GREMLIN Database
Q97U60 - Glycolate oxidase glcD subunit. (GlcD)
UniProt: Q97U60 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 467 (423)
Sequences: 18427 (13778)
Seq/√Len: 669.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
160_K195_R4.0581.00
44_E160_K4.0541.00
55_N435_K3.8681.00
137_I196_A3.6031.00
90_R102_G3.3981.00
157_I199_R3.2671.00
58_N435_K3.1121.00
89_N109_L3.1031.00
100_T197_T3.0741.00
113_T116_N3.0031.00
216_S219_D2.9821.00
100_T195_R2.9811.00
160_K170_E2.9671.00
39_V50_L2.8961.00
334_T337_T2.8101.00
95_D98_E2.7741.00
119_L200_L2.7261.00
161_V183_F2.6661.00
47_V194_L2.6031.00
92_Y102_G2.6021.00
48_I168_V2.5231.00
102_G195_R2.4741.00
163_L167_H2.4621.00
42_G87_R2.4381.00
105_L110_I2.4171.00
158_R170_E2.4021.00
51_V61_Y2.3911.00
158_R197_T2.3801.00
164_S438_L2.3201.00
108_F112_K2.2631.00
96_N117_S2.2251.00
341_F394_K2.1971.00
53_F57_N2.1521.00
91_I105_L2.0951.00
163_L169_E2.0921.00
115_G203_K2.0631.00
44_E168_V2.0521.00
45_E48_I2.0381.00
106_A109_L2.0211.00
40_L87_R2.0001.00
160_K168_V1.9901.00
99_I110_I1.9751.00
158_R172_G1.9751.00
45_E49_S1.9711.00
47_V192_V1.9691.00
161_V191_G1.9641.00
218_D340_R1.9481.00
44_E48_I1.9381.00
88_L102_G1.9041.00
93_S100_T1.9021.00
48_I52_N1.8961.00
44_E194_L1.8961.00
83_I192_V1.8851.00
159_L183_F1.8841.00
114_L200_L1.8711.00
42_G46_E1.8511.00
101_V133_I1.8421.00
64_R67_G1.8251.00
85_L192_V1.8191.00
280_V284_S1.8191.00
63_V192_V1.8011.00
344_E348_K1.7901.00
43_S46_E1.7871.00
49_S52_N1.7841.00
51_V438_L1.7821.00
94_L113_T1.7751.00
138_S186_A1.7581.00
182_I428_L1.7361.00
92_Y195_R1.7171.00
391_L394_K1.7031.00
109_L112_K1.6981.00
99_I198_L1.6851.00
427_R431_T1.6741.00
137_I156_I1.6691.00
383_K387_E1.6491.00
423_T426_R1.6471.00
379_I383_K1.6411.00
390_K394_K1.6401.00
160_K194_L1.6031.00
430_A436_R1.6031.00
54_L81_V1.6021.00
341_F344_E1.5931.00
172_G175_N1.5881.00
390_K415_L1.5831.00
39_V81_V1.5791.00
113_T117_S1.5721.00
183_F191_G1.5701.00
341_F391_L1.5681.00
423_T427_R1.5631.00
52_N55_N1.5611.00
47_V162_L1.5601.00
348_K387_E1.5501.00
138_S193_I1.5321.00
85_L88_L1.5241.00
414_K419_E1.5131.00
137_I198_L1.5111.00
155_S201_F1.5051.00
101_V198_L1.5021.00
171_I176_F1.5001.00
156_I159_L1.4881.00
219_D222_K1.4841.00
136_N152_T1.4781.00
283_V287_R1.4721.00
51_V55_N1.4671.00
218_D222_K1.4641.00
407_I442_K1.4501.00
91_I113_T1.4491.00
162_L194_L1.4481.00
418_S421_D1.4451.00
53_F59_I1.4411.00
307_W311_G1.4371.00
164_S432_F1.4351.00
298_D301_E1.4271.00
343_Y347_K1.4071.00
171_I180_T1.4021.00
426_R430_A1.3991.00
341_F395_V1.3851.00
424_L427_R1.3851.00
102_G105_L1.3791.00
51_V192_V1.3711.00
41_P46_E1.3321.00
429_K436_R1.3321.00
349_Y387_E1.3271.00
