Q97TZ2 - SULSO - GREMLIN Contacts

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Q97TZ2 - Carbon monoxide dehydrogenase, large chain (CutA-8)

UniProt:	Q97TZ2	Sequences: MYVGKPIKRIEDPKFLTGGSTYVDDIELPGTLFVAFLRSVKPHAKIKIKKNGNNVFTGYDINPGKDFPIPIEETTYVGQPLAIVVGRDRYEAYDLLESIEVEYEELPYVIDPQDALKNDVKVYSKKESNIYEYKKWEGGNIEQSLKEADVVINGELYNQRVIANPLETRGILAYFDGNRLNVWSSTQSAHYLRRNLMNFLGIDNIRVIQPDVGGAFGSKIIAHPEEYAIAKLALKMKRPLKWIPTRSEEMQSAGHGRDKRLKFKVAVKRDGTILGIDGTLIADLGAPYPDANDDEIGNVHSTVRMLLGPYRIQNVRIEEYAVNTNKAPTQSYRGAGRPEATYFIERIINIISLELGKDEFDIREKNLIRELPYKNALGITYDTGDYIGLLNKAREYYETLKKEASTDECIGSSMYVEITAFGPWETARVLAKSDGKIMIITGSGPHGQGDGTAFAQIVADVLEIPIENIEVRWGDTDIISDGIGTWGSRTVTIGGSAMYKAAEELRRRLIEVSAKMLNADVEEVEYKNGIFSHKKSSKSFTIKEVIQNAYSMGYSLDVTYVYNVTKPGYTVPYGVHLALVKVDKETGSIRVRKYIALDDVGRVINPLLAEGQIIGGALQGIGQAIYEGTIYSKEGYLLNSNLTDYGFPTAVEAPRIEWHYIEKGLSGHPTNSKGIGEAGAIASTPAVVNAVEKCIRKKIVNMPIRPEEVI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	710 (694)
Sequences:	5363 (3554)
Seq/√Len:	134.9

ECOLI - XDHD XDHA YAGR
BACSU - XDHD
SULSO - Q97TZ2 Q7LX54 Q97UK2 Q97V74 Q97VI4 Q7LXA2 Q97YU6 Q97UR0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
153_N	264_K	4.232	1.00
37_L	99_I	4.221	1.00
32_L	53_N	3.983	1.00
88_D	91_E	3.893	1.00
364_E	391_N	3.630	1.00
41_K	44_A	3.560	1.00
155_E	262_K	3.554	1.00
398_E	401_K	3.513	1.00
268_K	272_T	3.346	1.00
277_D	316_R	3.330	1.00
267_V	351_I	3.323	1.00
458_V	498_M	3.168	1.00
149_D	268_K	3.095	1.00
149_D	269_R	3.079	1.00
143_Q	147_E	3.068	1.00
437_I	464_I	3.058	1.00
273_I	348_I	3.052	1.00
409_C	413_S	3.043	1.00
357_K	365_K	3.038	1.00
45_K	104_E	2.990	1.00
37_L	96_L	2.934	1.00
140_N	143_Q	2.926	1.00
153_N	262_K	2.848	1.00
279_T	318_E	2.818	1.00
41_K	105_E	2.813	1.00
461_V	503_E	2.802	1.00
44_A	103_Y	2.789	1.00
530_I	539_S	2.786	1.00
53_N	87_R	2.765	1.00
311_R	372_P	2.721	1.00
47_K	102_E	2.709	1.00
361_D	365_K	2.695	1.00
85_V	232_L	2.629	1.00
43_H	106_L	2.614	1.00
264_K	277_D	2.588	1.00
182_V	196_L	2.556	1.00
87_R	91_E	2.483	1.00
499_Y	503_E	2.476	1.00
593_K	657_E	2.467	1.00
688_V	704_I	2.405	1.00
181_N	208_I	2.376	1.00
34_V	242_W	2.337	1.00
272_T	365_K	2.317	1.00
113_Q	260_R	2.296	1.00
174_Y	183_W	2.284	1.00
87_R	238_R	2.277	1.00
581_K	592_R	2.228	1.00
701_N	708_E	2.224	1.00
179_R	477_D	2.218	1.00
357_K	362_I	2.212	1.00
691_V	704_I	2.208	1.00
145_L	266_A	2.178	1.00
397_Y	577_L	2.168	1.00
283_D	326_K	2.161	1.00
66_D	70_P	2.144	1.00
541_T	544_E	2.141	1.00
206_R	475_D	2.141	1.00
279_T	320_Y	2.140	1.00
351_I	362_I	2.138	1.00
67_F	70_P	2.095	1.00
137_E	316_R	2.081	1.00
114_D	117_K	2.068	1.00
265_V	347_I	2.043	1.00
148_A	266_A	2.014	1.00
49_K	100_E	2.000	1.00
617_A	656_I	1.985	1.00
392_K	395_E	1.979	1.00
34_V	83_I	1.976	1.00
393_A	577_L	1.975	1.00
436_K	468_N	1.971	1.00
392_K	659_H	1.965	1.00
36_F	228_A	1.963	1.00
364_E	394_R	1.960	1.00
361_D	364_E	1.953	1.00
40_V	81_L	1.929	1.00
272_T	311_R	1.928	1.00
431_A	505_L	1.921	1.00
506_R	510_I	1.914	1.00
150_V	269_R	1.913	1.00
429_V	439_I	1.904	1.00
157_Y	701_N	1.899	1.00
150_V	267_V	1.896	1.00
618_L	653_A	1.889	1.00
7_I	466_I	1.884	1.00
263_F	347_I	1.883	1.00
391_N	395_E	1.868	1.00
436_K	470_E	1.855	1.00
45_K	72_E	1.851	1.00
578_A	686_A	1.849	1.00
