Q97UN8 - SULSO - GREMLIN Contacts

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Q97UN8 - Na(+)/H(+) antiporter, putative

UniProt:	Q97UN8	Sequences: MMDYALLSLMLLFTLLLAFILTRLKVSPVIAYLLGGLISFNYFHFDFNSSYFEILNFLALNLLAFEIGTSFDISRAKELFRRAMGIALTELILIVLISYFIGLYLLHLDLFASLFLVMASIDTSTSILYKIIGNKVDKNDRDLLVAVASVEDIEVFFLYSIAIALNGSFNVFRISFVILEVFIASLIIYAFAKYFLTGLSIFKFTSFEDESILILVPIVLVFVFEYISQVTQVPATLTMILAGIAFSSISGSEKVLRYTGPIREFSLIFFFLSVGSYLKITAGISTFVLISFIILAIKYFSFSTASWVSGTTLVKAFTNGLYMLPLSEFGIIVSLQALQQGIDIAIVYYISVVVVLVSSIIASILAVRVNVLQRVIGIVYSRSYFLRQLDSTIIWLNKTLSTNLSPILRSVLFRGFVKMFLYLILPYVLFPIINSIVKSIIDPINNLILQYLLYSGEIVIALFLLYLFLLEGSRLYSIINNEILVRIVRVRSRLFKEFWFGLTSFSSTFYTIILTIIYIIFEIIPLLYNFPIRLVFVPLLISLYFIYRYRAPPITYTRIDNKEADKIVKLSVKVIKKMRKRRSKRSIISTTKTVRREWS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	599 (511)
Sequences:	5251 (3855)
Seq/√Len:	170.5

ECOLI - KEFC KEFB YBAL NHAP2 YJCE
BACSU - YJBQ NHAK
HALSA - Q9HNK1
SULSO - Q97UN8 Q980D8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
393_I	396_L	5.581	1.00
459_V	476_Y	5.279	1.00
392_T	395_W	4.477	1.00
494_L	498_F	4.060	1.00
395_W	398_K	3.873	1.00
163_I	166_N	3.672	1.00
303_S	320_G	3.476	1.00
291_S	357_V	3.370	1.00
100_F	105_L	3.347	1.00
303_S	313_L	3.179	1.00
198_G	201_I	3.092	1.00
507_S	510_Y	2.968	1.00
373_Q	376_I	2.865	1.00
179_L	183_I	2.839	1.00
461_A	473_S	2.833	1.00
502_L	505_F	2.775	1.00
394_I	397_N	2.641	1.00
172_F	176_F	2.598	1.00
99_Y	117_V	2.570	1.00
510_Y	513_I	2.561	1.00
175_S	179_L	2.502	1.00
334_S	351_S	2.484	1.00
392_T	396_L	2.454	1.00
393_I	397_N	2.432	1.00
176_F	180_E	2.388	1.00
50_S	53_E	2.380	1.00
288_V	292_F	2.287	1.00
99_Y	114_L	2.249	1.00
17_L	38_I	2.228	1.00
459_V	483_I	2.210	1.00
501_G	505_F	2.182	1.00
502_L	506_S	2.177	1.00
102_G	113_S	2.158	1.00
509_F	513_I	2.150	1.00
171_V	175_S	2.134	1.00
511_T	515_T	2.108	1.00
511_T	516_I	2.105	1.00
398_K	409_R	2.087	1.00
476_Y	483_I	2.077	1.00
99_Y	110_L	2.062	1.00
285_S	289_L	2.059	1.00
97_I	301_S	2.054	1.00
119_A	334_S	2.041	1.00
367_V	371_V	2.041	1.00
463_F	469_L	2.036	1.00
507_S	511_T	2.032	1.00
372_L	376_I	2.027	1.00
344_I	347_V	1.966	1.00
350_I	354_V	1.965	1.00
461_A	469_L	1.965	1.00
497_E	500_F	1.942	1.00
163_I	167_G	1.940	1.00
476_Y	480_N	1.933	1.00
12_L	219_V	1.930	1.00
190_A	194_Y	1.912	1.00
330_G	355_V	1.912	1.00
395_W	457_E	1.911	1.00
425_L	428_V	1.899	1.00
109_D	112_A	1.884	1.00
507_S	512_I	1.877	1.00
