Q97UR7 - SULSO - GREMLIN Contacts

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Q97UR7 - N-methylhydantoinase B (HyuB-3)

UniProt:	Q97UR7	Sequences: MTSWEIIYKASEFIAEEMGVMLKRSAMSPNIRERMDHSCAITDAEGNIIAQAEHIPVHLGSFSIGVKNTLNQIEELEEGDMIVLNDPYTSGTHLNDVMVLAPVYYNGNLMGYVVNKAHQVDVGGPMPGSLNPYATTIYEEGFVIPPVRLMRKGEINNEIINIIKHNFKVPEVSIGDLNAQISANLNGIARIKQMFDKYGYDNVLNAWKTSMEYGKKLALSEISKWGNGIGEDEDYLEIGDELKKIRLKVKVDENGVYANFAGTDTQMEGPLNAVYGVTFSAVSFVIRSLIGKDIPTNEGFYSLIKVDAPKGTIVNPNKPAAVGGGNVETSQRIADVTFKALSHLISVPAAGSGTMMNVMMGGMYKGKYWAYYETIGGGTGARPNKDGVSAVQVNMTNTLNTPIEIAERYYPIMFTIYRIRENSGGVGKYKGGDGIIRAFRVLEKTRLSIIAERFRVAPWGLKGGGNGKPAKVTIIRADGRKEEMPSKFSTILNKGDEIIIETPGGGGYYTPNE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	513 (501)
Sequences:	2237 (1376)
Seq/√Len:	61.5

SULSO - Q97UR7 Q97WV3 Q97XP9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
415_T	440_R	5.701	1.00
255_G	305_K	4.700	1.00
77_E	152_K	4.531	1.00
384_N	429_Y	4.412	1.00
232_D	339_K	4.305	1.00
76_L	82_I	4.188	1.00
227_N	253_E	3.944	1.00
471_K	501_E	3.832	1.00
261_A	307_D	3.795	1.00
257_Y	307_D	3.687	1.00
215_K	302_S	3.670	1.00
257_Y	305_K	3.450	1.00
215_K	219_L	3.314	1.00
103_V	113_V	3.150	1.00
43_D	47_N	3.118	1.00
310_K	317_N	3.108	1.00
78_E	107_G	3.094	1.00
212_E	302_S	2.916	1.00
101_A	184_N	2.884	1.00
135_T	139_E	2.881	1.00
229_I	250_K	2.878	1.00
389_S	433_D	2.820	1.00
83_V	97_V	2.753	1.00
231_E	248_K	2.751	1.00
148_R	151_R	2.665	1.00
262_G	309_P	2.612	1.00
416_I	438_A	2.596	1.00
265_T	309_P	2.505	1.00
386_D	430_K	2.444	1.00
438_A	499_I	2.421	1.00
457_A	469_P	2.370	1.00
77_E	151_R	2.368	1.00
151_R	156_N	2.360	1.00
167_F	170_P	2.356	1.00
350_A	459_W	2.345	1.00
440_R	497_E	2.300	1.00
308_A	315_N	2.288	1.00
263_T	313_I	2.282	1.00
144_I	162_I	2.255	1.00
233_E	244_K	2.251	1.00
190_R	193_Q	2.250	1.00
266_Q	320_A	2.219	1.00
115_N	184_N	2.177	1.00
415_T	438_A	2.171	1.00
275_Y	308_A	2.166	1.00
444_K	494_K	2.155	1.00
413_M	442_L	2.146	1.00
233_E	246_R	2.118	1.00
17_E	190_R	2.080	1.00
219_L	255_G	2.060	1.00
136_T	139_E	2.053	1.00
309_P	315_N	2.050	1.00
247_L	258_A	2.038	1.00
426_V	465_G	2.016	1.00
476_R	482_E	1.993	1.00
223_S	253_E	1.977	1.00
72_Q	161_N	1.947	1.00
436_I	501_E	1.944	1.00
390_A	419_I	1.929	1.00
328_E	354_T	1.917	1.00
244_K	264_D	1.894	1.00
362_G	443_E	1.877	1.00
76_L	112_Y	1.867	1.00
