GREMLIN Database
Q97UK7 - Glycosyltransferase, putative
UniProt: Q97UK7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 470 (375)
Sequences: 7628 (5297)
Seq/√Len: 273.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
216_T220_K4.4441.00
73_D101_P4.1881.00
137_Y156_S3.8521.00
88_D153_D3.7631.00
397_L400_K3.6181.00
66_L94_V3.6031.00
397_L402_I3.2621.00
218_V255_Y3.1601.00
139_L213_L3.0431.00
64_T135_T2.9591.00
103_K107_I2.9541.00
221_S253_K2.8571.00
137_Y159_L2.7431.00
67_I84_V2.6431.00
162_D256_K2.5861.00
178_K181_F2.5171.00
154_I262_D2.4451.00
163_I258_T2.3981.00
158_K260_T2.3751.00
94_V129_G2.2341.00
150_N154_I2.1921.00
95_G115_K2.1831.00
155_L213_L2.1801.00
104_S108_S2.1411.00
161_G256_K2.1411.00
279_Q283_W2.1391.00
137_Y213_L2.1361.00
217_D221_S2.1291.00
165_A257_A2.0591.00
272_T275_D2.0501.00
63_I156_S1.9971.00
350_D353_R1.9851.00
380_H383_P1.9681.00
64_T133_V1.9581.00
300_I304_G1.9511.00
397_L403_L1.9351.00
221_S255_Y1.9251.00
164_V255_Y1.8731.00
101_P104_S1.8711.00
110_G116_L1.8621.00
102_Y106_T1.7791.00
34_F38_Y1.7691.00
39_I42_T1.7541.00
298_G304_G1.7471.00
32_S36_I1.7461.00
399_A402_I1.7401.00
24_Y28_S1.7271.00
300_I303_K1.7171.00
62_E136_P1.7081.00
345_R349_T1.7041.00
388_P391_L1.6981.00
310_T314_W1.6971.00
387_N391_L1.6861.00
78_K82_N1.6691.00
383_P386_F1.6671.00
397_L404_F1.6481.00
400_K403_L1.6421.00
62_E134_K1.6241.00
384_H387_N1.6231.00
137_Y215_K1.6021.00
218_V250_I1.6001.00
129_G133_V1.5611.00
245_Q249_Y1.5601.00
63_I152_I1.5471.00
139_L152_I1.5431.00
106_T113_F1.5331.00
346_A353_R1.5301.00
314_W317_L1.5131.00
174_P181_F1.5121.00
391_L394_D1.5061.00
330_E334_S1.5041.00
95_G98_C1.4931.00
36_I40_S1.4861.00
382_L385_H1.4841.00
159_L213_L1.4811.00
64_T92_V1.4811.00
207_L212_I1.4671.00
380_H384_H1.4631.00
133_V216_T1.4611.00
349_T353_R1.4571.00
346_A350_D1.4571.00
35_T39_I1.4571.00
381_F384_H1.4541.00
329_T333_L1.4371.00
78_K108_S1.4311.00
310_T313_Y1.4251.00
145_T265_V1.4231.00
388_P392_I1.4221.00
192_E198_L1.4171.00
195_Y198_L1.4121.00
241_G286_S1.4101.00
377_K380_H1.3931.00
110_G115_K1.3891.00
286_S289_F1.3891.00
71_K98_C1.3791.00
385_H388_P1.3691.00
376_N379_H1.3651.00
397_L401_M1.3631.00
380_H391_L1.3521.00
62_E135_T1.3421.00
379_H383_P1.3371.00
211_C265_V1.3301.00
400_K404_F1.3221.00
349_T352_A1.3161.00
387_N394_D1.3031.00
187_M280_M1.2981.00
345_R353_R1.2911.00
64_T216_T1.2851.00