290_I	354_V	1.875	1.00
99_Y	104_Y	1.863	1.00
394_I	398_K	1.862	1.00
293_I	297_I	1.844	1.00
307_W	313_L	1.836	1.00
96_L	100_F	1.828	1.00
307_W	310_G	1.820	1.00
507_S	513_I	1.818	1.00
292_F	296_A	1.806	1.00
371_V	375_V	1.793	1.00
387_R	390_D	1.792	1.00
325_P	362_A	1.791	1.00
453_L	459_V	1.791	1.00
461_A	465_L	1.787	1.00
474_R	478_I	1.755	1.00
306_S	316_A	1.749	1.00
477_S	485_V	1.746	1.00
95_V	118_M	1.737	1.00
254_K	258_Y	1.732	1.00
74_S	78_E	1.729	1.00
452_L	455_S	1.678	1.00
495_F	500_F	1.672	1.00
173_R	176_F	1.647	1.00
495_F	499_W	1.647	1.00
97_I	297_I	1.634	1.00
287_F	350_I	1.632	1.00
338_L	348_Y	1.631	1.00
223_V	227_I	1.630	1.00
144_L	322_Y	1.627	1.00
279_K	349_Y	1.625	1.00
453_L	480_N	1.617	1.00
513_I	516_I	1.615	1.00
303_S	307_W	1.597	1.00
451_Y	458_I	1.579	1.00
393_I	398_K	1.575	1.00
319_N	322_Y	1.572	1.00
465_L	468_F	1.557	1.00
5_A	8_S	1.553	1.00
116_L	351_S	1.551	1.00
472_G	476_Y	1.549	1.00
384_Y	387_R	1.530	1.00
184_A	188_I	1.518	1.00
77_K	80_F	1.512	1.00
461_A	472_G	1.512	1.00
423_L	428_V	1.496	1.00
501_G	504_S	1.479	1.00
370_N	373_Q	1.477	1.00
493_R	497_E	1.471	1.00
373_Q	380_Y	1.471	1.00
21_L	34_L	1.469	1.00
497_E	501_G	1.467	1.00
428_V	431_P	1.463	1.00
291_S	358_S	1.461	1.00
494_L	497_E	1.458	1.00
447_L	451_Y	1.450	1.00
294_I	358_S	1.449	1.00
144_L	319_N	1.448	1.00
494_L	500_F	1.444	1.00
321_L	365_L	1.430	1.00
452_L	456_G	1.427	1.00
369_V	373_Q	1.426	1.00
495_F	498_F	1.410	1.00
197_T	250_S	1.401	1.00
317_F	320_G	1.391	1.00
123_T	128_L	1.390	1.00
397_N	400_L	1.387	1.00
449_L	454_Y	1.384	1.00
195_F	198_G	1.382	1.00
384_Y	388_Q	1.379	1.00
509_F	512_I	1.378	1.00
115_F	337_A	1.376	1.00
335_L	339_Q	1.371	1.00
185_S	189_Y	1.367	1.00
123_T	323_M	1.354	1.00
306_S	311_T	1.353	1.00
336_Q	340_Q	1.351	1.00
297_I	301_S	1.347	1.00
336_Q	339_Q	1.337	1.00
385_F	388_Q	1.335	1.00
399_T	402_T	1.334	1.00
183_I	187_I	1.330	1.00
494_L	499_W	1.318	1.00
304_T	308_V	1.314	1.00
95_V	158_L	1.312	1.00
13_F	39_S	1.310	1.00
326_L	330_G	1.307	1.00
127_I	359_S	1.306	1.00
284_I	288_V	1.301	1.00
386_L	389_L	1.300	1.00
39_S	276_S	1.300	1.00
326_L	355_V	1.297	1.00
491_R	494_L	1.293	1.00
451_Y	456_G	1.284	1.00
393_I	455_S	1.281	1.00
198_G	203_K	1.279	1.00
100_F	104_Y	1.274	1.00
64_A	122_D	1.274	1.00
392_T	397_N	1.273	1.00
22_T	25_K	1.264	1.00
295_L	361_I	1.263	1.00
432_I	437_V	1.263	1.00
510_Y	514_L	1.263	1.00
191_F	194_Y	1.260	1.00
492_S	495_F	1.259	1.00
