GREMLIN Database
AGAL - Alpha-galactosidase
UniProt: Q97U94 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 648 (554)
Sequences: 414 (225)
Seq/√Len: 9.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
566_K587_E5.9671.00
296_K303_V5.5361.00
324_L352_A5.0461.00
292_V303_V4.5580.99
474_V498_A3.4960.96
304_G363_L3.4290.96
230_N483_T3.2330.94
422_N441_N3.1000.93
422_N448_T3.0800.93
267_D275_R2.9900.92
138_L505_V2.8980.90
198_I447_L2.8540.90
267_D276_S2.7790.88
194_I446_L2.7710.88
247_K611_V2.7160.87
302_Y362_D2.6700.86
307_H354_D2.6220.85
603_E625_T2.6150.85
246_V259_V2.5850.84
288_F292_V2.5790.84
308_A368_N2.5700.84
469_H473_R2.3560.78
369_Q428_P2.3230.77
237_L483_T2.3200.77
287_G305_L2.3140.77
292_V361_F2.2870.76
361_F435_K2.2750.75
529_L544_F2.2740.75
316_M475_F2.2610.75
97_T103_L2.2500.75
261_I303_V2.2450.74
148_F184_I2.2190.73
108_K163_D2.2120.73
313_W404_M2.1620.71
460_M471_V2.1610.71
544_F589_V2.1390.71
229_W306_W2.1380.71
456_Y477_G2.0920.69
564_Y589_V2.0620.68
162_G166_R2.0480.67
349_F629_V2.0430.67
446_L579_V2.0400.67
260_I363_L2.0280.66
316_M564_Y2.0080.65
434_T468_V2.0050.65
92_D603_E2.0050.65
238_N309_I1.9450.63
361_F385_S1.9300.62
96_V109_S1.9270.62
300_V502_N1.9110.61
424_I433_G1.9070.61
354_D395_S1.8800.60
151_L201_A1.8800.60
190_P519_L1.8690.60
233_L237_L1.8660.60
114_K583_E1.8650.59
316_M556_Y1.8610.59
582_R585_D1.8570.59
290_N294_A1.8560.59
306_W457_D1.8510.59
306_W437_H1.8390.58
231_A526_E1.8350.58
256_L395_S1.8310.58
320_L341_P1.8110.57
256_L361_F1.8090.57
306_W458_M1.7850.56
113_E138_L1.7620.55
163_D542_I1.7090.53
366_V392_L1.6970.52
211_R511_P1.6950.52
120_P480_I1.6860.52
369_Q437_H1.6740.51
481_Y503_G1.6730.51
92_D95_P1.6620.51
324_L438_I1.6600.50
111_D249_I1.6590.50
284_F477_G1.6590.50
300_V397_G1.6490.50
294_A616_N1.6350.49
97_T511_P1.6320.49
230_N237_L1.6200.49
240_E244_K1.6190.49
421_R457_D1.6110.48
363_L536_V1.6060.48
307_H456_Y1.5990.48
151_L447_L1.5980.48
472_A487_P1.5960.48
307_H545_F1.5840.47
428_P437_H1.5840.47
102_E105_Y1.5740.47
198_I451_I1.5520.46
133_Y339_P1.5480.45
421_R458_M1.5450.45
96_V108_K1.5410.45
87_N90_A1.5360.45
233_L408_P1.5350.45
447_L475_F1.5240.44
403_C423_S1.5120.44
441_N478_G1.5000.43
241_N354_D1.4870.43
125_P428_P1.4810.42
475_F603_E1.4770.42
297_S611_V1.4730.42
306_W421_R1.4640.42
123_L406_M1.4610.42
114_K585_D1.4500.41
310_N368_N1.4480.41
364_V442_A1.4460.41
602_R627_L1.4450.41
320_L323_S1.4430.41
102_E393_Q1.4400.41
262_D306_W1.4350.40
414_Y420_M1.4310.40
