.35
261_D	296_N	0.521	0.35
27_K	30_T	0.521	0.35
39_S	42_D	0.520	0.35
169_L	369_L	0.520	0.35
231_G	242_I	0.519	0.35
469_D	501_Q	0.519	0.35
96_Q	163_N	0.519	0.35
157_C	504_R	0.518	0.35
84_L	129_I	0.518	0.35
146_V	153_T	0.517	0.35
219_N	331_K	0.517	0.35
264_V	296_N	0.517	0.35
322_W	373_K	0.516	0.35
310_I	342_R	0.516	0.35
242_I	245_C	0.516	0.35
176_D	263_K	0.516	0.35
492_S	507_L	0.515	0.34
479_D	482_E	0.514	0.34
268_Q	293_T	0.513	0.34
158_G	285_S	0.513	0.34
78_W	495_L	0.513	0.34
26_T	144_R	0.513	0.34
380_V	416_H	0.513	0.34
573_D	584_K	0.509	0.34
404_F	483_R	0.509	0.34
325_F	328_V	0.509	0.34
311_Q	315_G	0.508	0.34
456_A	469_D	0.508	0.34
491_V	509_P	0.507	0.34
183_K	301_I	0.506	0.34
86_I	96_Q	0.506	0.34
161_V	188_F	0.506	0.34
564_Y	579_R	0.506	0.34
248_V	270_Y	0.505	0.34
179_S	296_N	0.505	0.34
581_L	584_K	0.504	0.33
451_R	481_L	0.504	0.33
291_I	314_W	0.504	0.33
473_F	553_L	0.504	0.33
188_F	304_L	0.503	0.33
475_P	479_D	0.503	0.33
36_I	146_V	0.503	0.33
125_T	276_G	0.503	0.33
334_L	392_R	0.502	0.33
84_L	321_H	0.502	0.33
16_Y	419_I	0.502	0.33
527_G	575_S	0.501	0.33
94_S	98_R	0.500	0.33

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g38A	1	0.7	100	0.344	Contact Map
1zj8A	1	0.8206	100	0.378	Contact Map
3b0gA	1	0.7952	100	0.427	Contact Map
2akjA	1	0.7952	100	0.431	Contact Map
3mm5A	1	0.5127	100	0.778	Contact Map
3or1A	2	0.5095	100	0.786	Contact Map
3or1B	2	0.4794	100	0.791	Contact Map
3mm5B	2	0.4365	100	0.812	Contact Map
3noyA	2	0.5349	98.8	0.946	Contact Map
4s39A	2	0.5651	91.4	0.975	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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