473_T	481_K	1.859	1.00
10_A	197_K	1.854	1.00
195_F	203_V	1.852	1.00
444_K	493_N	1.842	1.00
229_I	248_K	1.824	1.00
286_I	304_I	1.819	1.00
105_Y	196_D	1.806	1.00
83_V	99_V	1.802	1.00
195_F	200_Y	1.799	1.00
382_R	385_K	1.797	1.00
227_N	254_N	1.796	1.00
438_A	497_E	1.792	1.00
379_T	388_V	1.780	1.00
452_E	487_K	1.764	0.99
386_D	429_Y	1.764	0.99
358_V	447_L	1.762	0.99
310_K	315_N	1.760	0.99
108_N	204_L	1.759	0.99
119_Q	180_Q	1.758	0.99
419_I	433_D	1.747	0.99
223_S	254_N	1.745	0.99
426_V	430_K	1.737	0.99
110_M	195_F	1.726	0.99
49_I	207_W	1.726	0.99
476_R	496_D	1.714	0.99
47_N	67_K	1.711	0.99
70_L	112_Y	1.708	0.99
125_P	133_Y	1.705	0.99
150_M	181_I	1.686	0.99
231_E	246_R	1.686	0.99
471_K	483_E	1.684	0.99
474_I	492_L	1.660	0.99
227_N	251_V	1.653	0.99
415_T	497_E	1.639	0.99
31_I	117_A	1.629	0.99
211_M	302_S	1.625	0.99
358_V	498_I	1.624	0.99
234_D	453_R	1.602	0.99
376_G	435_I	1.602	0.99
245_I	336_V	1.585	0.99
420_R	423_S	1.576	0.99
418_R	436_I	1.574	0.99
234_D	336_V	1.568	0.99
225_W	230_G	1.557	0.99
250_K	253_E	1.554	0.99
38_S	58_H	1.548	0.99
493_N	496_D	1.545	0.99
215_K	303_L	1.537	0.99
7_I	206_A	1.537	0.99
403_I	414_F	1.528	0.98
5_E	8_Y	1.526	0.98
422_N	433_D	1.524	0.98
47_N	302_S	1.523	0.98
462_K	508_Y	1.522	0.98
82_I	148_R	1.516	0.98
362_G	369_W	1.514	0.98
101_A	188_I	1.490	0.98
83_V	144_I	1.488	0.98
258_A	304_I	1.485	0.98
357_N	372_Y	1.477	0.98
44_A	204_L	1.463	0.98
258_A	282_V	1.457	0.98
47_N	208_K	1.453	0.98
266_Q	317_N	1.448	0.98
220_S	223_S	1.437	0.98
108_N	200_Y	1.418	0.97
241_E	264_D	1.412	0.97
81_M	101_A	1.409	0.97
309_P	312_T	1.404	0.97
284_F	394_N	1.398	0.97
19_G	54_H	1.397	0.97
475_I	479_G	1.387	0.97
159_I	162_I	1.387	0.97
375_I	500_I	1.384	0.97
125_P	139_E	1.377	0.97
105_Y	109_L	1.375	0.97
420_R	468_K	1.375	0.97
77_E	148_R	1.362	0.97
421_E	433_D	1.361	0.97
285_V	337_T	1.361	0.97
209_T	212_E	1.344	0.96
106_N	196_D	1.337	0.96
88_Y	319_P	1.333	0.96
221_E	224_K	1.332	0.96
47_N	298_E	1.327	0.96
459_W	466_N	1.327	0.96
105_Y	110_M	1.316	0.96
413_M	440_R	1.315	0.96
47_N	211_M	1.313	0.96
83_V	149_L	1.313	0.96
475_I	478_D	1.306	0.96
470_A	503_P	1.305	0.96
143_V	318_K	1.296	0.96
288_S	338_F	1.289	0.96
266_Q	311_G	1.287	0.95
255_G	303_L	1.286	0.95
416_I	436_I	1.282	0.95
275_Y	315_N	1.282	0.95
473_T	499_I	1.276	0.95
10_A	194_M	1.275	0.95
149_L	181_I	1.268	0.95
