GAPN - SULSO - GREMLIN Contacts

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GAPN - NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

UniProt:	Q97U30	Sequences: MEKTSVLIKSKELMEIYELKDGVPYFKTYLSGQWISGDEWQDVISPIDLNIIGKIPKLNWNQIDDTLEHIYRKGRWSIRDTPGEKRLDIYKKMASLLDKFKEDFVNVLMINNGKTKSAAEGEVKAAIERLLRADLDVKETRGDYVPGDWSSETLETEAVVRKEPVGVVLSIVPFNYPLFDTVNKIVYTTVIGNAIIIKPPSSTPLPILMLAKVMELASFPKDSFAIITIPGRDMNKVVGDKRIQAISLTGSTETGEEVVRNAGIKQFIMELGGGDPAIVLSDADLAWAAQRIAAGIISYTGQRCDSVKLVLVEEEVYDTLKDLLIKELTKSVKVGDPRDPLTTVGPVIDVKTVDEWEKAIKDAVEKGGKILFGGKRLGPTYIEPVLIEAPKETLKDMYFYNKEVFASAALLIKVKNIDEALEISNSRKYGLDAAIFGKDINKIRKLQRFLEVGAIYINDYPRHGIGYFPFGGRKDSGIGREGIGYTIQYVTAYKSIVYNYKGKGIWEYL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	509 (458)
Sequences:	36260 (21800)
Seq/√Len:	1018.6

ECOLI - PUUC ALDB GABD FEAB BETB ABDH ALDA ASTD SAD EUTE PUTA PAAZ PROA
BACSU - ROCA2 ALDH4 ROCA ALDH1 ALDH5 IOLA ALDY BETB GABD ALDH3 ALDH2 PROA
HALSA - Q9HQZ2 Q9HMJ6 Q9HRB5 Q9HR91
SULSO - GAPN Q97YT9 KGSDH Q97XS9 Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
314_E	415_K	5.364	1.00
314_E	413_K	3.348	1.00
286_A	323_L	3.290	1.00
317_Y	413_K	2.983	1.00
394_L	397_M	2.856	1.00
375_K	383_E	2.850	1.00
281_S	313_E	2.849	1.00
71_Y	242_R	2.827	1.00
42_D	54_K	2.786	1.00
350_V	354_D	2.764	1.00
321_K	411_L	2.664	1.00
361_K	365_E	2.605	1.00
362_D	398_Y	2.571	1.00
98_D	131_L	2.542	1.00
209_M	212_K	2.541	1.00
281_S	315_E	2.497	1.00
100_F	103_D	2.475	1.00
360_I	382_I	2.422	1.00
71_Y	244_Q	2.391	1.00
31_S	72_R	2.318	1.00
437_G	443_I	2.297	1.00
42_D	51_I	2.281	1.00
59_N	62_Q	2.270	1.00
102_E	120_E	2.265	1.00
93_M	214_M	2.194	1.00
215_E	221_K	2.161	1.00
357_E	361_K	2.153	1.00
101_K	124_K	2.141	1.00
347_V	356_W	2.126	1.00
357_E	376_R	2.105	1.00
417_I	442_K	2.070	1.00
163_E	494_K	2.064	1.00
96_L	216_L	2.024	1.00
362_D	366_K	2.023	1.00
239_G	261_N	1.990	1.00
290_Q	328_L	1.983	1.00
325_I	330_K	1.982	1.00
202_S	349_D	1.978	1.00
371_L	388_E	1.963	1.00
428_K	475_D	1.959	1.00
89_I	219_F	1.955	1.00
445_K	449_F	1.927	1.00
277_A	292_I	1.916	1.00
357_E	382_I	1.908	1.00
319_T	323_L	1.897	1.00
364_V	370_I	1.895	1.00
103_D	209_M	1.889	1.00
282_D	442_K	1.880	1.00
417_I	445_K	1.861	1.00
162_K	488_Q	1.861	1.00
387_I	399_F	1.830	1.00
162_K	491_T	1.828	1.00
35_I	65_D	1.820	1.00
68_E	242_R	1.819	1.00
311_L	420_A	1.811	1.00
451_E	474_K	1.806	1.00
311_L	423_I	1.798	1.00
257_E	260_R	1.789	1.00
96_L	217_A	1.789	1.00
256_E	475_D	1.774	1.00
369_K	388_E	1.756	1.00
