GREMLIN Database
ILVD - Dihydroxy-acid dehydratase
UniProt: Q97UB2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 558 (542)
Sequences: 4706 (1860)
Seq/√Len: 79.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
405_E503_V4.4731.00
495_I524_L4.3591.00
253_L258_F3.9491.00
256_E338_H3.7381.00
389_P492_P3.5031.00
405_E514_K3.4981.00
503_V514_K3.4831.00
495_I520_I3.4771.00
428_E462_N3.3461.00
259_E338_H3.3321.00
405_E501_T3.2521.00
248_K251_E3.1761.00
505_D508_S3.1441.00
497_E526_R3.0681.00
116_G243_I3.0681.00
496_V513_L2.9141.00
332_L339_G2.7981.00
339_G350_K2.7951.00
177_T180_E2.7791.00
501_T514_K2.7011.00
138_N250_R2.6901.00
390_E550_S2.6901.00
138_N251_E2.6451.00
38_V116_G2.6361.00
368_R372_N2.6131.00
409_K430_E2.5921.00
503_V512_D2.5471.00
253_L257_A2.4961.00
135_A253_L2.4541.00
409_K498_D2.4401.00
407_K501_T2.4291.00
345_T352_N2.4051.00
497_E519_E2.3991.00
292_D384_K2.3671.00
440_K489_V2.3411.00
516_S519_E2.3411.00
131_L213_M2.3331.00
213_M253_L2.3201.00
519_E522_N2.3141.00
238_A241_S2.2961.00
144_I235_T2.2861.00
170_A175_R2.2851.00
386_S512_D2.2731.00
264_T328_L2.2661.00
263_T300_R2.2361.00
142_I239_L2.2301.00
162_E474_A2.2161.00
413_S416_D2.2121.00
466_V483_V2.2031.00
220_S315_M2.1981.00
295_N299_K2.1921.00
256_E340_D2.1761.00
24_R186_K2.1641.00
403_K505_D2.1291.00
515_L520_I2.1231.00
263_T301_T2.1221.00
262_I294_F2.1041.00
392_A511_L2.1031.00
131_L281_I2.0931.00
412_N435_R2.0901.00
24_R30_D2.0851.00
347_K351_Q2.0741.00
266_M297_I2.0601.00
341_V349_M2.0251.00
150_E224_T1.9801.00
517_E521_K1.9631.00
402_V507_E1.9551.00
255_F259_E1.9201.00
238_A245_N1.9161.00
38_V243_I1.9051.00
290_T293_D1.8961.00
295_N509_E1.8841.00
234_E237_K1.8801.00
522_N525_K1.8691.00
171_Y176_I1.8531.00
522_N526_R1.8521.00
387_L496_V1.8261.00
70_L240_G1.8251.00
513_L520_I1.8141.00
142_I238_A1.8071.00
171_Y178_E1.8041.00
527_W530_P1.8021.00
119_G141_S1.8001.00
208_S214_A1.7871.00
227_R319_D1.7851.00
259_E296_R1.7811.00
496_V502_I1.7781.00
241_S244_E1.7311.00
520_I524_L1.7271.00
328_L349_M1.7241.00
381_V509_E1.7131.00
348_T351_Q1.7131.00
412_N416_D1.7131.00
135_A285_A1.7131.00
496_V515_L1.7031.00
403_K507_E1.6681.00
328_L353_L1.6611.00
134_M141_S1.6581.00
67_E237_K1.6481.00
521_K525_K1.6421.00
419_K423_S1.6381.00
116_G239_L1.6351.00
540_A544_S1.6221.00
65_T70_L1.6121.00
214_A218_S1.6091.00
531_S535_K1.6041.00
263_T297_I1.5991.00
404_F407_K1.5981.00
241_S245_N1.5941.00