313_W437_H1.4210.40
502_N565_Y1.4150.40
444_N593_P1.4070.39
150_T517_D1.4050.39
228_S469_H1.3950.39
167_L556_Y1.3920.39
427_V433_G1.3780.38
185_G196_N1.3740.38
405_S420_M1.3730.38
578_N611_V1.3680.38
138_L190_P1.3680.38
463_D488_E1.3680.38
400_V417_S1.3630.37
265_W473_R1.3620.37
97_T104_K1.3590.37
228_S490_T1.3590.37
351_K491_N1.3540.37
309_I372_I1.3490.37
217_P231_A1.3480.37
187_S192_K1.3380.36
103_L106_D1.3360.36
494_L605_I1.3360.36
329_Y332_N1.3360.36
309_I346_A1.3310.36
85_Y108_K1.3310.36
471_V545_F1.3280.36
194_I449_S1.3280.36
129_N569_S1.3250.36
480_I553_E1.3230.36
229_W457_D1.3230.36
305_L424_I1.3220.36
365_K457_D1.3180.36
308_A456_Y1.3160.35
268_Q586_A1.3160.35
367_D457_D1.3060.35
365_K425_D1.3020.35
134_T138_L1.3000.35
453_Y480_I1.2920.34
260_I358_L1.2890.34
367_D458_M1.2880.34
404_M437_H1.2870.34
265_W424_I1.2860.34
264_G274_I1.2840.34
150_T160_L1.2810.34
456_Y460_M1.2800.34
139_V309_I1.2670.33
397_G422_N1.2650.33
120_P123_L1.2640.33
367_D455_D1.2640.33
405_S426_Y1.2590.33
95_P556_Y1.2590.33
365_K458_M1.2530.33
147_A480_I1.2510.33
190_P354_D1.2510.33
229_W458_M1.2500.33
305_L361_F1.2490.33
506_I591_T1.2490.33
398_K442_A1.2490.33
341_P447_L1.2360.32
527_R611_V1.2350.32
613_V641_E1.2290.32
324_L627_L1.2270.32
140_K268_Q1.2250.32
229_W437_H1.2210.32
227_C457_D1.2200.32
403_C428_P1.2190.32
295_I352_A1.2180.32
187_S500_L1.2170.31
239_E309_I1.2040.31
226_W230_N1.2030.31
557_N613_V1.1980.31
98_E104_K1.1960.31
306_W365_K1.1890.30
146_E277_L1.1870.30
84_T97_T1.1870.30
313_W367_D1.1870.30
122_W263_D1.1850.30
400_V581_L1.1820.30
471_V543_A1.1810.30
393_Q483_T1.1760.30
306_W367_D1.1750.30
230_N456_Y1.1750.30
98_E102_E1.1720.30
247_K251_E1.1720.30
129_N292_V1.1690.30
169_T316_M1.1680.30
477_G545_F1.1640.29
230_N233_L1.1580.29
84_T108_K1.1520.29
539_Y544_F1.1510.29
268_Q443_Y1.1500.29
359_R640_R1.1470.29
158_A244_K1.1450.29
633_E638_K1.1450.29
177_K611_V1.1410.29
152_S587_E1.1330.28
194_I450_H1.1320.28
227_C458_M1.1290.28
178_R569_S1.1280.28
254_L566_K1.1260.28
151_L468_V1.1260.28
287_G479_P1.1250.28
611_V617_V1.1240.28
359_R564_Y1.1230.28
193_A291_T1.1170.28
292_V296_K1.1140.28
408_P412_C1.1120.28
349_F485_R1.1060.27
302_Y316_M1.1060.27
98_E107_I1.1050.27
145_Y520_F1.1040.27
289_K493_E1.1030.27
575_G578_N1.1030.27
367_D404_M1.1020.27
512_A519_L1.1000.27
424_I427_V1.1000.27
260_I411_Y1.0970.27
178_R348_G1.0930.27
221_M419_V1.0930.27
599_I602_R1.0920.27
427_V465_Y1.0900.27
266_Q454_P1.0860.27
532_L595_S1.0860.27
236_D244_K1.0840.27
