GREMLIN Database
Q97UF4 - Arabinose ABC transporter, permease
UniProt: Q97UF4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 285 (250)
Sequences: 69157 (45189)
Seq/√Len: 2858.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
193_Y197_R3.9831.00
63_T67_V3.1951.00
185_K194_L3.0171.00
170_L174_M2.9971.00
30_S49_Y2.6131.00
60_L63_T2.5741.00
184_A194_L2.5111.00
71_A154_I2.5081.00
190_N193_Y2.5071.00
181_I199_I2.4971.00
172_S206_G2.4781.00
75_I158_T2.4721.00
50_Q54_S2.3951.00
47_G50_Q2.3201.00
59_S63_T2.3081.00
73_V211_T2.2871.00
191_N194_L2.2851.00
169_F207_L2.2191.00
192_F196_F2.1881.00
251_Y254_L2.1481.00
47_G51_T2.1341.00
189_A193_Y2.0231.00
93_N96_R2.0211.00
81_I195_L2.0041.00
193_Y196_F1.9821.00
165_A210_S1.9641.00
88_Y174_M1.9291.00
67_V150_Y1.9261.00
173_F203_S1.9111.00
180_I202_N1.9011.00
28_Y32_L1.8741.00
100_L170_L1.8421.00
184_A189_A1.8241.00
90_L181_I1.7871.00
77_N211_T1.7831.00
81_I203_S1.7591.00
24_A28_Y1.7191.00
60_L64_H1.7121.00
240_V244_Y1.7091.00
181_I194_L1.7071.00
185_K191_N1.6911.00
69_T215_F1.6781.00
81_I169_F1.6451.00
72_A218_S1.6351.00
51_T254_L1.6271.00
80_G165_A1.6151.00
271_I275_I1.6091.00
67_V71_A1.6061.00
181_I185_K1.5911.00
87_L166_V1.5831.00
83_G166_V1.5701.00
237_M243_I1.5461.00
27_V260_S1.5331.00
240_V243_I1.5171.00
238_S241_E1.4901.00
237_M240_V1.4701.00
10_I14_I1.4561.00
90_L178_K1.4561.00
165_A214_L1.4451.00
178_K181_I1.4411.00
95_R98_I1.4371.00
21_Y25_L1.4371.00
92_S96_R1.4271.00
222_F226_F1.4191.00
51_T54_S1.4051.00
84_A169_F1.3971.00
46_L50_Q1.3861.00
209_V213_L1.3811.00
88_Y170_L1.3731.00
57_F60_L1.3611.00
78_I82_L1.3601.00
25_L29_F1.3491.00
200_L207_L1.3481.00
45_G48_T1.3421.00
76_G214_L1.3401.00
173_F199_I1.3351.00
169_F210_S1.3191.00
242_Y246_L1.3141.00
241_E245_I1.3101.00
238_S242_Y1.2751.00
81_I207_L1.2671.00
275_I278_L1.2451.00
156_I228_I1.2431.00
61_A240_V1.2421.00
178_K182_E1.2421.00
179_S182_E1.2361.00
184_A198_I1.2331.00
122_F152_G1.2301.00
85_G173_F1.2221.00
224_V228_I1.2041.00
176_V202_N1.1941.00
74_A78_I1.1851.00
98_I101_S1.1811.00
239_L242_Y1.1711.00
64_H67_V1.1521.00
237_M246_L1.1471.00
71_A74_A1.1401.00
240_V246_L1.1331.00
231_P234_P1.1311.00
275_I279_K1.1281.00
245_I249_T1.1241.00
204_M208_I1.1121.00
33_N36_L1.1111.00
36_L43_F1.1101.00
77_N207_L1.1061.00
162_T166_V1.1001.00
141_I144_T1.0951.00
190_N194_L1.0941.00
154_I158_T1.0901.00
98_I102_V1.0801.00
26_N260_S1.0731.00
153_M225_P1.0701.00
88_Y173_F1.0661.00
169_F206_G1.0641.00
142_W151_A1.0521.00
272_P276_L1.0481.00
65_T238_S1.0401.00
120_W124_P1.0381.00
9_S13_F1.0361.00
71_A75_I1.0331.00
237_M242_Y1.0311.00
238_S244_Y1.0301.00
75_I154_I1.0271.00
85_G195_L1.0241.00
96_R174_M1.0201.00
