Q97UI1 - SULSO - GREMLIN Contacts

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Q97UI1 - Beta-glucuronidase (GusB)

UniProt:	Q97UI1	Sequences: MRSFYRPKIDLQGFWKFKIDNENTGEENGWYKGLESEDIIYVPASWNEQNPKWDQFSGIAWYQKDLFVSNDNGNRKAWMVFEGAGYITKLWINGEYGGTHEGSFTQFKFPIKLKVNEFNKIVVKIDNTPSPYNLPPARDLNNAAFDFFNYGGIHRPVYIEFVDECHVEDITVYTKSYGHLKVEILSECNQRFSLRFKLVDKEGRVILNEESSNEVFEKDVNNVIPWSPDNPYLYTLIVEMYVGGNLKDSVYERIGFRDVEVKDGKIYLNGKPIFLKGFGRHEDFPILGKFTYGAVLVRDFYLMRKIGANSFRTSHYPYSNEHLDLADEMGFLVILEPPLCYSNISRVMSQEEIAKMFGDVKYFEKVRDTIKEMIRQHKNRPSVIMYSVMNEPPSDIREVAEFIRREVELFKSLDSSRPVTFASHRSVRDLALEYVDVISLNYYHGWYTEWGDIDSGVKVVAIELEEIHKKFPEKPIIITEFGADAIYGLHSDPPQMWSEEYQSEMIRKYIEALREKDYIVGFHIWNFADFRTPQNPSRTILNRKGIFTRDRQPKLAAKVVEELFKNKLRS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	570 (510)
Sequences:	8187 (6248)
Seq/√Len:	276.7

ECOLI - BGLR BGA2 BGAL
SULSO - Q97UI1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
65_D	118_F	4.435	1.00
98_G	109_F	4.002	1.00
253_R	328_E	3.890	1.00
89_K	96_Y	3.710	1.00
12_Q	156_P	3.504	1.00
93_N	119_N	3.465	1.00
76_K	110_P	3.302	1.00
67_F	118_F	3.104	1.00
97_G	114_K	3.092	1.00
92_I	121_I	3.085	1.00
297_V	328_E	3.013	1.00
224_I	232_Y	3.010	1.00
195_R	239_E	2.957	1.00
195_R	241_Y	2.927	1.00
16_K	39_I	2.900	1.00
63_Q	120_K	2.879	1.00
241_Y	246_L	2.866	1.00
199_V	237_I	2.726	1.00
197_K	239_E	2.725	1.00
310_S	523_H	2.677	1.00
81_F	123_V	2.655	1.00
375_R	413_L	2.613	1.00
92_I	97_G	2.595	1.00
293_G	321_E	2.576	1.00
224_I	230_N	2.496	1.00
414_D	417_R	2.439	1.00
84_A	153_I	2.433	1.00
301_Y	305_K	2.428	1.00
84_A	88_T	2.375	1.00
75_R	161_F	2.337	1.00
297_V	301_Y	2.311	1.00
239_E	249_S	2.286	1.00
183_E	215_V	2.268	1.00
82_E	158_Y	2.256	1.00
95_E	114_K	2.214	1.00
89_K	99_T	2.181	1.00
77_A	161_F	2.166	1.00
197_K	237_I	2.132	1.00
262_K	267_Y	2.128	1.00
84_A	125_I	2.124	1.00
374_I	410_F	2.119	1.00
171_T	378_K	2.105	1.00
235_T	251_Y	2.102	1.00
239_E	246_L	2.097	1.00
198_L	254_I	2.092	1.00
404_R	408_E	2.050	1.00
63_Q	122_V	2.032	1.00
65_D	120_K	2.031	1.00
227_S	271_K	2.023	1.00
237_I	251_Y	2.023	1.00
96_Y	99_T	2.006	1.00
237_I	249_S	1.997	1.00
75_R	163_D	1.991	1.00
300_F	329_M	1.983	1.00
311_F	331_F	1.981	1.00
181_K	217_E	1.971	1.00
227_S	230_N	1.968	1.00
16_K	63_Q	1.960	1.00
201_K	232_Y	1.950	1.00
235_T	253_R	1.928	1.00
301_Y	329_M	1.860	1.00
220_V	256_F	1.857	1.00
220_V	223_V	1.846	1.00