109_F117_L1.5891.00
262_I289_L1.5851.00
151_P316_A1.5741.00
66_K72_P1.5681.00
203_T270_G1.5641.00
412_N436_Y1.5611.00
176_I180_E1.5591.00
142_I344_V1.5500.99
40_I65_T1.5470.99
210_A264_T1.5340.99
56_A229_V1.5310.99
492_P520_I1.5250.99
410_V496_V1.4930.99
403_K503_V1.4840.99
293_D296_R1.4760.99
407_K430_E1.4700.99
48_G79_V1.4660.99
411_Y425_E1.4580.99
260_N341_V1.4550.99
242_L247_I1.4510.99
299_K377_R1.4510.99
411_Y420_G1.4480.99
60_V233_K1.4460.99
218_S231_Y1.4430.99
296_R300_R1.4400.99
484_A550_S1.4330.99
424_G458_A1.4310.99
330_K333_D1.4290.99
420_G426_V1.4280.99
30_D182_Y1.4260.99
313_Y365_H1.4210.99
255_F293_D1.4190.99
408_A502_I1.4190.99
59_R63_E1.4170.99
42_T74_A1.4110.99
132_M284_E1.3920.99
32_E35_K1.3900.99
61_A118_V1.3730.99
58_A120_I1.3720.99
154_F180_E1.3720.99
521_K524_L1.3670.99
42_T73_L1.3640.99
347_K352_N1.3530.99
256_E259_E1.3490.99
213_M249_S1.3480.99
515_L519_E1.3460.99
41_A108_Q1.3350.98
28_L73_L1.3270.98
283_Y551_M1.3270.98
408_A496_V1.3080.98
63_E66_K1.3040.98
318_L327_V1.3030.98
416_D419_K1.2980.98
353_L356_Y1.2980.98
80_V111_A1.2950.98
275_V279_L1.2880.98
334_A370_V1.2880.98
203_T274_A1.2870.98
512_D517_E1.2870.98
46_E62_K1.2830.98
306_S312_D1.2740.98
133_A249_S1.2670.98
38_V65_T1.2660.98
278_L289_L1.2620.98
54_T122_G1.2570.98
65_T236_G1.2530.98
60_V229_V1.2470.98
330_K364_S1.2440.98
252_I257_A1.2400.97
64_G236_G1.2340.97
131_L208_S1.2200.97
253_L285_A1.2150.97
255_F296_R1.2140.97
210_A328_L1.2110.97
118_V239_L1.2100.97
403_K508_S1.2100.97
432_V455_I1.2000.97
39_A109_F1.1970.97
47_A114_F1.1960.97
361_V364_S1.1940.97
364_S372_N1.1850.97
183_E187_R1.1850.97
292_D296_R1.1850.97
160_T314_V1.1820.97
415_D419_K1.1810.97
258_F281_I1.1760.97
55_L59_R1.1700.96
495_I515_L1.1680.96
390_E484_A1.1670.96
138_N248_K1.1660.96
386_S517_E1.1620.96
433_I502_I1.1600.96
303_Y375_K1.1560.96
135_A213_M1.1560.96
337_L349_M1.1560.96
547_S551_M1.1560.96
37_L73_L1.1520.96
409_K427_S1.1510.96
433_I496_V1.1490.96
484_A548_Q1.1480.96
288_K551_M1.1450.96
39_A117_L1.1440.96
332_L337_L1.1430.96
67_E233_K1.1410.96
410_V498_D1.1390.96
520_I523_R1.1380.96
495_I527_W1.1360.96
155_M180_E1.1340.96
394_I504_I1.1290.96
17_A164_V1.1290.96
415_D446_P1.1290.96
41_A117_L1.1290.96
133_A137_L1.1290.96
78_M104_M1.1280.96
118_V236_G1.1250.96
348_T352_N1.1170.95
28_L71_S1.1160.95
242_L245_N1.1120.95
145_Y218_S1.1090.95
60_V63_E1.1050.95
44_W55_L1.0950.95
30_D186_K1.0950.95
