GREMLIN Database
Q97TW3 - Second ORF in transposon ISC1078
UniProt: Q97TW3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 197 (167)
Sequences: 1830 (1399)
Seq/√Len: 108.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
78_N99_M3.1401.00
56_G137_W2.9651.00
21_I97_I2.9181.00
79_S109_V2.8461.00
79_S108_E2.8431.00
75_P107_N2.7191.00
111_E115_E2.6821.00
24_E141_K2.6451.00
27_V51_R2.5251.00
57_G64_G2.4791.00
68_S156_M2.4071.00
162_F165_S2.3311.00
98_V123_L2.3311.00
74_K77_L2.2931.00
87_R116_N2.1601.00
140_L162_F2.1081.00
80_K84_L1.9311.00
26_Y54_V1.9201.00
25_S51_R1.8441.00
152_F156_M1.7911.00
112_F116_N1.7871.00
70_S156_M1.7871.00
139_V172_D1.7581.00
99_M113_L1.7341.00
96_V121_V1.7201.00
58_I173_L1.6731.00
143_R162_F1.6651.00
138_A142_K1.6431.00
79_S112_F1.6391.00
135_G179_R1.6221.00
26_Y159_A1.6101.00
79_S107_N1.6071.00
58_I136_P1.5761.00
21_I78_N1.5181.00
75_P79_S1.5061.00
75_P108_E1.5031.00
140_L166_I1.5011.00
131_S134_E1.4891.00
176_S180_C1.4391.00
103_R106_G1.4331.00
27_V49_R1.4231.00
156_M160_T1.3991.00
113_L120_F1.3881.00
172_D175_Y1.3621.00
139_V143_R1.3611.00
25_S30_I1.3541.00
56_G133_A1.3391.00
45_V48_K1.3040.99
73_K104_I1.2780.99
135_G138_A1.2730.99
168_K173_L1.2690.99
173_L176_S1.2500.99
134_E176_S1.2490.99
24_E159_A1.2440.99
99_M120_F1.2290.99
35_G41_G1.2240.99
22_F102_A1.2230.99
101_N106_G1.2220.99
150_T154_T1.2020.99
74_K104_I1.2000.99
17_Y94_K1.1980.99
14_R17_Y1.1950.99
151_D154_T1.1900.99
75_P109_V1.1900.99
26_Y141_K1.1850.99
26_Y144_L1.1720.99
157_W161_R1.1600.99
25_S104_I1.1440.98
20_H58_I1.1440.98
38_K41_G1.1300.98
161_R171_N1.1260.98
167_S172_D1.1260.98
21_I55_V1.1130.98
73_K103_R1.0960.98
54_V159_A1.0910.98
160_T164_R1.0860.98
25_S53_A1.0850.98
98_V131_S1.0760.98
61_S174_T1.0460.97
176_S179_R1.0450.97
13_I16_G1.0360.97
59_T62_K1.0350.97
79_S83_I1.0300.97
107_N110_R1.0230.97
21_I99_M1.0210.97
146_S149_Y1.0170.97
20_H98_V1.0080.97
113_L118_V0.9990.96
99_M122_Y0.9990.96
83_I112_F0.9630.96
44_K157_W0.9610.95
138_A141_K0.9560.95
83_I115_E0.9540.95
132_P177_V0.9510.95
147_K158_D0.9450.95
106_G110_R0.9450.95
106_G122_Y0.9450.95
82_I112_F0.9390.95
108_E111_E0.9380.95
37_M42_G0.9300.95
154_T157_W0.9290.95
153_E158_D0.9280.95
168_K174_T0.9280.95
133_A137_W0.9260.94
161_R165_S0.9250.94
134_E180_C0.9240.94
23_D105_H0.9220.94
36_W142_K0.9170.94
48_K51_R0.9130.94
28_S155_L0.9120.94
175_Y178_K0.9040.94
171_N175_Y0.9040.94
21_I123_L0.8990.94
69_Y73_K0.8930.93
111_E114_E0.8870.93
94_K119_E0.8800.93
85_Y88_K0.8760.93
73_K81_D0.8760.93
78_N106_G0.8730.93
171_N178_K0.8540.92
73_K77_L0.8510.92
115_E153_E0.8480.91
140_L176_S0.8460.91
15_E180_C0.8330.91
24_E29_Y0.8270.90
63_E137_W0.8260.90
123_L131_S0.8230.90
40_G128_P0.8200.90
12_K16_G0.8160.90
171_N174_T0.8120.90
37_M41_G0.8090.89