72_N	161_F	1.846	1.00
77_A	115_V	1.838	1.00
548_T	552_Q	1.827	1.00
332_L	384_I	1.822	1.00
385_M	437_V	1.822	1.00
89_K	124_K	1.821	1.00
367_R	405_R	1.814	1.00
228_P	332_L	1.811	1.00
14_F	39_I	1.801	1.00
196_F	238_V	1.796	1.00
170_I	238_V	1.787	1.00
260_E	267_Y	1.781	1.00
78_W	110_P	1.772	1.00
409_L	413_L	1.772	1.00
179_H	217_E	1.765	1.00
199_V	205_V	1.739	1.00
407_V	411_K	1.724	1.00
371_K	409_L	1.723	1.00
306_I	557_A	1.722	1.00
326_A	333_V	1.699	1.00
300_F	326_A	1.697	1.00
205_V	208_N	1.691	1.00
300_F	331_F	1.687	1.00
44_A	49_Q	1.683	1.00
34_L	63_Q	1.674	1.00
236_L	254_I	1.666	1.00
293_G	297_V	1.665	1.00
61_W	122_V	1.651	1.00
200_D	204_R	1.643	1.00
178_G	256_F	1.637	1.00
8_K	158_Y	1.633	1.00
168_E	187_E	1.628	1.00
80_V	160_E	1.628	1.00
408_E	412_S	1.627	1.00
521_G	525_W	1.625	1.00
327_D	380_R	1.623	1.00
181_K	215_V	1.620	1.00
81_F	157_V	1.604	1.00
81_F	84_A	1.596	1.00
258_D	270_G	1.595	1.00
507_R	511_E	1.595	1.00
61_W	124_K	1.593	1.00
80_V	108_K	1.578	1.00
106_Q	376_Q	1.576	1.00
69_S	72_N	1.575	1.00
78_W	108_K	1.571	1.00
11_L	66_L	1.549	1.00
371_K	413_L	1.546	1.00
183_E	213_N	1.543	1.00
76_K	164_E	1.537	1.00
92_I	111_I	1.533	1.00
91_W	96_Y	1.528	1.00
375_R	378_K	1.517	1.00
196_F	236_L	1.495	1.00
327_D	382_S	1.488	1.00
100_H	107_F	1.485	1.00
261_V	418_P	1.483	1.00
68_V	115_V	1.477	1.00
253_R	324_D	1.477	1.00
275_L	384_I	1.476	1.00
66_L	119_N	1.474	1.00
268_L	332_L	1.471	1.00
78_W	162_V	1.463	1.00
175_K	181_K	1.462	1.00
79_M	111_I	1.458	1.00
325_L	329_M	1.457	1.00
59_I	124_K	1.457	1.00
325_L	328_E	1.453	1.00
80_V	158_Y	1.447	1.00
278_F	308_A	1.445	1.00
409_L	412_S	1.445	1.00
411_K	419_V	1.438	1.00
76_K	113_L	1.431	1.00
72_N	77_A	1.416	1.00
299_D	551_R	1.415	1.00
284_F	295_V	1.407	1.00
297_V	329_M	1.401	1.00
165_C	188_C	1.399	1.00
297_V	325_L	1.393	1.00
370_I	410_F	1.386	1.00
311_F	322_H	1.385	1.00
228_P	268_L	1.379	1.00
367_R	409_L	1.367	1.00
371_K	412_S	1.365	1.00
233_L	253_R	1.359	1.00
10_D	156_P	1.357	1.00
167_V	184_I	1.357	1.00
173_Y	416_S	1.355	1.00
16_K	34_L	1.350	1.00
197_K	205_V	1.342	1.00
179_H	219_D	1.336	1.00
193_S	210_E	1.327	1.00
259_V	384_I	1.324	1.00
298_R	301_Y	1.324	1.00
66_L	121_I	1.322	1.00
169_D	378_K	1.320	1.00
76_K	112_K	1.317	1.00
196_F	216_F	1.313	1.00
46_W	60_A	1.309	1.00
553_P	557_A	1.308	1.00
223_V	256_F	1.299	1.00
174_T	256_F	1.293	1.00
123_V	153_I	1.289	1.00
168_E	185_L	1.287	1.00