559_N619_I1.0820.27
284_F287_G1.0790.26
563_Y592_F1.0750.26
122_W125_P1.0740.26
267_D372_I1.0710.26
442_A456_Y1.0700.26
92_D579_V1.0620.26
209_K577_F1.0610.26
202_S213_E1.0600.26
241_N395_S1.0570.26
249_I487_P1.0520.25
284_F307_H1.0510.25
283_K307_H1.0500.25
280_D283_K1.0490.25
227_C306_W1.0460.25
230_N245_V1.0430.25
118_T121_C1.0400.25
363_L472_A1.0400.25
306_W313_W1.0370.25
87_N92_D1.0330.25
150_T264_G1.0320.25
590_I618_V1.0300.25
367_D421_R1.0300.25
411_Y423_S1.0280.25
95_P103_L1.0280.25
103_L142_G1.0250.25
180_Y587_E1.0230.25
114_K478_G1.0210.24
206_F563_Y1.0190.24
421_R581_L1.0190.24
407_N461_S1.0160.24
437_H457_D1.0140.24
393_Q410_N1.0120.24
267_D620_P1.0120.24
175_E329_Y1.0110.24
249_I255_R1.0100.24
354_D456_Y1.0070.24
227_C423_S1.0070.24
325_N621_K1.0050.24
216_F453_Y1.0050.24
593_P624_G1.0050.24
239_E243_I1.0050.24
433_G524_L1.0050.24
231_A283_K1.0020.24
265_W456_Y0.9990.24
350_Y477_G0.9980.24
567_V584_L0.9970.24
151_L579_V0.9950.24
92_D104_K0.9950.24
169_T177_K0.9920.23
112_H131_P0.9910.23
148_F292_V0.9890.23
420_M426_Y0.9890.23
158_A289_K0.9850.23
491_N601_L0.9840.23
87_N580_K0.9840.23
284_F350_Y0.9810.23
153_N160_L0.9780.23
369_Q423_S0.9750.23
97_T100_P0.9750.23
460_M490_T0.9750.23
91_I100_P0.9750.23
495_L549_S0.9750.23
345_D589_V0.9740.23
455_D458_M0.9730.23
143_N285_P0.9720.23
98_E101_K0.9710.23
124_Y398_K0.9710.23
96_V259_V0.9710.23
496_R570_G0.9700.23
544_F610_T0.9700.23
391_A543_A0.9690.23
253_G342_N0.9690.23
425_D457_D0.9670.23
360_D479_P0.9670.23
233_L483_T0.9660.23
232_F241_N0.9660.23
369_Q403_C0.9640.23
475_F537_K0.9640.23
229_W262_D0.9630.23
310_N372_I0.9630.23
358_L557_N0.9630.23
184_I581_L0.9630.23
577_F589_V0.9630.23
121_C135_V0.9620.23
245_V353_F0.9610.23
285_P405_S0.9580.22
366_V406_M0.9560.22
228_S471_V0.9550.22
198_I406_M0.9540.22
441_N476_S0.9510.22
260_I423_S0.9510.22
183_S547_L0.9500.22
539_Y592_F0.9500.22
563_Y572_F0.9490.22
225_G439_M0.9490.22
465_Y482_I0.9480.22
355_G611_V0.9470.22
135_V230_N0.9470.22
288_F359_R0.9450.22
266_Q434_T0.9450.22
471_V586_A0.9440.22
130_I446_L0.9440.22
202_S305_L0.9430.22
570_G579_V0.9420.22
437_H458_M0.9420.22
365_K421_R0.9410.22
388_I490_T0.9400.22
493_E582_R0.9380.22
91_I95_P0.9380.22
217_P226_W0.9370.22
312_H627_L0.9350.22
227_C263_D0.9350.22
318_Q401_I0.9340.22
267_D531_K0.9280.21
438_I556_Y0.9280.21
96_V106_D0.9260.21
420_M452_V0.9250.21
263_D367_D0.9240.21
558_N562_Y0.9230.21
432_D619_I0.9220.21
94_E97_T0.9220.21
264_G283_K0.9210.21
