GREMLIN Database
Q97UN2 - Quinol oxidase-2, rieske iron-sulfur protein-2 (SoxF)
UniProt: Q97UN2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 252 (190)
Sequences: 136 (107)
Seq/√Len: 7.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
142_V196_P4.0990.97
146_C173_C4.0450.97
117_G120_G3.7430.96
145_G173_C3.2650.91
184_G187_V3.0400.87
145_G196_P2.7820.82
138_S196_P2.5610.76
8_L17_A2.4520.73
69_Q72_A2.4230.72
135_Y154_V2.3870.71
82_F136_A2.3760.70
220_S224_P2.3560.70
146_C196_P2.3400.69
117_G124_T2.3320.69
120_G124_T2.3190.68
96_L101_G2.1860.63
219_F222_S2.0630.59
142_V178_Y2.0440.58
16_A19_A1.9810.55
173_C196_P1.9600.55
169_L180_L1.9560.54
96_L103_P1.9150.53
23_L70_Q1.9040.52
90_P96_L1.8820.51
198_I214_T1.8620.51
9_R26_P1.8610.51
90_P200_L1.7920.48
62_I67_D1.7750.47
105_P169_L1.7680.47
48_A51_T1.7650.47
146_C193_R1.7620.47
176_S191_A1.7390.46
70_Q91_C1.6990.44
81_F207_G1.6960.44
57_F62_I1.6900.44
46_L51_T1.6680.43
126_Q132_N1.6580.42
62_I85_P1.6560.42
134_I186_V1.6540.42
170_H188_G1.5750.39
9_R28_A1.5580.39
218_Y221_A1.4540.35
17_A136_A1.4540.35
173_C193_R1.4200.33
18_V66_K1.4060.33
201_E212_I1.3850.32
170_H175_G1.3790.32
178_Y206_T1.3670.32
155_T188_G1.3530.31
221_A225_R1.3370.31
180_L183_G1.3360.31
153_L166_N1.3190.30
9_R13_V1.3160.30
96_L102_Q1.3040.29
99_L102_Q1.3030.29
135_Y180_L1.2900.29
82_F90_P1.2880.29
69_Q73_Q1.2840.29
148_L184_G1.2820.29
145_G193_R1.2740.28
58_P196_P1.2740.28
206_T210_Y1.2650.28
155_T175_G1.2500.28
58_P136_A1.2380.27
175_G178_Y1.2310.27
58_P86_L1.2160.27
4_R169_L1.1990.26
62_I90_P1.1930.26
96_L216_A1.1810.25
175_G215_N1.1780.25
104_V108_P1.1760.25
188_G191_A1.1620.25
96_L105_P1.1450.24
200_L212_I1.1310.24
134_I209_I1.1190.24
141_C171_C1.1020.23
143_H171_C1.1020.23
135_Y184_G1.0870.23
26_P165_T1.0760.22
72_A207_G1.0650.22
191_A220_S1.0630.22
15_G186_V1.0580.22
111_Y148_L1.0530.22
220_S223_I1.0500.22
19_A178_Y1.0320.21
183_G194_P1.0300.21
112_Y203_D1.0270.21
74_S196_P1.0250.21
82_F85_P1.0190.21
48_A91_C1.0190.21
17_A111_Y1.0120.21
176_S203_D1.0020.20
139_D172_P0.9890.20
10_L24_I0.9860.20
175_G188_G0.9820.20
11_Y172_P0.9730.20
146_C175_G0.9690.20
154_V180_L0.9580.19
93_L117_G0.9570.19
136_A195_L0.9500.19
142_V188_G0.9480.19
116_A200_L0.9460.19
216_A220_S0.9420.19
48_A89_E0.9300.19
169_L184_G0.9300.19
155_T170_H0.9300.19
177_L186_V0.9260.18
142_V175_G0.9250.18
72_A79_V0.9210.18
53_G71_Q0.9200.18
101_G204_Q0.9180.18
73_Q136_A0.9130.18
29_D180_L0.9080.18
138_S145_G0.9040.18
18_V108_P0.9040.18
219_F223_I0.9030.18
182_K185_V0.8780.17
62_I84_Y0.8770.17
179_S186_V0.8770.17
221_A224_P0.8680.17
5_R143_H0.8670.17
5_R141_C0.8670.17
5_R171_C0.8670.17
137_F184_G0.8630.17
148_L169_L0.8470.17
153_L193_R0.8440.17
170_H173_C0.8430.17
103_P134_I0.8400.16
68_I164_V0.8340.16
8_L154_V0.8320.16
92_F178_Y0.8300.16
100_L103_P0.8260.16
132_N136_A0.8220.16
145_G174_H0.8180.16
8_L217_P0.8150.16
82_F186_V0.8140.16
132_N199_F0.8120.16
27_L109_N0.8120.16
98_A108_P0.8120.16
19_A148_L0.8060.16
24_I48_A0.7920.15
190_P211_A0.7890.15
63_A69_Q0.7870.15
153_L172_P0.7840.15
62_I216_A0.7770.15
131_N182_K0.7750.15
154_V174_H0.7670.15
82_F200_L0.7640.15
59_K88_N0.7640.15
