Q97TX7 - SULSO - GREMLIN Contacts

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Q97TX7 - Glycogen debranching enzyme, hypothetical (TreX-like)

UniProt:	Q97TX7	Sequences: MIPLDQCEEEWLLPTRTGGYASSTICGINARTYHGYLIVPLNQPHHRFLILSKFEDFLLINGDTYSMSTNYYPGSYYPDGYKYLIKVEKNSNSKITWHYDFGYSQVEKTLRVHKGYNAITITYIATRGKFKLCPFITFRSHHLAKKLQNEFFTYEIYPPNTIYILYEGKRILNFEIHDKYELFNSGYWYYNFIYKLDQELGNNYIEDLYNPFCIVSTSNKISVTVYYDQRPKDLSVEENEHYDILKLLSAAGKDFVVKGKDGWAIIAGYHWFDEWGRDTFISLEGLLLVDKQYDIAKEIILKYLNLEKRGMLPNNFISYNGEPVYRGVDISLWAINAIYKTYIYSRDKNFIRKVVDKVLDIIDWYSKGNGVIYNVDNLIFHKGAPRTWMDASYDSRIVTPREGAAVEINALWYNALRVTEFLLNELGEKAEYLSEKAESVKKSFAEKFISQDGLYDYINWDNIPDKSIRPNQIFSISLPFPIIDDKSIASKILTLIESKLLRQYGLSSLSREDPNYKPVYKGDRRSRESLPQWTHMALVTRRLC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	544 (527)
Sequences:	661 (506)
Seq/√Len:	22.0

SULSO - Q97TX7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
476_I	493_L	5.778	1.00
508_S	538_L	5.034	1.00
523_D	526_S	4.316	1.00
499_K	512_E	4.286	1.00
22_S	270_H	3.943	1.00
53_K	70_N	3.888	1.00
331_S	365_Y	3.625	1.00
328_V	408_I	3.560	1.00
56_D	108_K	3.373	1.00
473_I	506_L	3.232	1.00
253_K	292_Q	3.184	1.00
301_L	353_K	3.167	1.00
468_I	495_L	3.102	1.00
365_Y	379_I	3.077	1.00
358_V	419_T	3.072	1.00
424_N	434_S	2.966	0.99
387_T	405_A	2.911	0.99
137_T	208_L	2.820	0.99
502_R	536_M	2.803	0.99
499_K	510_S	2.758	0.99
473_I	476_I	2.708	0.99
474_F	539_V	2.567	0.98
473_I	492_I	2.552	0.98
376_D	404_A	2.516	0.98
272_F	278_D	2.472	0.98
267_A	278_D	2.469	0.98
108_K	123_Y	2.462	0.98
272_F	531_P	2.397	0.97
336_N	340_K	2.365	0.97
473_I	493_L	2.360	0.97
327_G	330_I	2.339	0.97
445_A	488_I	2.303	0.97
396_R	529_S	2.281	0.97
147_L	190_Y	2.253	0.96
339_Y	480_F	2.242	0.96
335_I	358_V	2.216	0.96
35_G	38_I	2.210	0.96
309_R	370_G	2.208	0.96
510_S	513_D	2.204	0.96
11_W	21_A	2.194	0.96
64_T	131_K	2.165	0.95
188_W	207_D	2.129	0.95
310_G	325_Y	2.129	0.95
111_R	120_T	2.126	0.95
275_W	314_N	2.121	0.95
272_F	275_W	2.115	0.95
375_V	379_I	2.077	0.94
406_V	454_L	2.060	0.94
55_E	70_N	2.047	0.94
454_L	492_I	2.040	0.94
467_S	513_D	2.038	0.93
374_N	380_F	2.034	0.93
275_W	390_D	2.007	0.93
274_E	303_Y	1.992	0.93
33_Y	142_H	1.985	0.93
422_L	426_L	1.984	0.93
366_S	436_K	1.983	0.93
442_K	446_E	1.983	0.93
394_D	525_R	1.962	0.92
267_A	272_F	1.951	0.92
449_I	488_I	1.950	0.92
55_E	68_S	1.940	0.92
531_P	537_A	1.927	0.91
25_I	87_V	1.916	0.91
528_E	532_Q	1.905	0.91
366_S	432_Y	1.897	0.91
148_Q	166_Y	1.877	0.90