294_I	326_L	1.259	1.00
165_L	169_F	1.253	1.00
187_I	190_A	1.248	1.00
94_I	302_F	1.246	1.00
507_S	514_L	1.244	1.00
429_L	439_S	1.242	1.00
376_I	379_V	1.239	1.00
508_T	513_I	1.238	1.00
174_I	177_V	1.238	1.00
508_T	512_I	1.233	1.00
132_I	141_R	1.231	1.00
48_N	51_Y	1.220	1.00
225_E	235_A	1.220	1.00
299_Y	321_L	1.218	1.00
143_L	311_T	1.217	1.00
128_L	322_Y	1.214	1.00
397_N	402_T	1.209	1.00
94_I	98_S	1.205	1.00
510_Y	515_T	1.201	1.00
512_I	515_T	1.193	1.00
512_I	516_I	1.192	1.00
148_A	151_E	1.192	1.00
502_L	507_S	1.192	1.00
61_N	225_E	1.191	1.00
484_L	487_I	1.188	1.00
337_A	341_G	1.186	1.00
53_E	273_S	1.184	1.00
92_I	96_L	1.181	1.00
423_L	429_L	1.179	1.00
448_I	456_G	1.173	1.00
503_T	506_S	1.173	1.00
505_F	513_I	1.167	1.00
294_I	354_V	1.161	1.00
422_Y	440_I	1.160	1.00
140_D	315_K	1.159	1.00
96_L	99_Y	1.156	1.00
88_L	92_I	1.155	1.00
86_I	305_A	1.153	1.00
229_Q	235_A	1.153	1.00
506_S	510_Y	1.150	1.00
279_K	282_A	1.148	1.00
158_L	333_V	1.147	1.00
312_T	316_A	1.146	1.00
428_V	432_I	1.138	1.00
489_R	495_F	1.131	1.00
502_L	511_T	1.123	1.00
318_T	369_V	1.114	1.00
499_W	502_L	1.105	1.00
510_Y	516_I	1.104	1.00
147_V	319_N	1.103	1.00
463_F	468_F	1.103	1.00
505_F	511_T	1.100	1.00
447_L	450_Q	1.100	1.00
501_G	513_I	1.100	1.00
431_P	435_S	1.095	1.00
385_F	389_L	1.094	1.00
181_V	233_V	1.092	1.00
87_A	90_E	1.091	1.00
164_A	168_S	1.091	1.00
91_L	154_E	1.088	1.00
498_F	506_S	1.087	1.00
118_M	158_L	1.078	1.00
79_L	82_R	1.077	1.00
348_Y	352_V	1.076	1.00
426_P	430_F	1.075	1.00
289_L	293_I	1.073	1.00
483_I	488_V	1.064	1.00
429_L	432_I	1.063	1.00
98_S	102_G	1.059	1.00
278_L	356_L	1.056	0.99
359_S	362_A	1.053	0.99
171_V	174_I	1.048	0.99
286_T	350_I	1.037	0.99
476_Y	481_N	1.035	0.99
345_A	349_Y	1.035	0.99
279_K	345_A	1.033	0.99
436_I	442_D	1.031	0.99
15_L	18_A	1.029	0.99
27_S	119_A	1.027	0.99
72_D	248_S	1.026	0.99
27_S	130_K	1.023	0.99
102_G	290_I	1.022	0.99
250_S	433_I	1.015	0.99
225_E	239_M	1.014	0.99
283_G	346_I	1.013	0.99
492_S	498_F	1.012	0.99
191_F	195_F	1.009	0.99
117_V	121_I	1.006	0.99
390_D	395_W	1.006	0.99
102_G	108_L	1.004	0.99
120_S	294_I	1.003	0.99
509_F	516_I	1.003	0.99
122_D	155_V	1.000	0.99
361_I	365_L	0.997	0.99
368_R	371_V	0.997	0.99
409_R	412_L	0.997	0.99
140_D	318_T	0.996	0.99
451_Y	455_S	0.995	0.99
172_F	175_S	0.995	0.99
505_F	516_I	0.995	0.99
432_I	435_S	0.988	0.99
397_N	456_G	0.987	0.99
492_S	497_E	0.981	0.99
