GREMLIN Database
Q97UF3 - Arabinose ABC transporter, permease
UniProt: Q97UF3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 295 (254)
Sequences: 68082 (44822)
Seq/√Len: 2812.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
197_T201_R4.0541.00
84_L88_L3.2531.00
189_R198_I3.1251.00
174_S178_P3.0541.00
81_P84_L2.6881.00
82_T244_A2.6711.00
42_G66_Y2.6421.00
110_V185_I2.5801.00
194_G197_T2.5401.00
92_P158_I2.5231.00
188_A198_I2.5081.00
239_L247_F2.5071.00
185_I203_V2.4791.00
96_L162_L2.4771.00
176_F210_G2.4651.00
67_A71_F2.4571.00
80_E84_L2.3941.00
64_D67_A2.3931.00
195_D198_I2.3291.00
94_V215_L2.2931.00
64_D68_F2.2581.00
173_M211_F2.2431.00
196_W200_W2.2271.00
255_I258_R2.1311.00
197_T200_W2.0341.00
193_A197_T2.0301.00
102_T199_L2.0181.00
169_S214_T1.9681.00
109_F178_P1.9491.00
184_L206_L1.9321.00
177_L207_I1.9101.00
188_A193_A1.9101.00
40_L44_K1.8961.00
36_Y40_L1.8691.00
102_T207_I1.8471.00
123_F174_S1.8351.00
98_V215_L1.8231.00
81_P85_R1.7631.00
189_R195_D1.7501.00
185_I198_I1.7101.00
236_P239_L1.6991.00
90_A219_F1.6951.00
88_L92_P1.6841.00
101_G169_S1.6631.00
102_T173_M1.6511.00
104_T170_A1.6331.00
68_F258_R1.6321.00
93_S222_I1.6211.00
185_I189_R1.5821.00
108_F170_A1.5571.00
182_K185_I1.5261.00
68_F71_F1.5131.00
244_A248_Y1.5031.00
21_E25_A1.4961.00
33_V37_A1.4831.00
118_I121_G1.4521.00
226_F230_L1.4461.00
39_I264_V1.4441.00
78_G81_P1.4371.00
63_L67_A1.4281.00
169_S218_V1.4201.00
62_S65_A1.4071.00
89_V240_M1.3961.00
109_F174_S1.3951.00
213_S217_F1.3851.00
204_F211_F1.3731.00
177_L203_V1.3501.00
99_V103_M1.3371.00
37_A41_G1.3361.00
97_S218_V1.3341.00
279_R282_I1.3291.00
173_M214_T1.3261.00
105_A173_M1.3201.00
233_T238_M1.3071.00
182_K186_E1.2991.00
112_S119_S1.2801.00
226_F246_R1.2751.00
154_Y238_M1.2601.00
110_V182_K1.2551.00
102_T211_F1.2451.00
228_I232_L1.2411.00
188_A202_V1.2321.00
68_F72_G1.2251.00
183_Y186_E1.2241.00
121_G124_S1.2231.00
248_Y255_I1.2221.00
95_L99_V1.2171.00
145_E156_G1.2161.00
239_L244_A1.2101.00
48_E60_K1.2041.00
160_A232_L1.2041.00
106_Y177_L1.1931.00
92_P95_L1.1841.00
86_Y241_L1.1841.00
98_V211_F1.1821.00
15_I19_L1.1801.00
247_F251_A1.1691.00
25_A29_I1.1661.00
14_S18_A1.1621.00
180_V206_L1.1611.00
85_R88_L1.1601.00
248_Y253_A1.1591.00
194_G198_I1.1531.00
45_S48_E1.1511.00
157_L229_P1.1371.00
16_K20_L1.1171.00
208_F212_L1.1141.00
38_M264_V1.1091.00
158_I162_L1.1011.00
96_L158_I1.0871.00
121_G125_I1.0861.00
173_M210_G1.0811.00
150_V155_I1.0731.00
240_M243_V1.0651.00
37_A40_L1.0561.00
185_I195_D1.0471.00
109_F177_L1.0381.00
206_L209_P1.0381.00
18_A22_I1.0361.00
239_L243_V1.0341.00
93_S97_S1.0321.00
166_V170_A1.0311.00
275_I279_R1.0311.00
92_P96_L1.0291.00
225_E228_I1.0271.00
106_Y195_D1.0221.00
87_L91_I1.0141.00