38_I	49_L	1.870	0.90
315_N	324_V	1.856	0.90
304_L	334_A	1.854	0.90
264_A	274_E	1.831	0.89
71_Y	195_K	1.796	0.88
219_N	222_S	1.770	0.87
362_I	419_T	1.768	0.87
530_L	535_H	1.765	0.87
20_Y	141_H	1.760	0.87
129_K	217_T	1.759	0.87
333_W	411_L	1.751	0.87
182_L	212_F	1.744	0.87
198_Q	204_Y	1.702	0.85
112_V	119_I	1.700	0.85
417_R	437_A	1.695	0.85
10_E	31_R	1.690	0.85
297_K	350_F	1.685	0.85
363_D	367_K	1.680	0.84
532_Q	535_H	1.680	0.84
475_S	478_L	1.675	0.84
134_P	211_P	1.644	0.83
314_N	326_R	1.615	0.82
335_I	365_Y	1.613	0.82
387_T	532_Q	1.611	0.82
156_I	160_N	1.597	0.81
276_G	310_G	1.595	0.81
272_F	390_D	1.591	0.81
24_T	34_H	1.590	0.81
275_W	531_P	1.580	0.80
193_I	198_Q	1.580	0.80
520_Y	532_Q	1.574	0.80
14_P	254_D	1.573	0.80
272_F	528_E	1.571	0.80
11_W	23_S	1.566	0.80
310_G	390_D	1.556	0.79
272_F	281_I	1.555	0.79
72_Y	78_P	1.546	0.79
420_E	437_A	1.544	0.79
307_E	357_K	1.543	0.79
49_L	208_L	1.533	0.78
421_F	480_F	1.527	0.78
292_Q	295_I	1.527	0.78
453_G	491_K	1.520	0.78
189_Y	207_D	1.516	0.78
473_I	496_I	1.515	0.78
414_N	478_L	1.503	0.77
259_G	274_E	1.501	0.77
280_F	303_Y	1.496	0.77
490_S	494_T	1.491	0.76
468_I	499_K	1.490	0.76
139_R	271_W	1.488	0.76
39_V	117_N	1.477	0.76
33_Y	201_G	1.469	0.75
287_L	302_K	1.465	0.75
470_P	540_T	1.462	0.75
411_L	470_P	1.455	0.75
32_T	202_N	1.455	0.75
264_A	303_Y	1.450	0.74
346_R	516_Y	1.443	0.74
56_D	123_Y	1.432	0.73
110_L	119_I	1.415	0.72
275_W	399_T	1.409	0.72
399_T	532_Q	1.408	0.72
196_L	199_E	1.402	0.72
355_V	423_L	1.401	0.72
132_L	222_S	1.398	0.72
450_S	455_Y	1.394	0.71
7_C	71_Y	1.391	0.71
35_G	49_L	1.380	0.70
325_Y	390_D	1.379	0.70
69_T	81_Y	1.379	0.70
60_I	104_S	1.379	0.70
420_E	434_S	1.374	0.70
361_I	367_K	1.371	0.70
16_R	115_G	1.369	0.70
416_L	440_V	1.359	0.69
106_V	125_A	1.355	0.69
278_D	528_E	1.344	0.68
386_R	391_A	1.343	0.68
501_L	539_V	1.342	0.68
341_T	345_S	1.331	0.68
132_L	176_I	1.329	0.68
420_E	433_L	1.328	0.67
17_T	117_N	1.322	0.67
375_V	436_K	1.321	0.67
276_G	327_G	1.320	0.67
37_L	119_I	1.308	0.66
359_L	428_E	1.308	0.66
124_I	223_V	1.307	0.66
142_H	200_L	1.301	0.66
275_W	532_Q	1.295	0.65
107_E	124_I	1.294	0.65
51_L	54_F	1.292	0.65
129_K	215_V	1.291	0.65
339_Y	418_V	1.291	0.65
84_L	504_Y	1.281	0.65
276_G	314_N	1.276	0.64
309_R	364_W	1.270	0.64
314_N	532_Q	1.270	0.64
385_P	397_I	1.266	0.64
101_F	104_S	1.265	0.64
96_T	107_E	1.264	0.64
405_A	408_I	1.254	0.63
44_P	47_R	1.253	0.63
278_D	281_I	1.247	0.62
440_V	443_S	1.243	0.62