194_Y	198_G	0.979	0.99
431_P	434_N	0.978	0.99
460_I	463_F	0.976	0.99
108_L	113_S	0.976	0.99
147_V	323_M	0.970	0.99
498_F	502_L	0.969	0.99
488_V	491_R	0.969	0.99
318_T	322_Y	0.965	0.99
392_T	398_K	0.965	0.99
493_R	499_W	0.964	0.99
165_L	170_N	0.962	0.99
511_T	514_L	0.960	0.99
8_S	12_L	0.959	0.99
140_D	319_N	0.959	0.99
496_K	499_W	0.958	0.99
189_Y	193_K	0.958	0.99
51_Y	54_I	0.958	0.99
477_S	480_N	0.957	0.99
402_T	405_S	0.956	0.99
83_A	150_V	0.955	0.99
288_V	291_S	0.954	0.99
505_F	510_Y	0.952	0.99
387_R	391_S	0.948	0.99
176_F	179_L	0.946	0.99
101_I	105_L	0.945	0.99
337_A	340_Q	0.945	0.99
72_D	75_R	0.938	0.99
15_L	219_V	0.938	0.99
15_L	216_V	0.936	0.99
284_I	287_F	0.929	0.99
162_A	340_Q	0.927	0.99
84_M	88_L	0.927	0.99
79_L	83_A	0.925	0.99
273_S	277_Y	0.923	0.99
290_I	350_I	0.919	0.99
484_L	489_R	0.919	0.99
411_V	415_G	0.918	0.99
36_G	40_F	0.916	0.99
473_S	485_V	0.914	0.99
388_Q	394_I	0.913	0.99
286_T	289_L	0.913	0.99
128_L	323_M	0.912	0.99
459_V	462_L	0.911	0.99
82_R	146_A	0.911	0.99
26_V	33_L	0.911	0.99
390_D	394_I	0.911	0.99
177_V	180_E	0.908	0.98
399_T	472_G	0.906	0.98
477_S	503_T	0.906	0.98
38_I	43_F	0.905	0.98
115_F	119_A	0.902	0.98
413_F	419_M	0.901	0.98
487_I	498_F	0.901	0.98
380_Y	383_S	0.901	0.98
449_L	452_L	0.900	0.98
466_Y	473_S	0.895	0.98
505_F	512_I	0.892	0.98
10_M	18_A	0.886	0.98
220_L	242_A	0.884	0.98
197_T	249_I	0.884	0.98
355_V	359_S	0.882	0.98
351_S	364_I	0.882	0.98
385_F	392_T	0.875	0.98
120_S	351_S	0.874	0.98
8_S	226_Y	0.873	0.98
405_S	423_L	0.869	0.98
83_A	98_S	0.869	0.98
505_F	509_F	0.867	0.98
59_A	270_F	0.866	0.98
373_Q	377_G	0.865	0.98
148_A	329_F	0.864	0.98
446_N	454_Y	0.864	0.98
132_I	136_V	0.864	0.98
412_L	415_G	0.862	0.98
298_K	323_M	0.861	0.98
10_M	52_F	0.860	0.98
206_S	427_Y	0.857	0.98
84_M	87_A	0.856	0.98
407_I	410_S	0.855	0.98
366_A	369_V	0.854	0.98
37_L	183_I	0.850	0.98
385_F	394_I	0.849	0.98
226_Y	230_V	0.845	0.98
186_L	190_A	0.845	0.98
427_Y	430_F	0.844	0.98
85_G	309_S	0.842	0.97
399_T	459_V	0.841	0.97
444_I	472_G	0.840	0.97
493_R	500_F	0.840	0.97
91_L	150_V	0.834	0.97
286_T	290_I	0.834	0.97
34_L	38_I	0.833	0.97
338_L	345_A	0.833	0.97
386_L	394_I	0.830	0.97
188_I	245_A	0.827	0.97
385_F	395_W	0.824	0.97
496_K	500_F	0.824	0.97
147_V	298_K	0.823	0.97
498_F	505_F	0.823	0.97
101_I	293_I	0.823	0.97
461_A	466_Y	0.823	0.97
39_S	45_F	0.822	0.97
499_W	503_T	0.821	0.97
106_L	286_T	0.820	0.97
48_N	54_I	0.819	0.97
