Q97UH5 - SULSO - GREMLIN Contacts

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Q97UH5 - ABC transporter, binding protein

UniProt:	Q97UH5	Sequences: MKRYKIISTIITVLMVISIGIFAMPILSQSTSVQPEGSMVIMPSPGIVWQDNFNPWNAPALPGGLIWLIYEPLALVNSLSGQIIPWLATNWTFTTGYVNLPNGTKVQTLALILYLRHDVYFTDGTPFNATAVWYTLALEQAYPQLGYSANQIANMTIINPYELEIVFKPGVTPMVLYTILEQWPVDPAQWGKIFPVEQLPNGTYVGLNKTGNPFTYPNTNPIGTGPYMLYSFSPQEIVLVANPHYWMPGEPRIKYLLYPSYPSNVQADTALNNGQITWAGLFEPNIQQQFVAKDPLHYHYYFAPGFPTMLTLNNLKWPLSDPVLRQAISLAINRTAIYYLGEYGYEPPATTPLPLPPQQLQYINSSVLQLAEQFAPPQGNVTAALQLLESHGYKLVNGQLITPNGTAVPAMTIITVAGWTDWDADLTLIAQDLKQIGITVEVQTPPFTTWYNYMETGNYWMGLMWDLISGPTPIQPLSGYLYGYWNSPGNITPIGNSTYYNIERFNLSIIHPTFEQLVNWANGNFSINDNAYYSIVNKLAALWIKYMPSIALVYGAEWYEYVNNTVTGWPTQQNYYWPAPPWTSLPSTPLPVVLALHLVNQSVPEPWWYYTSQVPSSWYTSNDPFVYQTTTTTTTSTTTTTSTTTTSTTTSTVTTTSVSTTTSVSTSVSTTTATVTTTVTSSSNTTLYAIIAVVVIIIVIIGVILGLRRR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	710 (536)
Sequences:	615 (523)
Seq/√Len:	22.6

ECOLI - YEJA NIKA SAPA YGIS
BACSU - APPA OPPA DPPE
HALSA - Q9HMW4
SULSO - Q97UH5 Q97UG7 Q97VF7 Q97VK5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
21_I	24_M	7.539	1.00
159_N	162_E	7.253	1.00
133_W	157_I	5.027	1.00
323_V	390_S	4.742	1.00
130_T	157_I	4.715	1.00
156_T	164_E	4.105	1.00
16_V	23_A	4.023	1.00
230_Y	240_V	3.817	1.00
94_T	109_L	3.688	1.00
385_L	389_E	3.428	1.00
328_I	433_L	3.406	1.00
118_D	126_P	3.398	1.00
155_M	163_L	3.316	1.00
487_S	511_H	3.286	1.00
158_I	164_E	3.215	1.00
126_P	161_Y	3.168	1.00
241_A	254_K	3.167	1.00
383_A	386_Q	3.076	1.00
505_F	546_Y	3.039	1.00
19_I	22_F	3.015	1.00
127_F	224_T	3.001	1.00
227_Y	253_I	2.959	0.99
54_N	138_L	2.950	0.99
330_L	383_A	2.846	0.99
410_A	439_T	2.671	0.99
114_Y	162_E	2.615	0.99
129_A	163_L	2.613	0.99
117_H	161_Y	2.538	0.98
509_I	512_P	2.518	0.98
396_V	399_Q	2.503	0.98
473_P	476_P	2.501	0.98
73_L	88_A	2.458	0.98
133_W	155_M	2.433	0.98
74_A	113_L	2.416	0.98
77_N	82_Q	2.409	0.98
512_P	516_Q	2.374	0.97
110_A	166_V	2.370	0.97
88_A	113_L	2.355	0.97
110_A	164_E	2.341	0.97
92_T	114_Y	2.307	0.97
201_N	205_V	2.278	0.97
157_I	160_P	2.262	0.97
93_F	111_L	2.258	0.97
112_I	162_E	2.255	0.97
323_V	387_L	2.241	0.96
94_T	110_A	2.230	0.96
410_A	441_E	2.227	0.96
17_I	23_A	2.204	0.96
446_P	449_T	2.204	0.96
20_G	24_M	2.185	0.96
385_L	395_L	2.173	0.96
157_I	163_L	2.171	0.96
119_V	224_T	2.105	0.95
227_Y	254_K	2.084	0.95
16_V	19_I	2.074	0.94
9_T	13_V	2.052	0.94
71_E	245_Y	2.051	0.94
15_M	18_S	2.034	0.94
228_M	240_V	1.998	0.93
130_T	133_W	1.996	0.93