454_L	483_I	1.241	0.62
379_I	492_I	1.236	0.62
256_V	265_I	1.222	0.61
369_N	373_Y	1.218	0.61
307_E	311_M	1.216	0.60
121_I	434_S	1.211	0.60
342_Y	425_E	1.211	0.60
284_E	336_N	1.205	0.60
367_K	439_S	1.203	0.60
275_W	278_D	1.198	0.59
484_D	488_I	1.198	0.59
52_S	137_T	1.198	0.59
278_D	390_D	1.194	0.59
351_I	422_L	1.190	0.59
80_G	83_Y	1.188	0.59
372_I	380_F	1.177	0.58
350_F	354_V	1.175	0.58
85_I	100_D	1.175	0.58
29_N	72_Y	1.172	0.58
343_I	421_F	1.172	0.58
394_D	524_R	1.171	0.57
270_H	517_K	1.168	0.57
134_P	194_Y	1.163	0.57
275_W	310_G	1.160	0.57
158_P	424_N	1.159	0.57
524_R	528_E	1.156	0.56
33_Y	197_D	1.154	0.56
89_K	251_A	1.153	0.56
56_D	121_I	1.151	0.56
43_Q	274_E	1.146	0.56
447_K	459_N	1.146	0.56
276_G	330_I	1.142	0.56
263_W	295_I	1.141	0.55
55_E	214_I	1.130	0.55
38_I	141_H	1.128	0.55
57_F	82_K	1.125	0.54
44_P	274_E	1.123	0.54
350_F	353_K	1.121	0.54
325_Y	528_E	1.120	0.54
19_G	117_N	1.120	0.54
414_N	479_P	1.119	0.54
272_F	327_G	1.116	0.54
372_I	375_V	1.115	0.54
331_S	361_I	1.114	0.54
417_R	420_E	1.110	0.53
284_E	340_K	1.110	0.53
457_Y	465_D	1.098	0.53
265_I	286_L	1.097	0.53
58_L	356_D	1.096	0.52
298_E	422_L	1.095	0.52
113_H	116_Y	1.092	0.52
392_S	539_V	1.088	0.52
361_I	365_Y	1.080	0.51
104_S	353_K	1.077	0.51
73_P	77_Y	1.074	0.51
216_S	224_T	1.070	0.51
456_D	469_R	1.070	0.51
520_Y	528_E	1.069	0.51
261_D	492_I	1.069	0.51
275_W	313_P	1.068	0.51
15_T	117_N	1.063	0.50
355_V	409_N	1.063	0.50
495_L	508_S	1.061	0.50
313_P	316_F	1.061	0.50
431_E	435_E	1.058	0.50
272_F	314_N	1.055	0.50
472_Q	483_I	1.051	0.49
278_D	531_P	1.051	0.49
300_I	334_A	1.047	0.49
314_N	399_T	1.046	0.49
333_W	478_L	1.044	0.49
467_S	510_S	1.038	0.49
401_R	456_D	1.037	0.48
200_L	516_Y	1.036	0.48
275_W	325_Y	1.033	0.48
417_R	434_S	1.032	0.48
399_T	520_Y	1.031	0.48
52_S	413_Y	1.030	0.48
35_G	52_S	1.028	0.48
393_Y	397_I	1.025	0.48
44_P	272_F	1.023	0.47
401_R	469_R	1.022	0.47
291_K	358_V	1.021	0.47
275_W	387_T	1.020	0.47
32_T	49_L	1.015	0.47
303_Y	327_G	1.014	0.47
387_T	399_T	1.014	0.47
31_R	502_R	1.014	0.47
133_C	210_N	1.008	0.46
472_Q	496_I	1.008	0.46
157_Y	160_N	0.997	0.46
23_S	29_N	0.997	0.46
272_F	537_A	0.994	0.46
13_L	21_A	0.994	0.46
483_I	489_A	0.990	0.45
288_L	345_S	0.990	0.45
16_R	47_R	0.986	0.45
276_G	325_Y	0.986	0.45
43_Q	259_G	0.981	0.45
314_N	531_P	0.977	0.44
33_Y	271_W	0.976	0.44
517_K	526_S	0.974	0.44
454_L	472_Q	0.972	0.44
41_L	44_P	0.970	0.44
20_Y	38_I	0.970	0.44
49_L	52_S	0.970	0.44
47_R	405_A	0.970	0.44