96_L	99_K	1.733	1.00
313_E	414_V	1.730	1.00
100_F	216_L	1.726	1.00
96_L	213_V	1.724	1.00
75_R	79_R	1.708	1.00
395_K	423_I	1.704	1.00
400_Y	412_I	1.695	1.00
64_D	68_E	1.683	1.00
329_T	386_L	1.679	1.00
325_I	371_L	1.673	1.00
398_Y	402_K	1.667	1.00
211_A	226_I	1.662	1.00
419_E	422_E	1.649	1.00
292_I	320_L	1.646	1.00
107_V	209_M	1.636	1.00
236_K	239_G	1.624	1.00
285_L	323_L	1.621	1.00
310_V	409_A	1.617	1.00
91_K	131_L	1.617	1.00
194_A	223_S	1.616	1.00
322_D	326_K	1.613	1.00
130_L	186_V	1.600	1.00
317_Y	321_K	1.592	1.00
64_D	240_D	1.585	1.00
418_D	449_F	1.572	1.00
95_S	99_K	1.565	1.00
116_K	120_E	1.563	1.00
318_D	413_K	1.562	1.00
370_I	387_I	1.561	1.00
415_K	419_E	1.557	1.00
82_P	85_K	1.556	1.00
297_I	329_T	1.537	1.00
51_I	54_K	1.530	1.00
358_K	398_Y	1.530	1.00
95_S	131_L	1.526	1.00
98_D	127_I	1.521	1.00
317_Y	388_E	1.512	1.00
281_S	442_K	1.505	1.00
350_V	380_T	1.494	1.00
323_L	326_K	1.486	1.00
85_K	88_D	1.477	1.00
91_K	138_K	1.468	1.00
433_A	452_V	1.467	1.00
49_L	378_G	1.462	1.00
289_A	323_L	1.456	1.00
212_K	216_L	1.443	1.00
50_N	378_G	1.437	1.00
280_L	442_K	1.437	1.00
92_K	95_S	1.434	1.00
102_E	106_N	1.425	1.00
319_T	322_D	1.424	1.00
291_R	436_F	1.422	1.00
311_L	414_V	1.418	1.00
62_Q	65_D	1.408	1.00
33_Q	221_K	1.407	1.00
136_D	139_E	1.404	1.00
109_M	119_A	1.398	1.00
361_K	364_V	1.398	1.00
106_N	110_I	1.397	1.00
292_I	310_V	1.394	1.00
101_K	120_E	1.394	1.00
94_A	131_L	1.393	1.00
40_W	54_K	1.384	1.00
130_L	182_V	1.381	1.00
312_V	320_L	1.380	1.00
80_D	449_F	1.376	1.00
359_A	404_V	1.363	1.00
333_K	341_L	1.360	1.00
170_S	195_I	1.351	1.00
280_L	414_V	1.345	1.00
419_E	423_I	1.342	1.00
106_N	338_R	1.331	1.00
416_N	419_E	1.329	1.00
259_V	478_I	1.326	1.00
161_R	448_R	1.319	1.00
44_I	51_I	1.317	1.00
100_F	209_M	1.315	1.00
356_W	406_A	1.315	1.00
211_A	224_F	1.312	1.00
353_V	382_I	1.311	1.00
81_T	85_K	1.310	1.00
326_K	330_K	1.302	1.00
330_K	372_F	1.299	1.00
414_V	423_I	1.298	1.00
45_S	48_D	1.297	1.00
354_D	358_K	1.288	1.00
67_L	240_D	1.286	1.00
353_V	376_R	1.283	1.00
366_K	398_Y	1.280	1.00
421_L	446_L	1.279	1.00
104_F	209_M	1.267	1.00
245_A	268_I	1.265	1.00
353_V	357_E	1.265	1.00
318_D	322_D	1.262	1.00
280_L	446_L	1.261	1.00
214_M	224_F	1.261	1.00
368_G	387_I	1.249	1.00
181_T	197_I	1.249	1.00
321_K	325_I	1.245	1.00
94_A	98_D	1.240	1.00
313_E	416_N	1.239	1.00
39_E	57_K	1.239	1.00
363_A	387_I	1.214	1.00
350_V	353_V	1.208	1.00
67_L	242_R	1.203	1.00
313_E	316_V	1.200	1.00
231_G	235_N	1.200	1.00
278_I	420_A	1.191	1.00
