GREMLIN Database
Q97U50 - Uncharacterized protein
UniProt: Q97U50 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 131 (116)
Sequences: 13563 (10329)
Seq/√Len: 959.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
18_T22_D2.8571.00
34_S98_H2.6301.00
78_I101_V2.4251.00
16_P68_S2.2871.00
76_I94_N2.2051.00
78_I82_K2.1421.00
15_K18_T2.1391.00
82_K86_E2.0991.00
79_P82_K1.9331.00
80_P109_V1.8541.00
16_P45_I1.8031.00
80_P104_Q1.8001.00
14_V18_T1.7781.00
14_V23_A1.7301.00
14_V35_L1.7021.00
14_V37_I1.6811.00
23_A67_V1.6811.00
66_P69_T1.6331.00
15_K40_E1.6321.00
12_L30_E1.6061.00
79_P104_Q1.6051.00
78_I87_A1.6041.00
76_I96_V1.5491.00
36_I44_P1.5341.00
16_P39_D1.5321.00
97_R114_I1.5191.00
65_S69_T1.4761.00
100_A108_L1.4661.00
23_A48_V1.4571.00
17_E68_S1.4561.00
87_A99_L1.4181.00
26_I30_E1.4071.00
39_D43_K1.3941.00
25_K29_R1.3421.00
90_I94_N1.3171.00
23_A35_L1.3161.00
18_T26_I1.2981.00
48_V53_I1.2901.00
77_T102_V1.2901.00
13_T38_V1.2831.00
78_I99_L1.2811.00
19_S22_D1.2731.00
82_K90_I1.2601.00
14_V67_V1.2491.00
76_I90_I1.2261.00
48_V67_V1.2191.00
39_D45_I1.2151.00
87_A112_I1.2051.00
83_D86_E1.1741.00
6_L84_V1.1681.00
22_D25_K1.1611.00
21_R25_K1.1591.00
21_R64_D1.1511.00
6_L112_I1.1411.00
34_S47_I1.1181.00
44_P108_L1.1141.00
33_G50_E1.0991.00
37_I71_M1.0941.00
12_L26_I1.0891.00
48_V70_I1.0751.00
52_D72_T1.0691.00
20_I70_I1.0651.00
86_E90_I1.0581.00
47_I100_A1.0581.00
50_E54_L1.0511.00
89_I93_Q1.0371.00
65_S70_I1.0251.00
42_N107_E1.0201.00
90_I99_L1.0131.00
24_A53_I1.0081.00
38_V45_I0.9921.00
54_L97_R0.9801.00
46_G71_M0.9791.00
26_I29_R0.9781.00
14_V26_I0.9761.00
84_V117_A0.9751.00
92_Y119_K0.9431.00
44_P100_A0.9421.00
44_P75_L0.9361.00
8_T116_D0.9231.00
36_I100_A0.9231.00
32_L35_L0.9231.00
12_L32_L0.9221.00
67_V71_M0.9031.00
36_I108_L0.8981.00
22_D26_I0.8901.00
78_I90_I0.8801.00
50_E97_R0.8731.00
7_I101_V0.8651.00
55_R58_A0.8651.00
98_H111_V0.8621.00
27_M35_L0.8621.00
17_E66_P0.8181.00
82_K87_A0.8181.00
43_K106_G0.8141.00
62_A65_S0.8081.00
26_I35_L0.8021.00
15_K38_V0.7831.00
23_A27_M0.7831.00
34_S97_R0.7731.00
81_N104_Q0.7711.00
68_S71_M0.7641.00
77_T106_G0.7631.00
61_V65_S0.7621.00
91_M99_L0.7341.00
43_K107_E0.7291.00
13_T42_N0.7291.00
98_H113_S0.7251.00
7_I110_G0.7241.00
86_E89_I0.7091.00
16_P40_E0.7051.00
33_G114_I0.7041.00
97_R115_R0.7021.00
21_R63_L0.6941.00
38_V42_N0.6891.00
102_V106_G0.6781.00
115_R119_K0.6741.00
45_I71_M0.6691.00
102_V108_L0.6641.00
55_R59_D0.6591.00
34_S111_V0.6581.00
33_G97_R0.6511.00
20_I56_A0.6501.00
6_L120_A0.6491.00
85_T89_I0.6481.00
95_N115_R0.6461.00
51_R97_R0.6441.00
34_S49_T0.6391.00
38_V44_P0.6361.00
49_T52_D0.6281.00
54_L58_A0.6271.00
8_T11_P0.6261.00
15_K39_D0.6181.00
28_K59_D0.6121.00
112_I117_A0.6051.00
79_P106_G0.6021.00
79_P102_V0.5971.00
56_A60_E0.5961.00
106_G109_V0.5931.00
114_I118_A0.5931.00
91_M114_I0.5901.00
87_A91_M0.5891.00
88_L118_A0.5841.00
36_I45_I0.5771.00
50_E115_R0.5771.00
19_S66_P0.5751.00
32_L36_I0.5731.00
17_E40_E0.5731.00
84_V88_L0.5631.00
47_I98_H0.5621.00
98_H114_I0.5621.00
72_T75_L0.5591.00
12_L35_L0.5581.00
111_V116_D0.5571.00
33_G36_I0.5531.00
60_E63_L0.5501.00
100_A109_V0.5501.00
88_L117_A0.5481.00
24_A50_E0.5471.00
7_I109_V0.5401.00
50_E98_H0.5311.00
56_A59_D0.5311.00
53_I56_A0.5261.00
90_I93_Q0.5221.00
101_V109_V0.5201.00
96_V99_L0.5181.00
77_T90_I0.5181.00
36_I111_V0.5171.00
56_A70_I0.5111.00
24_A28_K0.5091.00
47_I75_L0.5071.00
47_I72_T0.5021.00
11_P36_I0.5011.00
33_G51_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l2bA 2 0.8779 99.9 0.203 Contact Map
4cooA 2 0.9389 99.9 0.229 Contact Map
3pc3A 2 0.9542 99.8 0.253 Contact Map
1pvmA 2 1 99.8 0.254 Contact Map
2ef7A 3 0.9695 99.8 0.259 Contact Map
4nocA 2 0.9389 99.8 0.262 Contact Map
3fhmA 2 0.9389 99.8 0.262 Contact Map
2qrdG 1 0.9618 99.8 0.265 Contact Map
3t4nC 1 0.9542 99.8 0.265 Contact Map
2j9lA 3 0.9847 99.8 0.267 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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