409_K420_G1.0910.95
532_P535_K1.0900.95
456_M461_N1.0890.95
493_I496_V1.0880.95
119_G143_Y1.0850.95
20_R185_E1.0740.94
182_Y186_K1.0730.94
464_A504_I1.0710.94
159_L184_I1.0710.94
332_L350_K1.0670.94
64_G67_E1.0660.94
220_S319_D1.0640.94
255_F288_K1.0620.94
369_D372_N1.0610.94
153_Y158_R1.0610.94
390_E551_M1.0590.94
105_V133_A1.0550.94
56_A59_R1.0510.94
382_I393_V1.0510.94
492_P513_L1.0480.93
92_R446_P1.0430.93
259_E293_D1.0390.93
430_E498_D1.0380.93
329_K356_Y1.0370.93
351_Q354_E1.0350.93
221_P225_S1.0340.93
494_A527_W1.0320.93
155_M183_E1.0270.93
121_G127_T1.0240.93
548_Q551_M1.0190.92
23_L26_V1.0140.92
412_N497_E1.0130.92
251_E342_L1.0110.92
390_E548_Q1.0080.92
18_P168_I1.0050.92
381_V507_E1.0050.92
386_S513_L1.0020.92
407_K427_S1.0000.92
63_E233_K1.0000.92
332_L353_L0.9960.92
515_L524_L0.9950.92
216_P352_N0.9920.91
452_T471_F0.9920.91
25_S49_P0.9900.91
409_K426_V0.9860.91
329_K355_Q0.9860.91
524_L527_W0.9850.91
238_A242_L0.9850.91
349_M352_N0.9830.91
276_L279_L0.9790.91
119_G134_M0.9790.91
437_E446_P0.9770.91
43_A130_I0.9700.90
211_L258_F0.9670.90
150_E225_S0.9660.90
428_E458_A0.9650.90
456_M479_M0.9560.90
334_A371_K0.9510.90
150_E191_T0.9480.89
427_S430_E0.9430.89
247_I342_L0.9430.89
88_S112_H0.9420.89
387_L492_P0.9420.89
33_I71_S0.9380.89
426_V432_V0.9370.89
265_L274_A0.9340.89
316_A320_E0.9330.89
492_P524_L0.9270.88
329_K333_D0.9270.88
433_I513_L0.9240.88
191_T226_S0.9220.88
538_L555_T0.9210.88
490_G527_W0.9190.88
268_M327_V0.9190.88
221_P231_Y0.9170.88
542_Y546_V0.9160.88
93_Y110_N0.9140.88
532_P540_A0.9110.88
252_I342_L0.9110.88
329_K332_L0.9100.87
383_L392_A0.9090.87
154_F184_I0.9050.87
226_S230_M0.9000.87
335_G370_V0.8990.87
480_V504_I0.8980.87
332_L354_E0.8960.87
533_R537_G0.8920.86
63_E67_E0.8910.86
142_I235_T0.8880.86
103_D541_K0.8870.86
211_L261_A0.8860.86
215_L238_A0.8850.86
14_I171_Y0.8830.86
101_I129_G0.8820.86
401_V404_F0.8810.86
255_F287_V0.8770.85
257_A342_L0.8740.85
54_T146_G0.8690.85
301_T336_L0.8690.85
364_S369_D0.8660.85
35_K71_S0.8660.85
100_L107_A0.8660.85
100_L538_L0.8630.85
213_M252_I0.8630.85
431_V502_I0.8610.84
58_A74_A0.8590.84
405_E512_D0.8580.84
321_V364_S0.8570.84
426_V498_D0.8550.84
214_A235_T0.8550.84
541_K545_L0.8550.84
62_K74_A0.8540.84
230_M234_E0.8520.84
306_S313_Y0.8520.84
312_D365_H0.8510.84
518_E522_N0.8490.84
53_H146_G0.8480.83
41_A105_V0.8470.83
513_L516_S0.8470.83
52_F192_L0.8460.83
70_L236_G0.8450.83
