GREMLIN Database
Q97UF2 - Arabinose ABC transporter, ATP-binding protein
UniProt: Q97UF2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 371 (310)
Sequences: 17490 (12857)
Seq/√Len: 730.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
225_G229_E4.2051.00
63_Y70_A4.0321.00
37_G210_A3.8631.00
5_R29_T3.6421.00
8_N25_N3.6371.00
34_M212_K3.5101.00
7_E63_Y3.4831.00
128_E133_S3.3021.00
21_K24_D3.1321.00
120_E124_K2.9481.00
222_A236_T2.7311.00
24_D220_K2.6991.00
226_T229_E2.5911.00
36_F214_G2.4771.00
7_E65_Y2.4721.00
10_S21_K2.4571.00
115_P118_K2.4191.00
102_F106_A2.3971.00
5_R65_Y2.3901.00
8_N27_S2.3781.00
102_F120_E2.3431.00
6_V9_L2.3361.00
31_D34_M2.3151.00
10_S61_S2.3061.00
102_F137_N2.2981.00
135_V138_R2.2931.00
12_I21_K2.2921.00
122_K160_D2.2231.00
10_S25_N2.2091.00
85_G162_K2.1931.00
11_K52_L2.1911.00
102_F124_K2.1201.00
187_K191_E2.1131.00
131_G180_S2.0351.00
65_Y70_A2.0231.00
67_D162_K2.0011.00
4_I163_V1.9741.00
9_L59_P1.9581.00
52_L59_P1.9081.00
14_K19_E1.8551.00
214_G221_F1.8471.00
127_S136_L1.8361.00
23_V52_L1.8301.00
121_N125_E1.8121.00
50_L199_V1.8101.00
214_G224_I1.8001.00
237_D279_V1.7941.00
217_V222_A1.7861.00
53_I197_L1.7831.00
11_K60_T1.6641.00
118_K121_N1.6491.00
122_K125_E1.6481.00
51_R57_E1.6051.00
207_F228_T1.6011.00
126_V158_V1.5891.00
11_K57_E1.5821.00
52_L64_I1.5681.00
117_D121_N1.5511.00
106_A123_V1.5031.00
246_I249_I1.5031.00
70_A73_S1.5001.00
3_T29_T1.4891.00
166_L196_T1.4881.00
265_V268_N1.4831.00
303_V319_V1.4761.00
71_V79_M1.4751.00
237_D241_R1.4601.00
6_V28_I1.4541.00
125_E128_E1.4521.00
228_T232_E1.4481.00
26_V49_F1.4471.00
114_V118_K1.4301.00
12_I60_T1.4251.00
102_F123_V1.4181.00
258_A261_A1.4011.00
237_D248_L1.4001.00
248_L279_V1.3711.00
69_E162_K1.3641.00
36_F224_I1.3591.00
66_F71_V1.3441.00
252_K277_N1.3391.00
114_V119_I1.3341.00
262_N265_V1.3341.00
6_V53_I1.3271.00
130_L154_A1.3151.00
124_K128_E1.3131.00
10_S24_D1.3071.00
99_M107_F1.3061.00
30_I36_F1.3051.00
6_V49_F1.3021.00
59_P64_I1.3011.00
106_A119_I1.3001.00
118_K122_K1.2991.00
79_M83_K1.2801.00
36_F212_K1.2761.00
309_S312_A1.2671.00
241_R248_L1.2661.00
3_T32_S1.2591.00
273_K276_S1.2391.00
100_T103_D1.2381.00
50_L165_L1.2371.00
229_E233_Y1.2301.00
100_T139_Y1.2201.00
306_K320_S1.2201.00
28_I214_G1.2071.00
103_D106_A1.2061.00
125_E160_D1.2031.00
69_E79_M1.2021.00
23_V49_F1.1901.00
215_V230_I1.1861.00
255_E258_A1.1851.00
189_Q194_L1.1761.00
7_E27_S1.1681.00
250_Q277_N1.1591.00
119_I123_V1.1551.00
301_G304_K1.1541.00
