GREMLIN Database
Q97UT0 - Uncharacterized protein
UniProt: Q97UT0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 284 (234)
Sequences: 12465 (8884)
Seq/√Len: 580.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
245_S249_A3.6371.00
226_E230_R3.4831.00
84_G138_F3.4211.00
17_I218_M3.3921.00
227_D230_R3.0841.00
67_S167_E3.0071.00
9_S207_A2.9081.00
91_I142_V2.8791.00
80_G134_Y2.5871.00
11_I33_L2.4631.00
217_F221_V2.4381.00
67_S70_S2.3931.00
13_F211_G2.3811.00
224_H227_D2.3061.00
213_L217_F2.2361.00
69_R72_V2.2241.00
164_T167_E2.2161.00
114_L118_A2.0871.00
71_L174_V2.0521.00
106_Y243_G2.0151.00
152_P156_L2.0081.00
244_L248_L1.9871.00
53_F205_S1.9661.00
68_I72_V1.9101.00
75_I178_V1.9011.00
69_R73_F1.8231.00
63_F68_I1.8171.00
113_I240_S1.7971.00
57_T209_I1.7771.00
113_I243_G1.7491.00
48_N183_T1.7381.00
110_I243_G1.6711.00
57_T213_L1.6551.00
81_V179_E1.6521.00
12_I204_T1.6411.00
199_Y203_V1.6341.00
90_Y95_S1.6281.00
46_I201_A1.6011.00
49_F201_A1.5831.00
70_S163_L1.5831.00
217_F220_N1.5721.00
113_I233_M1.5391.00
107_S111_P1.5341.00
89_A186_A1.5171.00
75_I79_P1.5101.00
207_A211_G1.5081.00
39_T42_Q1.4871.00
86_I186_A1.4791.00
15_A29_T1.4781.00
230_R234_S1.4761.00
131_K135_L1.4661.00
140_V153_P1.4661.00
13_F210_A1.4621.00
84_G88_G1.4561.00
72_V79_P1.4511.00
61_L216_I1.4481.00
72_V75_I1.4411.00
87_V138_F1.4301.00
106_Y247_N1.4241.00
80_G137_T1.4201.00
202_T206_P1.4041.00
65_N220_N1.4031.00
60_I63_F1.3961.00
234_S241_G1.3821.00
131_K134_Y1.3811.00
6_I10_V1.3611.00
80_G84_G1.3581.00
42_Q45_P1.3521.00
58_N173_A1.3481.00
17_I214_I1.3401.00
71_L171_A1.3381.00
117_A233_M1.3131.00
99_T103_V1.3091.00
79_P83_I1.3091.00
90_Y93_K1.2981.00
12_I207_A1.2741.00
62_N219_G1.2561.00
82_L182_S1.2531.00
100_L103_V1.2341.00
227_D231_L1.2241.00
108_I147_T1.2231.00
100_L104_I1.2221.00
240_S244_L1.2191.00
136_V157_I1.2111.00
154_L175_L1.2081.00
86_I90_Y1.2051.00
129_W132_I1.2021.00
138_F142_V1.2001.00
56_L60_I1.1841.00
245_S248_L1.1781.00
152_P155_A1.1771.00
56_L177_T1.1761.00
59_V174_V1.1711.00
5_L203_V1.1541.00
110_I240_S1.1471.00
97_N100_L1.1411.00
186_A190_L1.1281.00
185_G189_T1.1091.00
118_A121_R1.1041.00
206_P210_A1.0961.00
58_N212_M1.0951.00
209_I213_L1.0831.00
10_V14_I1.0821.00
165_K225_K1.0821.00
13_F214_I1.0821.00
98_E102_K1.0801.00
52_M181_V1.0751.00
211_G214_I1.0721.00
181_V185_G1.0691.00
66_Y171_A1.0621.00
62_N170_F1.0591.00
121_R124_I1.0591.00
111_P115_L1.0571.00
83_I86_I1.0541.00
153_P156_L1.0531.00
87_V90_Y1.0521.00
42_Q194_N1.0461.00