434_I437_E0.8450.83
159_L163_D0.8440.83
394_I506_V0.8420.83
37_L71_S0.8400.83
304_I370_V0.8390.83
146_G194_T0.8360.83
135_A258_F0.8340.82
299_K509_E0.8330.82
421_V451_V0.8320.82
24_R33_I0.8310.82
409_K425_E0.8300.82
236_G239_L0.8270.82
246_G249_S0.8200.81
247_I251_E0.8140.81
150_E222_T0.8120.81
35_K67_E0.8110.81
105_V130_I0.8100.81
536_S540_A0.8070.80
503_V510_R0.8060.80
321_V361_V0.8060.80
350_K354_E0.8040.80
64_G233_K0.8040.80
121_G143_Y0.8030.80
264_T324_V0.8020.80
404_F431_V0.8010.80
227_R230_M0.7990.80
330_K371_K0.7980.80
328_L337_L0.7980.80
118_V144_I0.7980.80
332_L335_G0.7980.80
250_R286_G0.7970.80
80_V107_A0.7940.79
238_A247_I0.7880.79
240_G243_I0.7870.79
141_S249_S0.7850.78
342_L352_N0.7830.78
242_L344_V0.7830.78
217_G319_D0.7780.78
207_M265_L0.7770.78
318_L367_V0.7770.78
81_N85_G0.7750.78
161_I165_H0.7750.78
263_T336_L0.7750.78
254_T257_A0.7730.77
79_V126_T0.7720.77
436_Y494_A0.7690.77
40_I62_K0.7690.77
40_I61_A0.7680.77
43_A77_T0.7680.77
29_T32_E0.7680.77
381_V396_V0.7670.77
515_L523_R0.7670.77
42_T54_T0.7660.77
349_M353_L0.7630.76
341_V348_T0.7620.76
350_K353_L0.7620.76
306_S368_R0.7620.76
158_R316_A0.7600.76
283_Y288_K0.7590.76
39_A114_F0.7580.76
89_E534_Y0.7560.76
483_V493_I0.7540.76
433_I483_V0.7530.76
239_L243_I0.7530.76
466_V496_V0.7530.76
65_T118_V0.7520.75
295_N381_V0.7520.75
342_L347_K0.7510.75
80_V94_S0.7510.75
475_T479_M0.7500.75
256_E341_V0.7480.75
528_S531_S0.7470.75
206_S268_M0.7460.75
131_L253_L0.7460.75
517_E520_I0.7440.75
157_K180_E0.7430.75
333_D350_K0.7430.75
107_A538_L0.7430.75
258_F287_V0.7420.74
229_V233_K0.7410.74
442_A446_P0.7400.74
339_G353_L0.7390.74
342_L345_T0.7380.74
247_I352_N0.7380.74
541_K555_T0.7380.74
426_V430_E0.7350.74
387_L435_R0.7340.74
418_F450_R0.7340.74
297_I300_R0.7330.74
160_T474_A0.7320.73
412_N530_P0.7310.73
480_V483_V0.7280.73
198_L268_M0.7280.73
547_S554_V0.7260.73
445_M549_A0.7240.73
300_R336_L0.7240.73
135_A249_S0.7240.73
232_V235_T0.7230.73
43_A121_G0.7210.72
160_T164_V0.7210.72
384_K390_E0.7200.72
11_Y37_L0.7200.72
154_F183_E0.7200.72
515_L521_K0.7190.72
135_A257_A0.7180.72
50_C81_N0.7180.72
178_E182_Y0.7180.72
36_P70_L0.7180.72
206_S219_A0.7150.72
340_D350_K0.7140.72
412_N498_D0.7130.72
145_Y205_G0.7130.72
494_A530_P0.7120.71
406_G431_V0.7110.71
121_G130_I0.7110.71
527_W531_S0.7090.71
394_I478_P0.7090.71
275_V294_F0.7080.71
68_A236_G0.7060.71
54_T58_A0.7060.71
41_A75_F0.7050.71
117_L141_S0.7040.71