461_A	476_Y	0.819	0.97
403_N	488_V	0.819	0.97
507_S	516_I	0.817	0.97
357_V	361_I	0.816	0.97
468_F	471_E	0.812	0.97
507_S	515_T	0.811	0.97
125_T	148_A	0.810	0.97
124_S	151_E	0.810	0.97
501_G	507_S	0.806	0.97
16_L	20_I	0.805	0.97
39_S	42_Y	0.804	0.97
246_F	255_V	0.802	0.97
100_F	176_F	0.800	0.97
449_L	479_I	0.799	0.97
377_G	380_Y	0.797	0.97
384_Y	389_L	0.797	0.97
371_V	374_R	0.796	0.96
480_N	483_I	0.796	0.96
104_Y	110_L	0.795	0.96
151_E	329_F	0.794	0.96
314_V	318_T	0.794	0.96
400_L	405_S	0.793	0.96
492_S	496_K	0.792	0.96
481_N	485_V	0.791	0.96
321_L	369_V	0.791	0.96
471_E	474_R	0.788	0.96
86_I	309_S	0.786	0.96
163_I	168_S	0.786	0.96
504_S	512_I	0.785	0.96
90_E	302_F	0.784	0.96
494_L	502_L	0.784	0.96
82_R	143_L	0.784	0.96
94_I	301_S	0.781	0.96
453_L	479_I	0.781	0.96
262_I	266_S	0.780	0.96
504_S	510_Y	0.778	0.96
401_S	409_R	0.777	0.96
484_L	488_V	0.776	0.96
389_L	394_I	0.773	0.96
463_F	472_G	0.773	0.96
59_A	238_T	0.771	0.96
412_L	416_F	0.769	0.96
166_N	169_F	0.766	0.96
396_L	400_L	0.765	0.96
119_A	351_S	0.763	0.96
86_I	302_F	0.763	0.96
502_L	509_F	0.762	0.96
446_N	449_L	0.760	0.95
90_E	94_I	0.758	0.95
112_A	347_V	0.757	0.95
6_L	10_M	0.756	0.95
119_A	333_V	0.756	0.95
499_W	504_S	0.755	0.95
92_I	95_V	0.755	0.95
463_F	466_Y	0.755	0.95
435_S	440_I	0.754	0.95
178_I	189_Y	0.754	0.95
41_N	276_S	0.754	0.95
509_F	515_T	0.754	0.95
86_I	90_E	0.751	0.95
283_G	286_T	0.750	0.95
173_R	177_V	0.743	0.95
284_I	334_S	0.740	0.95
359_S	363_S	0.738	0.95
509_F	514_L	0.738	0.95
183_I	186_L	0.738	0.95
385_F	390_D	0.737	0.95
398_K	460_I	0.736	0.95
68_G	240_I	0.736	0.95
481_N	488_V	0.735	0.95
239_M	270_F	0.735	0.95
270_F	363_S	0.734	0.95
466_Y	469_L	0.734	0.95
427_Y	431_P	0.734	0.95
218_I	221_V	0.733	0.94
460_I	464_L	0.732	0.94
65_F	68_G	0.732	0.94
417_V	422_Y	0.731	0.94
411_V	414_R	0.729	0.94
372_L	375_V	0.728	0.94
410_S	414_R	0.728	0.94
444_I	463_F	0.724	0.94
188_I	241_L	0.722	0.94
145_V	331_I	0.721	0.94
18_A	31_A	0.718	0.94
18_A	21_L	0.718	0.94
411_V	432_I	0.718	0.94
291_S	295_L	0.716	0.94
418_K	425_L	0.716	0.94
470_L	473_S	0.716	0.94
364_I	368_R	0.715	0.94
388_Q	391_S	0.715	0.94
391_S	395_W	0.714	0.94
404_L	516_I	0.713	0.94
108_L	116_L	0.713	0.94
452_L	458_I	0.712	0.94
390_D	393_I	0.712	0.94
76_A	83_A	0.710	0.93
156_F	333_V	0.710	0.93
320_G	323_M	0.710	0.93
127_I	267_L	0.709	0.93
501_G	506_S	0.707	0.93
299_Y	320_G	0.706	0.93
218_I	262_I	0.704	0.93
