GREMLIN Database
Q97TY0 - Glycosyltransferase, putative
UniProt: Q97TY0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 349 (316)
Sequences: 11563 (8920)
Seq/√Len: 501.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_E41_R4.8841.00
23_E102_E4.7581.00
166_K170_M4.4721.00
43_F47_K2.9381.00
88_G163_F2.9251.00
34_V78_A2.9151.00
35_E61_S2.8641.00
168_I195_C2.7961.00
30_E84_G2.7951.00
41_R44_Q2.7651.00
30_E58_R2.7141.00
103_Y202_T2.5981.00
86_I108_F2.5631.00
86_I105_E2.5541.00
2_I34_V2.5001.00
35_E38_S2.3971.00
86_I163_F2.3561.00
13_P48_E2.3491.00
113_V198_V2.3281.00
107_K200_S2.3171.00
171_E193_K2.2991.00
252_P255_M2.2351.00
114_G195_C2.2251.00
99_D103_Y2.1881.00
212_S215_V2.1811.00
13_P17_D2.1111.00
23_E99_D2.1001.00
104_V163_F2.0661.00
44_Q48_E2.0261.00
108_F163_F2.0191.00
185_D189_K1.9671.00
79_L87_I1.9381.00
167_S171_E1.9051.00
24_Y105_E1.8911.00
13_P45_I1.8881.00
168_I190_I1.8861.00
171_E195_C1.8721.00
5_V42_T1.8541.00
88_G101_L1.8481.00
8_E92_G1.8371.00
112_T196_K1.8191.00
17_D49_Y1.8141.00
245_G248_I1.7861.00
33_V46_C1.7491.00
244_D247_L1.7461.00
291_I295_A1.7231.00
103_Y106_P1.7141.00
82_S166_K1.7121.00
18_R96_P1.7121.00
71_K75_L1.6791.00
114_G165_R1.6611.00
128_S131_S1.6351.00
115_A197_I1.6081.00
244_D248_I1.5901.00
41_R45_I1.5841.00
309_F313_N1.5631.00
77_F81_I1.5501.00
30_E83_K1.5301.00
16_L49_Y1.5141.00
23_E98_L1.5131.00
21_N98_L1.5091.00
256_V259_L1.4931.00
7_N38_S1.4881.00
3_V19_L1.4611.00
43_F61_S1.4611.00
319_N322_A1.4511.00
17_D52_K1.4501.00
7_N39_T1.4491.00
18_R95_V1.4401.00
110_D196_K1.4311.00
35_E43_F1.4231.00
242_I245_G1.4161.00
284_S288_L1.4081.00
45_I48_E1.4051.00
46_C59_C1.3931.00
249_V253_F1.3821.00
25_D28_K1.3801.00
280_V284_S1.3761.00
248_I251_T1.3741.00
34_V74_A1.3651.00
219_Q223_W1.3521.00
284_S287_S1.3491.00
96_P100_I1.3491.00
157_I162_S1.3421.00
314_F318_L1.3421.00
77_F80_R1.3391.00
85_E167_S1.3281.00
308_S312_M1.3251.00
141_Y145_I1.3221.00
242_I248_I1.3171.00
59_C62_L1.3091.00
94_T205_S1.3041.00
87_I166_K1.3011.00
251_T255_M1.2931.00
17_D21_N1.2861.00
243_I248_I1.2751.00
306_I309_F1.2701.00
47_K61_S1.2641.00
245_G252_P1.2641.00
115_A190_I1.2591.00
79_L169_I1.2531.00
309_F312_M1.2381.00
24_Y29_Y1.2341.00
249_V255_M1.2331.00
90_F96_P1.2321.00
32_I58_R1.2291.00
100_I161_C1.2281.00
48_E52_K1.2201.00
62_L77_F1.2141.00
134_A137_E1.2091.00
313_N317_A1.1951.00
207_R210_P1.1931.00
75_L89_I1.1911.00
260_V263_S1.1911.00
29_Y101_L1.1891.00
116_V200_S1.1851.00
24_Y28_K1.1751.00
19_L31_I1.1701.00