401_N	426_S	1.186	1.00
333_K	343_T	1.175	1.00
162_K	493_Y	1.174	1.00
321_K	371_L	1.171	1.00
396_D	401_N	1.170	1.00
159_V	444_R	1.165	1.00
485_Y	488_Q	1.163	1.00
321_K	388_E	1.163	1.00
93_M	213_V	1.163	1.00
395_K	426_S	1.162	1.00
75_R	194_A	1.159	1.00
335_G	342_T	1.157	1.00
324_L	409_A	1.157	1.00
109_M	337_P	1.156	1.00
332_V	344_V	1.153	1.00
68_E	72_R	1.151	1.00
316_V	319_T	1.150	1.00
81_T	89_I	1.149	1.00
185_I	224_F	1.147	1.00
93_M	219_F	1.146	1.00
201_S	232_R	1.146	1.00
320_L	324_L	1.145	1.00
92_K	96_L	1.141	1.00
433_A	455_I	1.137	1.00
201_S	230_P	1.136	1.00
254_T	257_E	1.135	1.00
401_N	428_K	1.129	1.00
57_K	230_P	1.128	1.00
326_K	331_S	1.125	1.00
484_G	488_Q	1.124	1.00
93_M	130_L	1.119	1.00
447_Q	496_I	1.119	1.00
45_S	336_D	1.112	1.00
418_D	445_K	1.111	1.00
143_D	484_G	1.107	1.00
278_I	446_L	1.105	1.00
106_N	116_K	1.100	1.00
143_D	485_Y	1.099	1.00
358_K	362_D	1.098	1.00
170_S	247_S	1.096	1.00
443_I	457_I	1.095	1.00
169_L	237_V	1.093	1.00
67_L	243_I	1.093	1.00
201_S	231_G	1.091	1.00
257_E	261_N	1.090	1.00
284_D	438_K	1.083	1.00
377_L	383_E	1.076	1.00
421_L	449_F	1.076	1.00
100_F	213_V	1.075	1.00
325_I	372_F	1.070	1.00
256_E	264_I	1.067	1.00
259_V	267_F	1.064	1.00
373_G	385_V	1.061	1.00
57_K	233_D	1.059	1.00
366_K	397_M	1.058	1.00
277_A	307_V	1.057	1.00
47_I	337_P	1.057	1.00
53_G	205_L	1.057	1.00
330_K	383_E	1.056	1.00
91_K	135_L	1.056	1.00
99_K	216_L	1.052	1.00
336_D	339_D	1.052	1.00
222_D	225_A	1.046	1.00
104_F	213_V	1.040	1.00
485_Y	493_Y	1.039	1.00
208_L	228_T	1.038	1.00
417_I	446_L	1.036	1.00
165_V	245_A	1.035	1.00
41_Q	57_K	1.034	1.00
253_E	257_E	1.031	1.00
439_D	442_K	1.030	1.00
353_V	380_T	1.026	1.00
418_D	422_E	1.025	1.00
208_L	226_I	1.024	1.00
49_L	380_T	1.022	1.00
356_W	408_A	1.019	1.00
76_W	80_D	1.017	1.00
230_P	233_D	1.016	1.00
185_I	195_I	1.015	1.00
176_Y	303_R	1.013	1.00
169_L	243_I	1.012	1.00
73_K	194_A	1.011	1.00
278_I	424_S	1.011	1.00
161_R	496_I	1.005	1.00
464_G	467_Y	0.996	1.00
276_P	433_A	0.989	1.00
274_G	308_K	0.986	1.00
259_V	263_G	0.986	1.00
69_H	225_A	0.985	1.00
318_D	321_K	0.982	1.00
33_Q	65_D	0.982	1.00
373_G	383_E	0.976	1.00
414_V	420_A	0.973	1.00
393_T	397_M	0.970	1.00
77_S	81_T	0.966	1.00
31_S	69_H	0.965	1.00
374_G	385_V	0.960	1.00
284_D	287_W	0.959	1.00
286_A	319_T	0.949	1.00
244_Q	451_E	0.949	1.00
480_R	492_A	0.948	1.00
388_E	393_T	0.946	1.00
45_S	110_I	0.944	1.00
359_A	362_D	0.943	1.00
167_V	243_I	0.943	1.00
473_R	492_A	0.940	1.00
434_A	460_Y	0.940	1.00
167_V	194_A	0.935	1.00
