GREMLIN Database
Q97U61 - Glycolate oxidase iron-sulfur subunit. (GlcF)
UniProt: Q97U61 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 344 (334)
Sequences: 5865 (4046)
Seq/√Len: 221.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
245_T273_K4.5351.00
135_D162_K3.8971.00
233_I265_N3.7801.00
226_Y234_K3.6701.00
154_K340_D3.6691.00
245_T275_R3.4011.00
228_F339_A3.3891.00
171_C208_C2.7121.00
181_N184_G2.6921.00
244_D316_K2.6581.00
264_R276_E2.5241.00
155_A204_L2.4931.00
68_K71_Q2.3421.00
135_D199_K2.3391.00
318_I341_L2.3001.00
150_K340_D2.2211.00
250_Y264_R2.1951.00
142_C171_C2.1661.00
190_I194_E2.1561.00
172_C208_C2.1361.00
94_K97_A2.1201.00
138_L204_L2.1021.00
161_K231_F2.0861.00
136_I231_F2.0781.00
277_M309_I2.0481.00
87_E90_L2.0421.00
135_D164_K2.0231.00
134_G161_K2.0231.00
316_K336_Y1.9961.00
186_K190_I1.9691.00
203_T209_A1.9681.00
295_P299_D1.9561.00
144_E152_V1.9351.00
265_N268_E1.9161.00
278_E311_K1.8851.00
170_G191_R1.8661.00
226_Y230_E1.8611.00
246_F341_L1.8591.00
213_K230_E1.8441.00
151_T340_D1.8371.00
88_K91_E1.8341.00
142_C208_C1.8341.00
244_D315_K1.8171.00
127_P153_E1.7971.00
247_T277_M1.7621.00
264_R268_E1.7331.00
189_A215_Y1.7201.00
226_Y231_F1.7151.00
85_V90_L1.7111.00
26_V300_M1.7011.00
87_E92_N1.6921.00
100_L104_S1.6681.00
155_A228_F1.6451.00
15_G35_R1.6271.00
86_M91_E1.6181.00
89_M92_N1.6081.00
158_Y342_L1.5991.00
60_E68_K1.5791.00
267_A318_I1.5751.00
155_A159_L1.5691.00
87_E91_E1.5631.00
142_C172_C1.5571.00
78_K182_Y1.5551.00
247_T312_S1.5441.00
230_E259_L1.5161.00
200_K226_Y1.5001.00
97_A101_K1.4971.00
245_T315_K1.4921.00
122_N127_P1.4881.00
93_P97_A1.4841.00
112_V117_K1.4811.00
104_S107_N1.4791.00
156_Y163_Y1.4771.00
246_F316_K1.4701.00
230_E262_H1.4551.00
101_K104_S1.4521.00
85_V88_K1.4311.00
88_K92_N1.4191.00
246_F272_I1.4191.00
85_V92_N1.4131.00
30_E35_R1.3721.00
115_F118_F1.3671.00
93_P107_N1.3631.00
93_P101_K1.3471.00
176_H184_G1.3171.00
302_M306_R1.3161.00
104_S108_S1.3121.00
202_I231_F1.3071.00
174_L207_N1.2971.00
336_Y341_L1.2871.00
194_E197_K1.2821.00
200_K224_N1.2791.00
303_N310_A1.2761.00
246_F318_I1.2761.00
136_I202_I1.2751.00
232_L266_V1.2621.00
131_D162_K1.2591.00
86_M89_M1.2591.00
86_M90_L1.2561.00
100_L103_L1.2501.00
303_N307_G1.2441.00
307_G311_K1.2441.00
158_Y339_A1.2411.00
112_V119_V1.2331.00
177_I211_F1.2331.00
112_V115_F1.2251.00
101_K105_K1.2191.00
243_N273_K1.2171.00
95_L98_K1.2151.00
137_I199_K1.2101.00
200_K231_F1.2091.00
325_A335_V1.1991.00
224_N234_K1.1971.00
336_Y340_D1.1961.00
205_Q321_N1.1871.00
43_I47_S1.1851.00
128_L156_Y1.1771.00
177_I185_A1.1731.00
309_I328_I1.1721.00
103_L106_A1.1671.00
96_L100_L1.1661.00
302_M327_A1.1491.00