369_R	387_I	1.842	1.00
86_G	92_A	1.835	1.00
24_D	241_K	1.834	1.00
111_D	114_D	1.821	1.00
45_K	73_E	1.805	1.00
409_C	415_Y	1.802	1.00
369_R	372_P	1.801	1.00
455_A	471_V	1.790	1.00
50_K	55_V	1.784	1.00
85_V	236_M	1.783	1.00
520_D	523_E	1.777	1.00
491_V	604_I	1.771	1.00
465_P	468_N	1.759	1.00
396_Y	657_E	1.755	1.00
179_R	204_N	1.745	1.00
413_S	417_E	1.741	1.00
67_F	71_I	1.723	1.00
41_K	103_Y	1.720	1.00
170_G	243_I	1.719	1.00
34_V	240_L	1.712	1.00
360_F	394_R	1.711	1.00
432_K	438_M	1.705	1.00
53_N	238_R	1.693	1.00
83_I	232_L	1.691	1.00
589_I	709_V	1.679	1.00
268_K	274_L	1.673	1.00
432_K	436_K	1.673	1.00
457_I	495_G	1.645	1.00
68_P	71_I	1.643	1.00
54_N	235_K	1.641	1.00
609_A	675_I	1.621	1.00
576_H	594_Y	1.618	1.00
413_S	419_T	1.614	1.00
392_K	396_Y	1.607	1.00
8_K	607_L	1.606	1.00
148_A	274_L	1.601	1.00
705_R	708_E	1.598	1.00
164_N	642_L	1.596	1.00
145_L	264_K	1.595	1.00
265_V	273_I	1.593	1.00
165_P	218_S	1.586	1.00
353_L	692_E	1.585	1.00
602_R	662_E	1.567	1.00
265_V	351_I	1.564	1.00
155_E	260_R	1.546	1.00
262_K	279_T	1.538	1.00
408_E	581_K	1.537	1.00
150_V	354_E	1.536	1.00
437_I	462_L	1.533	1.00
603_V	660_Y	1.526	1.00
427_A	498_M	1.524	1.00
594_Y	617_A	1.522	1.00
439_I	458_V	1.520	1.00
28_L	31_T	1.517	1.00
83_I	228_A	1.517	1.00
578_A	594_Y	1.505	1.00
409_C	419_T	1.499	1.00
609_A	660_Y	1.492	1.00
43_H	73_E	1.491	1.00
142_E	146_K	1.490	1.00
96_L	99_I	1.490	1.00
133_Y	318_E	1.485	1.00
73_E	124_S	1.484	1.00
59_Y	72_E	1.478	1.00
385_D	388_G	1.473	1.00
387_I	391_N	1.469	1.00
142_E	316_R	1.460	1.00
429_V	502_A	1.460	1.00
461_V	670_T	1.458	1.00
181_N	206_R	1.454	1.00
28_L	174_Y	1.451	1.00
151_V	264_K	1.448	1.00
137_E	140_N	1.447	1.00
66_D	69_I	1.440	1.00
396_Y	659_H	1.436	1.00
150_V	268_K	1.433	1.00
23_V	170_G	1.425	1.00
349_N	689_N	1.414	1.00
593_K	655_R	1.414	1.00
364_E	387_I	1.413	1.00
600_V	603_V	1.409	1.00
150_V	355_L	1.408	1.00
620_G	683_S	1.399	1.00
389_L	575_V	1.398	1.00
56_F	236_M	1.392	1.00
353_L	693_K	1.385	1.00
157_Y	260_R	1.383	1.00
393_A	575_V	1.382	1.00
527_K	532_S	1.378	1.00
94_D	98_S	1.375	1.00
65_K	70_P	1.373	1.00
510_I	524_V	1.367	1.00
36_F	242_W	1.366	1.00
591_V	621_I	1.364	1.00
461_V	499_Y	1.362	1.00
410_I	581_K	1.361	1.00
454_F	498_M	1.361	1.00
145_L	275_G	1.360	1.00
91_E	95_L	1.360	1.00
406_T	409_C	1.360	1.00
589_I	691_V	1.358	1.00
150_V	351_I	1.353	1.00
500_K	504_E	1.348	1.00
415_Y	419_T	1.346	1.00
197_M	205_I	1.343	1.00
24_D	243_I	1.335	1.00
459_A	469_I	1.334	1.00
504_E	507_R	1.334	1.00
202_I	205_I	1.327	1.00
180_L	230_A	1.327	1.00
32_L	238_R	1.326	1.00
525_E	532_S	1.322	1.00
273_I	312_I	1.311	1.00
270_D	365_K	1.309	1.00
524_V	531_F	1.296	1.00
31_T	241_K	1.293	1.00
20_S	211_D	1.290	1.00
595_I	657_E	1.288	1.00
457_I	491_V	1.285	1.00
551_S	554_Y	1.284	1.00
154_G	350_I	1.282	1.00
332_Y	619_Q	1.282	1.00
196_L	205_I	1.281	1.00
141_I	145_L	1.281	1.00
144_S	275_G	1.277	1.00
345_E	363_R	1.277	1.00
622_G	648_P	1.276	1.00
178_N	204_N	1.273	1.00
73_E	106_L	1.272	1.00
144_S	314_N	1.269	1.00
417_E	574_G	1.268	1.00
558_V	562_Y	1.266	1.00
56_F	232_L	1.264	1.00
394_R	400_L	1.257	1.00
453_A	491_V	1.256	1.00
173_A	182_V	1.253	1.00
511_E	521_V	1.253	1.00
46_I	101_V	1.246	1.00
258_D	283_D	1.245	1.00