387_T	528_E	0.968	0.44
386_R	536_M	0.966	0.44
288_L	344_Y	0.964	0.43
387_T	527_R	0.959	0.43
197_D	200_L	0.957	0.43
258_K	263_W	0.956	0.43
503_Q	536_M	0.953	0.43
264_A	273_D	0.951	0.43
413_Y	440_V	0.951	0.43
389_M	532_Q	0.950	0.43
33_Y	200_L	0.948	0.42
140_S	326_R	0.946	0.42
87_V	97_W	0.946	0.42
403_G	527_R	0.945	0.42
267_A	390_D	0.945	0.42
378_L	443_S	0.942	0.42
419_T	433_L	0.939	0.42
360_D	367_K	0.939	0.42
75_S	88_E	0.934	0.42
274_E	314_N	0.929	0.41
267_A	275_W	0.926	0.41
216_S	228_D	0.925	0.41
94_K	109_T	0.924	0.41
132_L	238_E	0.923	0.41
324_V	533_W	0.921	0.41
272_F	276_G	0.919	0.41
60_I	103_Y	0.917	0.40
275_W	327_G	0.916	0.40
417_R	438_E	0.912	0.40
502_R	507_S	0.910	0.40
24_T	67_M	0.908	0.40
108_K	121_I	0.907	0.40
222_S	452_D	0.906	0.40
418_V	422_L	0.905	0.40
144_A	204_Y	0.897	0.39
362_I	508_S	0.896	0.39
56_D	449_I	0.892	0.39
495_L	499_K	0.891	0.39
57_F	64_T	0.890	0.39
285_G	475_S	0.888	0.38
75_S	78_P	0.887	0.38
273_D	318_S	0.887	0.38
52_S	58_L	0.886	0.38
276_G	390_D	0.883	0.38
399_T	527_R	0.879	0.38
399_T	531_P	0.878	0.38
376_D	447_K	0.878	0.38
468_I	512_E	0.877	0.38
451_Q	492_I	0.877	0.38
297_K	347_D	0.876	0.38
95_I	502_R	0.876	0.38
208_L	379_I	0.876	0.38
401_R	412_W	0.875	0.38
212_F	454_L	0.871	0.37
363_D	485_D	0.870	0.37
189_Y	206_E	0.863	0.37
272_F	330_I	0.861	0.37
413_Y	437_A	0.860	0.37
326_R	385_P	0.858	0.37
476_I	508_S	0.853	0.36
100_D	503_Q	0.853	0.36
396_R	525_R	0.851	0.36
476_I	489_A	0.849	0.36
341_T	347_D	0.848	0.36
403_G	469_R	0.847	0.36
29_N	206_E	0.846	0.36
467_S	515_N	0.843	0.36
416_L	465_D	0.841	0.36
403_G	456_D	0.840	0.35
528_E	537_A	0.840	0.35
60_I	63_D	0.837	0.35
520_Y	531_P	0.837	0.35
141_H	273_D	0.831	0.35
78_P	189_Y	0.830	0.35
271_W	470_P	0.829	0.35
506_L	536_M	0.827	0.35
275_W	537_A	0.826	0.35
67_M	87_V	0.825	0.35
29_N	56_D	0.825	0.35
459_N	540_T	0.823	0.34
186_G	208_L	0.818	0.34
202_N	524_R	0.818	0.34
111_R	119_I	0.818	0.34
314_N	390_D	0.817	0.34
457_Y	533_W	0.817	0.34
19_G	47_R	0.816	0.34
401_R	500_L	0.815	0.34
144_A	194_Y	0.814	0.34
326_R	404_A	0.813	0.34
56_D	413_Y	0.811	0.34
441_K	488_I	0.809	0.34
288_L	296_A	0.808	0.33
30_A	34_H	0.806	0.33
48_F	138_F	0.805	0.33
356_D	360_D	0.804	0.33
7_C	28_I	0.803	0.33
186_G	419_T	0.799	0.33
57_F	78_P	0.799	0.33
84_L	110_L	0.797	0.33
447_K	464_P	0.796	0.33
272_F	325_Y	0.795	0.33
481_P	489_A	0.794	0.33
32_T	203_N	0.794	0.33
78_P	207_D	0.794	0.33
253_K	376_D	0.793	0.33
383_G	415_A	0.792	0.33