388_Q	392_T	0.702	0.93
430_F	434_N	0.701	0.93
147_V	151_E	0.701	0.93
38_I	182_F	0.699	0.93
279_K	298_K	0.699	0.93
384_Y	392_T	0.698	0.93
505_F	515_T	0.696	0.93
501_G	512_I	0.696	0.93
470_L	497_E	0.694	0.93
354_V	362_A	0.692	0.93
316_A	320_G	0.692	0.93
193_K	245_A	0.691	0.93
448_I	451_Y	0.690	0.92
112_A	344_I	0.690	0.92
306_S	319_N	0.689	0.92
89_T	92_I	0.688	0.92
368_R	372_L	0.687	0.92
123_T	155_V	0.687	0.92
88_L	150_V	0.686	0.92
107_H	110_L	0.686	0.92
193_K	196_L	0.686	0.92
317_F	321_L	0.685	0.92
61_N	235_A	0.683	0.92
475_L	480_N	0.683	0.92
177_V	181_V	0.683	0.92
498_F	501_G	0.683	0.92
483_I	487_I	0.682	0.92
439_S	442_D	0.679	0.92
21_L	25_K	0.675	0.92
155_V	159_Y	0.675	0.92
271_F	275_G	0.674	0.92
413_F	437_V	0.673	0.92
473_S	502_L	0.670	0.91
94_I	151_E	0.670	0.91
83_A	90_E	0.669	0.91
83_A	102_G	0.669	0.91
494_L	506_S	0.668	0.91
86_I	299_Y	0.666	0.91
28_P	32_Y	0.666	0.91
466_Y	471_E	0.665	0.91
109_D	113_S	0.663	0.91
79_L	87_A	0.663	0.91
123_T	151_E	0.661	0.91
8_S	222_F	0.660	0.91
501_G	516_I	0.660	0.91
69_T	246_F	0.660	0.91
433_I	437_V	0.659	0.91
373_Q	379_V	0.659	0.91
420_F	485_V	0.658	0.91
128_L	325_P	0.658	0.91
470_L	474_R	0.657	0.91
448_I	453_L	0.656	0.90
392_T	400_L	0.656	0.90
74_S	77_K	0.656	0.90
328_E	332_I	0.656	0.90
328_E	331_I	0.655	0.90
78_E	81_R	0.654	0.90
465_L	470_L	0.654	0.90
171_V	176_F	0.654	0.90
41_N	44_H	0.654	0.90
10_M	272_L	0.653	0.90
108_L	347_V	0.651	0.90
97_I	100_F	0.649	0.90
122_D	148_A	0.646	0.90
399_T	444_I	0.646	0.90
70_S	126_S	0.645	0.90
495_F	502_L	0.643	0.90
475_L	478_I	0.643	0.90
302_F	319_N	0.641	0.89
122_D	267_L	0.640	0.89
368_R	373_Q	0.639	0.89
397_N	401_S	0.638	0.89
102_G	347_V	0.638	0.89
229_Q	255_V	0.636	0.89
73_I	77_K	0.635	0.89
111_F	114_L	0.635	0.89
66_E	255_V	0.633	0.89
500_F	506_S	0.633	0.89
473_S	476_Y	0.633	0.89
370_N	376_I	0.632	0.89
101_I	297_I	0.632	0.89
407_I	411_V	0.631	0.89
388_Q	393_I	0.631	0.89
448_I	455_S	0.631	0.89
384_Y	391_S	0.630	0.89
502_L	515_T	0.628	0.89
120_S	326_L	0.628	0.89
370_N	374_R	0.628	0.89
306_S	320_G	0.627	0.88
32_Y	268_I	0.626	0.88
508_T	511_T	0.626	0.88
93_L	301_S	0.626	0.88
226_Y	281_T	0.624	0.88
322_Y	366_A	0.623	0.88
492_S	507_S	0.622	0.88
501_G	511_T	0.622	0.88
156_F	325_P	0.622	0.88
95_V	121_I	0.620	0.88
122_D	125_T	0.619	0.88
124_S	270_F	0.619	0.88
250_S	253_E	0.618	0.88
387_R	394_I	0.615	0.87
270_F	328_E	0.613	0.87
490_V	494_L	0.613	0.87
504_S	514_L	0.613	0.87