268_L	273_I	1.284	1.00
38_D	49_Q	1.281	1.00
246_L	249_S	1.281	1.00
292_Y	295_V	1.276	1.00
79_M	90_L	1.269	1.00
368_D	372_E	1.263	1.00
304_R	329_M	1.261	1.00
165_C	192_F	1.257	1.00
198_L	236_L	1.256	1.00
193_S	241_Y	1.254	1.00
173_Y	183_E	1.248	1.00
40_I	49_Q	1.248	1.00
335_L	377_H	1.228	1.00
177_Y	219_D	1.227	1.00
97_G	109_F	1.224	1.00
78_W	166_H	1.216	1.00
190_Q	242_V	1.205	1.00
199_V	235_T	1.199	1.00
195_R	208_N	1.198	1.00
74_N	164_E	1.195	1.00
259_V	266_I	1.194	1.00
371_K	375_R	1.191	1.00
105_T	372_E	1.187	1.00
294_A	297_V	1.186	1.00
84_A	90_L	1.182	1.00
172_V	236_L	1.182	1.00
175_K	258_D	1.181	1.00
90_L	123_V	1.181	1.00
101_E	365_K	1.180	1.00
321_E	325_L	1.175	1.00
370_I	406_E	1.168	1.00
303_M	331_F	1.165	1.00
242_V	247_K	1.162	1.00
229_D	273_I	1.161	1.00
185_L	213_N	1.150	1.00
229_D	304_R	1.144	1.00
335_L	373_M	1.138	1.00
367_R	371_K	1.131	1.00
228_P	273_I	1.126	1.00
92_I	114_K	1.125	1.00
207_L	218_K	1.122	1.00
318_Y	323_L	1.120	1.00
88_T	123_V	1.118	1.00
59_I	126_D	1.118	1.00
229_D	271_K	1.112	1.00
388_V	410_F	1.109	1.00
172_V	254_I	1.108	1.00
287_L	290_F	1.107	1.00
280_R	318_Y	1.097	1.00
167_V	238_V	1.095	1.00
25_G	30_W	1.094	1.00
180_L	256_F	1.089	1.00
116_N	119_N	1.083	1.00
303_M	311_F	1.082	1.00
195_R	210_E	1.082	1.00
111_I	115_V	1.080	1.00
197_K	208_N	1.079	1.00
287_L	292_Y	1.078	1.00
172_V	252_E	1.075	1.00
70_N	117_E	1.075	1.00
303_M	308_A	1.072	1.00
386_Y	414_D	1.064	1.00
34_L	37_E	1.062	1.00
192_F	240_M	1.062	1.00
264_G	267_Y	1.061	1.00
265_K	272_P	1.060	1.00
508_K	512_A	1.060	1.00
33_G	36_S	1.057	1.00
87_I	101_E	1.056	1.00
517_D	521_G	1.056	1.00
7_P	75_R	1.056	1.00
275_L	310_S	1.052	1.00
364_E	368_D	1.049	1.00
14_F	41_Y	1.046	1.00
200_D	224_I	1.042	1.00
300_F	325_L	1.042	1.00
203_G	206_I	1.041	1.00
267_Y	272_P	1.041	1.00
70_N	73_G	1.041	1.00
91_W	124_K	1.040	1.00
323_L	335_L	1.035	1.00
169_D	375_R	1.033	1.00
40_I	44_A	1.033	1.00
83_G	155_R	1.031	1.00
94_G	122_V	1.031	1.00
407_V	419_V	1.028	1.00
273_I	332_L	1.026	1.00
76_K	166_H	1.012	1.00
167_V	240_M	1.008	1.00
17_F	60_A	1.005	1.00
502_Q	505_M	1.001	1.00
100_H	372_E	1.000	1.00
322_H	333_V	0.999	1.00
293_G	324_D	0.997	1.00
287_L	295_V	0.995	1.00
41_Y	49_Q	0.994	1.00
323_L	377_H	0.993	1.00
260_E	270_G	0.992	1.00
298_R	302_L	0.987	1.00
321_E	324_D	0.985	1.00
323_L	380_R	0.982	1.00
560_V	564_F	0.981	1.00
174_T	178_G	0.979	1.00