437_H455_D0.9210.21
265_W530_L0.9200.21
231_A385_S0.9190.21
130_I240_E0.9190.21
229_W421_R0.9180.21
115_Y123_L0.9180.21
231_A303_V0.9160.21
228_S258_W0.9130.21
313_W457_D0.9130.21
395_S634_L0.9130.21
254_L371_V0.9090.21
124_Y605_I0.9080.21
425_D458_M0.9080.21
500_L522_D0.9080.21
341_P406_M0.9070.21
203_K289_K0.9070.21
438_I512_A0.9020.21
179_S637_V0.9000.21
230_N408_P0.8990.21
468_V497_M0.8970.21
346_A447_L0.8940.20
414_Y472_A0.8920.20
313_W458_M0.8920.20
92_D108_K0.8910.20
329_Y516_E0.8910.20
236_D563_Y0.8900.20
199_N480_I0.8880.20
323_S352_A0.8880.20
228_S459_F0.8860.20
194_I375_I0.8860.20
424_I434_T0.8850.20
187_S495_L0.8850.20
284_F545_F0.8840.20
325_N579_V0.8830.20
493_E567_V0.8830.20
254_L479_P0.8830.20
346_A420_M0.8820.20
361_F611_V0.8810.20
360_D413_N0.8810.20
370_W478_G0.8770.20
313_W455_D0.8760.20
148_F286_N0.8760.20
225_G363_L0.8750.20
175_E582_R0.8730.20
181_F282_K0.8720.20
160_L322_K0.8720.20
210_L213_E0.8710.20
226_W258_W0.8690.20
272_R440_F0.8670.20
619_I632_T0.8660.20
623_D640_R0.8620.20
169_T309_I0.8600.20
398_K475_F0.8590.19
443_Y609_F0.8580.19
306_W455_D0.8550.19
489_R553_E0.8550.19
412_C464_P0.8540.19
309_I316_M0.8530.19
307_H477_G0.8510.19
125_P285_P0.8500.19
354_D483_T0.8500.19
275_R319_E0.8500.19
293_R470_L0.8470.19
95_P489_R0.8450.19
456_Y534_G0.8430.19
206_F485_R0.8410.19
408_P483_T0.8410.19
456_Y473_R0.8370.19
122_W313_W0.8350.19
282_K292_V0.8350.19
97_T160_L0.8330.19
306_W425_D0.8320.19
260_I627_L0.8310.19
277_L478_G0.8310.19
472_A477_G0.8310.19
99_P105_Y0.8300.19
108_K596_N0.8280.19
372_I406_M0.8280.19
264_G268_Q0.8280.19
227_C403_C0.8280.19
130_I133_Y0.8260.19
303_V377_D0.8250.19
268_Q495_L0.8230.18
92_D97_T0.8220.18
404_M457_D0.8220.18
467_K497_M0.8210.18
392_L400_V0.8200.18
422_N461_S0.8180.18
267_D569_S0.8160.18
473_R530_L0.8130.18
125_P620_P0.8120.18
227_C421_R0.8110.18
131_P257_N0.8110.18
357_I424_I0.8100.18
350_Y460_M0.8090.18
158_A406_M0.8080.18
249_I546_N0.8070.18
432_D542_I0.8060.18
284_F484_D0.8050.18
577_F580_K0.8040.18
307_H601_L0.8040.18
190_P480_I0.8040.18
151_L309_I0.8040.18
265_W469_H0.8040.18
265_W426_Y0.8040.18
209_K579_V0.8030.18
152_S504_E0.8030.18
259_V509_D0.8020.18
181_F194_I0.8020.18
456_Y545_F0.8020.18
466_A491_N0.8020.18
294_A619_I0.8010.18
404_M458_M0.7990.18
239_E286_N0.7990.18
305_L434_T0.7990.18
310_N340_S0.7950.18
191_Y354_D0.7950.18
568_F585_D0.7940.18
374_A384_A0.7920.18
209_K599_I0.7910.18
296_K345_D0.7900.18
498_A508_V0.7890.18
283_K520_F0.7890.18
404_M455_D0.7890.18