189_Q196_T1.1521.00
124_K136_L1.1411.00
3_T31_D1.1411.00
12_I61_S1.1351.00
310_Y313_G1.1251.00
87_A156_A1.1211.00
186_R209_I1.1171.00
31_D212_K1.1101.00
309_S313_G1.1091.00
103_D110_K1.1011.00
23_V26_V1.1001.00
246_I250_Q1.0951.00
63_Y72_S1.0921.00
125_E191_E1.0921.00
304_K307_L1.0891.00
246_I281_G1.0871.00
125_E129_E1.0691.00
80_S83_K1.0681.00
49_F216_I1.0641.00
265_V269_N1.0621.00
12_I19_E1.0611.00
247_N250_Q1.0571.00
110_K116_K1.0551.00
101_V143_L1.0531.00
263_L266_P1.0511.00
212_K224_I1.0451.00
65_Y68_N1.0431.00
12_I22_A1.0321.00
251_A278_I1.0291.00
312_A315_F1.0101.00
9_L52_L1.0091.00
34_M211_N1.0081.00
290_S294_L1.0041.00
28_I224_I1.0031.00
44_H216_I0.9991.00
263_L268_N0.9961.00
98_N141_K0.9931.00
307_L310_Y0.9921.00
33_G193_K0.9911.00
186_R190_R0.9841.00
266_P269_N0.9831.00
116_K120_E0.9781.00
200_S206_I0.9781.00
315_F318_V0.9741.00
272_L276_S0.9721.00
124_K133_S0.9621.00
303_V306_K0.9561.00
96_Y108_P0.9561.00
290_S293_L0.9501.00
306_K309_S0.9481.00
59_P72_S0.9421.00
108_P159_K0.9421.00
99_M103_D0.9411.00
13_F22_A0.9391.00
32_S67_D0.9381.00
264_K267_L0.9371.00
105_I154_A0.9361.00
263_L267_L0.9321.00
3_T67_D0.9281.00
258_A262_N0.9281.00
170_F185_V0.9181.00
5_R68_N0.9141.00
250_Q279_V0.9141.00
306_K310_Y0.9081.00
129_E191_E0.9051.00
39_L215_V0.9041.00
51_R56_L0.9041.00
6_V64_I0.9031.00
221_F224_I0.9011.00
302_I305_V0.8921.00
72_S79_M0.8901.00
247_N251_A0.8861.00
9_L64_I0.8851.00
139_Y142_E0.8851.00
105_I158_V0.8801.00
104_N155_R0.8801.00
30_I195_T0.8791.00
96_Y99_M0.8791.00
35_A196_T0.8781.00
160_D194_L0.8751.00
112_A159_K0.8741.00
54_A165_L0.8731.00
227_P231_Y0.8721.00
8_N61_S0.8711.00
215_V239_I0.8681.00
160_D191_E0.8641.00
315_F320_S0.8641.00
313_G316_K0.8631.00
87_A161_P0.8591.00
32_S162_K0.8571.00
107_F111_L0.8531.00
309_S314_I0.8521.00
105_I108_P0.8501.00
33_G195_T0.8491.00
291_D294_L0.8461.00
246_I251_A0.8431.00
106_A110_K0.8391.00
95_L140_P0.8361.00
35_A209_I0.8311.00
305_V312_A0.8301.00
231_Y285_D0.8291.00
312_A319_V0.8271.00
313_G318_V0.8231.00
127_S132_L0.8231.00
314_I318_V0.8221.00
38_V214_G0.8201.00
277_N281_G0.8201.00
311_G314_I0.8191.00
297_Y300_M0.8181.00
264_K268_N0.8161.00
64_I71_V0.8131.00
178_R202_D0.8111.00
217_V238_L0.8081.00
256_N261_A0.8071.00
312_A317_I0.7991.00
308_V311_G0.7941.00
186_R208_A0.7911.00
262_N267_L0.7911.00
37_G206_I0.7901.00
116_K119_I0.7881.00
179_E183_A0.7841.00
275_Q278_I0.7821.00
272_L275_Q0.7771.00
126_V157_L0.7741.00
308_V317_I0.7721.00
102_F136_L0.7711.00