241_Y	247_K	0.976	1.00
185_L	375_R	0.975	1.00
37_E	63_Q	0.972	1.00
323_L	333_V	0.971	1.00
374_I	409_L	0.971	1.00
180_L	254_I	0.969	1.00
200_D	206_I	0.969	1.00
334_I	385_M	0.966	1.00
302_L	305_K	0.965	1.00
91_W	122_V	0.962	1.00
240_M	247_K	0.960	1.00
322_H	326_A	0.957	1.00
201_K	224_I	0.957	1.00
266_I	384_I	0.957	1.00
293_G	325_L	0.953	1.00
360_V	364_E	0.953	1.00
83_G	154_H	0.950	1.00
84_A	123_V	0.949	1.00
9_I	161_F	0.948	1.00
374_I	413_L	0.941	1.00
61_W	91_W	0.932	1.00
363_F	405_R	0.931	1.00
199_V	203_G	0.930	1.00
306_I	558_K	0.929	1.00
47_N	151_G	0.928	1.00
558_K	561_E	0.926	1.00
66_L	93_N	0.921	1.00
108_K	160_E	0.918	1.00
200_D	232_Y	0.916	1.00
303_M	527_F	0.915	1.00
106_Q	372_E	0.911	1.00
335_L	383_V	0.902	1.00
302_L	547_F	0.901	1.00
79_M	121_I	0.898	1.00
526_N	530_F	0.898	1.00
16_K	65_D	0.897	1.00
20_D	25_G	0.897	1.00
518_Y	521_G	0.895	1.00
368_D	371_K	0.893	1.00
184_I	214_E	0.892	1.00
171_T	183_E	0.889	1.00
100_H	105_T	0.888	1.00
562_E	565_K	0.886	1.00
477_I	480_E	0.885	1.00
20_D	61_W	0.885	1.00
178_G	223_V	0.884	1.00
294_A	301_Y	0.883	1.00
386_Y	417_R	0.882	1.00
26_E	124_K	0.881	1.00
280_R	299_D	0.881	1.00
262_K	265_K	0.881	1.00
95_E	113_L	0.879	1.00
111_I	159_I	0.877	1.00
45_S	48_E	0.874	1.00
176_S	258_D	0.870	1.00
87_I	99_T	0.869	1.00
194_L	238_V	0.866	1.00
284_F	292_Y	0.862	1.00
166_H	187_E	0.861	1.00
324_D	328_E	0.860	1.00
170_I	252_E	0.859	1.00
333_V	382_S	0.858	1.00
302_L	553_P	0.856	1.00
115_V	119_N	0.855	1.00
41_Y	44_A	0.855	1.00
184_I	216_F	0.852	1.00
84_A	107_F	0.852	1.00
11_L	64_K	0.852	1.00
466_E	470_K	0.851	1.00
243_G	246_L	0.850	1.00
76_K	162_V	0.847	1.00
561_E	565_K	0.845	1.00
520_V	525_W	0.844	1.00
72_N	75_R	0.842	1.00
69_S	117_E	0.840	1.00
38_D	51_P	0.837	1.00
266_I	418_P	0.836	1.00
69_S	161_F	0.835	1.00
504_E	507_R	0.835	1.00
192_F	247_K	0.833	1.00
87_I	135_P	0.833	1.00
97_G	111_I	0.831	1.00
24_T	28_N	0.828	1.00
170_I	250_V	0.828	1.00
88_T	100_H	0.827	1.00
14_F	64_K	0.825	0.99
546_I	557_A	0.823	0.99
313_T	318_Y	0.823	0.99
405_R	408_E	0.821	0.99
18_K	61_W	0.821	0.99
412_S	415_S	0.819	0.99
200_D	203_G	0.818	0.99
192_F	196_F	0.818	0.99
173_Y	415_S	0.815	0.99
511_E	515_E	0.814	0.99
181_K	184_I	0.812	0.99
97_G	121_I	0.811	0.99
169_D	185_L	0.810	0.99
68_V	72_N	0.809	0.99
300_F	322_H	0.807	0.99
435_V	439_S	0.805	0.99
291_T	296_L	0.805	0.99
22_E	25_G	0.804	0.99
510_I	513_L	0.803	0.99