157_N	161_N	1.268	0.95
230_G	251_V	1.263	0.95
250_K	257_Y	1.263	0.95
131_N	134_A	1.261	0.95
312_T	315_N	1.256	0.95
441_V	445_T	1.255	0.95
97_V	122_V	1.253	0.95
234_D	332_R	1.252	0.95
103_V	188_I	1.249	0.95
474_I	490_T	1.248	0.95
151_R	154_E	1.245	0.95
475_I	499_I	1.245	0.95
265_T	312_T	1.244	0.95
135_T	268_E	1.244	0.95
188_I	192_K	1.238	0.94
236_L	271_L	1.229	0.94
379_T	393_V	1.225	0.94
249_V	258_A	1.223	0.94
73_I	146_P	1.221	0.94
457_A	466_N	1.217	0.94
192_K	196_D	1.199	0.93
478_D	481_K	1.194	0.93
251_V	254_N	1.192	0.93
420_R	501_E	1.191	0.93
335_D	453_R	1.191	0.93
232_D	459_W	1.185	0.93
308_A	314_V	1.180	0.93
200_Y	204_L	1.178	0.93
260_F	282_V	1.169	0.93
477_A	496_D	1.166	0.92
216_K	220_S	1.166	0.92
18_M	187_G	1.153	0.92
474_I	484_M	1.149	0.92
160_I	171_E	1.149	0.92
78_E	192_K	1.144	0.92
142_F	163_I	1.143	0.92
81_M	150_M	1.140	0.92
473_T	501_E	1.138	0.92
424_G	433_D	1.137	0.91
275_Y	279_F	1.133	0.91
97_V	119_Q	1.130	0.91
420_R	436_I	1.127	0.91
105_Y	195_F	1.126	0.91
281_A	334_A	1.126	0.91
70_L	109_L	1.117	0.91
242_L	456_V	1.116	0.91
219_L	303_L	1.109	0.90
431_G	504_G	1.106	0.90
7_I	11_S	1.103	0.90
332_R	452_E	1.102	0.90
279_F	306_V	1.101	0.90
30_N	34_R	1.101	0.90
266_Q	319_P	1.101	0.90
390_A	435_I	1.099	0.90
151_R	158_E	1.096	0.90
475_I	481_K	1.090	0.90
227_N	230_G	1.089	0.90
339_K	459_W	1.083	0.89
422_N	426_V	1.078	0.89
212_E	215_K	1.077	0.89
227_N	252_D	1.071	0.89
216_K	254_N	1.068	0.89
226_G	251_V	1.068	0.89
193_Q	197_K	1.065	0.89
67_K	298_E	1.064	0.88
147_V	159_I	1.062	0.88
105_Y	192_K	1.055	0.88
225_W	251_V	1.053	0.88
314_V	333_I	1.050	0.88
81_M	184_N	1.050	0.88
185_L	189_A	1.046	0.88
115_N	183_A	1.041	0.87
203_V	207_W	1.033	0.87
420_R	434_G	1.033	0.87
138_Y	318_K	1.028	0.87
261_A	309_P	1.025	0.87
222_I	251_V	1.018	0.86
110_M	200_Y	1.018	0.86
222_I	227_N	1.018	0.86
349_A	461_L	1.013	0.86
189_A	193_Q	1.011	0.86
438_A	475_I	1.009	0.86
103_V	191_I	1.008	0.86
194_M	198_Y	1.006	0.86
358_V	439_F	1.005	0.85
370_A	401_T	1.004	0.85
451_A	472_V	0.997	0.85
192_K	195_F	0.996	0.85
208_K	212_E	0.996	0.85
414_F	439_F	0.992	0.85
248_K	262_G	0.986	0.84
270_P	321_A	0.985	0.84
400_N	417_Y	0.983	0.84
260_F	333_I	0.975	0.84
477_A	493_N	0.974	0.84
10_A	14_I	0.973	0.84
428_K	510_T	0.973	0.84
98_M	116_K	0.968	0.83
61_S	92_T	0.967	0.83
156_N	159_I	0.967	0.83
86_D	145_P	0.966	0.83