30_E82_S1.1641.00
6_K68_P1.1601.00
87_I169_I1.1591.00
244_D252_P1.1491.00
86_I165_R1.1431.00
84_G166_K1.1341.00
296_R299_M1.1291.00
247_L251_T1.1261.00
50_E53_Y1.1191.00
120_L160_T1.1131.00
58_R61_S1.1131.00
263_S266_L1.1091.00
251_T254_F1.0971.00
297_R301_E1.0881.00
47_K50_E1.0821.00
78_A82_S1.0801.00
14_R17_D1.0771.00
250_L253_F1.0711.00
249_V252_P1.0551.00
20_V53_Y1.0531.00
137_E140_I1.0471.00
226_G229_E1.0471.00
220_R223_W1.0421.00
5_V12_L1.0391.00
291_I294_I1.0341.00
47_K51_I1.0341.00
60_Y77_F1.0291.00
200_S203_T1.0201.00
48_E51_I1.0111.00
60_Y81_I1.0081.00
143_Y147_G1.0031.00
59_C63_P1.0011.00
43_F46_C0.9961.00
216_L219_Q0.9961.00
15_L19_L0.9931.00
238_I241_R0.9931.00
141_Y144_S0.9901.00
107_K198_V0.9851.00
305_M309_F0.9791.00
275_V278_S0.9781.00
283_A287_S0.9761.00
2_I78_A0.9761.00
49_Y53_Y0.9711.00
287_S295_A0.9691.00
304_Y307_P0.9661.00
308_S311_Y0.9611.00
46_C50_E0.9581.00
5_V92_G0.9521.00
318_L321_T0.9521.00
225_R229_E0.9521.00
76_N80_R0.9511.00
282_L285_L0.9501.00
12_L42_T0.9471.00
127_E131_S0.9471.00
307_P312_M0.9441.00
282_L286_L0.9421.00
9_E45_I0.9391.00
22_L101_L0.9361.00
181_T226_G0.9331.00
145_I148_R0.9291.00
252_P256_V0.9271.00
71_K159_G0.9211.00
219_Q222_R0.9201.00
273_Y276_A0.9181.00
216_L220_R0.9071.00
242_I247_L0.9041.00
277_A284_S0.9031.00
14_R95_V0.8951.00
141_Y146_A0.8941.00
245_G249_V0.8911.00
242_I252_P0.8891.00
262_Y266_L0.8881.00
99_D102_E0.8851.00
281_S284_S0.8851.00
142_E145_I0.8851.00
134_A138_E0.8851.00
49_Y52_K0.8851.00
315_I321_T0.8841.00
248_I252_P0.8821.00
307_P311_Y0.8821.00
36_D70_G0.8821.00
243_I247_L0.8821.00
315_I318_L0.8821.00
167_S170_M0.8801.00
72_S182_E0.8781.00
16_L33_V0.8781.00
122_P209_V0.8751.00
19_L96_P0.8741.00
318_L322_A0.8731.00
97_R206_W0.8721.00
50_E57_I0.8711.00
75_L175_W0.8711.00
296_R300_I0.8681.00
319_N323_I0.8661.00
131_S134_A0.8631.00
288_L291_I0.8601.00
45_I49_Y0.8581.00
88_G100_I0.8541.00
72_S76_N0.8531.00
256_V263_S0.8521.00
287_S290_L0.8501.00
8_E11_V0.8461.00
287_S291_I0.8461.00
281_S285_L0.8461.00
40_D44_Q0.8441.00
108_F165_R0.8431.00
275_V286_L0.8381.00
165_R195_C0.8361.00
15_L20_V0.8331.00
190_I195_C0.8321.00
69_N73_R0.8311.00
124_N131_S0.8291.00
316_V319_N0.8291.00
97_R204_I0.8281.00
246_I252_P0.8271.00
38_S42_T0.8271.00
244_D254_F0.8251.00
79_L82_S0.8251.00
186_I190_I0.8241.00
297_R300_I0.8231.00
44_Q47_K0.8211.00
310_V313_N0.8201.00
250_L254_F0.8161.00
258_N262_Y0.8151.00
12_L33_V0.8141.00
137_E220_R0.8131.00
296_R302_Y0.8121.00
306_I311_Y0.8101.00
104_V108_F0.8071.00