145_L	151_V	1.242	1.00
349_N	359_E	1.240	1.00
232_L	240_L	1.238	1.00
81_L	101_V	1.235	1.00
409_C	417_E	1.235	1.00
396_Y	597_L	1.232	1.00
519_A	533_H	1.225	1.00
397_Y	595_I	1.225	1.00
35_A	96_L	1.221	1.00
261_L	343_F	1.219	1.00
133_Y	320_Y	1.216	1.00
367_L	390_L	1.211	1.00
562_Y	565_T	1.207	1.00
75_T	79_Q	1.205	1.00
267_V	355_L	1.202	1.00
10_I	452_T	1.200	1.00
28_L	172_L	1.199	1.00
142_E	277_D	1.199	1.00
141_I	144_S	1.195	1.00
180_L	202_I	1.192	1.00
355_L	362_I	1.191	0.99
173_A	233_A	1.191	0.99
582_V	589_I	1.191	0.99
513_S	545_V	1.189	0.99
597_L	659_H	1.184	0.99
630_I	639_N	1.184	0.99
559_T	562_Y	1.183	0.99
38_R	248_E	1.183	0.99
532_S	539_S	1.182	0.99
284_L	292_N	1.182	0.99
603_V	609_A	1.182	0.99
516_M	548_N	1.179	0.99
580_V	691_V	1.178	0.99
350_I	700_V	1.174	0.99
254_G	330_Q	1.168	0.99
47_K	100_E	1.164	0.99
164_N	647_F	1.163	0.99
35_A	93_Y	1.163	0.99
14_K	19_G	1.160	0.99
35_A	89_R	1.156	0.99
200_L	230_A	1.155	0.99
393_A	597_L	1.153	0.99
45_K	106_L	1.151	0.99
281_I	320_Y	1.151	0.99
395_E	400_L	1.150	0.99
13_P	17_T	1.148	0.99
303_V	317_I	1.146	0.99
509_L	545_V	1.145	0.99
589_I	625_I	1.144	0.99
504_E	508_R	1.142	0.99
519_A	523_E	1.138	0.99
40_V	103_Y	1.138	0.99
143_Q	146_K	1.137	0.99
468_N	543_K	1.137	0.99
95_L	98_S	1.135	0.99
43_H	325_N	1.130	0.99
27_E	31_T	1.128	0.99
10_I	455_A	1.128	0.99
112_P	281_I	1.128	0.99
496_S	499_Y	1.126	0.99
135_K	318_E	1.124	0.99
578_A	687_V	1.124	0.99
183_W	208_I	1.115	0.99
613_I	617_A	1.110	0.99
299_V	319_E	1.109	0.99
31_T	172_L	1.109	0.99
455_A	466_I	1.105	0.99
154_G	354_E	1.103	0.99
342_Y	688_V	1.103	0.99
147_E	274_L	1.101	0.99
43_H	107_P	1.100	0.99
361_D	400_L	1.095	0.99
407_D	583_D	1.094	0.99
265_V	276_I	1.087	0.99
267_V	362_I	1.087	0.99
510_I	526_Y	1.085	0.99
35_A	92_A	1.083	0.99
123_Y	323_N	1.079	0.99
156_L	347_I	1.077	0.99
173_A	229_I	1.076	0.99
409_C	414_M	1.075	0.99
53_N	91_E	1.074	0.99
81_L	103_Y	1.072	0.99
176_D	181_N	1.071	0.99
456_Q	605_N	1.070	0.99
699_I	704_I	1.068	0.99
267_V	273_I	1.066	0.99
428_R	440_I	1.063	0.99
165_P	249_E	1.062	0.99
52_G	95_L	1.061	0.99
409_C	420_A	1.058	0.99
392_K	597_L	1.053	0.99
215_A	446_H	1.050	0.99
116_L	322_V	1.049	0.99
503_E	507_R	1.048	0.99
117_K	120_V	1.048	0.99
56_F	235_K	1.043	0.99
389_L	597_L	1.038	0.99
388_G	392_K	1.036	0.99
175_F	234_L	1.035	0.99
407_D	584_K	1.035	0.99
578_A	591_V	1.034	0.99
32_L	236_M	1.033	0.99
48_I	101_V	1.033	0.99
413_S	420_A	1.030	0.99
53_N	85_V	1.029	0.99
36_F	83_I	1.028	0.99
74_T	103_Y	1.026	0.98
58_G	71_I	1.025	0.98
507_R	511_E	1.024	0.98
152_I	354_E	1.024	0.98
587_G	709_V	1.024	0.98
61_I	231_K	1.024	0.98
704_I	708_E	1.022	0.98
348_I	362_I	1.022	0.98
625_I	687_V	1.021	0.98
533_H	536_S	1.017	0.98
113_Q	157_Y	1.013	0.98
440_I	472_R	1.009	0.98
526_Y	531_F	1.009	0.98
631_Y	637_L	1.007	0.98
69_I	228_A	1.005	0.98
54_N	236_M	1.004	0.98
599_D	663_K	1.002	0.98
82_A	99_I	1.002	0.98
50_K	99_I	1.001	0.98
55_V	82_A	1.000	0.98
438_M	472_R	0.998	0.98
266_A	275_G	0.998	0.98
51_N	87_R	0.994	0.98
523_E	533_H	0.994	0.98
89_R	93_Y	0.988	0.98
145_L	277_D	0.987	0.98
512_V	549_A	0.984	0.98
152_I	267_V	0.981	0.98
468_N	529_G	0.981	0.98
512_V	545_V	0.978	0.98
48_I	99_I	0.978	0.98
174_Y	181_N	0.977	0.98
452_T	456_Q	0.977	0.98