136_I163_Y1.1481.00
39_E42_R1.1421.00
18_L33_S1.1381.00
113_Q117_K1.1351.00
281_H305_K1.1351.00
112_V116_V1.1311.00
57_R60_E1.1271.00
232_L342_L1.1251.00
111_E117_K1.1161.00
133_E162_K1.1121.00
261_S264_R1.1091.00
106_A109_Y1.1051.00
248_V263_I1.1051.00
251_P319_V1.1011.00
309_I317_V1.0971.00
71_Q217_E1.0941.00
32_H52_T1.0801.00
97_A100_L1.0751.00
153_E157_K1.0701.00
100_L107_N1.0701.00
261_S265_N1.0691.00
203_T212_M1.0691.00
284_C324_C1.0691.00
317_V328_I1.0631.00
166_K169_N1.0611.00
234_K262_H1.0581.00
114_R117_K1.0551.00
110_P117_K1.0531.00
192_L215_Y1.0531.00
320_T338_I1.0441.00
188_L192_L1.0401.00
190_I222_E1.0401.00
132_G162_K1.0391.00
110_P113_Q1.0381.00
99_S102_L1.0381.00
37_R40_A1.0371.00
85_V91_E1.0371.00
141_G205_Q1.0321.00
250_Y276_E1.0311.00
97_A104_S1.0291.00
43_I46_N1.0271.00
259_L262_H1.0251.00
148_F151_T1.0221.00
242_V272_I1.0211.00
117_K121_P1.0201.00
111_E114_R1.0191.00
115_F119_V1.0171.00
80_S84_T1.0171.00
93_P98_K1.0161.00
101_K108_S1.0141.00
95_L104_S1.0131.00
195_K198_G1.0061.00
174_L178_S0.9981.00
20_T62_A0.9941.00
267_A272_I0.9891.00
96_L101_K0.9861.00
95_L101_K0.9841.00
116_V120_K0.9821.00
113_Q120_K0.9791.00
265_N269_K0.9781.00
103_L107_N0.9771.00
295_P330_S0.9761.00
101_K107_N0.9711.00
76_V80_S0.9701.00
38_I69_Y0.9671.00
310_A331_M0.9631.00
307_G310_A0.9621.00
177_I182_Y0.9611.00
131_D134_G0.9591.00
94_K98_K0.9591.00
228_F232_L0.9571.00
18_L24_Y0.9551.00
82_K183_E0.9521.00
262_H265_N0.9511.00
140_P169_N0.9491.00
124_V128_L0.9491.00
176_H188_L0.9481.00
26_V297_L0.9401.00
140_P152_V0.9401.00
233_I269_K0.9371.00
25_V304_V0.9361.00
289_D293_S0.9351.00
117_K125_S0.9311.00
250_Y260_V0.9301.00
26_V304_V0.9281.00
188_L191_R0.9271.00
111_E116_V0.9200.99
96_L107_N0.9190.99
268_E274_I0.9170.99
105_K108_S0.9150.99
184_G187_K0.9140.99
151_T154_K0.9140.99
94_K101_K0.9100.99
42_R46_N0.9080.99
296_K300_M0.9080.99
209_A213_K0.9010.99
78_K82_K0.8980.99
156_Y165_V0.8970.99
121_P126_E0.8940.99
86_M92_N0.8910.99
93_P96_L0.8900.99
155_A339_A0.8890.99
247_T309_I0.8870.99
102_L107_N0.8870.99
247_T317_V0.8870.99
18_L30_E0.8820.99
94_K107_N0.8780.99
193_A197_K0.8750.99
185_A211_F0.8740.99
60_E70_A0.8700.99
93_P102_L0.8690.99
277_M312_S0.8690.99
178_S207_N0.8670.99
39_E43_I0.8650.99
12_T18_L0.8640.99
153_E156_Y0.8630.99
110_P119_V0.8610.99
148_F322_S0.8600.99
23_T37_R0.8600.99
154_K158_Y0.8590.99
159_L202_I0.8560.99
36_G40_A0.8530.99
298_S327_A0.8510.99
209_A257_Q0.8500.99
123_E126_E0.8490.99
57_R70_A0.8480.99
35_R38_I0.8480.99
79_S83_K0.8480.99
310_A332_G0.8440.99
40_A49_G0.8410.99
286_A291_W0.8410.99
94_K104_S0.8390.99
115_F120_K0.8380.99
138_L144_E0.8370.99
50_F76_V0.8370.99