47_V83_I1.3141.00
51_V162_L1.3131.00
52_N56_E1.3121.00
276_E280_V1.3121.00
41_P50_L1.3111.00
101_V110_I1.3111.00
222_K226_S1.3091.00
344_E347_K1.3061.00
168_V194_L1.2991.00
99_I114_L1.2841.00
215_N219_D1.2841.00
386_E390_K1.2801.00
131_S136_N1.2791.00
345_I348_K1.2771.00
90_R105_L1.2761.00
162_L168_V1.2691.00
99_I200_L1.2521.00
337_T341_F1.2501.00
122_A155_S1.2391.00
401_G404_G1.2381.00
340_R344_E1.2381.00
287_R290_N1.2381.00
54_L61_Y1.2341.00
377_E380_K1.2291.00
94_L99_I1.2261.00
46_E49_S1.2251.00
40_L84_S1.2231.00
89_N102_G1.2211.00
50_L81_V1.2191.00
422_L426_R1.2151.00
112_K116_N1.2151.00
48_I162_L1.2141.00
242_K246_I1.2021.00
55_N437_L1.1931.00
345_I387_E1.1921.00
284_S288_N1.1821.00
400_S403_H1.1781.00
299_E303_N1.1771.00
169_E176_F1.1761.00
50_L83_I1.1741.00
374_N377_E1.1631.00
246_I249_E1.1601.00
163_L432_F1.1571.00
137_I152_T1.1521.00
380_K383_K1.1481.00
94_L119_L1.1391.00
419_E423_T1.1351.00
61_Y83_I1.1261.00
226_S289_N1.1211.00
314_P317_A1.1161.00
427_R430_A1.1121.00
382_I386_E1.0981.00
272_S276_E1.0811.00
150_G154_D1.0791.00
64_R82_V1.0791.00
282_V286_I1.0771.00
65_G132_S1.0741.00
156_I184_V1.0741.00
405_I408_E1.0701.00
345_I391_L1.0691.00
58_N437_L1.0661.00
183_F193_I1.0651.00
173_S177_F1.0551.00
284_S287_R1.0531.00
226_S229_K1.0451.00
331_P334_T1.0441.00
37_V81_V1.0371.00
134_G196_A1.0341.00
40_L86_T1.0341.00
181_S424_L1.0321.00
111_N125_P1.0301.00
170_E197_T1.0221.00
20_A24_S1.0151.00
61_Y437_L1.0091.00
402_E406_G1.0071.00
47_V88_L1.0061.00
109_L113_T1.0051.00
161_V169_E1.0041.00
285_A289_N1.0041.00
60_K80_E0.9981.00
376_D379_I0.9961.00
133_I198_L0.9951.00
387_E390_K0.9951.00
243_N246_I0.9951.00
383_K386_E0.9931.00
280_V283_V0.9931.00
85_L103_P0.9901.00
235_A238_E0.9891.00
159_L180_T0.9861.00
21_K24_S0.9851.00
300_E304_R0.9841.00
281_R284_S0.9841.00
391_L395_V0.9831.00
327_D331_P0.9821.00
44_E162_L0.9821.00
337_T395_V0.9761.00
178_D181_S0.9711.00
171_I183_F0.9691.00
354_A357_F0.9671.00
36_P79_G0.9651.00
23_Y40_L0.9641.00
44_E102_G0.9631.00
20_A34_E0.9631.00
186_A190_L0.9611.00
271_Y274_N0.9571.00
119_L202_P0.9501.00
65_G85_L0.9411.00
402_E405_I0.9401.00
400_S405_I0.9361.00
64_R84_S0.9341.00
352_P355_N0.9331.00
336_P340_R0.9321.00
306_W309_R0.9201.00
159_L196_A0.9191.00
222_K225_V0.9101.00
155_S199_R0.9061.00
47_V85_L0.9051.00
218_D336_P0.9051.00
133_I196_A0.9031.00
59_I81_V0.9021.00
223_A226_S0.9001.00
286_I291_G0.8991.00
52_N167_H0.8991.00
49_S53_F0.8981.00
170_E195_R0.8961.00
287_R291_G0.8961.00
165_N169_E0.8931.00
108_F128_Y0.8911.00
326_L329_N0.8871.00
89_N105_L0.8871.00
338_M395_V0.8851.00
66_S132_S0.8851.00
305_W310_K0.8811.00
329_N398_V0.8801.00
278_E281_R0.8771.00