34_F42_T1.2851.00
387_N392_I1.2841.00
345_R348_T1.2791.00
28_S32_S1.2711.00
83_S147_L1.2661.00
342_F346_A1.2641.00
164_V250_I1.2601.00
381_F385_H1.2571.00
327_L330_E1.2501.00
380_H387_N1.2471.00
28_S31_I1.2471.00
36_I39_I1.2441.00
327_L332_I1.2371.00
341_N345_R1.2361.00
377_K381_F1.2341.00
89_L156_S1.2341.00
368_N371_P1.2221.00
104_S107_I1.2221.00
384_H388_P1.2131.00
380_H385_H1.2071.00
399_A403_L1.2001.00
348_T352_A1.1971.00
38_Y42_T1.1971.00
92_V112_L1.1971.00
155_L168_P1.1961.00
318_P323_L1.1961.00
165_A250_I1.1961.00
106_T109_K1.1921.00
331_I334_S1.1891.00
348_T353_R1.1871.00
69_V77_F1.1821.00
172_I269_A1.1801.00
93_V96_D1.1761.00
105_I109_K1.1721.00
164_V218_V1.1661.00
299_T303_K1.1621.00
32_S35_T1.1581.00
87_Q152_I1.1481.00
194_S198_L1.1451.00
138_V219_I1.1451.00
31_I34_F1.1421.00
43_L46_A1.1361.00
317_L321_T1.1351.00
57_N60_R1.1351.00
166_V260_T1.1311.00
350_D354_F1.1291.00
370_D374_I1.1271.00
384_H391_L1.1261.00
28_S35_T1.1201.00
314_W318_P1.1191.00
25_L28_S1.1161.00
317_L320_L1.1151.00
388_P395_N1.1081.00
378_F381_F1.1061.00
97_G100_E1.1041.00
192_E196_R1.1031.00
60_R90_N1.0931.00
154_I157_S1.0881.00
227_E230_S1.0861.00
105_I108_S1.0851.00
38_Y41_F1.0851.00
308_M314_W1.0831.00
251_Y257_A1.0811.00
377_K384_H1.0801.00
130_F138_V1.0731.00
116_L124_R1.0691.00
123_R127_R1.0651.00
22_T26_L1.0611.00
114_V128_E1.0581.00
379_H382_L1.0541.00
65_V139_L1.0501.00
192_E197_A1.0441.00
309_F313_Y1.0411.00
94_V125_A1.0401.00
396_K403_L1.0351.00
107_I115_K1.0311.00
193_I197_A1.0291.00
192_E195_Y1.0281.00
397_L405_H1.0281.00
353_R357_N1.0261.00
188_Q191_R1.0241.00
392_I395_N1.0241.00
31_I35_T1.0231.00
101_P105_I1.0231.00
389_I392_I1.0171.00
329_T335_H1.0171.00
35_T42_T1.0101.00
329_T334_S1.0071.00
27_I31_I1.0061.00
327_L331_I1.0061.00
387_N390_M1.0051.00
155_L166_V1.0011.00
65_V87_Q1.0011.00
367_F371_P1.0001.00
103_K106_T0.9891.00
401_M404_F0.9851.00
29_S32_S0.9851.00
370_D373_P0.9751.00
349_T357_N0.9721.00
351_P354_F0.9711.00
24_Y32_S0.9621.00
362_R366_L0.9581.00
310_T318_P0.9581.00
379_H386_F0.9521.00
276_L280_M0.9461.00
46_A49_Y0.9391.00
126_I140_L0.9391.00
390_M394_D0.9381.00
114_V132_Y0.9361.00
42_T46_A0.9341.00
401_M405_H0.9311.00
122_K126_I0.9301.00
83_S146_I0.9291.00
21_F24_Y0.9211.00
379_H391_L0.9201.00
363_I366_L0.9201.00
29_S33_I0.9191.00
368_N372_T0.9181.00
350_D357_N0.9091.00
84_V141_L0.9071.00