382_T	386_Q	1.948	0.92
156_T	166_V	1.915	0.92
115_L	163_L	1.912	0.92
65_L	239_L	1.897	0.91
430_A	440_V	1.892	0.91
388_L	392_G	1.886	0.91
129_A	133_W	1.880	0.91
129_A	155_M	1.828	0.90
133_W	163_L	1.823	0.89
323_V	326_Q	1.795	0.89
12_T	18_S	1.782	0.88
9_T	19_I	1.772	0.88
103_G	109_L	1.750	0.87
386_Q	390_S	1.747	0.87
395_L	399_Q	1.734	0.87
533_Y	537_N	1.728	0.87
512_P	530_N	1.710	0.86
87_L	119_V	1.705	0.86
270_A	275_Q	1.703	0.86
389_E	400_L	1.696	0.86
130_T	160_P	1.693	0.86
65_L	69_I	1.679	0.85
531_A	534_S	1.676	0.85
132_V	198_Q	1.669	0.85
576_Y	579_A	1.649	0.84
329_S	547_M	1.647	0.84
429_I	433_L	1.626	0.83
13_V	19_I	1.625	0.83
17_I	22_F	1.614	0.83
155_M	312_L	1.601	0.82
43_P	46_G	1.592	0.82
238_V	255_Y	1.587	0.82
512_P	515_E	1.579	0.81
287_Q	290_F	1.575	0.81
95_T	438_I	1.574	0.81
24_M	27_L	1.568	0.81
326_Q	387_L	1.560	0.80
333_N	336_A	1.554	0.80
261_Y	266_Q	1.544	0.80
323_V	394_K	1.535	0.79
434_K	439_T	1.521	0.79
312_L	328_I	1.514	0.78
95_T	117_H	1.504	0.78
34_Q	37_G	1.500	0.78
122_T	242_N	1.500	0.78
228_M	243_P	1.499	0.78
207_L	210_T	1.496	0.78
129_A	158_I	1.494	0.77
53_F	232_F	1.475	0.77
135_T	198_Q	1.461	0.76
312_L	319_L	1.457	0.76
407_A	410_A	1.449	0.75
37_G	254_K	1.436	0.75
335_T	339_Y	1.434	0.74
119_V	246_W	1.417	0.74
516_Q	535_I	1.416	0.73
286_I	290_F	1.413	0.73
69_I	223_G	1.411	0.73
532_Y	536_V	1.411	0.73
12_T	28_S	1.410	0.73
13_V	16_V	1.410	0.73
133_W	137_A	1.405	0.73
242_N	245_Y	1.395	0.72
411_M	461_M	1.391	0.72
384_A	437_G	1.381	0.72
412_T	441_E	1.372	0.71
361_Q	387_L	1.367	0.71
124_G	226_P	1.363	0.71
114_Y	159_N	1.360	0.70
19_I	23_A	1.360	0.70
89_T	160_P	1.349	0.70
6_I	10_I	1.347	0.70
310_L	550_I	1.335	0.69
11_I	17_I	1.335	0.69
17_I	21_I	1.334	0.69
535_I	538_K	1.320	0.68
568_G	574_N	1.319	0.68
210_T	214_F	1.318	0.68
319_L	411_M	1.317	0.68
119_V	127_F	1.316	0.68
316_K	460_W	1.310	0.67
130_T	201_N	1.306	0.67
446_P	450_W	1.300	0.67
71_E	86_W	1.298	0.67
362_Y	367_V	1.286	0.66
327_A	388_L	1.284	0.66
387_L	390_S	1.280	0.66
574_N	578_P	1.279	0.66
569_W	572_Q	1.275	0.65
240_V	255_Y	1.275	0.65
392_G	405_G	1.273	0.65
310_L	429_I	1.272	0.65
123_D	277_T	1.269	0.65
121_F	223_G	1.266	0.65
380_N	383_A	1.264	0.65
13_V	18_S	1.264	0.65
94_T	103_G	1.257	0.64
400_L	403_P	1.255	0.64
334_R	378_Q	1.253	0.64
261_Y	282_F	1.250	0.64
158_I	162_E	1.246	0.63
501_N	504_R	1.243	0.63
247_M	250_E	1.242	0.63
499_Y	505_F	1.241	0.63
87_L	115_L	1.239	0.63
77_N	81_G	1.235	0.63
322_P	545_K	1.230	0.62
202_G	205_V	1.227	0.62
13_V	17_I	1.224	0.62