165_V	266_Q	0.929	1.00
87_L	138_K	0.927	1.00
163_E	448_R	0.927	1.00
100_F	212_K	0.927	1.00
137_V	190_V	0.927	1.00
105_V	120_E	0.925	1.00
471_G	480_R	0.923	1.00
289_A	324_L	0.923	1.00
422_E	426_S	0.918	1.00
295_G	307_V	0.918	1.00
280_L	417_I	0.917	1.00
126_A	182_V	0.917	1.00
212_K	215_E	0.909	1.00
364_V	387_I	0.909	1.00
45_S	50_N	0.909	1.00
110_I	338_R	0.907	1.00
63_I	169_L	0.907	1.00
363_A	404_V	0.903	1.00
97_L	126_A	0.898	1.00
420_A	423_I	0.896	1.00
368_G	397_M	0.895	1.00
251_S	254_T	0.892	1.00
435_I	446_L	0.891	1.00
79_R	451_E	0.891	1.00
279_V	320_L	0.889	1.00
412_I	423_I	0.888	1.00
103_D	106_N	0.888	1.00
414_V	419_E	0.884	1.00
158_A	468_F	0.884	1.00
91_K	134_D	0.884	1.00
296_I	308_K	0.880	1.00
354_D	357_E	0.880	1.00
356_W	404_V	0.880	1.00
362_D	365_E	0.880	1.00
94_A	134_D	0.878	1.00
287_W	291_R	0.877	1.00
38_D	65_D	0.877	1.00
359_A	398_Y	0.876	1.00
87_L	134_D	0.871	1.00
168_V	245_A	0.869	1.00
288_A	292_I	0.868	1.00
317_Y	411_L	0.868	1.00
395_K	412_I	0.866	1.00
112_N	203_T	0.865	1.00
367_G	397_M	0.864	1.00
165_V	193_N	0.863	1.00
289_A	320_L	0.861	1.00
114_K	122_E	0.861	1.00
285_L	289_A	0.861	1.00
277_A	436_F	0.859	1.00
37_G	62_Q	0.859	1.00
246_I	258_V	0.859	1.00
73_K	223_S	0.857	1.00
230_P	234_M	0.856	1.00
358_K	361_K	0.855	1.00
165_V	492_A	0.852	1.00
83_G	87_L	0.851	1.00
266_Q	492_A	0.850	1.00
219_F	224_F	0.850	1.00
60_W	64_D	0.849	1.00
88_D	92_K	0.848	1.00
289_A	293_A	0.847	1.00
87_L	91_K	0.846	1.00
163_E	473_R	0.845	1.00
72_R	76_W	0.844	1.00
76_W	79_R	0.843	1.00
159_V	498_Y	0.841	1.00
433_A	450_L	0.838	1.00
38_D	59_N	0.838	1.00
44_I	380_T	0.832	1.00
37_G	40_W	0.832	1.00
259_V	262_A	0.829	1.00
280_L	437_G	0.829	1.00
202_S	351_K	0.828	1.00
289_A	328_L	0.826	1.00
197_I	207_I	0.825	1.00
126_A	178_L	0.824	1.00
96_L	100_F	0.822	1.00
421_L	425_N	0.821	1.00
246_I	262_A	0.821	1.00
388_E	413_K	0.817	1.00
61_N	64_D	0.817	1.00
80_D	448_R	0.816	1.00
360_I	408_A	0.813	1.00
65_D	69_H	0.811	1.00
47_I	381_Y	0.810	1.00
259_V	264_I	0.808	1.00
97_L	127_I	0.806	1.00
444_R	448_R	0.805	1.00
288_A	320_L	0.803	1.00
238_V	258_V	0.802	1.00
169_L	246_I	0.798	1.00
181_T	185_I	0.798	1.00
90_Y	190_V	0.795	1.00
41_Q	230_P	0.795	1.00
468_F	495_S	0.795	1.00
293_A	324_L	0.791	1.00
77_S	80_D	0.790	1.00
31_S	221_K	0.786	1.00
256_E	260_R	0.781	1.00
34_W	215_E	0.780	1.00
211_A	215_E	0.777	1.00
61_N	65_D	0.776	1.00
187_Y	486_T	0.775	1.00
69_H	222_D	0.774	1.00
324_L	386_L	0.774	1.00
120_E	340_P	0.772	1.00
92_K	217_A	0.769	1.00