423_S481_Y0.7870.18
456_Y463_D0.7850.17
363_L634_L0.7850.17
287_G478_G0.7840.17
579_V625_T0.7840.17
531_K593_P0.7820.17
277_L505_V0.7810.17
106_D589_V0.7790.17
277_L311_A0.7760.17
469_H601_L0.7760.17
220_V515_T0.7760.17
146_E575_G0.7750.17
95_P100_P0.7730.17
369_Q405_S0.7730.17
357_I456_Y0.7720.17
123_L408_P0.7720.17
216_F221_M0.7720.17
405_S588_V0.7720.17
308_A459_F0.7700.17
259_V599_I0.7700.17
408_P447_L0.7690.17
436_L440_F0.7680.17
90_A105_Y0.7660.17
568_F587_E0.7650.17
464_P602_R0.7650.17
162_G349_F0.7620.17
474_V605_I0.7620.17
289_K325_N0.7590.17
234_T317_S0.7560.17
288_F361_F0.7540.17
295_I494_L0.7530.17
164_S542_I0.7520.17
497_M605_I0.7520.17
441_N461_S0.7510.17
187_S193_A0.7490.17
104_K142_G0.7470.17
542_I616_N0.7470.17
362_D411_Y0.7460.16
262_D365_K0.7440.16
234_T408_P0.7430.16
246_V298_L0.7410.16
358_L398_K0.7410.16
148_F289_K0.7410.16
125_P436_L0.7410.16
283_K506_I0.7390.16
560_E611_V0.7380.16
224_L304_G0.7350.16
550_G557_N0.7350.16
408_P433_G0.7330.16
248_G544_F0.7330.16
122_W473_R0.7300.16
123_L487_P0.7280.16
157_T230_N0.7280.16
503_G593_P0.7270.16
483_T622_A0.7260.16
201_A637_V0.7250.16
436_L476_S0.7220.16
465_Y584_L0.7220.16
245_V252_R0.7220.16
89_L104_K0.7210.16
477_G481_Y0.7190.16
294_A618_V0.7180.16
339_P606_L0.7180.16
546_N593_P0.7170.16
245_V460_M0.7160.16
433_G451_I0.7140.16
238_N403_C0.7090.16
447_L493_E0.7090.16
229_W365_K0.7090.16
427_V434_T0.7070.16
148_F327_N0.7060.16
267_D292_V0.7060.16
122_W404_M0.7040.15
539_Y577_F0.7030.15
260_I304_G0.7020.15
388_I494_L0.7020.15
602_R611_V0.7010.15
284_F456_Y0.6990.15
148_F351_K0.6990.15
462_Y588_V0.6990.15
324_L529_L0.6980.15
535_K556_Y0.6970.15
421_R455_D0.6960.15
84_T94_E0.6940.15
97_T169_T0.6930.15
89_L579_V0.6930.15
183_S200_I0.6920.15
501_P530_L0.6890.15
151_L525_R0.6890.15
262_D367_D0.6880.15
167_L325_N0.6870.15
169_T181_F0.6850.15
420_M434_T0.6830.15
229_W367_D0.6810.15
262_D437_H0.6800.15
531_K534_G0.6790.15
395_S549_S0.6790.15
192_K359_R0.6780.15
403_C417_S0.6770.15
232_F314_G0.6770.15
249_I479_P0.6740.15
277_L588_V0.6730.15
399_D626_L0.6730.15
306_W404_M0.6730.15
456_Y608_P0.6680.15
208_F214_K0.6670.15
227_C367_D0.6640.15
388_I405_S0.6640.15
274_I474_V0.6630.15
422_N604_Y0.6630.15
347_I394_Y0.6620.15
357_I428_P0.6610.14
220_V635_N0.6610.14
150_T170_G0.6610.14
166_R194_I0.6600.14
361_F424_I0.6570.14
403_C457_D0.6570.14
282_K561_D0.6540.14
405_S414_Y0.6540.14
184_I289_K0.6530.14
163_D496_R0.6530.14
183_S197_A0.6510.14
487_P511_P0.6510.14