9_T	12_T	1.220	0.62
402_T	406_T	1.219	0.62
112_I	164_E	1.217	0.62
400_L	436_I	1.217	0.62
264_N	421_D	1.215	0.61
159_N	333_N	1.214	0.61
471_P	480_Y	1.211	0.61
211_G	442_V	1.208	0.61
413_I	426_L	1.208	0.61
113_L	165_I	1.208	0.61
467_L	472_T	1.207	0.61
33_V	36_E	1.203	0.61
493_P	498_T	1.202	0.61
5_K	10_I	1.198	0.60
199_L	202_G	1.196	0.60
8_S	12_T	1.190	0.60
12_T	158_I	1.190	0.60
569_W	577_W	1.186	0.60
14_L	44_S	1.184	0.59
324_L	393_Y	1.180	0.59
202_G	206_G	1.178	0.59
570_P	576_Y	1.178	0.59
118_D	389_E	1.173	0.59
18_S	22_F	1.172	0.59
388_L	405_G	1.168	0.58
119_V	161_Y	1.162	0.58
426_L	440_V	1.161	0.58
511_H	514_F	1.160	0.58
570_P	574_N	1.156	0.58
56_W	199_L	1.154	0.57
112_I	245_Y	1.152	0.57
321_D	473_P	1.148	0.57
128_N	131_A	1.144	0.57
88_A	91_W	1.144	0.57
115_L	535_I	1.143	0.57
238_V	257_L	1.142	0.57
74_A	245_Y	1.140	0.56
19_I	24_M	1.136	0.56
258_Y	306_F	1.136	0.56
528_N	532_Y	1.130	0.56
493_P	590_L	1.124	0.55
507_L	546_Y	1.124	0.55
341_G	513_T	1.122	0.55
472_T	532_Y	1.118	0.55
355_L	359_Q	1.117	0.55
526_S	531_A	1.115	0.55
542_L	546_Y	1.111	0.54
12_T	512_P	1.109	0.54
132_V	165_I	1.104	0.54
4_Y	17_I	1.101	0.54
449_T	453_Y	1.096	0.53
204_Y	209_K	1.091	0.53
322_P	546_Y	1.089	0.53
259_P	538_K	1.089	0.53
226_P	512_P	1.082	0.52
133_W	229_L	1.078	0.52
391_H	543_W	1.077	0.52
511_H	515_E	1.076	0.52
5_K	21_I	1.075	0.52
121_F	131_A	1.074	0.52
20_G	27_L	1.072	0.52
577_W	583_T	1.063	0.51
252_R	589_P	1.057	0.51
4_Y	10_I	1.056	0.51
495_G	500_Y	1.055	0.51
200_P	204_Y	1.047	0.50
433_L	438_I	1.036	0.49
332_I	429_I	1.034	0.49
226_P	327_A	1.033	0.49
155_M	165_I	1.031	0.49
538_K	550_I	1.031	0.49
210_T	213_P	1.028	0.49
14_L	18_S	1.027	0.49
18_S	28_S	1.027	0.49
16_V	21_I	1.023	0.48
115_L	243_P	1.017	0.48
5_K	15_M	1.016	0.48
348_P	351_T	1.015	0.48
253_I	512_P	1.012	0.48
568_G	579_A	1.012	0.48
505_F	508_S	1.012	0.48
327_A	387_L	1.011	0.48
438_I	450_W	1.010	0.48
170_G	528_N	1.007	0.47
312_L	485_W	1.007	0.47
310_L	441_E	1.003	0.47
11_I	18_S	1.000	0.47
21_I	25_P	0.996	0.47
37_G	41_I	0.987	0.46
331_A	436_I	0.984	0.46
10_I	509_I	0.981	0.46
118_D	251_P	0.980	0.45
123_D	437_G	0.979	0.45
95_T	130_T	0.979	0.45
23_A	333_N	0.976	0.45
37_G	244_H	0.973	0.45
111_L	127_F	0.968	0.45
438_I	453_Y	0.968	0.45
578_P	583_T	0.965	0.44
516_Q	531_A	0.963	0.44
335_T	443_Q	0.962	0.44
332_I	348_P	0.960	0.44
456_T	501_N	0.952	0.44
239_L	552_L	0.951	0.43
36_E	254_K	0.946	0.43
355_L	358_Q	0.945	0.43
123_D	418_G	0.940	0.43
13_V	545_K	0.937	0.43
71_E	224_T	0.935	0.42
122_T	125_T	0.935	0.42