106_Y199_L1.0101.00
78_G236_P1.0101.00
235_T238_M1.0061.00
93_S161_M1.0031.00
172_L214_T0.9981.00
70_W80_E0.9881.00
229_P240_M0.9851.00
198_I201_R0.9821.00
66_Y264_V0.9821.00
119_S178_P0.9801.00
103_M107_F0.9791.00
17_Y21_E0.9631.00
244_A262_A0.9611.00
193_A198_I0.9571.00
15_I18_A0.9521.00
95_L215_L0.9411.00
42_G46_N0.9381.00
141_L232_L0.9301.00
93_S158_I0.9291.00
18_A21_E0.9271.00
72_G78_G0.9271.00
20_L24_A0.9261.00
83_L241_L0.9231.00
28_V32_L0.9221.00
225_E229_P0.9211.00
244_A247_F0.9151.00
230_L243_V0.9091.00
279_R283_R0.8931.00
270_P274_F0.8911.00
105_A109_F0.8901.00
176_F207_I0.8871.00
91_I95_L0.8861.00
161_M222_I0.8851.00
44_K48_E0.8821.00
47_L50_A0.8821.00
97_S101_G0.8751.00
46_N50_A0.8691.00
88_L91_I0.8691.00
143_E147_S0.8641.00
249_T259_S0.8631.00
108_F123_F0.8611.00
69_A265_I0.8591.00
117_I120_N0.8551.00
141_L160_A0.8531.00
120_N123_F0.8531.00
101_G170_A0.8531.00
276_F280_Y0.8521.00
200_W204_F0.8521.00
208_F211_F0.8491.00
41_G44_K0.8481.00
246_R250_A0.8481.00
83_L87_L0.8411.00
41_G260_F0.8391.00
207_I210_G0.8391.00
43_L61_P0.8351.00
199_L204_F0.8351.00
198_I203_V0.8331.00
127_A171_L0.8331.00
96_L99_V0.8331.00
134_I164_F0.8321.00
79_L262_A0.8311.00
142_I146_T0.8271.00
152_N235_T0.8241.00
169_S173_M0.8221.00
173_M207_I0.8221.00
160_A228_I0.8201.00
105_A170_A0.8171.00
84_L87_L0.8141.00
89_V161_M0.8101.00
92_P162_L0.8081.00
65_A257_N0.8031.00
272_I276_F0.8001.00
248_Y262_A0.7921.00
146_T151_Y0.7921.00
88_L154_Y0.7851.00
208_F280_Y0.7801.00
218_V222_I0.7781.00
195_D199_L0.7761.00
38_M260_F0.7751.00
41_G45_S0.7741.00
138_T227_F0.7721.00
184_L202_V0.7671.00
248_Y258_R0.7661.00
260_F264_V0.7591.00
43_L62_S0.7581.00
280_Y283_R0.7551.00
156_G160_A0.7541.00
138_T231_I0.7471.00
61_P64_D0.7431.00
77_P81_P0.7401.00
97_S165_Y0.7361.00
98_V173_M0.7311.00
97_S169_S0.7311.00
105_A177_L0.7301.00
108_F174_S0.7291.00
45_S60_K0.7281.00
180_V207_I0.7271.00
104_T166_V0.7261.00
97_S222_I0.7261.00
82_T85_R0.7211.00
67_A70_W0.7191.00
68_F255_I0.7161.00
33_V36_Y0.7131.00
38_M263_G0.7121.00
241_L266_S0.7091.00
199_L203_V0.7091.00
173_M177_L0.7061.00
211_F214_T0.7021.00
89_V157_L0.7011.00
193_A201_R0.6991.00
94_V219_F0.6981.00
90_A94_V0.6981.00
108_F122_L0.6961.00
82_T241_L0.6961.00
150_V153_T0.6951.00
266_S270_P0.6951.00
100_I166_V0.6921.00
243_V247_F0.6901.00
65_A68_F0.6891.00
127_A130_T0.6881.00
72_G77_P0.6841.00
182_K189_R0.6831.00
271_L275_I0.6831.00
187_S191_D0.6821.00
165_Y221_Q0.6811.00
137_V163_I0.6801.00
134_I227_F0.6801.00
258_R262_A0.6781.00
80_E83_L0.6781.00
19_L22_I0.6731.00
22_I25_A0.6701.00
62_S66_Y0.6691.00
157_L233_T0.6681.00
48_E59_S0.6681.00
225_E240_M0.6671.00
28_V31_W0.6651.00
27_L31_W0.6651.00
101_G173_M0.6641.00
203_V206_L0.6621.00
89_V158_I0.6581.00