9_I	69_S	0.802	0.99
266_I	275_L	0.801	0.99
293_G	328_E	0.801	0.99
89_K	126_D	0.800	0.99
296_L	325_L	0.798	0.99
242_V	245_N	0.794	0.99
173_Y	181_K	0.793	0.99
165_C	240_M	0.790	0.99
198_L	220_V	0.789	0.99
337_P	373_M	0.789	0.99
411_K	436_D	0.789	0.99
177_Y	221_N	0.787	0.99
548_T	554_K	0.784	0.99
73_G	117_E	0.784	0.99
78_W	160_E	0.784	0.99
172_V	182_V	0.780	0.99
408_E	411_K	0.780	0.99
241_Y	244_G	0.779	0.99
383_V	386_Y	0.778	0.99
443_Y	478_I	0.778	0.99
105_T	373_M	0.777	0.99
268_L	384_I	0.777	0.99
267_Y	270_G	0.777	0.99
66_L	92_I	0.777	0.99
370_I	374_I	0.773	0.99
10_D	13_G	0.772	0.99
441_N	479_T	0.772	0.99
502_Q	506_I	0.771	0.99
68_V	161_F	0.771	0.99
252_E	379_N	0.771	0.99
546_I	556_A	0.771	0.99
182_V	196_F	0.770	0.99
440_L	443_Y	0.770	0.99
496_M	502_Q	0.769	0.99
264_G	272_P	0.768	0.99
498_S	501_Y	0.767	0.99
76_K	189_N	0.766	0.99
21_N	25_G	0.765	0.99
60_A	151_G	0.764	0.99
170_I	184_I	0.764	0.99
123_V	157_V	0.762	0.99
82_E	156_P	0.761	0.99
238_V	252_E	0.760	0.99
110_P	115_V	0.755	0.99
335_L	376_Q	0.752	0.99
474_K	480_E	0.752	0.99
253_R	327_D	0.751	0.99
184_I	194_L	0.751	0.99
501_Y	505_M	0.751	0.99
16_K	33_G	0.749	0.99
420_T	439_S	0.748	0.99
10_D	158_Y	0.747	0.99
339_L	366_V	0.745	0.99
506_I	509_Y	0.742	0.99
480_E	483_A	0.736	0.99
162_V	248_D	0.735	0.99
278_F	311_F	0.734	0.99
385_M	418_P	0.733	0.99
184_I	238_V	0.733	0.99
324_D	380_R	0.732	0.99
505_M	509_Y	0.732	0.99
80_V	106_Q	0.732	0.99
216_F	219_D	0.729	0.99
95_E	116_N	0.728	0.99
517_D	520_V	0.727	0.99
524_I	560_V	0.727	0.99
503_S	507_R	0.726	0.99
259_V	332_L	0.726	0.99
357_F	366_V	0.726	0.99
302_L	551_R	0.724	0.99
275_L	334_I	0.724	0.99
286_I	515_E	0.720	0.99
167_V	250_V	0.719	0.99
274_F	519_I	0.719	0.99
294_A	298_R	0.718	0.99
173_Y	378_K	0.718	0.99
273_I	309_N	0.715	0.99
278_F	527_F	0.713	0.99
310_S	505_M	0.711	0.98
64_K	121_I	0.711	0.98
320_N	324_D	0.709	0.98
446_W	449_E	0.707	0.98
296_L	322_H	0.707	0.98
102_G	338_P	0.706	0.98
94_G	120_K	0.704	0.98
278_F	546_I	0.703	0.98
135_P	138_R	0.702	0.98
320_N	377_H	0.702	0.98
313_T	322_H	0.698	0.98
155_R	319_S	0.696	0.98
506_I	510_I	0.695	0.98
303_M	547_F	0.694	0.98
443_Y	447_Y	0.694	0.98
82_E	106_Q	0.690	0.98
522_F	564_F	0.688	0.98
296_L	319_S	0.688	0.98
546_I	560_V	0.688	0.98
244_G	247_K	0.682	0.98
17_F	46_W	0.681	0.98
301_Y	304_R	0.680	0.98
204_R	207_L	0.680	0.98
364_E	367_R	0.680	0.98
502_Q	509_Y	0.679	0.98