120_E123_V0.7691.00
217_V220_K0.7681.00
52_L57_E0.7681.00
304_K320_S0.7611.00
79_M82_E0.7581.00
7_E29_T0.7581.00
184_L187_K0.7501.00
127_S133_S0.7481.00
256_N259_I0.7471.00
313_G320_S0.7471.00
315_F319_V0.7471.00
35_A189_Q0.7421.00
309_S317_I0.7401.00
260_I263_L0.7401.00
291_D295_D0.7381.00
114_V117_D0.7331.00
47_T51_R0.7331.00
303_V312_A0.7291.00
168_E201_H0.7291.00
302_I309_S0.7281.00
308_V312_A0.7281.00
14_K21_K0.7191.00
305_V308_V0.7191.00
162_K194_L0.7161.00
261_A265_V0.7161.00
52_L60_T0.7111.00
298_I301_G0.7081.00
311_G316_K0.7071.00
38_V216_I0.7071.00
282_L287_L0.7061.00
66_F86_I0.7061.00
305_V309_S0.7051.00
41_P44_H0.7041.00
293_L297_Y0.7021.00
126_V130_L0.7021.00
312_A316_K0.7011.00
153_I166_L0.6991.00
138_R142_E0.6961.00
259_I264_K0.6951.00
271_E274_G0.6951.00
38_V49_F0.6941.00
164_L194_L0.6941.00
282_L285_D0.6891.00
281_G284_P0.6881.00
161_P164_L0.6851.00
110_K119_I0.6841.00
175_A179_E0.6831.00
316_K320_S0.6831.00
176_Q241_R0.6811.00
306_K313_G0.6801.00
284_P288_T0.6791.00
38_V197_L0.6781.00
305_V310_Y0.6771.00
44_H49_F0.6761.00
304_K309_S0.6761.00
175_A182_R0.6761.00
257_N260_I0.6751.00
102_F119_I0.6721.00
126_V129_E0.6721.00
86_I163_V0.6711.00
309_S318_V0.6681.00
26_V221_F0.6631.00
257_N261_A0.6621.00
301_G309_S0.6621.00
311_G315_F0.6591.00
181_A184_L0.6591.00
179_E245_E0.6571.00
308_V316_K0.6571.00
101_V151_T0.6571.00
285_D289_L0.6551.00
284_P290_S0.6541.00
232_E310_Y0.6521.00
170_F198_I0.6521.00
313_G319_V0.6521.00
270_M273_K0.6511.00
300_M303_V0.6481.00
198_I210_A0.6481.00
140_P151_T0.6461.00
259_I262_N0.6461.00
204_A208_A0.6421.00
279_V283_R0.6401.00
95_L104_N0.6401.00
298_I302_I0.6361.00
199_V203_P0.6331.00
12_I24_D0.6331.00
316_K319_V0.6301.00
254_I259_I0.6261.00
225_G230_I0.6261.00
108_P155_R0.6241.00
3_T68_N0.6231.00
313_G321_P0.6221.00
188_I194_L0.6211.00
309_S316_K0.6191.00
290_S295_D0.6171.00
124_K132_L0.6161.00
93_W172_N0.6151.00
157_L192_R0.6151.00
85_G112_A0.6141.00
312_A318_V0.6141.00
264_K269_N0.6121.00
274_G277_N0.6121.00
262_N266_P0.6101.00
318_V321_P0.6101.00
254_I257_N0.6091.00
100_T137_N0.6081.00
34_M224_I0.6061.00
54_A88_M0.6051.00
87_A159_K0.6041.00
262_N268_N0.6041.00
87_A196_T0.6031.00
91_Q172_N0.6011.00
312_A321_P0.5991.00
293_L296_K0.5991.00
248_L251_A0.5981.00
273_K277_N0.5971.00
258_A263_L0.5971.00
105_I127_S0.5971.00
163_V195_T0.5971.00
294_L297_Y0.5961.00
13_F57_E0.5951.00
212_K223_Q0.5951.00
234_P239_I0.5941.00
206_I210_A0.5941.00
165_L197_L0.5941.00
301_G305_V0.5931.00