118_I122_L0.6571.00
233_T239_L0.6571.00
94_V98_V0.6531.00
44_K58_P0.6521.00
245_A262_A0.6521.00
104_T126_M0.6521.00
165_Y218_V0.6511.00
34_P38_M0.6501.00
77_P80_E0.6481.00
45_S59_S0.6421.00
157_L161_M0.6391.00
210_G214_T0.6381.00
86_Y242_P0.6371.00
63_L66_Y0.6361.00
211_F215_L0.6361.00
19_L23_I0.6361.00
17_Y20_L0.6321.00
143_E146_T0.6301.00
187_S190_M0.6151.00
69_A258_R0.6121.00
229_P243_V0.6111.00
24_A28_V0.6091.00
172_L210_G0.6071.00
126_M167_P0.6061.00
14_S17_Y0.6061.00
277_L280_Y0.6021.00
141_L144_L0.6011.00
100_I162_L0.6011.00
107_F111_L0.5981.00
123_F171_L0.5981.00
242_P266_S0.5971.00
60_K64_D0.5961.00
69_A262_A0.5921.00
117_I121_G0.5911.00
29_I33_V0.5901.00
90_A222_I0.5891.00
256_Y260_F0.5861.00
260_F263_G0.5841.00
145_E151_Y0.5841.00
151_Y154_Y0.5831.00
227_F230_L0.5811.00
89_V93_S0.5811.00
212_L215_L0.5811.00
200_W203_V0.5801.00
30_M34_P0.5791.00
41_G46_N0.5781.00
23_I27_L0.5771.00
124_S128_L0.5761.00
135_E231_I0.5751.00
97_S162_L0.5741.00
105_A174_S0.5731.00
272_I275_I0.5731.00
130_T168_T0.5711.00
78_G244_A0.5701.00
32_L36_Y0.5701.00
98_V102_T0.5691.00
120_N124_S0.5691.00
42_G261_A0.5651.00
198_I202_V0.5641.00
104_T107_F0.5641.00
180_V185_I0.5631.00
161_M225_E0.5611.00
161_M164_F0.5611.00
257_N260_F0.5601.00
220_L224_N0.5601.00
258_R261_A0.5591.00
215_L218_V0.5581.00
122_L126_M0.5561.00
112_S117_I0.5551.00
86_Y223_W0.5521.00
130_T167_P0.5521.00
90_A223_W0.5521.00
44_K60_K0.5491.00
85_R238_M0.5461.00
150_V154_Y0.5461.00
106_Y203_V0.5451.00
44_K59_S0.5451.00
66_Y261_A0.5441.00
243_V246_R0.5431.00
256_Y259_S0.5431.00
227_F231_I0.5431.00
125_I129_A0.5421.00
222_I225_E0.5411.00
156_G232_L0.5401.00
67_A72_G0.5391.00
129_A167_P0.5391.00
269_I272_I0.5371.00
164_F167_P0.5371.00
34_P39_I0.5361.00
144_L151_Y0.5361.00
221_Q224_N0.5351.00
138_T142_I0.5351.00
71_F77_P0.5331.00
93_S162_L0.5331.00
85_R240_M0.5321.00
34_P41_G0.5311.00
45_S49_A0.5311.00
34_P37_A0.5261.00
123_F178_P0.5241.00
194_G200_W0.5221.00
275_I278_G0.5201.00
45_S62_S0.5191.00
134_I138_T0.5171.00
21_E24_A0.5141.00
254_L257_N0.5091.00
94_V99_V0.5091.00
34_P42_G0.5061.00
89_V154_Y0.5061.00
111_L195_D0.5051.00
16_K19_L0.5051.00
34_P46_N0.5021.00
106_Y110_V0.5021.00
42_G264_V0.5011.00
187_S193_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquN 1 0.9119 100 0.297 Contact Map
3rlfG 1 0.9186 100 0.306 Contact Map
2onkC 2 0.8203 100 0.329 Contact Map
3d31C 2 0.8034 100 0.355 Contact Map
4tquM 1 0.8814 100 0.367 Contact Map
3rlfF 1 0.9051 100 0.419 Contact Map
4ymuD 2 0.7254 99.9 0.51 Contact Map
3tuiA 2 0.7153 99.9 0.546 Contact Map
2kogA 1 0.1356 8.5 0.952 Contact Map
2m8rA 1 0.1322 8.2 0.953 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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