59_V63_F1.0461.00
135_L139_P1.0381.00
73_F79_P1.0371.00
12_I30_A1.0341.00
132_I135_L1.0271.00
8_L204_T1.0251.00
166_Q219_G1.0211.00
85_S183_T1.0101.00
225_K229_R1.0021.00
241_G245_S1.0001.00
211_G215_G0.9961.00
102_K249_A0.9771.00
7_Y10_V0.9761.00
80_G83_I0.9731.00
214_I217_F0.9691.00
68_I71_L0.9591.00
73_F80_G0.9571.00
21_A222_I0.9561.00
194_N199_Y0.9551.00
12_I16_S0.9531.00
103_V107_S0.9521.00
35_L40_N0.9511.00
110_I114_L0.9471.00
114_L240_S0.9451.00
103_V247_N0.9401.00
99_T102_K0.9351.00
144_Y150_S0.9311.00
202_T205_S0.9171.00
57_T212_M0.9101.00
89_A182_S0.9071.00
188_L198_I0.9061.00
31_T47_L0.9021.00
13_F207_A0.9001.00
106_Y110_I0.8981.00
44_S187_Y0.8971.00
9_S203_V0.8931.00
71_L175_L0.8831.00
91_I95_S0.8801.00
59_V177_T0.8761.00
73_F130_K0.8741.00
210_A213_L0.8681.00
62_N216_I0.8651.00
133_G161_Q0.8641.00
194_N200_Y0.8621.00
87_V142_V0.8601.00
116_Q233_M0.8561.00
176_R179_E0.8541.00
165_K228_F0.8531.00
52_M184_F0.8531.00
40_N105_V0.8531.00
103_V106_Y0.8421.00
167_E170_F0.8391.00
60_I64_K0.8371.00
89_A183_T0.8331.00
73_F134_Y0.8301.00
74_T175_L0.8281.00
119_G122_K0.8231.00
34_L204_T0.8161.00
89_A187_Y0.8161.00
16_S20_G0.8161.00
63_F66_Y0.8101.00
203_V206_P0.8081.00
224_H230_R0.8041.00
87_V91_I0.8011.00
116_Q232_V0.8011.00
51_E180_S0.8011.00
74_T158_I0.7831.00
92_L187_Y0.7831.00
81_V175_L0.7811.00
15_A30_A0.7801.00
185_G188_L0.7721.00
19_T27_S0.7721.00
38_Y200_Y0.7711.00
88_G142_V0.7691.00
96_A146_V0.7631.00
83_I87_V0.7601.00
61_L65_N0.7551.00
140_V154_L0.7531.00
22_F231_L0.7501.00
144_Y179_E0.7481.00
229_R233_M0.7451.00
30_A204_T0.7451.00
35_L43_I0.7431.00
118_A122_K0.7411.00
184_F201_A0.7401.00
121_R125_G0.7381.00
9_S206_P0.7361.00
61_L64_K0.7321.00
42_Q46_I0.7301.00
159_N168_F0.7291.00
193_F198_I0.7231.00
50_I208_V0.7211.00
38_Y42_Q0.7181.00
85_S182_S0.7181.00
51_E150_S0.7161.00
7_Y37_R0.7151.00
243_G247_N0.7131.00
96_A100_L0.7121.00
8_L200_Y0.7081.00
31_T43_I0.7071.00
113_I117_A0.7031.00
148_T172_I0.7021.00
218_M221_V0.7001.00
198_I202_T0.7001.00
84_G142_V0.6961.00
231_L234_S0.6931.00
47_L51_E0.6931.00
156_L160_N0.6881.00
28_S109_L0.6871.00
137_T154_L0.6851.00
163_L167_E0.6851.00
177_T181_V0.6831.00
67_S72_V0.6831.00
57_T61_L0.6821.00
8_L203_V0.6811.00
93_K190_L0.6801.00
13_F17_I0.6781.00
169_K219_G0.6771.00
48_N148_T0.6751.00
90_Y190_L0.6731.00
172_I176_R0.6711.00
40_N101_F0.6711.00
9_S13_F0.6681.00
149_I152_P0.6661.00
174_V178_V0.6651.00
216_I220_N0.6641.00
201_A205_S0.6641.00
17_I211_G0.6641.00
85_S89_A0.6601.00