225_V229_K0.8761.00
309_R312_A0.8751.00
60_K439_N0.8741.00
378_T382_I0.8691.00
105_L109_L0.8691.00
65_G103_P0.8681.00
182_I190_L0.8641.00
240_L244_S0.8631.00
341_F345_I0.8601.00
266_I269_D0.8551.00
69_S73_A0.8541.00
240_L243_N0.8531.00
108_F129_V0.8521.00
313_F316_F0.8501.00
288_N291_G0.8501.00
299_E302_K0.8491.00
400_S404_G0.8441.00
322_A325_T0.8441.00
301_E304_R0.8401.00
275_V279_E0.8391.00
334_T395_V0.8331.00
107_N136_N0.8321.00
349_Y383_K0.8311.00
393_I415_L0.8311.00
19_E22_L0.8291.00
309_R315_S0.8261.00
414_K422_L0.8251.00
44_E88_L0.8231.00
193_I196_A0.8201.00
86_T132_S0.8191.00
338_M342_T0.8171.00
235_A269_D0.8161.00
17_G20_A0.8151.00
156_I196_A0.8131.00
220_A224_V0.8111.00
246_I250_N0.8101.00
310_K315_S0.8101.00
419_E424_L0.8061.00
122_A201_F0.8051.00
309_R314_P0.8031.00
241_D244_S0.8031.00
99_I113_T0.8011.00
300_E303_N0.8011.00
390_K393_I0.7991.00
254_K257_Y0.7971.00
178_D431_T0.7971.00
345_I349_Y0.7971.00
41_P85_L0.7971.00
21_K34_E0.7961.00
177_F189_T0.7961.00
103_P196_A0.7931.00
157_I197_T0.7931.00
414_K423_T0.7901.00
23_Y38_V0.7901.00
297_K301_E0.7891.00
313_F317_A0.7871.00
303_N307_W0.7861.00
44_E47_V0.7831.00
399_P403_H0.7831.00
214_F223_A0.7811.00
316_F319_Y0.7801.00
389_T393_I0.7801.00
323_Y327_D0.7761.00
312_A315_S0.7751.00
283_V291_G0.7751.00
107_N110_I0.7691.00
353_V357_F0.7681.00
411_K414_K0.7661.00
413_M422_L0.7661.00
277_E280_V0.7621.00
118_N203_K0.7601.00
36_P80_E0.7591.00
375_A378_T0.7591.00
423_T430_A0.7581.00
379_I382_I0.7561.00
274_N277_E0.7551.00
92_Y100_T0.7551.00
285_A288_N0.7551.00
88_L194_L0.7521.00
323_Y326_L0.7521.00
413_M417_Y0.7511.00
63_V85_L0.7511.00
224_V228_Y0.7501.00
172_G176_F0.7501.00
151_T154_D0.7491.00
178_D428_L0.7491.00
311_G314_P0.7491.00
41_P87_R0.7491.00
247_A250_N0.7431.00
310_K314_P0.7431.00
283_V290_N0.7421.00
283_V286_I0.7421.00
337_T340_R0.7421.00
376_D380_K0.7391.00
322_A326_L0.7361.00
248_I251_T0.7361.00
137_I193_I0.7351.00
112_K115_G0.7321.00
399_P402_E0.7291.00
428_L432_F0.7271.00
267_E270_G0.7251.00
273_V276_E0.7241.00
164_S437_L0.7231.00
304_R307_W0.7211.00
314_P318_Y0.7201.00
110_I133_I0.7181.00
51_V164_S0.7171.00
440_P443_L0.7171.00
181_S184_V0.7161.00
400_S406_G0.7151.00
55_N165_N0.7151.00
120_F203_K0.7141.00
346_S349_Y0.7141.00
159_L193_I0.7141.00
173_S176_F0.7121.00
86_T106_A0.7111.00
306_W310_K0.7111.00
38_V82_V0.7051.00
321_P325_T0.7041.00
158_R195_R0.7021.00
249_E252_Q0.7011.00
281_R285_A0.7011.00
325_T328_A0.7001.00
159_L171_I0.6991.00
260_A263_I0.6981.00
429_K439_N0.6971.00
62_I80_E0.6931.00
176_F432_F0.6931.00
210_I214_F0.6921.00
221_G225_V0.6921.00
307_W310_K0.6911.00
234_P240_L0.6911.00
69_S74_T0.6911.00
161_V171_I0.6891.00