150_Y154_I1.0101.00
229_G234_P1.0091.00
168_F210_S1.0081.00
72_A157_E1.0061.00
202_N205_N1.0041.00
189_A194_L1.0031.00
151_A155_I1.0031.00
238_S243_I1.0021.00
53_F59_S0.9961.00
25_L28_Y0.9871.00
194_L197_R0.9841.00
221_I224_V0.9831.00
181_I191_N0.9811.00
85_G191_N0.9801.00
82_L86_I0.9781.00
221_I225_P0.9661.00
64_H150_Y0.9601.00
243_I246_L0.9551.00
72_A76_G0.9531.00
66_I70_I0.9481.00
118_W228_I0.9461.00
84_A88_Y0.9431.00
10_I13_F0.9411.00
72_A154_I0.9301.00
48_T253_S0.9171.00
150_Y234_P0.9161.00
237_M241_E0.9101.00
74_A211_T0.9091.00
49_Y260_S0.9061.00
104_L167_L0.9021.00
118_W156_I0.9001.00
70_I74_A0.8971.00
156_I224_V0.8961.00
67_V151_A0.8871.00
157_E218_S0.8851.00
35_S38_N0.8841.00
76_G80_G0.8811.00
67_V70_I0.8771.00
40_Q43_F0.8761.00
51_T55_E0.8741.00
34_W38_N0.8731.00
266_A270_I0.8651.00
203_S206_G0.8631.00
58_F258_L0.8631.00
68_Y150_Y0.8601.00
29_F256_S0.8591.00
62_V66_I0.8581.00
111_S160_A0.8521.00
115_A223_T0.8471.00
31_L44_A0.8471.00
239_L243_I0.8451.00
172_S203_S0.8441.00
165_A169_F0.8431.00
55_E59_S0.8371.00
84_A166_V0.8321.00
204_M207_L0.8301.00
9_S12_G0.8281.00
80_G166_V0.8281.00
94_T97_A0.8251.00
16_A20_I0.8251.00
97_A100_L0.8231.00
52_L261_L0.8221.00
87_L100_L0.8221.00
119_Q123_N0.8161.00
169_F203_S0.8131.00
237_M244_Y0.8131.00
86_I93_N0.8121.00
151_A154_I0.8111.00
68_Y157_E0.8071.00
32_L36_L0.8041.00
195_L200_L0.8041.00
194_L199_I0.7981.00
196_F200_L0.7971.00
11_P14_I0.7961.00
191_N195_L0.7901.00
75_I78_I0.7881.00
63_T66_I0.7861.00
29_F32_L0.7841.00
246_L255_S0.7831.00
204_M276_L0.7801.00
268_V272_P0.7781.00
273_Y276_L0.7781.00
71_A158_T0.7781.00
61_A242_Y0.7701.00
214_L218_S0.7671.00
84_A173_F0.7671.00
33_N43_F0.7631.00
7_L10_I0.7621.00
272_P275_I0.7621.00
189_A197_R0.7591.00
30_S34_W0.7581.00
76_G161_Y0.7521.00
61_A64_H0.7521.00
44_A47_G0.7471.00
77_N169_F0.7411.00
244_Y248_S0.7381.00
26_N259_S0.7321.00
180_I198_I0.7291.00
21_Y24_A0.7281.00
114_Y159_W0.7281.00
56_Y60_L0.7271.00
83_G162_T0.7251.00
169_F173_F0.7241.00
247_F250_E0.7151.00
14_I17_A0.7121.00
111_S223_T0.7101.00
73_V215_F0.7101.00
241_E258_L0.7091.00
32_L41_P0.7061.00
29_F33_N0.7041.00
115_A227_T0.7011.00
76_G218_S0.6981.00
51_T251_Y0.6981.00
161_Y214_L0.6961.00
104_L107_L0.6961.00
80_G169_F0.6931.00
26_N256_S0.6921.00
87_L170_L0.6911.00
176_V203_S0.6911.00
254_L258_L0.6891.00
15_F19_L0.6871.00
195_L199_I0.6861.00
149_I152_G0.6821.00
31_L45_G0.6821.00
87_L99_Y0.6791.00
69_T73_V0.6791.00
207_L210_S0.6781.00
79_L162_T0.6781.00
241_E244_Y0.6781.00
50_Q53_F0.6771.00
256_S260_S0.6721.00
76_G165_A0.6721.00
120_W123_N0.6711.00
161_Y217_F0.6701.00
245_I251_Y0.6691.00
91_K94_T0.6671.00
183_A187_D0.6661.00