138_L155_A0.8360.99
96_L99_S0.8340.99
123_E127_P0.8330.99
189_A218_W0.8330.99
114_R119_V0.8290.99
79_S82_K0.8280.99
243_N271_G0.8260.99
117_K122_N0.8240.99
93_P104_S0.8240.99
191_R194_E0.8220.99
118_F121_P0.8110.99
319_V325_A0.8080.99
52_T297_L0.8070.99
144_E204_L0.8050.99
266_V342_L0.8050.99
159_L228_F0.8010.99
105_K109_Y0.7970.99
235_E238_E0.7940.98
158_Y266_V0.7940.98
270_M342_L0.7930.98
140_P165_V0.7930.98
110_P115_F0.7890.98
102_L106_A0.7890.98
306_R310_A0.7880.98
94_K100_L0.7860.98
117_K120_K0.7840.98
55_Y253_H0.7840.98
113_Q116_V0.7800.98
93_P99_S0.7780.98
229_A320_T0.7780.98
149_R153_E0.7770.98
182_Y186_K0.7750.98
75_P78_K0.7740.98
102_L105_K0.7740.98
207_N253_H0.7700.98
299_D303_N0.7660.98
35_R39_E0.7650.98
7_L10_M0.7640.98
192_L195_K0.7630.98
119_V123_E0.7630.98
95_L102_L0.7620.98
194_E198_G0.7610.98
122_N126_E0.7610.98
58_L62_A0.7540.98
248_V274_I0.7540.98
97_A107_N0.7540.98
136_I200_K0.7530.98
187_K191_R0.7530.98
33_S37_R0.7520.98
300_M303_N0.7510.98
98_K107_N0.7470.98
184_G188_L0.7470.98
57_R256_R0.7430.98
278_E308_K0.7430.98
110_P120_K0.7370.98
137_I166_K0.7370.98
247_T314_A0.7340.97
334_D340_D0.7340.97
261_S268_E0.7330.97
251_P321_N0.7320.97
32_H49_G0.7310.97
138_L152_V0.7300.97
210_A256_R0.7290.97
30_E36_G0.7280.97
207_N321_N0.7270.97
243_N272_I0.7260.97
95_L100_L0.7240.97
209_A225_A0.7240.97
170_G195_K0.7210.97
54_M301_V0.7200.97
25_V282_F0.7190.97
93_P108_S0.7170.97
29_N32_H0.7170.97
112_V120_K0.7150.97
230_E234_K0.7140.97
206_S251_P0.7080.97
100_L108_S0.7030.97
97_A106_A0.7010.97
13_H67_V0.7000.97
33_S36_G0.6980.97
98_K106_A0.6940.96
136_I159_L0.6910.96
176_H181_N0.6850.96
110_P116_V0.6840.96
187_K190_I0.6810.96
60_E71_Q0.6810.96
24_Y28_R0.6800.96
98_K104_S0.6790.96
95_L107_N0.6780.96
95_L106_A0.6760.96
179_N293_S0.6720.96
236_G239_L0.6710.96
286_A327_A0.6710.96
252_C283_E0.6700.96
219_F222_E0.6680.96
308_K311_K0.6680.96
235_E239_L0.6670.96
192_L212_M0.6660.95
118_F122_N0.6640.95
27_T297_L0.6640.95
233_I266_V0.6620.95
241_K272_I0.6620.95
274_I338_I0.6610.95
113_Q119_V0.6600.95
150_K153_E0.6580.95
328_I331_M0.6510.95
136_I161_K0.6490.95
248_V320_T0.6480.95
74_T182_Y0.6460.95
104_S109_Y0.6450.95
236_G240_P0.6450.95
185_A218_W0.6440.95
36_G47_S0.6430.95
167_I198_G0.6420.95
111_E115_F0.6400.94
12_T65_A0.6390.94
259_L263_I0.6360.94
305_K308_K0.6350.94
253_H322_S0.6350.94
158_Y232_L0.6330.94
318_I338_I0.6330.94
33_S38_I0.6320.94
125_S145_S0.6300.94
129_E132_G0.6300.94
61_T255_Y0.6280.94
85_V89_M0.6280.94
155_A202_I0.6240.94
94_K102_L0.6240.94
34_P42_R0.6230.94
179_N289_D0.6200.93
148_F325_A0.6190.93
74_T177_I0.6180.93
242_V270_M0.6160.93
34_P37_R0.6150.93
171_C175_A0.6140.93