305_W308_G0.6861.00
134_G138_S0.6861.00
174_S177_F0.6861.00
436_R439_N0.6851.00
233_T236_A0.6851.00
308_G313_F0.6851.00
315_S318_Y0.6841.00
45_E168_V0.6831.00
53_F81_V0.6831.00
232_V238_E0.6811.00
35_P82_V0.6801.00
310_K313_F0.6791.00
208_K276_E0.6781.00
107_N131_S0.6761.00
305_W309_R0.6761.00
93_S96_N0.6761.00
107_N125_P0.6751.00
242_K261_E0.6721.00
114_L117_S0.6721.00
362_G365_H0.6711.00
46_E50_L0.6681.00
94_L200_L0.6671.00
265_L269_D0.6661.00
403_H406_G0.6651.00
210_I213_S0.6641.00
239_F243_N0.6631.00
48_I51_V0.6631.00
320_S325_T0.6611.00
95_D100_T0.6611.00
385_A389_T0.6601.00
372_P378_T0.6591.00
232_V235_A0.6581.00
91_I101_V0.6581.00
279_E283_V0.6571.00
140_D151_T0.6561.00
41_P47_V0.6561.00
352_P357_F0.6551.00
128_Y131_S0.6531.00
170_E175_N0.6521.00
402_E408_E0.6511.00
302_K306_W0.6501.00
322_A329_N0.6491.00
268_L282_V0.6481.00
320_S324_L0.6481.00
111_N120_F0.6471.00
238_E241_D0.6471.00
160_K197_T0.6451.00
305_W313_F0.6451.00
321_P324_L0.6441.00
234_P238_E0.6431.00
123_P155_S0.6431.00
342_T346_S0.6421.00
41_P88_L0.6421.00
312_A316_F0.6411.00
180_T184_V0.6411.00
285_A291_G0.6381.00
327_D332_R0.6371.00
107_N133_I0.6351.00
238_E242_K0.6341.00
322_A327_D0.6341.00
236_A240_L0.6331.00
311_G316_F0.6321.00
304_R309_R0.6321.00
326_L330_V0.6311.00
24_S32_K0.6301.00
148_K269_D0.6301.00
296_P299_E0.6281.00
169_E172_G0.6271.00
218_D337_T0.6271.00
44_E195_R0.6261.00
313_F319_Y0.6251.00
296_P301_E0.6241.00
388_I392_A0.6241.00
298_D302_K0.6231.00
223_A286_I0.6221.00
264_L267_E0.6211.00
324_L327_D0.6201.00
270_G273_V0.6201.00
227_V282_V0.6181.00
245_I249_E0.6171.00
355_N359_A0.6171.00
238_E244_S0.6161.00
283_V289_N0.6161.00
323_Y328_A0.6141.00
94_L117_S0.6141.00
76_P80_E0.6141.00
221_G224_V0.6141.00
343_Y346_S0.6131.00
234_P241_D0.6131.00
234_P237_M0.6131.00
143_G146_T0.6121.00
126_S136_N0.6111.00
314_P319_Y0.6101.00
407_I410_I0.6101.00
282_V287_R0.6091.00
354_A359_A0.6091.00
239_F244_S0.6091.00
190_L428_L0.6081.00
315_S319_Y0.6071.00
294_F301_E0.6071.00
91_I102_G0.6071.00
172_G177_F0.6061.00
309_R317_A0.6061.00
340_R343_Y0.6061.00
233_T238_E0.6051.00
268_L275_V0.6051.00
413_M416_Y0.6041.00
286_I289_N0.6041.00
164_S435_K0.6031.00
146_T151_T0.6021.00
308_G312_A0.5991.00
375_A379_I0.5981.00
169_E424_L0.5971.00
309_R313_F0.5971.00
60_K440_P0.5961.00
159_L184_V0.5961.00
242_K249_E0.5951.00
417_Y421_D0.5941.00
173_S180_T0.5941.00
330_V338_M0.5941.00
20_A23_Y0.5931.00
269_D272_S0.5921.00
345_I384_A0.5911.00
240_L247_A0.5901.00
62_I76_P0.5891.00
209_T302_K0.5891.00
244_S247_A0.5881.00
306_W313_F0.5881.00
384_A388_I0.5881.00
308_G314_P0.5881.00
302_K305_W0.5881.00
111_N114_L0.5861.00
19_E23_Y0.5851.00
327_D330_V0.5851.00