76_W	422_E	0.769	1.00
440_I	443_I	0.767	1.00
78_I	223_S	0.765	1.00
38_D	61_N	0.763	1.00
188_T	195_I	0.763	1.00
191_I	491_T	0.763	1.00
112_N	348_I	0.762	1.00
109_M	116_K	0.761	1.00
353_V	377_L	0.760	1.00
334_V	377_L	0.759	1.00
70_I	225_A	0.758	1.00
238_V	261_N	0.757	1.00
322_D	325_I	0.757	1.00
276_P	424_S	0.755	1.00
356_W	382_I	0.755	1.00
255_G	271_L	0.754	1.00
52_I	110_I	0.754	1.00
58_L	62_Q	0.753	1.00
84_E	138_K	0.753	1.00
255_G	269_M	0.753	1.00
37_G	56_P	0.751	1.00
91_K	95_S	0.749	1.00
105_V	109_M	0.748	1.00
35_I	62_Q	0.746	1.00
260_R	263_G	0.745	1.00
275_D	308_K	0.745	1.00
117_S	343_T	0.743	1.00
208_L	212_K	0.743	1.00
65_D	68_E	0.741	1.00
199_P	228_T	0.740	1.00
452_V	455_I	0.739	1.00
170_S	184_K	0.738	1.00
182_V	210_L	0.738	1.00
60_W	236_K	0.732	1.00
280_L	313_E	0.730	1.00
236_K	257_E	0.729	1.00
313_E	417_I	0.729	1.00
332_V	343_T	0.729	1.00
63_I	67_L	0.728	1.00
105_V	116_K	0.727	1.00
285_L	316_V	0.725	1.00
312_V	316_V	0.724	1.00
416_N	422_E	0.723	1.00
329_T	372_F	0.722	1.00
193_N	491_T	0.717	1.00
350_V	376_R	0.716	1.00
178_L	206_P	0.714	1.00
248_L	254_T	0.714	1.00
359_A	402_K	0.713	1.00
323_L	328_L	0.712	1.00
38_D	62_Q	0.711	1.00
262_A	267_F	0.711	1.00
219_F	223_S	0.710	1.00
60_W	233_D	0.709	1.00
360_I	387_I	0.708	1.00
336_D	342_T	0.707	1.00
104_F	178_L	0.707	1.00
114_K	118_A	0.707	1.00
339_D	342_T	0.706	1.00
440_I	498_Y	0.705	1.00
252_T	475_D	0.704	1.00
325_I	329_T	0.703	1.00
116_K	338_R	0.702	1.00
238_V	246_I	0.701	1.00
417_I	421_L	0.699	1.00
372_F	386_L	0.695	1.00
197_I	224_F	0.693	1.00
351_K	354_D	0.688	1.00
158_A	495_S	0.688	1.00
110_I	205_L	0.687	1.00
229_I	234_M	0.687	1.00
457_I	498_Y	0.685	1.00
58_L	227_I	0.684	1.00
236_K	261_N	0.683	1.00
98_D	124_K	0.683	1.00
282_D	437_G	0.683	1.00
357_E	360_I	0.682	1.00
44_I	49_L	0.681	1.00
108_L	111_N	0.680	1.00
181_T	207_I	0.680	1.00
64_D	242_R	0.680	1.00
196_I	225_A	0.680	1.00
374_G	383_E	0.675	1.00
438_K	441_N	0.674	1.00
107_V	205_L	0.673	1.00
71_Y	76_W	0.672	1.00
364_V	375_K	0.672	1.00
98_D	101_K	0.671	1.00
393_T	399_F	0.670	1.00
58_L	66_T	0.669	1.00
395_K	400_Y	0.668	1.00
310_V	320_L	0.667	1.00
329_T	332_V	0.666	1.00
214_M	219_F	0.665	1.00
89_I	217_A	0.665	1.00
63_I	234_M	0.665	1.00
311_L	395_K	0.662	1.00
393_T	400_Y	0.662	1.00
447_Q	457_I	0.661	1.00
300_T	344_V	0.660	1.00
352_T	355_E	0.658	1.00
109_M	338_R	0.658	1.00
334_V	344_V	0.658	1.00
49_L	350_V	0.657	1.00
324_L	411_L	0.656	1.00
165_V	244_Q	0.656	1.00
70_I	194_A	0.654	1.00
73_K	77_S	0.653	1.00