535_K540_A0.7030.70
530_P533_R0.7020.70
387_L512_D0.6970.70
145_Y228_R0.6970.70
401_V478_P0.6940.69
40_I117_L0.6940.69
305_A327_V0.6910.69
267_A304_I0.6910.69
163_D474_A0.6900.69
532_P537_G0.6900.69
283_Y554_V0.6900.69
516_S522_N0.6900.69
489_V548_Q0.6890.69
65_T239_L0.6890.69
138_N249_S0.6880.69
16_N19_H0.6880.69
411_Y426_V0.6870.69
142_I242_L0.6870.69
250_R536_S0.6860.69
167_A184_I0.6840.68
86_M197_G0.6810.68
338_H341_V0.6800.68
64_G68_A0.6790.68
387_L513_L0.6780.68
170_A180_E0.6760.67
416_D420_G0.6720.67
341_V350_K0.6710.67
488_M546_V0.6690.67
45_S108_Q0.6690.67
153_Y156_G0.6690.67
407_K431_V0.6690.67
505_D510_R0.6680.67
313_Y366_I0.6680.67
257_A287_V0.6680.67
61_A120_I0.6660.66
425_E430_E0.6640.66
68_A240_G0.6640.66
516_S520_I0.6640.66
213_M254_T0.6600.66
517_E523_R0.6600.66
149_A189_H0.6600.66
291_L550_S0.6600.66
422_Q474_A0.6590.65
259_E340_D0.6570.65
407_K503_V0.6560.65
221_P319_D0.6560.65
154_F176_I0.6560.65
55_L74_A0.6550.65
286_G536_S0.6550.65
160_T163_D0.6550.65
295_N298_S0.6540.65
506_V509_E0.6530.65
336_L370_V0.6530.65
29_T33_I0.6520.65
258_F289_L0.6520.65
275_V393_V0.6520.65
262_I278_L0.6500.64
310_G397_A0.6500.64
207_M211_L0.6500.64
170_A176_I0.6500.64
87_G450_R0.6500.64
417_A432_V0.6490.64
242_L252_I0.6480.64
289_L294_F0.6480.64
31_E234_E0.6480.64
48_G108_Q0.6480.64
489_V527_W0.6470.64
347_K355_Q0.6470.64
519_E523_R0.6470.64
235_T239_L0.6470.64
165_H197_G0.6450.64
60_V64_G0.6450.64
253_L289_L0.6440.64
257_A285_A0.6430.64
410_V513_L0.6420.63
13_G16_N0.6420.63
23_L33_I0.6410.63
208_S281_I0.6400.63
77_T104_M0.6400.63
32_E237_K0.6370.63
282_A287_V0.6370.63
250_R285_A0.6360.63
64_G237_K0.6360.63
437_E442_A0.6360.63
230_M233_K0.6350.63
502_I513_L0.6350.63
171_Y177_T0.6350.63
117_L137_L0.6330.62
23_L28_L0.6310.62
38_V239_L0.6310.62
207_M278_L0.6300.62
537_G540_A0.6290.62
240_G244_E0.6290.62
365_H368_R0.6280.62
326_V367_V0.6280.62
222_T319_D0.6280.62
109_F139_V0.6270.62
399_T478_P0.6270.62
427_S460_L0.6270.62
325_P352_N0.6260.62
192_L224_T0.6260.62
310_G398_A0.6260.62
507_E510_R0.6260.62
425_E498_D0.6240.61
252_I343_T0.6230.61
518_E521_K0.6220.61
431_V464_A0.6220.61
489_V550_S0.6210.61
18_P165_H0.6200.61
51_N149_A0.6200.61
488_M529_P0.6190.61
381_V394_I0.6190.61
262_I297_I0.6190.61
428_E460_L0.6180.61
345_T348_T0.6180.61
307_M318_L0.6180.61
166_E476_R0.6170.60
55_L62_K0.6150.60
47_A108_Q0.6150.60
335_G339_G0.6150.60
263_T331_L0.6140.60