120_T	501_L	0.790	0.32
23_S	53_K	0.789	0.32
200_L	271_W	0.786	0.32
19_G	257_V	0.786	0.32
87_V	95_I	0.786	0.32
316_F	385_P	0.786	0.32
72_Y	192_F	0.784	0.32
389_M	531_P	0.783	0.32
132_L	485_D	0.781	0.32
23_S	30_A	0.779	0.32
385_P	392_S	0.779	0.32
282_S	362_I	0.779	0.32
400_P	531_P	0.778	0.32
516_Y	539_V	0.777	0.32
411_L	478_L	0.776	0.32
336_N	339_Y	0.775	0.32
160_N	214_I	0.775	0.32
308_K	311_M	0.772	0.31
482_I	489_A	0.770	0.31
112_V	234_L	0.766	0.31
346_R	490_S	0.765	0.31
264_A	323_P	0.761	0.31
259_G	266_I	0.755	0.30
500_L	509_L	0.754	0.30
197_D	202_N	0.754	0.30
272_F	387_T	0.754	0.30
139_R	211_P	0.752	0.30
12_L	110_L	0.750	0.30
51_L	172_L	0.750	0.30
272_F	532_Q	0.750	0.30
497_E	501_L	0.750	0.30
22_S	536_M	0.747	0.30
389_M	537_A	0.745	0.30
300_I	310_G	0.745	0.30
334_A	449_I	0.745	0.30
468_I	513_D	0.744	0.30
266_I	269_Y	0.744	0.30
106_V	423_L	0.744	0.30
392_S	404_A	0.744	0.30
258_K	261_D	0.740	0.29
263_W	298_E	0.740	0.29
392_S	396_R	0.740	0.29
387_T	401_R	0.739	0.29
272_F	535_H	0.738	0.29
413_Y	417_R	0.737	0.29
327_G	390_D	0.737	0.29
70_N	78_P	0.736	0.29
60_I	102_G	0.735	0.29
360_D	364_W	0.735	0.29
236_V	349_N	0.735	0.29
244_I	422_L	0.733	0.29
407_E	471_N	0.732	0.29
166_Y	169_K	0.731	0.29
105_Q	126_T	0.731	0.29
82_K	101_F	0.731	0.29
414_N	480_F	0.731	0.29
346_R	488_I	0.730	0.29
365_Y	375_V	0.729	0.29
389_M	401_R	0.728	0.29
393_Y	533_W	0.726	0.29
275_W	326_R	0.726	0.29
274_E	385_P	0.725	0.29
435_E	439_S	0.724	0.29
476_I	481_P	0.722	0.28
175_E	468_I	0.722	0.28
359_L	363_D	0.722	0.28
33_Y	140_S	0.721	0.28
78_P	188_W	0.720	0.28
343_I	510_S	0.716	0.28
437_A	440_V	0.716	0.28
159_P	192_F	0.715	0.28
190_Y	206_E	0.714	0.28
335_I	449_I	0.714	0.28
327_G	365_Y	0.713	0.28
528_E	531_P	0.712	0.28
314_N	327_G	0.710	0.28
29_N	53_K	0.710	0.28
297_K	393_Y	0.710	0.28
387_T	403_G	0.708	0.28
42_N	466_K	0.707	0.28
166_Y	170_R	0.706	0.28
134_P	454_L	0.706	0.28
15_T	112_V	0.704	0.28
473_I	479_P	0.704	0.28
275_W	279_T	0.703	0.27
63_D	102_G	0.703	0.27
365_Y	408_I	0.702	0.27
154_Y	161_T	0.700	0.27
200_L	212_F	0.700	0.27
139_R	212_F	0.700	0.27
318_S	333_W	0.699	0.27
33_Y	387_T	0.698	0.27
342_Y	346_R	0.698	0.27
388_W	471_N	0.698	0.27
402_E	405_A	0.697	0.27
16_R	44_P	0.697	0.27
444_F	482_I	0.697	0.27
406_V	410_A	0.696	0.27
421_F	477_S	0.694	0.27
253_K	404_A	0.694	0.27
453_G	468_I	0.694	0.27
274_E	316_F	0.693	0.27
428_E	438_E	0.693	0.27
25_I	155_E	0.691	0.27
237_E	362_I	0.691	0.27
30_A	76_Y	0.691	0.27
311_M	402_E	0.690	0.27