363_L606_L0.6500.14
319_E495_L0.6500.14
361_F420_M0.6490.14
225_G231_A0.6490.14
190_P395_S0.6480.14
191_Y449_S0.6480.14
341_P388_I0.6480.14
418_N543_A0.6470.14
263_D457_D0.6470.14
199_N621_K0.6460.14
118_T420_M0.6450.14
364_V543_A0.6440.14
405_S487_P0.6430.14
246_V251_E0.6430.14
516_E629_V0.6430.14
84_T91_I0.6420.14
133_Y384_A0.6410.14
312_H428_P0.6410.14
181_F491_N0.6390.14
426_Y434_T0.6380.14
130_I137_A0.6360.14
228_S312_H0.6360.14
142_G580_K0.6350.14
312_H421_R0.6340.14
259_V499_V0.6330.14
313_W421_R0.6320.14
292_V633_E0.6320.14
454_P469_H0.6310.14
95_P361_F0.6310.14
423_S479_P0.6300.14
306_W403_C0.6300.14
96_V387_N0.6290.14
534_G558_N0.6280.14
446_L619_I0.6280.14
317_S452_V0.6260.14
408_P428_P0.6250.14
289_K582_R0.6240.14
259_V417_S0.6230.14
295_I586_A0.6230.14
138_L510_E0.6220.14
461_S609_F0.6220.14
341_P402_N0.6210.14
522_D526_E0.6210.14
372_I491_N0.6200.14
263_D455_D0.6190.14
288_F545_F0.6190.14
200_I338_V0.6190.14
403_C452_V0.6190.14
263_D458_M0.6180.14
108_K571_E0.6180.14
238_N434_T0.6180.14
410_N417_S0.6160.14
410_N514_I0.6150.14
360_D365_K0.6150.14
442_A476_S0.6130.13
441_N473_R0.6130.13
162_G534_G0.6100.13
402_N405_S0.6090.13
186_T569_S0.6080.13
95_P615_D0.6080.13
140_K526_E0.6080.13
143_N558_N0.6070.13
155_Y293_R0.6070.13
217_P283_K0.6060.13
304_G608_P0.6050.13
246_V487_P0.6040.13
350_Y472_A0.6030.13
228_S252_R0.6020.13
125_P403_C0.6010.13
336_S476_S0.6000.13
321_M324_L0.6000.13
421_R437_H0.5990.13
403_C410_N0.5990.13
154_N247_K0.5990.13
167_L206_F0.5980.13
122_W265_W0.5980.13
350_Y412_C0.5970.13
402_N468_V0.5970.13
122_W367_D0.5960.13
121_C230_N0.5960.13
631_D634_L0.5950.13
187_S318_Q0.5940.13
206_F572_F0.5940.13
245_V368_N0.5920.13
344_E611_V0.5910.13
632_T636_E0.5900.13
167_L293_R0.5900.13
502_N594_K0.5890.13
167_L332_N0.5860.13
125_P423_S0.5850.13
227_C365_K0.5840.13
328_G331_T0.5840.13
421_R425_D0.5830.13
252_R490_T0.5820.13
596_N636_E0.5820.13
162_G554_E0.5810.13
316_M489_R0.5800.13
541_A622_A0.5790.13
245_V454_P0.5790.13
233_L517_D0.5780.13
95_P109_S0.5770.13
260_I447_L0.5770.13
169_T615_D0.5770.13
289_K293_R0.5770.13
101_K161_F0.5760.13
262_D455_D0.5760.13
262_D425_D0.5760.13
266_Q309_I0.5740.13
270_N283_K0.5740.13
542_I594_K0.5730.13
114_K118_T0.5720.13
156_V517_D0.5710.13
441_N469_H0.5680.13
224_L363_L0.5680.13
196_N555_E0.5660.13
119_Y370_W0.5660.13
468_V610_T0.5640.12
413_N611_V0.5630.12
85_Y106_D0.5630.12
241_N533_K0.5620.12
259_V375_I0.5620.12
304_G498_A0.5620.12
286_N290_N0.5620.12
88_Q91_I0.5610.12