430_A	434_K	0.932	0.42
579_A	584_S	0.926	0.42
277_T	405_G	0.924	0.42
506_N	511_H	0.924	0.42
55_P	223_G	0.920	0.41
89_T	162_E	0.919	0.41
222_I	227_Y	0.914	0.41
407_A	439_T	0.914	0.41
270_A	276_I	0.912	0.41
227_Y	562_V	0.910	0.41
120_Y	126_P	0.909	0.41
153_A	324_L	0.908	0.41
85_P	243_P	0.907	0.41
19_I	27_L	0.906	0.40
197_E	200_P	0.902	0.40
528_N	531_A	0.901	0.40
510_I	539_L	0.899	0.40
568_G	577_W	0.898	0.40
176_L	181_E	0.893	0.40
430_A	442_V	0.892	0.40
85_P	129_A	0.891	0.39
315_L	504_R	0.890	0.39
51_D	243_P	0.889	0.39
274_G	560_E	0.888	0.39
227_Y	232_F	0.887	0.39
17_I	382_T	0.886	0.39
385_L	400_L	0.885	0.39
281_L	284_P	0.885	0.39
252_R	332_I	0.884	0.39
14_L	333_N	0.883	0.39
125_T	201_N	0.883	0.39
10_I	18_S	0.882	0.39
338_Y	348_P	0.882	0.39
240_V	328_I	0.878	0.39
20_G	25_P	0.878	0.39
50_Q	568_G	0.875	0.38
15_M	22_F	0.873	0.38
226_P	275_Q	0.873	0.38
568_G	573_Q	0.872	0.38
115_L	160_P	0.865	0.38
256_L	589_P	0.858	0.37
569_W	573_Q	0.858	0.37
116_R	245_Y	0.857	0.37
570_P	573_Q	0.853	0.37
232_F	265_V	0.852	0.37
4_Y	9_T	0.851	0.37
419_W	422_W	0.850	0.37
41_I	46_G	0.848	0.37
401_I	404_N	0.847	0.37
90_N	114_Y	0.843	0.36
201_N	442_V	0.843	0.36
5_K	8_S	0.841	0.36
42_M	557_E	0.841	0.36
392_G	437_G	0.839	0.36
444_T	449_T	0.837	0.36
128_N	437_G	0.835	0.36
431_Q	434_K	0.829	0.35
40_V	46_G	0.829	0.35
41_I	240_V	0.829	0.35
6_I	205_V	0.829	0.35
39_M	46_G	0.828	0.35
132_V	135_T	0.827	0.35
271_L	467_L	0.826	0.35
379_G	429_I	0.825	0.35
309_M	466_D	0.825	0.35
153_A	168_K	0.825	0.35
263_S	432_D	0.823	0.35
23_A	32_S	0.823	0.35
328_I	542_L	0.821	0.35
253_I	508_S	0.821	0.35
202_G	227_Y	0.818	0.35
275_Q	484_Y	0.818	0.35
574_N	580_P	0.816	0.35
509_I	513_T	0.814	0.35
96_G	109_L	0.810	0.34
243_P	254_K	0.809	0.34
249_G	405_G	0.809	0.34
296_L	519_N	0.808	0.34
91_W	94_T	0.807	0.34
130_T	134_Y	0.806	0.34
36_E	40_V	0.805	0.34
407_A	517_L	0.805	0.34
87_L	550_I	0.805	0.34
77_N	84_I	0.804	0.34
180_L	196_V	0.803	0.34
218_N	221_P	0.802	0.34
42_M	267_A	0.801	0.34
222_I	225_G	0.797	0.33
39_M	44_S	0.797	0.33
495_G	498_T	0.796	0.33
568_G	571_T	0.794	0.33
337_I	425_D	0.794	0.33
159_N	399_Q	0.793	0.33
20_G	60_A	0.792	0.33
285_N	290_F	0.790	0.33
66_I	407_A	0.787	0.33
327_A	384_A	0.787	0.33
137_A	360_L	0.786	0.33
136_L	165_I	0.785	0.33
500_Y	503_E	0.784	0.33
4_Y	254_K	0.783	0.33
89_T	346_E	0.781	0.33
120_Y	534_S	0.780	0.32
226_P	437_G	0.777	0.32
550_I	584_S	0.777	0.32
500_Y	504_R	0.775	0.32
435_Q	588_T	0.774	0.32
395_L	398_G	0.773	0.32
474_I	479_G	0.772	0.32