275_W	528_E	0.687	0.27
228_D	233_D	0.686	0.27
181_E	352_R	0.686	0.27
276_G	313_P	0.685	0.26
334_A	358_V	0.685	0.26
465_D	493_L	0.684	0.26
114_K	497_E	0.684	0.26
315_N	318_S	0.683	0.26
285_G	401_R	0.683	0.26
29_N	70_N	0.682	0.26
304_L	354_V	0.682	0.26
349_N	434_S	0.682	0.26
351_I	354_V	0.682	0.26
10_E	23_S	0.681	0.26
294_D	298_E	0.681	0.26
285_G	469_R	0.679	0.26
19_G	112_V	0.678	0.26
165_L	169_K	0.677	0.26
483_I	492_I	0.675	0.26
99_Y	409_N	0.675	0.26
373_Y	386_R	0.675	0.26
179_K	182_L	0.675	0.26
377_N	383_G	0.674	0.26
293_Y	297_K	0.674	0.26
299_I	476_I	0.674	0.26
17_T	39_V	0.674	0.26
292_Q	342_Y	0.672	0.26
371_V	374_N	0.670	0.26
269_Y	285_G	0.668	0.26
364_W	379_I	0.667	0.26
314_N	330_I	0.666	0.25
391_A	399_T	0.666	0.25
31_R	34_H	0.666	0.25
403_G	412_W	0.665	0.25
139_R	516_Y	0.665	0.25
267_A	314_N	0.663	0.25
401_R	534_T	0.663	0.25
366_S	375_V	0.662	0.25
504_Y	529_S	0.658	0.25
469_R	531_P	0.657	0.25
49_L	72_Y	0.657	0.25
143_L	270_H	0.657	0.25
275_W	405_A	0.656	0.25
391_A	523_D	0.656	0.25
109_T	124_I	0.656	0.25
133_C	213_C	0.655	0.25
265_I	298_E	0.654	0.25
402_E	474_F	0.654	0.25
142_H	259_G	0.652	0.25
335_I	415_A	0.651	0.25
336_N	409_N	0.649	0.25
414_N	483_I	0.649	0.25
290_D	533_W	0.649	0.25
405_A	457_Y	0.649	0.25
73_P	193_I	0.649	0.25
410_A	508_S	0.648	0.25
283_L	393_Y	0.647	0.25
348_K	426_L	0.642	0.24
25_I	74_G	0.642	0.24
201_G	269_Y	0.641	0.24
44_P	259_G	0.640	0.24
311_M	370_G	0.640	0.24
351_I	426_L	0.639	0.24
19_G	323_P	0.638	0.24
340_K	344_Y	0.638	0.24
408_I	482_I	0.637	0.24
197_D	201_G	0.636	0.24
79_D	82_K	0.635	0.24
137_T	206_E	0.635	0.24
252_G	516_Y	0.634	0.24
275_W	389_M	0.634	0.24
197_D	249_S	0.632	0.24
51_L	79_D	0.631	0.24
142_H	207_D	0.631	0.24
257_V	263_W	0.630	0.24
417_R	441_K	0.630	0.24
38_I	419_T	0.628	0.24
281_I	314_N	0.627	0.24
352_R	428_E	0.625	0.23
163_Y	209_Y	0.624	0.23
101_F	307_E	0.623	0.23
331_S	347_D	0.622	0.23
200_L	207_D	0.621	0.23
45_H	66_S	0.621	0.23
44_P	316_F	0.620	0.23
23_S	73_P	0.619	0.23
128_G	251_A	0.619	0.23
41_L	48_F	0.618	0.23
283_L	287_L	0.617	0.23
72_Y	459_N	0.616	0.23
12_L	18_G	0.614	0.23
86_K	98_H	0.613	0.23
362_I	440_V	0.613	0.23
8_E	473_I	0.613	0.23
314_N	537_A	0.612	0.23
311_M	449_I	0.610	0.23
280_F	316_F	0.609	0.23
421_F	425_E	0.608	0.23
182_L	209_Y	0.608	0.23
387_T	537_A	0.607	0.23
308_K	370_G	0.606	0.23
261_D	265_I	0.606	0.23
67_M	79_D	0.604	0.22
123_Y	413_Y	0.603	0.22
255_F	477_S	0.602	0.22
412_W	469_R	0.601	0.22