93_L	305_A	0.612	0.87
451_Y	457_E	0.609	0.87
501_G	509_F	0.607	0.87
371_V	379_V	0.607	0.87
179_L	357_V	0.607	0.87
40_F	276_S	0.606	0.87
372_L	379_V	0.605	0.87
283_G	350_I	0.604	0.87
66_E	260_G	0.602	0.86
174_I	178_I	0.601	0.86
278_L	294_I	0.601	0.86
422_Y	447_L	0.601	0.86
147_V	327_S	0.601	0.86
125_T	276_S	0.601	0.86
126_S	268_I	0.600	0.86
166_N	183_I	0.600	0.86
466_Y	494_L	0.600	0.86
37_L	280_I	0.599	0.86
20_I	23_R	0.599	0.86
187_I	191_F	0.598	0.86
484_L	503_T	0.598	0.86
514_L	517_I	0.595	0.86
485_V	503_T	0.595	0.86
486_R	490_V	0.595	0.86
332_I	355_V	0.594	0.86
175_S	178_I	0.594	0.86
68_G	244_I	0.593	0.86
422_Y	434_N	0.593	0.86
61_N	239_M	0.590	0.85
115_F	235_A	0.590	0.85
102_G	117_V	0.589	0.85
502_L	510_Y	0.589	0.85
370_N	379_V	0.589	0.85
56_N	59_A	0.587	0.85
426_P	429_L	0.586	0.85
260_G	264_E	0.586	0.85
370_N	380_Y	0.585	0.85
504_S	515_T	0.585	0.85
105_L	172_F	0.584	0.85
71_F	247_S	0.584	0.85
372_L	378_I	0.583	0.85
201_I	250_S	0.581	0.84
403_N	406_P	0.581	0.84
123_T	126_S	0.581	0.84
499_W	506_S	0.579	0.84
495_F	504_S	0.579	0.84
455_S	458_I	0.578	0.84
203_K	206_S	0.575	0.84
67_I	122_D	0.575	0.84
91_L	121_I	0.575	0.84
131_I	253_E	0.575	0.84
224_F	245_A	0.574	0.84
131_I	322_Y	0.574	0.84
128_L	156_F	0.570	0.83
513_I	517_I	0.570	0.83
307_W	316_A	0.570	0.83
459_V	472_G	0.569	0.83
301_S	305_A	0.569	0.83
287_F	290_I	0.568	0.83
495_F	501_G	0.568	0.83
454_Y	482_E	0.568	0.83
376_I	381_S	0.564	0.83
196_L	246_F	0.564	0.83
182_F	186_L	0.562	0.82
504_S	513_I	0.562	0.82
398_K	402_T	0.560	0.82
415_G	422_Y	0.560	0.82
310_G	313_L	0.560	0.82
132_I	266_S	0.560	0.82
52_F	273_S	0.559	0.82
459_V	463_F	0.559	0.82
351_S	355_V	0.558	0.82
171_V	183_I	0.558	0.82
64_A	236_T	0.558	0.82
296_A	387_R	0.557	0.82
101_I	289_L	0.557	0.82
255_V	259_T	0.557	0.82
238_T	270_F	0.556	0.82
510_Y	517_I	0.555	0.82
80_F	84_M	0.554	0.81
464_L	469_L	0.553	0.81
327_S	331_I	0.553	0.81
471_E	475_L	0.552	0.81
56_N	238_T	0.550	0.81
146_A	278_L	0.549	0.81
180_E	183_I	0.549	0.81
209_D	213_L	0.549	0.81
351_S	356_L	0.549	0.81
56_N	273_S	0.547	0.81
156_F	332_I	0.547	0.81
322_Y	325_P	0.547	0.81
188_I	193_K	0.547	0.81
128_L	148_A	0.545	0.80
151_E	298_K	0.544	0.80
123_T	326_L	0.544	0.80
495_F	505_F	0.544	0.80
434_N	447_L	0.544	0.80
119_A	343_D	0.543	0.80
460_I	465_L	0.542	0.80
178_I	351_S	0.542	0.80
424_I	428_V	0.542	0.80
93_L	97_I	0.541	0.80
236_T	331_I	0.540	0.80