569_W	574_N	0.771	0.32
21_I	78_S	0.771	0.32
239_L	305_G	0.768	0.32
363_I	413_I	0.767	0.32
398_G	401_I	0.767	0.32
6_I	24_M	0.767	0.32
426_L	555_G	0.764	0.31
90_N	231_S	0.763	0.31
261_Y	267_A	0.762	0.31
23_A	530_N	0.762	0.31
122_T	265_V	0.760	0.31
328_I	461_M	0.760	0.31
25_P	386_Q	0.760	0.31
570_P	580_P	0.760	0.31
114_Y	230_Y	0.758	0.31
517_L	535_I	0.757	0.31
449_T	461_M	0.756	0.31
208_N	212_N	0.755	0.31
342_E	346_E	0.752	0.31
94_T	112_I	0.751	0.31
321_D	390_S	0.748	0.31
438_I	441_E	0.747	0.30
14_L	89_T	0.746	0.30
514_F	539_L	0.745	0.30
447_F	464_M	0.745	0.30
12_T	17_I	0.745	0.30
173_P	390_S	0.745	0.30
124_G	437_G	0.740	0.30
12_T	509_I	0.740	0.30
216_Y	459_Y	0.740	0.30
28_S	117_H	0.738	0.30
82_Q	382_T	0.737	0.30
54_N	225_G	0.737	0.30
232_F	268_D	0.737	0.30
138_L	142_Y	0.735	0.30
12_T	22_F	0.735	0.30
90_N	317_W	0.734	0.30
16_V	45_P	0.732	0.30
16_V	379_G	0.732	0.30
382_T	390_S	0.732	0.30
222_I	548_P	0.731	0.30
445_P	449_T	0.731	0.30
312_L	332_I	0.731	0.30
200_P	203_T	0.729	0.29
309_M	354_P	0.727	0.29
16_V	20_G	0.726	0.29
303_A	556_A	0.726	0.29
337_I	429_I	0.726	0.29
228_M	239_L	0.725	0.29
126_P	310_L	0.725	0.29
123_D	528_N	0.724	0.29
111_L	242_N	0.724	0.29
418_G	442_V	0.722	0.29
385_L	436_I	0.722	0.29
116_R	170_G	0.722	0.29
212_N	470_G	0.722	0.29
441_E	455_E	0.722	0.29
251_P	568_G	0.721	0.29
59_P	146_G	0.720	0.29
397_N	407_A	0.720	0.29
20_G	502_I	0.718	0.29
426_L	442_V	0.715	0.29
405_G	408_V	0.714	0.29
226_P	328_I	0.714	0.29
339_Y	386_Q	0.711	0.28
204_Y	221_P	0.710	0.28
450_W	484_Y	0.709	0.28
9_T	25_P	0.707	0.28
69_I	119_V	0.706	0.28
265_V	268_D	0.706	0.28
251_P	392_G	0.705	0.28
540_A	544_I	0.705	0.28
247_M	251_P	0.705	0.28
415_T	423_D	0.704	0.28
334_R	554_Y	0.703	0.28
394_K	398_G	0.702	0.28
45_P	553_V	0.699	0.28
253_I	309_M	0.698	0.28
379_G	514_F	0.697	0.28
177_Y	181_E	0.696	0.28
390_S	410_A	0.695	0.28
460_W	499_Y	0.695	0.28
7_I	10_I	0.694	0.27
34_Q	38_S	0.694	0.27
130_T	163_L	0.693	0.27
119_V	126_P	0.692	0.27
298_Y	434_K	0.690	0.27
286_I	289_Q	0.690	0.27
112_I	121_F	0.687	0.27
7_I	21_I	0.686	0.27
54_N	266_Q	0.686	0.27
75_L	324_L	0.685	0.27
538_K	541_A	0.684	0.27
435_Q	456_T	0.684	0.27
131_A	437_G	0.681	0.27
348_P	355_L	0.680	0.27
200_P	277_T	0.680	0.27
33_V	39_M	0.679	0.27
130_T	570_P	0.679	0.27
543_W	551_A	0.679	0.27
95_T	156_T	0.678	0.27
234_P	330_L	0.676	0.26
103_G	110_A	0.674	0.26
17_I	20_G	0.674	0.26
293_K	550_I	0.674	0.26
331_A	381_V	0.672	0.26
6_I	14_L	0.671	0.26
73_L	87_L	0.671	0.26
514_F	579_A	0.670	0.26
213_P	216_Y	0.670	0.26