317_N	320_A	0.963	0.83
441_V	492_L	0.956	0.82
446_R	491_I	0.952	0.82
436_I	499_I	0.951	0.82
81_M	181_I	0.951	0.82
485_P	488_F	0.949	0.82
164_K	174_I	0.946	0.82
45_E	208_K	0.944	0.82
42_T	114_V	0.941	0.81
465_G	511_P	0.930	0.81
235_Y	456_V	0.929	0.81
373_E	437_R	0.926	0.80
215_K	255_G	0.922	0.80
476_R	479_G	0.921	0.80
14_I	194_M	0.919	0.80
219_L	254_N	0.916	0.80
110_M	204_L	0.914	0.80
263_T	309_P	0.911	0.79
282_V	306_V	0.908	0.79
155_I	174_I	0.907	0.79
155_I	160_I	0.905	0.79
41_I	113_V	0.902	0.79
95_N	397_N	0.902	0.79
430_K	433_D	0.895	0.78
475_I	496_D	0.895	0.78
423_S	504_G	0.894	0.78
164_K	171_E	0.893	0.78
20_V	23_K	0.892	0.78
184_N	188_I	0.890	0.78
165_H	168_K	0.883	0.77
263_T	312_T	0.882	0.77
369_W	445_T	0.881	0.77
134_A	321_A	0.877	0.77
335_D	377_G	0.876	0.77
34_R	374_T	0.874	0.76
78_E	188_I	0.857	0.75
263_T	314_V	0.855	0.75
196_D	223_S	0.854	0.75
473_T	483_E	0.850	0.74
235_Y	244_K	0.850	0.74
86_D	146_P	0.849	0.74
222_I	230_G	0.846	0.74
174_I	178_N	0.845	0.74
186_N	190_R	0.843	0.74
83_V	159_I	0.840	0.74
324_G	450_I	0.836	0.73
335_D	353_G	0.833	0.73
238_I	267_M	0.833	0.73
149_L	156_N	0.832	0.73
63_S	298_E	0.831	0.73
352_S	377_G	0.828	0.72
71_N	78_E	0.827	0.72
67_K	71_N	0.827	0.72
100_L	112_Y	0.826	0.72
64_I	279_F	0.824	0.72
69_T	82_I	0.820	0.72
231_E	428_K	0.819	0.72
148_R	156_N	0.819	0.72
238_I	269_G	0.818	0.72
70_L	76_L	0.818	0.72
58_H	61_S	0.815	0.71
229_I	246_R	0.811	0.71
219_L	253_E	0.809	0.71
350_A	353_G	0.807	0.71
219_L	227_N	0.806	0.70
147_V	156_N	0.804	0.70
233_E	241_E	0.800	0.70
212_E	216_K	0.797	0.70
360_M	445_T	0.796	0.69
137_I	319_P	0.787	0.69
267_M	271_L	0.787	0.69
386_D	510_T	0.786	0.68
294_I	300_F	0.784	0.68
109_L	112_Y	0.783	0.68
342_S	462_K	0.783	0.68
447_L	498_I	0.781	0.68
65_G	84_L	0.780	0.68
76_L	109_L	0.780	0.68
361_G	372_Y	0.775	0.67
277_V	326_N	0.774	0.67
383_P	429_Y	0.768	0.67
262_G	265_T	0.767	0.67
316_P	320_A	0.767	0.67
106_N	252_D	0.766	0.66
211_M	298_E	0.765	0.66
347_V	350_A	0.765	0.66
199_G	202_N	0.765	0.66
357_N	361_G	0.764	0.66
86_D	143_V	0.764	0.66
61_S	65_G	0.764	0.66
350_A	466_N	0.763	0.66
223_S	227_N	0.758	0.66
38_S	51_Q	0.758	0.66
78_E	152_K	0.757	0.66
283_S	301_Y	0.751	0.65
64_I	276_G	0.751	0.65
448_S	489_S	0.750	0.65
406_A	414_F	0.749	0.65
214_G	218_A	0.748	0.65
22_L	117_A	0.748	0.65
232_D	336_V	0.745	0.64
476_R	480_R	0.744	0.64