71_S74_T0.5821.00
224_V227_V0.5791.00
101_V105_L0.5791.00
358_H361_D0.5781.00
412_F415_L0.5771.00
403_H407_I0.5761.00
367_L370_F0.5731.00
66_S106_A0.5731.00
48_I163_L0.5731.00
367_L371_D0.5721.00
247_A251_T0.5711.00
176_F180_T0.5711.00
236_A241_D0.5711.00
243_N250_N0.5701.00
226_S288_N0.5701.00
404_G407_I0.5701.00
98_E333_S0.5701.00
226_S285_A0.5691.00
111_N203_K0.5691.00
301_E306_W0.5671.00
24_S38_V0.5671.00
320_S329_N0.5671.00
179_P432_F0.5651.00
310_K317_A0.5641.00
397_G401_G0.5631.00
239_F242_K0.5621.00
347_K350_G0.5601.00
320_S326_L0.5601.00
236_A239_F0.5591.00
401_G405_I0.5571.00
308_G315_S0.5571.00
108_F130_V0.5551.00
356_S359_A0.5551.00
312_A319_Y0.5541.00
306_W312_A0.5521.00
412_F416_Y0.5511.00
411_K415_L0.5511.00
253_Y256_N0.5501.00
268_L271_Y0.5501.00
311_G317_A0.5491.00
24_S35_P0.5491.00
401_G406_G0.5481.00
401_G407_I0.5471.00
378_T381_A0.5471.00
41_P83_I0.5471.00
325_T367_L0.5461.00
321_P326_L0.5451.00
242_K245_I0.5441.00
25_Y32_K0.5441.00
313_F318_Y0.5441.00
279_E286_I0.5441.00
216_S220_A0.5421.00
311_G315_S0.5411.00
101_V196_A0.5391.00
244_S312_A0.5391.00
106_A132_S0.5381.00
37_V59_I0.5351.00
386_E389_T0.5341.00
352_P356_S0.5341.00
177_F180_T0.5341.00
225_V228_Y0.5331.00
277_E281_R0.5321.00
222_K289_N0.5291.00
173_S184_V0.5291.00
98_E197_T0.5291.00
18_D21_K0.5271.00
270_G274_N0.5260.99
76_P82_V0.5240.99
281_R287_R0.5220.99
189_T443_L0.5220.99
322_A328_A0.5220.99
324_L328_A0.5220.99
42_G88_L0.5220.99
65_G134_G0.5210.99
377_E381_A0.5200.99
400_S408_E0.5200.99
338_M341_F0.5180.99
210_I266_I0.5160.99
387_E391_L0.5150.99
428_L431_T0.5140.99
424_L431_T0.5130.99
292_E295_I0.5130.99
237_M240_L0.5110.99
50_L192_V0.5100.99
25_Y29_I0.5100.99
94_L97_F0.5100.99
171_I175_N0.5080.99
429_K433_D0.5080.99
156_I198_L0.5080.99
422_L425_M0.5070.99
189_T429_K0.5070.99
268_L272_S0.5070.99
322_A331_P0.5070.99
325_T331_P0.5070.99
61_Y81_V0.5060.99
26_P75_T0.5060.99
215_N218_D0.5050.99
33_I78_Q0.5040.99
283_V288_N0.5040.99
241_D246_I0.5030.99
385_A388_I0.5020.99
399_P404_G0.5020.99
70_L367_L0.5010.99
208_K279_E0.5010.99
235_A239_F0.5010.99
307_W314_P0.5000.99
358_H365_H0.5000.99
355_N358_H0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3pm9A 5 0.9486 100 0.28 Contact Map
2uuuA 2 0.8972 100 0.322 Contact Map
1wvfA 2 0.955 100 0.347 Contact Map
4o95A 1 0.8694 100 0.351 Contact Map
1f0xA 1 0.9101 100 0.356 Contact Map
1w1oA 1 0.8908 100 0.357 Contact Map
4xloA 2 0.9251 100 0.357 Contact Map
2exrA 1 0.8994 100 0.36 Contact Map
4mlaA 1 0.8972 100 0.37 Contact Map
4bbyA 2 0.94 100 0.375 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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