259_G	323_P	0.601	0.22
139_R	470_P	0.601	0.22
23_S	270_H	0.601	0.22
419_T	423_L	0.600	0.22
310_G	327_G	0.599	0.22
59_L	64_T	0.596	0.22
201_G	531_P	0.595	0.22
51_L	119_I	0.594	0.22
293_Y	350_F	0.594	0.22
16_R	43_Q	0.594	0.22
199_E	521_K	0.593	0.22
311_M	327_G	0.593	0.22
399_T	405_A	0.592	0.22
389_M	469_R	0.592	0.22
423_L	530_L	0.592	0.22
44_P	533_W	0.591	0.22
430_A	437_A	0.590	0.22
274_E	313_P	0.589	0.22
55_E	73_P	0.588	0.22
266_I	314_N	0.588	0.22
339_Y	422_L	0.587	0.22
469_R	534_T	0.585	0.22
438_E	530_L	0.584	0.21
412_W	456_D	0.584	0.21
208_L	212_F	0.584	0.21
121_I	513_D	0.583	0.21
61_N	83_Y	0.583	0.21
127_R	503_Q	0.581	0.21
193_I	204_Y	0.581	0.21
176_I	228_D	0.580	0.21
401_R	527_R	0.578	0.21
394_D	397_I	0.578	0.21
267_A	387_T	0.578	0.21
168_G	474_F	0.578	0.21
349_N	435_E	0.578	0.21
520_Y	535_H	0.578	0.21
26_C	427_G	0.577	0.21
262_G	305_N	0.577	0.21
497_E	503_Q	0.575	0.21
20_Y	328_V	0.573	0.21
313_P	390_D	0.573	0.21
106_V	130_F	0.572	0.21
441_K	445_A	0.571	0.21
49_L	76_Y	0.570	0.21
293_Y	345_S	0.570	0.21
383_G	390_D	0.569	0.21
49_L	135_F	0.569	0.21
117_N	280_F	0.569	0.21
154_Y	163_Y	0.569	0.21
474_F	477_S	0.568	0.21
53_K	226_Y	0.567	0.21
35_G	255_F	0.567	0.21
69_T	106_V	0.567	0.21
188_W	511_R	0.567	0.21
76_Y	181_E	0.567	0.21
367_K	429_K	0.566	0.21
163_Y	433_L	0.566	0.21
156_I	346_R	0.566	0.21
400_P	532_Q	0.565	0.21
288_L	376_D	0.564	0.21
73_P	519_V	0.564	0.21
504_Y	513_D	0.563	0.21
83_Y	101_F	0.562	0.20
267_A	531_P	0.562	0.20
125_A	128_G	0.561	0.20
113_H	295_I	0.561	0.20
209_Y	284_E	0.560	0.20
271_W	516_Y	0.560	0.20
200_L	386_R	0.560	0.20
172_L	235_S	0.559	0.20
265_I	287_L	0.559	0.20
227_Y	282_S	0.558	0.20
369_N	535_H	0.557	0.20
159_P	435_E	0.557	0.20
188_W	284_E	0.556	0.20
160_N	183_F	0.556	0.20
63_D	304_L	0.556	0.20
108_K	413_Y	0.556	0.20
284_E	482_I	0.556	0.20
400_P	542_R	0.555	0.20
99_Y	135_F	0.555	0.20
141_H	318_S	0.555	0.20
13_L	19_G	0.553	0.20
9_E	52_S	0.553	0.20
201_G	532_Q	0.552	0.20
154_Y	508_S	0.551	0.20
244_I	262_G	0.550	0.20
13_L	132_L	0.550	0.20
12_L	508_S	0.549	0.20
126_T	494_T	0.549	0.20
36_Y	214_I	0.548	0.20
167_E	228_D	0.548	0.20
28_I	71_Y	0.548	0.20
287_L	340_K	0.547	0.20
65_Y	86_K	0.546	0.20
110_L	121_I	0.546	0.20
507_S	522_G	0.546	0.20
262_G	312_L	0.546	0.20
351_I	358_V	0.545	0.20
527_R	532_Q	0.545	0.20
53_K	81_Y	0.545	0.20
65_Y	83_Y	0.544	0.20
265_I	439_S	0.544	0.20
13_L	354_V	0.544	0.20
294_D	352_R	0.542	0.20
57_F	81_Y	0.542	0.20
334_A	507_S	0.541	0.20