21_I57_G0.8000.89
78_N129_D0.7770.87
76_S80_K0.7740.87
174_T178_K0.7730.87
78_N81_D0.7680.87
53_A72_Y0.7660.87
109_V122_Y0.7650.87
20_H25_S0.7640.87
156_M159_A0.7530.86
154_T165_S0.7530.86
71_T77_L0.7420.85
73_K102_A0.7420.85
63_E164_R0.7400.85
22_F128_P0.7360.84
74_K79_S0.7300.84
154_T162_F0.7300.84
152_F155_L0.7290.84
50_K53_A0.7280.84
32_K36_W0.7190.83
81_D104_I0.7180.83
31_N148_I0.7180.83
92_D168_K0.7170.83
172_D176_S0.7100.82
19_V57_G0.7070.82
35_G42_G0.7020.82
101_N125_P0.7000.81
64_G94_K0.7000.81
161_R164_R0.6990.81
104_I113_L0.6990.81
66_T163_L0.6950.81
52_F68_S0.6890.80
110_R114_E0.6870.80
167_S174_T0.6820.80
84_L88_K0.6790.79
71_T133_A0.6790.79
109_V112_F0.6750.79
143_R165_S0.6750.79
110_R120_F0.6710.79
39_V76_S0.6700.78
16_G60_I0.6630.78
91_K95_T0.6600.77
141_K159_A0.6600.77
27_V31_N0.6590.77
48_K52_F0.6570.77
92_D118_V0.6560.77
158_D161_R0.6540.77
19_V86_L0.6520.77
145_Y149_Y0.6520.77
99_M123_L0.6480.76
106_G165_S0.6400.75
78_N82_I0.6330.74
112_F115_E0.6320.74
15_E18_K0.6250.74
53_A102_A0.6240.73
99_M106_G0.6230.73
17_Y121_V0.6120.72
73_K127_S0.6090.72
92_D95_T0.6060.71
99_M125_P0.6040.71
98_V134_E0.5980.70
92_D96_V0.5980.70
12_K114_E0.5950.70
20_H180_C0.5950.70
35_G38_K0.5940.70
111_E116_N0.5930.70
17_Y96_V0.5860.69
140_L156_M0.5860.69
137_W173_L0.5820.68
149_Y154_T0.5730.67
49_R53_A0.5720.67
133_A163_L0.5710.67
155_L159_A0.5700.67
138_A155_L0.5700.67
77_L104_I0.5680.66
24_E137_W0.5670.66
123_L126_Y0.5670.66
172_D180_C0.5660.66
153_E165_S0.5660.66
162_F166_I0.5660.66
158_D162_F0.5590.65
81_D125_P0.5570.65
62_K177_V0.5570.65
28_S49_R0.5570.65
147_K159_A0.5550.65
69_Y160_T0.5540.64
51_R54_V0.5530.64
25_S37_M0.5520.64
70_S164_R0.5500.64
173_L177_V0.5500.64
113_L116_N0.5470.63
144_L162_F0.5470.63
161_R174_T0.5450.63
44_K47_P0.5440.63
135_G176_S0.5420.63
55_V123_L0.5410.63
48_K104_I0.5380.62
123_L179_R0.5370.62
147_K150_T0.5340.62
85_Y89_V0.5310.61
100_D105_H0.5300.61
97_I113_L0.5300.61
141_K145_Y0.5290.61
29_Y36_W0.5260.60
136_P163_L0.5250.60
71_T92_D0.5240.60
76_S108_E0.5220.60
25_S73_K0.5200.60
69_Y77_L0.5190.59
62_K173_L0.5140.59
92_D121_V0.5130.59
47_P53_A0.5090.58
13_I17_Y0.5070.58
19_V27_V0.5070.58
104_I134_E0.5040.57
24_E54_V0.5040.57
99_M110_R0.5030.57
126_Y141_K0.5010.57
98_V180_C0.5000.57
15_E123_L0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3f2kA 1 0.8782 100 0.265 Contact Map
4mdaA 1 0.8832 100 0.28 Contact Map
4u7bA 2 0.9848 100 0.417 Contact Map
4fcyA 4 0.8985 98.8 0.791 Contact Map
4fw1A 2 0.8376 97.2 0.861 Contact Map
4mq3A 1 0.6447 97.1 0.862 Contact Map
1c6vA 4 0.7411 97 0.864 Contact Map
1cxqA 2 0.6802 96.8 0.868 Contact Map
3l3uA 2 0.7614 96.8 0.869 Contact Map
4fw2A 2 0.7716 96.7 0.869 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.