632_S	636_Y	0.976	0.98
439_I	469_I	0.975	0.98
626_Y	652_E	0.974	0.98
176_D	179_R	0.972	0.98
171_I	229_I	0.972	0.98
113_Q	155_E	0.971	0.98
149_D	274_L	0.970	0.98
281_I	322_V	0.969	0.98
621_I	653_A	0.969	0.98
147_E	268_K	0.969	0.98
402_K	579_L	0.967	0.98
30_G	238_R	0.967	0.98
44_A	106_L	0.967	0.98
141_I	277_D	0.963	0.98
84_V	96_L	0.962	0.98
413_S	421_F	0.962	0.98
141_I	314_N	0.961	0.98
175_F	233_A	0.961	0.98
46_I	81_L	0.960	0.98
66_D	71_I	0.959	0.98
458_V	502_A	0.958	0.98
266_A	274_L	0.958	0.98
152_I	265_V	0.956	0.98
34_V	232_L	0.956	0.98
367_L	387_I	0.956	0.98
163_A	218_S	0.955	0.98
388_G	661_I	0.955	0.98
44_A	101_V	0.953	0.98
185_S	219_K	0.952	0.98
409_C	418_I	0.949	0.97
135_K	316_R	0.946	0.97
557_D	562_Y	0.946	0.97
65_K	68_P	0.944	0.97
259_K	302_T	0.943	0.97
431_A	542_I	0.942	0.97
580_V	591_V	0.941	0.97
144_S	266_A	0.940	0.97
162_I	629_T	0.935	0.97
461_V	506_R	0.934	0.97
56_F	85_V	0.934	0.97
560_Y	565_T	0.928	0.97
141_I	275_G	0.927	0.97
509_L	542_I	0.926	0.97
405_S	409_C	0.925	0.97
461_V	502_A	0.925	0.97
530_I	541_T	0.925	0.97
349_N	363_R	0.924	0.97
406_T	413_S	0.924	0.97
212_V	446_H	0.923	0.97
257_R	339_E	0.920	0.97
399_T	402_K	0.915	0.97
206_R	477_D	0.915	0.97
704_I	709_V	0.911	0.97
174_Y	233_A	0.910	0.97
58_G	72_E	0.909	0.97
82_A	101_V	0.907	0.97
6_P	610_E	0.903	0.97
641_N	644_D	0.901	0.97
175_F	178_N	0.900	0.97
360_F	390_L	0.900	0.97
417_E	421_F	0.899	0.97
187_Q	215_A	0.896	0.96
407_D	413_S	0.896	0.96
109_V	115_A	0.895	0.96
403_E	693_K	0.891	0.96
43_H	108_Y	0.891	0.96
116_L	281_I	0.890	0.96
551_S	556_L	0.889	0.96
229_I	242_W	0.888	0.96
628_G	708_E	0.887	0.96
531_F	545_V	0.883	0.96
118_N	121_K	0.881	0.96
14_K	451_G	0.880	0.96
553_G	556_L	0.880	0.96
92_A	96_L	0.878	0.96
620_G	680_A	0.878	0.96
404_A	407_D	0.877	0.96
59_Y	71_I	0.876	0.96
518_N	533_H	0.873	0.96
37_L	82_A	0.872	0.96
637_L	640_S	0.871	0.96
56_F	231_K	0.870	0.96
310_Y	345_E	0.870	0.96
388_G	391_N	0.868	0.96
220_I	486_W	0.867	0.96
202_I	234_L	0.867	0.96
555_S	558_V	0.865	0.96
247_S	640_S	0.865	0.96
277_D	318_E	0.862	0.96
596_A	617_A	0.862	0.96
443_S	490_T	0.861	0.96
310_Y	363_R	0.857	0.95
610_E	614_I	0.856	0.95
417_E	423_P	0.855	0.95
430_L	440_I	0.853	0.95
507_R	521_V	0.850	0.95
205_I	230_A	0.850	0.95
456_Q	606_P	0.850	0.95
610_E	660_Y	0.850	0.95
46_I	103_Y	0.849	0.95
449_G	608_L	0.849	0.95
151_V	266_A	0.849	0.95
37_L	101_V	0.848	0.95
556_L	562_Y	0.848	0.95
438_M	470_E	0.847	0.95
65_K	69_I	0.845	0.95
458_V	469_I	0.845	0.95
148_A	275_G	0.845	0.95
579_L	593_K	0.845	0.95
33_F	241_K	0.839	0.95
411_G	421_F	0.839	0.95
44_A	74_T	0.837	0.95
558_V	565_T	0.836	0.95
57_T	69_I	0.836	0.95
144_S	274_L	0.834	0.95
48_I	81_L	0.832	0.95
457_I	604_I	0.831	0.95
180_L	234_L	0.830	0.95
264_K	316_R	0.827	0.94
629_T	637_L	0.827	0.94
185_S	212_V	0.826	0.94
554_Y	565_T	0.824	0.94
259_K	282_A	0.822	0.94
112_P	260_R	0.822	0.94
350_I	698_K	0.822	0.94
36_F	80_P	0.821	0.94
93_Y	245_T	0.820	0.94
60_D	235_K	0.819	0.94
448_Q	485_T	0.817	0.94
156_L	350_I	0.812	0.94
14_K	211_D	0.811	0.94
41_K	74_T	0.809	0.94
15_F	22_Y	0.808	0.94
271_G	357_K	0.807	0.94
425_E	494_G	0.807	0.94
156_L	700_V	0.805	0.94
443_S	450_D	0.804	0.94
141_I	316_R	0.803	0.94
600_V	609_A	0.802	0.94
38_R	252_S	0.801	0.93