159_I	477_A	0.743	0.64
221_E	225_W	0.743	0.64
211_M	215_K	0.742	0.64
5_E	9_K	0.742	0.64
430_K	507_G	0.740	0.64
278_T	308_A	0.740	0.64
21_M	186_N	0.739	0.64
147_V	162_I	0.738	0.64
23_K	37_H	0.735	0.63
32_R	409_Y	0.734	0.63
185_L	188_I	0.733	0.63
447_L	492_L	0.733	0.63
251_V	256_V	0.731	0.63
186_N	189_A	0.731	0.63
217_L	291_G	0.730	0.63
161_N	164_K	0.724	0.62
377_G	380_G	0.724	0.62
262_G	308_A	0.722	0.62
461_L	508_Y	0.720	0.62
113_V	188_I	0.719	0.62
71_N	106_N	0.718	0.61
453_R	458_P	0.715	0.61
369_W	443_E	0.713	0.61
339_K	350_A	0.713	0.61
24_R	498_I	0.710	0.61
27_M	175_G	0.709	0.60
214_G	297_N	0.709	0.60
99_V	181_I	0.708	0.60
235_Y	455_R	0.708	0.60
144_I	147_V	0.708	0.60
42_T	62_F	0.707	0.60
232_D	340_A	0.706	0.60
438_A	501_E	0.706	0.60
274_V	316_P	0.705	0.60
213_Y	217_L	0.704	0.60
18_M	39_C	0.702	0.60
126_M	133_Y	0.700	0.60
440_R	495_G	0.700	0.60
106_N	201_D	0.699	0.59
99_V	184_N	0.696	0.59
229_I	252_D	0.695	0.59
57_V	281_A	0.695	0.59
353_G	458_P	0.695	0.59
144_I	149_L	0.695	0.59
417_Y	437_R	0.693	0.59
371_Y	439_F	0.693	0.59
73_I	82_I	0.689	0.58
30_N	374_T	0.688	0.58
383_P	508_Y	0.688	0.58
236_L	452_E	0.687	0.58
258_A	286_I	0.687	0.58
156_N	161_N	0.687	0.58
65_G	274_V	0.683	0.58
164_K	170_P	0.681	0.57
71_N	333_I	0.680	0.57
255_G	302_S	0.679	0.57
90_S	95_N	0.679	0.57
287_R	292_K	0.678	0.57
273_A	325_G	0.678	0.57
90_S	276_G	0.678	0.57
252_D	257_Y	0.677	0.57
384_N	428_K	0.677	0.57
155_I	178_N	0.676	0.57
3_S	202_N	0.674	0.57
355_M	395_M	0.673	0.57
167_F	173_S	0.672	0.56
94_L	141_G	0.671	0.56
164_K	167_F	0.669	0.56
152_K	317_N	0.669	0.56
38_S	59_L	0.668	0.56
71_N	161_N	0.668	0.56
271_L	321_A	0.665	0.56
380_G	505_G	0.664	0.56
456_V	469_P	0.664	0.56
57_V	395_M	0.664	0.56
150_M	155_I	0.663	0.55
54_H	58_H	0.662	0.55
80_D	148_R	0.662	0.55
6_I	198_Y	0.661	0.55
380_G	431_G	0.660	0.55
73_I	151_R	0.660	0.55
218_A	274_V	0.658	0.55
69_T	100_L	0.656	0.55
224_K	227_N	0.656	0.55
187_G	337_T	0.656	0.55
336_V	453_R	0.656	0.55
332_R	458_P	0.654	0.54
55_I	398_T	0.652	0.54
221_E	290_I	0.652	0.54
3_S	198_Y	0.650	0.54
154_E	455_R	0.648	0.54
101_A	115_N	0.647	0.54
80_D	152_K	0.647	0.54
115_N	180_Q	0.646	0.53
474_I	498_I	0.645	0.53
201_D	491_I	0.645	0.53
103_V	187_G	0.645	0.53
286_I	341_L	0.645	0.53
23_K	35_M	0.643	0.53
103_V	111_G	0.643	0.53
362_G	368_Y	0.642	0.53
34_R	392_Q	0.642	0.53