311_Y315_I0.8061.00
5_V33_V0.8031.00
16_L20_V0.8011.00
313_N316_V0.8011.00
172_L190_I0.7831.00
305_M308_S0.7821.00
304_Y309_F0.7811.00
131_S135_A0.7791.00
236_R240_L0.7791.00
58_R81_I0.7781.00
132_R135_A0.7771.00
242_I246_I0.7771.00
279_L283_A0.7761.00
114_G190_I0.7751.00
288_L292_I0.7731.00
312_M315_I0.7711.00
104_V203_T0.7701.00
248_I254_F0.7691.00
304_Y312_M0.7681.00
130_T134_A0.7671.00
13_P49_Y0.7661.00
117_Q120_L0.7641.00
135_A138_E0.7621.00
32_I82_S0.7611.00
12_L16_L0.7601.00
315_I322_A0.7521.00
142_E146_A0.7481.00
305_M312_M0.7461.00
141_Y147_G0.7431.00
107_K116_V0.7421.00
244_D251_T0.7411.00
161_C205_S0.7401.00
298_H301_E0.7401.00
284_S291_I0.7391.00
304_Y308_S0.7371.00
94_T207_R0.7371.00
285_L288_L0.7361.00
108_F113_V0.7351.00
168_I171_E0.7351.00
265_V269_S0.7341.00
60_Y63_P0.7331.00
144_S147_G0.7321.00
243_I246_I0.7311.00
248_I255_M0.7301.00
258_N261_N0.7231.00
296_R301_E0.7191.00
315_I319_N0.7161.00
104_V118_G0.7151.00
114_G168_I0.7151.00
249_V254_F0.7141.00
259_L262_Y0.7131.00
261_N265_V0.7121.00
118_G161_C0.7111.00
278_S285_L0.7091.00
317_A321_T0.7091.00
176_N189_K0.7081.00
246_I249_V0.7071.00
121_V204_I0.7001.00
244_D249_V0.6971.00
281_S288_L0.6971.00
274_I285_L0.6961.00
277_A281_S0.6951.00
250_L255_M0.6951.00
277_A288_L0.6911.00
32_I78_A0.6891.00
306_I310_V0.6881.00
106_P109_E0.6861.00
312_M316_V0.6841.00
42_T46_C0.6841.00
276_A284_S0.6811.00
13_P52_K0.6801.00
117_Q157_I0.6791.00
244_D250_L0.6791.00
305_M311_Y0.6751.00
301_E304_Y0.6751.00
15_L18_R0.6751.00
316_V320_F0.6731.00
165_R168_I0.6731.00
247_L254_F0.6711.00
292_I295_A0.6701.00
298_H302_Y0.6701.00
288_L295_A0.6691.00
315_I323_I0.6681.00
223_W226_G0.6671.00
117_Q122_P0.6641.00
210_P219_Q0.6631.00
133_L136_I0.6631.00
214_R218_R0.6621.00
43_F59_C0.6601.00
275_V279_L0.6591.00
22_L96_P0.6561.00
226_G230_V0.6561.00
278_S288_L0.6551.00
247_L253_F0.6541.00
182_E185_D0.6531.00
50_E54_N0.6461.00
19_L22_L0.6441.00
237_K240_L0.6441.00
22_L102_E0.6441.00
321_T324_F0.6431.00
234_K237_K0.6421.00
46_C49_Y0.6411.00
277_A282_L0.6401.00
242_I253_F0.6401.00
320_F324_F0.6381.00
308_S313_N0.6371.00
176_N179_S0.6361.00
263_S269_S0.6351.00
12_L45_I0.6351.00
136_I139_L0.6341.00
142_E147_G0.6341.00
244_D255_M0.6341.00
224_Y227_H0.6311.00
95_V123_I0.6301.00
3_V15_L0.6271.00
176_N185_D0.6261.00
164_I190_I0.6261.00
71_K182_E0.6261.00
168_I172_L0.6261.00
7_N40_D0.6251.00
280_V283_A0.6241.00
213_L216_L0.6241.00
276_A280_V0.6241.00
115_A122_P0.6231.00
278_S282_L0.6211.00
201_P204_I0.6191.00