201_S	355_E	0.652	1.00
83_G	137_V	0.652	1.00
293_A	328_L	0.652	1.00
202_S	348_I	0.648	1.00
31_S	225_A	0.647	1.00
266_Q	489_Y	0.647	1.00
437_G	442_K	0.647	1.00
95_S	98_D	0.646	1.00
56_P	228_T	0.643	1.00
311_L	400_Y	0.642	1.00
349_D	352_T	0.641	1.00
423_I	426_S	0.640	1.00
382_I	385_V	0.640	1.00
78_I	89_I	0.639	1.00
209_M	213_V	0.635	1.00
376_R	383_E	0.635	1.00
79_R	449_F	0.635	1.00
194_A	225_A	0.633	1.00
293_A	332_V	0.632	1.00
55_I	204_P	0.632	1.00
292_I	324_L	0.631	1.00
172_V	181_T	0.630	1.00
325_I	386_L	0.629	1.00
31_S	65_D	0.629	1.00
79_R	164_P	0.629	1.00
45_S	338_R	0.626	1.00
79_R	163_E	0.625	1.00
351_K	355_E	0.625	1.00
334_V	343_T	0.624	1.00
157_E	444_R	0.623	1.00
282_D	438_K	0.621	1.00
68_E	71_Y	0.621	1.00
279_V	288_A	0.621	1.00
94_A	127_I	0.615	1.00
140_T	491_T	0.615	1.00
159_V	496_I	0.615	1.00
387_I	393_T	0.614	1.00
185_I	197_I	0.613	1.00
451_E	473_R	0.612	1.00
32_G	215_E	0.612	1.00
259_V	269_M	0.612	1.00
440_I	444_R	0.612	1.00
285_L	319_T	0.611	1.00
355_E	358_K	0.610	1.00
123_V	127_I	0.610	1.00
140_T	487_I	0.609	1.00
97_L	210_L	0.609	1.00
443_I	447_Q	0.609	1.00
370_I	385_V	0.608	1.00
158_A	497_V	0.607	1.00
89_I	218_S	0.607	1.00
103_D	212_K	0.606	1.00
347_V	352_T	0.605	1.00
404_V	408_A	0.605	1.00
30_L	66_T	0.605	1.00
435_I	443_I	0.602	1.00
268_I	489_Y	0.601	1.00
181_T	210_L	0.600	1.00
96_L	218_S	0.600	1.00
366_K	396_D	0.599	1.00
444_R	498_Y	0.599	1.00
34_W	212_K	0.598	1.00
421_L	445_K	0.598	1.00
178_L	210_L	0.596	1.00
488_Q	491_T	0.595	1.00
114_K	176_Y	0.595	1.00
78_I	189_T	0.593	1.00
40_W	56_P	0.592	1.00
161_R	494_K	0.592	1.00
201_S	257_E	0.591	1.00
314_E	317_Y	0.590	1.00
97_L	178_L	0.588	1.00
184_K	247_S	0.588	1.00
184_K	481_E	0.587	1.00
43_V	111_N	0.586	1.00
455_I	494_K	0.585	1.00
168_V	193_N	0.585	1.00
102_E	116_K	0.585	1.00
89_I	93_M	0.585	1.00
232_R	235_N	0.585	1.00
106_N	109_M	0.584	1.00
108_L	206_P	0.584	1.00
282_D	439_D	0.584	1.00
287_W	290_Q	0.583	1.00
488_Q	493_Y	0.583	1.00
83_G	190_V	0.582	1.00
287_W	438_K	0.581	1.00
43_V	53_G	0.581	1.00
123_V	178_L	0.579	1.00
277_A	310_V	0.577	1.00
441_N	445_K	0.576	1.00
60_W	239_G	0.576	1.00
43_V	204_P	0.576	1.00
283_A	288_A	0.575	1.00
235_N	239_G	0.575	1.00
85_K	89_I	0.575	1.00
108_L	122_E	0.573	1.00
281_S	414_V	0.573	1.00
305_D	464_G	0.573	1.00
312_V	411_L	0.572	1.00
101_K	105_V	0.571	1.00
97_L	104_F	0.569	1.00
245_A	489_Y	0.564	1.00
169_L	196_I	0.564	1.00
421_L	450_L	0.563	1.00
370_I	373_G	0.560	1.00
231_G	234_M	0.560	1.00
170_S	185_I	0.560	1.00