23_V	26_I	0.799	0.93
52_G	87_R	0.799	0.93
346_R	688_V	0.799	0.93
86_G	95_L	0.797	0.93
342_Y	346_R	0.796	0.93
91_E	94_D	0.796	0.93
558_V	564_V	0.795	0.93
232_L	236_M	0.795	0.93
558_V	561_V	0.793	0.93
263_F	343_F	0.792	0.93
419_T	423_P	0.791	0.93
169_R	249_E	0.791	0.93
267_V	347_I	0.790	0.93
394_R	399_T	0.789	0.93
33_F	89_R	0.786	0.93
110_I	635_G	0.785	0.93
145_L	274_L	0.785	0.93
50_K	57_T	0.784	0.93
692_E	698_K	0.783	0.93
374_K	380_T	0.781	0.93
500_K	503_E	0.779	0.93
140_N	314_N	0.777	0.92
464_I	468_N	0.777	0.92
276_I	312_I	0.777	0.92
7_I	455_A	0.776	0.92
115_A	120_V	0.776	0.92
506_R	526_Y	0.776	0.92
580_V	589_I	0.776	0.92
410_I	413_S	0.775	0.92
561_V	565_T	0.775	0.92
429_V	505_L	0.774	0.92
244_P	249_E	0.774	0.92
307_L	315_V	0.774	0.92
261_L	278_G	0.773	0.92
6_P	607_L	0.773	0.92
557_D	560_Y	0.773	0.92
156_L	346_R	0.772	0.92
89_R	245_T	0.771	0.92
153_N	277_D	0.770	0.92
559_T	565_T	0.769	0.92
600_V	675_I	0.769	0.92
555_S	559_T	0.769	0.92
193_R	476_T	0.769	0.92
347_I	351_I	0.769	0.92
668_H	672_S	0.764	0.92
186_T	192_L	0.763	0.92
453_A	608_L	0.762	0.92
286_A	325_N	0.762	0.92
344_I	347_I	0.762	0.92
79_Q	288_Y	0.761	0.92
576_H	682_A	0.760	0.92
545_V	549_A	0.759	0.92
184_S	192_L	0.757	0.91
168_T	243_I	0.756	0.91
416_V	419_T	0.756	0.91
111_D	260_R	0.755	0.91
138_G	315_V	0.754	0.91
274_L	314_N	0.753	0.91
621_I	687_V	0.752	0.91
518_N	523_E	0.752	0.91
437_I	505_L	0.750	0.91
200_L	231_K	0.750	0.91
178_N	234_L	0.748	0.91
689_N	698_K	0.748	0.91
680_A	684_T	0.747	0.91
28_L	183_W	0.747	0.91
145_L	148_A	0.747	0.91
90_Y	94_D	0.746	0.91
431_A	509_L	0.746	0.91
642_L	647_F	0.746	0.91
653_A	656_I	0.745	0.91
285_G	328_P	0.744	0.91
144_S	148_A	0.744	0.91
42_P	108_Y	0.744	0.91
180_L	205_I	0.743	0.91
554_Y	560_Y	0.741	0.91
594_Y	656_I	0.738	0.90
385_D	661_I	0.734	0.90
632_S	638_L	0.733	0.90
551_S	555_S	0.733	0.90
3_V	460_D	0.732	0.90
510_I	521_V	0.731	0.90
362_I	365_K	0.729	0.90
409_C	412_S	0.727	0.90
302_T	340_A	0.727	0.90
427_A	497_A	0.726	0.90
48_I	55_V	0.726	0.90
192_L	196_L	0.726	0.90
465_P	529_G	0.726	0.90
418_I	422_G	0.726	0.90
190_H	476_T	0.725	0.90
439_I	498_M	0.724	0.90
139_G	144_S	0.724	0.90
357_K	361_D	0.723	0.89
406_T	581_K	0.723	0.89
342_Y	702_M	0.722	0.89
46_I	74_T	0.721	0.89
460_D	602_R	0.721	0.89
532_S	536_S	0.721	0.89
583_D	588_S	0.720	0.89
144_S	147_E	0.720	0.89
153_N	354_E	0.718	0.89
109_V	325_N	0.718	0.89
358_D	399_T	0.718	0.89
559_T	563_N	0.716	0.89
113_Q	281_I	0.716	0.89
594_Y	683_S	0.715	0.89
206_R	476_T	0.712	0.89
175_F	180_L	0.711	0.89
418_I	421_F	0.711	0.89
77_V	636_Y	0.711	0.89
453_A	604_I	0.709	0.89
554_Y	562_Y	0.708	0.88
576_H	683_S	0.706	0.88
266_A	277_D	0.705	0.88
595_I	659_H	0.705	0.88
161_V	623_Q	0.704	0.88
199_F	227_Y	0.703	0.88
599_D	664_G	0.703	0.88
26_I	183_W	0.703	0.88
189_A	476_T	0.703	0.88
692_E	695_I	0.702	0.88
284_L	321_A	0.702	0.88
411_G	415_Y	0.701	0.88
502_A	505_L	0.701	0.88
395_E	398_E	0.700	0.88
350_I	354_E	0.700	0.88
496_S	668_H	0.699	0.88
555_S	560_Y	0.699	0.88
236_M	240_L	0.699	0.88
509_L	531_F	0.698	0.88
42_P	77_V	0.698	0.88
410_I	419_T	0.697	0.88
26_I	210_P	0.696	0.88
580_V	690_A	0.694	0.87
415_Y	420_A	0.694	0.87
347_I	350_I	0.693	0.87
407_D	411_G	0.692	0.87