265_W364_V0.5610.12
319_E635_N0.5600.12
256_L515_T0.5600.12
105_Y363_L0.5590.12
145_Y149_F0.5590.12
407_N497_M0.5580.12
288_F296_K0.5580.12
209_K574_V0.5550.12
312_H457_D0.5550.12
228_S360_D0.5540.12
125_P481_Y0.5530.12
327_N344_E0.5530.12
160_L579_V0.5520.12
86_Y89_L0.5510.12
233_L264_G0.5510.12
201_A291_T0.5510.12
188_D197_A0.5510.12
95_P611_V0.5500.12
189_N204_E0.5500.12
445_S626_L0.5490.12
188_D566_K0.5490.12
493_E571_E0.5480.12
403_C458_M0.5480.12
88_Q105_Y0.5480.12
277_L317_S0.5470.12
214_K526_E0.5470.12
106_D272_R0.5460.12
335_N585_D0.5460.12
92_D188_D0.5450.12
390_I562_Y0.5420.12
125_P288_F0.5420.12
264_G498_A0.5410.12
135_V217_P0.5400.12
237_L456_Y0.5400.12
433_G447_L0.5390.12
146_E578_N0.5380.12
424_I463_D0.5360.12
404_M421_R0.5350.12
149_F545_F0.5330.12
88_Q92_D0.5330.12
477_G608_P0.5320.12
186_T571_E0.5310.12
252_R406_M0.5310.12
350_Y388_I0.5300.12
243_I294_A0.5290.12
151_L618_V0.5290.12
559_N575_G0.5290.12
395_S515_T0.5290.12
319_E564_Y0.5280.12
166_R570_G0.5280.12
128_N194_I0.5260.12
303_V542_I0.5250.12
116_I126_V0.5240.12
160_L626_L0.5230.12
366_V474_V0.5210.12
143_N321_M0.5200.12
115_Y125_P0.5200.12
97_T105_Y0.5190.12
443_Y614_S0.5190.12
187_S297_S0.5190.12
242_L392_L0.5190.12
254_L478_G0.5180.12
215_G259_V0.5180.12
301_K438_I0.5180.12
556_Y589_V0.5170.12
595_S619_I0.5170.12
137_A592_F0.5170.12
270_N280_D0.5170.12
454_P471_V0.5150.12
295_I627_L0.5150.12
582_R611_V0.5140.12
306_W312_H0.5130.12
407_N410_N0.5120.11
117_R546_N0.5120.11
184_I573_G0.5120.11
174_D397_G0.5110.11
272_R480_I0.5110.11
99_P104_K0.5100.11
288_F428_P0.5100.11
97_T106_D0.5100.11
163_D178_R0.5090.11
424_I566_K0.5090.11
150_T406_M0.5080.11
376_Y426_Y0.5070.11
408_P441_N0.5070.11
518_L542_I0.5070.11
576_K599_I0.5050.11
246_V560_E0.5040.11
165_V172_N0.5040.11
263_D313_W0.5040.11
334_L398_K0.5040.11
164_S236_D0.5030.11
84_T101_K0.5030.11
244_K286_N0.5030.11
148_F636_E0.5030.11
116_I523_P0.5020.11
223_G257_N0.5020.11
154_N168_Y0.5010.11
263_D306_W0.5000.11
201_A212_K0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cc1A 4 0.5602 100 0.793 Contact Map
4nzfA 5 0.5679 100 0.802 Contact Map
3a21A 2 0.6188 100 0.812 Contact Map
1uasA 1 0.5185 100 0.822 Contact Map
3hg3A 2 0.5262 100 0.825 Contact Map
4nzjA 2 0.6512 100 0.826 Contact Map
3lrkA 3 0.5895 100 0.826 Contact Map
3a5vA 3 0.534 100 0.834 Contact Map
1sznA 1 0.5463 100 0.844 Contact Map
1zy9A 1 0.7315 100 0.854 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0147 seconds.