277_V	325_G	0.641	0.53
21_M	25_S	0.637	0.52
46_G	70_L	0.637	0.52
26_A	335_D	0.636	0.52
119_Q	397_N	0.635	0.52
34_R	398_T	0.632	0.52
349_A	380_G	0.631	0.52
68_N	71_N	0.631	0.52
234_D	459_W	0.630	0.52
77_E	107_G	0.628	0.51
19_G	37_H	0.628	0.51
483_E	501_E	0.627	0.51
41_I	191_I	0.627	0.51
465_G	507_G	0.626	0.51
460_G	466_N	0.625	0.51
182_S	297_N	0.625	0.51
354_T	503_P	0.625	0.51
477_A	481_K	0.625	0.51
277_V	330_S	0.624	0.51
108_N	466_N	0.623	0.51
452_E	486_S	0.622	0.51
75_E	148_R	0.622	0.51
428_K	462_K	0.622	0.51
88_Y	92_T	0.621	0.51
475_I	497_E	0.619	0.50
460_G	464_G	0.619	0.50
429_Y	497_E	0.619	0.50
473_T	492_L	0.618	0.50
113_V	187_G	0.618	0.50
146_P	199_G	0.617	0.50
374_T	398_T	0.614	0.50
154_E	252_D	0.614	0.50
59_L	397_N	0.614	0.50
368_Y	443_E	0.613	0.50
216_K	223_S	0.613	0.50
105_Y	200_Y	0.613	0.50
21_M	101_A	0.612	0.50
40_A	54_H	0.611	0.49
25_S	37_H	0.611	0.49
162_I	166_N	0.610	0.49
44_A	109_L	0.610	0.49
246_R	261_A	0.610	0.49
248_K	261_A	0.609	0.49
152_K	189_A	0.608	0.49
104_Y	109_L	0.607	0.49
474_I	481_K	0.607	0.49
42_T	48_I	0.606	0.49
138_Y	167_F	0.605	0.49
240_D	268_E	0.604	0.49
298_E	302_S	0.603	0.49
161_N	310_K	0.603	0.49
100_L	114_V	0.602	0.48
55_I	351_G	0.600	0.48
201_D	205_N	0.600	0.48
373_E	397_N	0.599	0.48
108_N	201_D	0.597	0.48
326_N	330_S	0.597	0.48
208_K	252_D	0.596	0.48
130_L	327_V	0.596	0.48
148_R	152_K	0.595	0.48
382_R	388_V	0.595	0.48
44_A	108_N	0.595	0.48
44_A	70_L	0.594	0.48
198_Y	203_V	0.593	0.47
332_R	335_D	0.593	0.47
457_A	468_K	0.591	0.47
157_N	174_I	0.591	0.47
386_D	511_P	0.591	0.47
11_S	207_W	0.591	0.47
88_Y	187_G	0.590	0.47
294_I	309_P	0.589	0.47
358_V	375_I	0.589	0.47
4_W	7_I	0.589	0.47
196_D	494_K	0.588	0.47
138_Y	170_P	0.586	0.47
69_T	84_L	0.586	0.47
193_Q	508_Y	0.584	0.46
166_N	170_P	0.583	0.46
29_P	51_Q	0.581	0.46
422_N	510_T	0.581	0.46
75_E	157_N	0.580	0.46
191_I	195_F	0.580	0.46
446_R	489_S	0.580	0.46
273_A	278_T	0.579	0.46
126_M	131_N	0.578	0.46
430_K	465_G	0.578	0.46
253_E	257_Y	0.577	0.46
217_L	220_S	0.576	0.46
142_F	166_N	0.576	0.46
31_I	392_Q	0.575	0.45
14_I	280_S	0.575	0.45
449_I	498_I	0.574	0.45
328_E	372_Y	0.574	0.45
373_E	398_T	0.574	0.45
11_S	203_V	0.573	0.45
247_L	340_A	0.573	0.45
213_Y	216_K	0.572	0.45
86_D	89_T	0.572	0.45
107_G	111_G	0.572	0.45
118_H	176_D	0.571	0.45
48_I	301_Y	0.571	0.45
111_G	203_V	0.571	0.45