23_V	243_I	0.692	0.87
429_V	458_V	0.689	0.87
598_D	613_I	0.688	0.87
413_S	416_V	0.687	0.87
110_I	114_D	0.687	0.87
43_H	122_V	0.687	0.87
507_R	510_I	0.687	0.87
34_V	229_I	0.687	0.87
299_V	321_A	0.685	0.87
408_E	411_G	0.684	0.87
429_V	501_A	0.683	0.87
39_S	77_V	0.683	0.87
472_R	478_I	0.683	0.87
21_T	26_I	0.683	0.87
171_I	184_S	0.681	0.86
554_Y	558_V	0.680	0.86
411_G	417_E	0.680	0.86
418_I	423_P	0.680	0.86
391_N	394_R	0.680	0.86
552_M	556_L	0.679	0.86
405_S	581_K	0.678	0.86
458_V	461_V	0.677	0.86
540_F	548_N	0.676	0.86
446_H	485_T	0.676	0.86
414_M	575_V	0.675	0.86
556_L	559_T	0.675	0.86
544_E	547_Q	0.675	0.86
41_K	81_L	0.674	0.86
154_G	700_V	0.674	0.86
140_N	144_S	0.674	0.86
157_Y	258_D	0.673	0.86
582_V	691_V	0.672	0.86
84_V	99_I	0.672	0.86
517_L	540_F	0.672	0.86
273_I	362_I	0.672	0.86
406_T	583_D	0.672	0.86
431_A	437_I	0.670	0.86
136_W	139_G	0.670	0.86
394_R	577_L	0.670	0.86
10_I	466_I	0.670	0.86
353_L	698_K	0.669	0.85
417_E	420_A	0.668	0.85
91_E	98_S	0.668	0.85
614_I	658_W	0.667	0.85
434_D	470_E	0.666	0.85
341_T	685_P	0.665	0.85
551_S	565_T	0.665	0.85
273_I	351_I	0.664	0.85
630_I	638_L	0.662	0.85
149_D	272_T	0.662	0.85
172_L	241_K	0.661	0.85
276_I	347_I	0.660	0.85
389_L	661_I	0.660	0.85
30_G	239_P	0.659	0.85
31_T	239_P	0.659	0.85
27_E	241_K	0.658	0.85
283_D	324_T	0.658	0.85
122_V	325_N	0.658	0.85
74_T	101_V	0.658	0.85
37_L	40_V	0.657	0.84
510_I	531_F	0.656	0.84
398_E	593_K	0.653	0.84
282_A	321_A	0.653	0.84
367_L	384_G	0.652	0.84
508_R	511_E	0.651	0.84
413_S	423_P	0.651	0.84
81_L	99_I	0.648	0.84
137_E	141_I	0.648	0.84
510_I	514_A	0.647	0.84
158_N	342_Y	0.647	0.84
182_V	230_A	0.647	0.84
429_V	437_I	0.647	0.84
419_T	422_G	0.646	0.83
582_V	587_G	0.646	0.83
409_C	421_F	0.645	0.83
116_L	320_Y	0.644	0.83
85_V	240_L	0.644	0.83
116_L	260_R	0.644	0.83
280_L	302_T	0.642	0.83
404_A	411_G	0.642	0.83
268_K	365_K	0.642	0.83
275_G	314_N	0.639	0.83
249_E	253_A	0.639	0.83
626_Y	646_G	0.637	0.83
113_Q	117_K	0.637	0.83
411_G	420_A	0.637	0.83
94_D	97_E	0.637	0.83
75_T	286_A	0.636	0.83
582_V	709_V	0.636	0.83
540_F	545_V	0.635	0.82
292_N	295_E	0.635	0.82
14_K	20_S	0.635	0.82
159_Q	258_D	0.635	0.82
513_S	516_M	0.635	0.82
265_V	362_I	0.634	0.82
516_M	540_F	0.633	0.82
188_S	486_W	0.633	0.82
511_E	515_K	0.633	0.82
292_N	321_A	0.633	0.82
613_I	658_W	0.632	0.82
485_T	490_T	0.632	0.82
169_R	218_S	0.632	0.82
245_T	248_E	0.632	0.82
551_S	558_V	0.630	0.82
356_G	359_E	0.629	0.82
276_I	344_I	0.629	0.82
57_T	60_D	0.629	0.82
111_D	281_I	0.628	0.82
556_L	560_Y	0.628	0.82
156_L	343_F	0.628	0.82
315_V	376_A	0.628	0.82
498_M	502_A	0.627	0.82
463_E	526_Y	0.627	0.82
410_I	417_E	0.626	0.82
697_K	709_V	0.626	0.82
450_D	490_T	0.625	0.81
282_A	299_V	0.624	0.81
454_F	458_V	0.623	0.81
75_T	122_V	0.622	0.81
234_L	237_K	0.622	0.81
107_P	114_D	0.621	0.81
553_G	561_V	0.620	0.81
414_M	419_T	0.619	0.81
193_R	477_D	0.618	0.81
105_E	108_Y	0.617	0.81
9_R	15_F	0.617	0.81
260_R	281_I	0.617	0.81
48_I	57_T	0.616	0.80
52_G	91_E	0.616	0.80
432_K	470_E	0.615	0.80
288_Y	291_A	0.615	0.80
483_I	486_W	0.613	0.80
413_S	418_I	0.613	0.80
346_R	692_E	0.612	0.80
58_G	62_N	0.610	0.80
462_L	502_A	0.610	0.80
341_T	681_I	0.609	0.80
404_A	409_C	0.607	0.80
462_L	469_I	0.607	0.80