130_K134_Y0.6581.00
165_K169_K0.6561.00
226_E229_R0.6551.00
115_L119_G0.6551.00
36_I245_S0.6501.00
45_P193_F0.6501.00
20_G216_I0.6481.00
20_G212_M0.6471.00
61_L213_L0.6441.00
65_N217_F0.6421.00
222_I227_D0.6411.00
106_Y246_F0.6371.00
233_M240_S0.6371.00
61_L217_F0.6341.00
111_P114_L0.6331.00
55_N150_S0.6321.00
110_I113_I0.6271.00
66_Y71_L0.6251.00
137_T141_G0.6241.00
119_G229_R0.6201.00
123_E126_L0.6191.00
231_L235_F0.6181.00
157_I161_Q0.6171.00
155_A168_F0.6131.00
66_Y174_V0.6121.00
33_L37_R0.6111.00
19_T176_R0.6111.00
55_N177_T0.6101.00
16_S26_F0.6101.00
30_A47_L0.6091.00
154_L158_I0.6081.00
55_N180_S0.6061.00
210_A214_I0.6031.00
208_V212_M0.5961.00
140_V143_L0.5931.00
112_L152_P0.5911.00
140_V150_S0.5911.00
199_Y202_T0.5901.00
88_G92_L0.5851.00
132_I136_V0.5821.00
50_I204_T0.5801.00
110_I244_L0.5791.00
67_S171_A0.5781.00
31_T44_S0.5761.00
150_S154_L0.5741.00
230_R233_M0.5741.00
26_F47_L0.5741.00
194_N198_I0.5731.00
144_Y149_I0.5701.00
244_L247_N0.5661.00
30_A34_L0.5661.00
59_V68_I0.5650.99
56_L59_V0.5640.99
24_Y232_V0.5630.99
203_V207_A0.5630.99
232_V239_I0.5620.99
54_Q208_V0.5610.99
158_I163_L0.5570.99
52_M56_L0.5560.99
41_K44_S0.5540.99
113_I116_Q0.5540.99
19_T51_E0.5530.99
212_M216_I0.5520.99
157_I160_N0.5520.99
214_I218_M0.5510.99
154_L157_I0.5500.99
74_T137_T0.5500.99
51_E144_Y0.5480.99
38_Y43_I0.5460.99
38_Y194_N0.5460.99
71_L75_I0.5450.99
109_L239_I0.5440.99
55_N148_T0.5440.99
224_H228_F0.5430.99
40_N44_S0.5410.99
21_A218_M0.5400.99
20_G58_N0.5390.99
183_T186_A0.5370.99
192_I199_Y0.5360.99
199_Y206_P0.5360.99
198_I201_A0.5350.99
53_F56_L0.5350.99
112_L116_Q0.5340.99
152_P158_I0.5320.99
242_Y245_S0.5300.99
48_N184_F0.5290.99
113_I239_I0.5270.99
53_F209_I0.5260.99
41_K92_L0.5220.99
150_S176_R0.5210.99
13_F16_S0.5200.99
55_N176_R0.5200.99
84_G87_V0.5180.99
44_S92_L0.5170.99
7_Y11_I0.5160.99
38_Y46_I0.5160.99
187_Y192_I0.5130.99
54_Q148_T0.5110.99
83_I138_F0.5100.99
16_S208_V0.5060.99
180_S183_T0.5050.99
159_N165_K0.5050.99
21_A215_G0.5030.99
44_S148_T0.5010.99
222_I228_F0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3llqA 3 0.6725 34.7 0.936 Contact Map
2f2bA 4 0.6831 23.4 0.941 Contact Map
3o7qA 1 0.8592 22.8 0.941 Contact Map
2gfpA 2 0.8486 22.5 0.942 Contact Map
4bwzA 2 0.7746 17.5 0.944 Contact Map
1pw4A 1 0.8768 14.8 0.946 Contact Map
4cz8A 2 0.7817 14.3 0.947 Contact Map
3cn5A 3 0.6796 14 0.947 Contact Map
3wdoA 1 0.8556 11 0.949 Contact Map
2cfqA 1 0.4472 10.6 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.