165_A207_L0.9061.00
84_V147_L0.9041.00
25_L32_S0.9021.00
93_V106_T0.9021.00
32_S39_I0.9001.00
20_D24_Y0.8901.00
388_P394_D0.8891.00
391_L395_N0.8891.00
368_N373_P0.8881.00
56_T59_K0.8881.00
298_G303_K0.8871.00
170_I210_Q0.8861.00
386_F389_I0.8861.00
128_E132_Y0.8851.00
44_P47_F0.8821.00
24_Y35_T0.8811.00
242_D286_S0.8811.00
368_N376_N0.8711.00
400_K405_H0.8701.00
23_L27_I0.8681.00
381_F388_P0.8631.00
297_D304_G0.8631.00
396_K400_K0.8631.00
37_L45_L0.8621.00
336_A339_H0.8621.00
301_I304_G0.8611.00
61_S156_S0.8601.00
117_D121_G0.8591.00
318_P322_L0.8541.00
42_T45_L0.8531.00
318_P321_T0.8531.00
126_I228_F0.8501.00
148_P266_K0.8471.00
345_R352_A0.8471.00
79_E82_N0.8461.00
35_T38_Y0.8461.00
145_T267_T0.8441.00
396_K402_I0.8421.00
328_Y331_I0.8411.00
390_M393_Y0.8351.00
24_Y38_Y0.8311.00
127_R130_F0.8260.99
290_F294_E0.8260.99
310_T317_L0.8240.99
22_T35_T0.8240.99
158_K258_T0.8220.99
299_T304_G0.8190.99
376_N383_P0.8180.99
298_G302_K0.8180.99
123_R126_I0.8150.99
116_L128_E0.8130.99
141_L147_L0.8110.99
373_P377_K0.8110.99
210_Q267_T0.8100.99
349_T356_E0.8100.99
40_S44_P0.8080.99
100_E104_S0.8080.99
84_V91_F0.8080.99
380_H386_F0.8080.99
193_I198_L0.8070.99
327_L334_S0.8060.99
215_K255_Y0.8040.99
83_S87_Q0.8020.99
383_P387_N0.8000.99
376_N387_N0.8000.99
170_I267_T0.7990.99
31_I42_T0.7980.99
389_I394_D0.7980.99
193_I196_R0.7960.99
184_S187_M0.7940.99
82_N109_K0.7940.99
398_S404_F0.7930.99
78_K105_I0.7900.99
80_V83_S0.7890.99
40_S43_L0.7850.99
118_K121_G0.7830.99
189_R192_E0.7820.99
384_H395_N0.7820.99
138_V216_T0.7810.99
329_T332_I0.7810.99
343_I347_I0.7800.99
102_Y105_I0.7800.99
385_H391_L0.7800.99
33_I36_I0.7790.99
184_S188_Q0.7780.99
352_A356_E0.7780.99
369_I376_N0.7760.99
33_I37_L0.7750.99
357_N361_S0.7730.99
296_G299_T0.7730.99
145_T210_Q0.7720.99
100_E103_K0.7690.99
387_N395_N0.7690.99
217_D220_K0.7690.99
188_Q192_E0.7680.99
301_I305_F0.7600.99
128_E131_K0.7590.99
147_L151_S0.7590.99
241_G244_R0.7580.99
313_Y318_P0.7580.99
385_H389_I0.7580.99
295_I300_I0.7550.99
25_L29_S0.7530.99
317_L322_L0.7500.99
45_L50_K0.7490.99
372_T376_N0.7490.99
337_I340_W0.7450.99
386_F390_M0.7430.99
399_A404_F0.7420.99
276_L279_Q0.7420.99
382_L391_L0.7400.99
239_I245_Q0.7390.99
326_S333_L0.7360.99
377_K385_H0.7340.99
28_S42_T0.7330.99
314_W321_T0.7280.99
321_T324_S0.7270.99
379_H387_N0.7260.99
342_F353_R0.7250.99