443_S	494_G	0.607	0.80
95_L	99_I	0.607	0.80
512_V	516_M	0.606	0.79
610_E	658_W	0.606	0.79
158_N	259_K	0.606	0.79
17_T	20_S	0.606	0.79
346_R	698_K	0.606	0.79
527_K	530_I	0.603	0.79
175_F	179_R	0.603	0.79
21_T	27_E	0.603	0.79
291_A	294_D	0.602	0.79
50_K	59_Y	0.602	0.79
407_D	417_E	0.602	0.79
526_Y	542_I	0.601	0.79
250_M	642_L	0.599	0.79
193_R	197_M	0.598	0.79
47_K	59_Y	0.598	0.79
164_N	629_T	0.598	0.79
326_K	631_Y	0.598	0.79
152_I	351_I	0.597	0.78
35_A	248_E	0.597	0.78
393_A	595_I	0.597	0.78
158_N	623_Q	0.596	0.78
105_E	634_E	0.595	0.78
490_T	494_G	0.595	0.78
512_V	515_K	0.594	0.78
152_I	362_I	0.594	0.78
38_R	80_P	0.594	0.78
407_D	410_I	0.594	0.78
162_I	250_M	0.593	0.78
399_T	577_L	0.592	0.78
577_L	595_I	0.592	0.78
415_Y	423_P	0.592	0.78
75_T	288_Y	0.592	0.78
532_S	537_S	0.592	0.78
278_G	306_L	0.591	0.78
144_S	149_D	0.591	0.78
60_D	63_P	0.590	0.78
409_C	423_P	0.590	0.78
110_I	326_K	0.590	0.78
409_C	584_K	0.588	0.77
416_V	421_F	0.587	0.77
463_E	506_R	0.587	0.77
27_E	172_L	0.587	0.77
263_F	351_I	0.587	0.77
311_R	369_R	0.586	0.77
425_E	482_G	0.585	0.77
278_G	343_F	0.585	0.77
160_R	629_T	0.585	0.77
74_T	77_V	0.585	0.77
542_I	546_I	0.584	0.77
137_E	142_E	0.583	0.77
12_D	15_F	0.582	0.77
55_V	59_Y	0.582	0.77
600_V	660_Y	0.582	0.77
149_D	270_D	0.581	0.77
231_K	236_M	0.580	0.76
613_I	660_Y	0.580	0.76
454_F	494_G	0.579	0.76
514_A	524_V	0.579	0.76
173_A	240_L	0.579	0.76
258_D	329_T	0.578	0.76
491_V	672_S	0.578	0.76
351_I	354_E	0.578	0.76
414_M	420_A	0.577	0.76
15_F	211_D	0.577	0.76
55_V	84_V	0.577	0.76
370_E	387_I	0.576	0.76
556_L	561_V	0.576	0.76
109_V	121_K	0.576	0.76
360_F	412_S	0.575	0.76
402_K	593_K	0.575	0.76
513_S	517_L	0.574	0.76
619_Q	622_G	0.574	0.76
6_P	456_Q	0.574	0.76
274_L	362_I	0.574	0.76
504_E	560_Y	0.573	0.76
26_I	172_L	0.573	0.76
698_K	703_P	0.572	0.75
596_A	613_I	0.571	0.75
404_A	584_K	0.571	0.75
50_K	101_V	0.571	0.75
415_Y	421_F	0.570	0.75
109_V	122_V	0.570	0.75
54_N	85_V	0.570	0.75
312_I	315_V	0.570	0.75
3_V	456_Q	0.569	0.75
417_E	422_G	0.569	0.75
102_E	105_E	0.568	0.75
272_T	313_Q	0.568	0.75
51_N	91_E	0.567	0.75
646_G	649_T	0.565	0.75
47_K	269_R	0.565	0.75
454_F	471_V	0.564	0.74
441_T	454_F	0.562	0.74
425_E	497_A	0.562	0.74
349_N	698_K	0.561	0.74
348_I	355_L	0.561	0.74
171_I	224_P	0.561	0.74
414_M	417_E	0.561	0.74
114_D	119_D	0.561	0.74
28_L	239_P	0.560	0.74
33_F	243_I	0.560	0.74
509_L	549_A	0.559	0.74
407_D	585_E	0.558	0.74
23_V	172_L	0.558	0.74
445_P	451_G	0.558	0.74
144_S	313_Q	0.557	0.73
408_E	413_S	0.556	0.73
154_G	347_I	0.555	0.73
32_L	54_N	0.555	0.73
96_L	100_E	0.554	0.73
409_C	582_V	0.554	0.73
482_G	494_G	0.554	0.73
346_R	689_N	0.553	0.73
368_I	384_G	0.553	0.73
513_S	524_V	0.552	0.73
519_A	524_V	0.552	0.73
150_V	362_I	0.551	0.73
551_S	560_Y	0.551	0.73
342_Y	684_T	0.551	0.73
52_G	86_G	0.550	0.73
454_F	457_I	0.549	0.72
398_E	402_K	0.549	0.72
335_A	487_G	0.549	0.72
84_V	95_L	0.549	0.72
409_C	416_V	0.548	0.72
553_G	564_V	0.548	0.72
274_L	313_Q	0.548	0.72
359_E	689_N	0.548	0.72
456_Q	466_I	0.548	0.72
405_S	408_E	0.547	0.72
12_D	16_L	0.547	0.72
171_I	226_E	0.545	0.72
282_A	302_T	0.545	0.72
549_A	556_L	0.544	0.72
516_M	545_V	0.544	0.72
397_Y	575_V	0.544	0.72
517_L	524_V	0.543	0.72
184_S	226_E	0.542	0.71