577_W	580_P	0.670	0.26
493_P	504_R	0.669	0.26
12_T	66_I	0.668	0.26
114_Y	470_G	0.668	0.26
16_V	34_Q	0.668	0.26
447_F	453_Y	0.666	0.26
154_N	166_V	0.665	0.26
179_I	296_L	0.665	0.26
362_Y	366_S	0.665	0.26
570_P	577_W	0.664	0.26
85_P	88_A	0.663	0.26
109_L	170_G	0.663	0.26
574_N	579_A	0.663	0.26
504_R	507_L	0.663	0.26
575_Y	578_P	0.661	0.26
11_I	550_I	0.661	0.26
327_A	437_G	0.659	0.26
356_P	360_L	0.657	0.25
306_F	362_Y	0.657	0.25
20_G	23_A	0.654	0.25
416_V	421_D	0.654	0.25
245_Y	566_V	0.653	0.25
457_G	504_R	0.653	0.25
160_P	386_Q	0.653	0.25
274_G	562_V	0.653	0.25
78_S	472_T	0.651	0.25
9_T	16_V	0.649	0.25
571_T	577_W	0.649	0.25
121_F	128_N	0.649	0.25
169_P	546_Y	0.648	0.25
149_A	168_K	0.647	0.25
115_L	226_P	0.646	0.25
335_T	348_P	0.646	0.25
124_G	128_N	0.644	0.25
88_A	253_I	0.644	0.25
74_A	176_L	0.643	0.25
587_S	591_P	0.643	0.25
329_S	377_P	0.643	0.25
17_I	24_M	0.642	0.25
508_S	589_P	0.641	0.25
88_A	317_W	0.641	0.25
6_I	9_T	0.641	0.25
239_L	516_Q	0.639	0.25
126_P	160_P	0.638	0.25
86_W	539_L	0.638	0.25
38_S	227_Y	0.638	0.25
413_I	423_D	0.638	0.25
32_S	435_Q	0.637	0.24
74_A	95_T	0.637	0.24
103_G	111_L	0.637	0.24
117_H	130_T	0.637	0.24
198_Q	271_L	0.636	0.24
448_T	453_Y	0.636	0.24
118_D	252_R	0.636	0.24
314_N	548_P	0.635	0.24
27_L	32_S	0.635	0.24
54_N	222_I	0.633	0.24
40_V	43_P	0.633	0.24
13_V	159_N	0.633	0.24
6_I	27_L	0.632	0.24
387_L	405_G	0.632	0.24
202_G	207_L	0.631	0.24
11_I	306_F	0.631	0.24
485_W	566_V	0.630	0.24
17_I	496_N	0.629	0.24
312_L	450_W	0.629	0.24
326_Q	374_F	0.629	0.24
132_V	392_G	0.629	0.24
116_R	397_N	0.628	0.24
95_T	110_A	0.627	0.24
137_A	141_A	0.627	0.24
173_P	243_P	0.627	0.24
61_L	464_M	0.626	0.24
242_N	532_Y	0.626	0.24
280_G	284_P	0.625	0.24
68_L	475_Q	0.625	0.24
135_T	163_L	0.625	0.24
575_Y	579_A	0.625	0.24
242_N	253_I	0.625	0.24
78_S	589_P	0.625	0.24
15_M	538_K	0.621	0.24
50_Q	540_A	0.621	0.24
438_I	561_Y	0.619	0.24
54_N	119_V	0.619	0.24
13_V	293_K	0.618	0.24
60_A	422_W	0.617	0.23
472_T	475_Q	0.614	0.23
253_I	566_V	0.614	0.23
54_N	433_L	0.613	0.23
57_N	420_T	0.613	0.23
239_L	430_A	0.613	0.23
173_P	240_V	0.612	0.23
26_I	130_T	0.612	0.23
567_T	570_P	0.612	0.23
277_T	565_T	0.612	0.23
124_G	131_A	0.612	0.23
152_I	165_I	0.611	0.23
89_T	116_R	0.611	0.23
68_L	471_P	0.611	0.23
11_I	36_E	0.610	0.23
517_L	532_Y	0.609	0.23
163_L	344_G	0.609	0.23
241_A	250_E	0.609	0.23
173_P	396_V	0.609	0.23
12_T	87_L	0.609	0.23
568_G	572_Q	0.608	0.23
127_F	276_I	0.608	0.23
118_D	161_Y	0.606	0.23
121_F	482_Y	0.606	0.23
85_P	437_G	0.605	0.23