101_G104_V0.7590.15
63_A68_I0.7570.15
64_N69_Q0.7540.15
8_L184_G0.7510.15
139_D155_T0.7460.14
6_T204_Q0.7400.14
12_L193_R0.7360.14
134_I184_G0.7340.14
23_L59_K0.7320.14
108_P177_L0.7310.14
147_Q178_Y0.7300.14
28_A137_F0.7250.14
202_Y206_T0.7240.14
179_S209_I0.7230.14
134_I167_S0.7230.14
146_C174_H0.7210.14
155_T164_V0.7200.14
81_F108_P0.7190.14
105_P164_V0.7180.14
8_L96_L0.7170.14
59_K87_T0.7170.14
74_S77_C0.7160.14
191_A219_F0.7140.14
186_V194_P0.7140.14
149_P183_G0.7120.14
145_G172_P0.7060.14
86_L146_C0.7040.14
23_L26_P0.7020.14
86_L90_P0.7000.14
176_S200_L0.7000.14
86_L89_E0.6970.14
97_Q103_P0.6950.14
90_P102_Q0.6950.14
177_L188_G0.6940.13
153_L170_H0.6920.13
24_I28_A0.6910.13
170_H193_R0.6910.13
147_Q211_A0.6900.13
59_K213_G0.6870.13
133_S167_S0.6860.13
13_V52_D0.6800.13
58_P173_C0.6800.13
81_F88_N0.6780.13
7_F17_A0.6750.13
10_L61_R0.6740.13
103_P107_I0.6720.13
183_G213_G0.6690.13
178_Y221_A0.6630.13
142_V173_C0.6620.13
172_P193_R0.6620.13
112_Y118_P0.6600.13
74_S78_P0.6520.13
173_C190_P0.6500.13
22_P187_V0.6490.13
149_P175_G0.6490.13
172_P223_I0.6440.13
144_L169_L0.6430.13
82_F94_V0.6430.13
3_N93_L0.6370.12
62_I69_Q0.6350.12
139_D178_Y0.6340.12
178_Y188_G0.6290.12
13_V200_L0.6280.12
62_I71_Q0.6250.12
92_F139_D0.6240.12
16_A212_I0.6230.12
219_F225_R0.6200.12
69_Q85_P0.6190.12
84_Y183_G0.6190.12
75_S78_P0.6150.12
149_P214_T0.6120.12
116_A216_A0.6060.12
61_R67_D0.6040.12
143_H195_L0.6040.12
141_C195_L0.6040.12
171_C195_L0.6040.12
85_P89_E0.6030.12
53_G87_T0.6020.12
107_I112_Y0.5970.12
54_L58_P0.5950.12
142_V155_T0.5900.12
147_Q202_Y0.5890.12
95_D98_A0.5860.12
186_V189_G0.5830.12
172_P207_G0.5810.12
110_P204_Q0.5790.11
174_H196_P0.5750.11
93_L96_L0.5720.11
141_C189_G0.5720.11
143_H189_G0.5720.11
171_C189_G0.5720.11
84_Y210_Y0.5710.11
78_P82_F0.5680.11
145_G175_G0.5680.11
103_P209_I0.5670.11
144_L149_P0.5640.11
154_V184_G0.5620.11
202_Y209_I0.5540.11
85_P183_G0.5500.11
110_P123_K0.5480.11
148_L180_L0.5480.11
13_V29_D0.5470.11
145_G188_G0.5460.11
166_N172_P0.5450.11
84_Y90_P0.5410.11
53_G123_K0.5400.11
187_V213_G0.5390.11
178_Y191_A0.5390.11
85_P135_Y0.5380.11
6_T182_K0.5360.11
155_T178_Y0.5360.11
86_L173_C0.5360.11
16_A70_Q0.5350.11
142_V198_I0.5320.11
74_S85_P0.5310.11
14_V18_V0.5290.11
135_Y216_A0.5260.11
13_V28_A0.5250.11
74_S185_V0.5240.11
57_F67_D0.5240.11
188_G214_T0.5210.11
192_P213_G0.5190.11
171_C190_P0.5150.10
143_H190_P0.5150.10
141_C190_P0.5150.10
222_S225_R0.5080.10
132_N164_V0.5070.10
24_I66_K0.5060.10
84_Y91_C0.5050.10
7_F89_E0.5040.10
45_Y93_L0.5040.10
154_V193_R0.5040.10
184_G209_I0.5020.10
144_L167_S0.5020.10
111_Y180_L0.5010.10
56_G212_I0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1jm1A 1 0.7619 100 0.599 Contact Map
4aayB 1 0.5238 100 0.668 Contact Map
4ogqD 1 0.6389 99.9 0.741 Contact Map
2qjyC 2 0.6746 99.8 0.76 Contact Map
3cx5E 1 0.6468 99.8 0.766 Contact Map
4d6tE 1 0.1667 99.8 0.773 Contact Map
1nykA 1 0.5913 99.8 0.774 Contact Map
1pp9E 1 0.6508 99.8 0.775 Contact Map
1g8kB 1 0.5278 99.7 0.788 Contact Map
1rieA 1 0.5 99.5 0.819 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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