403_N	464_L	0.539	0.80
346_I	350_I	0.538	0.80
122_D	126_S	0.538	0.80
404_L	407_I	0.537	0.79
106_L	290_I	0.537	0.79
185_S	188_I	0.536	0.79
252_S	256_L	0.536	0.79
156_F	236_T	0.534	0.79
68_G	239_M	0.534	0.79
179_L	187_I	0.534	0.79
129_Y	187_I	0.533	0.79
178_I	181_V	0.533	0.79
311_T	315_K	0.533	0.79
152_D	234_P	0.531	0.79
129_Y	145_V	0.530	0.79
122_D	130_K	0.530	0.79
467_L	470_L	0.530	0.79
71_F	248_S	0.530	0.79
167_G	341_G	0.529	0.78
61_N	64_A	0.529	0.78
409_R	419_M	0.528	0.78
396_L	399_T	0.527	0.78
430_F	433_I	0.527	0.78
42_Y	279_K	0.527	0.78
403_N	490_V	0.526	0.78
254_K	257_R	0.526	0.78
164_A	167_G	0.526	0.78
449_L	458_I	0.526	0.78
66_E	70_S	0.525	0.78
444_I	448_I	0.523	0.78
499_W	505_F	0.522	0.78
404_L	412_L	0.522	0.78
125_T	270_F	0.522	0.78
49_S	52_F	0.522	0.78
386_L	390_D	0.521	0.77
433_I	440_I	0.521	0.77
361_I	386_L	0.521	0.77
10_M	219_V	0.520	0.77
102_G	301_S	0.520	0.77
54_I	58_L	0.520	0.77
65_F	141_R	0.519	0.77
182_F	380_Y	0.518	0.77
375_V	379_V	0.518	0.77
84_M	90_E	0.517	0.77
295_L	324_L	0.517	0.77
330_G	333_V	0.516	0.77
386_L	393_I	0.516	0.77
503_T	511_T	0.516	0.77
166_N	346_I	0.516	0.77
143_L	309_S	0.515	0.77
459_V	468_F	0.514	0.76
493_R	496_K	0.513	0.76
268_I	359_S	0.513	0.76
127_I	159_Y	0.512	0.76
469_L	472_G	0.512	0.76
406_P	429_L	0.512	0.76
21_L	31_A	0.512	0.76
197_T	200_S	0.511	0.76
8_S	18_A	0.510	0.76
132_I	144_L	0.510	0.76
412_L	417_V	0.509	0.76
66_E	259_T	0.509	0.76
473_S	487_I	0.509	0.76
211_S	215_L	0.508	0.76
299_Y	324_L	0.508	0.76
375_V	378_I	0.507	0.76
152_D	271_F	0.506	0.75
90_E	151_E	0.506	0.75
465_L	471_E	0.506	0.75
498_F	510_Y	0.505	0.75
488_V	498_F	0.505	0.75
299_Y	303_S	0.505	0.75
481_N	484_L	0.505	0.75
215_L	265_F	0.505	0.75
447_L	457_E	0.504	0.75
48_N	53_E	0.502	0.75
398_K	405_S	0.502	0.75
184_A	231_T	0.501	0.75
92_I	168_S	0.501	0.75
69_T	244_I	0.500	0.75
14_T	19_F	0.500	0.75
151_E	155_V	0.500	0.75

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bwzA	2	0.621	100	0.522	Contact Map
4czbA	2	0.626	100	0.538	Contact Map
4cz8A	2	0.6194	100	0.544	Contact Map
1zcdA	1	0.5559	100	0.746	Contact Map
3l9wA	2	0.2905	98.5	0.911	Contact Map
3zuxA	1	0.4992	98.5	0.911	Contact Map
2mdfA	1	0.0935	98.4	0.915	Contact Map
4n7wA	2	0.4975	98.2	0.919	Contact Map
1lnqA	6	0.4608	98.1	0.921	Contact Map
4gx0A	3	0.4942	98	0.923	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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