45_G49_Y0.6621.00
178_K185_K0.6601.00
267_A271_I0.6571.00
16_A19_L0.6561.00
48_T51_T0.6551.00
52_L258_L0.6531.00
46_L49_Y0.6521.00
242_Y245_I0.6511.00
100_L167_L0.6501.00
199_I202_N0.6501.00
86_I91_K0.6471.00
183_A186_I0.6471.00
56_Y59_S0.6471.00
237_M245_I0.6451.00
59_S62_V0.6401.00
206_G210_S0.6401.00
7_L11_P0.6381.00
112_S227_T0.6381.00
73_V77_N0.6381.00
68_Y153_M0.6361.00
152_G156_I0.6341.00
29_F34_W0.6341.00
144_T231_P0.6301.00
83_G103_F0.6291.00
262_V266_A0.6291.00
33_N42_S0.6291.00
79_L158_T0.6251.00
36_L42_S0.6241.00
248_S251_Y0.6221.00
93_N99_Y0.6211.00
68_Y154_I0.6191.00
92_S97_A0.6151.00
103_F163_G0.6141.00
76_G158_T0.6141.00
207_L211_T0.6101.00
27_V31_L0.6081.00
52_L254_L0.6061.00
152_G228_I0.6041.00
91_K96_R0.6031.00
223_T227_T0.6021.00
65_T219_F0.5991.00
41_P44_A0.5951.00
43_F47_G0.5951.00
271_I274_A0.5941.00
30_S257_A0.5941.00
229_G232_T0.5901.00
32_L43_F0.5871.00
85_G199_I0.5871.00
229_G233_N0.5861.00
118_W121_L0.5841.00
49_Y257_A0.5831.00
153_M157_E0.5821.00
276_L279_K0.5791.00
8_M11_P0.5791.00
95_R99_Y0.5761.00
69_T218_S0.5751.00
68_Y72_A0.5741.00
107_L163_G0.5731.00
168_F206_G0.5731.00
22_L27_V0.5701.00
223_T226_F0.5701.00
157_E221_I0.5631.00
20_I24_A0.5631.00
106_P163_G0.5631.00
216_L220_R0.5611.00
30_S260_S0.5601.00
97_A101_S0.5591.00
153_M229_G0.5581.00
157_E160_A0.5571.00
211_T214_L0.5561.00
208_I211_T0.5541.00
124_P141_I0.5531.00
84_A170_L0.5531.00
270_I274_A0.5511.00
101_S105_Y0.5501.00
119_Q143_L0.5491.00
252_F256_S0.5481.00
107_L164_L0.5471.00
69_T219_F0.5461.00
115_A119_Q0.5451.00
190_N196_F0.5431.00
256_S259_S0.5421.00
32_L42_S0.5411.00
43_F46_L0.5411.00
72_A158_T0.5391.00
157_E225_P0.5391.00
196_F199_I0.5381.00
123_N143_L0.5361.00
194_L198_I0.5341.00
77_N81_I0.5321.00
265_I268_V0.5301.00
217_F220_R0.5291.00
102_V106_P0.5291.00
22_L26_N0.5271.00
94_T98_I0.5261.00
218_S221_I0.5251.00
268_V271_I0.5241.00
210_S214_L0.5221.00
111_S115_A0.5221.00
144_T234_P0.5211.00
34_W41_P0.5211.00
92_S178_K0.5201.00
100_L174_M0.5201.00
114_Y160_A0.5181.00
73_V218_S0.5171.00
60_L67_V0.5171.00
245_I258_L0.5151.00
31_L46_L0.5131.00
176_V181_I0.5131.00
57_F233_N0.5101.00
57_F61_A0.5091.00
8_M12_G0.5031.00
99_Y103_F0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquM 1 0.9474 100 0.295 Contact Map
2onkC 2 0.8772 100 0.301 Contact Map
3d31C 2 0.8702 100 0.304 Contact Map
3rlfF 1 0.9298 100 0.339 Contact Map
3rlfG 1 0.9404 100 0.344 Contact Map
4tquN 1 0.8877 100 0.367 Contact Map
4ymuD 2 0.7544 99.9 0.482 Contact Map
3tuiA 2 0.7333 99.9 0.516 Contact Map
2m20A 2 0.1333 9.5 0.947 Contact Map
2l2tA 2 0.1404 3.4 0.957 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0105 seconds.