72_E143_S0.7220.99
357_N360_I0.7190.99
30_L35_T0.7180.99
114_V129_G0.7180.99
330_E336_A0.7170.99
303_K307_Y0.7160.99
341_N349_T0.7160.99
347_I353_R0.7150.98
307_Y310_T0.7150.98
61_S135_T0.7140.98
270_P283_W0.7120.98
379_H385_H0.7110.98
295_I298_G0.7100.98
60_R153_D0.7070.98
342_F349_T0.7040.98
191_R195_Y0.7010.98
92_V114_V0.7010.98
308_M313_Y0.7010.98
39_I43_L0.7000.98
26_L29_S0.6980.98
314_W320_L0.6980.98
116_L125_A0.6970.98
319_L322_L0.6930.98
139_L155_L0.6930.98
222_L250_I0.6910.98
381_F386_F0.6900.98
32_S42_T0.6890.98
94_V97_G0.6880.98
386_F391_L0.6860.98
31_I37_L0.6860.98
219_I279_Q0.6840.98
25_L36_I0.6840.98
31_I38_Y0.6820.98
379_H394_D0.6810.98
164_V215_K0.6810.98
308_M312_L0.6810.98
88_D150_N0.6810.98
378_F384_H0.6800.98
385_H394_D0.6800.98
313_Y319_L0.6800.98
376_N380_H0.6780.98
367_F370_D0.6780.98
267_T279_Q0.6760.98
96_D116_L0.6760.98
344_V347_I0.6740.98
380_H390_M0.6730.98
158_K166_V0.6720.98
33_I42_T0.6720.98
206_S244_R0.6710.98
77_F81_I0.6710.98
44_P49_Y0.6690.98
151_S211_C0.6630.98
387_N393_Y0.6620.98
139_L151_S0.6590.97
377_K383_P0.6550.97
384_H394_D0.6550.97
311_V315_Y0.6550.97
140_L167_S0.6530.97
29_S39_I0.6520.97
373_P376_N0.6520.97
376_N381_F0.6520.97
335_H338_K0.6510.97
341_N348_T0.6500.97
122_K209_G0.6460.97
33_I39_I0.6460.97
84_V87_Q0.6450.97
135_T216_T0.6450.97
317_L323_L0.6440.97
297_D303_K0.6440.97
65_V152_I0.6430.97
348_T357_N0.6410.97
369_I372_T0.6390.97
34_F37_L0.6380.97
328_Y334_S0.6370.97
352_A358_V0.6360.97
136_P217_D0.6360.97
61_S89_L0.6350.97
299_T302_K0.6340.97
345_R350_D0.6330.97
297_D302_K0.6290.97
247_T257_A0.6290.97
157_S160_A0.6280.97
21_F31_I0.6270.97
396_K404_F0.6270.97
346_A349_T0.6260.97
348_T354_F0.6250.97
298_G301_I0.6240.96
206_S247_T0.6240.96
123_R242_D0.6240.96
22_T28_S0.6230.96
163_I166_V0.6220.96
390_M395_N0.6210.96
319_L323_L0.6210.96
306_F310_T0.6210.96
37_L46_A0.6210.96
199_A258_T0.6180.96
347_I351_P0.6180.96
368_N374_I0.6160.96
25_L43_L0.6150.96
163_I256_K0.6150.96
396_K405_H0.6140.96
25_L31_I0.6120.96
348_T351_P0.6120.96
45_L48_T0.6080.96
38_Y46_A0.6050.96
24_Y27_I0.6050.96
385_H393_Y0.6050.96
112_L115_K0.6040.96
240_L286_S0.6040.96
45_L49_Y0.6020.96
173_L268_K0.6010.96
371_P374_I0.5990.96
26_L35_T0.5980.96
177_N271_D0.5980.96
161_G258_T0.5970.95
29_S42_T0.5970.95
313_Y316_A0.5920.95
378_F382_L0.5920.95
398_S403_L0.5910.95
317_L324_S0.5890.95
398_S402_I0.5870.95