261_A	310_K	0.570	0.45
423_S	433_D	0.570	0.45
105_Y	108_N	0.570	0.45
121_D	452_E	0.569	0.45
35_M	53_E	0.568	0.45
152_K	229_I	0.568	0.45
41_I	103_V	0.568	0.45
4_W	209_T	0.567	0.45
473_T	480_R	0.567	0.45
67_K	70_L	0.567	0.45
273_A	277_V	0.566	0.44
229_I	251_V	0.566	0.44
35_M	409_Y	0.565	0.44
307_D	310_K	0.564	0.44
81_M	99_V	0.564	0.44
97_V	144_I	0.564	0.44
355_M	374_T	0.564	0.44
119_Q	287_R	0.563	0.44
227_N	255_G	0.563	0.44
38_S	280_S	0.563	0.44
44_A	252_D	0.562	0.44
46_G	124_G	0.562	0.44
258_A	341_L	0.561	0.44
34_R	396_T	0.561	0.44
327_V	372_Y	0.560	0.44
16_E	19_G	0.560	0.44
257_Y	261_A	0.560	0.44
171_E	249_V	0.560	0.44
21_M	189_A	0.559	0.44
88_Y	145_P	0.559	0.44
422_N	430_K	0.557	0.43
26_A	33_E	0.557	0.43
83_V	163_I	0.556	0.43
69_T	73_I	0.556	0.43
2_T	174_I	0.556	0.43
231_E	244_K	0.555	0.43
256_V	286_I	0.555	0.43
56_P	62_F	0.555	0.43
158_E	196_D	0.554	0.43
232_D	350_A	0.554	0.43
327_V	357_N	0.553	0.43
247_L	260_F	0.553	0.43
66_V	100_L	0.553	0.43
8_Y	12_E	0.552	0.43
30_N	355_M	0.552	0.43
201_D	510_T	0.552	0.43
71_N	89_T	0.551	0.43
143_V	146_P	0.550	0.43
304_I	336_V	0.550	0.43
15_A	50_A	0.549	0.43
426_V	511_P	0.549	0.43
44_A	304_I	0.548	0.42
259_N	307_D	0.548	0.42
42_T	58_H	0.547	0.42
492_L	496_D	0.547	0.42
334_A	395_M	0.547	0.42
310_K	494_K	0.546	0.42
31_I	398_T	0.545	0.42
468_K	501_E	0.545	0.42
69_T	186_N	0.544	0.42
136_T	226_G	0.543	0.42
124_G	297_N	0.542	0.42
38_S	54_H	0.542	0.42
65_G	68_N	0.542	0.42
154_E	196_D	0.541	0.42
275_Y	310_K	0.540	0.42
352_S	503_P	0.540	0.42
108_N	154_E	0.539	0.41
262_G	315_N	0.538	0.41
417_Y	435_I	0.538	0.41
80_D	104_Y	0.538	0.41
223_S	255_G	0.535	0.41
189_A	223_S	0.535	0.41
56_P	60_G	0.534	0.41
22_L	115_N	0.533	0.41
386_D	507_G	0.533	0.41
41_I	323_G	0.533	0.41
240_D	313_I	0.533	0.41
273_A	326_N	0.533	0.41
200_Y	222_I	0.532	0.41
171_E	185_L	0.532	0.41
348_P	459_W	0.532	0.41
123_G	168_K	0.532	0.41
356_M	454_F	0.532	0.41
224_K	253_E	0.531	0.41
223_S	510_T	0.531	0.41
476_R	481_K	0.530	0.40
205_N	209_T	0.530	0.40
167_F	177_L	0.530	0.40
37_H	53_E	0.530	0.40
82_I	112_Y	0.530	0.40
246_R	262_G	0.530	0.40
125_P	131_N	0.529	0.40
192_K	223_S	0.529	0.40
202_N	206_A	0.529	0.40
145_P	166_N	0.529	0.40
189_A	192_K	0.528	0.40
281_A	337_T	0.528	0.40
260_F	309_P	0.528	0.40
244_K	455_R	0.527	0.40
374_T	395_M	0.527	0.40
435_I	457_A	0.527	0.40