45_S79_V0.6140.60
399_T506_V0.6140.60
77_T130_I0.6130.60
210_A324_V0.6130.60
43_A79_V0.6120.60
365_H372_N0.6120.60
512_D515_L0.6120.60
210_A341_V0.6110.60
164_V188_A0.6100.60
339_G354_E0.6090.59
46_E74_A0.6090.59
295_N377_R0.6080.59
166_E169_G0.6080.59
299_K381_V0.6080.59
151_P196_S0.6070.59
100_L104_M0.6070.59
24_R182_Y0.6060.59
89_E110_N0.6060.59
213_M257_A0.6040.59
217_G325_P0.6040.59
268_M318_L0.6020.59
39_A75_F0.6010.58
490_G495_I0.6010.58
164_V184_I0.6010.58
233_K237_K0.6000.58
377_R402_V0.5970.58
228_R231_Y0.5970.58
21_A164_V0.5960.58
57_L120_I0.5960.58
19_H87_G0.5960.58
333_D371_K0.5950.58
40_I58_A0.5940.58
387_L493_I0.5930.57
59_R62_K0.5930.57
254_T341_V0.5930.57
26_V52_F0.5930.57
153_Y320_E0.5920.57
171_Y181_L0.5900.57
241_S247_I0.5900.57
225_S319_D0.5890.57
96_V538_L0.5890.57
25_S30_D0.5890.57
17_A181_L0.5880.57
12_H34_G0.5880.57
122_G146_G0.5870.57
418_F454_A0.5870.57
135_A250_R0.5860.56
303_Y397_A0.5860.56
304_I368_R0.5840.56
191_T224_T0.5830.56
231_Y235_T0.5830.56
206_S315_M0.5830.56
238_A344_V0.5820.56
139_V249_S0.5820.56
110_N113_A0.5810.56
154_F159_L0.5810.56
420_G425_E0.5800.56
303_Y374_I0.5800.56
266_M298_S0.5800.56
329_K357_K0.5800.56
162_E308_K0.5790.56
75_F108_Q0.5790.56
208_S213_M0.5790.56
330_K370_V0.5790.56
234_E238_A0.5780.55
66_K71_S0.5770.55
546_V553_A0.5740.55
421_V454_A0.5740.55
321_V367_V0.5720.55
464_A478_P0.5720.55
196_S308_K0.5720.55
176_I184_I0.5700.54
407_K513_L0.5700.54
85_G88_S0.5700.54
57_L60_V0.5690.54
26_V71_S0.5690.54
42_T199_F0.5690.54
243_I246_G0.5690.54
272_T482_H0.5660.54
295_N384_K0.5660.54
404_F478_P0.5660.54
50_C126_T0.5650.54
40_I74_A0.5650.54
263_T338_H0.5620.53
262_I290_T0.5610.53
420_G498_D0.5610.53
41_A79_V0.5610.53
234_E241_S0.5600.53
172_L422_Q0.5600.53
290_T296_R0.5600.53
333_D339_G0.5600.53
521_K526_R0.5590.53
210_A337_L0.5590.53
419_K425_E0.5590.53
36_P240_G0.5580.53
205_G219_A0.5570.53
51_N81_N0.5560.53
269_G397_A0.5560.53
168_I181_L0.5560.53
469_G553_A0.5560.53
453_A457_G0.5550.53
434_I475_T0.5530.52
416_D425_E0.5520.52
23_L73_L0.5520.52
191_T225_S0.5510.52
136_R284_E0.5500.52
245_N251_E0.5490.52
329_K353_L0.5490.52
217_G221_P0.5490.52
196_S314_V0.5490.52
24_R230_M0.5480.52
61_A239_L0.5480.52
501_T513_L0.5470.51
330_K369_D0.5470.51
45_S76_P0.5460.51
375_K402_V0.5450.51
515_L522_N0.5440.51
408_A431_V0.5440.51
289_L292_D0.5440.51
504_I511_L0.5430.51
394_I399_T0.5430.51
94_S449_L0.5420.51