353_R358_V0.5860.95
112_L116_L0.5850.95
341_N353_R0.5820.95
333_L338_K0.5810.95
102_Y107_I0.5810.95
316_A320_L0.5810.95
86_K149_D0.5810.95
371_P375_A0.5800.95
312_L316_A0.5800.95
29_S36_I0.5800.95
380_H395_N0.5790.95
379_H388_P0.5780.95
383_P393_Y0.5770.95
127_R131_K0.5740.94
383_P394_D0.5740.94
87_Q151_S0.5710.94
95_G103_K0.5690.94
38_Y45_L0.5650.94
125_A129_G0.5640.94
369_I379_H0.5640.94
30_L33_I0.5630.94
29_S35_T0.5620.94
122_K142_D0.5610.94
71_K100_E0.5590.94
71_K99_D0.5590.94
188_Q196_R0.5580.94
130_F140_L0.5570.94
372_T377_K0.5560.93
380_H388_P0.5550.93
356_E361_S0.5530.93
370_D376_N0.5530.93
396_K399_A0.5530.93
111_G114_V0.5510.93
103_K115_K0.5500.93
321_T325_Y0.5500.93
92_V96_D0.5490.93
362_R365_R0.5490.93
379_H384_H0.5490.93
347_I350_D0.5470.93
152_I213_L0.5450.93
375_A378_F0.5450.93
31_I43_L0.5440.93
385_H390_M0.5400.92
184_S269_A0.5400.92
250_I255_Y0.5390.92
341_N347_I0.5380.92
146_I173_L0.5380.92
46_A50_K0.5380.92
26_L30_L0.5370.92
169_E259_V0.5360.92
369_I373_P0.5360.92
209_G282_R0.5350.92
24_Y39_I0.5330.92
28_S33_I0.5330.92
398_S405_H0.5330.92
223_V227_E0.5320.92
371_P377_K0.5320.92
342_F350_D0.5320.92
370_D375_A0.5320.92
332_I336_A0.5310.92
385_H395_N0.5280.92
37_L42_T0.5250.91
378_F387_N0.5250.91
279_Q282_R0.5220.91
29_S38_Y0.5200.91
95_G144_D0.5200.91
37_L41_F0.5200.91
92_V95_G0.5200.91
96_D99_D0.5190.91
385_H392_I0.5190.91
396_K401_M0.5150.91
227_E231_V0.5150.91
62_E90_N0.5140.91
32_S43_L0.5130.90
210_Q279_Q0.5130.90
122_K286_S0.5110.90
377_K388_P0.5100.90
29_S46_A0.5100.90
374_I378_F0.5100.90
367_F372_T0.5100.90
36_I42_T0.5090.90
27_I43_L0.5090.90
383_P388_P0.5090.90
28_S38_Y0.5080.90
167_S267_T0.5080.90
140_L212_I0.5080.90
151_S155_L0.5070.90
228_F231_V0.5070.90
378_F395_N0.5060.90
24_Y33_I0.5060.90
87_Q147_L0.5050.90
361_S364_D0.5040.90
356_E359_I0.5040.90
196_R210_Q0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p02A 1 0.966 100 0.389 Contact Map
2z86A 2 0.6149 100 0.639 Contact Map
1qg8A 1 0.4426 100 0.659 Contact Map
3bcvA 2 0.3681 100 0.662 Contact Map
1xhbA 1 0.8064 100 0.685 Contact Map
3ckjA 2 0.5872 100 0.685 Contact Map
2nxvA 4 0.5043 100 0.69 Contact Map
2bo4A 4 0.6787 100 0.691 Contact Map
3l7iA 4 0.1085 100 0.692 Contact Map
2d7iA 1 0.7106 100 0.694 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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