268_Y271_S0.6161.00
28_K84_G0.6131.00
105_E163_F0.6121.00
85_E165_R0.6121.00
119_K199_Y0.6111.00
102_E106_P0.6111.00
246_I253_F0.6080.99
76_N79_L0.6060.99
245_G255_M0.6050.99
283_A291_I0.6030.99
304_Y313_N0.6020.99
128_S132_R0.6020.99
274_I277_A0.5980.99
299_M302_Y0.5970.99
63_P67_V0.5960.99
284_S292_I0.5940.99
285_L290_L0.5940.99
320_F323_I0.5930.99
247_L252_P0.5920.99
243_I251_T0.5910.99
22_L29_Y0.5890.99
287_S294_I0.5880.99
17_D20_V0.5860.99
297_R302_Y0.5860.99
312_M319_N0.5850.99
15_L90_F0.5840.99
149_A153_L0.5840.99
217_I221_L0.5810.99
79_L89_I0.5800.99
115_A157_I0.5790.99
4_P74_A0.5780.99
246_I251_T0.5780.99
274_I278_S0.5770.99
311_Y322_A0.5770.99
82_S87_I0.5760.99
19_L90_F0.5740.99
303_F307_P0.5740.99
20_V57_I0.5730.99
245_G251_T0.5720.99
308_S315_I0.5710.99
266_L270_S0.5700.99
80_R170_M0.5700.99
285_L289_L0.5680.99
31_I57_I0.5680.99
7_N42_T0.5670.99
290_L294_I0.5640.99
281_S287_S0.5590.99
107_K110_D0.5570.99
191_V197_I0.5570.99
304_Y311_Y0.5560.99
187_S197_I0.5550.99
16_L31_I0.5550.99
12_L46_C0.5540.99
307_P310_V0.5530.99
256_V260_V0.5510.99
5_V8_E0.5490.99
60_Y78_A0.5480.99
108_F116_V0.5470.99
133_L138_E0.5470.99
37_G62_L0.5450.99
4_P93_D0.5430.99
103_Y200_S0.5430.99
12_L17_D0.5420.99
173_G176_N0.5420.99
175_W178_Y0.5410.99
57_I60_Y0.5410.99
57_I62_L0.5400.99
300_I304_Y0.5400.99
258_N263_S0.5390.99
286_L289_L0.5360.99
275_V282_L0.5350.99
213_L217_I0.5340.99
58_R83_K0.5340.99
257_L261_N0.5320.99
317_A320_F0.5320.99
110_D113_V0.5320.99
303_F308_S0.5300.99
261_N264_L0.5280.99
284_S295_A0.5270.99
157_I187_S0.5270.99
273_Y284_S0.5270.99
223_W227_H0.5260.99
53_Y57_I0.5250.99
313_N319_N0.5240.98
273_Y277_A0.5240.98
4_P75_L0.5240.98
277_A280_V0.5230.98
104_V116_V0.5220.98
237_K241_R0.5220.98
182_E226_G0.5170.98
181_T184_L0.5140.98
6_K37_G0.5120.98
185_D188_L0.5100.98
312_M318_L0.5090.98
258_N264_L0.5080.98
71_K91_D0.5080.98
169_I175_W0.5070.98
115_A120_L0.5050.98
147_G151_V0.5030.98
136_I140_I0.5000.98
248_I253_F0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p02A 1 0.9713 100 0.304 Contact Map
2z86A 2 0.6934 100 0.466 Contact Map
3bcvA 2 0.5014 100 0.487 Contact Map
2d7iA 1 0.9427 100 0.492 Contact Map
1xhbA 1 0.8997 100 0.501 Contact Map
3l7iA 4 0.0287 100 0.504 Contact Map
1qg8A 1 0.6132 100 0.504 Contact Map
5ajoA 1 0.9112 100 0.524 Contact Map
4fixA 3 0.9427 100 0.527 Contact Map
3ckjA 2 0.7106 100 0.538 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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