425_E	493_I	0.541	0.71
189_A	444_G	0.541	0.71
195_N	222_A	0.541	0.71
161_V	256_G	0.540	0.71
536_S	539_S	0.539	0.71
116_L	120_V	0.538	0.71
514_A	521_V	0.538	0.71
189_A	482_G	0.538	0.71
591_V	594_Y	0.537	0.71
258_D	326_K	0.537	0.71
618_L	621_I	0.537	0.71
457_I	670_T	0.537	0.71
393_A	397_Y	0.536	0.71
86_G	91_E	0.536	0.71
527_K	539_S	0.536	0.71
231_K	235_K	0.535	0.70
533_H	538_K	0.534	0.70
289_P	293_D	0.534	0.70
533_H	537_S	0.533	0.70
183_W	210_P	0.533	0.70
561_V	564_V	0.533	0.70
553_G	558_V	0.533	0.70
48_I	103_Y	0.532	0.70
143_Q	314_N	0.532	0.70
77_V	637_L	0.531	0.70
506_R	531_F	0.531	0.70
111_D	322_V	0.531	0.70
68_P	199_F	0.531	0.70
351_I	357_K	0.531	0.70
408_E	583_D	0.530	0.70
589_I	706_P	0.530	0.70
276_I	306_L	0.529	0.70
695_I	709_V	0.529	0.70
352_S	362_I	0.528	0.70
143_Q	269_R	0.528	0.70
264_K	279_T	0.528	0.70
367_L	386_Y	0.528	0.70
523_E	536_S	0.527	0.69
464_I	469_I	0.527	0.69
551_S	561_V	0.527	0.69
145_L	149_D	0.526	0.69
196_L	227_Y	0.526	0.69
64_G	201_G	0.525	0.69
263_F	348_I	0.525	0.69
450_D	485_T	0.525	0.69
271_G	362_I	0.524	0.69
123_Y	288_Y	0.524	0.69
354_E	698_K	0.524	0.69
603_V	606_P	0.524	0.69
57_T	70_P	0.523	0.69
158_N	261_L	0.523	0.69
582_V	694_C	0.523	0.69
208_I	475_D	0.522	0.69
626_Y	647_F	0.522	0.69
446_H	450_D	0.521	0.68
574_G	598_D	0.521	0.68
33_F	88_D	0.521	0.68
556_L	565_T	0.520	0.68
674_G	679_G	0.520	0.68
492_T	667_G	0.520	0.68
112_P	322_V	0.519	0.68
359_E	363_R	0.519	0.68
524_V	533_H	0.519	0.68
613_I	679_G	0.519	0.68
621_I	626_Y	0.518	0.68
385_D	663_K	0.518	0.68
502_A	506_R	0.518	0.68
161_V	332_Y	0.517	0.68
7_I	452_T	0.517	0.68
185_S	215_A	0.517	0.68
551_S	562_Y	0.516	0.68
456_Q	460_D	0.516	0.68
34_V	85_V	0.516	0.68
451_G	473_W	0.516	0.68
408_E	417_E	0.516	0.68
409_C	422_G	0.515	0.68
39_S	91_E	0.515	0.68
164_N	250_M	0.515	0.68
407_D	415_Y	0.514	0.67
259_K	339_E	0.514	0.67
267_V	354_E	0.513	0.67
46_I	58_G	0.512	0.67
284_L	329_T	0.511	0.67
406_T	584_K	0.511	0.67
169_R	253_A	0.510	0.67
291_A	335_A	0.509	0.67
602_R	664_G	0.509	0.67
208_I	477_D	0.508	0.67
576_H	596_A	0.508	0.67
358_D	362_I	0.507	0.66
40_V	74_T	0.507	0.66
579_L	592_R	0.507	0.66
355_L	365_K	0.506	0.66
175_F	205_I	0.506	0.66
147_E	314_N	0.506	0.66
196_L	201_G	0.505	0.66
412_S	581_K	0.505	0.66
427_A	501_A	0.505	0.66
361_D	394_R	0.505	0.66
420_A	493_I	0.504	0.66
396_Y	595_I	0.504	0.66
412_S	693_K	0.504	0.66
685_P	688_V	0.504	0.66
544_E	548_N	0.503	0.66
359_E	403_E	0.503	0.66
557_D	563_N	0.503	0.66
405_S	410_I	0.502	0.66
554_Y	561_V	0.502	0.66
221_I	290_D	0.502	0.66
463_E	528_N	0.502	0.66
408_E	422_G	0.502	0.66
307_L	312_I	0.501	0.66
272_T	361_D	0.501	0.66
427_A	441_T	0.501	0.66
70_P	74_T	0.500	0.65
505_L	509_L	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1rm6A	2	0.9915	100	0.12	Contact Map
1t3qB	2	0.993	100	0.126	Contact Map
1ffvB	2	0.9887	100	0.134	Contact Map
1n62B	2	0.9915	100	0.137	Contact Map
2w3sB	2	0.9789	100	0.149	Contact Map
3uncA	2	0.9676	100	0.159	Contact Map
3zyvA	3	0.9648	100	0.171	Contact Map
3nvzC	2	0.9676	100	0.172	Contact Map
4usaA	2	0.9521	100	0.175	Contact Map
1dgjA	1	0.9507	100	0.176	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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