309_R	442_K	0.541	0.20
276_G	528_E	0.541	0.20
70_N	81_Y	0.540	0.20
537_A	542_R	0.539	0.19
531_P	535_H	0.539	0.19
136_I	188_W	0.537	0.19
108_K	117_N	0.536	0.19
357_K	436_K	0.535	0.19
29_N	52_S	0.534	0.19
219_N	451_Q	0.534	0.19
384_A	539_V	0.533	0.19
279_T	289_V	0.533	0.19
44_P	385_P	0.531	0.19
464_P	518_P	0.531	0.19
62_G	205_I	0.530	0.19
324_V	370_G	0.528	0.19
429_K	493_L	0.528	0.19
190_Y	207_D	0.527	0.19
55_E	78_P	0.525	0.19
397_I	524_R	0.525	0.19
277_R	388_W	0.525	0.19
275_W	400_P	0.525	0.19
62_G	541_R	0.525	0.19
332_L	412_W	0.524	0.19
194_Y	208_L	0.524	0.19
280_F	337_A	0.523	0.19
11_W	391_A	0.523	0.19
334_A	484_D	0.522	0.19
386_R	502_R	0.521	0.19
289_V	344_Y	0.521	0.19
188_W	200_L	0.520	0.19
274_E	404_A	0.518	0.19
342_Y	480_F	0.518	0.19
253_K	330_I	0.518	0.19
51_L	180_Y	0.518	0.19
104_S	197_D	0.518	0.19
401_R	531_P	0.517	0.19
96_T	265_I	0.517	0.19
248_L	453_G	0.517	0.19
270_H	274_E	0.517	0.19
263_W	422_L	0.517	0.19
51_L	406_V	0.516	0.19
50_I	188_W	0.516	0.19
39_V	274_E	0.515	0.18
416_L	437_A	0.514	0.18
129_K	155_E	0.514	0.18
339_Y	421_F	0.512	0.18
285_G	454_L	0.512	0.18
52_S	55_E	0.512	0.18
131_K	135_F	0.512	0.18
136_I	282_S	0.512	0.18
36_Y	95_I	0.512	0.18
279_T	472_Q	0.511	0.18
267_A	310_G	0.511	0.18
159_P	168_G	0.511	0.18
168_G	515_N	0.511	0.18
389_M	406_V	0.510	0.18
391_A	398_V	0.510	0.18
313_P	520_Y	0.510	0.18
72_Y	134_P	0.510	0.18
274_E	281_I	0.510	0.18
378_L	409_N	0.509	0.18
528_E	535_H	0.509	0.18
22_S	31_R	0.509	0.18
146_K	207_D	0.508	0.18
274_E	392_S	0.507	0.18
267_A	520_Y	0.506	0.18
115_G	435_E	0.506	0.18
455_Y	458_I	0.506	0.18
285_G	337_A	0.506	0.18
185_S	536_M	0.505	0.18
310_G	313_P	0.505	0.18
180_Y	220_K	0.505	0.18
110_L	510_S	0.504	0.18
384_A	402_E	0.504	0.18
57_F	244_I	0.504	0.18
499_K	513_D	0.504	0.18
116_Y	305_N	0.503	0.18
274_E	369_N	0.502	0.18
361_I	400_P	0.502	0.18
326_R	390_D	0.501	0.18
259_G	405_A	0.500	0.18
389_M	527_R	0.500	0.18
69_T	76_Y	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qdeA	2	0.943	100	0.786	Contact Map
2jg0A	1	0.6526	100	0.79	Contact Map
4wvaA	3	0.5092	100	0.805	Contact Map
3w7tA	1	0.9007	100	0.805	Contact Map
1lf6A	1	0.875	100	0.809	Contact Map
4j5tA	1	0.9393	100	0.81	Contact Map
1gaiA	1	0.511	100	0.813	Contact Map
3rrsA	2	0.9449	100	0.818	Contact Map
1v7wA	2	0.9228	100	0.825	Contact Map
4zlfA	2	0.9265	100	0.827	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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