171_T	174_T	0.678	0.98
259_V	418_P	0.678	0.98
308_A	564_F	0.678	0.98
388_V	407_V	0.677	0.98
209_E	218_K	0.676	0.98
481_F	510_I	0.675	0.98
16_K	37_E	0.674	0.98
281_H	316_Y	0.673	0.98
177_Y	225_P	0.673	0.98
171_T	416_S	0.673	0.98
19_I	60_A	0.672	0.98
489_L	493_P	0.672	0.98
506_I	560_V	0.672	0.98
297_V	321_E	0.672	0.98
88_T	109_F	0.670	0.98
237_I	241_Y	0.670	0.98
71_D	75_R	0.670	0.98
406_E	410_F	0.668	0.98
185_L	211_S	0.667	0.98
320_N	376_Q	0.666	0.98
64_K	68_V	0.663	0.98
482_G	489_L	0.662	0.98
326_A	331_F	0.662	0.98
282_E	289_K	0.661	0.98
466_E	469_K	0.660	0.98
19_I	58_G	0.658	0.98
509_Y	512_A	0.657	0.97
300_F	311_F	0.656	0.97
175_K	179_H	0.655	0.97
172_V	180_L	0.654	0.97
7_P	161_F	0.652	0.97
216_F	238_V	0.652	0.97
69_S	77_A	0.651	0.97
410_F	419_V	0.649	0.97
559_V	563_L	0.648	0.97
496_M	505_M	0.645	0.97
314_S	318_Y	0.642	0.97
511_E	514_R	0.642	0.97
445_G	449_E	0.641	0.97
413_L	416_S	0.638	0.97
468_H	472_P	0.638	0.97
192_F	242_V	0.637	0.97
111_I	114_K	0.636	0.97
389_M	403_I	0.635	0.97
529_D	554_K	0.635	0.97
50_N	54_D	0.633	0.97
277_G	310_S	0.633	0.97
362_Y	366_V	0.632	0.97
125_I	153_I	0.632	0.97
8_K	160_E	0.631	0.97
377_H	383_V	0.630	0.97
302_L	557_A	0.629	0.97
16_K	120_K	0.628	0.97
441_N	444_H	0.627	0.97
90_L	107_F	0.627	0.97
42_V	46_W	0.627	0.97
68_V	77_A	0.626	0.97
557_A	561_E	0.625	0.97
378_K	413_L	0.625	0.97
90_L	100_H	0.625	0.97
318_Y	322_H	0.625	0.97
296_L	321_E	0.624	0.97
18_K	36_S	0.623	0.97
365_K	369_T	0.623	0.97
156_P	321_E	0.622	0.97
484_D	489_L	0.621	0.96
11_L	42_V	0.621	0.96
40_I	46_W	0.621	0.96
231_P	268_L	0.620	0.96
52_K	55_Q	0.618	0.96
489_L	492_D	0.617	0.96
106_Q	377_H	0.617	0.96
487_Y	490_H	0.616	0.96
207_L	210_E	0.615	0.96
273_I	384_I	0.615	0.96
469_K	472_P	0.614	0.96
134_L	137_A	0.614	0.96
77_A	112_K	0.612	0.96
499_E	502_Q	0.612	0.96
498_S	502_Q	0.611	0.96
26_E	61_W	0.611	0.96
257_R	381_P	0.611	0.96
180_L	218_K	0.609	0.96
402_F	405_R	0.607	0.96
497_W	501_Y	0.606	0.96
505_M	508_K	0.605	0.96
90_L	98_G	0.605	0.96
113_L	117_E	0.605	0.96
194_L	240_M	0.603	0.96
278_F	303_M	0.601	0.96
93_N	116_N	0.600	0.96
266_I	385_M	0.599	0.96
196_F	209_E	0.598	0.96
478_I	481_F	0.598	0.96
259_V	268_L	0.597	0.96
184_I	196_F	0.597	0.96
106_Q	320_N	0.597	0.96
135_P	139_D	0.595	0.96
509_Y	513_L	0.595	0.96
68_V	111_I	0.595	0.96
252_E	324_D	0.594	0.96
313_T	335_L	0.594	0.96
191_R	242_V	0.594	0.96
182_V	236_L	0.593	0.95