137_A	154_N	0.604	0.23
176_L	179_I	0.604	0.23
60_A	136_L	0.603	0.23
115_L	293_K	0.603	0.23
389_E	574_N	0.602	0.23
116_R	377_P	0.602	0.23
53_F	227_Y	0.602	0.23
119_V	142_Y	0.601	0.23
57_N	60_A	0.601	0.23
90_N	110_A	0.601	0.23
321_D	324_L	0.600	0.23
12_T	19_I	0.600	0.23
328_I	583_T	0.599	0.23
5_K	160_P	0.599	0.23
43_P	434_K	0.598	0.23
89_T	572_Q	0.598	0.23
209_K	306_F	0.597	0.22
357_P	390_S	0.597	0.22
11_I	22_F	0.596	0.22
77_N	175_V	0.595	0.22
14_L	285_N	0.595	0.22
156_T	406_T	0.595	0.22
4_Y	12_T	0.593	0.22
11_I	161_Y	0.592	0.22
69_I	464_M	0.592	0.22
213_P	221_P	0.592	0.22
77_N	111_L	0.591	0.22
566_V	590_L	0.589	0.22
291_V	528_N	0.589	0.22
233_S	448_T	0.588	0.22
69_I	221_P	0.588	0.22
184_P	202_G	0.588	0.22
225_G	551_A	0.588	0.22
72_P	434_K	0.586	0.22
123_D	404_N	0.586	0.22
566_V	583_T	0.585	0.22
497_S	501_N	0.585	0.22
115_L	381_V	0.584	0.22
385_L	512_P	0.583	0.22
413_I	463_L	0.583	0.22
39_M	121_F	0.583	0.22
113_L	176_L	0.582	0.22
119_V	474_I	0.582	0.22
69_I	224_T	0.581	0.22
463_L	552_L	0.580	0.22
184_P	200_P	0.580	0.22
121_F	385_L	0.579	0.22
150_N	153_A	0.579	0.22
229_L	510_I	0.579	0.22
253_I	326_Q	0.579	0.22
18_S	230_Y	0.578	0.22
22_F	538_K	0.578	0.22
114_Y	164_E	0.578	0.22
138_L	271_L	0.578	0.22
382_T	399_Q	0.578	0.22
203_T	207_L	0.577	0.22
86_W	120_Y	0.577	0.22
267_A	282_F	0.576	0.21
60_A	281_L	0.574	0.21
235_Q	428_L	0.574	0.21
310_L	558_W	0.574	0.21
21_I	556_A	0.574	0.21
229_L	306_F	0.574	0.21
336_A	349_A	0.572	0.21
459_Y	504_R	0.572	0.21
316_K	394_K	0.572	0.21
36_E	84_I	0.571	0.21
214_F	221_P	0.571	0.21
317_W	320_S	0.570	0.21
33_V	550_I	0.569	0.21
141_A	333_N	0.569	0.21
110_A	156_T	0.569	0.21
333_N	355_L	0.568	0.21
7_I	83_I	0.568	0.21
110_A	408_V	0.568	0.21
11_I	27_L	0.564	0.21
128_N	256_L	0.562	0.21
278_W	581_P	0.561	0.21
234_P	257_L	0.560	0.21
55_P	138_L	0.560	0.21
89_T	382_T	0.560	0.21
110_A	149_A	0.560	0.21
392_G	398_G	0.558	0.21
229_L	280_G	0.558	0.21
69_I	127_F	0.557	0.21
230_Y	575_Y	0.557	0.21
452_N	455_E	0.557	0.21
501_N	505_F	0.556	0.21
517_L	536_V	0.556	0.21
11_I	410_A	0.555	0.21
586_P	589_P	0.555	0.21
326_Q	547_M	0.555	0.21
73_L	115_L	0.554	0.20
214_F	232_F	0.553	0.20
324_L	408_V	0.552	0.20
35_P	566_V	0.552	0.20
12_T	362_Y	0.552	0.20
241_A	542_L	0.551	0.20
88_A	157_I	0.549	0.20
207_L	407_A	0.549	0.20
21_I	26_I	0.548	0.20
448_T	452_N	0.548	0.20
393_Y	405_G	0.548	0.20
15_M	65_L	0.548	0.20
149_A	200_P	0.545	0.20
443_Q	453_Y	0.545	0.20
496_N	509_I	0.544	0.20
316_K	323_V	0.544	0.20
109_L	169_P	0.544	0.20