507_G	511_P	0.527	0.40
57_V	401_T	0.526	0.40
392_Q	396_T	0.526	0.40
376_G	390_A	0.526	0.40
201_D	481_K	0.525	0.40
171_E	174_I	0.525	0.40
23_K	48_I	0.522	0.40
143_V	166_N	0.521	0.39
191_I	482_E	0.521	0.39
72_Q	89_T	0.521	0.39
57_V	183_A	0.521	0.39
327_V	359_M	0.520	0.39
101_A	185_L	0.520	0.39
69_T	146_P	0.520	0.39
473_T	478_D	0.520	0.39
78_E	108_N	0.519	0.39
284_F	331_Q	0.518	0.39
107_G	216_K	0.518	0.39
122_V	183_A	0.517	0.39
32_R	397_N	0.517	0.39
71_N	193_Q	0.517	0.39
374_T	392_Q	0.516	0.39
391_V	397_N	0.516	0.39
377_G	431_G	0.516	0.39
252_D	310_K	0.516	0.39
106_N	200_Y	0.516	0.39
287_R	324_G	0.516	0.39
271_L	313_I	0.516	0.39
378_G	434_G	0.515	0.39
24_R	67_K	0.515	0.39
474_I	496_D	0.515	0.39
376_G	392_Q	0.515	0.39
114_V	335_D	0.515	0.39
465_G	510_T	0.514	0.39
249_V	285_V	0.514	0.39
175_G	402_P	0.514	0.39
196_D	228_G	0.514	0.39
22_L	30_N	0.514	0.39
52_A	396_T	0.513	0.39
158_E	161_N	0.513	0.39
173_S	405_I	0.513	0.39
405_I	409_Y	0.512	0.38
238_I	487_K	0.512	0.38
151_R	481_K	0.512	0.38
71_N	196_D	0.511	0.38
28_S	117_A	0.511	0.38
130_L	270_P	0.511	0.38
356_M	470_A	0.511	0.38
202_N	205_N	0.510	0.38
337_T	488_F	0.510	0.38
281_A	330_S	0.510	0.38
57_V	326_N	0.510	0.38
476_R	493_N	0.509	0.38
33_E	36_D	0.509	0.38
260_F	314_V	0.509	0.38
20_V	26_A	0.508	0.38
121_D	132_P	0.508	0.38
18_M	37_H	0.507	0.38
105_Y	189_A	0.507	0.38
325_G	328_E	0.507	0.38
284_F	395_M	0.507	0.38
130_L	323_G	0.506	0.38
160_I	174_I	0.505	0.38
230_G	254_N	0.505	0.38
451_A	488_F	0.505	0.38
362_G	367_K	0.505	0.38
298_E	304_I	0.504	0.38
106_N	154_E	0.504	0.38
165_H	419_I	0.503	0.37
76_L	80_D	0.503	0.37
221_E	298_E	0.503	0.37
126_M	134_A	0.503	0.37
181_I	185_L	0.502	0.37
71_N	108_N	0.501	0.37
83_V	147_V	0.501	0.37
428_K	508_Y	0.501	0.37
429_Y	443_E	0.501	0.37
132_P	442_L	0.501	0.37
116_K	326_N	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2kzxA	1	0.232	40.4	0.98	Contact Map
1j5kA	1	0.1287	27.7	0.981	Contact Map
3by8A	2	0.23	23.2	0.982	Contact Map
2yfqA	5	0.3606	23.1	0.982	Contact Map
1p0zA	4	0.2144	19.5	0.983	Contact Map
3k92A	5	0.4055	19.3	0.983	Contact Map
4dzoA	2	0.23	16.9	0.983	Contact Map
2oa5A	4	0.1696	16.8	0.983	Contact Map
1txjA	1	0.2671	16.4	0.983	Contact Map
3aoeE	3	0.3938	16.4	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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