203_G	207_L	0.592	0.95
229_D	268_L	0.592	0.95
500_E	503_S	0.592	0.95
47_N	85_G	0.591	0.95
84_A	100_H	0.591	0.95
420_T	479_T	0.590	0.95
404_R	434_Y	0.589	0.95
102_G	372_E	0.589	0.95
496_M	500_E	0.589	0.95
488_G	491_S	0.589	0.95
392_P	395_D	0.588	0.95
90_L	121_I	0.588	0.95
444_H	448_T	0.587	0.95
323_L	383_V	0.587	0.95
275_L	332_L	0.586	0.95
174_T	258_D	0.586	0.95
193_S	208_N	0.585	0.95
174_T	254_I	0.585	0.95
490_H	500_E	0.584	0.95
162_V	166_H	0.584	0.95
68_V	117_E	0.584	0.95
170_I	174_T	0.583	0.95
34_L	120_K	0.583	0.95
200_D	235_T	0.583	0.95
479_T	485_A	0.583	0.95
547_F	557_A	0.581	0.95
495_Q	502_Q	0.581	0.95
516_K	519_I	0.580	0.95
69_S	74_N	0.578	0.95
525_W	530_F	0.578	0.95
503_S	559_V	0.576	0.95
261_V	266_I	0.576	0.95
171_T	413_L	0.576	0.95
44_A	48_E	0.575	0.95
311_F	333_V	0.575	0.95
481_F	484_D	0.574	0.95
45_S	150_Y	0.574	0.95
388_V	419_V	0.573	0.95
512_A	515_E	0.572	0.94
520_V	523_H	0.571	0.94
393_P	396_I	0.570	0.94
284_F	287_L	0.569	0.94
172_V	175_K	0.569	0.94
487_Y	491_S	0.569	0.94
495_Q	501_Y	0.569	0.94
508_K	511_E	0.569	0.94
71_D	77_A	0.568	0.94
449_E	497_W	0.567	0.94
281_H	315_H	0.566	0.94
439_S	442_Y	0.566	0.94
506_I	556_A	0.562	0.94
305_K	553_P	0.561	0.94
128_T	151_G	0.560	0.94
51_P	54_D	0.559	0.94
507_R	559_V	0.559	0.94
475_P	480_E	0.557	0.94
410_F	415_S	0.557	0.94
295_V	298_R	0.556	0.94
441_N	447_Y	0.555	0.94
360_V	363_F	0.554	0.94
34_L	122_V	0.554	0.94
440_L	447_Y	0.553	0.93
438_I	441_N	0.553	0.93
42_V	48_E	0.553	0.93
52_K	133_N	0.552	0.93
547_F	553_P	0.552	0.93
42_V	62_Y	0.552	0.93
78_W	168_E	0.551	0.93
26_E	30_W	0.549	0.93
291_T	295_V	0.549	0.93
295_V	551_R	0.548	0.93
367_R	406_E	0.548	0.93
182_V	218_K	0.547	0.93
336_E	389_M	0.547	0.93
25_G	29_G	0.547	0.93
296_L	318_Y	0.545	0.93
87_I	126_D	0.544	0.93
388_V	406_E	0.544	0.93
202_E	232_Y	0.544	0.93
9_I	72_N	0.544	0.93
182_V	216_F	0.544	0.93
102_G	105_T	0.543	0.93
112_K	115_V	0.543	0.93
336_E	387_S	0.542	0.93
304_R	331_F	0.541	0.93
334_I	387_S	0.540	0.93
490_H	493_P	0.540	0.93
407_V	434_Y	0.538	0.93
468_H	471_F	0.538	0.93
432_L	438_I	0.537	0.92
201_K	235_T	0.537	0.92
75_R	164_E	0.537	0.92
491_S	494_P	0.537	0.92
306_I	553_P	0.536	0.92
308_A	560_V	0.536	0.92
27_E	30_W	0.535	0.92
205_V	209_E	0.535	0.92
30_W	34_L	0.534	0.92
225_P	258_D	0.534	0.92
45_S	290_F	0.534	0.92
179_H	182_V	0.533	0.92
209_E	216_F	0.533	0.92
370_I	409_L	0.533	0.92