268_D	272_N	0.543	0.20
168_K	438_I	0.543	0.20
85_P	91_W	0.543	0.20
516_Q	519_N	0.543	0.20
395_L	400_L	0.543	0.20
501_N	507_L	0.543	0.20
362_Y	386_Q	0.542	0.20
179_I	485_W	0.542	0.20
181_E	235_Q	0.542	0.20
87_L	293_K	0.542	0.20
56_W	138_L	0.542	0.20
318_P	405_G	0.541	0.20
51_D	449_T	0.539	0.20
109_L	179_I	0.539	0.20
41_I	276_I	0.538	0.20
115_L	128_N	0.538	0.20
239_L	281_L	0.538	0.20
87_L	459_Y	0.537	0.20
273_N	435_Q	0.536	0.20
234_P	256_L	0.535	0.20
69_I	519_N	0.535	0.20
166_V	385_L	0.535	0.20
281_L	287_Q	0.535	0.20
411_M	414_I	0.533	0.20
96_G	557_E	0.532	0.20
294_D	299_H	0.532	0.20
138_L	467_L	0.532	0.20
426_L	496_N	0.530	0.19
579_A	583_T	0.530	0.19
364_N	398_G	0.529	0.19
32_S	390_S	0.529	0.19
159_N	581_P	0.528	0.19
117_H	126_P	0.528	0.19
222_I	545_K	0.528	0.19
198_Q	204_Y	0.527	0.19
87_L	163_L	0.526	0.19
577_W	582_W	0.526	0.19
322_P	474_I	0.525	0.19
496_N	500_Y	0.525	0.19
37_G	43_P	0.525	0.19
11_I	25_P	0.524	0.19
20_G	550_I	0.524	0.19
12_T	24_M	0.523	0.19
92_T	159_N	0.523	0.19
87_L	132_V	0.523	0.19
581_P	584_S	0.523	0.19
136_L	418_G	0.522	0.19
180_L	236_E	0.522	0.19
541_A	545_K	0.521	0.19
88_A	153_A	0.519	0.19
538_K	576_Y	0.519	0.19
578_P	582_W	0.519	0.19
72_P	80_S	0.519	0.19
116_R	119_V	0.518	0.19
226_P	438_I	0.518	0.19
391_H	532_Y	0.518	0.19
118_D	516_Q	0.517	0.19
443_Q	508_S	0.515	0.19
436_I	532_Y	0.514	0.19
309_M	346_E	0.513	0.19
393_Y	543_W	0.513	0.19
55_P	392_G	0.512	0.19
175_V	473_P	0.512	0.19
133_W	156_T	0.510	0.19
243_P	253_I	0.509	0.19
8_S	24_M	0.509	0.19
209_K	442_V	0.508	0.18
38_S	50_Q	0.508	0.18
12_T	542_L	0.506	0.18
498_T	505_F	0.506	0.18
141_A	296_L	0.506	0.18
16_V	236_E	0.505	0.18
308_T	419_W	0.505	0.18
73_L	132_V	0.504	0.18
476_P	532_Y	0.504	0.18
225_G	467_L	0.503	0.18
327_A	514_F	0.503	0.18
57_N	446_P	0.503	0.18
178_T	481_L	0.503	0.18
242_N	274_G	0.502	0.18
8_S	17_I	0.501	0.18
129_A	159_N	0.501	0.18
132_V	163_L	0.501	0.18
168_K	373_Q	0.501	0.18
579_A	587_S	0.501	0.18
115_L	398_G	0.501	0.18
321_D	391_H	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qflA	1	0.6789	100	0.486	Contact Map
4wedA	1	0.6648	100	0.488	Contact Map
4pfyA	1	0.731	100	0.493	Contact Map
4pfuA	2	0.7324	100	0.493	Contact Map
2o7iA	1	0.7817	100	0.493	Contact Map
1xocA	2	0.6958	100	0.493	Contact Map
1zu0A	1	0.7268	100	0.493	Contact Map
4fajA	1	0.6732	100	0.498	Contact Map
4oevA	1	0.6901	100	0.501	Contact Map
3zs6A	1	0.6817	100	0.504	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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