233_I262_H0.6140.93
98_K102_L0.6130.93
290_Y294_H0.6120.93
209_A227_D0.6110.93
139_F192_L0.6110.93
148_F340_D0.6110.93
19_E35_R0.6100.93
114_R118_F0.6090.93
244_D272_I0.6080.93
296_K299_D0.6080.93
95_L99_S0.6070.93
96_L104_S0.6050.93
266_V270_M0.6040.93
36_G39_E0.6040.93
310_A314_A0.6040.93
100_L105_K0.6020.92
148_F326_L0.6020.92
247_T274_I0.6000.92
248_V260_V0.5990.92
238_E269_K0.5990.92
304_V308_K0.5970.92
278_E281_H0.5970.92
152_V156_Y0.5930.92
97_A105_K0.5930.92
93_P105_K0.5920.92
139_F172_C0.5900.92
37_R44_G0.5890.92
11_C17_C0.5870.91
135_D200_K0.5870.91
97_A108_S0.5860.91
19_E62_A0.5860.91
69_Y73_I0.5800.91
183_E186_K0.5770.91
213_K259_L0.5760.91
237_I240_P0.5760.91
248_V267_A0.5740.91
137_I196_V0.5740.91
124_V152_V0.5720.90
9_E39_E0.5710.90
189_A219_F0.5710.90
120_K125_S0.5690.90
96_L106_A0.5680.90
75_P79_S0.5680.90
120_K123_E0.5650.90
251_P320_T0.5640.90
13_H42_R0.5640.90
239_L342_L0.5640.90
117_K126_E0.5640.90
22_P67_V0.5630.90
34_P38_I0.5610.90
203_T225_A0.5600.89
150_K154_K0.5580.89
239_L270_M0.5570.89
113_Q295_P0.5560.89
134_G199_K0.5550.89
139_F212_M0.5530.89
183_E187_K0.5530.89
201_V212_M0.5520.89
94_K99_S0.5480.88
242_V245_T0.5460.88
17_C21_C0.5460.88
174_L211_F0.5450.88
213_K257_Q0.5440.88
93_P100_L0.5430.88
111_E120_K0.5410.88
299_D330_S0.5400.88
122_N125_S0.5390.88
229_A338_I0.5390.88
98_K105_K0.5370.87
212_M215_Y0.5360.87
164_K167_I0.5360.87
98_K101_K0.5350.87
245_T313_E0.5340.87
93_P109_Y0.5320.87
229_A233_I0.5310.87
110_P114_R0.5300.87
11_C14_C0.5300.87
329_R334_D0.5270.86
18_L35_R0.5270.86
138_L163_Y0.5250.86
174_L323_V0.5240.86
235_E240_P0.5230.86
227_D230_E0.5230.86
267_A274_I0.5220.86
95_L103_L0.5220.86
142_C205_Q0.5210.86
291_W323_V0.5210.86
18_L62_A0.5210.86
37_R321_N0.5210.86
22_P54_M0.5200.86
30_E37_R0.5200.86
275_R312_S0.5190.86
248_V264_R0.5190.86
246_F273_K0.5190.86
30_E67_V0.5180.86
14_C17_C0.5130.85
12_T67_V0.5130.85
199_K224_N0.5110.85
227_D231_F0.5110.85
316_K341_L0.5100.85
20_T282_F0.5090.85
155_A232_L0.5070.84
163_Y166_K0.5060.84
250_Y262_H0.5050.84
147_I325_A0.5050.84
23_T321_N0.5040.84
206_S256_R0.5020.84
37_R42_R0.5010.84
247_T275_R0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3kwlA 1 0.8779 100 0.467 Contact Map
3cf4A 2 0.8837 100 0.561 Contact Map
3c8yA 1 0.8605 99.8 0.772 Contact Map
2h88B 1 0.2442 99.5 0.825 Contact Map
2wdqB 1 0.2471 99.4 0.829 Contact Map
1kf6B 1 0.2645 99.4 0.832 Contact Map
4ysxB 1 0.2791 99.4 0.833 Contact Map
2bs2B 1 0.2413 99.2 0.843 Contact Map
4p6vA 1 0.1802 99.1 0.855 Contact Map
1hfeL 2 0.8343 98.6 0.879 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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