363_F	367_R	0.533	0.92
187_E	211_S	0.532	0.92
513_L	522_F	0.532	0.92
201_K	328_E	0.532	0.92
86_Y	102_G	0.530	0.92
167_V	248_D	0.529	0.92
241_Y	245_N	0.529	0.92
186_S	240_M	0.528	0.92
318_Y	335_L	0.527	0.92
506_I	524_I	0.526	0.92
313_T	333_V	0.526	0.92
20_D	124_K	0.526	0.92
477_I	521_G	0.525	0.92
280_R	313_T	0.525	0.92
202_E	207_L	0.525	0.92
199_V	206_I	0.525	0.92
504_E	508_K	0.524	0.92
22_E	26_E	0.524	0.92
394_S	434_Y	0.524	0.92
177_Y	223_V	0.524	0.92
310_S	477_I	0.524	0.92
305_K	557_A	0.524	0.92
100_H	109_F	0.524	0.92
559_V	562_E	0.524	0.92
471_F	474_K	0.523	0.91
199_V	202_E	0.523	0.91
225_P	256_F	0.523	0.91
26_E	29_G	0.523	0.91
21_N	58_G	0.522	0.91
486_I	490_H	0.522	0.91
67_F	117_E	0.519	0.91
524_I	546_I	0.519	0.91
18_K	37_E	0.519	0.91
81_F	107_F	0.519	0.91
188_C	212_S	0.517	0.91
501_Y	509_Y	0.517	0.91
266_I	273_I	0.517	0.91
233_L	327_D	0.516	0.91
337_P	370_I	0.516	0.91
47_N	52_K	0.515	0.91
435_V	441_N	0.515	0.91
93_N	115_V	0.515	0.91
495_Q	503_S	0.514	0.91
370_I	373_M	0.513	0.91
501_Y	506_I	0.513	0.91
388_V	403_I	0.513	0.91
12_Q	64_K	0.512	0.91
496_M	499_E	0.511	0.91
501_Y	504_E	0.511	0.91
186_S	214_E	0.510	0.90
310_S	384_I	0.510	0.90
480_E	485_A	0.510	0.90
193_S	242_V	0.510	0.90
468_H	518_Y	0.509	0.90
527_F	530_F	0.508	0.90
13_G	64_K	0.508	0.90
108_K	168_E	0.508	0.90
443_Y	446_W	0.507	0.90
524_I	549_R	0.507	0.90
90_L	109_F	0.507	0.90
71_D	161_F	0.506	0.90
530_F	544_K	0.506	0.90
475_P	478_I	0.505	0.90
224_I	234_Y	0.505	0.90
282_E	322_H	0.504	0.90
153_I	157_V	0.504	0.90
320_N	380_R	0.503	0.90
83_G	103_S	0.503	0.90
499_E	503_S	0.503	0.90
11_L	121_I	0.503	0.90
317_P	373_M	0.502	0.90
496_M	509_Y	0.502	0.90
156_P	293_G	0.501	0.90
293_G	319_S	0.501	0.90
489_L	556_A	0.501	0.90
560_V	563_L	0.501	0.90
20_D	30_W	0.501	0.90
68_V	71_D	0.500	0.90
155_R	316_Y	0.500	0.90
441_N	445_G	0.500	0.90
121_I	157_V	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2je8A	1	0.914	100	0.23	Contact Map
4cvuA	2	0.9193	100	0.25	Contact Map
1jz7A	4	0.9228	100	0.252	Contact Map
3gm8A	1	0.9053	100	0.259	Contact Map
3bgaA	2	0.9053	100	0.26	Contact Map
3obaA	4	0.9211	100	0.262	Contact Map
4ypjA	1	0.9298	100	0.265	Contact Map
3cmgA	3	0.9386	100	0.268	Contact Map
3fn9A	4	0.9404	100	0.27	Contact Map
2vzsA	1	0.9158	100	0.271	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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