343_T352_N0.5420.51
105_V119_G0.5420.51
39_A108_Q0.5410.51
267_A301_T0.5410.51
134_M143_Y0.5410.51
524_L528_S0.5400.51
38_V376_P0.5390.50
326_V364_S0.5390.50
275_V382_I0.5380.50
540_A545_L0.5380.50
345_T351_Q0.5370.50
205_G228_R0.5370.50
304_I327_V0.5360.50
121_G189_H0.5360.50
341_V352_N0.5360.50
180_E183_E0.5350.50
327_V367_V0.5350.50
242_L251_E0.5350.50
169_G457_G0.5330.50
253_L281_I0.5330.50
381_V506_V0.5330.50
331_L337_L0.5320.50
239_L242_L0.5310.49
207_M219_A0.5310.49
109_F114_F0.5310.49
23_L84_I0.5310.49
487_A493_I0.5300.49
197_G449_L0.5300.49
179_N183_E0.5300.49
435_R494_A0.5300.49
151_P317_D0.5290.49
386_S492_P0.5280.49
409_K416_D0.5270.49
304_I330_K0.5260.49
46_E52_F0.5260.49
294_F382_I0.5260.49
523_R526_R0.5260.49
218_S228_R0.5260.49
418_F422_Q0.5260.49
104_M108_Q0.5250.49
159_L162_E0.5250.49
474_A479_M0.5250.49
39_A73_L0.5240.48
259_E289_L0.5240.48
143_Y218_S0.5240.48
139_V433_I0.5230.48
76_P120_I0.5220.48
44_W58_A0.5220.48
313_Y374_I0.5210.48
411_Y498_D0.5210.48
255_F338_H0.5210.48
57_L64_G0.5200.48
53_H223_A0.5200.48
279_L484_A0.5200.48
303_Y378_G0.5200.48
404_F464_A0.5200.48
95_L445_M0.5190.48
85_G94_S0.5180.48
86_M199_F0.5180.48
129_G143_Y0.5170.48
257_A278_L0.5170.48
497_E513_L0.5160.47
89_E92_R0.5140.47
222_T225_S0.5140.47
219_A222_T0.5140.47
15_Y172_L0.5140.47
168_I450_R0.5130.47
164_V167_A0.5130.47
41_A76_P0.5120.47
86_M165_H0.5120.47
291_L391_G0.5120.47
148_S228_R0.5110.47
357_K362_P0.5110.47
407_K425_E0.5110.47
409_K428_E0.5110.47
434_I451_V0.5110.47
78_M108_Q0.5100.47
265_L270_G0.5090.47
254_T287_V0.5090.47
65_T240_G0.5090.47
290_T550_S0.5080.46
145_Y214_A0.5080.46
141_S213_M0.5060.46
306_S374_I0.5060.46
54_T74_A0.5050.46
466_V502_I0.5050.46
11_Y73_L0.5040.46
89_E113_A0.5040.46
490_G524_L0.5030.46
17_A20_R0.5030.46
207_M261_A0.5020.46
61_A65_T0.5020.46
494_A513_L0.5010.46
163_D197_G0.5010.46
222_T316_A0.5000.45
396_V506_V0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gp4A 2 0.8584 100 0.098 Contact Map
3rfqA 5 0.2384 73.1 0.981 Contact Map
3wryA 1 0.3799 67.7 0.982 Contact Map
2pcnA 3 0.2527 66 0.982 Contact Map
1j3lA 3 0.2581 63 0.983 Contact Map
1nxjA 3 0.2419 62.4 0.983 Contact Map
4lhbA 4 0.2366 62.3 0.983 Contact Map
3nojA 5 0.362 61.8 0.983 Contact Map
1vi4A 1 0.2509 60.7 0.983 Contact Map
2is8A 3 0.2509 54.5 0.984 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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