310_Y315_F0.5921.00
314_I317_I0.5901.00
253_I256_N0.5861.00
259_I263_L0.5851.00
6_V26_V0.5851.00
312_A320_S0.5851.00
123_V126_V0.5841.00
24_D218_N0.5821.00
129_E157_L0.5811.00
314_I319_V0.5801.00
131_G134_G0.5791.00
21_K25_N0.5771.00
253_I278_I0.5771.00
260_I264_K0.5751.00
185_V196_T0.5751.00
104_N140_P0.5741.00
166_L198_I0.5741.00
298_I306_K0.5731.00
270_M274_G0.5711.00
268_N271_E0.5701.00
227_P230_I0.5701.00
255_E259_I0.5691.00
216_I221_F0.5691.00
239_I243_T0.5671.00
85_G159_K0.5661.00
314_I320_S0.5641.00
278_I281_G0.5641.00
307_L313_G0.5631.00
310_Y314_I0.5621.00
129_E187_K0.5611.00
153_I209_I0.5601.00
171_S175_A0.5601.00
179_E204_A0.5571.00
164_L196_T0.5561.00
11_K48_T0.5551.00
114_V122_K0.5521.00
303_V321_P0.5511.00
115_P119_I0.5501.00
254_I274_G0.5491.00
258_A265_V0.5481.00
189_Q211_N0.5461.00
25_N61_S0.5451.00
172_N182_R0.5451.00
178_R205_D0.5451.00
284_P291_D0.5451.00
249_I253_I0.5441.00
267_L270_M0.5411.00
96_Y159_K0.5401.00
308_V315_F0.5391.00
316_K321_P0.5391.00
238_L242_L0.5381.00
249_I252_K0.5371.00
30_I197_L0.5371.00
229_E232_E0.5351.00
35_A198_I0.5341.00
289_L292_T0.5341.00
180_S184_L0.5331.00
267_L271_E0.5321.00
255_E274_G0.5311.00
183_A187_K0.5311.00
303_V310_Y0.5301.00
182_R208_A0.5291.00
231_Y234_P0.5291.00
292_T295_D0.5261.00
247_N255_E0.5251.00
71_V86_I0.5251.00
289_L293_L0.5241.00
134_G147_Q0.5241.00
304_K312_A0.5241.00
240_A244_G0.5231.00
132_L135_V0.5231.00
280_I284_P0.5221.00
271_E275_Q0.5221.00
199_V202_D0.5211.00
284_P287_L0.5211.00
310_Y319_V0.5201.00
263_L269_N0.5191.00
304_K311_G0.5191.00
311_G320_S0.5161.00
99_M104_N0.5151.00
308_V313_G0.5151.00
189_Q192_R0.5151.00
200_S205_D0.5151.00
301_G312_A0.5121.00
147_Q177_I0.5101.00
311_G318_V0.5101.00
273_K278_I0.5101.00
239_I242_L0.5091.00
302_I306_K0.5081.00
102_F105_I0.5081.00
188_I192_R0.5081.00
13_F48_T0.5071.00
206_I213_A0.5061.00
310_Y316_K0.5051.00
89_V156_A0.5051.00
299_D302_I0.5030.99
256_N260_I0.5030.99
238_L241_R0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1v43A 2 0.9218 100 0.198 Contact Map
1oxxK 1 0.9407 100 0.2 Contact Map
2it1A 1 0.9542 100 0.203 Contact Map
2yyzA 1 0.9434 100 0.205 Contact Map
1g291 4 0.965 100 0.207 Contact Map
3rlfA 2 0.9596 100 0.22 Contact Map
3fvqA 2 0.9407 100 0.225 Contact Map
1z47A 2 0.9218 100 0.235 Contact Map
3d31A 2 0.9111 100 0.244 Contact Map
3tuiC 2 0.9137 100 0.245 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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