72_R	77_S	0.559	1.00
303_R	306_S	0.559	1.00
230_P	235_N	0.558	1.00
108_L	119_A	0.558	1.00
97_L	130_L	0.557	1.00
66_T	227_I	0.557	1.00
441_N	444_R	0.555	1.00
94_A	130_L	0.554	1.00
347_V	382_I	0.552	1.00
400_Y	423_I	0.552	1.00
333_K	339_D	0.551	1.00
210_L	214_M	0.551	1.00
104_F	123_V	0.549	1.00
93_M	96_L	0.548	1.00
77_S	194_A	0.547	1.00
295_G	460_Y	0.547	1.00
297_I	332_V	0.546	1.00
395_K	422_E	0.545	1.00
69_H	221_K	0.545	1.00
253_E	351_K	0.544	1.00
168_V	195_I	0.543	1.00
71_Y	167_V	0.541	1.00
276_P	452_V	0.540	1.00
135_L	138_K	0.540	1.00
310_V	411_L	0.539	1.00
101_K	127_I	0.539	1.00
454_A	463_H	0.537	1.00
357_E	364_V	0.536	1.00
360_I	385_V	0.535	1.00
70_I	196_I	0.535	1.00
328_L	331_S	0.534	1.00
132_R	136_D	0.533	1.00
277_A	434_A	0.532	1.00
275_D	432_D	0.531	1.00
76_W	449_F	0.531	1.00
122_E	176_Y	0.530	1.00
71_Y	75_R	0.529	1.00
366_K	394_L	0.528	1.00
76_W	81_T	0.528	1.00
105_V	123_V	0.528	1.00
363_A	398_Y	0.528	1.00
450_L	455_I	0.527	1.00
316_V	414_V	0.527	1.00
179_F	183_N	0.526	1.00
133_A	187_Y	0.526	1.00
191_I	487_I	0.526	1.00
196_I	227_I	0.525	1.00
296_I	409_A	0.525	1.00
52_I	205_L	0.524	1.00
252_T	256_E	0.524	1.00
167_V	244_Q	0.523	1.00
92_K	218_S	0.523	1.00
307_V	434_A	0.522	1.00
169_L	238_V	0.522	1.00
70_I	167_V	0.521	1.00
285_L	288_A	0.520	1.00
125_A	179_F	0.520	1.00
424_S	450_L	0.519	1.00
30_L	35_I	0.517	1.00
368_G	393_T	0.516	1.00
451_E	492_A	0.516	1.00
55_I	205_L	0.516	1.00
395_K	401_N	0.515	1.00
359_A	399_F	0.513	1.00
321_K	386_L	0.513	1.00
83_G	141_R	0.511	1.00
399_F	404_V	0.510	1.00
289_A	316_V	0.510	1.00
420_A	424_S	0.508	1.00
39_E	59_N	0.507	1.00
112_N	299_Y	0.507	1.00
201_S	253_E	0.506	1.00
39_E	233_D	0.506	1.00
247_S	490_V	0.506	1.00
66_T	196_I	0.504	1.00
215_E	222_D	0.504	1.00
124_K	127_I	0.503	1.00
267_F	478_I	0.503	1.00
34_W	211_A	0.503	1.00
417_I	449_F	0.503	1.00
232_R	236_K	0.503	1.00
183_N	482_G	0.503	1.00
456_Y	459_D	0.502	1.00
168_V	247_S	0.502	1.00
435_I	457_I	0.501	1.00
215_E	218_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1uxtA	4	0.9725	100	0.064	Contact Map
4yweA	5	0.9116	100	0.07	Contact Map
4pxlA	4	0.9332	100	0.073	Contact Map
3ek1A	5	0.943	100	0.073	Contact Map
4pz2A	4	0.9312	100	0.074	Contact Map
4qf6A	4	0.945	100	0.074	Contact Map
1a4sA	4	0.9627	100	0.075	Contact Map
4o5hA	4	0.9627	100	0.075	Contact Map
4lihA	5	0.943	100	0.076	Contact Map
4wj9A	4	0.945	100	0.077	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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